A comprehensive account of the role of the imagination in Hegel's philosophy.

_A comprehensive account of the role of the imagination in Hegel's philosophy._.

A Hegelian reading of good and bad luck -- In Shakespearean drama (phen. of spirit, King Lear, Othello, Hamlet, a Midsummer night's dream) -- Tearing the fabric: Hegel's Antigone, Shakespeare's Coriolanus, and kinship-state conflict (phen. of spirit c. 6, Judith Butler's Antigone, Coriolanus) -- Aufhebung and anti-aufhebung: geist and ghosts in Hamlet (phen. of spirit, Hamlet) -- The problem of genius in King Lear: Hegel on the feeling soul and the tragedy of wonder (anthropology and psychology in the encyclopaedia, Philosophy (...) of mind, King Lear) -- Richard II's mirror and the alienation of the Universal Will (of the I that is a We) (Richard II, phen. of spirit c. 5) -- Falstaff and the politics of wit: negative infinite judgment in a culture of alienation (Henry IV parts I & II, phen. of spirit c. 6, philosophy of right) -- Henry V's unchangeableness: his rejection of wit and his posture of virtue reinterpreted in the light of Hegel's theory of virtue (philosophy of right, Henry V) -- Hegel's theory of crime and evil: (re)tracing the rights of the sovereign self (aesthetics, phen. of spirit, phil. of right, Richard II through to Henry V) -- Richard III, Hamlet, Macbeth and Henry V: conscience, hypocrisy, self-deceit and the tragedy of ethical life (phil. of right, Richard III, Hamlet, Macbeth, Henry V) -- Negation of the negative infinite judgment versus sublation of it: punishment vs. pardon (phil. of right, phen. of spirit c. 6 and Henry VIII) -- Universal wit : the absolute theater of identity (phen. of spirit c. 6 and 8, Pericles, the Tempest) -- Absolute infections and their cure (phen. of spirit c. 6, the Winter's tale). (shrink)

_Study of self-consciousness in Hegel and Shakespeare._.

Given the importance of imagination for Kant, Fichte and Schelling, it is significant that the word only comes up once in Hegel's Phenomenology of Spirit, and that it is not a chapter heading alongside "Sense-Certainty," "Perception," "Understanding" and "Reason." ;Part I. "Imagination in Theory" looks at the development in Hegel's theory of imagination from the Differenzschrift and Faith and Knowledge, through three different versions of the Philosophy of Spirit . Part II. "Imagination in Practice," focuses on the final moment of (...) the imagination according to the 1830 Philosophy of Spirit--Sign-making Phantasie. I discuss two examples--the artist's activity as described in the Aesthetics, and the 'religion of imagination'--Hinduism as Hegel understood it in the Lectures on the Philosophy of Religion. Part III synthesizes the two previous parts, showing that the Phenomenology of Spirit is the culmination of the imagination's theoretical and practical activity: while in theory imagination is the middle moment of Vorstellen, practically it is at the heart of Aufhebung and thus of Spirit's inception and development. The Phenomenology is the story of consciousness' progress through its self-presentations. Imagination is therefore present throughout the entire book. I do not engage the moments of the Phenomenology, but focus instead on the single appearance of the word imagination in the Preface, and on how Hegel reinterprets Fichte's wavering imagination as a moment within the reflection--the "medium" of this 'Science of Experience.' ;Between 1801-1807 language becomes an increasingly important moment of imagination; by 1830 the externalizing of representations in communication is a moment of imagination. Hegel's psychology of the genesis of imagination and its moments reveals Spirit to be the community of interpreters. In the thesis Hegel's imagination is thought through to the Phenomenology, however, it is in the final transition of the Phenomenology--from Religion to Absolute Knowing, from picture thinking to knowing according to the Concept--that Hegel thinks the imagination through to its end. My Epilogue briefly discusses that transition, and the end of imagination in Absolute Knowing. (shrink)

Hegel’s “Absolute Knowing” and Shakespeare’s Troilus and Cressida are tragi-comic consternations. They are theatres of ethical panentheism: they present dramatic “absolute” ethical interpretations and actions, each of which is at once ungrounded and completely seeded. I start with the etymology of “consternation.” Then I discuss the comic vs. tragic interpretations of Hegel’s Phenomenology of Spirit, arguing it is a consternating tragi-comedy. I analyze the predicate “absolute” in terms of consternations, in a few passages of the book. I elaborate especially upon (...) phenomenological reasoning’s Sache selbst. In the Phenomenology, reason develops by thinking the absolute thing through culture, politics, morality, and religion, reaching completion in “Absolute Knowing.” That absolute is reason’s comprehensive insight into its phenomenological absolutes, and its own absolute sublating. Northrop Frye’s cited claim about myth can be understood in this phenomenological way. With all this in hand, Hegel’s science of experience is formally complete. But the experience of Absolute Knowing is still consternation. To capture the consternating essence of sublation – a consternation by which experience becomes something it was not before – I season this formal science with Shakespeare’s “comedy” Troilus and Cressida, revealing its structural roots to be consternations. (shrink)

Part I discusses what kind of ‘advances’ occur in Hegel's works, particularly his Philosophy of Nature. I then discuss evolution and extinction in relation to these advances. I summarize Errol Harris' view that Hegel's advances are consistent with current evolutionary theory and then critique this view using articles by Cinzia Ferinni and Alison Stone. I discuss an alternative, post-Kantian Hegelianism which dialectically unites the nature of our cognition with us as subjects that cognize (spirit). For that, I draw on Hegel's (...) claim that ‘The True is just as much Substance as Subject’, and I show how that claim is complicated in a helpful way when applied to the multiple kinds of ‘subjects’ in the Philosophy of Nature. Part II highlights the implications of biological mass extinction for these differing Hegelian theories. Part III brings the above post-Kantian dialectical Hegelianism together with the final chapter of the Phenomenology of Spirit in order to align Hegelian terminology with current solutions for mass extinction: ‘Absolute Knowing’ is a self-sacrificing and a recollecting that reinstates the subject in and through nature; such knowing generates dialectically holistic logics of survival. This recollection of life produces neither abstract spiritual self-consciousness nor a mere ‘gallery’ of extinct life forms. It is philosophical responsibility, identity through natural differences, Absolute Spirit ‘tarrying’ with its world. 21st century Hegelians should be environmentalists on Hegel's terms, a surprising conclusion given that Hegel did not anticipate environmental problems. Hegel's Philosophy of Nature may in turn help environmentalists argue against unacknowledged and badly conceived philosophies of nature. Hegel's work is not reducible to either naturalism or metaphysical idealism: reading Hegel's Philosophy of Nature in conjunction with his Phenomenology of Spirit reveals ways in which a subject, widely and complexly defined at different levels (including different species), is dialectically inseparable from substance, equally widely and complexly defined. This helps us to understand the natural depths of Spirit, which we are at risk of losing. (shrink)

Launched by the United Nations in 2000, the Global Compact (GC) promotes private sector compliance with 10 basic principles covering human rights, labour standards, the environment, and anti‐corruption. Its sponsors aim to establish a global corporate social responsibility (CSR) network based on a pledge to observe the 10 principles adopted by companies across the range of company size and regional origin, backed by a modest reporting system and collaborative programmes. The author analyzes the GC's progress toward building a global network (...) from its launch through 2006 and finds that, while the GC's nominal membership base of nearly 3000 companies makes it the largest system among collective action institutions (CAIs) for corporate responsibility, the GC has not reached ‘critical mass’. Deficiencies in its nascent global network include limited market penetration among the largest corporations, a membership heavily weighted toward Western European companies, and major weaknesses in compliance with its reporting system. The author concludes that the GC must improve both penetration and compliance if it is to succeed in building a global standard for CSR. (shrink)

En 1997, Hong Kong volvió a China en el marco de la gobernanza conocida como «Un país, dos sistemas», que fue ideado para permitir a la China continental seguir siendo «socialista», mientras Hong Kong podía mantener su sistema capitalista. Sin embargo, la estrategia retórica y legal de mantener metafórica y constitucionalmente la distancia entre los dos lugares y seguir afirmando su soberanía y unidad, es ambigua y contradictoria. Este artículo explora estas ambiguas contradicciones (estratégicas, ideológicas y retóricas) y tras ello (...) su impacto en el debate sobre la democracia y el sufragio en Hong Kong, que su constitución, la Ley básica, promete para el futuro. (shrink)

Launched by the United Nations in 2000, the Global Compact (GC) promotes private sector compliance with 10 basic principles covering human rights, labour standards, the environment, and anti-corruption. Its sponsors aim to establish a global corporate social responsibility (CSR) network based on a pledge to observe the 10 principles adopted by companies across the range of company size and regional origin, backed by a modest reporting system and collaborative programmes. The author analyzes the GC's progress toward building a global network (...) from its launch through 2006 and finds that, while the GC's nominal membership base of nearly 3000 companies makes it the largest system among collective action institutions (CAIs) for corporate responsibility, the GC has not reached 'critical mass'. Deficiencies in its nascent global network include limited market penetration among the largest corporations, a membership heavily weighted toward Western European companies, and major weaknesses in compliance with its reporting system. The author concludes that the GC must improve both penetration and compliance if it is to succeed in building a global standard for CSR. (shrink)

Literary beauty was once understood as intertwining sensations and ideas, and thus as providing subjective and objective reasons for literary appreciation. However, as theory and philosophy developed, the inevitable claims and counterclaims led to the view that subjective experience was not a reliable guide to literary merit. Literary theory then replaced aesthetics as did philosophy’s focus on literary truth. Along with the demise of the relevance of sensations, literary form also took a back seat. This suggested to some that either (...) literature communicated truth like any other literal form of communication or it was a mere diversion: a springboard to harmless reverie or daydreaming. Neither response satisfactorily captured what was distinctive about literature: the love readers can have for literary texts and the edification or insight claimed of works within each culture’s respective catalogue of classics. However, a concept of literary beauty has again become viable due to developments in theories of pleasure and imagination. If the defining aspect of literature is the imaginative engagement it occasions, and if this imagining is constrained by plausibility and endorsed as effective relative to our goals, ideals, and interests, then literature is not reduced to either mere fact or wish fulfillment. An account of literary beauty is available which defines literature accordingly and explains how subjective and objective reasons for appreciation intertwine to evoke pleasure and insight. (shrink)

The Oxford Encyclopedia of Literary Theory presents a broad and in-depth overview of every aspect of literary theory, both traditional and contemporary. Around 180 full-length essays written by international experts illustrate the problems, the concepts, and the methodologies that arise when we discuss literary criticism, offering the most comprehensive exposition and analysis currently available of literary theory in all its many dimensions.

Dans son roman Le gone du Chaâba, Azouz Begag (lui-même né en 1957 à Villeurbanne) nous fait connaître la vie d’un jeune Français, né de parents algériens, qui grandit dans un bidonville avant de transiter vers un appartement à Lyon. Ce récit est souvent utilisé aux États-Unis pour aider les étudiants en licence à mieux imaginer la vie des immigrés algériens en France, y compris leur contact au quotidien avec les institutions de l’État français. Pourtant, si le travail d’Alice Conklin (...) sur la... (shrink)

Instead of considering the question of the role of Christian women in ministry by providing a new exegesis of contested passages it is helpful to provide a new approach to the matter. This new approach is to explore the nature of New Testament prophecy. The line drawn between prophecy and teaching is not as clear as some conservatives contend, since both make use of Scripture. Women are named as prophets in the Bible and some female prophets have had their words (...) recorded as Scripture. Paul ranks prophets more highly than teachers in 1 Cor. 12.28. Therefore, if women can prophesy they can also teach. This approach provides a way of biblically affirming the full ministry of women within the Christian Church. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Feminist Studies 44, no. 2. © 2018 by Feminist Studies, Inc. 491 Jennifer Anne Moses The Teacher It didn’t start percolating out until years—decades—later, and by that time even the youngest of what we’d soon be calling “the victims ” were in their early fifties, with husbands and children and grandchildren of their own, or not, with houses, careers, garages stuffed to the gills with lifetimes’ worth of (...) patio furniture and forgotten Halloween costumes and broken lamps and tools. Someone saw someone who knew someone, who’d remembered someone, and again the stories were abroad, the whisperings, only this time it was with heavy sighs of regret and anxious handwringing: How could we not have known better? How could our parents not have known? And if they, the parents, had known—and surely some of them had—they were too busy themselves, and perhaps too ashamed, too abashed to see it for what it was, and after all, busy and perplexed with their own lives, their own divorces or philandering husbands or careers that felt like prison, with alcoholism and dying parents, with inheritances and bright futures withered to nothing. All those bright promises of their bright and perfect childhoods curling like so many brown November leaves. His name was Mr. Bryce—Evan Bryce, as we later came to call him—and he was among the most popular, perhaps the most popular, of the upper-school teachers, with a yearly following of students lucky enough not only to have been enrolled in one of his classes, but allowed, as if by virtue of their own charmed stars, their own charming uniqueness, to lean against his desk during free time, or joke around with him as he walked, his battered book bag in hand, toward the lunchroom. He 492 Jennifer Anne Moses taught history and geography; his classroom was the first on the left as you rounded the corner from the art room to the open-air corridor that the upper school classrooms abutted. Beyond that strip of covered poured white concrete was a kind of rough lawn, made patchy by years of boys tackling each other there or throwing a Frisbee around, and beyond that, on the other side of a narrow gravel road used only, as far as we could tell, by the school’s groundskeepers whose names, despite their ubiquitous presence, we didn’t know, was the first of the playing fields, used for hockey and soccer. Beyond the playing field was a covered sports arena with a huge swooping roof like the wings of a swan, and beyond that, hills covered with mowed green grass—perfect for tumbling down on bright spring days—and others still wooded, watered with streams and crisscrossed with trails. We knew the trails of course— some of our natural science classes took place in the woods—and we knew each of the hills and fields as well, each tree, each row of boxwoods or pines, until finally, out there, beyond the school grounds, was where the residents of the town lived in red-brick development houses of two and sometimes one-and-a-half floors, in modified colonials and California-style split-levels, each on its own small patch of lawn, and a garage. We felt sorry for the people who lived in those developments (we always called them developments, never neighborhoods, which is where we lived), but we rarely wondered what their lives might be like, or where their children, if they had them, might go to school. Our houses weren’t like that, of course. Susie Bluestone’s house was old, tall and thin, in a neighborhood of other old, tall, thin houses, with Oriental carpets running up the stairways, and a laundry shoot that the children were forbidden to play in and played in anyway. My best friend Nan Jones lived in a farmhouse on the top of a hill and wasn’t allowed to use the guestroom bathroom, even though her room was right next to it; her mother kept horses and her father had once been some kind of fencing champion. There were black-and-white pictures of him, in black frames, on the walls... (shrink)

As the title of this book implies, a historical perspective is taken in looking at the philosophy of Hegel. This is an attempt to better understand Hegel by reviewing the philosophic thought that was prevalent prior to his time, as well as looking at reaction to Hegel himself. In addition Rockmore does a brief overview of Hegel’s philosophy, including his four major works. The book has been divided into three sections: “Before Hegel,” “Hegel,” and “After Hegel.”.

College cheating is prevalent, with rates ranging widely from 9 to 95%. Research has been exclusively conducted with enrolled college students. This study examined the prevalence of cheating in a sample of college alumni, who risk less in disclosing academic dishonesty than current students. A total of 273 alumni reported on their prevalence and perceived severity of 19 cheating behaviors. The vast majority of participants report having engaged in some form of cheating during their undergraduate career. The most common forms (...) of cheating were “copying from another student's assignment” and “allowing others to copy from your assignment.” More students reported cheating in classes for their major than other classes. Males and females cheated at the same rates in classes for their major, and males reported higher rates of cheating than females in nonmajor classes. Respondents reported that their top reasons for cheating were “lack of time” and “to help a friend.”. (shrink)

Many philosophers advocate a change in our thinking in order to move beyond an anthropocentric view of the environment. In order to achieve the kind of thinking that makes for sound environmental thinking, we have to look more deeply into the nature of thought and to revise the relation between thought directed outward to the world and thought directed inwardly to thought itself. Only with such insight can we begin to think soundly about the environment. Thought exhibits a characteristic that (...) makes it hard to think environmentally soundly. This characteristic is the inability to think of something without at thesame time making it one’s property. In other words, if sound environmental thinking means moving beyond anthropocentric attitudes and, for example, extending moral categories to creatures other than humans, then we need to address how our thinking turns everything into “mine” before we go about establishing a theory about how that extension should take shape. Hegel is the philosopher who most deeply analyses the inevitable, yet dangerous role of “mining”—in the sense of “making mine,” in the act of thinking. This potentially problematic character of thought risks making a number of otherwise soundenvironmental ways of thinking, unsound. However, we can provide a balance for this problematic characteristic in our thinking. (shrink)

One of six commentaries on “Obesity: Chasing an Elusive Epidemic,” by Daniel Callahan, from the January‐February 2013 issue.

This handbook presents a comprehensive introduction to the core areas of philosophy of education combined with an up-to-date selection of the central themes. It includes 95 newly commissioned articles that focus on and advance key arguments; each essay incorporates essential background material serving to clarify the history and logic of the relevant topic, examining the status quo of the discipline with respect to the topic, and discussing the possible futures of the field. The book provides a state-of-the-art overview of philosophy (...) of education, covering a range of topics: Voices from the present and the past deals with 36 major figures that philosophers of education rely on; Schools of thought addresses 14 stances including Eastern, Indigenous, and African philosophies of education as well as religiously inspired philosophies of education such as Jewish and Islamic; Revisiting enduring educational debates scrutinizes 25 issues heavily debated in the past and the present, for example care and justice, democracy, and the curriculum; New areas and developments addresses 17 emerging issues that have garnered considerable attention like neuroscience, videogames, and radicalization. The collection is relevant for lecturers teaching undergraduate and graduate courses in philosophy of education as well as for colleagues in teacher training. Moreover, it helps junior researchers in philosophy of education to situate the problems they are addressing within the wider field of philosophy of education and offers a valuable update for experienced scholars dealing with issues in the sub-discipline. Combined with different conceptions of the purpose of philosophy, it discusses various aspects, using diverse perspectives to do so. Contributing Editors: Section 1: Voices from the Present and the Past: Nuraan Davids Section 2: Schools of Thought: Christiane Thompson and Joris Vlieghe Section 3: Revisiting Enduring Debates: Ann Chinnery, Naomi Hodgson, and Viktor Johansson Section 4: New Areas and Developments: Kai Horsthemke, Dirk Willem Postma, and Claudia Ruitenberg. (shrink)

BackgroundClinical ethics consultations can be complex interventions, involving multiple methods, stakeholders, and competing ethical values. Despite longstanding calls for rigorous evaluation in the field, progress has been limited. The Medical Research Council proposed guidelines for evaluating the effectiveness of complex interventions. The evaluation of CEC may benefit from application of the MRC framework to advance the transparency and methodological rigor of this field. A first step is to understand the outcomes measured in evaluations of CEC in healthcare settings. ObjectiveThe primary (...) objective of this review was to identify and map the outcomes reported in primary studies of CEC. The secondary objective was to provide a comprehensive overview of CEC structures, processes, and roles to enhance understanding and to inform standardization.MethodsWe searched electronic databases to identify primary studies of CEC involving patients, substitute decision-makers and/or family members, clinicians, healthcare staff and leaders. Outcomes were mapped across five conceptual domains as identified a priori based on our clinical ethics experience and preliminary literature searches and revised based on our emerging interpretation of the data. These domains included personal factors, process factors, clinical factors, quality, and resource factors. ResultsForty-eight studies were included in the review. Studies were highly heterogeneous and varied considerably regarding format and process of ethical intervention, credentials of interventionist, population of study, outcomes reported, and measures employed. In addition, few studies used validated measurement tools. The top three outcome domains that studies reported on were quality, process factors, and clinical factors. The majority of studies examined multiple outcome domains. All five outcome domains were multidimensional and included a variety of subthemes.ConclusionsThis scoping review represents the initial phase of mapping the outcomes reported in primary studies of CEC and identifying gaps in the evidence. The confirmed lack of standardization represents a hindrance to the provision of high quality intervention and CEC scientific progress. Insights gained can inform the development of a core outcome set to standardize outcome measures in CEC evaluation research and enable scientifically rigorous efficacy trials of CEC. (shrink)

Many philosophers advocate a change in our thinking in order to move beyond an anthropocentric view of the environment. In order to achieve the kind of thinking that makes for sound environmental thinking, we have to look more deeply into the nature of thought and to revise the relation between thought directed outward to the world and thought directed inwardly to thought itself. Only with such insight can we begin to think soundly about the environment. Thought exhibits a characteristic that (...) makes it hard to think environmentally soundly. This characteristic is the inability to think of something without at thesame time making it one’s property. In other words, if sound environmental thinking means moving beyond anthropocentric attitudes and, for example, extending moral categories to creatures other than humans, then we need to address how our thinking turns everything into “mine” before we go about establishing a theory about how that extension should take shape. Hegel is the philosopher who most deeply analyses the inevitable, yet dangerous role of “mining”—in the sense of “making mine,” in the act of thinking. This potentially problematic character of thought risks making a number of otherwise soundenvironmental ways of thinking, unsound. However, we can provide a balance for this problematic characteristic in our thinking. (shrink)

Interoceptive processes emanating from baroreceptor signals support emotional functioning. Previous research suggests a unique link to fear: fearful faces, presented in synchrony with systolic baro...

Including more than 150 color images—several rarely seen before—drawn from the Royal Collection and the J. Paul Getty Museum, this volume accompanies an exhibition of the same name, on view at the J. Paul Getty Museum from February 4 to ...

The term "false memories" has been used to refer to suggestibility experiments in which whole events are apparently confabulated and in media accounts of contested memories of childhood abuse. Since 1992 psychologists have increasingly used the term "false memory" when discussing memory errors for details, such as specific words within word lists. Use of the term to refer to errors in details is a shift in language away from other terms used historically (e.g., "memory intrusions"). We empirically examine this shift (...) in language and discuss implications of the new use of the term "false memories." Use of the term presents serious ethical challenges to the data-interpretation process by encouraging over-generalization and misapplication of research findings on word memory to social issues. (shrink)

Although at times criticized for its philosophical density, French cultural theory remains a flourishing, if highly contested, area of academic study. Four feminist thinkers in this tradition continue to be especially prominent: Simone de Beauvoir, Julia Kristeva, Hélène Cixous, and Luce Irigaray. This new collection from Routledge gathers together the very best secondary literature on these thinkers to provide an indispensable conspectus of their works. Each of the four thinkers is represented by an individual volume, and each volume includes a (...) newly written introduction to that thinker’s work and her philosophical relevance. (shrink)

A recent article in this journal described practical and conceptual difficulties faced by public health researchers studying scabies outbreaks in British residential care facilities. Their study population was elderly, decisionally incapacitated residents, many of whom lacked a legally appropriate decision-maker for healthcare decisions. The researchers reported difficulties securing Research Ethics Committee approval. As practicing healthcare ethicists working in a large Canadian research hospital, we are familiar with this challenge and welcomed the authors’ invitation to join the discussion of the ‘outstanding (...) ambiguities and further questions’ that their experience uncovered. We propose a Power of Attorney for Research as one substantive solution to help address the problems they identified. Although we acknowledge the familiar shortcomings associated with Advance Directives in the clinical context, we believe that Powers of Attorney for Research Participation, accompanied by Advance Research Directives, may increase the likelihood of gaining deeper understandings of potential participant’s values and priorities and how they might apply to foreseeable research opportunities. (shrink)

Interoception can be broadly defined as the sense of signals originating within the body. As such, interoception is critical for our sense of embodiment, motivation, and well-being. And yet, despite its importance, interoception remains poorly understood within modern science. This paper reviews interdisciplinary perspectives on interoception, with the goal of presenting a unified perspective from diverse fields such as neuroscience, clinical practice, and contemplative studies. It is hoped that this integrative effort will advance our understanding of how interoception determines well-being, (...) and identify the central challenges to such understanding. To this end, we introduce an expanded taxonomy of interoceptive processes, arguing that many of these processes can be understood through an emerging predictive coding model for mind–body integration. The model, which describes the tension between expected and felt body sensation, parallels contemplative theories, and implicates interoception in a variety of affective and psychosomatic disorders. We conclude that maladaptive construal of bodily sensations may lie at the heart of many contemporary maladies, and that contemplative practices may attenuate these interpretative biases, restoring a person’s sense of presence and agency in the world. (shrink)

The current view of theoretical statements in science is that they should be literal and precise; ambiguous and metaphorical statements are useful only as pre-theoretical, exegetical, and heuristic devices and as pedagogical tools. In this paper we argue that this view is mistaken. Literal, precise statements apply to those experiential phenomena which can be defined either conventionally by criterial attribution or by internal atomic constitution. Experiential phenomena which are defined relationally and/or functionally, like nursing, in virtue of their nature, require (...) metaphorical description and explanation. In such cases, metaphor is theory-constitutive. Using insights from the philosophies of language and mind, and examples from nursing practice, education, and our own empirical research, we explore the nature of metaphor and its role in theory constitution. We argue that the apparent resistance of certain experiential phenomena to literal description and explanation is not necessarily indicative of pre-theoretic linguistic imprecision. We suggest, rather, that such resistance provides useful insights into the nature of such experiential phenomena. We also suggest that the aim of scientific theory should be methodological or epistemological precision and not merely linguistic precision. (shrink)

Recently, we reported that melanoma risk in redheads is linked not only to pale skin, but also to the synthesis of the pigment – called pheomelanin – that gives red hair its color. We demonstrated that pheomelanin synthesis is associated with increased oxidative stress in the skin, yet we have not uncovered the chemical pathway between the molecule pheomelanin and the DNA damage that drives melanoma formation. Here, we hypothesize two possible pathways. On one hand, pheomelanin might generate reactive oxygen (...) species (ROS) that directly or indirectly cause oxidative DNA damage. On the other hand, pheomelanin synthesis might consume cellular antioxidant stores and make the cell nucleus more vulnerable to other endogenous ROS. Uncovering the mechanistic pathway between pheomelanin and oxidative DNA damage will be an important step in developing strategies to lower melanoma risk in redheads. (shrink)