A simple, fact-filled introduction for the smallest citizen on the judicial branch of the government.

"Paleontologists like to say that to a first approximation, all species are extinct (ninety- nine percent is the usual estimate). The organisms we see around us are distant cousins, not great grandparents; they are a few scattered twig-tips of an enormous tree whose branches and trunk are no longer with us." (p. 343-44). The historical life bush consists mainly in dead ends.

There is an urgent need to understand how private and public organisations can play a role in promoting human values such as fairness, dignity, respect and care. Globalisation, technological advance and climate change are changing work, organisations and systems in ways which foster inequality, alienation and collective risk. Against this backdrop, organisations are being urged to make their contribution to the common good, take account of the interests of multiple stakeholders, and respond ethically as well as efficiently to complex challenges (...) which transcend traditional organisational and state boundaries. Ethics, Meaningfulness, and Mutuality poses critical questions related to organisational design by challenging limits to current thinking, such as the neglect by political philosophers of markets, firms and stakeholders, or by organisational theorists of business ethics. In so doing, the book advances our understanding of the theory and practice of ethical organising. Specifically, meaningfulness and mutuality will be used to yield values and principles for a philosophy of ethical organising which includes an account of human values in morally desirable collective action, and examines the relationship of collective action to the contested concept of shared value creation. Within a philosophy of ethical organising, mutuality permits an examination of the unavoidable relational nature of collective action, whereas meaningfulness addresses fundamental human concerns for significance and leading a life we have reason to value. By addressing our status as relational beings with human needs for meaning, a philosophy of ethical organising brings critical thinking to the creation of morally informed organisational practices which are not only instrumentally beneficial for addressing wicked problems, but are normatively desirable for human flourishing. (shrink)

The mythical1 hungry ass, facing two identical bundles of hay equidistant from him, has engendered two related questions. Can he choose one of the bundles, there seemingly being nothing to incline him one way or the other? If he can, the second puzzle — pertaining to rational choice — arises. It seems the ass cannot rationally choose one of the bundles, because there is no sufficient reason for any choice.2In what follows, I will argue that choice is possible even when (...) there is no option which is better than the others (section II), and that it is perfectly reasonable to choose an option even when there is no sufficient reason for it (section III). I will then (section IV) point to another puzzling feature of the .. (shrink)

It is always gratifying when another scholar endorses one's own publicly stated position on a controversial matter. It was therefore with distinct appreciation that I read John Banja's article crit...

RNA localization is a powerful strategy used by cells to localize proteins to subcellular domains and to control protein synthesis regionally. In germ cells, RNA targeting has profound implications for development, setting up polarities in genetic information that drive cell fate during embryogenesis. The frog oocyte offers a useful system for studying the mechanism of RNA localization. Here, we discuss critically the process of RNA localization during frog oogenesis. Three major pathways have been identified that are temporally and spatially separated (...) in oogenesis. Each pathway uses a different mechanism to effect RNA localization. In some cases, localization elements within the 3' untranslated region have been identified and have provided unique insights into the localization process. This important field is still in its infancy, however, and much remains to be learned. BioEssays 21:546–557, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

ExcerptVassilios Paipais, ed. Theology and World Politics: Metaphysics, Genealogies, Political Theologies. Cham: Palgrave Macmillan, 2020. Pp. xiv + 349. Political theology represents one of the most fundamental subfields of contemporary political theory and international political theory. Since the 1920s, when Carl Schmitt introduced the respective terminology in the broader field of social and political sciences, political theology has developed in a dynamic way, composing, one way or another, a broader interdisciplinary field in which philosophy, theology, and politics are fruitfully interconnected.

The Deleuzian model and the masochistic contract -- Masochism, feminine "goodness" and sacrifice -- Self-mutilation and (a)signification -- Transgressive reconfigurations -- Heterocosms, spectres and the world remade -- Postscrip.

Based on A. P. D. Mourelatos's "Events, Processes, and States", an overview of the literature on „verb types‟ is provided in this paper;the basic conceptual, logical and grammatical tests for the identification of different verb types are also briefly reviewed.Such tests, it is argued, reveal variations in a verb’s grammatical and/or lexical aspect; accordingly, verb types should be viewed as regularities governing aspectual variation within and across sentences. Verb types are not associated with particular verbs, predicates or sentences; rather, a (...) verb type is the sum of ways in which a verb‟s aspect may vary. In other words, verb types describe the possibilities for a verb to appear in one or another of a series of interrelated constructions. Verb types are verbal possibilities or, to use B. L. Whorf‟s apt term, fashions of speaking which cut across typical grammatical classifications. It is further argued that verb types, as “mere” fashions of speaking, cannot provide a firm basis for any metaphysics of „situation types‟; i.e., the metaphysics of verb types cannot be founded on their linguistics. (shrink)

Das Werk des erst nach seinem Tod wiederentdeckten galizischen Schriftstellers Soma Morgenstern ist geprägt von der Identitätssuche des jüdischen Intellektuellen im 20. Jahrhundert. Nach der Shoah wendet er sich im amerikanischen Exil vom christlichen Europa ab, dem er die religiöse Schuld an diesem Massenmord zuweist. "Die Blutsäule" schreibt er gleichwohl in einem ganz eigenen Deutsch mit vielen Anklängen an die Sprache der Bibel; insofern diese Sprache zugleich die der 'verhassten' Täter bleibt, entsteht eine komplexe Romankonstruktion, deren religiöser wie zeitgeschichtlicher und (...) literarischer Hintergrund rekonstruiert wird. (shrink)

Activating Transcription Factor-2 is a sequence-specific DNA-binding protein that belongs to the bZIP family of proteins and plays diverse roles in the mammalian cells. In response to stress stimuli, it activates a variety of gene targets including cyclin A, cyclin D and c-jun, which are involved in oncogenesis in various tissue types. ATF-2 expression has been correlated with maintenance of a cancer cell phenotype. However, other studies demonstrate an antiproliferative or apoptotic role for ATF-2. In this review, we summarize the (...) signaling pathways that activate ATF-2, as well as its downstream targets. We examine the role of ATF-2 in carcinogenesis with respect to other bZIP proteins, using data from studies in human cancer cell lines, human tumours and mouse models, and we propose a potential model for its function in carcinogenesis, as well as a theoretical basis for its utility in anticancer drug design. (shrink)

Challenging the posthumanist canon which celebrates the pre-eminence of matter, Ruth Miller, inFlourishingThoughtargues that what nonhuman systems contribute to democracy is thought. Drawing on recent feminist theories of nonhuman life and politics, Miller shows that reproduction and flourishing are not antithetical to contemplation and sensitivity. After demonstrating processes of life and processes of thought are indistinguishable, Miller finds that four menacing accumulations of matter and information--global surveillance, stored embryos, human clones, and reproductive trash--are politically productive rather than threats to (...) democratic politics. As a consequence, she questions the usefulness of individual rights such as privacy and dignity, contests the value of the rational metaphysics underlying human-centered political participation, and re-evaluates the gender relations that derive from this type of participation. Ultimately, in place of these human-centered structures, Miller posits a more meditative mode of democratic engagement. Miller's argument has shattering implications for the debates over the proper use and disposal of embryonic tissue, alarms about data gathering by the state and corporations, and other major ethical, social, and security issues. (shrink)

This article considers two arguments that purport to show that inductive reasoning is unjustified: the argument adduced by Sextus Empiricus and the (better known and more formidable) argument given by Hume in the Treatise. While Sextus’ argument can quite easily be rebutted, a close examination of the premises of Hume’s argument shows that they are seemingly cogent. Because the sceptical claim is very unintuitive, the sceptical argument constitutes a paradox. And since attributions of justification are theoretical, and the claim that (...) they are never (or seldom) true isn’t preposterous, the correct response to the paradox may well be to admit that the sceptic has exposed our error in making them. (shrink)

Die Münchener Texte und Untersuchungen zur deutschen Literatur des Mittelalters (MTU), seit Band 102 beim Max Niemeyer Verlag, machen bisher nicht oder ungenügend erschlossene Texte, Stoffe und Gattungen zugänglich. Neben höfischem und Heldenepos und der Lieddichtung des Hohen und Späten Mittelalters sind vor allem auch Prosaschriften des weltlichen und geistlichen Bereichs, vom theologischen Traktat über die Mystik bis zum Spiel und zur Sachliteratur aus der mittelalterlichen Alltagswelt vertreten. Die Auswahl der publizierten Werke besorgt ein internationales Gremium von Mediävisten verschiedener Disziplinen.

This article focuses on the access of people in developing countries to medications and medical services that are readily available to inhabitants of industrialized countries. There are, of course, other critical dimensions of public health that require action on a global scale. These include relief for large numbers of people who are starving or living at nearly subsistence levels; provision of a supply of clean, potable water for populations deprived of that essential resource; and the consequences for local agricultural production (...) in countries in which globalization has led to deforestation of vast portions of the land. The focus here on access to health services and needed medications is not intended to minimize the importance of these other areas of global health. (shrink)

In this article I consider the normative and axiological dimension of Simmel’s thought. Building on previous interpretations, I argue that although Simmel cannot be interpreted as a systematic normative theorist, the issue of values and the normative standpoint can nevertheless be traced in various aspects of his multifarious work. This interpretive turn attempts to link Simmel’s obscure theory of value with his epistemological relationism. Relationism may offer a counterweight to Simmel’s value-pluralism, since it points to normative elements (e.g. internal teleology, (...) justice) that can contribute to the reconciliation between incommensurablity of forms and totality. Axiological and normative concerns (of a Hegelian source) survive also in his metaphysics of life, pointing beyond a merely Bergsonian and conservative Lebensphilosophie. I conclude with some thoughts on how this normative rethinking of Simmel’s thought can contribute towards more adequate appreciations of Simmel’s overall theory. (shrink)

Addison and Steele’s legacy on polite manners has been widely acknowledged as a hallmark of the Scottish Enlightenment’s tradition. On the other hand the place of courtly, ‘French’ politeness within the Scottish Enlightenment is much less debated. Conceiving the European Enlightenment as a status quo built on ‘French manners and English liberty’, as Pocock perfectly synthesizes1, points out to the restrictions imposed on religious fanaticism and warfare by the ‘jus gentium’ and European civility. In my paper I aim to shift (...) the attention to the seemingly obvious fact that manners, the backbone of European civility, originate in court, and Versailles was the court par excellence. In this context I explore Adam Smith’s struggle to strip politeness and civility of its aristocratic components. In the heart of the matter lies the strange idea of courtoisie without a court, of propriety that should overcome formal politeness i.e. imitation of aristocratic manners. (shrink)

Nel 1589 Hercole Filogenio scrisse un discorso che intitolò _Dell’eccellenza della donna_, con l’intento di allinearsi “all’opinione di coloro che si sforzano scoprire l’errore di molti, quali tanto si affannano in avilire il feminil sesso” e dedicò il suo scritto a Flavia Peretti Orsina, donna distinta e dallo spirito inquieto, che con i suoi interessi contribuì allo sviluppo della società dell’epoca. Nel suo tentativo di preservare le donne dal biasimo manifestato dal maschilismo egemone e, allo stesso tempo, elogiare le loro (...) virtù, Filogenio propone due conclusioni, l’analisi e l’approfondimento delle quali, per mezzo di un’argomentazione valida, costituiscono il nucleo testuale della sua opera. L’articolo presenta e analizza i ragionamenti che Filogenio sviluppa nella seconda parte del suo discorso sui quali intende imperniare la dimostrazione della seconda conclusione: che la Donna non è superiore né inferiore all’Uomo, ma simile e uguale per nobiltà, eccellenza e perfezione. (shrink)

Congo Style presents a postcolonial approach to discussing the visual culture of two now-notorious regimes: King Leopold II's Congo Colony and the state sites of Mobutu Sese Seko's totalitarian Zaïre. Readers are brought into the living remains of sites once made up of ambitious modernist architecture and art in Kinshasa, Democratic Republic of the Congo. From the total artworks of Art Nouveau to the aggrandizing sites of post-independence Kinshasa, Congo Style investigates the experiential qualities of man-made environments intended to entertain, (...) delight, seduce and impress. In her study of visual culture, Ruth Sacks sets out to reinstate the compelling wonder of nationalist architecture from Kinshasa's post-independence era, such as the Tower of the Exchange (1974), Gécamines Tower (1977), and the artworks and exhibitions that accompanied them. While exploring post-independence nation-building, this book examines how the underlying ideology of Belgian Art Nouveau, a celebrated movement in Belgium, led to the dominating early colonial settler buildings of the ABC Hotels (circa 1908-13). Congo Style combines Sacks's practice as a visual artist and her academic scholarship to provide an original study of early colonial and independence-era modernist sites in their African context. (shrink)

In liberal political theory, meaningful work is conceptualised as a preference in the market. Although this strategy avoids transgressing liberal neutrality, the subsequent constraint upon state intervention aimed at promoting the social and economic conditions for widespread meaningful work is normatively unsatisfactory. Instead, meaningful work can be understood to be a fundamental human need, which all persons require in order to satisfy their inescapable interests in freedom, autonomy, and dignity. To overcome the inadequate treatment of meaningful work by liberal political (...) theory, I situate the good of meaningful work within a liberal perfectionist framework, from which standpoint I develop a normative justification for making meaningful work the object of political action. To understand the content of meaningful work, I make use of Susan Wolf’s distinct value of meaningfulness, in which she brings together the dimensions of objectivity and subjectivity into the ‘bipartite value’ of meaningfulness (BVM) (Wolf, Meaning in life and why it matters, 2010). However, in order to be able to incorporate the BVM into our lives, we must become valuers, that is, co-creators of values and meanings. This demands that we acquire the relevant capabilities and status as co-authorities in the realm of value. I conclude that meaningful work is of first importance because it is a fundamental human need, and that society ought to be arranged to allow as many people as possible to experience their work as meaningful through the development of the relevant capabilities. (shrink)

Sophie de Grouchy, marquise de Condorcet, réinterprète la doctrine de la sympathie propre à la tradition moraliste écossaise dans le sens d’une réévaluation de ses origines physiologiques, ce qui affecte profondément ses dimensions morales et sociales. Dans le cadre d’un rousseauisme compassionnel, elle transforme Adam Smith en un républicain sentimentaliste modéré, précurseur des Idéologues. Elle s’emploie pour cela à montrer que la déférence envers le pouvoir établi, surtout la royauté, érigée par Adam Smith en servilité quasi fétichiste envers les puissants (...) et les rois, doit être réexaminée dans le cadre d’une économie affective post-révolutionnaire. Malgré le risque d’un mimétisme affectif enflammé par une rhétorique démagogique, Sophie de Grouchy mise sur la moralisation de l’identification avec la souffrance humaine, et sur sa régulation par des lois et institutions réformées pour tenir compte d’une nature humaine profondément sympathique. L’institutionnalisation de la sympathie morale est censée porter remède aux tragédies dues à la ségrégation sociale. En revanche, Adam Smith souligne à la fois la corruption morale due à l’adulation des puissants, et l’illusion socialement utile d’un imaginaire collectif cultivé par la tragédie classique et peuplé d’idéalisations du statut social. Adam Smith explore en outre d’une façon originale une dimension quasi psychanalytique de l’idéal social du moi qui anticipe la problématisation du culte du chef, là où la marquise se contente de critiquer le meneur de foule. (shrink)

Adam Smith not only champions commerce, he also criticizes it. In this criticism Smith draws critically upon a long-standing concern in enlightenment’s culture about the proper basis of political and moral life. For the purposes of this chapter, we can identify two interrelated dimensions in Smith’s analysis of the relation between corruption and commerce. He focuses on atavistic remainders of pre-modern, feudal, or aristocratic aspects of behaviour within the heart of commercial society and considers obsequiousness as emblematic of dependent socio-economic (...) relationships while, simultaneously, he raises the issue of distinct socio-economic, moral and political forms of commercial corruption, endemic to the core of commercial polity. (shrink)

In his famous Der Nomos der Erde, while discussing the foundational role of Francisco de Vitoria’s work for the emergence of international law, especially with regard to the legal and political justifications of the territorial conquest of a new world, Carl Schmitt—quite well-known as an enemy of modern and contemporary humanism—offers the following reflection.

This book presents the necessary methods and resources for managers and directors to be successful in leading their corporations in a responsible and morally conscious manner and examining the dangers of unethical behavior.

Derived from Ruth Williams' more than 40-year immersion in spiritual practice, as well as her clinical experience as a Jungian analyst, this thought-provoking volume explores the nature of spiritual paths and trajectories in practical ways, incorporating personal anecdote and ground-breaking academic research and providing a window into how Jungian practitioners work with soul and spirit. Williams explores the nature of being a human using the Yiddish idea of a person being a 'mensch,' which means being a decent human being, (...) having humanity and living ethically with integrity. The idea of 'grace' is the thread that runs through the book-the mystery that binds things together and makes life meaningful, purposeful, potentially joyful and spiritually fulfilling. Williams sees 'grace' as being that which underpins and lies behind synchronicity and divinatory practices and as a force by which we can learn to be guided. Rooted in clinical work, Exploring Spirituality from a Post-Jungian Perspective is fascinating reading for Jungian analysts, therapists and academics, as well as for general readers interested in a spiritual journey, both personally and for clinical purposes. (shrink)