Some natural philosophers in the 17th century believed that they could control their own innards, specifically the animal spirits coursing incessantly through brain and nerves, in order to discipline or harness passion, cognition and action under rational guidance. This chapter addresses the mechanisms thought necessary after Eden for controlling the physiology of passion. The tragedy of human embedding in the body, with its cognitive and moral limitations, was paired with a sense of our confinement in sequential time. I use (...) two strands of 17th-century natural philosophy to exemplify forms of the perceived connection between physiology, memory, and the passions. I deal at length with Cartesian mechanism, and more briefly with Restoration natural philosophy in England. These are fruitful historical domains for connecting cognition and culture, since relations of domination, disruption, or accommodation between present and past are in play for both selves and societies. Despite the difficulty of integrating affect with cognition in theories of brain and mind, the capacity to treat passion and memory together is crucial for future cognitive science to address issues which outsiders care about. (shrink)

Our daily lives unfold continuously, yet our memories are organised into distinct events, situated in a specific context of space and time, and chunked when this context changes (at event boundaries). Previous research showed that this process, termed event segmentation, enhances object-context binding but impairs temporal order memory. Physiologically, peaks in pupil dilation index event segmentation, similar to emotion-induced bursts of autonomic arousal. Emotional arousal also modulates object-context binding and temporal order memory. Yet, these two critical factors have (...) not been systematically studied together. To address this gap, we ran a behavioural experiment using a paradigm validated to study event segmentation and extended it with emotion manipulation. During encoding, we sequentially presented greyscale objects embedded in coloured frames (colour changes defining events), with a neutral or aversive sound. During retrieval, we tested participants’ memory of temporal order memory and object-colour binding. We found opposite effects of emotion and event segmentation on episodic memory. While event segmentation enhanced object-context binding, emotion impaired it. On the contrary, event segmentation impaired temporal order memory, but emotion enhanced it. These findings increase our understanding of episodic memory organisation in laboratory settings, and potentially in real life with perceptual changes and emotion fluctuations constantly interacting. (shrink)

This paper will focus on a famous nineteenth century debate over the physiology of perception between Ewald Hering and Hermann von Helmholtz. This debate is often explained as a contest between empiricism (Helmholtz) and nativism (Hering) about perception. I will argue that this is only part of the picture. Hering was a pioneer of Lamarckian explanations, arguing for an early version of the biogenetic law. Hering explains physical processes, including perception, in terms of ‘organic memory’ that is supported (...) by ‘vital forces’ located throughout the body. Helmholtz, on the other hand, argues that vital forces are in direct conflict with the results he and others proved in the 1840s and 50s on the conservation of force. The battleground of the debate was the interpretation of Johannes Müller’s ‘law of specific nerve energies’, which Hering interpreted in terms of vital forces, and Helmholtz interpreted using a naturalized neo-Kantian approach. In the end, the debate revealed deep fissures in nineteenth century accounts of scientific explanation, as well as in the conception of how physiology, psychology, physics, and philosophy are related. (shrink)

Philosophy and Memory Traces defends two theories of autobiographical memory. One is a bewildering historical view of memories as dynamic patterns in fleeting animal spirits, nervous fluids which rummaged through the pores of brain and body. The other is new connectionism, in which memories are 'stored' only superpositionally, and reconstructed rather than reproduced. Both models, argues John Sutton, depart from static archival metaphors by employing distributed representation, which brings interference and confusion between memory traces. Both raise urgent (...) issues about control of the personal past, and about relations between self and body. Sutton demonstrates the role of bizarre body fluids in moral physiology, as philosophers from Descartes and Locke to Coleridge struggled to control their own innards and impose cognitive discipline on 'the phantasmal chaos of association'. Going on to defend connectionism against Fodor and critics of passive mental representations, he shows how problems of the self are implicated in cognitive science. (shrink)

추모 박물관을 방문한 경험이 있다면, 전시 속 희생자들의 고통에 공감하며 그들과 일종의 유대감을 느끼고, 방문을 마친 후에는 이들의 이야기에 감동을 느낀 경험이 한번쯤 있을 것이다. 이 연구는 방문객들의 감정에 집중하여, 방문객들이 전시에 공감하는 현상과 모순되는 감정, 즉 어째서 고통의 공간인 추모 박물관에서 감동이라는 긍정적인 감정이 촉발되는지에 대해 탐색한다. 따라서 본 연구는 추모 박물관에서 경험되는 감정현상을 두 가지 측면에서 접근한다. 첫째, 다양한 개인의 감정들이 어떻게 “공감된 느낌들(feelings-in-common)”을 통해 한 집단과 유대감을 형성하며 감동을 느끼도록 하는지 살펴보고, 둘째, 어떻게 상반되는 감정들, 즉 슬픈 (...) 감정이 감동으로 바뀌는지와 같은 감정의 움직임에 대해 논의한다. 이를 위한 분석은 문화이론가인 사라 아메드(Sara Ahmed)의 집단적인 감정(collective feeling)에 대한 이론과 감정이론가인 브라이언 마쑤미(Brian Massumi)의 “생리학적 분열(physiologically split)”을 통해 진행한다. 지금까지의 박물관 경험에 대한 논의가 방문객들을 전시가 의도하는 감정의 흐름에 따르는 수동적인 존재로 해석했던 것과는 달리, 본 연구는 지금까지 간과되어왔던 박물관에서 경험되는 모순되는 감정들을 토론에 포함시킴으로써 박물관 경험 뿐 만 아니라 추모 박물관에 대한 이해를 확장시킨다. 따라서 문화이론과 감정이론을 추모 박물관 연구에 접목시킴으로서 본 연구는 박물관 경험을 이해하는 새로운 접근법을 제시하고, 이를 통해 박물관 경험을 재해석함으로써 추모 박물관에 대한 새로운 이해를 도모한다. (shrink)

Social and personality psychology have been criticized for overreliance on potentially biased self-report variables. In well-being science, researchers have called for more “objective” physiological and cognitive measures to evaluate the efficacy of well-being-increasing interventions. This may now be possible with the recent rise of cost-effective, commercially-available wireless physiological recording devices and smartphone-based cognitive testing. We sought to determine whether cognitive and physiological measures, coupled with machine learning methods, could quantify the effects of positive interventions. The current 2-part study used a (...) college sample (N = 245) to contrast the cognitive (memory, attention, construal) and physiological (autonomic, electroencephalogram) effects of engaging in one of two randomly assigned writing activities (i.e., prosocial or “antisocial”). In the prosocial condition, participants described an interaction when they acted in a kind way, then described an interaction when they received kindness. In the “antisocial” condition, participants wrote instead about an interaction when they acted in an unkind way and received unkindness, respectively. Our study replicated previous research on the beneficial effects of recalling prosocial experiences as assessed by self-report. However, we did not detect an effect of the positive or negative activity intervention on either cognitive or physiological measures. More research is needed to investigate under what conditions cognitive and physiological measures may be applicable, but our findings lead us to conclude that they should not be unilaterally favored over the traditional self-report approach. (shrink)

Working memory is a cognitive process that involves maintaining and manipulating information for a short period of time. WM is central to many cognitive processes and declines rapidly with age. Deficits in WM are seen in older adults and in patients with dementia, schizophrenia, major depression, mild cognitive impairment, Alzheimer’s disease, etc. The frontal, parietal, and occipital cortices are significantly involved in WM processing and all brain oscillations are implicated in tackling WM tasks, particularly theta and gamma bands. The (...) theta/gamma neural code hypothesis assumes that retained memory items are recorded via theta-nested gamma cycles. Neuronal oscillations can be manipulated by sensory, invasive- and non-invasive brain stimulations. Transcranial alternating-current stimulation and repetitive transcranial magnetic stimulation are frequency-tuned non-invasive brain stimulation techniques that have been used to entrain endogenous oscillations in a frequency-specific manner. Compared to rTMS, tACS demonstrates superior cost, tolerability, portability, and safety profile, making it an attractive potential tool for improving cognitive performance. Although cognitive research with tACS is still in its infancy compared to rTMS, a number of studies have shown a promising WM enhancement effect, especially in the elderly and patients with cognitive deficits. This review focuses on the various methods and outcomes of tACS on WM in healthy and unhealthy human adults and highlights the established findings, unknowns, challenges, and perspectives important for translating laboratory tACS into realistic clinical settings. This will allow researchers to identify gaps in the literature and develop frequency-tuned tACS protocols with promising safety and efficacy outcomes. Therefore, research efforts in this direction should help to consider frequency-tuned tACS as a non-pharmacological tool of cognitive rehabilitation in physiological aging and patients with cognitive deficits. (shrink)

Bruno Petermann in his The Gestalt Theory and the Problem of Configuration and S. H. MacColl in her A Comparative Study of the Systems of Lewin and Koffka with special reference to Memory Phenomena have shown that the gestalt concept is fundamentally valid but that as a tool of psychological explanation it has been developed with unrecognized inconsistencies and without a successful correlation with physiological facts. And John J. Ryan in his “Volition” has shown that psychology must provide a (...) place for ethical responsibility. The purpose of the present paper is to show that the gestalt concept when conceived in accord with the fundamentals of experimental psychology and of theoretical mathematics and physics: avoids unrecognized inconsistencies; opens the gates to an increasingly refined mensurational correlation between physiological facts and psychological experience; and provides a place within a comprehensive psychology for freedom and purpose, integrated with conditioning, which result in understanding and cooperation in the achievement of ideal purposes. (shrink)

In the first two chapters of his 1925 book Les cadres sociaux de la mémoire (The Social Frameworks of Memory), the French sociologist Maurice Halbwachs (1877-1945) develops a sustained comparison between remembering and dreaming. Engaging in detail with large bodies of contemporary research in psychology, physiology, philosophy, and linguistics, he aims to combat what he calls the ‘surprising’ tendency of ‘psychological treatises that deal with memory’ to treat each of us as ‘an isolated being’ (1925/ 1994, vi) (...) 1. In the course of making a case that memory is deeply situated and social, Halbwachs offers a subtle and challenging treatment of dreams. (shrink)

The emotions that people experience in day-to-day social situations are often mixed emotions. Although autobiographical recall is useful as an emotion induction procedure, it often involves recalling memories associated with a specific discrete emotion. However, real-life emotions occur freely and spontaneously, without such constraints. To understand real-life emotions, the present study examined characteristics of emotions that were elicited by recalling “stressful interpersonal events in daily life” without the targeted evocation of a specific discrete emotion. Assuming generation of mixed and complex (...) emotions, emotional groups with relatively strong correlation of multiple emotions according to surprise, fear, anger, disgust, sadness, and happiness were expected. Seventy-two university students participated in the study. In the emotion induction procedure, participants freely recalled memories as per the instructions on a monitor, and then responded silently to a series of questions concerning any one recalled incident. Assessments of emotional states using emotion scales and another item indicated that validated emotional changes had occurred during the task. Inter-correlations between six emotions demonstrated an emotional group consisting of disgust and anger, which frequently occur as negative interpersonal feelings, and that of fear and sadness. This indicated generation of mixed and complex emotions as experienced in social life. Future studies concerning relationships between these emotions and other factors, including neurophysiological responses, may facilitate further understanding about relationships between mental and physiological processes occurring in daily life. (shrink)

This paper surveys the impact on neuropsychology of Wittgenstein's elucidations of memory. Wittgenstein discredited the storage and imprint models of memory, dissolved the conceptual link between memory and mental images or representations and, upholding the context-sensitivity of memory, made room for a family resemblance concept of memory, where remembering can also amount to doing or saying something. While neuropsychology is still generally under the spell of archival and physiological notions of memory, Wittgenstein's reconceptions can (...) be seen at work in its leading-edge practitioners. However, neuroscientists, generally, are finding memory difficult to demarcate from other cognitive and noncognitive processes, and I suggest this is largely due to their considering automatic responses as part of memory, termed nondeclarative or implicit memory. Taking my lead from Wittgenstein's On Certainty, I argue that there is only remembering where there is also some kind of mnemonic effort or attention, and, therefore, that so-called implicit memory is not memory at all, but a basic, noncognitive certainty. (shrink)

A physiological model for short-term memory (STM) based on dual theta (5–10 Hz) and gamma (20–60 Hz) oscillation was proposed by Lisman and Idiart (1995). In this model a memory is represented by groups of neurons that fire in the same gamma cycle. According to this model, capacity is determined by the number of gamma cycles that occur within the slower theta cycle. We will discuss here the implications of recent reports on theta oscillations recorded in humans performing (...) the Sternberg task. Assuming that the oscillatory memory models are correct, these findings can help determine STM capacity. (shrink)

The “memory of water” was a major international controversy that remains unresolved. Taken seriously or not, this hypothesis leads to logical contradictions in both cases. Indeed, if this hypothesis is held as wrong, then we have to explain how a physiological signal emerged from the background and we have to elucidate a bulk of coherent results. If this hypothesis is held as true, we must explain why these experiments were difficult to reproduce by other teams and why some blind (...) experiments were so disturbing for the expected outcomes. In this article, a third way is proposed by modeling these experiments in a quantum-like probabilistic model. It is interesting to note that this model does not need the hypothesis of the “memory of water” and, nevertheless, all the features of Benveniste’s experiments are taken into account (emergence of a signal from the background, difficulties faced by other teams in terms of reproducibility, disturbances during blind experiments, and apparent “jumps of activity” between samples). In conclusion, it is proposed that the cognitive states of the experimenter exhibited quantum-like properties during Benveniste’s experiments. (shrink)

We understand the workings of the human body as a series of interdependent physiological relationships: muscle interacts with bone as the heart responds to hormones secreted by the brain, all the way down to the inner workings of every cell. To make an organism function, no one component can work alone. In light of this, why is it that the accepted understanding that the physical phenomenon of the mind is attributed only to the brain? In The Embodied Mind, internationally renowned (...) psychiatrist Dr. Thomas R. Verny sets out to redefine our concept of the mind and consciousness. He brilliantly compiles new research that points to the mind's ties to every part of the body. The Embodied Mind collects disparate findings in physiology, genetics, and quantum physics in order to illustrate the mounting evidence that somatic cells, not just neural cells, store memory, inform genetic coding, and adapt to environmental changes-all behaviors that contribute to the mind and consciousness. Cellular memory, Verny shows, is not just an abstraction, but a well-documented scientific fact that will shift our understanding of memory. Verny describes single-celled organisms with no brains demonstrating memory, and points to the remarkable case of a French man who, despite having a brain just a fraction of the typical size, leads a normal life with a family and a job. The Embodied Mind shows how intelligence and consciousness-traits traditionally attributed to the brain alone-also permeate our entire being. Bodily cells and tissues use the same molecular mechanisms for memory as our brain, making our mind more fluid and adaptable than we could have ever imaged. (shrink)

Moderate physiological or emotional arousal induced after learning modulates memory consolidation, helping to distinguish important memories from trivial ones. Yet, the contribution of subjective awareness or interpretation of arousal to this effect is uncertain. Alexithymia, which is an inability to describe or identify one’s emotional and arousal states even though physiological responses to arousal are intact, provides a tool to evaluate the role of arousal interpretation. Participants scoring high and low on alexithymia learned a list of 30 words, followed (...) by immediate recall. Participants then saw either an arousing or neutral video . Memory was tested 24-h later. Physiological response to arousal was comparable between groups, but subjective response to arousal was impaired in high alexithymia. Yet, delayed word recognition was enhanced by arousal regardless of alexithymia status. Thus, subjective response to arousal, i.e., cognitive appraisal, was not necessary for memory modulation to occur. (shrink)

From Aristotle to the present, memory has been grasped as a trace or impression of lost reality – bridging physiological experience and consciousness. Philosophers have vainly sought the nature of this bridge. The present-day physiologizing/naturalizing of consciousness is not resolving their congenital continuity, in which the very existence and practice of life is rooted. We have to change our approach. The Aristotelian congenital ties between memory and temporality, acquire crucial significance in our primogenital ontopoiesis of life. It reveals (...) memory to be the factor that carries this coalescence and the becoming of life itself. This can be the fruit only of the generative springs of life, first phenomenology/philosophy, the ontopoietic logos of life. In this collection we explore memory in the constitution of reality: rememorizing and interpretation, consciousness/action, facts/imagination, history/myths, self-realization/metamorphosis. (shrink)

The work of Hussefl and Freud had common sources in the philosophy, psychology and physiology of the nineteenth century. Herbart, Brentano, Helmholtz, Fechner, Wundt and Mach were among the towering figures in their common background who had influence on their respective work. 1 Although contemporaries who had little concern for the other's professional interest, Husserl and Freud nevertheless struggled with some common problems. One of these is the relationship of sensation to memory and to the experience of time. (...) The concepts of sensation, memory and time were, in fact, artifacts which the empirical methods of nerve-physiology, the psychophysical testing of sensory thresholds, as well as the metaphysics and positivism of the late nineteenth century had left them. (shrink)

The discovery of participation of astrocytes as active elements in glutamatergic tripartite synapses (composed by functional units of two neurons and one astrocyte) has led to the construction of models of cognitive functioning in the human brain, focusing on associative learning, sensory integration, conscious processing and memory formation/retrieval. We have modelled human cognitive functions by means of an ensemble of functional units (tripartite synapses) connected by gap junctions that link distributed astrocytes, allowing the formation of intra- and intercellular calcium (...) waves that putatively mediate large-scale cognitive information processing. The model contains a diagram of molecular mechanisms present in tripartite synapses and contributes to explain the physiological bases of cognitive functions. It can be potentially expanded to explain emotional functions and psychiatric phenomena. (shrink)

This special issue, which includes papers first presented at two workshops on ‘Memory, Mind, and Media’ in Sydney on November 29–30 and December 2–3, 2004, showcases some of the best interdisciplinary work in philosophy and psychology by memory researchers in Australasia (and by one expatriate Australian, Robert Wilson of the University of Alberta). The papers address memory in many contexts: in dance and under hypnosis, in social groups and with siblings, in early childhood and in the laboratory. (...) Memory is taken as a test case for evaluating the optimistic vision of a new kind of cognitive science defended by Andy Clark. Clark (2001:154) argues: Much of what matters about human intelligence is hidden not in the brain, nor in the technology, but in the complex and iterated interactions and collaborations between the two ... The study of these interaction spaces is not easy, and depends both on new multidisciplinary alliances and new forms of modelling and analysis. The pay-off, however, could be spectacular: nothing less than a new kind of cognitive scientific collaboration involving neuroscience, physiology, and social, cultural, and technological studies in about equal measure. So the central motivation is to investigate critically how well the case of memory would fit the extended mind’ thesis put forward by Clark and Chalmers (Clark and Chalmers 1998; Clark 1997, 2006)—according to which mental states and processes can spread across the.. (shrink)

Using a generalized conception of experience, from which all features characteristic for higher animals (such as consciousness and thought) have been removed, allowed relating experience to adaptive processes in lower organisms. The temporal vector character of every current experience, containing as well memories of past experiences as intentions for future activities, can then be found in the adaptive response of cyanobacteria to alterations in phosphate supply, particularly in energetic manifestations of this phenomenon. A possible analogy between adaptive events as the (...) “atomic units” of physiological adaptation and Whitehead's actual occasion of experience is discussed. (shrink)

All five target articles are of high quality and very stimulating for the field. Several factors such as dream report length and NREM/REM differences, may be affected by the waking process (transition from sleep to wakefulness) and the recall process. It is helpful to distinguish between a model for REM sleep regulation and a physiological model for dreaming. A third model accounting for cognitive activity (thought-like dreaming) can also be of value. The postulated adaptive function of dreaming in avoidance learning (...) does not seem very plausible because the two major basic assumptions (specificity of dream content and benefit of negative dreams) are not clearly supported by modern dream research: The critique of studies investigating memory consolidation in REM sleep is justified. Future studies integrating the knowledge of memory processes and sleep research will shed more light on the role of sleep, especially REM sleep in memory consolidation. [Hobson et al.; Nielsen; Revonsuo; Solms; Vertes & Eastman]. (shrink)

The structure of the brain and the nature of evolution suggest that, despite its uniqueness, language likely depends on brain systems that also subserve other functions. The declarative / procedural model claims that the mental lexicon of memorized word- specific knowledge depends on the largely temporal-lobe substrates of declarative memory, which underlies the storage and use of knowledge of facts and events. The mental grammar, which subserves the rule-governed combination of lexical items into complex representations, depends on a distinct (...) neural system. This system, which is composed of a network of specific frontal, basal - ganglia, parietal and cerebellar structures, underlies procedural memory, which supports the learning and execution of motor and cognitive skills, especially those involving sequences. The functions of the two brain systems, together with their anatomical, physiological and biochemical substrates, lead to specific claims and predictions regarding their roles in language. These predictions are compared with those of other neurocognitive models of language. Empirical evidence is presented from neuroimaging studies of normal language processing, and from developmental and adult- onset disorders. It is argued that this evidence supports the DP model. It is additionally proposed that “ language ” disorders, such as specific language impairment and non-fluent and fluent aphasia, may be profitably viewed as impairments primarily affecting one or the other brain system. Overall, the data suggest a new neurocognitive framework for the study of lexicon and grammar. (shrink)

Analgesia and amnesia represent two complimentary pillars of anesthesia directed, respectively, at mitigating the experience of pain and the processes of encoding that experience into memory. These elements are typically combined in modern anesthetic techniques, but some circumstances exist – such as conscious sedation – in which the conditions of amnesia are satisfied while analgesia plays an auxiliary and often incomplete role. These activities reflect a widely held yet underrecognized belief in clinical practice that although pain experiences may be (...) short-lived, their representation in memory and its subsequent effects on thought and emotion can have enduring consequences for patients. In this exploratory article, we delineate phenomenal and abstract ontological categories of pain experience; advance a claim that they are treated by analgesic and amnestic agents, respectively; and describe how each class of experience is uniquely able to bring about individual harm. Beginning with the question of how it can be permissible to allow any preventable experiences or memories of pain, we identify that both phenomenal and abstract pain manifest on a spectrum of severity, each with an enigmatic threshold – unique to circumstance and individual – that determines whether or not pain will translate into harm, and what permissions therefore surround its treatment. Ultimately, we find that there are compelling physiological reasons for the concurrent use of analgesics and amnestics when pain experience exceeds these thresholds, while the treatment of “sub-threshold” experience in either class is a purely ethical imperative to be balanced with considerations of the potential harms posed by the treatments themselves. (shrink)

Working memory performance affects children’s learning. This study examined objective, subjective, and physiological cognitive load while children completed a spatial working memory complex span task. Frist, 80 Taiwanese 11-year-olds who participated in Experiment 1 confirmed the suitability of the materials. Then, 72 Taiwanese 11-year-olds were assigned to high and low complexity groups to participate in Experiment 2 to test the study hypothesis. Children had to recall at the end of a dual-task list and answer two questions regarding the (...) difficulty and mental effort involved in processing and storage. Their pupil diameters were recorded using an eye-tracker. Two-way mixed ANOVA found that the processing requirements and memory load reduced storage and aggravated the subjective CL of storage; the subjective CL of processing was higher under highly complex conditions. Stepwise regression analysis indicated that subjective CL of processing predicted memory performance in low CL conditions, and physiological CL of processing predicted it in high CL conditions. (shrink)

There is considerable evidence that the hippocampal system contributes both to (1) the temporary maintenance of memories and to (2) the processing of a particular type of memory representation. The findings on amnesia suggest that these two distinguishing features of hippocampal memory processing are orthogonal. Together with anatomical and physiological data, the neuropsychological findings support a model of cortico-hippocampal interactions in which the temporal and representational properties of hippocampal memory processing are mediated separately. We propose that neocortical (...) association areas maintain shortterm memories for specific items and events prior to hippocampal processing as well as providing the final repositories of long-term memory. The parahippocampal region supports intermediate-term storage of individual items, and the hippocampal formation itself mediates an organization of memories according to relevant relationships among items. Hippocampal-cortical interactions produce (i) strong and persistent memories for events, including their constituent elements and the relationships among them, and (ii) a capacity to express memories flexibly across a wide range of circumstances. (shrink)

Clinical and experimental evidence suggests that hippocampal damage causes more severe disruption of episodic memories if those memories were encoded in the recent rather than the more distant past. This decrease in sensitivity to damage over time might reflect the formation of multiple traces within the hippocampus itself, or the formation of additional associative links in entorhinal and association cortices. Physiological evidence also supports a two-stage model of the encoding process in which the initial encoding occurs during active waking and (...) deeper consolidation occurs via the formation of additional memory traces during quiet waking or slow-wave sleep. In this article I will describe the changes in cholinergic tone within the hippocampus in different stages of the sleep-wake cycle and will propose that these changes modulate different stages of memory formation. In particular, I will suggest that the high levels of acetylcholine that are present during active waking might set the appropriate dynamics for encoding new information in the hippocampus, by partially suppressing excitatory feedback connections and so facilitating encoding without interference from previously stored information. By contrast, the lower levels of acetylcholine that are present during quiet waking and slow-wave sleep might release this suppression and thereby allow a stronger spread of activity within the hippocampus itself and from the hippocampus to the entorhinal cortex, thus facilitating the process of consolidation of separate memory traces. (shrink)

The possible evolutionary significance of epigenetic memory and codes is a key problem for extended evolutionary synthesis and biosemiotics. In this paper, some less known original works are reviewed which highlight theoretical parallels between current evolutionary epigenetics, on the one hand, and its predecessors in the eco-physiology of higher nervous activity, on the other. Recently, these areas have begun to converge, with first evidence now indicating the possibility of transgenerational epigenetic inheritance of conditional associations in the mammalian nervous (...) system, and related findings in other taxa. This can serve as an interesting example of evolutionary code-making, where the molecular mechanisms underlying arbitrary associations between stimuli involve lasting changes in gene expression that may be transmitted epigenetically across generations, and which in some cases could be further assimilated into the genome over subsequent evolution. Although preliminary, such epigenetic scenarios would also offer an interesting, if so far overlooked parallel to earlier research carried out by one of I.P. Pavlov’s leading students, acad. P.K. Anokhin, and his colleagues, but also by eminent eco-physiologists of the time, several of whom offered arguments for the possibility of unconditional reflexes representing evolutionarily later, specialized, and reduced forms of associative reflexes, from which they may be derived. Although discarded under the growing dominance of modern synthesis, these early epigenetic investigations may deserve renewed attention in the modern context, and if further confirmed, could open essentially new perspectives on the morphofunctional evolution of the nervous system. (shrink)

Philosophy and Memory Traces, the book to which this is the preface, defends two theories of autobiographical memory. One is a bewildering historical view of memories as dynamic patterns in fleeting animal spirits, nervous fluids which rummaged through the pores of brain and body. The other is new connectionism, in which memories are ‘stored’ only superpositionally, and are reconstructed rather than reproduced. Both models depart from static archival metaphors by employing distributed representation, which brings interference and confusion between (...) memory traces. Both raise urgent issues about control of the personal past, and about relations between self and body. The book’s historical argument is anchored by a reinterpretation of Descartes’ dynamic physiology of memory and strange philosophy of the body. English critics of Descartes’ view of memories as motions complained that mechanistic neurophilosophy could not guarantee order in memory, and instead sought techniques for controlling the brain. In a new account of 18th-century philosophers’ fears of confusion in remembering, the author demonstrates the role of bizarre body fluids in moral physiology, as philosophers from Locke to Reid and Coleridge struggled to control their own innards and impose cognitive discipline on ‘the phantasmal chaos of association’. Finally, in a defence of connectionism against Jerry Fodor and against phenomenological and Wittgensteinian critics of passive mental representations, the author shows how problems of the self are implicated in contemporary sciences of mind. The book is an experiment in historical cognitive science, based on a belief that the interdisciplinary study of memory can exemplify the simultaneous attention to brain, body, and culture towards which psychological sciences must aim. (shrink)

Yoga is believed to have beneficial effects on cognition, attenuation of emotional intensity and stress reduction. Previous studies were mainly performed on eastern experienced practitioners or unhealthy subjects undergoing concomitant conventional therapies. Further investigation is needed on the effects of yoga per se, as well as its possible preventive benefits on healthy subjects. We investigated the effects of yoga on memory and psychophysiological parameters related to stress, comparing yoga practice and conventional physical exercises in healthy men . Memory (...) tests, salivary cortisol levels and stress, anxiety, and depression inventories were assessed before and after 6 months of practice. Yoga practitioners showed improvement of the memory performance, as well as improvements in psychophysiological parameters. The present results suggest that regular yoga practice can improve aspects of cognition and quality of life for healthy individuals. An indirect influence of emotional state on cognitive improvement promoted by yoga practice can be proposed. (shrink)

Most theories of memory suggest that when we learn or memorize something, some drepresentation of that something is constructed, stored and later retrieved. This raises questions like:How is information represented?How is it stored?How is it retrieved?Then, how is it used?This paper tries to deal with all these at once. When you get an idea and want to “remember” it, you create a “K‐line” for it. When later activated, the K‐line induces a partial mental state resembling the one that created (...) it. A “partial mental state” is a subset of those mental agencies operating at one moment. This view leads to many ideas about the development, structure and physiology of memory, and about how to implement framelike representations in a distributed processor. (shrink)

The Global Workspace Theory and Information Integration Theory are two of the most currently accepted consciousness models; however, these models do not address many aspects of conscious experience. We compare these models to our previously proposed consciousness model in which the thalamus fills-in processed sensory information from corticothalamic feedback loops within a proposed 3D default space, resulting in the recreation of the internal and external worlds within the mind. This 3D default space is composed of all cells of the body, (...) which communicate via gap junctions and electrical potentials to create this unified space. We use 3D llustrations to explain how both visual and non-visual sensory information may be filled-in within this dynamic space, creating a unified seamless conscious experience. This neural sensory memory space is likely generated by baseline neural oscillatory activity from the default mode network, other salient networks, brainstem, and reticular activating system. (shrink)

Ion channels are transport proteins present in the lipid bilayers of biological membranes. They are involved in many physiological processes, such as the generation of nerve impulses, hormonal secretion, and heartbeat. Conformational changes in the ion channel-forming protein allow the opening or closing of pores to control the ionic flux through the cell membranes. The opening and closing of the ion channel have been classically treated as a random kinetic process, known as a Markov process. Here the time the channel (...) remains in a given state is assumed to be independent of the condition it had in the previous state. More recently, however, several studies have shown that this process is not random but a deterministic one, where both the open and closed dwell-times and the ionic current flowing through the channel are history-dependent. This property is called long memory or long-range correlation. However, there is still much controversy regarding how this memory originates, which region of the channel is responsible for this property, and which models could best reproduce the memory effect. In this article, we provide a review of what is, where it is, its possible origin, and the mathematical methods used to analyze the long-term memory present in the kinetic process of ion channels. (shrink)

After defining various aspects of memory, this paper has sought to outline the phenomenology of memory developed by Erwin Straus and his effort to refute the trace or engram theory of memory storage. We found Straus proposing some major insights : that human experience has its own structure of lived time, that this experience transcends the realm of physical events, and that the suchness of past experiences is preserved, and can be reactivated, in lived time. Straus's approach (...) repudiates the conventional reductionistic wisdom about memory. That wisdom has some powerful support, both ideological and experimental. However, other evidence taken from physiological, neurological, clinical and psychological observations lends weight to Straus's views. The final answer is not in, but it seems plausible that Straus was on the right track toward a framework for human memory. We concluded with a brief broadening out of the Straus framework into the whole realm of lived time or temporality. (shrink)

Ruchkin et al. use brain-activity data from healthy subjects to assess the physiological validity of a cognitive working memory model and to propose modifications. The conclusions drawn from this data are interesting and plausible, but they have limitations. Much of what is known about the neural mechanisms of working memory comes from single neuron recordings in animals, and it is currently not fully understood how these translate to scalp recordings of EEG.

Working memory is the system responsible for maintaining and manipulating information, in the face of ongoing distraction. In turn, WM span is perceived to be an individual-differences construct reflecting the limited capacity of this system. Recently, however, there has been some evidence to suggest that WM capacity can increase through training, raising the possibility that training can functionally alter the neural structures supporting WM. To address the hypothesis that the neural substrates underlying WM are targeted by training, we conducted (...) a meta-analysis of functional magnetic resonance imaging studies of WM training using Activation Likelihood Estimation. Our results demonstrate that WM training is associated exclusively with decreases in blood oxygenation level-dependent responses in clusters within the fronto-parietal system that underlie WM, including the bilateral inferior parietal lobule, middle and superior frontal gyri, and medial frontal gyrus bordering on the cingulate gyrus. We discuss the various psychological and physiological mechanisms that could be responsible for the observed reductions in the BOLD signal in relation to WM training, and consider their implications for the construct of WM span as a limited resource. (shrink)

Heuristics of evolutionary biology dictate that phylogenetically older processes are inherently more stable and resilient to disruption than younger processes. On the grounds that non-declarative behaviour emerged long before declarative behaviour, Reber argues that implicit learning is supported by neural processes that are evolutionarily older than those supporting explicit learning. Reber suggested that implicit learning thus leads to performance that is more robust than explicit learning. Applying this evolutionary framework to motor performance, we examined whether implicit motor learning, relative to (...) explicit motor learning, conferred motor output that was resilient to physiological fatigue and durable over time. In Part One of the study a fatigued state was induced by a double Wingate Anaerobic test protocol. Fatigue had no affect on performance of participants in the implicit condition; whereas, performance of participants in the explicit condition deteriorated significantly. In Part Two of the study a convenience sample of participants was recalled following a one-year hiatus. In both the implicit and the explicit condition retention of performance was seen and, contrary to the findings in Part One, so was resilience to fatigue. The resilient performance in the explicit condition after one year may have resulted from forgetting or from consolidation of declarative knowledge as implicit memories. In either case, implicit processes were left to more effectively support motor performance. (shrink)

The aim of this article is to shed light on Kant’s anthropological theory of memory. I shall contrast physiological studies of memory against Kant’s own study. I suggest some ideas about the relation between memory and time, as long as memory has the power to store and reproduce the temporal configuration of our representations. Moreover, I deal with the problem of personal identity and I suggest that memory contributes to the possibility of this identity from (...) a pragmatic point of view. Finally, I hold that Kant’s pragmatic anthropology does not only provide a description of memory for the human being’s self-knowledge but also for the human being’s self-perfection. Thus, such description discloses not only what the human being is but also what this can become, insofar as it is capable of perfecting itself. (shrink)

Butler’s idea of evolution was developed over the publication of four books, several articles and essays between 1863 and 1890. These publications, although never achieving the success expected by Butler, proposed a psychological elaboration of evolution, called ‘unconscious memory’. This was strongly in contrast with the materialistic approach suggested by Darwin’s natural selection. Starting with a historical introduction, this paper aspires to ascertain the logic, meaning and significance of Butler’s idea of ‘unconscious memory’ in the post-Darwinian physiological and (...) psychological Pan-European discussion. Particular attention is devoted to demonstrating that Butler was not only a populariser of science but also an active protagonist in the late Victorian psychological debate. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ideas in the Brain: The Localization of Memory Traces in the Eighteenth CenturyTimo KaitaroPlato suggests in the Theaetetus that we imagine a piece of wax in our soul, a gift from the goddess of Memory. We are able to remember things when our perceptions or thoughts imprint a trace upon this piece of wax, in the same manner as a seal is stamped on wax. Plato uses (...) this metaphor to explain the errors which arise when we mistake something for something else: we connect the perception of an object with the trace belonging to another. The metaphor can also be used in explaining differences in people’s mnestic capacities: rapid learning and forgetting correspond to soft wax, impure wax results in muddled traces, etc.1 If we locate the traces in the brain instead of in the soul, Plato’s metaphor gains consistency and turns into a testable hypothesis. This move was already made by Quintilian.2So, the metaphor of memory as traces in the brain is evidently not a modern invention. This is easy to understand. To frame the hypothesis one needs only to reflect on how we use objects outside our brains for mnemonic purposes. We conserve ideas by tracing or printing letters and words on paper. We are also able to conserve images in drawings, paintings and prints. What could be more natural than to think of memory as the formation of traces in the brain? The development of even better information storage techniques in the form of pictures, symbols, and signs provides the metaphor extra plausibility. Plato’s seal allows us to imagine the imprint of a person’s likeness, but modern techniques of information storage and retrieval make it even easier to imagine memory in general as the formation of material traces.Explaining memory in terms of material traces could, of course, be taken [End Page 301] to mean that the formation of material traces in the brain is merely a necessary condition of memory. But one could also take a more reductionistic stance which identifies memory with the formation of material traces. Furthermore, one could identify specific mental items (sensations, ideas, memories) with specific physiological events or anatomical entities in the brain. This seems especially plausible if we imagine that the traces in the brain are as discrete and separate as ideas or memories are in our minds. Since the traces we form or print on paper consist of discrete letters and words, the thought that the traces in the brain are equally discrete and separate comes easily. Plato, in fact, made separateness a condition for the memory to work properly: it is not easy to read signs printed on one another.3 Of course, no traces are actually visible in the brain. But they are easy to imagine, as it is to imagine explanations of psychological phenomena, such as association, based on these traces.At the end of the seventeenth century, explanations of mental phenomena referring to material traces in the brain were used by writers, from Platonists to materialists, who supported widely different theories about the nature of the human mind.4 In fact, as I will show later in this paper, the question of the possible identity of mental entities, like ideas or sensations, with material entities or traces in the brain is relatively independent of the question of the existence of an immaterial soul. Or rather, if there is a systematic connection between the answers proposed to these two questions in the eighteenth century, it is not the connection one would expect. Nowadays we often tend to think of a prototypical materialist as someone who makes radical reductionistic claims about the identity of mental phenomena with brain states. We also tend to think of the eighteenth-century French materialists as “mechanistic.”5 In view of this reputation, it may come as a surprise to find that some eighteenth-century materialists, notably Denis Diderot, were in fact consistent anti-reductionists and opposed to mechanical or mechanistic explanations of the mental.6 In fact, the epithet “mechanistic” is misleading even when applied to the philosopher who is traditionally presented as the paradigmatic example of a “mechanistic materialist,” Julien Offray... (shrink)

Temporal binding via 40-Hz synchronization of neuronal discharges in sensory cortices has been hypothesized to be a necessary condition for the rapid selection of perceptually relevant information for further processing in working memory. Binocular rivalry experiments have shown that late stage visual processing associated with the recognition of a stimulus object is highly correlated with discharge rates in inferotemporal cortex. The hippocampus is the primary recipient of inferotemporal outputs and is known to be the substrate for the consolidation of (...) working memories to long-term, episodic memories. The prefrontal cortex, on the other hand, is widely thought to mediate working memory processes, per se. This article reviews accumulated evidence for the role of a subcortical matrix in linking frontal and hippocampal systems to select and ''stream'' conscious episodes across time (hundreds of milliseconds to several seconds). ''Streaming'' is hypothesized to be mediated by the selective gating of reentrant flows of information between these cortical systems and the subcortical matrix. The physiological mechanism proposed for this temporally extended form of binding is synchronous oscillations in the slower EEG spectrum (< 8 Hz). (shrink)

In this paper we criticize the commonly accepted theory of memory, and offer an alternative. According to the traditional view, memory is a stored mental representation of things past. We show, through an analysis of a single act of recognition, the logical oddities to which this view leads. Since, however, these are generally ignored, we also consider those characteristics of the traditional view which apparently make it attractive to those who hold it, namely its consonance with the commonly (...) held conception of time, its explanation for the fallibility of memory, and its way of making behavior predictable. We then present the alternative view, the direct realist theory. According to it, there is no such thing as a stored mental representation. The theory redefines memory as the perception of sequential structure, and in so doing successfully treats of the fallibility of memory and the necessity for making behavior predictable. Moreover, and perhaps most importantly, it does not lead to the logical difficulties of the traditional theory. (shrink)

Nostalgia as one of the complex emotions has been challenged over the past few decades due to its psychological and physiological functions. The present experiment investigates the effect of recalling nostalgic memories on amelioration of homeostatic and health state of people with cardiovascular disease. Method: The participants were 30 patients who were hospitalized for angiography procedure. The research was based on an experimental design with randomized and post-test groups. The instruments used included a thermometer with ° C, a checkout manipulation (...) test, a blood pressure monitor, an ice container and a manual timer, a pain intensity perception scale and Batcho’s nostalgia questionnaire. Results: The results showed that there was a significant difference between the two groups in perceived temperature, the resilience in the face of pain, and the perceived pain. The experimental group perceived higher temperature and showed greater resilience in the face of pain and also lower pain intensity was reported. There was no significant difference in blood pressure between the two groups. Conclusion: The results of this study provide significant evidence for the embodiment emotions hypothesis and positive role of Nostalgia in psychological and physiological homeostatic. Further practical implications of results and suggestions for future research were considered. (shrink)

Type 2 diabetes has been considered a public health threat due to its growing prevalence, particularly in the older population. It is important to know the effects of psychosocial stress and its potential consequences for some basic cognitive processes that are important in daily life. Currently, there is very little information about how people with T2D face acute psychosocial stressors, and even less about how their response affects working memory, which is essential for their functionality and independence. Our aim (...) was to characterize the response to an acute laboratory psychosocial stressor and its effects on WM in older people with T2D. Fifty participants with T2D from 52 to 77 years old were randomly assigned to a stress or control condition. Mood and physiological responses to tasks were measured. In addition, participants completed a WM test before and after the stress or control task. Our results showed that the TSST elicited higher negative affect and greater C and sAA responses than the control task. No significant differences in WM were observed depending on the exposure to stress or the control task. Finally, participants who showed higher C and sAA responses to the stressor had lower WM performance. Our results indicate that medically treated older adults with T2D show clear, typical mood and physiological responses to an acute psychosocial stressor. Finally, the lack of acute psychosocial stress effects on WM suggests that it could be related to aging and not to this disease, at least when T2D is adequately treated. (shrink)

Advances in molecular, genetic, and cell biological techniques have allowed neuroscientists to delve into the cellular machinery of learning and memory. The calcium and calmodulin-dependent kinase type II (CaMKII) is one of the best candidates for being a molecular component of the learning and memory machinery in the mammalian brain. It is present in abundance at synapses and its enzymatic properties and responsiveness to intracellular Ca2+ fit a model whereby Ca2+ currents activate the kinase and lead to changes (...) in synaptic efficacy. Indeed, such plastic properties of synapses are thought to be important for memory formation. Genetic analysis of the alpha isoform of CaMKII in mice support the hypothesis that CaMKII signaling is required to initiate the formation of new spatial memories in the hippocampus. CaMKII is also required for the correct induction of long-term potentiation (LTP) in the hippocampus, consistent with the widely held belief that LTP is a mechanism for learning and memory. Recent cell biological, genetic, and physiological analyses suggest that one of the cellular explanations for LTP and CaMKII function might be the trafficking of AMPA-type receptors to synapses in response to neural activity. BioEssays 24:223–233, 2002. © 2002 Wiley Periodicals, Inc.; DOI 10.1002/bies.10057. (shrink)

We criticize the synaptic theory of long-term memory and the inappropriate usage of physical notions such as in motor control theories. Motor control and motor memory hypotheses should be based on explicitly specified hypothetical control variables that are sound from both physiological and physical perspectives. [HOUK et al.; SMITH; THACH].

Dreaming in sleep must depend on the activity of the brain as does cognition and memory in wakefulness. Yet our understanding of the physiological subtleties of state differences may still be too primitive to guide theories adequately in these areas. One can state nonetheless unequivocally that the brain in REM is poorly equipped to practice for eventualities of wakefulness through dreaming, or for consolidating into memory the complex experiences of that state. [Hobson et al., Nielsen, Solms, Vertes & (...) Eastman, Revonsuo]. (shrink)