Proposals to compensate families for transplantable organs are gathering momentum. These proposals assume that the body is not integral to the self—that it can be treated like property. Most people believe otherwise.

Recent work on the evolution of utility has brought the blunt instrument of kin selection closer to the cluttered scalpel kit of social science. The concept of diminishing marginal utility can help streamline the latter. Reconciling ultimate causes with proximate inclinations, however, will be easier for the case of assistance from grandparents than assistance to them.

Abstract This paper defends an argument from interpretation against the possibility of massive error. The argument shares many important features with Donald Davidson's famous argument, but also key differences. I defend the argument against claims that it begs the question against scepticism and that it leaves the sceptic with an obvious means of escape.

Recent reports of CRISPR/Cas9 genome editing in parasitic helminths open up new avenues for research on these dangerous pathogens. However, the complex morphology and life cycles inherent to these parasites present obstacles for the efficient application of CRISPR/Cas9‐targeted mutagenesis. This is especially true with the trematode flukes where only modest levels of gene mutation efficiency have been achieved. Current major challenges in the application of CRISPR/Cas9 for study of parasitic worms thus lie in enhancing gene mutation efficiency and overcoming issues (...) involved in host passage so that mutated parasites survive. Strategies developed for CRISPR/Cas9 studies on Caenorhabditis elegans, protozoa and mammalian cells, including novel delivery methods, the choice of selectable markers, and refining mutation precision represent novel tactics whereby these impediments can be overcome. Furthermore, employing CRISPR/Cas9‐mediated gene drive to interfere with vector transmission represents a novel approach for the control of parasitic worms that is worthy of further exploration. (shrink)

The most popular and convincing arguments for the claim that vegetarianism is morally obligatory focus on the extensive, unnecessary harm done to animals and to the environment by raising animals industrially in confinement conditions (factory farming). I outline the strongest versions of these arguments. I grant that it follows from their central premises that purchasing and consuming factoryfarmed meat is immoral. The arguments fail, however, to establish that strict vegetarianism is obligatory because they falsely assume that eating vegetables is the (...) only alternative to eating factory-farmed meat that avoids the harms of factory farming. I show that these arguments not only fail to establish that strict vegetarianism is morally obligatory, but that the very premises of the arguments imply that eating some (non-factory-farmed) meat rather than only vegetables is morally obligatory. Therefore, if the central premises of these usual arguments are true, then strict vegetarianism is immoral. (shrink)

An adaptive preference is a preference that is regimented in response to an agent’s set of feasible options. The fabled fox in the sour grapes story undergoes an adaptive preference change. I consider adaptive preferences more broadly, to include adaptive preference formation as well. I argue that many adaptive preferences that other philosophers have cast out as irrational sour-grapes-like preferences are actually fully rational preferences worthy of pursuit. I offer a means of distinguishing rational and worthy adaptive preferences from irrational (...) and unworthy ones. The distinction is based on the agent’s own appraisal of the adaptive preference. (shrink)

This paper puts forward a general framework for thought about human information processing. It is intended to avoid some of the problems of pipeline or stage models of function. At the same time it avoids the snare of supposing a welter of indefinitely many separate processes. The approach is not particularly original, but rather represents the common elements or presuppositions in a number of modern theories. These presuppositions are not usually explicit, however, and making them so reduces the danger of (...) slipping back into earlier modes of thought.The key point is to distinguish between persisting representations and the processes that translate one representation into another. Various classes or groups of persisting representations can be distinguished by the experimental treatments that interfere with them. In particular, there now seem to be several kinds of short-term or temporary storage, different from each other as well as from longterm memory; the translating processes also have several different modes or kinds. A particularly important aspect of the current position is that a model of this general type no longer requires some external agent to direct and control long sequences of behaviour. (shrink)

There is almost no theoretical discussion of non‐human animal well‐being in the philosophical literature on well‐being. To begin to rectify this, I develop a desire satisfaction theory of well‐being for animals. I contrast this theory with my desire theory of well‐being for humans, according to which a human benefits from satisfying desires for which she can offer reasons. I consider objections. The most important are (1) Eden Lin's claim that the correct theory of well‐being cannot vary across different welfare subjects (...) and (2) his objection against theories of human well‐being that require exercising a sophisticated capacity such as reason giving. (shrink)

One version of the desire satisfaction theory of well-being (i.e., welfare, or what is good for one) holds that only the satisfaction of one's present desires for present states of affairs can affect one's well-being. So if I desire fame today and become famous tomorrow, my well-being is positively affected onlyif tomorrow, when I am famous, I still desire to be famous. Call this the present desire satisfaction theory of well-being. I argue, contrary to this theory, that the satisfaction of (...) past desires that are no longer held does indeed affect one's well-being. The satisfaction of past desires is good for one in that the present satisfaction of past desires positively affects one's past well-being. I argue for this view in stages, starting with the recognition that many of our desires are satisfied not at an instant but over an interval of time, and that it is during this interval of time that our well-being is positively affected. Once we get our foot in the door with some temporal thickness to desire satisfaction and the associated well-being, I argue, the door must open more widely to allow for greater temporal distance between present desire satisfaction and past well-being. I defend my thesis that present satisfaction of past desires increases one's past welfare against objections, including the claim that it involves backward causation and Velleman's claim that the view is highly counterintuitive whether or not it involves backward causation. I argue that some of the objections rely on hedonistic intuitions, intuitions that most desire satisfaction theories of welfare aim to correct. Once properly understood and applied, my counterintuitive and controversial thesis is really quite innocuous. (shrink)

“Moral hazard” is a term familiar in economics and business ethics that illuminates why rational parties sometimes choose decisions with bad moral outcomes without necessarily intending to behave selfishly or immorally. The term is not generally used in medical ethics. Decision makers such as parents and physicians generally do not use the concept or the word in evaluating ethical dilemmas. They may not even be aware of the precise nature of the moral hazard problem they are experiencing, beyond a general (...) concern for the patient's seemingly excessive burden. This article brings the language and logic of moral hazard to pediatrics. The concept reminds us that decision makers in this context are often not the primary party affected by their decisions. It appraises the full scope of risk at issue when decision makers decide on behalf of others and leads us to separate, respect, and prioritize the interests of affected parties. (shrink)

Human attitudes to animals have changed as non-humans have become more widely incorporated in the category of moral agents who deserve some respect. Parallels between the functioning of humans and non-humans have been made for thousands of years but the idea that the animals that we keep can suffer has spread recently. An improved understanding of motivation, cognition and the complexity of social behaviour in animals has led in the last 30 years to the rapid development of animal welfare science. (...) Early attempts to define welfare referred to individuals being in harmony with nature but the first usable definition incorporated feelings and health as part of attempts to cope with the environment. Others considered that welfare is only about feelings but it is argued that as feelings are mechanisms that have evolved they are a part of welfare rather than all of it. Most reviews of welfare now start with listing the needs of the animal, including needs to show certain behaviours. This approach has used sophisticated studies of what is important to animals and has replaced the earlier general guidelines described as freedoms. Many measures of welfare are now used and indicate how good or how poor the welfare is. Naturalness is not a part of the definition of welfare but explains why some needs exist. In recent years, welfare has become established as one of various criteria used to decide on whether a system is sustainable because members of the public will not accept systems that cause poor welfare. The study of welfare has become part of the scientific basis upon which important political decisions are made. (shrink)

This paper provides a method for characterizing space events using the framework of conceptual spaces. We focus specifically on estimating and ranking the likelihood of collisions between space objects. The objective is to design an approach for anticipatory decision support for space operators who can take preventive actions on the basis of assessments of relative risk. To make this possible our approach draws on the fusion of both hard and soft data within a single decision support framework. Contextual data is (...) also taken into account, for example data about space weather effects, by drawing on the Space Domain Ontologies, a large system of ontologies designed to support all aspects of space situational awareness. The framework is coupled with a mathematical programming scheme that frames a mathematically optimal approach for decision support, providing a quantitative basis for ranking potential for collision across multiple satellite pairs. The goal is to provide the broadest possible information foundation for critical assessments of collision likelihood. (shrink)

In a well-known paper, Bernard Williams argues that an immortal life would not be worth living, for it would necessarily become boring. I examine the implications for the boredom thesis of three human traits that have received insufficient attention in the literature on Williams’ paper. First, human memory decays, so humans would be entertained and driven by things that they experienced long before but had forgotten. Second, even if memory does not decay to the extent necessary to ward off boredom, (...) once-satisfied desires often return after a sufficient period of time. Eternity would always contain sufficient time for our desires to rejuvenate. Third, even if too many of our desires were satisfied but not yet rejuvenated, we can expect that human ingenuity would continue to invent new pursuits, pastimes, careers, and ways of life that would prevent us from becoming bored as we moved from one to another. Finally, I consider and respond to several objections, including the claims that as much variety as I propose to be put into an eternal life is inconsistent with having one character throughout one’s life and that the sort of character change and memory decay I postulate is inconsistent with personal identity. (shrink)

Manuel DeLanda discusses his neo-materialist philosophy with Christoph Cox.

This paper is about two seemingly inconsistent theories of well-being and how to reconcile them. The first theory is perfectionism, the view that the good of a human is determined by human nature. The second theory is preferentism, the view that the good of a human lies in the satisfaction of her preferences. I begin by sketching the theories and then developing an objection against each from the standpoint of the other. I then develop a version of each theory that (...) is meant to address the objection from the other theory. It turns out that these modified perfectionist and preferentist theories are mutually supporting and co-extensive. They can be combined into a new theory, perfectionist preferentism, which is an independently plausible theory of well-being. (shrink)

Stakeholder consultation is part of the democratic process, embraces respect for persons, and is necessary for upholding the principle of justice. People are more likely to uphold standards they have participated in setting, so stakeholder consultation encourages adherence to societal and institutional standards as these evolve. Stakeholder consultation is also responsive to the call to “resocialize” ethics by contextualizing dilemmas and involving the destitute in choices about their healthcare. In resource-poor settings, such consultation promotes local “ownership” of, and leadership within, (...) development programs, which enhances effectiveness and sustainability. Stakeholder consultation is, therefore, a form of capacity building. To succeed, it must be responsive to regional, national, and individual constraints, including socioeconomic, cultural, and political ones. Several such constraints impact on the demand for, and availability of, palliative healthcare in the Caribbean. (shrink)

Digital piracy is costly to creative economies across the world. Studies indicate that anti-piracy messages can cause people to pirate more rather than less, suggesting the presence of psychological reactance. A gender gap in piracy behavior and attitudes towards piracy has been reported in the literature. By contrast, gender differences in message reactance and the moderating impact of attitudes have not been explored. This paper uses evolutionary psychology as a theoretical framework to examine whether messages based on real-world anti-piracy campaigns (...) cause reactance and whether this effect is explained by gender and pre-existing attitudes. An experiment compares one prosocial and two threatening messages against a control group to analyze changes in piracy intention from past behavior for digital TV/film. Results indicate that the prosocial message has no significant effect, whereas the threatening messages have significantly opposing effects on men and women. One threatening message influences women to reduce their piracy intentions by over 50% and men to increase it by 18%. We find that gender effects are moderated by pre-existing attitudes, as men and women who report the most favorable attitudes towards piracy tend to demonstrate the most polarized changes in piracy intentions. The practical implications of the results are that men and women process threatening messages differently, therefore behavioral change messages should be carefully targeted to each gender. Explicitly, threatening messages may be effective on women, but may have the reverse effect on men with strong favorable attitudes towards the target behavior. (shrink)

Concept definitions applicable to human and non-human animals should be usable for both. Awareness is a state during which concepts of environment, self, and self in relation to environment result from complex brain analysis of sensory stimuli or constructs based on memory. There are several proposed categories of awareness. The widespread usage of the term conscious is 'not unconscious' so a conscious individual is an individual that has the capability to perceive and respond to sensory stimuli. It is confusing and (...) scientifically undesirable if conscious is also used to mean aware. Hence it is proposed that conscious should be used only as above. Fully functioning and adequately developed humans and members of many other animal species are sentient. Sentience means having the capacity, the level of awareness and cognitive ability, necessary to have feelings. The welfare of an individual is its state as regards its attempts to cope with its environment. This includes feelings, which are important coping mechanisms, and health. Since feelings involve awareness, there is overlap between welfare assessment and awareness assessment. Methods for assessing awareness, consciousness, sentience, and welfare and links to morality are briefly discussed. (shrink)

We prove covering theorems for K, where K is the core model below the sharp for a strong cardinal, and give an application to stationary set reflection.

There is international recognition of the need for sustainable research ethics committees to provide ethical review of human subjects research in developing countries, but many developing countries do not have such committees . Theoretical and practical uncertainties encountered by an IRB on the Caribbean island of Grenada offer insight into ethical review of research in developing countries. Theoretical uncertainties include questions about whether means of ensuring confidentiality and obtaining informed consent will be effective in local settings, and whether deviations from (...) Western norms are justifiable. International guidelines are helpful in addressing these concerns, but are subject to interpretation. Guidelines are less helpful in practical areas like selecting members or chairs. They do not address what sort of procedures and paperwork will work in a developing country, or IRBs’ relationships to governments that have no mandate for them. Experiences presented here show that IRBs in developing countries can sustainably adhere to international standards. Sustainability requires knowledge, personal commitment, and an official mandate to uphold international standards. Capacity building must therefore focus on educational programs to make developing country leaders knowledgeable about the value of international guidelines to their nations. Such knowledge is needed before people will become motivated to promote, implement, and uphold the guidelines. People in developing countries must help design bridges to help their nations put international standards into practice. The structure of such bridges may, of necessity, vary in different settings. (shrink)

Consciousness -- Freedom -- Bad faith -- Authenticity.

A common and convincing argument for the moral requirement of veganism is based on the widespread, severe, and unnecessary harm done to animals, the environment, and humans by the practices of animal agriculture. If this harm footprint argument succeeds in showing that producing and consuming animal products is morally impermissible, then parallel harm footprint arguments show that a vast array of modern practices are impermissible. On this first horn of the dilemma, by engaging in these practices, vegans are living immorally (...) by their own lights. This first horn can be avoided by assuming that morality requires not minimizing harm, but only keeping the harm of our actions within some budget. On the second horn, however, we recognize that there are many ways of keeping our harm footprints within budget other than through our dietary choices. On the second horn of the vegan's dilemma, therefore, veganism is not a moral requirement. (shrink)

We adjudicate a recent dispute concerning the desire theory of well-being. Stock counterexamples to the desire theory include “quirky” desires that seem irrelevant to well-being, such as the desire to count blades of grass. Bruckner claims that such desires are relevant to well-being, provided that the desirer can characterize the object in such a way that makes it clear to others what attracts the desirer to it. Lin claims that merely being attracted to the object of one’s desire should be (...) sufficient for it to be relevant to one’s well-being. The capacity to characterize the desire as Bruckner requires does no work in the explanation of the welfare-relevance of the desire, Lin claims, especially since Lin’s account and Bruckner’s account are extensionally equivalent. In response, we provide a conceptual analysis of desire based on conceptual role semantics. Our analysis shows the plausibility of and motivation for Bruckner’s account. As well, it shows that the extensional equivalence of the accounts is no accident, but due to what it is to have a desire. Lin has not succeeded in providing an alternative to Bruckner’s account, but merely reformulated it, though in an illuminating way that supports Bruckner’s original case. (shrink)

CHAPTER I INTRODUCTION Relevance was one of the most important concerns in the philosophy of Alfred Schutz. In a sequence of articles dealing with a number ...

This series provides a body of core texts relating to the twin fields of records management and archives. Each volume offers a a detailed and professionally written overview of one or more topics within these fields.

Given an ideal $I$ , let $\mathbb{P}_{I}$ denote the forcing with $I$ -positive sets. We consider models of forcing axioms $MA(\Gamma)$ which also have a normal ideal $I$ with completeness $\omega_{2}$ such that $\mathbb{P}_{I}\in \Gamma$ . Using a bit more than a superhuge cardinal, we produce a model of PFA (proper forcing axiom) which has many ideals on $\omega_{2}$ whose associated forcings are proper; a similar phenomenon is also observed in the standard model of $MA^{+\omega_{1}}(\sigma\mbox{-closed})$ obtained from a supercompact cardinal. (...) Our model of PFA also exhibits weaker versions of ideal properties, which were shown by Foreman and Magidor to be inconsistent with PFA. Along the way, we also show (1) the diagonal reflection principle for internally club sets ( $\mathit{DRP}(IC_{\omega_{1}})$ ) introduced by the author in earlier work is equivalent to a natural weakening of “there is an ideal $I$ such that $\mathbb{P}_{I}$ is proper”; and (2) for many natural classes $\Gamma$ of posets, $MA^{+\omega_{1}}(\Gamma)$ is equivalent to an apparently stronger version which we call $MA^{+\operatorname{Diag}}(\Gamma)$. (shrink)

This collection of essays, though dealing with different topics from section to section, is unified by the idea that, at least in the English-speaking world, ...

Eleonore Stump has argued that the fulfilment of union between God and human beings requires a mode of relatedness that can be compared to joint attention, a phenomenon studied in contemporary experimental psychology. Stump’s account of union, however, is challenged by the fact that mother Teresa, despite her apparent manifestation of the love of God to others, herself experienced an interior ”dark night of the soul’ during which God seemed to be absent and to have rejected her completely. The dark (...) night of the soul poses a problem for Stump’s account, since, if anyone had a union of divine love with God, it would seem that mother Teresa did. Nevertheless, I argue that the isolation and abandonment of mother Teresa’s dark night are contrary to the conditions assumed to be required for joint attention with God. As an alternative to Stump’s account, I suggest that the dark night of the soul might be better understood by reference to a combination of joint attention and blindsight, according to which interpersonal closeness might be realized through a consistent pattern of external actions without, however, a direct awareness of one person by the other. (shrink)

This essay examines two stories in Zhuangzi chapter 6 that provide detailsabout the formal, substantive, and applied features of friendship between daoadepts. Using a template of seven characteristics, dao adept friendship is thencompared with ren adept friendship, described in the Analects and theMencius. It is argued that dao living contains features of friendship that arecomparably robust. As unconventional as dao adept living may be, friendshipis not lacking but integral to such a life.

The problem of eternal separation is the problem of explaining how someone could be happy in heaven while knowing that his beloved is in hell. Some argue that this problem is insoluble, while others try to solve it through the lover, the beloved, or the love between them. I argue that the problem of eternal separation is really three problems, namely, of suffering, separation, and regret. I show that no existing reply solves these problems simultaneously. I then present a new (...) approach through theodicy. I argue that, if we reflect on what it would take to defeat the suffering from losing one’s beloved to hell, a regress emerges, and an adequate solution to the problem of eternal separation is a solution to this regress. I articulate five replies to the regress and evaluate their prospects. The upshot is a roadmap to defending the traditional Christian view of heaven and hell. (shrink)