Results for 'Henry Beecher'

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  1.  28
    Research and the individual.Henry Knowles Beecher - 1970 - Boston,: Little, Brown.
  2. Medical research and the individual.Henry K. Beecher - 1968 - In Edward Shils (ed.), Life or death: ethics and options. Portland, Or.,: Reed College. pp. 133.
     
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  3.  20
    Henry Beecher and Consent to Research: a critical re-examination.Franklin G. Miller - 2016 - Perspectives in Biology and Medicine 59 (1):78-94.
    Henry Beecher was a distinguished professor of anesthesia and clinical investigator at Harvard Medical School. He became an iconic figure in bioethics, best known for his 1966 article describing 22 examples of unethical clinical research. This is one of the most frequently cited articles on ethics in the medical literature. Indeed, it may be seen as marking a watershed in the moral climate of medical research. In his history of bioethics, Albert Jonsen characterized Beecher as one of (...)
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  4.  55
    Physical Manipulation of the Brain.Henry K. Beecher, Edgar A. Bering, Donald T. Chalkley, José M. R. Delgado, Vernon H. Mark, Karl H. Pribram, Gardner C. Quarton, Theodore B. Rasmussen, William Beecher Scoville, William H. Sweet, Daniel Callahan, K. Danner Clouser, Harold Edgar, Rudolph Ehrensing, James R. Gavin, Willard Gaylin, Bruce Hilton, Perry London, Robert Michels, Robert Neville, Ann Orlov, Herbert G. Vaughan, Paul Weiss & Jose M. R. Delgado - 1973 - Hastings Center Report 3 (Special Supplement):1.
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  5.  35
    Henry Beecher’s Contributions to the Ethics of Clinical Research.Robert M. Veatch - 2016 - Perspectives in Biology and Medicine 59 (1):3-17.
    When I arrived at Harvard as an incoming graduate student in the fall of 1964, I soon received a telephone call from a gentleman who introduced himself as Henry Beecher. I was in the process of shifting my graduate studies from research neuropharmacology to the study of ethics. Robert Featherstone, the head of the Department of Pharmacology at the University of California Medical Center, San Francisco, where I had been studying, was a specialist in anesthesiology and knew (...) Beecher, who was also working in anesthesiology, well. He had contacted Beecher, alerting him to the fact that a new graduate student was arriving and that it appeared that the two of us had much in common. The phone call from Beecher... (shrink)
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  6.  49
    Acid Brothers: Henry Beecher, Timothy Leary, and the psychedelic of the century.Jonathan D. Moreno - 2016 - Perspectives in Biology and Medicine 59 (1):107-121.
    Henry Knowles Beecher, an icon of human research ethics, and Timothy Francis Leary, a guru of the counterculture, are bound together in history by the synthetic hallucinogen lysergic acid diethylamide. Beecher was a U.S. Army Lieutenant Colonel who received five battle stars, was inducted into the Legion of Merit, held the first endowed chair in his discipline, wrote at least three path-breaking papers, and is honored by two prestigious ethics awards in his name. Leary was a West (...)
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  7.  22
    Expanding the Social Status of "Corpse" to the Severely Comatose: Henry Beecher and the Harvard Brain Death Committee.Michael Nair-Collins - 2022 - Perspectives in Biology and Medicine 65 (1):41-58.
  8.  22
    Henry K. Beecher and the Oversight of Research in Children.John Lantos - 2016 - Perspectives in Biology and Medicine 59 (1):95-106.
    Henry K. Beecher’s famous 1966 article on ethically problematic medical research was a pivot point. It came at the end of two decades of soul-searching among researchers and philosophers. It ushered in an era of legislation and regulation to address the complex issues that had been extensively discussed by Beecher and others. That soul-searching began with the Nuremberg trials and the disturbing recognition of how far the Nazi doctors had strayed from professional ethical norms. It led, eventually, (...)
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  9.  11
    Beecher Reconsidered.Jonathan D. Moreno - 2019 - Hastings Center Report 49 (3):3-3.
    In 1962, Harvard professor of anesthesiology Henry Beecher wrote to Senator Estes Kefauver about certain additions to the federal Food and Drug Act then being considered. According to The Antibiotic Era, the Maryland congressman Samuel Friedel had introduced language that would require informed consent in clinical research. Beecher joined a number of other distinguished medical scientists warning that such a requirement would “cripple” American medical research. A year before, Beecher had protested the U.S. Army's inclusion of (...)
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  10.  19
    Henry Knowles Beecher, Jay Katz, and the Transformation of Research with Human Beings.Alexander Morgan Capron - 2016 - Perspectives in Biology and Medicine 59 (1):55-77.
    The modern history of experimentation with human beings is notable for its ethical lacunae. In 1865, in his great work, An Introduction to the Study of Experimental Medicine, Dr. Claude Bernard, the French physician who first established the use of the scientific method in medicine, echoed the earlier injunctions of physician-moralist Moses Maimonides in counseling his fellow physicians not to treat their patients solely as a means of advancing knowledge. Yet such cautions had no apparent effect on the physicians who, (...)
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  11.  18
    Beecher as Clinical Investigator: Pain and the Placebo Effect.Fabrizio Benedetti - 2016 - Perspectives in Biology and Medicine 59 (1):37-45.
    To be both a clinician and a scientist—what is usually called a clinician scientist or clinical investigator—is easy neither from an ethical nor from a methodological standpoint. On the one hand, it requires care, cure of the patients, and good ethical practice. On the other, excellent skills in experimental design and data analysis are necessary. In addition, the correct choice of a disease as a model to be studied is very often hampered by the obvious ethical constraints of working with (...)
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  12.  24
    Beecher Dépassé_: _Fifty Years of Determining Death, Legally.Alexander M. Capron - 2018 - Hastings Center Report 48 (S4):14-18.
    Five decades ago, Henry Knowles Beecher, a renowned professor of research anesthesiology, sought to solve a problem created by modern medicine. The solution proposed by Beecher and his colleagues on the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death proved very influential.1 Indeed, other contemporaneous medical developments magnified its significance yet also made the solution it offered somewhat problematic. As we mark this fiftieth anniversary, at a time when concerns about (...)
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  13.  18
    “Ethics and Clinical Research” Revisited: A Tribute to Henry K. Beecher.Jay Katz - 1993 - Hastings Center Report 23 (5):31-39.
    The doctrine of informed consent, borrowed from the law of torts, cannot be readily transplanted into therapeutic settings. The broader, as yet unrealized, idea of informed consent, which suggests that parties must make decisions jointly, should guide interactions between physicians and patients or investigators and subjects.
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  14.  17
    At the Juncture of Theory and Practice: Remarks on Receiving the Henry Knowles Beecher Award.Sissela Bok - 1996 - Hastings Center Report 26 (3):5-8.
  15.  16
    At the Juncture of Theory and Practice: Remarks on Receiving the Henry Knowles Beecher Award.Sissela Bok - 2012 - Hastings Center Report 26 (3):5-8.
  16.  36
    When, How, and Why Did “Pain” Become Subjective?Charles Djordjevic - 2023 - Philosophy of Medicine 4 (1).
    The pain-assessment literature often claims that pain is subjective. However, the meaning and implications of this claim are left to the reader’s imagination. This paper attempts to make sense of the claim and its problems from the history and philosophy of science perspective. It examines the work of Henry Beecher, the first person to operationalize “pain” in terms of subjective measurements. First, I reconstruct Beecher’s operationalization of “pain.” Next, I argue this operationalization fails. Third, I salvage (...)’s insights by repositioning them in an intersubjective account. Finally, I connect these insights to current pain-assessment approaches, showing that they enrich each other. (shrink)
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  17.  17
    Medicine Medicine at Harvard: the First 300 Years. By Henry K. Beecher and Mark D. Altschule. Hanover, New Hampshire: University Press of New England. 1977. Pp. xv + 587. $27.50. [REVIEW]Kenneth Ludmerer - 1980 - British Journal for the History of Science 13 (1):64-65.
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  18.  51
    The Role of the Virtuous Investigator in Protecting Human Research Subjects.Christine Grady & Anthony S. Fauci - 2016 - Perspectives in Biology and Medicine 59 (1):122-131.
    Dr. Henry Beecher, a renowned Harvard Medical School anesthesiologist, sent shock waves through the medical research community and the lay press when he described 22 examples of “unethical or questionably ethical studies” by reputable researchers at major institutions in his now well-known 1966 New England Journal of Medicine article. Beecher concluded this exposé by noting: “The ethical approach to experimentation in man has several components: two are more important than the others, the first being informed consent.... Secondly, (...)
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  19.  35
    Brain Death: A Conclusion in Search of a Justification.D. Alan Shewmon - 2018 - Hastings Center Report 48 (S4):22-25.
    At its inception, “brain death” was proposed not as a coherent concept but as a useful one. The 1968 Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death gave no reason that “irreversible coma” should be death itself, but simply asserted that the time had come for it to be declared so. Subsequent writings by chairman Henry Beecher made clear that, to him at least, death was essentially a social construct, and society (...)
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  20.  19
    Would a Reasonable Person Now Accept the 1968 Harvard Brain Death Report? A Short History of Brain Death.Robert M. Veatch - 2018 - Hastings Center Report 48 (S4):6-9.
    When The Ad Hoc Committee of Harvard Medical School to Examine the Definition of Brain Death began meeting in 1967, I was a graduate student, with committee member Ralph Potter and committee chair Henry Beecher as my mentors. The question of when to stop life support on a severely compromised patient was not clearly differentiated from the question of when someone was dead. A serious clinical problem arose when physicians realized that a patient's condition was hopeless but life (...)
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  21.  30
    Open-Label Placebo: Reflections on a Research Agenda.Ted J. Kaptchuk - 2018 - Perspectives in Biology and Medicine 61 (3):311-334.
    Until recently, the medical community assumed that placebos required either concealment in randomized controlled trials or deception in clinical practice to elicit placebo effects. Henry Beecher emphasized this orthodoxy, when he stated that placebo pills only work "as long as it is not detected as a placebo by the subject or the observer" and therefore, patients "believe it [is a drug] and consequently the expected results occurs". The time was ripe for such ideas: Norman Vincent Peale's The Power (...)
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  22.  11
    The Center's Highest Award.Bradford H. Gray & Mildred Z. Solomon - 2021 - Hastings Center Report 51 (4):inside_front_cover-inside_front_.
    Prompted by a 2019 essay by Jonathan Moreno in the Hastings Center Report, the Center's board of directors undertook a careful examination of the name of its preeiminent award, the Henry Knowles Beecher Award, which has been given to twenty‐nine individuals who have made lifetime contributions to bioethics. citing new research that revealed that Beecher's earlier experimentation on drugs had involved nonconsenting adults, Moreno urged the Center to reevaluate honoring Beecher through this award. After reviewing the (...)
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  23.  44
    Clinical Trials Without Consent?Scott Y. H. Kim - 2016 - Perspectives in Biology and Medicine 59 (1):132-146.
    The routine practice of clinical research involving patient-subjects without informed consent prior to 1966 unquestionably was unethical. Does it follow that all clinical research involving competent adult patient-subjects is unethical without informed consent?In his landmark 1966 paper, Henry Beecher noted that of the 50 example studies he had originally compiled in preparation for that paper, only two even mentioned consent, and he observed further that mention of consent is “meaningless unless one knows how fully the patient was informed”. (...)
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  24.  16
    Ethicizing history. Bioethical representations of Nazi medicine.Mathias Schütz & Harold Braswell - 2023 - Bioethics 37 (6):581-590.
    The article presents and analyzes different approaches of U.S. bioethicists in comprehending the Nazi medical crimes after 1945. The account is divided into two sections: one dealing with discussions on research ethics and the Nuremberg Code up until the 1970s and the other ranging from the 1970s to the present and highlighting bioethics' engagement with Nazi analogies. The portrayal of different bioethical scholars, institutions, and documents—most notably Henry K. Beecher, Jay Katz, the Belmont Report, the Hastings Center, Arthur (...)
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  25.  14
    Commentary: Research Ethics after World War II: The Insular Culture of Biomedicine.Lara Freidenfelds & Allan M. Brandt - 1996 - Kennedy Institute of Ethics Journal 6 (3):239-243.
    In lieu of an abstract, here is a brief excerpt of the content:Research Ethics after World War II: The Insular Culture of BiomedicineAllan M. Brandt (bio) and Lara Freidenfelds (bio)Human subjects research in the United States has only recently emerged as an important area of historical investigation. Over the last quarter century, scholars have begun the process of grounding within an historical context both the complex relationship between researchers and subjects and the processes by which biomedical knowledge is produced. Their (...)
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  26.  6
    Editors' Introduction.Franklin G. Miller & John Lantos - 2016 - Perspectives in Biology and Medicine 59 (1):1-1.
    On June 16, 1966, the New England Journal of Medicine published “Ethics and Clinical Research” by Henry K. Beecher. Beecher’s account of 22 examples of unethical contemporary clinical research shook up the medical profession and helped pave the way for U.S. federal regulation of research involving human subjects. Five decades later, in this issue of Perspectives in Biology and Medicine, we pay tribute to the lasting significance of this whistle-blowing article and to the remarkable contributions of (...) Beecher. Beecher was a pioneer in anesthesiology as an academic discipline and in research on pain and the placebo effect. He was an early and influential champion of randomized placebo-controlled... (shrink)
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  27. La bioética: el punto de vista del outsider.Warren Reich - 2008 - Medicina y Ética 19:197-218.
    A cuarenta años del inicio del fecundo diálogo entre las ciencias de la vida y los estudios humanísticos, que el nacimiento de la bioética ha hecho posible, se advierte la necesidad de evaluar algunos a,spectos -entre los cuales las posibilidades futuras de la bioética, y también su origen- desde un punto de vista particular: el del outsider. Se trata de aceptar el reto, para nuestra identidad moral, de trasladar la atención del estudio de casos particulares, del punto de vista del (...)
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  28.  19
    “Ethics and Clinical Research” in Biographical Perspective.Susan E. Lederer - 2016 - Perspectives in Biology and Medicine 59 (1):18-36.
    Fifty years ago, Henry Knowles Beecher published his essay on clinical research ethics in the New England Journal of Medicine. The culmination of more than a decade and a half’s rumination and reflection on the use of patients and “captive populations” in research, Beecher’s 1966 article understandably casts a large shadow in American bioethics. In 1976, the Institute of Society, Ethics and the Life Sciences established the Henry Knowles Beecher Award for Contributions to Ethics and (...)
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  29.  54
    Ethics in Medicine: Historical Perspectives and Contemporary Concerns.Stanley Joel Reiser, Mary B. Saltonstall Professor of Population Ethics Arthur J. Dyck, Arthur J. Dyck & William J. Curran - 1977 - Cambridge: Mass. : MIT Press.
    This book is a comprehensive and unique text and reference in medical ethics. By far the most inclusive set of primary documents and articles in the field ever published, it contains over 100 selections. Virtually all pieces appear in their entirety, and a significant number would be difficult to obtain elsewhere. The volume draws upon the literature of history, medicine, philosophical and religious ethics, economics, and sociology. A wide range of topics and issues are covered, such as law and medicine, (...)
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  30.  12
    Derek Attridge: The Singularity of Literature.Derek Attridge - 2004 - New York: Routledge.
    The Iliad and Beowulf provide rich sources of historical information. The novels of Henry Fielding and Henry James may be instructive in the art of moral living. Some go further and argue that Emile Zola and Harriet Beecher Stowe played a part in ameliorating the lives of those existing in harsh circumstances. However, as Derek Attridge argues in this outstanding and acclaimed book, none of these capacities is distinctive of literature. What is the singularity of literature? Do (...)
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  31.  43
    Practical Reasoning About Final Ends.Henry S. Richardson - 1994 - Cambridge, England: Cambridge University Press.
    Henry Richardson argues that we can determine our ends rationally. He constructs a rich and original theory of how we can reason about our final goals. Richardson defuses the counter-arguments for the limits of rational deliberation, and develops interesting ideas about how his model might be extended to interpersonal deliberation of ends, taking him to the borders of political theory. Along the way Richardson offers illuminating discussions of, inter alia, Aristotle, Aquinas, Sidgwick, and Dewey, as well as the work (...)
  32. Kant's Theory of Freedom.Henry E. Allison - 1990 - New York: Cambridge University Press.
    In his new book the eminent Kant scholar Henry Allison provides an innovative and comprehensive interpretation of Kant's concept of freedom. The author analyzes the concept and discusses the role it plays in Kant's moral philosophy and psychology. He also considers in full detail the critical literature on the subject from Kant's own time to the present day. In the first part Professor Allison argues that at the centre of the Critique of Pure Reason there is the foundation for (...)
  33.  46
    Kant's Transcendental Deduction: An Analytic-Historical Commentary.Henry E. Allison - 2015 - Oxford, GB: Oxford University Press UK.
    Henry E. Allison presents an analytical and historical commentary on Kant`s transcendental deduction of the pure concepts of the understanding in the Critique of Pure Reason. He argues that, rather than providing a new solution to an old problem, it addresses a new problem, and he traces the line of thought that led Kant to the recognition of the significance of this problem in his 'pre-critical' period. In addition to the developmental nature of the account of Kant`s views presented (...)
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  34.  25
    Practical Reasoning About Final Ends.Henry S. Richardson - 1994 - Cambridge, England: Cambridge University Press.
    Henry Richardson argues that we can determine our ends rationally. He constructs a rich and original theory of how we can reason about our final goals. Richardson defuses the counter-arguments for the limits of rational deliberation, and develops interesting ideas about how his model might be extended to interpersonal deliberation of ends, taking him to the borders of political theory. Along the way Richardson offers illuminating discussions of, inter alia, Aristotle, Aquinas, Sidgwick, and Dewey, as well as the work (...)
  35. Kant’s Theory of Taste: A Reading of the Critique of Aesthetic Judgment.Henry Allison - 2001 - New York: Cambridge University Press.
    This book constitutes one of the most important contributions to recent Kant scholarship. In it, one of the pre-eminent interpreters of Kant, Henry Allison, offers a comprehensive, systematic, and philosophically astute account of all aspects of Kant's views on aesthetics. The first part of the book analyses Kant's conception of reflective judgment and its connections with both empirical knowledge and judgments of taste. The second and third parts treat two questions that Allison insists must be kept distinct: the normativity (...)
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  36.  70
    Idealism and Freedom: Essays on Kant’s Theoretical and Practical Philosophy.Henry E. Allison - 1996 - New York: Cambridge University Press.
    Henry Allison is one of the foremost interpreters of the philosophy of Kant. This new volume collects all his recent essays on Kant's theoretical and practical philosophy. All the essays postdate Allison's two major books on Kant, and together they constitute an attempt to respond to critics and to clarify, develop and apply some of the central theses of those books. Two are published here for the first time. Special features of the collection are: a detailed defence of the (...)
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  37.  30
    Logical Self-Defense.Ralph Henry Johnson & J. Anthony Blair - 1977 - Toronto, Canada: Mcgraw-Hill.
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  38. The Elements of Politics.Henry Sidgwick - 1908 - Bristol, U.K.: Cambridge University Press.
    One of the most influential of the Victorian philosophers, Henry Sidgwick also made important contributions to fields such as economics, political theory and classics. A proponent of the utilitarianism of Jeremy Bentham and John Stuart Mill, which he analysed in his classic work The Methods of Ethics, he later turned to the practical side of politics in this work, published in 1891. His aim was to have a 'rational discussion of political questions in modern states', and he offers a (...)
     
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  39.  30
    Kant’s Transcendental Idealism: An Interpretation and Defense.Henry E. Allison - 2004 - Yale University Press.
    This landmark book is now reissued in a new edition that has been vastly rewritten and updated to respond to recent Kantian literature. It includes a new discussion of the Third Analogy, a greatly expanded discussion of Kant’s _Paralogisms, _and entirely new chapters dealing with Kant’s theory of reason, his treatment of theology, and the important Appendix to the Dialectic. _Praise for the earlier edition: _ “Probably the most comprehensive and substantial study of the Critique of Pure Reason written by (...)
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  40.  60
    An Introduction to Mill’s Utilitarian Ethics.Henry R. West - 2003 - New York: Cambridge University Press.
    John Stuart Mill was the leading British philosopher of the nineteenth century and his famous essay Utilitarianism is the most influential statement of the philosophy of utilitarianism: that actions, laws, policies and institutions are to be evaluated by their utility or contribution to good or bad consequences. Henry West has written the most up-to-date and user-friendly introduction to utilitarianism available. The book serves as both a commentary to and interpretation of the text. It also defends Mill against his critics. (...)
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  41. The Methods of Ethics.Henry Sidgwick - 1907 - Revista Portuguesa de Filosofia 30 (4):401-401.
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  42. The Methods of Ethics.Henry Sidgwick - 1874 - International Journal of Ethics 4 (4):512-514.
     
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  43. The Methods of Ethics.Henry Sidgwick - 1890 - International Journal of Ethics 1 (1):120-121.
     
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  44. The Methods of Ethics.Henry Sidgwick - 1903 - International Journal of Ethics 13 (2):251-254.
     
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  45.  30
    Against Relativism.Henry Rosemont - 1989 - In Richard Rorty (ed.), Review of I nterpreting Across Boundaries: New Essays in Comparative Philosophy. University of Hawaii Press. pp. 36-70.
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  46.  20
    Darwin machines and the nature of knowledge.Henry C. Plotkin - 1994 - Cambridge: Harvard University Press.
    Bringing together evolutionary biology, psychology, and philosophy, Henry Plotkin presents a new science of knowledge, one that traces an unbreakable link between instinct and our ability to know.
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  47.  31
    Kant's Groundwork for the Metaphysics of Morals: A Commentary.Henry Allison - 2011 - New York, USA: Oxford University Press.
    Henry E. Allison presents a comprehensive commentary on Kant's Groundwork for the Metaphysics of Morals. Allison pays special attention to the structure of the work and its historical and intellectual context. He argues that, despite its relative brevity, the Groundwork is the single most important work in modern moral philosophy.
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  48.  2
    The Technique of Theory Construction.Joseph Henry Woodger - 1964 - University of Chicago Press.
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  49. Border crossings: cultural workers and the politics of education.Henry A. Giroux - 1992 - New York: Routledge.
    Since 1992, Border Crossings has show cased Henry A. Giroux's extraordinary range as a thinker by bringing together a series of essays that refigure the relationship between post-modernism, feminism, cultural studies and critical pedagogy. With discussions of topics including the struggle over academic canon, the role of popular culture in the curriculum and the cultural war the New Right has waged on schools, Giroux identified the most pressing issues facing critical educators at the turn of the century. In this (...)
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  50.  27
    Relating Protocols For Dynamic Dispute With Logics For Defeasible Argumentation.Henry Prakken - 2001 - Synthese 127 (1-2):187-219.
    This article investigates to what extent protocols for dynamicdisputes, i.e., disputes in which the information base can vary at differentstages, can be justified in terms of logics for defeasible argumentation. Firsta general framework is formulated for dialectical proof theories for suchlogics. Then this framework is adapted to serve as a framework for protocols fordynamic disputes, after which soundness and fairness properties are formulated for such protocols relative to dialectical proof theories. It then turns out that certaintypes of protocols that are (...)
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