The existence of an unaware psychic space that influences the way we think, perceive, and decide has been known for over a century. This space, defined by Freud as the “unconscious,” contains in it...

For the epic journey of autumn migration, long-distance migratory birds use innate and learned information and follow strict schedules imposed by genetic and epigenetic mechanisms, the details of which remain largely unknown. In addition, bird migration requires integrated action of different multisensory systems for learning and memory, and the hippocampus appears to be the integration center for this task. In previous studies we found that contrasting long-distance migratory flights differentially affected the morphological complexity of two types of hippocampus astrocytes. Recently, (...) a significant association was found between the latitude of the reproductive site and the size of the ADCYAP1 allele in long distance migratory birds. We tested for correlations between astrocyte morphological complexity, migratory distances, and size of the ADCYAP1 allele in three long-distance migrant species of shorebird and one non-migrant. Significant differences among species were found in the number and morphological complexity of the astrocytes, as well as in the size of the microsatellites of the ADCYAP1 gene. We found significant associations between the size of the ADCYAP1 microsatellites, the migratory distances, and the degree of morphological complexity of the astrocytes. We suggest that associations between astrocyte number and morphological complexity, ADCYAP1 microsatellite size, and migratory behavior may be part of the adaptive response to the migratory process of shorebirds. (shrink)

The DNA in human cells is continuously undergoing damage as consequences of both endogenous processes and exposure to exogenous agents. The resulting structural changes can be repaired by a number of systems that function to preserve genome integrity. Most pathways are multicomponent, involving incision in the damaged DNA strand and resynthesis using the undamaged strand as a template. In contrast, O6-alkylguanine-DNA alkyltransferase is able to act as a single protein that reverses specific types of alkylation damage simply by removing the (...) offending alkyl group, which becomes covalently attached to the protein and inactivates it. The types of damage that ATase repairs are potentially toxic, mutagenic, recombinogenic and clastogenic. They are generated by certain classes of carcinogenic and chemotherapeutic alkylating agents. There is consequently a great deal of interest in this repair system in relation to both carcinogenesis and cancer chemotherapy. BioEssays 24:255–266, 2002. © 2002 Wiley Periodicals, Inc.; DOI 10.1002/bies.10063. (shrink)

This paper argues that Deonna and Teroni's attitudinal theory of emotions faces two serious problems. The first is that their master argument fails to establish the central tenet of the theory, namely, that the formal objects of emotions do not feature in the content of emotions. The second is that the attitudinal theory itself is vulnerable to a dilemma. By pointing out these problems, our paper provides indirect support to the main competitor of the attitudinal theory, namely, the perceptual theory (...) of emotions. (shrink)

Highlights Merleau-Ponty’s interest in film and connects it to his aesthetic theory.

In this paper, we review and connect the three essential conditions needed by the collapse model to achieve a complete and exact formulation, namely the theoretical, the experimental, and the ontological ones. These features correspond to the three parts of the paper. In any empirical science, the first two features are obviously connected but, as is well known, among the different formulations and interpretations of non-relativistic quantum mechanics, only collapse models, as the paper well illustrates with a richness of details, (...) have experimental consequences. Finally, we show that a clarification of the ontological intimations of collapse models is needed for at least three reasons: (1) to respond to the indispensable task of answering the question ’what are collapse models (and in general any physical theory) about?’; (2) to achieve a deeper understanding of their different formulations; (3) to enlarge the panorama of possible readings of a theory, which historically has often played a fundamental heuristic role. (shrink)

The goal of this paper is to offer a new theory of moods, according to which moods are perceptual experiences that represent undetermined objects as possessing specific evaluative properties. I start by listing a series of features that moods are typically taken to possess and claim that a satisfactory theory of moods must be able either to explain why moods genuinely possess these features or to explain these appearances away in a non-ad hoc way. I show that my account provides (...) a plausible explanation of all the main features of moods. I conclude by addressing some objections against my account. (shrink)

In line with earlier works, this article argues for a “continuist” interpretation of Brentano’s conception of intentionality. It maintains that Brentano’s conception of intentionality rests on a complex set of notions, which are reduced to a minimal core or applied more fully depending on the complexity of the mental phenomenon under consideration and perspective from which it is analyzed. The article positions this conceptual structure in relation to theories of objects developed within the framework of late- and Neo-Scholastic philosophy where, (...) since the psychic act can relate to its object in different ways, the different types and roles of objects must be distinguished. This theory of objects enables Brentano to reinterpret Aristoteles’s idea of the intentionality of mental phenomena in light of the commentaries and interpretations of Thomas Aquinas while also giving space to other medieval texts. (shrink)

In this paper, we propose a defence of Value Realism that relies on the unusual combination of Values Realism with Sentimentalism. What this account, which we call “Sentimental Realism”, holds, in a nutshell, is that what makes evaluative facts special is their relationship to emotions. More precisely, Sentimental Realism claims that evaluative facts are fully objective facts, but that such facts are picked out by concepts that are response-dependent, in the sense that they are essentially tied to emotions. Our plan (...) is as follows. We shall start with a presentation of Sentimental Realism and a discussion of its main virtues. On the basis of this, we shall discuss an objection to Value Realism that draws on evolutionary considerations, the Evolutionary Debunking Argument. We shall argue that Sentimental Realism safely escapes from this dilemma. (shrink)

Mauro Dorato charts pressing debates within the philosophy of science that centre around scientific expertise, access to knowledge, consensus, debate, and decision-making. This English-language translation of Disinformazione Scientifica e Democrazia argues that the advancement of science depends on an exponential process of specialization, accompanied by the creation of technical languages that are less and less accessible to the general public. Dorato reveals how such a process must align with representative forms of democracies, in which knowledge and decision-making ought to (...) aim at the society's general interest. Given the importance of the principle of competence, however, the role of experts as mediators of knowledge threatens the citizens' autonomy of choice. Consequently, the risk of technocratic regimes calls for new ways to increase literacy about science and its philosophical and probabilistic foundations. Stressing the conceptual conflict between pluralism and conformism, Science and Representative Democracyreveals the obstacles to the functioning of both science and democracy. (shrink)

What is the relation between virtue and wellbeing? Our claim is that, under certain conditions, virtue necessarily tends to have a positive impact on an individual’s wellbeing. This is so because of the connection between virtue and psychological happiness, on the one hand, and between psychological happiness and wellbeing, on the other hand. In particular we defend three claims: that virtue is constituted by a disposition to experience fitting emotions, that fitting emotions are constituents of fitting happiness, and that fitting (...) happiness is a constituent of wellbeing. What follows is that, under certain conditions, virtue disposes the individual to experience wellbeing-constituting states. We end with a discussion of two objections that may be raised against our proposal. (shrink)

We discuss the three dominant models of the phenomenological literature pertaining to temporal consciousness, namely the cinematic, the retentional, and the extensional model. This is first done by presenting the distinction between acts and contents of consciousness and the assumptions underlying the different models concerning both the extendedness and duration of these two components. Secondly, we elaborate on the consequences related to whether a perspective of direct or indirect realism about temporal perceptions is assumed. Finally, we review some relevant findings (...) from the psychology and neuroscience of temporality in order to decide which of the three models of time consciousness is better confirmed from an empirical viewpoint. Depending on the time scale, all three models of temporal consciousness might apply. We specifically argue in favor of an extensional model of time consciousness for the experienced present where the acts and contents of consciousness are both extended. The retentional model might apply to longer time intervals covered by working memory. In addition, a predictive component is highlighted as decisive for an understanding of temporality. (shrink)

In this paper, we evaluate some proposals that have been put forward to clarify the ontological consequences of relational quantum mechanics. We first focus on priority monism and ontic structural realism and argue that these views are not suitable for providing an ontological interpretation of the theory. Then, we discuss an alternative interpretation that we regard as more promising, based on so-called ‘metaphysical coherentism’, which we also connect to the idea of an event-based, or ‘flash’, ontology.

Mechanisms are a way of explaining how biological phenomena work rather than why single elements of biological systems are there. However, mechanisms are usually described as physiological entities, and little or no attention is paid to malfunction as an independent theoretical concept. On the other hand, malfunction is the main focus of interest of applied sciences such as medicine. In this paper I argue that malfunctions are parts of pathological mechanisms, which should be considered separate theoretical entities, conceptually having a (...) priority over physiological sequences. While pathological mechanisms can be described in terms of a Cummins-like mechanistic explanation, they show some unnoticed peculiarities when compared to physiological ones. Some features of pathological mechanisms are considered, such as outcome variability, ambivalence and dependence on a range. (shrink)

In this paper, I pursue two main goals. The first is to raise three objections against Tom Roberts and Joel Krueger’s recent account of loneliness (2021). The second is to sketch an alternative, receptive account. Roberts and Krueger focus on loneliness conceived of as an occurrent emotion. According to their account, loneliness involves two components: (1) a pro-attitude (e.g., a desire) towards certain social goods and (2) an awareness that such goods “are missing and out of reach, either temporarily or (...) permanently” (p. 186). My first objection is that having a pair of pro-attitudes and cognitive states of the sort that Roberts and Krueger have in mind is neither sufficient nor necessary for an individual to experience loneliness. The second is that Roberts and Krueger’s account has trouble accounting for the unpleasant phenomenology of loneliness. The third is that their account has trouble demarcating loneliness from other negative emotions that one may experience within romantic, friendship or social relationships. Next, I sketch my own account of loneliness. According to the receptive theory (Tappolet 2022) to which I adhere, emotions are receptive experiences that non-conceptually represent their intentional objects as possessing specific evaluative properties. Accordingly, I argue that loneliness consists in a receptive experience that represents the absence of certain relational goods as bad in a particular way. I draw a distinction between the intentional object and the intentional locus of loneliness, and clarify the role that some of the individual’s pro-attitudes play in loneliness. I also show how a receptive account can explain the phenomenology of loneliness and demarcate it from other emotion types, and offer an account of degrees of loneliness, which distinguishes between the intensity and the centrality of episodes of loneliness. (shrink)

In this paper I present and defend Rovelli's relation quantum mechanics from some foreseeable objections, so as to clarify its philosophical implications vis a vis rival interpretations. In particular I will ask whether RQM presupposes a hidden recourse to both a duality of evolutions and of ontology. I then concentrate on the pluralistic, antimonistic metaphysical consequences of the theory, due to the impossibility of assigning a state to the quantum universe. Finally, in the last section I note interesting consequences of (...) RQM with respect to the possibility of defining a local, quantum relativistic becoming.Given the difficulties of having the cosmic form of becoming that would be appropriate for priority monism, RQM seems to present an important advantage with respect to monistic views, at least insofar as far as the possibility of explaining our experience of time is concerned. (shrink)

The literature on the compatibility between the time of our experience--characterized by passage or becoming--and time as is represented within spacetime theories has been affected by a persistent failure to get a clear grasp of the notion of becoming, both in its relation to an ontology of events tt"spreadtt" in a four-dimensional manifold, and in relation to temporally asymmetric physical processes.In the first part of my paper I try to remedy this situation by offering what I consider a clear and (...) faithful explication of becoming, valid independently of the particular spacetime setting in which we operate. Along the way, I will show why the metaphysical debate between the so-called tt"presentiststt" and tt"eternaliststt" is completely irrelevant to the question of becoming, as the debate itself is generated by a failure to distinguish between a tensed and a tenseless sense of tt"existencett". After a much needed distinction between absolute and relational becoming, I then show in what sense classical spacetime physics presupposes both types of becoming, for the simple reason that spacetime physics presupposes an ontology of events. As a consequence, not only does it turn out that using physics to try to provide empirical evidence for the existence of becoming amounts to putting the cart before the horses, but also that the order imposed by tt"the arrow of becomingtt" is more fundamental than any other physical arrow of time, despite the fact that becoming cannot be used to explain why entropy grows, or retarded electromagnetic radiation prevails versus advanced radiation. (shrink)

I temi della corporeità, della sporcizia, della materialità, in una ricerca esasperata di realismo.

In the literature on the compatibility between the time of our experience and the time of physics, the special theory of relativity has enjoyed central stage. By bringing into the discussion the general theory of relativity, I suggest a new analysis of the misunderstood notion of becoming, developed from hints in Gödel's published and unpublished arguments for the ideality of time. I claim that recent endorsements of such arguments, based on Gödel's own ‘rotating’ solution to Einstein's field equation, fail: once (...) understood in the right way, becoming can be shown to be both mind-independent and compatible with spacetime physics. Being a neededtertium quidbetween views of time traditionally regarded as in conflict, such a new approach to becoming should also help to dissolve a crucial aspect of the century-old debate between the so-called A and B theories of time. (shrink)

In The Pursuit of Unhappiness, Daniel Haybron has defended an emotional state theory of happiness, according to which happiness consists in a broadly positive balance of emotions, moods, and mood propensities. In this paper, I argue that Haybron’s theory should be modified in two ways. First, contra Haybron, I argue that sensory pleasures should be regarded as constituents of happiness, alongside emotions and moods. I do this by showing that sensory pleasures are sufficiently similar to emotions for them to be (...) included within the class of happiness-constituting states. Second, I argue that a plausible theory of happiness should not include mood propensities, since their inclusion is either counterintuitive or unnecessary. (shrink)

Using an original approach, Mauro Dardo recounts the major achievements of twentieth-century physics--including relativity, quantum mechanics, atomic and nuclear physics, the invention of the transistor and the laser, superconductivity, binary pulsars, and the Bose-Einstein condensate--as each emerged. His year-by-year chronicle, biographies and revealing personal anecdotes help bring to life the main events since the first Nobel Prize was awarded in 1901. The work of the most famous physicists of the twentieth century--including the Curies, Bohr, Heisenberg, Einstein, Fermi, Feynman, Gell-Mann, (...) Rutherford, and Schrödinger--is presented, often in the words and imagery of the prize-winners themselves. Mauro Dardo is Professor of Experimental Physics at Amedeo Avogadro University. He has served as Dean of the new Faculty of Sciences at the University of Turin in Alessandria, Piedmont, and has also served as Director of the university's new department of Sciences and Advanced Technologies. (shrink)

In this paper we argue that quantum mechanics provides a genuine kind of structural explanations of quantum phenomena. Since structural explanations only rely on the formal properties of the theory, they have the advantage of being independent of interpretative questions. As such, they can be used to claim that, even in the current absence of one agreed-upon interpretation, quantum mechanics is capable of providing satisfactory explanations of physical phenomena. While our proposal clearly cannot be taken to solve all interpretive issues (...) raised by quantum theory, we will argue that it can be successfully applied to some of its most puzzling phenomena, such Heisenberg's uncertainty relations and quantum non-locality. The discussion of these two case studies will also serve to illustrate the main properties of structural explanations and compare them to the DN and the unificationist models. Finally, we briefly discuss how structural explanations might relate to structural realism. (shrink)

In his recently published seminar Life Death (1975–76), Derrida engages in a close reading of Heidegger's refutation of the biologistic interpretation of Nietzsche. Derrida explains that, building on his interpretation of Nietzsche as the peak of metaphysics, Heidegger wishes to rescue the latter's metaphysical discourse from its biologizing character. In this article, I argue that Derrida's reading centres on the ontological regionalism undergirding Heidegger's refutation. To develop this argument, I test the following three hypotheses. First, I show that the later (...) exploration offered in Life Death draws on the schematic reading of Heidegger's question of being provided in Of Grammatology (1967). Second, I explain that, for Derrida, through his refutation of Nietzsche's supposed biologism, Heidegger reaffirms ontological regionalism in order to secure the whole interpretative system that interweaves together his reading of Nietzsche and Western metaphysics and his thinking of being. Finally, I highlight Derrida's emphasis on the relentlessness of Heidegger's denunciation of biologism. I demonstrate that, for Derrida, this can be explained as biology, which is a discourse on life and nature that since its beginnings touches on the blind point of regionalism. (shrink)

Comment pouvons-nous analyser des relations de valeur non standards, comme la parité axiologique, en termes d’attitudes appropriées? Wlodek Rabinowicz suggère que deux choses sont à parité si et seulement si il est à la fois permissible de préférer l’une à l’autre et permissible d’avoir la préférence contraire. Dans un article récent, Johan Gustafsson soutient toutefois que l’analyse de Rabinowicz viole un principe de symétrie entre valeurs et préférences, selon lequel il existe pour toute relation de valeur une relation de préférence (...) correspondante (et vice-versa). À la lumière de ce principe, Gustafsson propose une analyse alternative, selon laquelle deux choses sont à parité si et seulement si il est requis d’entretenir ces choses en parité préférentielle. Dans cet article, j’examine en détail les arguments avancés par Gustafsson contre l’analyse de Rabinowicz et je montre qu’aucun d’eux n’est convaincant. (shrink)