Recent brain imaging studies using functional magnetic resonance imaging (fMRI) have implicated insula and anterior cingulate cortices in the empathic response to another’s pain. However, virtually nothing is known about the impact of the voluntary generation of compassion on this network. To investigate these questions we assessed brain activity using fMRI while novice and expert meditation practitioners generated a loving-kindness-compassion meditation state. To probe affective reactivity, we presented emotional and neutral sounds during the meditation and comparison periods. Our main hypothesis (...) was that the concern for others cultivated during this form of meditation enhances affective processing, in particular in response to sounds of distress, and that this response to emotional sounds is modulated by the degree of meditation training. The presentation of the emotional sounds was associated with increased pupil diameter and activation of limbic regions (insula and cingulate cortices) during meditation (versus rest). During meditation, activation in insula was greater during presentation of negative sounds than positive or neutral sounds in expert than it was in novice meditators. The strength of activation in insula was also associated with self-reported intensity of the meditation for both groups. These results support the role of the limbic circuitry in emotion sharing. The comparison between meditation vs. rest states between experts and novices also showed increased activation in amygdala, right temporo-parietal junction (TPJ), and right posterior superior temporal sulcus (pSTS) in response to all sounds, suggesting, greater detection of the emotional sounds, and enhanced mentation in response to emotional human vocalizations for experts than novices during meditation. Together these data indicate that the mental expertise to cultivate positive emotion alters the activation of circuitries previously linked to empathy and theory of mind in response to emotional stimuli.. (shrink)

Moral or ethical questions are vital because they affect our daily lives: what is the best choice we can make, the best action to take in a given situation, and ultimately, the best way to live our lives? Health ethics has contributed to moving ethics toward a more experience-based and user-oriented theoretical and methodological stance but remains in our practice an incomplete lever for human development and flourishing. This context led us to envision and develop the stance of a “living (...) ethics”, described in this inaugural collective and programmatic paper as an effort to consolidate creative collaboration between a wide array of stakeholders. We engaged in a participatory discussion and collective writing process known as instrumentalist concept analysis. This process included initial local consultations, an exploratory literature review, the constitution of a working group of 21 co-authors, and 8 workshops supporting a collaborative thinking and writing process. First, a living ethics designates a stance attentive to human experience and the role played by morality in human existence. Second, a living ethics represents an ongoing effort to interrogate and scrutinize our moral experiences to facilitate adaptation of people and contexts. It promotes the active and inclusive engagement of both individuals and communities in envisioning and enacting scenarios which correspond to their flourishing as authentic ethical agents. Living ethics encourages meaningful participation of stakeholders because moral questions touch deeply upon who we are and who we want to be. We explain various aspects of a living ethics stance, including its theoretical, methodological, and practical implications as well as some barriers to its enactment based on the reflections resulting from the collaborative thinking and writing process. (shrink)

When Locke mentions polygamy in his writings, he does not condemn the practice and, even seems to endorse it under certain conditions. This attitude is out of step with many of his contemporaries. Identifying the philosophical reasons that lead Locke to have this attitude about polygamy motivates our project. Because Locke never wrote a treatise on ethics, we look to number of different texts, but focus on An Essay Concerning Human Understanding and Essays on the Law of Nature, in order (...) to outline his basic ethical theory. We argue that this theory, the elements of which include moral mixed modes, the law of nature, and the comparison of these modes with this law, is broad enough to accommodate practices like polygamy. Our interpretation shows that Locke’s line of thought on marriage is strikingly flexible for the 17th century, and even compared to some contemporary public debates on marriage. (shrink)

BackgroundDescriptive studies examining publication rates and citation counts demonstrate a geographic skew toward high-income countries (HIC), and research from low- or middle-income countries (LMICs) is generally underrepresented. This has been suggested to be due in part to reviewers’ and editors’ preference toward HIC sources; however, in the absence of controlled studies, it is impossible to assert whether there is bias or whether variations in the quality or relevance of the articles being reviewed explains the geographic divide. This study synthesizes the (...) evidence from randomized and controlled studies that explore geographic bias in the peer review process.MethodsA systematic review was conducted to identify research studies that explicitly explore the role of geographic bias in the assessment of the quality of research articles. Only randomized and controlled studies were included in the review. Five databases were searched to locate relevant articles. A narrative synthesis of included articles was performed to identify common findings.ResultsThe systematic literature search yielded 3501 titles from which 12 full texts were reviewed, and a further eight were identified through searching reference lists of the full texts. Of these articles, only three were randomized and controlled studies that examined variants of geographic bias. One study found that abstracts attributed to HIC sources elicited a higher review score regarding relevance of the research and likelihood to recommend the research to a colleague, than did abstracts attributed to LIC sources. Another study found that the predicted odds of acceptance for a submission to a computer science conference were statistically significantly higher for submissions from a “Top University.” Two of the studies showed the presence of geographic bias between articles from “high” or “low” prestige institutions.ConclusionsTwo of the three included studies identified that geographic bias in some form was impacting on peer review; however, further robust, experimental evidence is needed to adequately inform practice surrounding this topic. Reviewers and researchers should nonetheless be aware of whether author and institutional characteristics are interfering in their judgement of research. (shrink)

The field of nanoscience and nanotechnology is expanding rapidly, promising great benefits for society in the form of better medicine, more efficient energy production, new types of materials, etc. Naturally, in order for the science and technology to live up to these promises, it is important to continue scientific research and development, but equally important is the ethical dimension. Giving attention to the social, ethical and legal aspects of the field, among others, will help in developing a fully responsible—and thereby (...) capable—science and technology. Nanoethics has emerged as a field concerned with such ethical issues related to nanoscience and nanotechnology. Even though this field is relatively new, a significant amount of literature has already been published. This paper focuses on three of the major issues which are discussed in the literature of nanoethics, and also points to a certain bias in this literature. Each quite different in nature, these issues are: (1) The naming and (2) the timing of and approach to the field, as well as (3) the issue of safety. As will be seen, these issues are almost exclusively discussed by ethicists, (throughout the article, the term’ethicist’ is used in a broad definition covering philosophers, social and political scientists as well as philosophers of science) thus having no direct influence on the work being carried out by scientists. One can argue, therefore, that this bias creates a distortion of the ethical debate, making it insufficient and misleading. Ultimately, this bias is caused by the lack of communication and collaboration between ethicists on the one hand, and nanoscientists on the other. Thus, an argument is made for the different disciplines to begin collaborating, so as to more effectively and responsibly develop the field of nanoscience. (shrink)

Medical students’ mask-making can provide valuable insights into personal and professional identity formation and wellness. A subset of first- and second-year medical students attending a medical school wellness retreat participated in a mask-making workshop. Faculty-student teams examined student masks and explanatory narratives using visual and textual analysis techniques. A quantitative survey assessed student perceptions of the experience. We identified an overarching theme: “Reconciliation/reclamation of authentic identity.” The combination of nonverbal mask-making and narrative offers rich insights into medical students’ experience and (...) thinking. This activity promoted reflection and self-care, while providing insight regarding personal and professional development. (shrink)

Background: Understanding is an important goal of the informed consent process in research. We sought to assess the interrater reliability (IRR) and concurrent validity of two measures of understanding in child and young adult subjects and their parents. Methods: We conducted a cross-sectional survey and interview-based study of children and young adults participating in a clinical trial for cancer, along with one parent per child or young adult subject. We estimated the IRR of the Semi-Structured Comprehension Interview (SSCI) and the (...) MacArthur Competence Assessment Tool for Clinical Research (MacCAT-CR). We also estimated concordance between the SSCI, the MacCAT-CR, and the Quality of Informed Consent (QuIC). Results: For our sample of 32 subjects (16 parent–child pairs), IRR estimates were high for total score on the SSCI (intraclass correlation coefficient [ICC] = 0.88, 95% confidence interval [CI] = 0.76–0.94), as well as on the understanding (ICC = 0.93, 95% CI = 0.86–0.97) and reasoning (ICC = 0.97, 95% CI = 0.94–0.98) subscales of the MacCAT-CR. IRR was lower for the appreciation subscale of the MacCAT-CR (ICC = 0.70, 95% CI = 0.47–0.84). Scores on the SSCI were strongly correlated with scores on the understanding subscale of the MacCAT-CR (Spearman's rho = 0.72, 95% CI = 0.48–0.85) and the QuIC (Spearman's rho = 0.66, 95% CI = 0.24–0.87). Mean administration time for the SSCI was 3.1 minutes (95% CI = 2.7–3.5 minutes). Conclusions: The SSCI is a valid and reliable measure of understanding for use with both pediatric and adult research participants. It is easy to administer and score consistently, even by nonprofessional raters. The SSCI is a promising tool for use by clinician-investigators to study, detect, and correct deficiencies in understanding among children, adolescents, and adults making decisions about research participation. (shrink)

Tentant de rompre avec une représentation de la sérendipité comme produit du hasard et de la chance relatifs à « l’esprit scientifique », il s’agit ici d’analyser comment la sérendipité peut être le produit d’une concordance des « temporalités de champs » résultant d’une combinatoire de temps d’habitus, d’activité et d’institution propres à chaque champ. Ces temporalités de champs rythmant leurs luttes pour le monopole de la pratique scientifique, elles constituent un point de concordance entre champs à partir desquels s’agencent (...) les conditions de production et d’identification d’une découverte « par sérendipité ». Une telle approche a, au reste, l’avantage de combler un point aveugle de la littérature sociologique et de proposer une analyse structuraliste du processus de découverte scientifique permettant de l’appréhender comme « pratique coordonnée d’institution ». (shrink)

We discuss how the Arab Spring is a reflection of the resiliency of the human rights regime. In order to accomplish this, we explore the extent to which the Arab Spring represents norm diffusion among Middle East and North Africa states. Specifically, we examine the cases of Tunisia, Egypt, and Bahrain and consider how economic and demographic changes created space for human rights discourse in these countries. We find that, in the case of MENA states, the Arab Spring represents significant (...) pressure from below. Access to new forms of social media allowed civil society to organize, publicize, and protest relatively efficiently. Social media expanded the potential role of individuals and created newly empowered latent human rights activists who emerged as leaders of the norm diffusion process. The resulting diffusion of human rights norms in the Arab region represents one of the most significant expansions of the human rights regime since the regime’s inception. (shrink)

The olfactory system was traditionally thought to lack a thalamic relay to mediate top-down influences from memory and attention in other perceptual modalities. Olfactory perception was therefore often described as an outlier among perceptual modalities. It was argued as a result that olfaction was a canonical example of a direct perception. In this paper we review functional and anatomical evidence which demonstrates that olfaction depends on both direct pathway connecting anterior piriform cortex to orbitofrontal cortex and an indirect thalamic circuit (...) connecting posterior piriform cortex and orbitofrontal cortices to the olfactory system. We argue that the indirect corticothalamic circuit has the structure to potentially mediate mediates top-down influences of memory and attention in olfactory perception. This suggests that olfaction is not an outlier after all. (shrink)

Biomedical research is increasingly carried out in low- and middle-income countries. International consensus has largely been achieved around the importance of valid consent and protecting research participants from harm. But what are the responsibilities of researchers and funders to share the benefits of their research with research participants and their communities? After setting out the legal, ethical and conceptual frameworks for benefit sharing, this collection analyses seven historical cases to identify the ethical and policy challenges that arise in relation to (...) benefit sharing. A series of recommendations address possible ways forward to achieve justice for research participants in low- and middle-income countries. (shrink)

The authors would like to correct a misspelling in the name of one of the authors due to a typographical error. The name should read Atur Turakhia, not Artur Turakhia. This does not change the conclusions or interpretations presented.

People struggle with religion and spirituality in several ways, including challenges in trusting God, confronting supernatural evil, tolerating other perspectives on religion, maintaining moral propriety, finding existential meaning, and managing religious doubt. These religious and spiritual struggles relate to both physical and mental health independently of other religious and distress factors. Causality in this connection needs further study, but evidence supports many potential causes and moderators of the link between R/S struggle and health. These include personality, social, and environmental influences, (...) including traumatic experiences and subcultural differences. Many theoretical questions remain unresolved, including how change in R/S struggle can predict or be predicted by change in health and other connected constructs, and how one might intervene to aid those who struggle with religious or spiritual challenges. Nonetheless, research momentum has grown, having already produced a wealth of information that underscores the need for greater attention to this domain. R/S struggle poses an important exception to generally positive overall associations between religion and well-being, though even R/S struggle may promote growth. This review offers a brief introduction to emerging psychological theory and research on R/S struggle with an emphasis on its relevance to wellness and illness. (shrink)

The field of nanotechnology and nanoscience is growing rapidly in many areas of research, from electronics to biomedicine to material science. Carbon nanotubes are receiving a lot of attention in the research due to their unique properties and many possible applications. This new material is a good example of how nanotechnology provides us with new opportunities, but at the same time leaves us a lot of unknowns to deal with. In order to deal with the unknowns we need to consider (...) both the science and the ethics of the different applications of this novel material. Nanoethics is the study of the ethical issues in nanotechnology. It is a relatively new field of study and a lot of different methods have been suggested in this area. In this article a method is suggested combining an existing ethical theory with a practical approach in order to do a case study of the ethical considerations of using carbon nanotubes in biomedicine. For the case study to be of practical significance the scientific characteristics and properties of carbon nanotubes are reviewed to give the reader an overview of the research field. (shrink)

During the education of scientists at the university level the students become more and more specialized. The specialization of the students is a consequence of the scientific research becoming specialized as well. In the interdisciplinary field of nanoscience the importance of specialization is also emphasized throughout the education. Being an interdisciplinary field of study the specialization in this area is not focused on scientific disciplines, but on the different branches of the research. Historically ethics has not been a priority in (...) science education, however, in recent years the importance of such teachings has been highly recognize especially in medicine, biotechnology and engineering. The rapid development, the many new and unknown areas and the highly specialized focus of nanotechnology suggest the importance of having ethically competent researchers. In this article the importance of ethical competence in nanoscience research is argued for by an example of a dilemma that could occur in a research project. The dilemma is analyzed using two different ethical views, generating two different choices for action. It is seen that the dilemma can have more than one solution and that ethical competence can help in justifying the choice of solution in a specific situation. Furthermore it is suggested that a way to reach this competence is through education in ethics incorporated into the nanoscience education curriculum. (shrink)

"Law week 2005 highlights." Ethos: Official Publication of the Law Society of the Australian Capital Territory, (196), pp. 33.

Qu'entendre par modernité? Résulte-t-elle d'une transposition des schèmes théologiques et des dispositifs théologico-politiques propres au christianisme médiéval, ou bien s'est-elle affirmée contre son propre passé théologique, en rupture avec les formes héritées du passé? Et comment situer, dans ce processus, les philosophies de Hobbes et de Spinoza, comprises tantôt comme héritières des théologies de la toute-puissance divine, de l'augustinisme ou de la Réforme, tantôt comme inaugurant le.

The author, the mother of two children in Amsterdam, describes her birth experiences, the first in the hospital, the second at home.

When the Argonauts reach the island of Lemnos, Apollonius of Rhodes tells us, they send their herald Aethalides to the ruler of the island. Such a means of establishing contact and requesting safe passage was the norm in the Homeric world; there heralds acted as intermediaries between commanders and subordinates or between groups of people. In preliterate societies, heralds facilitated communication: messages were transmitted through memorization and repetition rather than by means of writing. While verbatim repetition was no doubt a (...) necessary feature of this form of communication, its wholesale transference into Homeric poetry was not necessarily the logical corollary. Nonetheless, we know of such repetitions precisely because of their appearance in the Homeric poems. It is now widely accepted that such passages are a result of the oral style of composition in which the oral poet repeats passages just as he uses shorter formulaic phrases. The debate embedded in the A-scholia of the Iliad suggests that repeated passages were a source of contention already in antiquity. While it is more common to see the scholiasts trying to decide which passage is ‘correct’ and which should be athetized, this provides evidence that athetization was not a unanimous impulse. The scholiast defends 2.60–71, part of which is repeated for the third time, against Zenodotus. (shrink)

Hotchin, Peter Around the middle of the 20th century the UK philosopher Elizabeth Anscombe had become critical of ethical doctrines that have no reference to the good. She was concerned that the notions of moral duty and obligation had been rendered anchorless because of an attenuation in our understanding of what the good consists in. Bereft of an anchor, ethical doctrines had, in her view, lost contact with human needs and desires. Anscombe's concern was that of someone from a (...) major school of thought known as 'virtue ethics', and her criticism was aimed at another major school of thought, that of 'deontology'. (shrink)

Hotchin, Peter Review of: Humanism: A very short introduction, by Stephen Law, Oxford: Oxford University Press, 2011.

Today, a major challenge for climate science is to overcome what is called the “usability gap” between the projections derived from climate models and the needs of the end-users. Regional Climate Models (RCMs) are expected to provide usable information concerning a variety of impacts and for a wide range of end-users. It is often assumed that the development of more accurate, more complex RCMs with higher spatial resolution should bring process understanding and better local projections, thus overcoming the usability gap. (...) In this paper, I rather assume that the credibility of climate information should be pursued together with two other criteria of usability, which are salience and legitimacy. Based on the Swiss climate change scenarios, I study the attempts at meeting the needs of end-users and outline the trade-off modellers and users have to face with respect to the cascade of uncertainty. A conclusion of this paper is that the trade-off between salience and credibility sets the conditions under which RCMs can be deemed adequate for the purposes of addressing the needs of end-users and gearing the communication of the projections toward direct use and action. (shrink)

Depuis plusieurs décennies, la numérisation des textes anciens et les progrès du TAL pour les traiter et les interroger ont largement modifié nos habitudes de travail. Il est désormais possible d’obtenir des données quantitatives massives qui affinent notre perception des phénomènes linguistiques et stylistiques dans des corpus écrits dans des états de langue anciens. Les corpus numériques créés depuis maintenant près d’un quart de siècle permettent d’envisager plus facilement la dynamique du...

Abstract An important strand of theories of practice stress that individuals' practical knowledge, i.e., their ability to act in appropriate and/or effective ways, is mainly tacit. This means that the social scientist cannot find out about this knowledge by simply asking the individuals she studies to articulate how it is appropriate and/or effective to act in various circumstances. In this paper, I pursue the proposal that the method of participant observation may be used to find out about individuals' practical knowledge. (...) Surprisingly, the literature does not contain any systematic and comprehensive discussion of this suggestion. I distinguish and exemplify four types of observation that are indicative of individuals' practical knowledge. The observations may serve as a basis for the social scientist's formulations of this knowledge. Further, I point to two main ways in which things may go wrong when the social scientist uses participant observation to find out about individuals' practical knowledge. I argue that the social scientist can make reasonably sure to avoid these two potential difficulties. Accordingly, I conclude that these difficulties do not undermine the effectiveness of the method. In this sense, social scientists are right to use the method of participant observation to find out about individuals' practical knowledge. (shrink)

In the recent methodological individualism-holism debate on explanation, there has been considerable focus on what reasons methodological holists may advance in support of their position. We believe it is useful to approach the other direction and ask what considerations methodological individualists may in fact offer in favor of their view about explanation. This is the background for the question we pursue in this paper: Why be a methodological individualist? We start out by introducing the methodological individualism-holism debate while distinguishing two (...) forms of methodological individualism: a form that says that individualist explanations are always better than holist accounts and a form that says that providing intervening individualist mechanisms always makes for better explanations than purely holist ones. Next, we consider four lines of reasoning in support of methodological individualism: arguments from causation, from explanatory depth, from agency, and from normativity. We argue that none of them offer convincing reasons in support of the two explanatory versions of individualism we consider. While there may well be occasions in which individualists’ favorite explanations are superior, we find no reason to think this always must be the case. (shrink)

Ivancovsky et al.'s Novelty-Seeking Model suggests several mechanisms that might underlie developmental change in creativity and curiosity. We discuss how these implications both do and do not align with extant developmental findings, suggest two further elements that can provide a more complete developmental account, and discuss current methodological barriers to formulating an integrated developmental model of curiosity and creativity.

Mathematical models are often expected to provide not only predictions about the phenomenon that they represent, but also explanations. These explanations are answers to why-questions and particularly answers to why the predicted phenomenon should occur. For instance, models can be used to calculate when the next total solar eclipse will happen, and then to explain why it will take place on July 2, 2019. In this regard we can obtain explanations from a model if we can solve the model equations (...) which govern the phenomenon under study. But some equations have no explicit solution or are too complicated to solve. In these cases it is difficult for a... (shrink)

This article discusses what is involved in having full moral status, as opposed to a lesser degree of moral status and surveys different views of the grounds of moral status as well as the arguments for attributing a particular degree of moral status on the basis of those grounds.

In this article, I offer a partial analysis of the role of values in qualitative data collection in social research. The partial analysis shows that nonepistemic values have both required and permissible roles to play during this phase of research. By appeal to the analysis, I reject the ideal of value-free science as applied to qualitative data collection, and I demonstrate why two alternative ideals should likewise be dismissed as standards for values in qualitative data collection. Also, I briefly discuss (...) the extent to which the partial analysis carries over to quantitative data collection in social research. (shrink)

One issue of dispute between methodological individualists and methodological holists is whether holist explanations are dispensable in the sense that individualist explanations are able to do their explanatory job. Methodological individualists say they are, whereas methodological holists deny this. In the first part of the paper, I discuss Elder-Vass’ version of an influential argument in support of methodological holism, the argument from emergence. I argue that methodological individualists should reject it: The argument relies on a distinction between individualist and holist (...) explanations that they find unacceptable and Elder-Vass’ reasons in support of his way of drawing this distinction are not good ones. In the second part, I examine what, if anything, would be good reasons in support of a particular way of differentiating between individualist and holist explanations. I propose that a good reason is one which shows, in an acceptable manner, that the distinction, drawn in the same way in all contexts, is useful from the perspective of offering explanations of the social world. I show that if this criterion is adopted, it will result in a fruitful reorientation of the whole debate between methodological individualists and methodological holists. (shrink)

This paper discusses the so-called non-interference assumption (NIA) grounding causal inference in trials in both medicine and the social sciences. It states that for each participant in the experiment, the value of the potential outcome depends only upon whether she or he gets the treatment. Drawing on methodological discussion in clinical trials and laboratory experiments in economics, I defend the necessity of partial forms of blinding as a warrant of the NIA, to control the participants’ expectations and their strategic interactions (...) with the experimenter. (shrink)

Social scientists associate agent-based simulation (ABS) models with three ideas about explanation: they provide generative explanations, they are models of mechanisms, and they implement methodological individualism. In light of a philosophical account of explanation, we show that these ideas are not necessarily related and offer an account of the explanatory import of ABS models. We also argue that their bottom-up research strategy should be distinguished from methodological individualism.

Recent debates about inequality have focused almost exclusively on the distribution of wealth and disparities in income, but little notice has been paid to the distribution of free time. Free time is commonly assumed to be a matter of personal preference, a good that one chooses to have more or less of. Even if there is unequal access to free time, the cause and solution are presumed to lie with the resources of income and wealth. In Free Time, Julie (...) Rose argues that these views are fundamentally mistaken. First, Rose contends that free time is a resource, like money, that one needs in order to pursue chosen ends. Further, realizing a just distribution of income and wealth is not sufficient to ensure a fair distribution of free time. Because of this, anyone concerned with distributive justice must attend to the distribution of free time. On the basis of widely held liberal principles, Rose explains why citizens are entitled to free time—time not committed to meeting life's necessities and instead available for chosen pursuits. The novel argument that the just society must guarantee all citizens their fair share of free time provides principled grounds to address critical policy choices, including work hours regulations, Sunday closing laws, public support for caregiving, and the pursuit of economic growth. Delving into an original topic that touches everyone, Free Time demonstrates why all citizens have, in the words of early labor reformers, a right to "hours for what we will.". (shrink)

It is currently common to conceive of the classic methodological individualism–holism debate in level terms. Accordingly, the dispute is taken to concern the proper level of explanations in the social sciences. In this paper, I argue that the debate is not apt to be characterized in level terms. The reason is that widely adopted notions of individualist explanations do not qualify as individual-level explanations because they span multiple levels. I defend this claim relative to supervenience, emergence, and other accounts of (...) the social world as levelled. Moreover, I discuss the consequences of this finding for the ongoing methodological individualism–holism debate. (shrink)