Fahr’s disease is a rare idiopathic degenerative disease characterized by calcifications in the brain, and has also been associated with balance impairment. However, a detailed analysis of balance in these patients has not been performed. A 69-year-old woman with Fahr’s disease presented with a long-lasting subjective imbalance. Balance was analyzed using both clinical and instrumented tests. The patient’s balance was normal during clinical tests and walking. However, during standing, a striking impairment in vestibular control of balance emerged. The balance behavior (...) displayed mixed parkinsonian and cerebellar features, with a discrepancy between the high severity of the static and the low severity of the dynamic balance impairment. The balance impairment characteristics outlined in this study could help neurologists and physiatrists detect, stage, and treat this rare condition. (shrink)

The potential to collect brain data more directly, with higher resolution, and in greater amounts has heightened worries about mental and brain privacy. In order to manage the risks to individuals posed by these privacy challenges, some have suggested codifying new privacy rights, including a right to “mental privacy.” In this paper, we consider these arguments and conclude that while neurotechnologies do raise significant privacy concerns, such concerns are—at least for now—no different from those raised by other well-understood data collection (...) technologies, such as gene sequencing tools and online surveillance. To better understand the privacy stakes of brain data, we suggest the use of a conceptual framework from information ethics, Helen Nissenbaum’s “contextual integrity” theory. To illustrate the importance of context, we examine neurotechnologies and the information flows they produce in three familiar contexts—healthcare and medical research, criminal justice, and consumer marketing. We argue that by emphasizing what is distinct about brain privacy issues, rather than what they share with other data privacy concerns, risks weakening broader efforts to enact more robust privacy law and policy. (shrink)

Over the last five decades, philosophers of language have looked into the mechanisms for doing things with words. The same attention has not been devoted to how to undo those things, once they have been done. This paper identifies and examines three strategies to make one’s speech acts undone—namely, Annulment, Retraction, and Amendment. In annulling an act, a speaker brings to light its fatal flaws. Annulment amounts to recognizing an act as null, whereas retraction and amendment amount to making it (...) null. Speakers employ retraction to cancel the deontic updates engendered by a given act. They instead use amendment to adjust its degree of strength. I will argue that annulling, retracting, and amending are second-order speech acts, whose felicity conditions vary with the type of illocution they operate on. Undoing is therefore conceived of as a form of doing. Furthermore, I claim that, in calling off our acts, we undo the conventional or illocutionary effects of our words while leaving intact their past causal or perlocutionary outcomes. (shrink)

Bringing together Luce Irigaray's early psychoanalytically orientated writings with her more recent and more explicitly political writings, Irigaray and Politics weaves together the ontological, political and ethical dimensions of Irigaray's philosophy of sexuate difference in imaginative ways.

Is religious faith consistent with being an intellectually virtuous thinker? In seeking to answer this question, one quickly finds others, each of which has been the focus of recent renewed attention by epistemologists: What is it to be an intellectually virtuous thinker? Must all reasonable belief be grounded in public evidence? Under what circumstances is a person rationally justified in believing something on trust, on the testimony of another, or because of the conclusions drawn by an intellectual authority? Can it (...) be reasonable to hold a belief on a topic over which there is significant, entrenched disagreement among informed inquirers, or should such disagreement lead all parties to modify or suspend their own judgments? Is there anything about faith that exempts it from measurement against such epistemic norms? And if we would so evaluate it, how exactly should we understand the intellectual commitments faith requires? The volume's introduction provides a roadmap of the central issues and controversies as currently discussed by philosophers. In fourteen new essays written to engage nonspecialists as well as philosophers working in religion and epistemology, a diverse and distinguished group of thinkers then consider the place of intellectual virtue in religious faith, exploring one or more of the specific issues noted above. (shrink)

One realist response to the pessimistic meta-induction distinguishes idle theoretical wheels from aspects of successful theories we can expect to persist and espouses realism about the latter. Implementing the response requires a strategy for identifying the distinguished aspects. The strategy I will call renormalization group realism has the virtue of directly engaging the gears of our best current physics—perturbative quantum field theories. I argue that the strategy, rather than disarming the skeptical possibilities evinced by the pessimistic meta-induction, forces them to (...) retreat a level. I also suggest that those skeptical possibilities continue to carry force. (shrink)

The ambiguity regarding whether a given intervention is perceived as enhancement or as therapy might contribute to the angst that the public expresses with respect to endorsement of enhancement. We set out to develop empirical data that explored this. We used Amazon Mechanical Turk to recruit participants from Canada and the United States. Each individual was randomly assigned to read one vignette describing the use of a pill to enhance one of 12 cognitive, affective or social domains. The vignettes described (...) a situation in which an individual was using a pill to enhance the relevant domain under one of two possible enhancement conditions, one perceived as enhancing above the norm, what most people recognize as a clear case of enhancement, whereas the other perceived as enhancing towards the norm, with the individual using the enhancement having a modest, but subclinical deficit. Participants were asked how comfortable they were with the individual using the enhancement and about the impact the enhancement might have had in the individuals’ success in life. We found that irrespective of the domain to be enhanced, participants felt significantly more comfortable with ETN than with EAN, and they regarded the enhancement intervention as contributing to greater success in life with ETN rather than EAN. These data demonstrate that the therapy enhancement distinction is morally salient to the public, and that this distinction contributes to the angst that people feel when considering the propriety of CAS enhancement. (shrink)

Taking Arthur Fine’s The Shaky Game as my inspiration, and the recent 25th anniversary of the publication of that work as the occasion to exercise that inspiration, I sketch an alternative to the “Naturalism” prevalent among philosophers of physics. Naturalism is a methodology eventuating in a metaphysics. The methodology is to seek the deep framework assumptions that make the best sense of science; the metaphysics is furnished by those assumptions and supported by their own support of science. The alternative presented (...) here, which I call “Locavoracity,” shares Naturalism’s commitment to making sense of science, but alters Naturalism’s methodology. The Locavore’s sense-making projects are piecemeal, rather than sweeping. The Locavore’s hypothesis is that the collection of local sense-making projects fails to issue a single overarching unifying framework deserving of the title “the metaphysics that makes the best sense of science.” I muster some examples supporting the Locavore hypothesis from the interpretation of quantum field theories. (shrink)

Scientists typically use a variety of representations, including different kinds of figures, to present and defend hypotheses. In order to understand the justification of scientific hypotheses, it is essential to understand how visual representations contribute to scientific arguments. Since the logical understanding of arguments involves the truth or falsity of the representations involved, visual representations must have the capacity to bear truth in order to be genuine components of arguments. By drawing on Goodman's analysis of symbol systems, and on Tarski's (...) work on truth, I show that the figures used in science meet this criterion. (shrink)

The debate over the propriety of cognitive enhancement evokes both enthusiasm and worry. To gain further insight into the reasons that people may have for endorsing or eschewing pharmacological enhancement, we used empirical tools to explore public attitudes towards PE of twelve cognitive, affective, and social domains. Participants from Canada and the United States were recruited using Mechanical Turk and were randomly assigned to read one vignette that described an individual who uses a pill to enhance a single domain. After (...) reading the vignette, participants were asked how comfortable they were with the individual using the enhancement. People were significantly more comfortable when they read about enhancement of certain CAS domains than others. We found a modest negative correlation between comfort level and the degree to which the PE was perceived as changing core features of the person. We also found a modest correlation between comfort level and the degree to which the PE was perceived as improving success in life. Finally, using a sequential mixed method technique, we found that participants who felt uncomfortable about PE use overwhelmingly focused on a lack of need and, to a lesser degree, expressed concerns about safety; those who felt comfortable about PE use most frequently mentioned the safety of the pill and its ability to provide a positive outcome. The data provide novel insights into public enthusiasms and concerns over the use of PE. (shrink)

The aim of this paper is to analyse the role that the distinction between principle and constructive theories have in the question of the explanatory power of Special Relativity. We show how the distinction breaks down at the explanatory level. We assess Harvey Brown’s (2005) claim that, as a principle theory, Special Relativity lacks of explanatory power and criticize it, as, we argue, based upon an unrealistic picture of the kind of explanations provided by principle (and constructive) theories. Finally, we (...) claim that the structural account of explanation (Hughes 1989b) captures the explanatory success of Special Relativity. (shrink)

Moorean constructions are famously odd: it is infelicitous to deny that you believe what you claim to be true. But what about claiming that p, only to immediately put into question your evidence in support of p? In this paper, we identify and analyse a class of quasi-Moorean constructions, which we label counterevidentials. Although odd, counterevidentials can be accommodated as felicitous attempts to mitigate one’s claim right after making it. We explore how counterevidentials differ from lexicalised mitigation operators, parentheticals, and (...) anaphoric mitigation devices, and consider some cognate non-assertoric constructions. We conclude by exploring the implications of our analysis for theorising about linguistic responsibility, assertion, and lying. (shrink)

This paper sketches a right-maker account of normative practical reasons along functionalist lines. The approach is contrasted with other similar accounts, in particular John Broome's analysis of reasons as explanations of oughts.

This paper sets out to unpack the pragmatic structure of refusal—its illocutionary nature, success conditions, and normative effects. I argue that our ordinary concept of refusal captures a whole family of illocutions, comprising acts such as rejecting, declining, and the like, which share the property of being ‘negative second-turn illocutions’. Only _proper refusals_ (i.e. negative replies to permission requests), I submit, require speaker authority. I construe the ‘refusal family’ as a subclass of the directives-commissives intersection. After defending my view against (...) a number of potential objections, I highlight how a theoretically grounded analysis of refusal is not only of intrinsic value, but may also have significant moral and legal implications. (shrink)

Context: I extend the enactive account of loving in romantic relationships that I developed with Hanne De Jaegher to the love of nature. Problem: I challenge a universal conceptualization of love of nature that does not account for the differences that are inherent to nature. As an alternative, I offer a situated account of loving a place as participatory sense-making. However, a question arises: How is it possible to communicate with the other-than-human? Method: I use panpsychist and enactive conceptual tools (...) to better define this situated approach to the love of nature and to reply to the research question. In particular, I focus on Mathews’s “becoming native” and the generative tensions that unfold in a dialectic of encounter when a common language is not shared. Results: The fundamental difference experienced in encountering the other-than-human is generative for building up the human-Earth connection if we let each other be listened to. I describe the ethical dimension that permeates this type of “enactive listening” at the core of a situated account of love of nature. Implications: Love of nature is of paramount importance in our current climate crisis characterized by environmental anxiety, despair, and anger. A situated love of nature emphasizes the importance of community-based local interventions to preserve the Earth. Love, thus understood as a fundamental moral and political power, is a catalyst for environmental activism. Constructivist content: My article links to participatory sense-making as defined by De Jaegher and Di Paolo, and De Jaegher’s loving epistemology. It offers a broader understanding of participatory sense-making that includes the other-than-human. It also introduces the new concept of “enactive listening.”. (shrink)

This article documents our collaborative ongoing struggle to disrupt the reproduction of the coloniality of knowledge in the teaching of Gender Studies. We document how our decolonial feminist activism is actualised in our pedagogy, which is guided by feminist interpretations of ‘wonder’ (Irigaray, 1999; Ahmed, 2004; hooks, 2010) read alongside decolonial theory, including that of Ramón Grosfoguel, Walter D. Mignolo and María Lugones. Using notions of wonder as pedagogy, we attempt to create spaces in our classrooms where critical self-reflection and (...) critical intellectual and embodied engagement can emerge. Our attempts to create these spaces include multiple aspects or threads that, when woven together, might enable other ways of knowing-being-doing that works towards disrupting feminist complicity with coloniality in the Australian context. (shrink)

Publications in contemporary science journals often include figures like graphs, diagrams, photographs, and MRIs, which are presented as support for the hypothesis the author is defending. As a first step to explaining how figures contribute to confirmation, I present an account of visual representation and use examples to show how the visual format is involved in the support those figures provide the authors’ conclusions. I then show that attempts to explain what figures contribute to scientific arguments without analyzing them as (...) visual representations will not succeed. (shrink)

Starting from the standard quantum formalism for a single spin 1/2 system (e.g., an electron), this essay develops a model rich enough not only to afford an explication of symmetry breaking but also to frame questions about how to circumscribe physical possibility on behalf of theories that countenance symmetry breaking.

A normal state on a von Neumann algebra defines a countably additive probability measure over its projection lattice. The von Neumann algebras familiar from ordinary QM are algebras of all the bounded operators on a Hilbert space H, aka Type I factor von Neumann algebras. Their normal states are density operator states, and can be pure or mixed. In QFT and the thermodynamic limit of QSM, von Neumann algebras of more exotic types abound. Type III von Neumann algebras, for instance, (...) have no pure normal states; the pure states they do have fail to be countably additive. I will catalog a number of temptations to accord physical significance to non-normal states, and then give some reasons to resist these temptations: pure though they may be, non-normal states on non-Type I factor von Neumann algebras can't do the interpretive work we've come to expect from pure states on Type I factors; our best accounts of state preparation don't work for the preparation of non-normal states; there is a sense in which non-normal states fail to instantiate the laws of quantum mechanics. (shrink)

Emotions ( pathè) such as anger, fear, shame, and envy, but also pity, wonder, love and friendship have long been underestimated in Plato’s philosophy. The aim of Emotions in Plato is to provide a consistent account of the role of emotions in Plato’s psychology, epistemology, ethics and political theory. The volume focuses on three main issues: taxonomy of emotions, their epistemic status, and their relevance for the ethical and political theory and practice. This volume, which is the first edited volume (...) entirely dedicated to emotions in Plato’s philosophy, shows how Plato, in many aspects, was positively interested in these affective states in order to support the rule of reason. (shrink)

The need to evaluate the performance of clinical ethics services is widely acknowledged although work in this area is more developed in the United States. In the USA many studies that assess clinical ethics services have utilized empirical methods and assessment criteria. The value of these approaches is thought to rest on their ability to measure the value of services in a demonstrable fashion. However, empirical measures tend to lack ethical content, making their contribution to developments in ethical governance unclear. (...) The steady increase of clinical ethics committees in the UK must be accompanied by efforts to evaluate their performance. As part of this evaluative work it is important to examine how the practice of clinical ethics committees can be informed by empirical measures. (shrink)

Background: The concept of dignity can be divided into two main attributes: absolute dignity that calls for recognition of an inner worth of persons and social dignity that can be changeable and can be lost as a result of different social factors and moral behaviours. In this light, the nursing profession has a professional dignity that is to be continually constructed and re-constructed and involves both main attributes of dignity. Objectives: The purpose of this study was to determine how nurses (...) described nursing’s professional dignity in internal medicine and surgery departments in hospital settings. Research design: The research design was qualitative. Ethical considerations: This study was approved by the ethics committees of the healthcare organizations involved. All the participants were provided with information about the purpose and the nature of the study. Participants: A total of 124 nurses participated in this study. Method: The data were collected using 20 focus group sessions in different parts of Italy. The data were analysed by means of a conventional inductive content analysis starting from the information retrieved in order to extract meaning units and sorting the arising phenomena into conceptually meaningful categories and themes. Results: Nursing’s professional dignity was deeply embedded in the innermost part of individuals. Regarding the social part of dignity, a great importance was put on the values that compose nursing’s professional identity, the socio-historical background and the evolution of nursing in the area considered. The social part of dignity was also linked to collaboration with physicians and with healthcare assistants who were thought to have a central role in easing work strain. Equally important, though, was the relationship with peers and senior nurses. Conclusion: The organizational environments under scrutiny with their low staffing levels, overload of work and hierarchical interactions did not promote respect for the dignity of nurses. To understand these professional values, it is pivotal to comprehend the role of different health professions in their cultural milieu and the evolution of the nursing profession in diverse countries. (shrink)

This book provides rigorous analyses of Deleuze's writings on theatre practitioners such as Artaud, Beckett and Carmelo Bene, as well as offering innovative ...

In recent years, discussion around memory modification interventions has gained attention. However, discussion around the use of memory interventions in the criminal justice system has been mostly absent. In this paper we start by highlighting the importance memory has for human well-being and personal identity, as well as its role within the criminal forensic setting; in particular, for claiming and accepting legal responsibility, for moral learning, and for retribution. We provide examples of memory interventions that are currently available for medical (...) purposes, but that in the future could be used in the forensic setting to modify criminal offenders’ memories. In this section we contrast the cases of dampening and enhancing memories of criminal offenders. We then present from a pragmatic approach some pressing ethical issues associated with these types of memory interventions. The paper ends up highlighting how these pragmatic considerations can help establish ethically justified criteria regarding the possibility of interventions aimed at modifying criminal offenders’ memories. (shrink)

In this paper, we argue that the intentionality at play in skilled performance is not only inherently normative but also inherently affective. We take a radically embodied approach to the mind in which we conceive of cognitive agents as sensorimotor systems moved to maintain their biological and sociocultural identity, whose perception is direct and occurs in terms of affordances. Within this framework, we define skilled performance as the enactment of action and perception patterns in which the agent is intentionally oriented (...) towards specific features in the environment. We propose that skillful intentionality is guided by normative constraints involving the material and social conditions of the agent but is ultimately determined by the intrinsic purpose of maintaining the agent’s identity, and skilled intentionality is inherently affective because it is a specific occurrence arising from a general sense of care to maintain one’s identity which is realized by orienting oneself towards the right aspects of the environment in the right way. Skilled performance thus requires agents to establish a normative and affective intentionality towards aspects of their material environment. We show that, since sociocultural practices shape human identities, sociocultural practices play a crucial role in shaping human intentionality of skilled performance both in their normative and affective dimensions. Maintaining a human identity, we argue, amounts to routinely carrying out activities that form a historical pattern which is shared with and recognized by others. (shrink)

Zusammenfassung Hintergrund Stigmatisierung hat einen erheblichen Einfluss auf die Gesundheit verschiedener gesellschaftlicher Gruppen und trägt zu Ungleichheiten im Gesundheitswesen bei. Sexarbeit ist mit erheblichem sozialem Stigma verbunden, das sich nachteilig auf den Zugang von Sexarbeiter*innen zur Gesundheitsversorgung auswirkt. Die vorliegende explorative Studie gibt erste Einblicke in die Sichtweisen von Sexarbeiter*innen und Berater*innen in Deutschland auf den Zugang, die Bedürfnisse und die Barrieren von Sexarbeiter*innen in Bezug auf die Gesundheitsversorgung. Dabei lag der Fokus auf einem etablierten Netzwerk von Gesundheitsangeboten für Sexarbeiter*innen (...) in Bochum. Methoden Leitfadengestützte Interviews wurden mit 4 Berater*innen durchgeführt, die soziale und medizinische Beratung für Sexarbeiter*innen anbieten, sowie mit 3 Sexarbeiter*innen, die diese Angebote nutzen. Die Interviews wurden mittels qualitativer Inhaltsanalyse nach Kuckartz ausgewertet. Ergebnisse Es zeigten sich verschiedene Hürden bei der Inanspruchnahme von Gesundheitsversorgung, insbesondere aufgrund unzureichender Krankenversicherung oder fehlendem Wissen über den eigenen Krankenversicherungsstatus, Sprachbarrieren, Bürokratie, Mobilität und Diskriminierung in der Gesundheitsversorgung. Diskriminierung aufgrund von Sexarbeit überschnitt sich mit anderen Diskriminierungsformen, wie beispielsweise antislawischem Rassismus oder der Stigmatisierung von Schwangerschaftsabbrüchen. Spezifische Bedürfnisse und Barrieren wurden hinsichtlich psychischer Gesundheit angegeben, die sich als wichtiges Thema für Sexarbeiter*innen erwies. Die bestehenden kostenlosen, anonymen und zugänglichen Angebote für Sexarbeiter*innen, insbesondere aufsuchende Angebote, wurden als hilfreich beschrieben. Sexarbeiter*innen und Berater*innen wiesen auf einen Mangel an Angeboten für unterschiedliche Bedürfnisse von Sexarbeiter*innen hin, die über Tests auf sexuell übertragbare Infektionen und deren Behandlung hinausgehen, z. B. im Bereich der psychischen Gesundheit. Schlussfolgerung Nach wie vor bestehen Barrieren für den Zugang zur Gesundheitsversorgung, von denen viele besonders Sexarbeiter*innen mit Migrationsgeschichten aus osteuropäischen Ländern betreffen. Die Studie zeigt, dass die Etablierung antidiskriminierender Gesundheitsangebote für Sexarbeiter*innen notwendig ist. Bei der Entwicklung solcher Angebote sollten die Perspektiven von Sexarbeiter*innen eine zentrale Rolle einnehmen. (shrink)

In Thinking How to Live, Allan Gibbard claims that expressivists can vindicate realism about moral discourse. This paper argues that Gibbard’s expressivism does not provide such a vindication.

Background: Psychiatric interventions are a contested area in medicine, not only because of their history of abuses, but also because their therapeutic goal is to affect emotions, thoughts, beliefs...

There has been an ongoing debate about the best approach in environmental ethics. Bryan Norton believes that “weak anthropocentrism” will yield the best results for public policy, and that it is the most defensible position. In contrast, I have argued that an ecocentric, holistic position is required to deal with the urgent environmental problems that face us, and that position is complemented by the ecosystem approach and complex systems theory. I have called this approach “the ethics of integrity,” and in (...) this paper I show why this perspective suggests better solutions to difficult cases, for which “weak anthropocentrism” fails to provide an answer. (shrink)

This paper draws on the philosophies of Maurice Merleau‐Ponty and Hannah Arendt in order to explore the nature of free action. Part one outlines three familiar ways in which we often understand the nature of freedom. Part two argues that these common understandings of freedom are rooted in impoverished conceptions of time and subjectivity. Part three engages with Arendt’s conception of natality alongside Merleau‐Ponty’s conception of expression in order to argue that the freely acting self draws in improvisational manners on (...) the resources of a shared past in order to open unprecedented spaces of meaning for the future, and in so doing at once discovers and institutes herself as the self that she is. Part four draws on an example of anti‐oppressive political action in order to argue that free action not only has the power to inaugurate new spaces of shared meaning for the future, but also to change the sens of the shared past. By the same token, free action is vulnerable in its ontological status and ethical meanings to the events and judgments of the future. Part five argues with both Merleau‐Ponty and Arendt that ethical‐political actors can do no better than to cultivate a political virtù while facing up to the inherently transgressive dimensions of free action in a shared historical world. (shrink)

This paper presents the contribution of the pragmatic sociology of critical capacities to the understanding of environmental conflicts. In the field of 'environmental valuation', nowadays colonised by economics, the approach of plural modes (or 'regimes') of engagement provides a sociological understanding of the unequal power of conflicting 'languages of valuation'. This frame entails a shift from 'values' to 'modes of valuation', and links modes of valuation to modes of practical engagement and coordination with the surrounding environment. Different social sources of (...) incommensurability are thus detected and reframed as critical tension within and among modes of human coordination with the environment. (shrink)

This paper approaches the much-debated issue of corporate citizenship (CC). Many models depict the development process of CC, and yet attempts to find one extensive definition remain in progress. We argue that more than one type of citizenship may be needed to fully describe the concept. So far, social factors have dominated the definitions of CC, but citizenship functions can also be found in other areas. In fact, for maximum benefit, the type of citizenship should be tied to the sector (...) and business field of the corporation in question. Using data drawn from three internationally operating corporations headquartered in Finland, we introduce three different types of CC that are in line with their core business ideas: cultural citizenship, environmental citizenship and technological citizenship. These new types of citizenships can help in grasping the complexity of business responsibility and ethics, and offer tools for gaining competitive advantage by differentiation. (shrink)

ABSTRACT Against empiricist and rationalist prejudices concerning the nature of issues related to “mental health,” this article offers a phenomenological account of identity as developed in a meaningful system with the environment or world. Drawing on the work of Merleau-Ponty and Dewey, I argue that behavioral and emotional health and illness must be understood in terms of the plasticity or rigidity, respectively, of the individual's responses in the face of new and threatening environmental demands. However, individual plasticity and rigidity are (...) not given qualities of the individual but are themselves developed in healthy or unhealthy interpersonal environments. I discuss three cases of emotional and behavioral trouble in order to explore the manner in which unhealthy self-environment systems can undermine individuals' powers of adaptability and growth. (shrink)

An “intrinsically mixed” state is a mixed state of a system that is ‘orthogonal’ to every pure state of that system. Although the presence of such states in the quantum theories of infinite systems is well known to those who work with such theories, intrinsically mixed states are virtually unheralded in the philosophical literature. Rob Clifton was thoroughly familiar with intrinsically mixed states. I aim here to introduce them to a wider audience—and to encourage that audience to cultivate their acquaintance (...) by suggesting that intrinsically mixed states undermine assumptions framing standard discussions of the quantum measurement problem. (shrink)

Constructive and intuitionistic Zermelo-Fraenkel set theories are axiomatic theories of sets in the style of Zermelo-Fraenkel set theory (ZF) which are based on intuitionistic logic. They were introduced in the 1970's and they represent a formal context within which to codify mathematics based on intuitionistic logic. They are formulated on the basis of the standard first order language of Zermelo-Fraenkel set theory and make no direct use of inherently constructive ideas. In working in constructive and intuitionistic ZF we can thus (...) to some extent rely on our familiarity with ZF and its heuristics. -/- Notwithstanding the similarities with classical set theory, the concepts of set defined by constructive and intuitionistic set theories differ considerably from that of the classical tradition; they also differ from each other. The techniques utilised to work within them, as well as to obtain metamathematical results about them, also diverge in some respects from the classical tradition because of their commitment to intuitionistic logic. In fact, as is common in intuitionistic settings, a plethora of semantic and proof-theoretic methods are available for the study of constructive and intuitionistic set theories. -/- The entry introduces the main features of Constructive and Intuitionistic ZF and offers links to the relevant bibliography. (shrink)

Medical advances in transplantation techniques have driven an exponential increase in the demand for transplantable organs. Unfortunately, policy efforts to bolster the organ supply have been less than effective, failing to provide a stopgap for ever-increasing numbers of patients who await organ transplantation. The number of registrations on waiting lists exceeded 65,245 in early 1999, a 325% increase over the 20,000 that existed 11 years earlier in 1988. Regrettably, more than 4,000 patients die each year while awaiting transplantation.

The human brain is in great part what it is because of the functional and structural properties of the 100 billion interconnected neurons that form it. These make it the body’s most complex organ, and the one we most associate with concepts of selfhood and identity. The assumption held by many supporters of human enhancement, transhumanism, and technological posthumanity seems to be that the human brain can be continuously improved, as if it were another one of our machines. In this (...) paper, I focus on some of the ethical issues that we should keep in mind when thinking about memory enhancement interventions. I start with an overview of one of the most precious capacities of the brain, namely memory. Then I analyze the different kinds of memory interventions that exist or are under research. Finally, I point out the issues that we should not forget when we consider enhancing our memories. In this regard, my argument is not against memory enhancement interventions; rather, it concentrates on the need to “keep in mind” what kind of enhancements we want. We should consider whether we want the kind of “enhancements” that will end up making us lose synapse connections, or the kind that promote more use of them. (shrink)

This is the first of a two-part introduction to some interpretive questions that arise in connection with quantum field theories (QFTs). Some of these questions are continuous with those familiar from the discussion of ordinary non-relativistic quantum mechanics (QM). For example, questions about locality can be rigorously posed and fruitfully pursued within the framework of QFT. A stark disanalogy between QFTs and ordinary QM – the former, but not the latter, typically admit infinitely many putatively physically inequivalent realizations – prompts (...) relatively novel questions, questions about how to understand and adjudicate different strategies for equipping quantum theories with content. Part I sketches the fate of locality and related notions in QFT, then documents the non-uniqueness unprecedented in ordinary QM but rampant in QFT. Part II presents foundations issues raised by non-uniqueness. (shrink)

The Dedekind cuts in an ordered set form a set in the sense of constructive Zermelo—Fraenkel set theory. We deduce this statement from the principle of refinement, which we distill before from the axiom of fullness. Together with exponentiation, refinement is equivalent to fullness. None of the defining properties of an ordering is needed, and only refinement for two—element coverings is used. In particular, the Dedekind reals form a set; whence we have also refined an earlier result by Aczel and (...) Rathjen, who invoked the full form of fullness. To further generalise this, we look at Richman's method to complete an arbitrary metric space without sequences, which he designed to avoid countable choice. The completion of a separable metric space turns out to be a set even if the original space is a proper class; in particular, every complete separable metric space automatically is a set. (shrink)