Results for 'David Haig'

976 found
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  1. The strategic gene.David Haig - 2012 - Biology and Philosophy 27 (4):461-479.
    Abstract Gene-selectionists define fundamental terms in non-standard ways. Genes are determinants of difference. Phenotypes are defined as a gene’s effects relative to some alternative whereas the environment is defined as all parts of the world that are shared by the alternatives being compared. Environments choose among phenotypes and thereby choose among genes. By this process, successful gene sequences become stores of information about what works in the environment. The strategic gene is defined as a set of gene tokens that combines (...)
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  2. Weismann rules! OK? Epigenetics and the Lamarckian temptation.David Haig - 2007 - Biology and Philosophy 22 (3):415-428.
    August Weismann rejected the inheritance of acquired characters on the grounds that changes to the soma cannot produce the kind of changes to the germ-plasm that would result in the altered character being transmitted to subsequent generations. His intended distinction, between germ-plasm and soma, was closer to the modern distinction between genotype and phenotype than to the modern distinction between germ cells and somatic cells. Recently, systems of epigenetic inheritance have been claimed to make possible the inheritance of acquired characters. (...)
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  3.  71
    Haig’s ‘strange inversion of reasoning’ and Making sense: information interpreted as meaning.David Haig & Daniel Dennett - unknown
    David Haig propounds and illustrates the unity of a radically revised set of definitions of the family of terms at the heart of philosophy of cognitive science and mind: information, meaning, interpretation, text, choice, possibility, cause. This biological re-grounding of much-debated concepts yields a bounty of insights into the nature of meaning and life. An interpreter is a mechanism that uses information in choice. The capabilities of the interpreter couple an entropy of inputs to an entropy of outputs (...)
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  4.  34
    Genetic dissent and individual compromise.David Haig - 2014 - Biology and Philosophy 29 (2):233-239.
    Organisms can be treated as optimizers when there is consensus among their genes about what is best to be done, but genomic consensus is often lacking, especially in interactions among kin because kin share some genes but not others. Grafen adopts a majoritarian perspective in which an individual’s interests are identified with the interests of the largest coreplicon of its genome, but genomic imprinting and recombination factionalize the genome so that no faction may predominate in some interactions among kin. Once (...)
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  5.  28
    Intracellular evolution of mitochondrial DNA (mtDNA) and the tragedy of the cytoplasmic commons.David Haig - 2016 - Bioessays 38 (6):549-555.
    Mitochondria exist in large numbers per cell. Therefore, the strength of natural selection on individual mtDNAs for their contribution to cellular fitness is weak whereas the strength of selection in favor of mtDNAs that increase their own replication without regard for cellular functions is strong. This problem has been solved for most mitochondrial genes by their transfer to the nucleus but a few critical genes remain encoded by mtDNA. Organisms manage the evolution of mtDNA to prevent mutational decay of essential (...)
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  6.  12
    Transposable elements: Self‐seekers of the germline, team‐players of the soma.David Haig - 2016 - Bioessays 38 (11):1158-1166.
    The germ track is the cellular path by which genes are transmitted to future generations whereas somatic cells die with their body and do not leave direct descendants. Transposable elements (TEs) evolve to be silent in somatic cells but active in the germ track. Thus, the performance of most bodily functions by a sequestered soma reduces organismal costs of TEs. Flexible forms of gene regulation are permissible in the soma because of the self‐imposed silence of TEs, but strict licensing of (...)
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  7.  36
    Sameness, novelty, and nominal kinds.David Haig - 2015 - Biology and Philosophy 30 (6):857-872.
    Organisms and their genomes are mosaics of features of different evolutionary age. Older features are maintained by ‘negative’ selection and comprise part of the selective environment that has shaped the evolution of newer features by ‘positive’ selection. Body plans and body parts are among the most conservative elements of the environment in which genetic differences are selected. By this process, well-trodden paths of development constrain and direct paths of evolutionary change. Structuralism and adaptationism are both vindicated. Form plays a selective (...)
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  8.  53
    Fighting the good cause: meaning, purpose, difference, and choice.David Haig - 2014 - Biology and Philosophy 29 (5):675-697.
    Concepts of cause, choice, and information are closely related. A cause is a choice that can be held responsible. It is a difference that makes a difference. Information about past causes and their effects is a valuable commodity because it can be used to guide future choices. Information about criteria of choice is generated by choosing a subset from an ensemble for ‘reasons’ and has meaning for an interpreter when it is used to achieve an end. Natural selection evolves interpreters (...)
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  9.  7
    A Textual Deconstruction of the RNA World.David Haig - forthcoming - Biosemiotics:1-6.
    RNAs can do many things. They can store information, act in the world, and respond to the world. Because of these capabilities biologists have proposed a primordial ‘RNA world’ in which RNA, rather than DNA, performed the central role of replicator and repository of adaptive information. Deacon dismisses this hypothesis because replication is not about anything and because the structure of replicating molecules cannot contain information about the environment. I dispute both claims. An RNA and its opposite-sense complement represent each (...)
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  10.  15
    Genomic vagabonds: Endogenous retroviruses and placental evolution (comment on DOI 10.1002/bies.201300059).David Haig - 2013 - Bioessays 35 (10):845-846.
  11.  6
    Concerted evolution of ribosomal DNA: Somatic peace amid germinal strife.David Haig - 2021 - Bioessays 43 (12):2100179.
    Most eukaryotes possess many copies of rDNA. Organismal selection alone cannot maintain rRNA function because the effects of mutations in one rDNA are diluted by the presence of many other rDNAs. rRNA quality is maintained by processes that increase homogeneity of rRNA within, and heterogeneity among, germ cells thereby increasing the effectiveness of cellular selection on ribosomal function. A successful rDNA repeat will possess adaptations for spreading within tandem arrays by intranuclear selection. These adaptations reside in the non‐coding regions of (...)
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  12.  16
    Do imprinted genes have few and small introns?David Haig - 1996 - Bioessays 18 (5):351-353.
    A gene is described as imprinted if its pattern of expression depends on whether it passed the previous generation in a male or female germ line. A recent paper(1) reports that imprinted genes have fewer and smaller introns than a control set of genes. The differences are striking but their interpretation is unclear. The loss of introns after a gene becomes imprinted is not sufficient to explain why imprinted genes have fewer introns than average, because related unimprinted genes also have (...)
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  13.  23
    Kinship asymmetries and the divided self.David Haig - 2008 - Behavioral and Brain Sciences 31 (3):271-272.
    Imprinted genes are predicted to affect interactions among relatives. Therefore, variant alleles at imprinted loci are promising candidates for playing a causal role in disorders of social behavior. The effects of imprinted genes evolved in the context of patterns of asymmetric relatedness that existed within social groups of our ancestors.
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  14.  49
    Lamarck Ascending!David Haig - 2011 - Philosophy, Theory, and Practice in Biology 3 (20130604).
    Transformations of Lamarckism is an edited volume arising from a workshop to commemorate the bicentenary of the publication of Philosophie Zoologique. The contributed chapters discuss the history of Lamarckism, present new developments in biology that could be considered to vindicate Lamarck, and argue for a revision, if not a revolution, in evolutionary theory. My review argues that twentieth and twenty-first century conceptions of Lamarckism can be considered a reaction to August Weismann’s uncompromising rejection of the inheritance of acquired characters in (...)
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  15.  10
    Paradox lost: Concerted evolution and centromeric instability.David Haig - 2022 - Bioessays 44 (8):2200023.
    Homologous centromeres compete for segregation to the secondary oocyte nucleus at female meiosis I. Centromeric repeats also compete with each other to populate centromeres in mitotic cells of the germline and have become adapted to use the recombinational machinery present at centromeres to promote their own propagation. Repeats are not needed at centromeres, rather centromeres appear to be hospitable habitats for the colonization and proliferation of repeats. This is probably an indirect consequence of two distinctive features of centromeric DNA. Centromeres (...)
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  16.  70
    Sleeping Beauty in a grain of rice.David Haig - 2016 - Biology and Philosophy 31 (1):23-37.
    In the Sleeping Beauty problem, Beauty is woken once if a coin lands heads or twice if the coin lands tails but promptly forgets each waking on returning to sleep. Philosophers have divided over whether her waking credence in heads should be a half or a third. Beauty has centered beliefs about her world and about her location in that world. When given new information about her location she should update her worldly beliefs before updating her locative beliefs. When she (...)
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  17.  76
    Proximate and ultimate causes: how come? and what for? [REVIEW]David Haig - 2013 - Biology and Philosophy 28 (5):781-786.
    Proximate and ultimate causes in evolutionary biology have come to conflate two distinctions. The first is a distinction between immediate and historical causes. The second is between explanations of mechanism and adaptive function. Mayr emphasized the first distinction but many evolutionary biologists use proximate and ultimate causes to refer to the second. I recommend that ‘ultimate cause’ be abandoned as ambiguous.
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  18.  2
    Quality and Pleasure in Latin Poetry.Julia Haig Gaisser, Tony Woodman & David West - 1976 - American Journal of Philology 97 (4):414.
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  19.  21
    Going retro: Transposable elements, embryonic stem cells, and the mammalian placenta (retrospective on DOI 10.1002/bies.201300059). [REVIEW]David Haig - 2015 - Bioessays 37 (11):1154-1154.
  20. Does intragenomic conflict predict intrapersonal conflict?David Spurrett - 2016 - Biology and Philosophy 31 (3):313-333.
    Parts of the genome of a single individual can have conflicting interests, depending on which parent they were inherited from. One mechanism by which these conflicts are expressed in some taxa, including mammals, is genomic imprinting, which modulates the level of expression of some genes depending on their parent of origin. Imprinted gene expression is known to affect body size, brain size, and the relative development of various tissues in mammals. A high fraction of imprinted gene expression occurs in the (...)
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  21.  48
    R.G. Dennis, M.C.J. Putnam The Complete Poems of Tibullus. An en face bilingual edition. With an introduction by Julia Haig Gaisser. Pp. x + 159. Berkeley, Los Angeles and London: University of California Press, 2012. Paper, £13.95, US$19.95 . ISBN: 978-0-520-27254-5 .A.M. Juster Tibullus: Elegies, with Parallel Latin Text. With an introduction and notes by Robert Maltby. Pp. xxxiv + 129. Oxford: Oxford University Press, 2012. Paper, £8.99, US$14.95. ISBN: 978-0-19-960331-2. [REVIEW]David Wray - 2013 - The Classical Review 63 (2):427-432.
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  22.  7
    David Haig, "From Darwin to Derrida: Selfish Genes, Social Selves, and the Meanings of Life.".Evan Clarke - 2021 - Philosophy in Review 41 (3):188-190.
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  23.  14
    David Haig: From Darwin to Derrida: Selfish Genes, Social Selves, and the Meanings of Life.Bernard Wood - 2021 - Evolutionary Studies in Imaginative Culture 5 (1):85-86.
  24.  12
    From Darwin to Derrida: Selfish Genes, Social Selves, and the Meanings of Life,: by David Haig, Cambridge, MA, MIT Press, 2020, 464 pp., $39.95T/£32.00.Stanley Shostak - 2021 - The European Legacy 27 (5):523-526.
    David Haig’s From Darwin to Derrida scrutinizes a wide range of historical and contemporary issues embedded in the theory and practice of genetics—from genes to multilevel selection, from prokaryot...
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  25.  44
    Review of From Darwin to Derrida by David Haig[REVIEW]Samir Okasha - 2020 - Acta Biotheoretica 69 (3):477-481.
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  26.  8
    Review of From Darwin to Derrida by David Haig: MIT Press 2020. ISBN 9780262043786. [REVIEW]Samir Okasha - 2020 - Acta Biotheoretica 69 (3):477-481.
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  27.  53
    Homology and the evolutionary process: reply to Haig, Love and Brown on “Homology, Genes and Evolutionary Innovation”.Günter P. Wagner - 2015 - Biology and Philosophy 30 (6):901-912.
    This paper responds to the essay reviews by David Haig, Alan Love and Rachel Brown of my recently published book “Homology, Genes and Evolutionary Innovation”. The issues addressed here relate to: the notion of classes and individuals, issues of explanatory value of adaptive and structuralist explanations in evolutionary biology, the role of homology in evolutionary theory, the limits of a pluralist stance vis a vis alternative explanations of homology, as well as the question whether and to what extend (...)
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  28.  24
    Art and the Aesthetic, An Institutional Analysis.Haig Khatchadourian - 1979 - Noûs 13 (1):113-117.
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  29.  13
    The Literary Work of Art: An Investigation on the Borderlines of Ontology, Logic, and Theory of Literature.Haig Khatchadourian - 1974 - Journal of Aesthetics and Art Criticism 33 (2):217-220.
  30. Consciousness is Underived Intentionality.David Bourget - 2010 - Noûs 44 (1):32 - 58.
    Representationalists argue that phenomenal states are intentional states of a special kind. This paper offers an account of the kind of intentional state phenomenal states are: I argue that they are underived intentional states. This account of phenomenal states is equivalent to two theses: first, all possible phenomenal states are underived intentional states; second, all possible underived intentional states are phenomenal states. I clarify these claims and argue for each of them. I also address objections which touch on a range (...)
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  31.  8
    Imperatives and their Logics.Haig Khatchadourian - 1978 - Philosophy and Phenomenological Research 39 (2):283-284.
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  32.  46
    What Mystical Experiences Tell Us About Human Knowledge.David Cycleback - 2021 - In Brain Function and Religion. Seattle (USA): Center for Artifact Studies. pp. 5-15.
    From religion to philosophy to science, all human systems of definition are formed by human brains. The nature and limits of the human brain are the nature and limits of those systems. This essay shows how the human brain works normally then unusually, and what this reveals about the limits of human knowledge. There are many conditions and instances where the brain processes information unusually, including mental disorders, physical events, and drug use. This essay focuses on the neurological events called (...)
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  33.  11
    A New Theory of Beauty.Haig Khatchadourian - 1975 - Journal of Aesthetics and Art Criticism 35 (3):361-363.
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  34.  6
    A Medical View.Haig H. Kazazian - 1980 - Hastings Center Report 10 (1):17-18.
  35. Science in revolt.Haig M. Mosditchian - 1968 - Nicosia, Cyprus: Nicosia, Cyprus.
  36.  69
    The Psychology of Decision Making.David Cycleback - forthcoming - London (UK): Bookboon.
    This short peer-reviewed text is a concise look at the psychology of how human beings make decisions, including how they form their worldviews and make arguments.
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  37. Physical Necessitism.David Elohim - unknown
    This paper aims to provide two abductive considerations adducing in favor of the thesis of Necessitism in modal ontology. I demonstrate how instances of the Barcan formula can be witnessed, when the modal operators are interpreted 'naturally' -- i.e., as including geometric possibilities -- and the quantifiers in the formula range over a domain of natural, or concrete, entities and their contingently non-concrete analogues. I argue that, because there are considerations within physics and metaphysical inquiry which corroborate modal relationalist claims (...)
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  38. Do Dead Bodies Pose a Problem for Biological Approaches to Personal Identity?David Hershenov - 2005 - Mind 114 (453):31 - 59.
    Part of the appeal of the biological approach to personal identity is that it does not have to countenance spatially coincident entities. But if the termination thesis is correct and the organism ceases to exist at death, then it appears that the corpse is a dead body that earlier was a living body and distinct from but spatially coincident with the organism. If the organism is identified with the body, then the unwelcome spatial coincidence could perhaps be avoided. It is (...)
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  39.  17
    John Locke’s “Unease”: The Theoretical Foundation of the Modern Separation of Church and State.Haig Patapan & Jeffrey Sikkenga - forthcoming - Political Theory.
    John Locke is acknowledged to be one of the theoretical founders of the separation of church and state, a distinguishing feature of modern liberal democracies. Though Locke’s arguments for the merits of such separation have been subject to extensive investigation, his argument for its feasibility has remained relatively unexamined. This article argues that Locke was confident that separation of church and state can successfully be implemented in all times and places because of his epistemological and psychological insights that human beings (...)
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  40.  5
    Judging Democracy: The New Politics of the High Court of Australia.Haig Patapan - 2000 - Cambridge University Press.
    The High Court is taking an increasingly important role in shaping the contours of democracy in Australia. In deciding fundamental democratic questions, does the Court pursue a consistent and overarching democratic vision? Or are its decisions essentially constrained by institutional and practical limitations? Judging Democracy, first published in 2000, addresses this question by examining the Court's recent decisions on human rights, citizenship, native title and separation of powers. It represents the first major political and legal examination of the Court's new (...)
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  41.  55
    Enquiry Concerning Human Understanding.David Hume (ed.) - 1904 - Clarendon Press.
    Oxford Philosophical Texts Series Editor: John Cottingham The Oxford Philosophical Texts series consists of authoritative teaching editions of canonical texts in the history of philosophy from the ancient world down to modern times. Each volume provides a clear, well laid out text together with a comprehensive introduction by a leading specialist, giving the student detailed critical guidance on the intellectual context of the work and the structure and philosophical importance of the main arguments. Endnotes are supplied which provide further commentary (...)
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  42. Parts of Classes.David K. Lewis - 1990 - Blackwell.
  43.  30
    The politics of modern honor.Haig Patapan - 2018 - Contemporary Political Theory 17 (4):459-477.
    Modern honor appears to be distinguished by two contradictory impulses, a neglect or even disdain of honor, and an ambition to elevate and promote it as dignity, self-esteem, and recognition. The article argues that these tensions can be traced to a foundational difference regarding the political importance of the passion of honor, evident in the seminal and contending formulations by Machiavelli and Hobbes. In recovering and articulating the bases of these competing modern conceptions of honor and tracing the influence of (...)
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  44.  16
    Armenia. Art, Religion, and Trade in the Middle Ages, edited by Helen C. Evans, New York: The Metropolitan Museum of Art 2018 Christina Maranci, The Art of Armenia. An Introduction, New York: Oxford University Press 2018. [REVIEW]Haig Utidjian - 2019 - Convivium 6 (2):147-150.
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  45.  8
    More on Galois Cohomology, Definability, and Differential Algebraic Groups.Omar León Sánchez, David Meretzky & Anand Pillay - forthcoming - Journal of Symbolic Logic:1-20.
    As a continuation of the work of the third author in [5], we make further observations on the features of Galois cohomology in the general model theoretic context. We make explicit the connection between forms of definable groups and first cohomology sets with coefficients in a suitable automorphism group. We then use a method of twisting cohomology (inspired by Serre’s algebraic twisting) to describe arbitrary fibres in cohomology sequences—yielding a useful “finiteness” result on cohomology sets. Applied to the special case (...)
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  46.  20
    The Philosophical Works of David Hume.David Hume - 2015 - Palala Press.
    This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...)
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  47.  11
    Jun-Hyeok Kwak ed. Machiavelli in Northeast Asia.Haig Patapan - 2023 - Journal of Social and Political Philosophy 2 (2):231-233.
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  48.  22
    "Lord over the children of pride": The.Haig Patapan - 2000 - Philosophy and Rhetoric 33 (1):1.
    In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 33.1 (2000) 74-93 [Access article in PDF] "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's Leviathan Haig Patapan Hobbes claimed in the Leviathan that he had, by "industrious meditation," discovered the Principles of Reason that would allow Commonwealths to be everlasting. He claimed, in other words, to have solved the political problem (1968, chap. 30, 378). All that was now required was (...)
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  49.  13
    "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's Leviathan.Haig Patapan - 2000 - Philosophy and Rhetoric 33 (1):74-93.
    In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 33.1 (2000) 74-93 [Access article in PDF] "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's Leviathan Haig Patapan Hobbes claimed in the Leviathan that he had, by "industrious meditation," discovered the Principles of Reason that would allow Commonwealths to be everlasting. He claimed, in other words, to have solved the political problem (1968, chap. 30, 378). All that was now required was (...)
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  50.  13
    The Foundations of Aesthetics.Haig Khatchadourian - 1979 - Journal of Aesthetics and Art Criticism 38 (2):193-195.
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