This volume provides a fresh perspective on current democratic theory and practice by recovering the rich evaluations of democracy in the history of political thought. Each essay addresses a single thinker’s reflections on the virtues and defects of democracy and the relationship between democracy and other regimes.

We study active set methods for optimization problems in Block Angular Form (BAF). We begin by reviewing some standard basis factorizations, including Saunders' orthogonal factorization and updates for the simplex method that do not impose any restriction on the pivot sequence and maintain the basis factorization structured in BAF throughout the algorithm. We then suggest orthogonal factorization and updating procedures that allow coarse grain parallelization, pivot updates local to the affected blocks, and independent block reinversion. A simple parallel (...) environment appropriate to the description and complexity analysis of test procedures is defined in Section 5. The factorization and updating procedures are presented in Sections 6 and 7. Our update procedure outperforms conventional Updating procedures even in a purely sequential environment. (shrink)

This volume is a collection of new and previously published essays focusing on one of the most exciting and actively discussed topics in contemporary philosophy: naturalistic theories of mental content. The volume brings together important papers written by some of the most distinguished theorists working in the field today. Authors contributing to the volume include Jerry Fodor, Ruth Millikan, Fred Dretske, Ned Block, Robert Cummins, and Daniel Dennett.

We describe here recent work on the molecular genetics of mitosis in the filamentous fungus Aspergillus nidulans. Aspergillus is one of three simple eukaryotes with powerful genetic systems that have been used to analyze mitosis. The modern molecular biological techniques available with this organism have made it possible to use mutations to identify genes and proteins that play an important role in mitosis. Three Aspergillus genes that affect mitosis are described. One gene, nimA, is specifically expressed late in the cell (...) cycle and codes for a putative protein kinase that induces mitosis, even in cells blocked in S‐phase. The second gene, bimG, codes for a putative phosphatase that interacts functionally with the nimA kinase. The third gene, bimE, codes for a protein that suppresses mitosis during interphase, apparently by keeping nimA turned off. None of these genes appear to be similar to any of the genes affecting mitosis that have been characterized in other eukaryotes, but rather appear to be elements of a system that prevents mitosis from occurring during interphase. (shrink)

Ribonucleotide reductase (RNR) catalyzes the rate limiting step in the production of deoxyribonucleotides needed for DNA synthesis. In addition to the well documented allosteric regulation, the synthesis of the enzyme is also tightly regulated at the level of transcription. mRNAs for both subunits are cell cycle regulated and inducible by DNA damage in all organisms examined, including E. coli, S. cerevisiae and H. sapiens. This DNA damage regulation is thought to provide a metabolic state that facilitates DNA replicational repair processes. (...) S. cerevisiae also encodes a second large subunit gene, RNR3, that is expressed only in the presence of DNA damage. Genetic analysis of the DNA damage response in S. cerevisiae has shown that RNR expression is under both positive and negative control. Among mutants constitutive for RNR expression are the general transcriptional repression genes, SSN6 and TUP1. Mutations in POL1 and POL3 also activate RNR expression, indicating that the DNA damage sensory network may respond directly to blocks in DNA synthesis. A protein kinase, Dun1, has been identified that controls inducibility of RNR1, RNR2 and RNR3 in response to DNA damage and replication blocks. This result suggests that the RNR genes in S. cerevisiae form a regulon that is coordinately regulated by protein phosphorylation in response to DNA damage. (shrink)

The "great debate" in cognitive science today is about the nature of mental images. One side says images are basically pictures in the head. The other side says they are like the symbol structures in computers. If the picture-in-the-head theorists are right, then computers will never be able to think like people.This book contains the most intelligible and incisive articles in the debate, articles by cognitive psychologists, computer scientists and philosophers. The most exciting imagery phenomena are described, phenomena that indicate (...) that mental images can be rotated and scanned, that smaller images are harder to see than larger ones, that when mental images are made larger they eventually overflow, that the "screen" they overflow from has a determinable shape (elliptical), and that this "screen" subtends a determinate visual angle, the angle of vision of the mind's eye.Such experiments cry out for explanation. If images are pictures in the head, who (or what) looks at them? Why haven't brain scientists found them? Such questions are the subject of the great debate.IMAGERY is an excellent choice for courses in cognitive psychology, perception: artificial intelligence, computer science; philosophy of mind, of psychology and of science; minds and machines, science and society.Contributors include: Roger Brown and Richard Herrnstein (on the work of Roger N. Shepard), Daniel Dennett, Jerry Fodor, Robert Schwartz, Stephen Kosslyn, Steven Pinker, George Smith, Steven Shwartz, and Zenon Pylyshyn,. (shrink)

Skeptical theism is a leading response to the evidential argument from evil against the existence of God. Skeptical theists attempt to block the inference from the existence of inscrutable evils to gratuitous evils by insisting that given our cognitive limitations, it wouldn’t be surprising if there were God-justifying reasons we can’t think of. A well-known objection to skeptical theism is that it opens up a skeptical Pandora’s box, generating implausibly wide-ranging forms of skepticism, including skepticism about the external world (...) and past. This paper looks at several responses to this Pandora’s box objection, including a popular response devised by Beaudoin and Bergmann. I find that all of the examined responses fail. It appears the Pandora’s box objection to skeptical theism still stands. (shrink)

The notion of a mental interior has been derided as a Cartesian relic, the 'ghost in the machine' (Ryle, 1963). Yet there is a mental interior — indeed, there are two — only not where we tend to look. When a toddler talks to herself before sleep, she often plays the part of a parent toward herself, mitigating the dread of separation. She thus creates a pretend space between herself-as-parent and herself-as-child. Growing up, she plays others toward herself as well. (...) She and her simulated interlocutors are experienced by her as an expanded self with an inside, namely the place of inner speech. This pretend space is the first non-bodily interior. The second develops as a consequence. The simulated others diminish the dependence on actual others, who therefore cease to appear in their former importance. One yearns for them as they were, but the yearning is blocked — and banished from awareness — by dread of reverting to the earlier dependence. This second interior is the space between the unconscious self and the full kind of other for whom it yearns. The yearning enters conscious life indirectly and unthreateningly, for example in the fictive frame of art and in the relational frame of conversation. (shrink)

For the past few years I've had the distinct privilege to edit the Hastings Center Report's Policy & Politics column. The column—as indicated by a little block of text at its end—was originally conceived as, and remains, a joint production of HCR and the American Society for Bioethics and Humanities. For me, as column editor, this means that I can accept contributions only from ASBH members. Luckily this presents me with an extremely large pool of talent from which to (...) draw! I am very proud of the fact that a large majority of contributors to the column in the last several years had never written in HCR before I invited them to contribute. But naturally, I don't know everyone, and I can't keep track of everything. I'd love to get even more unsolicited offers of P&P contributions than I already enjoy. (shrink)

In this paper, I argue for the Complex Experiential Theory. It asserts that pleasure is a pro-attitude toward a de se experience. I argue that it is better than its competitors. In particular, it is better than monadic theories that view pleasure as a distinct type of experience or a pro-attitude in isolation. It is also better than other non-monadic theories. In particular, it is better than accounts that involve pro-attitudes and beliefs in states of affairs or propositions (or ones (...) that obtain, are true, or that focus on the subject’s own life). When conjoined with hedonism, this theory fits nicely into a building block theory of well-being. (shrink)

There is widespread agreement that ethical concerns are central to decision-making about, and governance of, geoengineering. This is especially true of the most prominent and paradigm example of climate engineering, the spraying of sulfate particles into the stratosphere in order to block incoming sunlight and so limit global warming ). Geoengineering ethics, like geoengineering science, is still in its early, exploratory days. This chapter offers an introductory overview of the emerging discussion and some of the challenges moving forward, taking (...) SSI as its key example. It identifies a range of values relevant to geoengineering, exposes some misleading early framings, argues that questions of justification and context are both important, and summarizes the Tollgate principles for geoengineering governance. One theme is that despite the initial agreement on the centrality of ethics, in practice there are profound risks that ethical considerations will be marginalized, both in the short-term as research is developed, and in the longer-run, in any deployment. (shrink)

Newcomb's problem supposedly involves your choosing one or else two boxes in circumstances in which a predictor has made a prediction of how many boxes you will choose. We argue that the circumstances which allegedly define Newcomb's problem generate a previously unnoticed regress which shows that Newcomb's problem is insoluble because it is ill-formed. Those who favor, as we do, a ``no-box'' reply to Newcomb's problem typically claim either that the problem's solution is underdetermined or else that it is overdetermined. (...) We are no-boxers of the first kind, but the underdetermination we identify is more radical than any previously identified: it blocks the very set-up of the problem and not just potential solutions to the problem once it has been set up. The defect is subtle, but it cripples every genuine version of the problem, regardless of variations in such things as the predictor's degree of reliability, the basis on which the prediction is made, or the amount of money in each box. The regress shows that, surprisingly enough, no one can understand Newcomb's problem, and so no one can possibly solve it. (shrink)

Music is at the centre of what it means to be human – it is the sounds of human bodies and minds moving in creative, story-making ways. We argue that music comes from the way in which knowing bodies (Merleau-Ponty) prospectively explore the environment using habitual 'patterns of action' which we have identified as our innate ‘communicative musicality’. To support our argument, we present short case studies of infant interactions using micro analyses of video and audio recordings to show the (...) timings and shapes of intersubjective vocalisations and body movements of adult and child while they improvise shared narratives of meaning. Following a survey of the history of discoveries of infant abilities, we propose that the gestural narrative structures of voice and body seen as infants communicate with loving caregivers are the building blocks of what become particular cultural instances of the art of music, and of dance, theatre and other temporal arts. Children enter into a musical culture where their innate communicative musicality can be encouraged and strengthened through sensitive, respectful, playful, culturally informed teaching in companionship. The central importance of our abilities for music as part of what sustains our well-being is supported by evidence that communicative musicality strengthens emotions of social resilience to aid recovery from mental stress and illness. Drawing on the experience of the first author as a counsellor, we argue that the strength of one person’s communicative musicality can support the vitality of another’s through the application of skilful techniques that encourage an intimate, supportive, therapeutic, spirited companionship. Turning to brain science, we focus on hemispheric differences and the affective neuroscience of Jaak Panksepp. We emphasise that the psychobiological purpose of our innate musicality grows from the integrated rhythms of energy in the brain for prospective, sensation-seeking affective guidance of vitality of movement. We conclude with a Coda that recalls the philosophy of the Scottish Enlightenment, which built on the work of Heraclitus and Spinoza. This view places the shared experience of sensations of living – our communicative musicality – as inspiration for rules of logic formulated in symbols of language. (shrink)

The concept of evolution is widely considered to be a foundational building block in atheist thought. Leaders of the New Atheist movement have taken Darwin's work and used it to diminish the authority of religious institutions and belief systems. But they have also embraced it as a metaphor for the gradual replacement of religious faith with secular reason. They have posed as harbingers of human progress, claiming the moral high ground, and rejecting with intolerance any message that challenges the (...) hegemony of science and reason. Religion, according to the New Atheists, should be relegated to the Dark Ages of superstition and senseless violence. Yet Darwin did not see evolution as a linear progression to an improved state of being. The more antagonistic members of the New Atheist movement who embrace this idea are not only employing bad history, but also the kind of rigid, black-and-white thinking they excoriate in their religious opponents. Indeed, Stephen LeDrew argues, militant atheists have more in common with religious fundamentalists than they would care to admit, advancing what LeDrew calls secular fundamentalism. In reaction to fundamentalist Christianity and Islamism, this strain of atheism has become an offshoot of the religion it tries so hard to malign. The Evolution of Atheism outlines the essential political tension at the heart of the atheist movement. The New Atheism, LeDrew shows, is part of a tradition of atheist thought and activism that promotes individualism and scientific authority, which puts it at odds with atheist groups that are motivated by humanistic ethics and social justice. LeDrew draws on public relations campaigns, publications, podcasts, and in-depth interviews to explore the belief systems, internal logics, and self-contradictions of the people who consider themselves to be atheists. He argues that evolving understandings of what atheism means, and how it should be put into action, are threatening to irrevocably fragment the movement. (shrink)

This is a charming and engaging book that combines careful attention to the phenomenology of experience with an appreciation of the psychology and neuroscience of perception. In some of its aimsfor example, to show problems with a rigid version of a view of visual perception as an inverse optics process of constructing a static 3-D representation from static 2-D information on the retina--it succeeds admirably. As No points out, vision is a process that depends on interactions between the perceiver and (...) the environment and involves contributions from sensory systems other than the eye. He is at pains to note that vision is not passive. His analogy with touch is to the point: touch involves skillful probing and movement, and so does vision, although less obviously and in my view less centrally so. This much is certainly widely accepted among vision scientistsalthough mainstream vision scientists (represented, for example, by Stephen Palmers excellent textbook²) view these points as best seen within a version of the inverse optics view that takes inputs as non-static and as including motor instructions (for example, involving eye movements and head movements).³ The kind of point that No raises is viewed as important at the margins, but as not disturbing the main lines of the picture of vision that descendswith many changesfrom the pioneering work of David Marr in the 1980s (and before him, from Helmholtz). But No shows little interest in mainstream vision science, focusing on non-mainstream ideas in the science of perception, specifically ideas from the anti-representational psychologist J.J. Gibson, and also drawing on Wittgenstein and the phenomenology tradition. There is a sense throughout the book of revolution, of upsetting the applecart. This is a review from the point of view of the applecart. (shrink)

2. Ginet envisages a person’s fully understanding ‘what the sentence p says’ – which is the person’s fully understanding ‘what is said by one who utters p in normal circumstances in order to assert that p’ (p. 3). The understanding involved is direcError: Illegal entry in bfchar block in ToUnicode CMapted at meaning. It is one’s ‘understanding the parts and the structure of the sentence’ (ibid.). In the next section, I say more about the details of such understanding. First, (...) though, here is how it can help to constitute p’s being self-evident simpliciter (p. 13). (shrink)

There is a well-known line of thought, associated with Donald Davidson, that connects the notion of a perceptual given—of non-linguistic or non-conceptual experience of the world—with skepticism. Against this, I argue that the notion of what is given in perception leads to skepticism only on certain interpretations. I argue, in fact, that there must be perceptual experience such that there is “something it is like” to have it, or that would provide the subject of a phenomenological analysis, if we are (...) to block skepticism in its most radical forms. In particular, I claim that there is a distinctive phenomenology of the experience of agency. These phenomenological claims are conclusions of a transcendental argument according to which our having such experience is a condition of our having a meaningful language. Moreover, the same transcendental argument is sufficient to show the incoherence of radical skepticism about the external world. And I argue that the proper understanding of perceptual experience—as object involving—renders the standard objections to transcendental arguments ineffective. (shrink)

Arendt, Rawls, Walzer, de Beauvoir, Nozick, Marcuse. These names are among the absolutely essential building blocks of a political education. Stephen Bronner's Twentieth Century Political Thought: A Reader brings together dozens of the most important pieces by the thinkers who form and expand the canon of contemporary political thought. Designed as a sampler and a guide, the volume introduces the reader to contemporary debates over liberalism, socialism, fascism, postmodernism, feminism, postcolonialism and a host of other important ideas.

Few commentators (if any) would question Schrader's poignant obser­vation that 'the doctrine of the thing in itself presents the single greatest stumbling block in the Kantian philosophy' [S5:49]. Understanding what Kant meant by the doctrine i.e., the role it plays both in his overall System and in his transcendental idealism can help prevent it from being discarded 'as a per­versity' [49], inasmuch as it can be interpreted in such a way that it makes quite good sense [see VI.2]. Yet (...) even the most coherent interpretation could not prevent the philosopher who demands knowledge from 'stumbling' over it; for, accord­ing to Kant, the thing in itself is by definition unknow­able. In V.3 we saw, however, that there is one alternative to faith as the ultimate jus­tification for its employment which, if successful, would satisfy even the most persistent skeptic: viz., to justify the thing in itself by constructing a valid transcendental argument for the necessity of its existence. Since any ap­peal to faith would thereby be rendered superflu­ous, we must now examine more carefully the possibility of realizing this goal. For, although Kant him­self did not believe he required such a transcendental argu­ment, it may be pos­sible to reconstruct his System on the basis of a slightly different presup­posi­tion, such as that the thing in itself can, in fact, be proved to exist and to have certain knowable characteristics. Hence, in this Appendix I shall analyze the logical consistency of an affirmative answer to the meta­critical question: Is the thing in itself knowable? Our answer to this question will inevitably determine to a large extent how we should approach the task of interpreting the elements of Kant's Critical philosophy (as in Part Three), so it is important to deal with it seriously. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Witness of the Body: The Past, Present, and Future of Christian Martyrdom ed. by Michael L. Budde and Karen ScottElizabeth Sweeny BlockWitness of the Body: The Past, Present, and Future of Christian Martyrdom Edited by Michael L. Budde and Karen Scott Grand Rapids, Mich.: Eerdmans, 2011. 238 pp. $22.00In Michael L. Budde’s introduction to this volume, he asserts its twofold purpose: to identify criteria for distinguishing authentic Christian (...) martyrdom from inauthentic and to return martyrdom to a more central place in Christian life. This collection of essays—some of which were presented as part of a lecture series at DePaul University during the 2006–7 academic year—aspires to reconsider and redefine martyrdom in order to remove both the “freak-show element” and the “heroic exceptionality” associated with martyrdom in modern culture (viii). The goal of the volume, which is part of the Eerdmans Ekklesia Series, is to resituate martyrdom within the everyday life of the church, and the majority of the essays argue for the ongoing significance of a revised martyrdom for this distinctive community. These eleven essays are as much about martyrs themselves as they are about how martyrdom is perceived, received, and remembered. The interdisciplinary volume [End Page 211] is successful in encouraging a broader understanding of martyrdom, one that may not necessarily include death, and in drawing attention to the ongoing need for memorializing Christian martyrs to inspire commitment and transformation.The volume is divided into four parts representing both chronological and substantive distinctions. Part 1, “Martyrdom as the Church’s Witness,” introduces the problem of isolating the requirements of martyrdom and defining who fits into this category, a challenge addressed throughout the volume. Part 2, “Martyrdom Builds the Church,” discusses positive elements of martyrdom, especially with respect to the value of women’s bodies, drawing on both the early female martyrs in general and Joan of Arc in particular. Part 3, “Martyrdom Destroys the Church,” recounts some of the most difficult aspects of modern martyrdom, calling for a more accurate history and recognition of the emergence of a new kind of martyrdom in which one’s loyalty is to country, not faith. Part 4, “Martyrdom and the Future Church,” calls attention to the need to continue celebrating the memory of martyrs and describes the contemporary Christian martyr as a peacemaker not seeking martyrdom in the traditional sense of the word.What stands out as a theme across a number of the essays, and what I judge to be a valuable contribution to Christian ethics, is an emphasis on the way martyrs live(d), suggesting that what can and should be emulated by Christians today is a commitment to action on behalf of conversion and transformation. Tripp York’s essay rightly argues that martyrdom need not be viewed as merely reactionary, as a way of life in opposition to something, but as transformative and “for the sake of the world” (37). Michael Budde makes a similar assertion that martyrdom is better defined as deep loyalty than as treason, thereby suggesting that this kind of loyalty to Christ ought not to be limited to the special calling of a few but seen as the commitment of all Christians. Stephen Fowl’s essay conveys the meaning of the title of this volume, identifying martyrdom as part of the larger practice of “believers’ witness of the body to God’s drama of salvation” (44). He argues that in life or death, one can magnify Christ, and one’s bodily actions and responses can reflect one’s character and commitments. Emmanuel Katongole provides powerful recognition of the ways in which Christian martyrs “keep the church from sleeping” (193) and “embody the mundane gestures and practice of peaceableness in their everyday living” (199). This volume succeeds in shifting the focus from martyrdom in the traditional sense—being put to death because of one’s faith—to the ways Christians today remember, respond to, and emulate the lives and actions of martyrs. [End Page 212]Elizabeth Sweeny BlockUniversity of ChicagoCopyright © 2013 Society of Christian Ethics... (shrink)

In the face of limited time and escalating impacts, some scientists and politicians are talking about attempting "grand technological interventions" into the Earth’s basic physical and biological systems ("geoengineering") to combat global warming. Early ideas include spraying particles into the stratosphere to block some incoming sunlight, or "enhancing" natural biological systems to withdraw carbon dioxide from the atmosphere at a higher rate. Such technologies are highly speculative and scientific development of them has barely begun. -/- Nevertheless, it is widely (...) recognized that geoengineering raises critical questions about who will control planetary interventions, and what responsibilities they will have. Central to these questions are issues of justice and political legitimacy. For instance, while some claim that climate risks are so severe that geoengineering must be attempted, others insist that the current global order is so unjust that interventions are highly likely to be illegitimate and exacerbate injustice. Such concerns are rarely discussed in the policy arena in any depth, or with academic rigor. Hence, this book gathers contributions from leading voices and rising stars in political philosophy to respond. It is essential reading for anyone puzzled about how geoengineering might promote or thwart the ends of justice in a dramatically changing world. (shrink)

_ Source: _Page Count 25 The familiar challenges to historiographical knowledge turn on epistemological concerns having to do with the unobservability of historical events, or with the problem of establishing a sufficiently strong inferential connection between evidence and the historiographical claim one wishes to convert from a true belief into knowledge. This paper argues that these challenges miss a deeper problem, viz., the lack of obvious truth-makers for historiographical claims. The metaphysical challenge to historiography is that reality does not appear (...) to co-operate in our cognitive endeavours by providing truth-makers for claims about historical entities and events. Setting out this less familiar, but more fundamental, challenge to the very possibility of historiography is the first aim of this paper. The various ways in which this challenge might be met are then set out, including ontologically inflationary appeals to abstract objects of various kinds, or to “block” theories of time. The paper closes with the articulation of an ontologically parsimonious solution to the metaphysical challenge to historiography. The cost of this approach is a revision to standard theories of truth. The central claim here is that the standard theories of truth have mistaken distinct causes of truth for truth itself. This mistake leads to distorted expectations regarding truth-makers for historiographical claims. The truth-makers of historiographical claims are not so much the historical events themselves but atemporal modal facts about the order of things of which those events were a part. (shrink)

_ Source: _Page Count 25 The familiar challenges to historiographical knowledge turn on epistemological concerns having to do with the unobservability of historical events, or with the problem of establishing a sufficiently strong inferential connection between evidence and the historiographical claim one wishes to convert from a true belief into knowledge. This paper argues that these challenges miss a deeper problem, viz., the lack of obvious truth-makers for historiographical claims. The metaphysical challenge to historiography is that reality does not appear (...) to co-operate in our cognitive endeavours by providing truth-makers for claims about historical entities and events. Setting out this less familiar, but more fundamental, challenge to the very possibility of historiography is the first aim of this paper. The various ways in which this challenge might be met are then set out, including ontologically inflationary appeals to abstract objects of various kinds, or to “block” theories of time. The paper closes with the articulation of an ontologically parsimonious solution to the metaphysical challenge to historiography. The cost of this approach is a revision to standard theories of truth. The central claim here is that the standard theories of truth have mistaken distinct causes of truth for truth itself. This mistake leads to distorted expectations regarding truth-makers for historiographical claims. The truth-makers of historiographical claims are not so much the historical events themselves but atemporal modal facts about the order of things of which those events were a part. (shrink)

This article is a commentary on Carey (2009) The Origin of Concepts. Carey rightly rejects the building blocks model of concept acquisition on the grounds that new primitive concepts can be learned via the process of bootstrapping. But new primitives can be learned by other acquisition processes that do not involve bootstrapping, and bootstrapping itself is not a unitary process. Nonetheless, the processes associated with bootstrapping provide important insights into conceptual change.

Cognition, and mental processes, played an important role in early social theory, especially in the thought of Comte and Spencer, but a gradually reduced role in the “classics,” and a minimal role in what became the “Standard Social Science Model.” This is now changing, so this history has become quite relevant. Comte is known for his interest in phrenology, but this interest took the form of a critique of phrenology as well as of the faculty psychology of the time. This (...) critique pointed toward a modern view of cognition. Herbert Spencer, whose reputation in cognitive science is deservedly high, provided a fully developed account of basic cognition that pointed to key issues of societal explanation that preserved individualism, supporting a view of society as a spontaneous order, and also qualified his view of the social organism. Despite his great influence, this development was largely cut off when social scientists absorbed and transformed neo-Kantianism and combined it with Völkerpsychologie into a model of culture that transferred cognitive issues to the collective level. The later social psychological use of “attitude” as a surrogate for cognitive processes also blocked a cognitively based account of society, as proposed by sociologists like Charles Ellwood. (shrink)

One major milestone in the development of the sea urchin embryo is the assembly of a single cilium on each blastomere just before hatching. These cilia are constructed both from pre‐existing protein building blocks, such as tubulin and dynein, and from a number of 9+2 architectural elements that are synthesized de novo at ciliogenesis. The finite or quantal synthesis of certain key architectural proteins is coincident with ciliary elongation and proportional to ciliary length. Upon deciliation, the synthesis of architectural proteins (...) occurs anew, a new cilium grows, and the stores of various building blocks are replenished. This routine of coordinated ciliary gene expression may be replayed experimentally many times without delaying normal development. The ability to regenerate cilia has allowed elucidation of these various protein synthetic relationships and has led to the discovery of the pathways by which membrane‐associated tubulin and axoneme‐associated architectural proteins are conveyed into the highly compartmentalized growing cilium. The sea urchin embryo thus provides a very convenient model system for studies of ciliary assembly and maintenance, coordinate gene expression and membrane dynamics. (shrink)

The authors examined cue competition effects in young children using the blicket detector paradigm, in which objects are placed either singly or in pairs on a novel machine and children must judge which objects have the causal power to make the machine work. Cue competition effects were found in a 5- to 6-year-old group but not in a 4-year-old group. Equivalent levels of forward and backward blocking were found in the former group. Children's counterfactual judgments were subsequently examined by asking (...) whether or not the machine would have gone off in the absence of I of 2 objects that had been placed on it as a pair. Cue competition effects were demonstrated only in 5- to 6-year-olds using this mode of assessing causal reasoning. (shrink)

This document provides a vision of the communications-related aspects of the Smart Grid in the year 2030, and lays out the technology roadmap that will lead us to the vision. This document starts with some basic knowledge of the power grid and follows up with fundamental building blocks for the communication infrastructure that will accompany the Smart Grid. Subsequently, network architectures, including overlays, are discussed at length. Also discussed, are important issues such as standards, regulations, security, and disruptive technologies. The (...) last part of this document discusses emerging technologies such as the solid state transformer, wireless beamed power, and quantum key distribution. Throughout the document, a careful distinction is made between communications capabilities and the specific technologies that are required to support those capabilities. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 21.1 (2001) 147-151 [Access article in PDF] Book Review Philosophical Meditations on Zen Buddhism Philosophical Meditations on Zen Buddhism. By DaleS.Wright. Cambridge, Great Britain: Cambridge University Press, 1998. xv +227 pp. In a work brimming with unobtrusive erudition and centered on the figure of Huang Po (d. 850), Dale Wright offers a seasoned account of a topic that is still very much in need of clarification, namely, (...) the roles of language, conceptuality, textuality, interpretation, and historical development in Zen Buddhism. Some recent critics tend to see Zen as incoherent or even hypocritical in that this "special transmission outside the sutras, not dependent on language and texts, pointing directly to mind" (quoted, p. 64) in reality developed complex and varied textual and ritual traditions from [End Page 147] which the supposedly pure enlightenment experience cannot be siphoned out. Wright argues that the critics themselves are often naive, giving an inverted reflection of the naiveté of earlier scholars such as John Blofeld, who saw Zen as centered on an ineffable Supreme Experience, quite independent of the language used to point to it. Nonetheless, Wright himself is in basic agreement with the critics and in radical opposition to Blofeld (and to D. T. Suzuki). But he points out that the early Chinese Zen masters speak in many voices, often anticipating the most sophisticated insights of their critics.Wright's style is very unlike that of Bernard Faure, being slow, serene, reflective, scrupulous, and imbued with the deepest respect for the Zen tradition. Yet his thought rejoins Faure's at many points.The thrust of Wright's argument is to demystify Zen enlightenment by reinserting it in its varied linguistic, social, institutional, and historical contexts. He gives a realistic and holistic account of what Zen experience must have been like for disciples of Huang Po (pp. 187-192). His stress on the linguisticality of all experience certainly illuminates the texture of Huang Po's world. But I am left wondering if there is not another aspect of Zen that is missed here. Modern philosophers have derived much insight from the realization that thought and perception are deeply embedded in language. But I do not know that anyone has proven that there can never be a thinking or perception that is independent of language. Even the supposedly pan-textualist Derrida states somewhere that he does not exclude the possibility of nonlinguistic thought. In most fields of inquiry this abstruse question makes no practical difference, but in the case of Zen it is of crucial import. The presupposition of universal linguisticality, especially if it hardens into a dogma, may block access to the core of Zen experience.Wright argues that though some Zen masters sought prelinguistic immediacy, the majority were deeply aware of the inseparability of experience and the language in which it is grasped. But could it not be that prelinguistic immediacy was so much taken for granted in Zen that the masters scarcely needed to insist on it? Wright says that enlightenment itself is a linguistic event, since it is often occasioned by a verbal statement and given immediate expression in another verbal statement. But to recognize the indispensability of language for conveying experience is not necessarily to imply that the experience itself is dependent on language. Although a certain poem of Huang Po "strives to make its anti-textual point, the master must enter into the textual world to do so, thus abandoning the position of 'no dependence on texts'" (p. 22). Is it really necessary to see a contradiction here, given that, as Wright himself points out, "no unanimity on the meaning of the mandate against 'words and letters' existed" (p. 26)? Let us suppose that the point is nonattachment to texts and a realization of the intrinsic independence of enlightenment from the limited perspectives of textuality, language, and conceptual thought. This is quite compatible with intensive use of texts in practice.Blofeld explains that texts were useful to the learner but cast aside when enlightenment was reached. Wright argues that the enlightened experience must "continue to hold within it, and... (shrink)

What could someone represent that would enable her to track, at least within limits, others' perceptions, knowledge states and beliefs including false beliefs? An obvious possibility is that she might represent these very attitudes as such. It is sometimes tacitly or explicitly assumed that this is the only possible answer. However, we argue that several recent discoveries in developmental, cognitive, and comparative psychology indicate the need for other, less obvious possibilities. Our aim is to meet this need by describing the (...) construction of a minimal theory of mind. Minimal theory of mind is rich enough to explain systematic success on tasks held to be acid tests for theory of mind cognition including many false belief tasks. Yet minimal theory of mind does not require representing propositional attitudes, or any other kind of representation, as such. Minimal theory of mind may be what enables those with limited cognitive resources or little conceptual sophistication, such as infants, chimpanzees, scrub-jays and human adults under load, to track others' perceptions, knowledge states and beliefs. (shrink)

Pulvermüller's work in extending Hebb's theory into the realm of language is exciting. However, we feel that what he characterizes as a single cell assembly is actually a set of cooperating cell assemblies that form parts of larger cognitive structures. These larger structures account more easily for a variety of phenomena, including the psycholinguistic.

In lieu of an abstract, here is a brief excerpt of the content:Caught Between History and ImaginationVico's Ingenium for a Rhetorical Renovation of CitizenshipAlessandra Beasley Von BurgCitizenship is usually thought of as synonymous with nationality and the rights and duties associated with the people who live, work, and participate politically, socially, and economically within the borders of their nation-state. In this conception, the main criterion used to decide who is and who is not a citizen is nationality. As the nature (...) of nation-state governance evolves and the acceleration of citizen mobility hastens interdependence, pressures for new definitions and paradigms of citizenship build. As Joseph Weiler argues, this pressure produces cognitive dissonance because "the traditional, classical vocabulary of citizenship is the vocabulary of the State, the Nation and Peoplehood" (qtd. in La Torre 1998, 1).1 The classical association of citizenship with nationality blocks our ability to grasp new, nonstatist conceptions of citizenship, even as postnational political visions take shape in institutions like the European Union (EU).2 In 1992, EU citizenship was established in the Treaty of Maastricht, which granted some additional rights to citizens of the member states in the same way that single nation-states grant their inhabitants special status as nationals, rights that are not nullified when citizens leave their home country to live and work in other member states.3 [End Page 26]The relationship between nationality and citizenship in the EU context is complicated by the fact that although Maastricht guidelines set postnational membership criteria for EU citizens, they also limit the scope of EU citizenship. In trying to reach beyond the nation while anchoring its very essence to the nation, EU citizenship remains limited as it relies on the traditional language of national membership to found its postnational concept of equality and inclusion for noncitizens. The contradictory elements of EU citizenship are exemplified in its current definition, which includes all member states' citizens and excludes millions who are living in Europe as third-country nationals (TCNs), defined as "any person who is not a citizen of one of the member states" of the EU but permanently and legally resides in one.4 The current debate over the status of legal, long-term TCNs challenges the relationship between citizenship and nationality, as advocates from EU institutions, national governments, nongovernmental organizations and academia argue that TCNs should be granted EU citizenship rather than be naturalized in the member states and push for a new, postnational mode of citizenship based on residency. Advocates for the inclusion of TCNs as EU citizens have to work with the limited vocabulary of national citizenship yet articulate a case for a new kind of citizenship divorced from nationality. They suggest that the EU should be viewed as a deliberative community, in which all long-term residents like TCNs are given an equal opportunity to practice citizenship. The deliberative community rationale is based on an idea of citizenship as performance with residents enacting citizenship by living together and deliberating with each other about common interests and concerns.5This reordering of the concept of community arising out of political practice calls for a full philosophical and rhetorical reimagining of the meaning of citizenship. The act of reimagining citizenship creates a new practice of citizenship and grounds citizenship in a philosophical context as well as a practical one. There is no better philosophical and rhetorical tradition to turn to for this purpose than that of Giambattista Vico. Vico, and to a larger extent the entire tradition of Italian humanism, has been overlooked in modern Western philosophy. Yet Vico embodies a seamless marriage of philosophy and rhetoric. Vico's philosophically grounded rhetoric provides the means in an investigation of EU citizenship as an innovative rhetorical practice beyond nationality, for understanding how new practices become persuasive through imaginative language, until citizens separate citizenship from nationality and accept residence and deliberative practices as legitimate criteria for citizenship. Vico argues that "every study method [End Page 27] may be said to be made up of three things: instruments, complementary aids, and aim envisaged" and notes that "the instruments presuppose and include a systematic, orderly manner of proceeding" (1990, 6). This essay proceeds in this fashion to reveal how a new vocabulary of citizenship... (shrink)

Many of the things we do are, or could be, done with others. Mundane examples favoured by philosophers include painting a house together (Bratman 1992), lifting.

What could someone represent that would enable her to track, at least within limits, others' perceptions, knowledge states and beliefs including false beliefs? An obvious possibility is that she might represent these very attitudes as such. It is sometimes tacitly or explicitly assumed that this is the only possible answer. However, we argue that several recent discoveries in developmental, cognitive, and comparative psychology indicate the need for other, less obvious possibilities. Our aim is to meet this need by describing the (...) construction of a minimal theory of mind. Minimal theory of mind is rich enough to explain systematic success on tasks held to be acid tests for theory of mind cognition including many false belief tasks. Yet minimal theory of mind does not require representing propositional attitudes, or any other kind of representation, as such. Minimal theory of mind may be what enables those with limited cognitive resources or little conceptual sophistication, such as infants, chimpanzees, scrub‐jays and human adults under load, to track others' perceptions, knowledge states and beliefs. (shrink)

In this paper I offer an analysis of, and suggest some methods for dealing with, a quite particular and peculiar problem in teaching philosophy. It is, perhaps,not a problem essential to the discipline or to its teaching, but it is nevertheless one of the most serious, pervasive, and frustrating problems confronting mostphilosophy teachers today. I speak of the problem of student relativism-or, SR for short.

The development of children’s minds raises fundamental psychological and scientific questions, from how we are able to know about and describe basic aspects of the world such as words, numbers and colours to how we come to grasp causes, actions and intentions. This is the first book to properly introduce and examine philosophical questions concerning children’s cognitive development and considers the implications of scientific breakthroughs for the philosophy of developmental psychology. Each chapter explores a central topic in developmental psychology from (...) a philosophical perspective: social interaction and the developing mind children's awareness of objects and the question of 'object permanence' knowledge of numbers children and the acquisition of knowledge of colour language acquisition and the 'mapping problem' children's knowledge of the relation between actions and goals belief acquisition and the developing mind. Throughout the book Stephen Butterfill draws on several important case studies, including experiments with children on memory, ‘false belief tasks’, and the process by which children come to see other people, not just themselves, as capable of experience. He shows how these questions can illuminate some fundamental debates in philosophy of mind, such as the mind’s possession of concepts, rationality and the mind, the possibility of objective thought, and the nature of perceptual experience. Additional features, such as chapter summaries, annotated further reading and a glossary provide helpful tools for those coming to the subject for the first time. (shrink)

What is Christian about Christian bioethics? And is an authentically Christian bioethics a practical possibility in the world in which we find ourselves? In my essay I argue that personhood and the personal are so fundamental to the Christian understanding of our humanity that body, soul, and spirit are probably best understood as the components of a triune (as opposed to dual) aspect theory of personhood. To confess to a Christian bioethics is to admit that Christians cannot pretend fully to (...) understand either cures or their meaning. However effective and “knowledge-based” contemporary medical interventions are, a Christian must humbly and honestly confess a lack of complete knowledge on both levels. At the same time, a Christian bioethicist must express a total personal commitment to Christian Faith. (shrink)

Amit's efforts to provide stronger theoretical and empirical support for Hebb's cell-assembly concept is admirable, but we have serious reservations about the perspective presented in the target article. For Hebb, the cell assembly was a building block; by contrast, the framework proposed here eschews the need to fit the assembly into a broader picture of its function.

Three experiments investigated response times for remember and know responses in recognition memory. RTs to remember responses were faster than RTs to know responses, regardless of whether the remember–know decision was preceded by an old/new decision or was made without a preceding old/new decision . The finding of faster RTs for R responses was also found when remember–know decisions were made retrospectively. These findings are inconsistent with dual-process models of recognition memory, which predict that recollection is slower and more effortful (...) than familiarity. Word frequency did not influence RTs, but remember responses were faster for words than for nonwords. We argue that the difference in RTs to remember and know responses reflects the time taken to make old/new decisions on the basis of the type of information activated at test. (shrink)

In this response to the commentary by Michael and Christensen, we first explain how minimal mindreading is compatible with the development of increasingly sophisticated mindreading behaviours that involve both executive functions and general knowledge, and then sketch one approach to a minimal account of goal ascription.

The unique discourse of Confucian ritual practice encompasses a powerful and sophisticated way of talking about individual fulfillment within the context of more substantive or universal conceptions of the good life. To make this case, I will consider both the text of the "Analects" and the influential readings of the "Analects" offered by Fingarette in "Confucius: The Secular as Sacred" and by Hall and Ames in "Thinking through Confucius". Though the two interpretive works are helpful in articulating the classical Confucian (...) contribution to the problem of balancing conformity and individuality, I will argue that an alternative reading is required to appreciate fully how values thought to embody and express the fullest humanity might be inculcated in ethical agents without undoing their individuality. Such an alternative is developed here. (shrink)

Scientific peer reviewers play an integral role in the grant selection process, yet very little has been reported on the levels of participation or the motivations of scientists to take part in peer review. The American Institute of Biological Sciences developed a comprehensive peer review survey that examined the motivations and levels of participation of grant reviewers. The survey was disseminated to 13,091 scientists in AIBS’s proprietary database. Of the 874 respondents, 76% indicated they had reviewed grant applications in the (...) last 3 years; however, the number of reviews was unevenly distributed across this sample. Higher review loads were associated with respondents who had submitted more grant proposals over this time period, some of whom were likely to be study section members for large funding agencies. The most prevalent reason to participate in a review was to give back to the scientific community and the most common reason to decline an invitation to review was lack of time. Interestingly, few suggested that expectation from the funding agency was a motivation to review. Most felt that review participation positively influenced their careers through improving grantsmanship and exposure to new scientific ideas. Of those who reviewed, respondents reported dedicating 2–5% of their total annual work time to grant review and, based on their self-reported maximum review loads, it is estimated they are participating at 56–87% of their capacity, which may have important implications regarding the sustainability of the system. Overall, it is clear that participation in peer review is uneven and in some cases near capacity, and more needs to be done to create new motivations and incentives to increase the future pool of reviewers. (shrink)