Biobanks and biospecimen collections are becoming a primary means of delivering personalized diagnostics and tailoring individualized therapeutics. This shift towards precision medicine requires interactions among a variety of stakeholders, including the public, patients, healthcare providers, government, and donors. Very few studies have investigated the role of healthcare students in biobanking and biospecimen donations. The main aims of this study were to evaluate the knowledge of senior healthcare students about biobanks and to assess the students’ willingness to donate biospecimens and the (...) factors influencing their attitudes. A cross-sectional study was conducted among senior healthcare students at King Abdulaziz University, Saudi Arabia. The data were obtained using a self-administered questionnaire in English. In addition to the respondents’ biographical data section, the questionnaire assessed the respondents’ general knowledge about biobanking, the factors influencing their willingness to donate biospecimens to biobanks and their general attitudes towards biomedical research. A total of 597 senior healthcare students were included in the study. The general knowledge score was 3.2 out of 7. Only approximately 44% and 27% of students were aware of the terms “Human Genome Project” and “biobank,” respectively. The majority of the students were willing to donate biospecimens to biobanks. Multiple factors were significantly associated with their willingness to donate, including their perceived general health, past experience with both tissue testing and tissue donation, biobanking knowledge score and biomedical research attitude score. The main reasons for students’ willingness to donate were advancement of medical research and societal benefits, whereas misuse of biospecimens and confidentiality breaches were the main reasons for a reluctance to donate. Despite their strong willingness to donate biospecimens, students exhibited a notable lack of knowledge about biobanking and the HGP. To expedite the transition towards PM, it is highly recommended to enhance healthcare curricula by including more educational and awareness programmes to familiarize students with OMICs technologies in addition to the scope of research and clinical applications. (shrink)

In Beyond Disruption: Technology's Challenge to Governance, experts from academia, media, government, and the military wrestle with understanding the nature of these technologies' threats to our societies and their great potential for our economies. In a series of vivid analyses and colorful commentary from a conference as Stanford University's Hoover Institution, the authors expand upon their first-hand interpretations of what's at stake for the global operating system in the midst of turbulent change. In the dynamic game of world order, it's (...) a primer for decision makers on where the puck is headed. (shrink)

Creating a space for recovery‐focused psychiatric nursing care Within contemporary mental health‐care, power relationships are regularly played out between psychiatric nurses and service users. These power relationships are often imperceptible to the practicing nurse. For instance, in times of distress, service users often turn to or/and ‘construct’ discourses, beliefs and knowledge that are at odds with those which psychiatric nurses rely on to inform them of the mental status of the service user. The psychiatric nurse is in the position to (...) impose knowledge onto service users, usually in concurrence with ‘traditional or bio‐psychiatry’, without realizing or failing to acknowledge that the service user may have an alternative explanation of his/her mental health problems/experiences. In this paper, practice examples, based on the experiences of the four authors (from within and outside of services), are used to illustrate this ‘hidden’ power relationship. The authors use Foucault's ideas about: (i) government; (ii) the knowledge/power nexus and resistance; (iii) and his analytic tool of genealogy to help unravel this paradox within psychiatric nursing practice. The authors also use the emerging discourse of recovery as an alternative (and challenge) to ‘traditional bio‐psychiatry’ and consider the implications for psychiatric nursing practice. (shrink)

Genuine religion always involves the worship of what is genuinely ultimate. Religion, worship, and ultimate reality are thus indissolubly related. The task of reflective thought in this domain is to distinguish what is sound from what is spurious in religion; to characterise the meaning of religious devotion; and to attempt to articulate the nature of the ultimate reality to which men's worship is directed.

The demanding frontier life of My Ántonia or Little House on the Prairie may be long gone, but the idyllic small town still exists as a cherished icon of American community life. Yet sprawl and urban density, rather than small towns and farms, are the predominant features of our modern society, agribusiness and other commercial forces have rapidly taken over family farms and ranches, and even the open spaces we think of as natural retreats only retain the barest façade of (...) their former frontier austerity. The fading communities, social upheaval, and enduring heritage of the Northern Plains are the subject of Jim Dow’s Marking the Land, a stirring photographic tribute to the complex and unyielding landscape of North Dakota. Jim Dow began making pilgrimages to this remote territory in 1981 and, with a commission from the North Dakota Museum of Art, he took photographs of the passing human presence on the land. The simple, stolid pieces of architecture carved out against the Dakota skies—whether the local schoolhouse, car wash, prison, homes, hunting lodge, or churches—evoke in their spare lines and weather-battered frames the stoic and toughened spirit of the people within their walls. Folk art is also an integral part of the landscape in Dow’s visual study, and he examines the subtle evolution of local craftsmanship from homemade sculptures, murals, and carvings to carefully crafted pieces aimed at tourists. Anchoring all of these explorations is the raw and striking landscape of the North Dakota plains. Marking the Land is a moving reflection by a leading American photographer on the state of the Northern Plains today, forcing us all to rethink our conceptions of America’s forgotten frontier. (shrink)

Health professionals, by agreeing to provide care, accept a fiduciary role that entails an obligation to preserve trust. We trust health professionals to be competent, to promote patient interests, and to properly utilize their discretionary power. While some health professionals argue that such activities as secretly screening for drugs or sexually transmitted diseases are necessary to fulfill their fiduciary obligations, these may actually constitute a breach of trust. In this paper, I argue that, in the specific case of Munchausen’s Syndrome (...) by Proxy, covert surveillance is ethically justifiable and does not constitute a breach of trust and an abuse of the fiduciary relationship. (shrink)

The conclusion of this paper will be that e-sports are not sports. I begin by offering a stipulation and a definition. I stipulate that what I have in mind, when thinking about the concept of sport, is ‘Olympic’ sport. And I define an Olympic Sport as an institutionalised, rule-governed contest of human physical skill. The justification for the stipulation lies partly in that it is uncontroversial. Whatever else people might think of as sport, no-one denies that Olympic Sport is sport. (...) This seeks to ensure that those who might wish to dispute my conclusion might stay with the argument at least for as long as possible. Secondly, the justification for the stipulation lies partly in its normativity—I have chosen an Olympic conception of sport just because it seems to me to offer some kind of desirable version of what sport is and might become. Thirdly, I give examples which show how prominent promoters of e-sports agree with my stipulation, as evidenced by their strenuous attempts to comply with it i... (shrink)

This paper suggests and discusses an answer to the following question: What distinguishes causal from non-causal or coincidental co-occurrences? The answer derives from Elizabeth Anscombe’s idea that causality is a highly abstract concept whose meaning derives from our understanding of specific causally productive activities, and from her rejection of the assumption that causality can be informatively understood in terms of actual or counterfactual regularities.Keywords: Elizabeth Anscombe; Causality; Explanation; Inhibition.

This paper presents a counterfactual account of what a mechanism is. Mechanisms consist of parts, the behavior of which conforms to generalizations that are invariant under interventions, and which are modular in the sense that it is possible in principle to change the behavior of one part independently of the others. Each of these features can be captured by the truth of certain counterfactuals.

A new interpretation of the first six books of Augustine's Confessions, emphasizing the importance of Christianity rather than Neoplatonism.

“Small” large cardinal notions in the language of ZFC are those large cardinal notions that are consistent with V = L. Besides their original formulation in classical set theory, we have a variety of analogue notions in systems of admissible set theory, admissible recursion theory, constructive set theory, constructive type theory, explicit mathematics and recursive ordinal notations (as used in proof theory). On the face of it, it is surprising that such distinctively set-theoretical notions have analogues in such disaparate and (...) relatively constructive contexts. There must be an underlying reason why that is possible (and, incidentally, why “large” large cardinal notions have not led to comparable analogues). My long term aim is to develop a common language in which such notions can be expressed and can be interpreted both in their original classical form and in their analogue form in each of these special constructive and semi-constructive cases. This is a program in progress. What is done here, to begin with, is to show how that can be done to a considerable extent in the settings of classical and admissible set theory (and thence, admissible recursion theory). The approach taken here is to expand the language of set theory to allow us to talk about (possibly partial) operations applicable both to sets and to operations and to formulate the large cardinal notions in question in terms of operational closure conditions; at the same time only minimal existence axioms are posited for sets. The resulting system, called Operational Set Theory, is a partial adaptation to the set-theoretical framework of the explicit mathematics framework Feferman (1975). The.. (shrink)

Victor Reppert’s paper (pp. 33-45) supposes that there are objectively indistinguishable properties between possible worlds that resultin the property of intentionality existing in one world but not in another objectively indistinguishable world, differing only in their histories. It is also a supposition of Reppert’s paper that proposed ensembles of purely natural properties that lead to the emergence of intentionality fail to do so, but instead only have referential power on the basis of imputed or projected intentionality from human beings. This (...) brief essay examines this supposition and consequence and attempts to provoke more detailed examination of the underlying issues. (shrink)

The central problem about the relationship between categories and the real order can be stated very simply: the purpose of categorial predication is to yield a set of necessary truths about things within the world, but the universality of these same truths sometimes seems to subordinate the particularity of the real order to the generality of conceptual understanding. As a result, an apparent conflict arises between the real and the logical orders which quite naturally raises a question about how these (...) two separate realms are to be related. In this paper I will examine this question in typically Aristotelian terms, first by discussing a small cluster of passages in Wilfrid Sellars’s challenging paper about Aristotle’s metaphysics, and then by offering my own interpretation of Aristotle’s position about the issue in question. My fundamental purpose in doing this is to establish an intelligible relationship between categories and the real order and to do so by exploring the logical space between an individual thing and the question “What is it?” I am convinced that within this space form and content meet and that we can at least begin to answer our original question about the real and the logical orders by exploring their interconnection. (shrink)

Machamer, Darden, and Craver argue that causal explanations explain effects by describing the operations of the mechanisms which produce them. One of this paper’s aims is to take advantage of neglected resources of Mechanism to rethink the traditional idea that actual or counterfactual natural regularities are essential to the distinction between causal and non-causal co-occurrences, and that generalizations describing natural regularities are essential components of causal explanations. I think that causal productivity and regularity are by no means the same thing, (...) and that the Regularists are mistaken about the roles generalizations play in causal explanation. Humean, logical empiricist, and other Regularist accounts of causal explanation have had the unfortunate effect of distracting philosophers’ from important non-explanatory scientific uses of laws and lesser generalizations which purport to describe natural regularities. My second aim is to characterize some of these uses, illustrating them with examples from neuroscientific research. (shrink)

A startling look at one of this century's most influential philosophers, the book chronicles every stage of Foucault's personal and professional odyssey, from his early interest in dreams to his final preoccupation with sexuality and the nature of personal identity.

Donald Davidson finds folk-psychological explanations anomalous due to the open-ended and constitutive conception of rationality which they employ, and yet monist because they invoke an ontology of only physical events. An eliminative materialist who thinks that the beliefs and desires of folk-psychology are mere pre-scientific fictions cannot accept these claims, but he could accept anomalous monism construed as an analysis, merely, of the ideological and ontological presumptions of folk-psychology. Of course, eliminative materialism is itself only a guess, a marker for (...) material explanations we do not have, but it is made plausible by, inter alia, whatever difficulties we have in interpreting intentional folk-explanations realistically. And surely anomalous monism does require further explanation if it is to be accepted realistically and not dismissed as an analysis of a folk-idiom which is to be construed instrumentally at best. Some further explanation is needed of how beliefs, desires, etc. can form rational patterns which have ‘no echo in physical theory’ and yet those beliefs, desires etc. be physical events. To this end I propose to graft on to anomalous monism a modest version of functionalism. (shrink)

Using Jim Woodward's Counterfactual Dependency account as an example, I argue that causal claims about indeterministic systems cannot be satisfactorily analysed as including counterfactual conditionals among their truth conditions because the counterfactuals such accounts must appeal to need not have truth values. Where this happens, counterfactual analyses transform true causal claims into expressions which are not true.

"We become what we love," states Jim Garrison in Dewey and Eros: Wisdom and Desire in the Art of Teaching. This provocative book represents a major new interpretation of Dewey's education philosophy. It is also an examination of what motivates us to teach and to learn, and begins with the idea of education of eros (i.e., passionate desire)-"the supreme aim of education" as the author puts it-and how that desire results in a practical philosophy that guides us in recognizing what (...) is essentially good or valuable. Garrison weaves these threads of ancient wisdom into a critical analysis of John Dewey's writings that reveal an implicit theory of eros in reasoning, and the central importance of educating eros to seek "the Good." Chapters: Plato's Symposium: Eros, the Beautiful, and the Good • Care, Sympathy, and Community in Classroom Teaching: Feminist Reflections on the Expansive Self • Play-Doh, Poetry, and "Ethereal Things" • The Aesthetic Context of Inquiry and the Teachable Moment • The Education of Eros: Critical and Creative Value Appraisal • Teaching and the Logic of Moral Perception This book can be used in graduate courses in foundations, teacher education, philosophy of education, qualitative research, arts and education, language and literacy, and women and education. Jim Garrison is Professor of Philosophy of Education at Virginia Tech in Blacksburg, VA. He is pastpresident of the John Dewey Society and a winner of the Society's Outstanding Achievement Award. (shrink)

If you are like most people, you’re not sure what Postmodernism is. And if this were like most books on the subject, it probably wouldn’t tell you. Besides what a few grumpy critics claim, Postmodernism is not a bunch of meaningless intellectual mind games. On the contrary, it is a reaction to the most profound spiritual and philosophical crises of our time–the failure of the Enlightenment. Jim Powell takes the position that Postmodernism is a series of “maps” that help people (...) find their way through a changing world. Postmodernism For Beginners features the thoughts of Foucault on power and knowledge, Jameson on mapping the postmodern, Baudrillard on the media, Harvey on time-space compression, Derrida on deconstruction and Deleuze and Guattari on rhizomes. The book also discusses postmodern artifacts such as Madonna, cyberpunk sci-fi, Buddhist ecology and teledildonics. (shrink)

This paper side-steps the question of whether ‘the’ concept of sport exists, or can be usefully analysed. Instead, I try to explain the much more modest aim of exhibition-analysis, which is to seek a description of an actually existing example of some concept of sport internal to a normative position. My example is that of Olympic-sport. I try to set out its logically necessary conditions, which of course are conditioned by its context within a theory that emphasises the values of (...) formal competition, citius-altius-fortius, and excellence in contest, as well as rule-based procedural values related to fairness, justice and equality. In so doing, I readily accept that other kinds of sport can be similarly analysed, and I do not press the value claims of Olympic-sport. Instead, I try to show how Olympic-sport, properly construed, can accommodate the concerns of my critics with regard to sport’s play and game-like characteristics. (shrink)

The main concepts of the free energy (FE) neuroscience developed by Karl Friston and colleagues parallel those of Freud's Project for a Scientific Psychology. In Hobson et al. ( 2014 ) these include an innate virtual reality generator that produces the fictive prior beliefs that Freud described as the primary process. This enables Friston's account to encompass a unified treatment—a complexity theory—of the role of virtual reality in both dreaming and mental disorder. In both accounts the brain operates to minimize (...) FE aroused by sensory impingements—including interoceptive impingements that report compliance with biological imperatives—and constructs a representation/model of the causes of impingement that enables this minimization. In Friston's account (variational) FE equals complexity minus accuracy, and is minimized by increasing accuracy and decreasing complexity. Roughly the brain (or model) increases accuracy together with complexity in waking. This is mediated by consciousness-creating active inference—by which it explains sensory impingements in terms of perceptual experiences of their causes. In sleep it reduces complexity by processes that include both synaptic pruning and consciousness/virtual reality/dreaming in REM. The consciousness-creating active inference that effects complexity-reduction in REM dreaming must operate on FE-arousing data distinct from sensory impingement. The most relevant source is remembered arousals of emotion, both recent and remote, as processed in SWS and REM on “active systems” accounts of memory consolidation/reconsolidation. Freud describes these remembered arousals as condensed in the dreamwork for use in the conscious contents of dreams, and similar condensation can be seen in symptoms. Complexity partly reflects emotional conflict and trauma. This indicates that dreams and symptoms are both produced to reduce complexity in the form of potentially adverse (traumatic or conflicting) arousals of amygdala-related emotions. Mental disorder is thus caused by computational complexity together with mechanisms like synaptic pruning that have evolved for complexity-reduction; and important features of disorder can be understood in these terms. Details of the consilience among Freudian, systems consolidation, and complexity-reduction accounts appear clearly in the analysis of a single fragment of a dream, indicating also how complexity reduction proceeds by a process resembling Bayesian model selection. (shrink)

Vaught identifies the place where religion and philosophy meet--and he does so in constant conversation with Augustine, Hegel, Heidegger and Jaspers. Vaught argues that both religious and philosophical discourse assume one of four modes: figurative, analytical, systematic, and analogical. Any real innovation occurs by moving from one mode of discourse to another. Vaught also explores the relationship among "space," "time," and "place" as well as "mystery," "power," and "structure." Remarkably, Vaught shows how the category of "place" (...) serves as the intersection of both triads. In the end, "place" is the orientation that guides the discussions of Being and God, where philosophy and religion are joined. (shrink)

We discuss the typography of the notation used by Gottlob Frege in his Grundgesetze der Arithmetik.

This reappraisal of the middle section of Augustine's Confessions covers the period of Augustine's conversion to Christianity. The author argues against the prevailing Neoplatonic interpretation of Augustine.