Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The theme of the third annual Spring workshop of the HUPO-PSI was proteomics and beyond and its underlying goal was to reach beyond the boundaries of the proteomics community to interact with groups working on the similar issues of developing interchange standards and minimal reporting requirements. Significant developments in many of the HUPO-PSI XML interchange formats, minimal reporting requirements and accompanying controlled vocabularies were reported, with many of these now feeding into the broader efforts of the Functional Genomics Experiment data (...) model and Functional Genomics Ontology ontologies. (shrink)

Philosophy is shaped by life and life is shaped by philosophy. This is reflected in The Philosophical I, a collection of 16 autobiographical essays by prominent philosophers.

Best known for reviving the tradition of classical liberalism, F. A. Hayek was also a prominent scholar of the philosopher John Stuart Mill. One of his greatest undertakings was a collection of Mill’s extensive correspondence with his longstanding friend and later companion and wife, Harriet Taylor-Mill. Hayek first published the Mill-Taylor correspondence in 1951, and his edition soon became required reading for any study of the nineteenth-century foundations of liberalism. This latest addition to the University of Chicago Press’s (...) Collected Works of F. A. Hayek series showcases the fascinating intersections between two of the most prominent thinkers from two successive centuries. Hayek situates Mill within the complex social and intellectual milieu of nineteenth-century Europe—as well as within twentieth-century debates on socialism and planning—and uncovers the influence of Taylor-Mill on Mill’s political economy. The volume features the Mill-Taylor correspondence and brings together for the first time Hayek’s related writings, which were widely credited with beginning a new era of Mill scholarship. (shrink)

Charles Taylor has been one of the most original and influential figures in contemporary philosophy: his 'philosophical anthropology' spans an unusually wide range of theoretical interests and draws creatively on both Anglo-American and Continental traditions in philosophy. A selection of his published papers is presented here in two volumes, structured to indicate the direction and essential unity of the work. He starts from a polemical concern with behaviourism and other reductionist theories (particularly in psychology and the philosophy of language) (...) which aim to model the study of man on the natural sciences. This leads to a general critique of naturalism, its historical development and its importance for modern culture and consciousness; and that in turn points, forward to a positive account of human agency and the self, the constitutive role of language and value, and the scope of practical reason. The volumes jointly present some two decades of work on these fundamental themes, and convey strongly the tenacity, verve and versatility of the author in grappling with them. They will interest a very wide range of philosophers and students of the human sciences. (shrink)

The place of religion in society has changed profoundly in the last few centuries, particularly in the West. In what will be a defining book for our time, Taylor takes up the question of what these changes mean, and what, precisely, happens when a society becomes one in which faith is only one human possibility among others.

The reason of faith -- Thought and language -- Truth -- The Monologion arguments for the existence of God -- The Proslogion argument for the existence of God -- The divine attributes -- Thinking and speaking about God -- Creation and the word -- The Trinity -- Modality -- Freedom -- Morality -- Incarnation and atonement -- Original sin, grace, and salvation.

This classic, provocative introduction to classical metaphysical questions focuses on appreciating the problems, rather than attempting to proffer answers.

Ludwig Wittgenstein hat in seinem späten Werk »Philosophische Untersuchungen« die grammatische Beschreibung unserer lebensweltlichen Handlungen ins Zentrum seiner Überlegungen gestellt. Diese Abkehr von essentialistisch-aristotelischen Wesensdefinitionen in der Philosophie hat bis heute nichts von ihrer Sprengkraft verloren. Mit Habermas sind die »weltkonstituierenden Leistungen« im 20. Jahrhundert auf »grammatische Strukturen« übergegangen. Die Rede des Subjekts von sich selbst erscheint dann in einem neuen Licht: Es ist in einer grammatischen Weise verfasst, im Wissen um die ständige Veränderbarkeit jener Regelsysteme, die durch die Orientierung (...) an grammatischen Standards in die Praxis überführt und dort temporär stabilisiert werden. Erstmals beschreibt der Band die Kategorie der Grammatischen Subjektivität als Erweiterung des Referenzrahmens, innerhalb dessen Menschen von sich sprechen: im Blick auf Themen wie Wissen, Ethik, Politik, die Umstände der Moderne oder den Begriff des Cogito. (shrink)

A beautifully written, deeply provocative inquiry into the intersection between animal and disability liberation--the debut of an important new social critic How much of what we understand of ourselves as "human" depends on our physical and mental abilities--how we move (or cannot move) in and interact with the world? And how much does our definition of "human" depend on its difference from "animal"? Drawing on her own experiences as a disabled person, a disability activist, and an animal advocate, author Sunaura (...) Taylor persuades us to think deeply, and sometimes uncomfortably, about what divides the human from the animal, the disabled from the nondisabled--and what it might mean to break down those divisions, to claim the animal and the vulnerable in ourselves, in a process she calls "cripping animal ethics." Beasts of Burden suggests that issues of disability and animal justice--which have heretofore primarily been presented in opposition--are in fact deeply entangled. Fusing philosophy, memoir, and science--including factory farming, disability oppression, or our assumptions of human superiority over animals--Taylor draws attention to new worlds of experience and empathy that will open up important avenues of solidarity across species and ability. Beasts of Burden is a wonderfully engaging and elegantly written work, both philosophical and personal, by a brilliant debut author. (shrink)

This authored book provides an innovative and systematic account of key debates within the social psychology of knowledge, using the theory of social representations as a guide. This account is then elaborated and integrated into a conceptually coherent theoretical framework to further the social psychological dimensions of the relationship between representations, knowledge and context. Jovchelovitch highlights the social psychological components of the process of knowledge formation and their impact in the constitution of communities, culture and public spheres. Whilst this exploration (...) contributes to an understanding of the genesis, logic and function of knowledge in social life, it also shows that context is essential to understanding the dynamics of representation and emphasises the fundamental unity between the two. This book offers a significant and stimulating contribution to the field of social representations and will make essential reading for those wanting to follow this debate at thecutting edge of social, cultural and developmental psychology as well as sociology, anthropology and cultural studies. (shrink)

Bioethics at the Movies explores the ways in which popular films engage basic bioethical concepts and concerns. Twenty philosophically grounded essays use cinematic tools such as character and plot development, scene-setting, and narrative-framing to demonstrate a range of principles and topics in contemporary medical ethics. The first section plumbs popular and bioethical thought on birth, abortion, genetic selection, and personhood through several films, including The Cider House Rules, Citizen Ruth, Gattaca, and I, Robot. In the second section, the contributors examine (...) medical practice and troubling questions about the quality and commodification of life by way of Dirty Pretty Things, Eternal Sunshine of the Spotless Mind, and other movies. The third section's essays use Million Dollar Baby, Critical Care, Big Fish, and Soylent Green to show how the medical profession and society at large view issues related to aging, death, and dying. A final section makes use of Extreme Measures and select Spanish and Japanese films to discuss two foundational matters in bioethics: the role of theories and principles in medicine and the importance of cultural context in devising care. Structured to mirror bioethics and cinema classes, this innovative work includes end-of-chapter questions for further consideration and contributions from scholars from the United States, Canada, the United Kingdom, Israel, Spain, and Australia. Contributors: Robert Arp, Ph.D., Michael C. Brannigan, Ph.D., Matthew Burstein, Ph.D., Antonio Casado da Rocha, Ph.D., Stephen Coleman, Ph.D., Jason T. Eberl, Ph.D., Paul J. Ford, Ph.D., Helen Frowe, M.A., Colin Gavaghan, Ph.D., Richard Hanley, Ph.D., Nancy Hansen, Ph.D., Al-Yasha Ilhaam, Ph.D., Troy Jollimore, Ph.D., Amy Kind, Ph.D., Zana Marie Lutfiyya, Ph.D., Terrance McConnell, Ph.D., Andy Miah, Ph.D., Nathan Norbis, Ph.D., Kenneth Richman, Ph.D., Karen D. Schwartz, LL.B., M.A., Sandra Shapshay, Ph.D., Daniel Sperling, LL.M., S.J.D., Becky Cox White, R.N., Ph.D., Clark Wolf, Ph.D. (shrink)

Gary Kemp: Quine's Relationship with Analytic Philosophy: I try to explain why Quine, for all his fame amongst analytic philosophers, has so few explicit followers within analytic philosophy of the past fifty years – despite the fact that naturalism, at least as broadly conceived, is so popular. Partly it's because Quine's particular version of naturalism is so demanding, partly it's because the nature and seriousness of his commitment to extensionalism are not well recognized, and partly because his views were formulated (...) from an extremely general and abstract point of view in the philosophy of science. I focus on the second and especially on the third. Quine is more radical and more alien than is customarily appreciated. (shrink)

Burnout is a phenomenon characterized by fatigue and frustration, usually related to work stress and dedication to a cause, a way of life that does not match the person’s expectations. Although it seems to be associated with risk factors stemming from a professional environment, this problem may affect any person. Palliative care is provided in a challenging environment, where professionals often have to make demanding ethical decisions and deal with death and dying. This article reports on the findings of a (...) systematic review aimed at identifying described burnout levels in palliative care nurses and physicians, and the related risks and protective factors. The main findings indicate that burnout levels in palliative care, or in health care settings related to this field, do not seem to be higher than in other contexts. (shrink)

Philosophe française contemporaine, Sandra Laugier a ouvert de nouveaux champs intellectuels au cours des trente dernières années en se faisant la passeuse et la penseuse de la vie ordinaire. Passeuse, avec ses traductions de Stanley Cavell (1926-2018) dans la suite du grand philosophe américain Ralph Waldo Emerson (1803-1882). Penseuse par l'édification de son domaine de réflexion propre. Elle a aussi bien exploré la philosophie analytique que la philosophie morale, les potentialités de la désobéissance civile comme celles de l'éthique féministe (...) du care, ou la radicalité aux États-Unis sur les questions de genre et de race. Son analyse de la culture populaire, à travers l'étude qu'elle a faite des séries télévisées, est elle aussi significative.00Aujourd'hui, la philosophe dresse un premier bilan raisonné de sa trajectoire. Pour ce faire, elle a choisi la forme du dialogue qui sied à sa démarche. Cette conversation menée par le journaliste Philippe Petit nous aide à mieux la connaître.00Une biographie existentielle et intellectuelle. (shrink)

Introduction to Hegel's thought for the student and general reader, emphasizing in particular his social and political thought and his continuing relevance to contemporary problems.

Longstanding philosophical debate over the semantics of proper names has yet to examine the distinctive behavior of deadnames, names that have been rejected by their former bearers. The use of these names to deadname individuals is derogatory, but deadnaming derogates differently than other kinds of derogatory speech. This paper examines different accounts of this behavior, illustrates what going views of names will have to say to account for it, and articulates a novel version of predicativism that can give a semantic (...) explanation for this derogation. (shrink)

Loris Malaguzzi (1920 - 1994) was the pioneer of the Reggio Emilia approach to teaching young children. An ever-increasing number of teachers and educationalists from all over the world now come to study the Reggio pre-school's unique methods, and this is largely due to Malaguzzi's devotion, work and commitment over 45 years, and the small group of teachers and educators he trained and with whom he developed his methods. The principles that underpin the Reggio Emilia approach are fundamental to the (...) way in which Early Childhood Education is being shaped around the world today. The work of Loris Malaguzzi was rooted in a strong sociocultural framework, meaning it was a considered response to what was needed for particular communities and their needs. Sandra Smidt here considers the life of this remarkable man, and through a pedagogical perspective explores his approach on topics including: - Relationships; - Observation; - Creativity; - Questioning; - Justice; - Equality; - Politics. Accessible and informative, this introductory yet in-depth look at Malaguzzi's life and work will be of huge benefit to anyone working with young children in an educational capacity, including parents, and will be essential reading for students on early childhood education courses. (shrink)

In this essay, I revisit and extend my arguments for a view of science that is pluralistic, perspectival and pragmatist. I attempt to resolve mismatches between metaphysical assumptions, epistemological desiderata, and scientific practice. I consider long-held views about unity of science and reductionism, emergent properties and physicalism, exceptionless necessity in explanatory laws, and in the justification for realism. My solutions appeal to the partiality of representation, the perspectivism of theories and data, and the interactive co-construction of warranted claims for realism.

This book focuses on binomials (word pairs such as heart and soul, rich and poor, or if and when), and in particular on the degree of reversibility that English binomials demonstrate. Detailed and innovative corpus linguistic analyses investigate the correlates of the degree of reversibility, linguistic constraints that influence the ordering and reversibility of binomials and the diachronic development of reversibility. In addition, judgment data are analyzed for their convergence and divergence with corpus data regarding degrees of reversibility. The book (...) thus establishes reversibility as a complex characteristic of the binomial construction, at the same time throwing light on general questions in phraseology, lexicalization, language structure and language processing. (shrink)

La Jaiminiyasamhita, en partie inédite, est une œuvre puranique de nature "encyclopédique". Dans une section de six chapitres intitulée "La question de Janaka" ('Janakaprasna'), le roi Kartaviryarjuna rend visite à Dattatreya, afin de recevoir un enseignement sur l''advaita', la "non-dualité". Ce dernier lui rapporte l'enseignement que le sage Asita transmit autrefois au roi mythique Janaka. Cette "question de Janaka", à l'instar des Upanisad, se présente sous la forme d'un dialogue entre un maître et un disciple. La thématique au cœur de (...) ce dialogue concerne la nature du 'brahman' et son rapport au corps. Elle permet à l'auteur de faire montre de l'étendue de son savoir dans des domaines aussi riches que variés: le développement embryonnaire et les théories physiologiques, les conceptions cosmogoniques, les paradoxes de la non-dualité et les disciplines de salut, en particulier le yoga, influencé par des conceptions tantriques. (shrink)

The famous Brazilian educator Paulo Freire has influenced educators, teachers and students in a broad tapestry of contexts and countries, as he challenged conventional thinking on how teachers ought to teach and learners ought to learn. By making his ideas accessible and relevant, this insightful and thought-provoking text draws out the relevance and topicality of Freire's work and applies this to a wide range of educational settings, from adult education, through schools, to early years settings. Themes covered include: the lasting (...) impact of illiteracy; the benefits and potential in becoming literate; literacy, language and power; the differences between banking and dialogic education; the social and political nature of learning. what kind of teaching and learning do we want? Using a variety of practical examples and case studies, Introducing Freire is an essential guide to the work of one of the most significant figures in education in the last century. Fascinating and accessible, this book is for anyone interested in teaching and learning, poverty and affluence, power and powerlessness, and society and change. (shrink)

This chapter contains sections titled: The Kantian Symbol The Schopenhauerian Metaphor? The Schopenhauerian Metonymy Gracián's Poetics and Schopenhauer as Poetic Metaphysician Conclusion References.