Genetic testing can be used to determine if unexplained fractures in children could have resulted from a predisposition to bone fractures, e.g., osteogenesis imperfecta. However, uncertainty is introduced if a variant of unknown significance is identified. Proper interpretation of VUS in these situations is critical because of its influence on clinical care and in court rulings. This study sought to understand how VUS are interpreted and used by practitioners when there is a differential diagnosis including both osteogenesis imperfecta and non-accidental (...) injury.A 15-question survey was emailed to physicians who requested analysis of two genes, COL1A1 and COL1A2, from the University of Washington from 2005-2013 for patient cases involving suspicion of child abuse.Among the 89 participants, responses differed about when genetic testing should be ordered for osteogenesis imperfecta, who should be consulted about utilization of VUS test results, follow-up procedures, and who should receive the VUS results.There are no clear guidelines for how to interpret and follow up on VUS. In the legal setting, misinterpreted VUS could lead to unintended consequences and deleterious ramifications for family members. The need for better practice guidelines to help promote more equitable handling of these sensitive legal cases is clear. (shrink)

This paper explores possible connections between gender and the willingness to tolerate unethical academic behavior. Data from a sample of 285 accounting majors at four public institutions reveal that females are less tolerant than males when questioned about academic misconduct. Statistically significant differences were found for 17 of 23 questionable activities. Furthermore, females were found to be less cynical and less often involved in academic dishonesty. Overall, the results support the finding of Betz et al. (1989) that the gender socialization (...) approach dominates the structural approach. (shrink)

Mind wandering is typically operationalized as task-unrelated thought. Some argue for the need to distinguish between unintentional and intentional mind wandering, where an agent voluntarily shifts attention from task-related to task-unrelated thoughts. We reveal an inconsistency between the standard, task-unrelated thought definition of mind wandering and the occurrence of intentional mind wandering (together with plausible assumptions about tasks and intentions). This suggests that either the standard definition of mind wandering should be rejected or that intentional mind wandering is an incoherent (...) category. Solving this puzzle is critical for advancing theoretical frameworks of mind wandering. (shrink)

From this post-reflective point of view, the book argues for an intimate relationship between cognition, sensorimotor embodiment, and the integrative character ...

We sometimes fail unwittingly to do things that we ought to do. And we are, from time to time, culpable for these unwitting omissions. We provide an outline of a theory of responsibility for unwitting omissions. We emphasize two distinctive ideas: (i) many unwitting omissions can be understood as failures of appropriate vigilance, and; (ii) the sort of self-control implicated in these failures of appropriate vigilance is valuable. We argue that the norms that govern vigilance and the value of self-control (...) explain culpability for unwitting omissions. (shrink)

This work represents Murray Bookchin's riposte to the antihumanism, mysticism and antirationalism which are influencing many people's attitudes to environmental problems. Bookchin offers a critique of, among others, social Darwinists, deep ecologists, new agers, technophobes, Foucault, Derrida and Baudrillard.

Confabulation is typically understood to be dysfunctional. But this understanding neglects the phenomenon’s potential benefits. In fact, we think that the benefits of non-clinical confabulation provide a better foundation for a general account of confabulation. In this paper, we start from these benefits to develop a social teleological account of confabulation. Central to our account is the idea that confabulation manifests a kind of willful ignorance. By understanding confabulation in this way, we can provide principled explanations for the difference between (...) clinical and non-clinical cases of confabulation and the extent to which confabulation is rational. (shrink)

(Re)presentations of evil in media, philosophy and literature -- The dangerous ones : when evil was a woman -- Space/times of evil : political life and social worlds.

One popular theory of moral responsibility locates responsible agency in exercises of control. These control-based theories often appeal to tracing to explain responsibility in cases where some agent is intuitively responsible for bringing about some outcome despite lacking direct control over that outcome’s obtaining. Some question whether control-based theories are committed to utilizing tracing to explain responsibility in certain cases. I argue that reflecting on certain kinds of negligence shows that tracing plays an ineliminable role in any adequate control-based theory (...) of responsibility. (shrink)

The corporate sustainability, and responsibility, movement has considerable implications for and impact on the discipline of brand management. It creates pressures to which the discipline must adjust, and new growth opportunities for it to enjoy.In Maio''s view, "brand" permeates all aspects of the corporation and therefore the values of the brand can serve as an effective touchstone for all corporate behaviours: in the Boardroom, in financial markets, in negotiations with employees, in customer interactions, in dialogue with other stakeholders. Moreover, most (...) corporations already have "plumbing" in place (the organizational substructures and processes to manage their brand), that can serve as effective conduits for nurturing values-driven behaviours and measuring them. (shrink)

" With this succinct formulation, Murray Bookchin launches his most ambitious work, The Ecology of Freedom.

Using philosophical guidelines--and applying these guidelines throughout a patient's lifespan--this text assists readers in making ethically sound choices in nursing. It explores both traditional and contemporary ethical theories and acknowledges changing trends in the health field, incorporating issues such as managed care. Includes clinical case studies within each chapter. Incorporates a new organization in Part Two, in three sections entitled "Developmental Highlights," "Issues and Problems," and "Morally Reasoned Nursing Interventions." Provides new "What if?" questions throughout to help apply theory to (...) real events. Offers extensive analysis of euthanasia and assisted suicide. Includes thorough coverage of the HIV/AIDS epidemic and its moral complexities. Discusses organ transplantation and experimental medical treatments in ethical context. Ideal for practicing nurses looking for a reference on professional ethics. (shrink)

Addresses the meaning of rationality. The author argues that common conceptions of this notion are founded upon dubious myths of reason; and that systematic approaches to rational understanding are inherently limited by denying the cognitive value of myth and metaphor.

The object of this paper is to enquire how far we can trace in the works of Horace the use of the plural forms of the first person which have been pointed out by Professor R. S. Conway in his essay on The Use of the Singular nos in Cicero's Letters , from which it appeared that the idiom throws valuable light upon the inner workings of Cicero's mind.

In _The Global and the Local: An Environmental Ethics Casebook_, Dale Murray presents fifty-one compelling case studies. By interweaving theoretical considerations into case studies, Murray illuminates a comprehensive range of the most pressing environmental issues facing our biosphere.

A challenging new work of cultural and political theory rethinks the concept of hegemony.

Provides a comprehensive overview and introduction to the Routledge Handbook of Propositions.

This volume assesses the ethical, quantitative, and qualitative questions posed by the current financing of biomedical research.

This edition identifies and strengthens critical thinking skills in nursing, emphasizing the value of applying systematic reasoning to clarify conflicts experienced by nurses, resolve controversial moral issues, and make sound judgments. It also helps strengthen intellectual and scientific acuity through the use of reason and logic, and examines the use of argument in nursing. Advanced nursing students.

A qualitative analysis of societal silences, demonstrating how the unsaid directs social action and shapes individual and collective lives.

In his new introduction to this current edition of this classic in the field originally published in 1982 (Humanities Press), Hoppe (economics, U. of Nevada, Las Vegas--as was the late author) extols Rothbard's marriage of the "value-free" science of economics with the normative enterprise of ethics and their offspring: libertarianism. Discussion areas are: natural law, a theory of liberty, the state vs. liberty, modern alternative theories of liberty, and toward a theory of strategy for liberty. Annotation copyrighted by Book News, (...) Inc., Portland, OR. (shrink)

According to the attentional resources account, mind wandering (or “task-unrelated thought”) is thought to compete with a focal task for attentional resources. Here, we tested two key predictions of this account: First, that mind wandering should not interfere with performance on a task that does not require attentional resources; second, that as task requirements become automatized, performance should improve and depth of mind wandering should increase. Here, we used a serial reaction time task with implicit- and explicit-learning groups to test (...) these predictions. Providing novel evidence for the attentional resource account’s first prediction, results indicated that depth of mind wandering was negatively associated with learning in the explicit, but not the implicit, group, indicating that mind wandering is associated with impaired explicit, but not implicit, learning. Corroborating the attention resource account’s second prediction, we also found that, overall, performance improved while at the same time depth of mind wandering increased. From an implicit learning perspective, these results are consistent with the claim that explicit learning is impaired under attentional load, but implicit learning is not. (shrink)

Roots present first‐hand accounts of discoveries in genetics, molecular biology, cellular biology, and developmental biology. In the following article, Murray L. Barr describes the background to and the events surrounding the discovery of the cytogenetic evidence for inactive × chromosomes in mammals. In the accompanying article, Michael W. McBurney reviews current molecular knowledge about the inactive × and proposes a hypothesis to explain the phenomenon.

John Calvin's teaching that Christians should pray “for all people who dwell on earth” is based on his interpretation of 1 Tim 2:1–2 and related to the Lords Prayer. It is also illustrated clearly in his daily practice of leading public worship.