Complex Systems Biology approaches are here considered from the viewpoint of Robert Rosen’s (M,R)-systems, Relational Biology and Quantum theory, as well as from the standpoint of computer modeling. Realizability and Entailment of (M,R)-systems are two key aspects that relate the abstract, mathematical world of organizational structure introduced by Rosen to the various physicochemical structures of complex biological systems. Their importance for understanding biological function and life itself, as well as for designing new strategies for treating diseases (...) such as cancers, is pointed out. The roles played by multiple metastable states in the “continuous uphill flow of Life” supported through internal bioenergetic processes that are coupled to essential inflows are also discussed in relation to dynamic realizations of (M,R)-systems. Furthermore, the roles played by the underlying, many-valued, quantum logics and symbolic computations for ultra-complex biological systems are also briefly discussed. (shrink)

The known facts of quantum physics and biology strongly suggest the following hypotheses: atoms and the fundamental particles have a rudimentary degree of consciousness, volition, or self-activity; the basic features of quantum mechanics are a result of this fact; the quantum mechanical wave properties of matter are actually the conscious properties of matter; and living organisms are a direct result of these properties of matter. These hypotheses are tested by using them to make detailed predictions of (...) new facts, and then by showing that the predictions can be verified. The hypotheses are used to predict successfully that the quantum wave properties of matter are strongly predominant in proteins, to explain the presence and relative abundance of carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur in proteins, and to explain diffraction phenomena, the behavior of helium II, the exclusion principle, and causality and determinism in modern science, thus closely relating physics and biology. (shrink)

Linear temporal logic is a widely used method for verification of model checking and expressing the system specifications. The relationship between theory of automata and logic had a great influence in the computer science. Investigation of the relationship between quantum finite automata and linear temporal logic is a natural goal. In this paper, we present a construction of quantum finite automata on finite words from linear-time temporal logic formulas. Further, the relation between quantum finite (...) automata and linear temporal logic is explored in terms of language recognition and acceptance probability. We have shown that the class of languages accepted by quantum finite automata are definable in linear temporal logic, except for measure-once one-way quantum finite automata. (shrink)

This article seeks to clarify the relation between consciousness and quantum physics. It is argued that, in order to be consistent with quantum theory, one must never assert that conscious action has caused a given event to occur. Rather, consciousness must be identified with "measurement" or, more concretely, with an increase in the entropy of the probability distribution of possible events. It is suggested that the feeling of self-awareness may be associated with the exchange of entropy between groups (...) of quantum systems which are so tightly coupled as to be, for all practical purposes, an indivisible unit. Such groups of systems may be understood to measure themselves. Two interpretations of the quantum theory of consciousness are distinguished: one in which consciousness is defined as quantum measurement; and one in which this measurement is hypothesized to correlate with a certain biological phenomenon called consciousness. (shrink)

In the author’s previous contribution to this journal (Rosen 2015), a phenomenological string theory was proposed based on qualitative topology and hypercomplex numbers. The current paper takes this further by delving into the ancient Chinese origin of phenomenological string theory. First, we discover a connection between the Klein bottle, which is crucial to the theory, and the Ho-t’u, a Chinese number archetype central to Taoist cosmology. The two structures are seen to mirror each other in expressing the psychophysical (phenomenological) action (...) pattern at the heart of microphysics. But tackling the question of quantum gravity requires that a whole family of topological dimensions be brought into play. What we find in engaging with these structures is a closely related family of Taoist forebears that, in concert with their successors, provide a blueprint for cosmic evolution. Whereas conventional string theory accounts for the generation of nature’s fundamental forces via a notion of symmetry breaking that is essentially static and thus unable to explain cosmogony successfully, phenomenological/Taoist string theory entails the dialectical interplay of symmetry and asymmetry inherent in the principle of synsymmetry. This dynamic concept of cosmic change is elaborated on in the three concluding sections of the paper. Here, a detailed analysis of cosmogony is offered, first in terms of the theory of dimensional development and its Taoist (yin-yang) counterpart, then in terms of the evolution of the elemental force particles through cycles of expansion and contraction in a spiraling universe. The paper closes by considering the role of the analyst per se in the further evolution of the cosmos. (shrink)

Recent advances on quantum foundations achieved the derivation of free quantum field theory from general principles, without referring to mechanical notions and relativistic invariance. From the aforementioned principles a quantum cellular automata theory follows, whose relativistic limit of small wave-vector provides the free dynamics of quantum field theory. The QCA theory can be regarded as an extended quantum field theory that describes in a unified way all scales ranging from an hypothetical discrete Planck scale (...) up to the usual Fermi scale. The present paper reviews the automaton theory for the Weyl field, and the composite automata for Dirac and Maxwell fields. We then give a simple analysis of the dynamics in the momentum space in terms of a dispersive differential equation for narrowband wave-packets. We then review the phenomenology of the free-field automaton and consider possible visible effects arising from the discreteness of the framework. We conclude introducing the consequences of the automaton dispersion relation, leading to a deformed Lorentz covariance and to possible effects on the thermodynamics of ideal gases. (shrink)

In the present paper, I shall argue that quantum theory can contribute to reconciling evolutionary biology with the creation hypothesis. After giving a careful definition of the theological problem, I will, in a first step, formulate necessary conditions for the compatibility of evolutionary theory and the creation hypothesis. In a second step, I will show how quantum theory can contribute to fulfilling these conditions. More precisely, I claim that (1) quantum probabilities are best understood in terms (...) of ontological indeterminism, but (2) reflect nevertheless causal openness rather than divine indifference or arbitrariness, and (3) such a genuinely creative universe can be considered as the work of a loving Creator. I ask subsequently whether these necessary conditions are also sufficient for the compatibility of evolutionary theory and the creation hypothesis. Finally, I will show that relating evolutionary biology with theology via quantum theory could also shed some light on the nature of life. (shrink)

This paper explores the similarities between the conceptual structure of quantum theory and relational biology as developed within the Rashevsky-Rosen-Louie school of theoretical biology. With this aim, generalized quantum theory and the abstract formalism of (M,R)-systems are briefly presented. In particular, the notion of organizational invariance and relational identity are formalized mathematically and a particular example is given. Several quantum-like attributes of Rosen’s complex systems such as complementarity and nonseparability are discussed. Taken together, (...) this work emphasizes the possible role of self-referentiality and impredicativity in quantum theory. (shrink)

Wolfgang Pauli is known as one of the most famous physicists of the 20th century. Next to an intensive treatment of physics, his impressive correspondence with fellow physicists also demonstrates a vivid interest in psychology and biology. Reflections on the mind-brain problem and on topics such as causality and evolutionary theory are readily present. In this paper, some central passages in this correspondence are discussed and linked to more current debates in philosophy of science and philosophy of biology. (...) It is shown how Pauli speculatively explored how evolutionary theory can find inspiration in quantum theory and in its related concept of observer-dependency. Contra Kalervo Laurikainen's interpretation, it is argued that Pauli's criticism remains true to a naturalistic view on science and biology. (shrink)

The fracture in the emerging discipline of biosemiotics when the code biologist Marcello Barbieri claimed that Peircian biosemiotics is not genuine science raises anew the question: What is science? When it comes to radically new approaches in science, there is no simple answer to this question, because if successful, these new approaches change what is understood to be science. This is what Galileo, Darwin and Einstein did to science, and with quantum theory, opposing interpretations are not merely about what (...) theory is right, but what is real science. Peirce's work, as he acknowledged, is really a continuation of efforts of Schelling to challenge the heritage of Newtonian science for the very good reason that the deep assumptions of Newtonian science had made sentient life, human consciousness and free will unintelligible, the condition for there being science. Pointing out the need for such a revolution in science has not succeeded as a defence of Peircian biosemiotics, however. In this paper, I will defend the scientific credentials of Peircian biosemiotics by relating it to the theoretical biology of the bio-mathematician, Robert Rosen. Rosen's relational biology, focusing on anticipatory systems and giving a place to final causes, should also be seen as a rigorous development of the Schellingian project to conceive nature in such a way that the emergence of sentient life, mind and science are intelligible. Rosen has made a very strong case for the characterization of his ideas as a real advance not only in science, but in how science should be understood, and I will argue that it is possible to provide a strong defence of Peircian biosemiotics as science through Rosen's defence of relational biology. In the process, I will show how biosemiotics can and should become a crucial component of anticipatory systems theory. (shrink)

Generalized Quantum Theory seeks to explain and predict quantum-like phenomena in areas usually outside the scope of quantum physics, such as biology and psychology. It draws on fundamental theories and uses the algebraic formalism of quantum theory that is used in the study of observable physical matter such as photons, electrons, etc. In contrast to quantum theory proper, GQT is a very generalized form that does not allow for the full application of formalism. For (...) instance neither a commutator, such as Planck’s constant, nor any additive operations are defined, which precludes the usage of a full Hilbert-space formalism. But it is a formalized phenomenological theory that is applicable whenever the core element of a quantum theory needs to be captured, namely in the presence of incompatible or non-commuting operations. As a consequence, it also predicts nonlocal, generalized entanglement correlations in systems other than proper quantum systems. In this paper we summarize the specific scientific evidence relating to the quantum-like mental, behavioral and physiological nonlocal correlations. Such non-local, generalized entanglement correlations are expected, both in space and time, between subsystems of a larger system, whenever observables pertaining to the global system are incompatible or complementary to observables pertaining to subsystems, as predicted by GQT. The result is a coherent explanation of a significant amount of controversial and seemingly weird occurrences that cannot be explained by classical physical laws. This review also offers a new perspective of the human mind’s potential. (shrink)

By the relational realist interpretation of wave function collapse, the quantum mechanical actualization of potentia is defined as a decoherence-driven process by which each actualization (in “orthodox” terms, each measurement outcome) is conditioned both by physical and logical relations with the actualities conventionally demarked as “environmental” or external to that particular outcome. But by the relational realist interpretation, the actualization-in-process is understood as internally related to these “enironmental” data per the formalism of quantum decoherence. The concept (...) of “actualization via wave function collapse” is accounted for solely by virtue of these presupposed logical relations—the same logical relations otherwise presupposed by the scientific method itself—and thus requires no “external” physical-dynamical trigger: e.g., the Gaussian hits of GRW, acts of conscious observation, etc. By the relational realist interpretation, it is the physical and logical relations among quantum actualities (quantum “final real things”) that drives the process of decoherence and, via the latter, the logically conditioned actualization of potentia. In this regard, the relational realist interpretation of quantum mechanics is a praxiological interpretation; that is, these physical and logical relations are ontologically active relations, contributing not just to the epistemic coordination of quantum actualizations, but to the process of actualization itself. (shrink)

Relations occur on all levels of systems. Following a major assumption of generalized quantum theory, namely that the principles of quantum mechanics will occur on higher system levels as well, it was investigated in an a posteriori analysis of pre-existing data whether relational patterns found for two-photon experiments are similarly performed by two cell-populations. In particular, the typical pattern in outcomes of two-photon entanglement experiments was extrapolated to discover similar patterns of relationships in the cellular biological system (...) of the Ciliate Paramecium caudatum. In the former case we find one photon assuming a particular state when being measured and the other assuming a correlated state with regard to the first particle. From a perspective of degrees of freedom (df) the author interprets this outcome as follows: Each particle has only one df for assuming a particular state (e.g. its spin). When measured this is leading to a pattern: They use their two degrees of freedom for establishing a relation among them (particle-to-particle) and for a relation with the environment (particle-to-measurement). If this pattern is unique then we should find it also in cell-to-cell relationships. It was suggested to consider causations in cell-to-cell relations as the analogue to the relationship between the quantum particles (see above) and the dependence of repeating the experiments as the analogue to the measurement event in the quantum experiment. It was hypothesized that in a relational system of two cell populations only one should be sensitive to the repetition of the experiment. The other population, however, should establish a relation with the first one. Since the author had successfully performed experiments with pairs of cell populations that were separated with glass barriers from each other but having effects on each other (Fels in PLoS One 4:e5086, 2009), the system was perfectly well suited for testing the hypothesis. The assessed cell variable was cell division. An a posteriori analysis of three similar experiments confirmed that when populations were in a relation with each other, only one of them stood in relation with the repetition of the experiment. (shrink)

Non‐Interventionist Objective Divine Action (NIODA), introduced by Robert John Russell, is a model of divine action drawing upon insights from quantum mechanics. It presents an intriguing and significant challenge to classical conceptions of divine action with far‐reaching consequences. When applying NIODA to theistic evolution, however, significant questions emerge that require attention. We identify and assess two sets of concerns. The first relates to quantum physics, particularly whether and how quantum occurrences influence mutations and evolution. We argue that (...) the current empirical evidence is ambiguous in its support of the kinds of quantum action that Russell proposes, though emerging data from quantum biology look promising. The second set of concerns is metaphysical, especially concerning the problem of evil. NIODA gives Godextensive agency over evolution and genetics, which has adverse consequences for theodicy. We propose potential solutions to the problems highlighted in our article, both metaphysical and physical, to improve the viability of NIODA's application to theistic evolution. (shrink)

The notion of an instrument in the quantum theory of measurement is studied in the context of transformation valued linear maps on von Neumann algebras and their *-subalgebras. An extension theorem is proved which yields among other things characterizations of the Fourier transforms of instruments and their noncommutative analogues. As an application, an ergodic type theorem for a general class of transformation valued functions on a locally compact group is obtained.

The hard problem of consciousness is the question how subjective experience arises from brain matter. I suggest that quantum physics may be part of the answer. The simultaneous unity and complexity of subjective experience is very difficult to understand from a classical physics perspective. In contrast, quantum entanglement is naturally both complex and holistic. Building on recent remarkable progress in quantum technology and neuroscience, I propose a concrete hypothesis as a basis for further investigation, namely that subjective (...) experience is related to the dynamics of a complex entangled state of spins, which is continuously generated and updated through the exchange of photons. The proposed hypothesis raises many interesting experimental and theoretical questions in neuroscience, quantum physics, evolutionary biology, psychophysics, and philosophy. (shrink)

Symmetries play a major role in physics, in particular since the work by E. Noether and H. Weyl in the first half of last century. Herein, we briefly review their role by recalling how symmetry changes allow to conceptually move from classical to relativistic and quantum physics. We then introduce our ongoing theoretical analysis in biology and show that symmetries play a radically different role in this discipline, when compared to those in current physics. By this comparison, we (...) stress that symmetries must be understood in relation to conservation and stability properties, as represented in the theories. We posit that the dynamics of biological organisms, in their various levels of organization, are not just processes, but permanent (extended, in our terminology) critical transitions and, thus, symmetry changes. Within the limits of a relative structural stability (or interval of viability), variability is at the core of these transitions. (shrink)

The feasibility of establishing a proper notion of a distinguishable object in the context of the de Broglie–Bohm approach to quantum mechanics seems, at first sight, uncontroversial by virtue of the fact that this theory can supposedly be interpreted in terms of a system of objective particles distinguished by individuating properties. However, after conducting a critical revision and evaluation of this trivial interpretation, and having assessed different alternatives that have been proposed in recent literature, I argue that within this (...) theory an appropriate notion of a distinguishable object can only be articulated by means of the following theoretical and metaphysical strategies: firstly, by appealing to a pre-existing, symmetrized Bohmian framework that is empirically indistinguishable but physically distinguishable from the standard Bohmian formulation; and secondly, by suggesting a different interpretation of this symmetrized formulation based upon a relational notion of the distinguishable object that can only be appropriately conceived from a structuralist point of view. (shrink)

In some recent papers (G. ‘t Hooft and others), it has been argued that quantum mechanics can arise from classical cellular automata. Nonetheless, G. Shpenkov has proved that the classical wave equation makes it possible to derive a periodic table of elements, which is very close to Mendeleyev’s one, and describe also other phenomena related to the structure of molecules. Hence the classical wave equation complements Schrödinger’s equation, which implies the appearance of a cellular automaton molecular model starting (...) from classical wave equation. The other studies show that the microworld is constituted as a tessellation of primary topological balls. The tessellattice becomes the origin of a submicrospic mechanics in which a quantum system is subdivided to two subsystems: the particle and its inerton cloud, which appears due to the interaction of the moving particle with oncoming cells of the tessellattice. The particle and its inerton cloud periodically change the momentum and hence move like a wave. The new approach allows us to correlate the Klein-Gordon equation with the deformation coat that is formed in the tessellatice around the particle. The submicroscopic approach shows that the source of any type of wave movements including the Klein-Gordon, Schrödinger, and classical wave equations is hidden in the tessellattice and its basic exciations – inertons, carriers of mass and inert properies of matter. We also discuss possible correspondence with Konrad Zuse’s calculating space. (shrink)

Standard quantum mechanics unquestionably violates the separability principle that classical physics (be it point-like analytic, statistical, or field-theoretic) accustomed us to consider as valid. In this paper, quantum nonseparability is viewed as a consequence of the Hilbert-space quantum mechanical formalism, avoiding thus any direct recourse to the ramifications of Kochen-Specker’s argument or Bell’s inequality. Depending on the mode of assignment of states to physical systems – unit state vectors versus non-idempotent density operators – we distinguish between strong/ (...) class='Hi'>relational and weak/deconstructional forms of quantum nonseparability. The origin of the latter is traced down and discussed at length, whereas its relation to the all important concept of potentiality in forming a coherent picture of the puzzling entangled interconnections among spatially separated systems is also considered. Finally, certain philosophical consequences of quantum non-separability concerning the nature of quantum objects, the question of realism in quantum mechanics, and possible limitations in revealing the actual character of physical reality in its entirety are explored. (shrink)

Originally published in 1979. This reprints the revised and expanded edition of 1996. In this volume, physicists, biologists and chemists, who have been involved in some of the most exciting discoveries in modern scientific thought explore issues which have shaped modern physics and which hint at what may form the next scientific revolution. The major issues discussed are the understanding of time and space, quantum and relativity theories and recent attempts to unite them and related questions in theoretical (...) class='Hi'>biology. (shrink)

In "The Indeterministic Character of Evolutionary Theory: No 'Hidden Variables Proof' But No Room for Determinism Either," Brandon and Carson (1996) argue that evolutionary theory is statistical because the processes it describes are fundamentally statistical. In "Is Indeterminism the Source of the Statistical Character of Evolutionary Theory?" Graves, Horan, and Rosenberg (1999) argue in reply that the processes of evolutionary biology are fundamentally deterministic and that the statistical character of evolutionary theory is explained by epistemological rather than ontological considerations. (...) In this paper I focus on the topic of mutation. By focusing on some of the theory and research on this topic from early to late, I show how quantum indeterminism hooks up to point mutations (via tautomeric shifts, proton tunneling, and aqueous thermal motion). I conclude with a few thoughts on some of the wider implications of this topic. (shrink)

Over the past half-century, the Freeman laboratory has accumulated a large volume of data and a correspondingly extensive interpretive framework centered around an alternative perspective on brain function, that of dynamical systems. The purpose of this paper is first briefly to summarise this work, and bring it into dialogue with other perspectives. The contents of consciousness are seen as an inevitably sparse sample of events in the perception–action cycle. The paper proceeds to an attempt to elucidate the contents of this (...) sparse sample. A critical concept is that of selfhood, and how it presents itself phenomenologically. It is argued that our experience of selfhood is an artifact of the necessity of preservation of subject/object relations. As this part of metaphysics has been badly misunderstood, we scrutinise it at some length in quantum mechanics, biology, and cognition. It is argued that Pattee's approach, while valuable, tends to premature closure on these issues. The paper then proceeds to outline a view on how selfhood is best considered wrt the immune response. This is interrelated with phenomenology, and some data are adduced to support this central hypothesis. Finally, consequences for the social sciences in general are hinted at. (shrink)

We argue that genuine biological autonomy, or described at human level as free will, requires taking into account quantum vacuum processes in the context of biological teleology. One faces at least three basic problems of genuine biological autonomy: (1) if biological autonomy is not physical, where does it come from? (2) Is there a room for biological causes? And (3) how to obtain a workable model of biological teleology? It is shown here that the solution of all these three (...) problems is related to the quantum vacuum. We present a short review of how this basic aspect of the fundamentals of quantum theory, although it had not been addressed for nearly 100 years, actually it was suggested by Bohr, Heisenberg, and others. Realizing that the quantum mechanical measurement problem associated with the “collapse” of the wave function is related, in the Copenhagen Interpretation of quantum mechanics, to a process between self-consciousness and the external physical environment, we are extending the issue for an explanation of the different processes occurring between living organisms and their internal environment. Definitions of genuine biological autonomy, biological aim, and biological spontaneity are presented. We propose to improve the popular two-stage model of decisions with a biological model suitable to obtain a deeper look at the nature of the mind-body problem. In the newly emerging picture biological autonomy emerges as a new, fundamental and inevitable element of the scientific worldview. (shrink)

In The Logic of Life, François Jacob reconstructed the history of heredity from the seventeenth century to the present, emphasizing the role of physics in the development of biology. Quantum mechanics provided questions, methods, and techniques to molecular biologists. In the 1960s, physics also provided the organizational model. Jacob worked on the creation of the European Molecular Biology Laboratory, on the model of CERN (European Organization for Nuclear Research). I argue that reflection on the relation between molecular (...) biology and physics played a part in the making of The Logic of Life. Between the mid-1960s and the early 1970s, Jacob focused on relations between the “genealogy” of his molecular biology work and the development of physics at scientific, institutional, and historical levels. He thus brought molecular biology to the attention of a larger public, following the history of the Institut Pasteur, whose public mission had to be reaffirmed to grant its survival. With The Logic of Life, Jacob became an influential intellectual who engaged with scholars in human sciences. He promoted his view of the development of molecular biology as a model for a possible new discipline: bioanthropology. (shrink)

This paper explores the relevance of the theology of Paul Tillich for the contemporary dialogue with the natural sciences. The focus is on his Systematic Theology, volume I. First I discuss the general relevance of Tillich's methodology (namely, the method of correlation) for that dialogue, stressing that a genuine dialogue requires cognitive input from both sides and that both sides find “value added” according to their own criteria (or what I call the method of “mutual creative interaction”). Then I move (...) specifically to a Tillichian theological analysis of twentieth‐century theoretical science and its empirical discoveries, including Big Bang, inflationary, and quantum cosmologies, quantum physics, thermodynamics, chaos and complexity, and molecular and evolutionary biology, suggesting how they relate to such Tillichian themes as finitude and the categories of being and knowing (time, space, causality, and substance) and to Tillich's understanding of such symbols as God, freedom and destiny, creation, and estrangement. In doing so, my intention is to provide a point of departure for further extended analyses of Tillich's theology in relation to contemporary natural science. (shrink)

Quantum decoherence is receiving a great deal of attention today not only in theoretical and experimental physics but also in branches of science as diverse as molecular biology, biochemistry, and even neuropsychology. It is no surprise that it is also beginning to appear in various philosophical debates concerning the fundamental structure of the world. The purpose of this article is primarily to acquaint non-specialists with quantum decoherence and clarify related concepts, and secondly to sketch its possible implications (...) – independent of particular interpretations of quantum mechanics – for broader philosophical debates. For example, decoherence shows that any method of parsing nature into levels or parts cannot be in principle but instead derives from our perception of the world as classical, a perception that is itself sustained by the process of decoherence. (shrink)

Methods developed in a previous paper are employed to define an exact correspondence between the states of a deterministic cellular automaton in 1+1 dimensions and those of a bosonic quantum field theory. The result may be used to argue that quantum field theories may be much closer related to deterministic automata than what is usually thought possible.

This study analyzes the triple relation between cognitive biological psychology, philosophy and quantum mechanics. It discusses the findings of Treisman according to which there exists a pre-conscious cerebral mechanism that manipulates the sensory input and transfers it to our consciousness only after correcting it to suit our logic and expectations. This experimental finding was predicted two centuries ago by Kant. It is observed that during the primary pre-conscious level of perception the macroscopic physical world is not perceived as behaving (...) according to the laws of classical physics but rather according to the laws of quantum mechanics, like the microscopic world. (shrink)

In classical physics, the world is considered as a matter-based reality, the arrangement of whose parts in time is uniquely determined by certain dynamic laws. By contrast, modern quantum physics reveals that matter is not composed of matter, but reality is merely potentiality. The world has a holistic structure, which is based on fundamental relations and not material objects, admitting more open, indeterministic developments. In this more flexible causal framework, inanimate and animate matter are not to be considered as (...) fundamentally different but as different order structures of the same immaterial entity. In a stable configuration, effectively all the uncertainties are statistically averaged out, thus the unique and deterministic behavior of ordinary inanimate matter is exhibited; whereas in the case of statically unstable but dynamically stable configurations, the “lively” features of the underlying quantum structure have a chance to surface to the mesocopic level and to be connected with what we observe as the phenomenon of life. This supposition can be more explicitly treated and clarified by identifying the electric dipole moment of biomolecules as the ordering parameter of the corresponding macroquantum system. This has important consequences for biology and medicine. In particular, it suggests the existence of a quantum-based “software,” essential perhaps for the logistics of biological processes, which are hidden behind the matter/energy-based “hardware” that alone is considered in the conventional approach. In medicine it opens an opportunity to build bridges between conventional medicine based essentially on the classical paradigm, and the various forms of complementary medicine, which have strong affinities with the new features of the modern holistic worldview. (shrink)

Tranquillity’s Secret Presents A New Understanding Of The World And Ourselves, And A Forgotten Meditation Technique That Protects You From Traumatic Harm. There Is A Way Of Seeing The World Different. -/- My goal in this book is two-fold: to introduce a revolutionary paradigm for understanding ourselves and the world; and to explain an ancient meditation technique that brought me to the insights upon which it is founded. This technique appears in different forms in the extant spiritual and religious traditions (...) over millennia which have used it — and in which it has been acknowledged as the most efficacious way to reach a direct experience of mind, or the most direct path to a union with God. Unfortunately, the proper way to use it has been largely lost over the last few centuries along with a clear understanding of why it was claimed to be so highly efficient. The primary reason for this loss is the mechanical materialism that frames all our scientific knowledge today. Lady Anne Conway, an English philosopher and a contemporary of René Déscartes, the French Metaphysician of the Seventeenth Century, was the first to characterize his philosophy as the “Mechanical philosophy.” It was Déscartes’ fascination with garden automata (moving statues) that he saw throughout Paris during his time, that led to his idea that the bodies of animals are nothing more than machines of varying complexity – which could be replaced by metal cogs, axles, and wheels. This very contemporary idea is in fact his legacy to humanity — along with the mind-body split that it entails — as mechanism became the standard to which Nature and all life was compared, and still is. This was the genesis of the modern reductive scientific understanding of life as discovered mechanisms made up of dead matter. -/- Although Déscartes’ philosophy was not materialism proper, as he held mind to not be material in nature, his was the most significant move to a cognitive framing of all phenomena as the result of mechanical interactions, and he went so far as placing all non-human animals into the machine-only category, because, he argued, they didn’t have minds. While a full account of Déscartes’ thought is not useful in this work, I want to use Lady Conway’s term to make a distinction between a mechanical materialism, which materialism has evolved into, and a less severe understanding that is not so destructive of the primacy of two aspects of being alive — mind and cognizance — which today are asserted to be by-products or epiphenomena of material processes in the brain by strict adherents to the mechanical philosophy. -/- This frame allows nothing but dead matter, and all that is comprised of dead matter, to be entertained as real. Anything beyond that is either ignored, or considered to be nothing more than figments of someone’s imagination — and this both limits and structures our thoughts about everything. Even those who believe they have moved on from this limiting understanding continue to be fenced in by language, which is structured by it — so that there is no escaping its limitations via a simple substitution or redefinition of concepts. Rather, it will take a truly revolutionary new paradigm and a concomitant reframing of our understanding of ourselves, this world, and reality, and how they come together in the new paradigm. I characterize the difficulty of this change as being like that of meeting an alien race and trying to work out how they see reality before communication can begin — which is very difficult to do when one’s own view is so limited. -/- I call this revolutionary paradigm Responsive Naturing. -/- Responsive Naturing replaces the current paradigm and its concomitant idea of deterministic causality which is foundational in scientific practice today. It can do this because, as you will see, it better accounts for all categories of phenomena, and thus includes all the most important human experiences, such as that of being alive, of beauty, of love, and the ultimate unity of all things. Responsive Naturing provides a sound foundation for the sciences, without the imposed limitation of mechanical materialist explanations, so that both science and spirituality can be founded upon this single common understanding of how things work. -/- This novel paradigmatic understanding of reality intrinsically applies to all dimensions of mental phenomena — be it of perceptions, sensations, or thoughts — and from the indeterminacy of quantum mechanics to the stochastic nature of most physical phenomena, to the often accidental, sometimes fortunate, but never sure, character of all human activities. This makes this new paradigm immediately productive in a practical way — it simply works, as I will show. It empowers us in ways that our disjointed and parochial schools of thought lock us out of completely, opening up new possible methods of looking at problems and finding solutions across disciplines. However, understanding the repercussions of the new paradigm upon one’s cognitive frame and the concomitant structure of language is difficult to comprehend simply because it is alien to the existing frame and paradigm. The impetus to make the effort is becoming quite clear: -/- Today, the sciences are ruled by the limiting cognitive framing of mechanical materialism, and over the last century, the limitations of that frame and its associated scientific paradigm of physical causality have become obvious: science has become schizophrenic. On one hand, some scientists say everything is strictly determined by the laws of nature, and neither free will nor conscious intent have any involvement in what happens; but others say that the state of the underlying quanta that make-up everything is indeterminate until consciously observed with the intent to measure it. Mechanical materialism is why scientists say you have no free will, while you obviously experience that you do — and you are held responsible for your actions by society because you do. It is also why scientists cannot find a non-speculative explanation of consciousness on an evolutionary or biological level, even though being conscious is the most obvious aspect of being alive. And these contradictions have infected every aspect of our lives, and our world, by limiting our ability to see the world any other way. Even the formulation of spiritual doctrines is constrained today by this cognitive frame’s presence in our language. This is not an academic matter, as we see clearly in our failure, so-far, to change the path that has brought us to a global environmental collapse and the ecocide of life on Earth. -/- What is unique about the book’s approach is that it does not speculate about what might be the case, like so much of philosophy does. Instead, it relies upon meditative and contemplative insights that were gleaned directly from a dedicated advanced meditation practice over 60+ years of the author’s life. These insights were then confirmed by subsequent research into similar forms of this advanced meditation technique found across the world and throughout human history. In conjunction with my meditation practice, I have doctoral-level education in Philosophy and a 30-year career in Software Engineering. The latter was in part focused on automated software development, during which I was confronted with the unsolvable enigma — within the mechanical materialist understanding that I was enculturated into, and inculcated with — of Human Creativity. An enigma that set me on my path of discovery. -/- I have discovered, and continue to discover, just how productive this novel paradigm is in understanding ourselves and our world, by its ability to explain — in detail — so many of our experiences that are today either inexplicable, paradoxical, or ignored “for the present” by scientists until some hoped for mechanical description can be found. For the most part, scientists constrain themselves to describing mechanisms, but describing how is not explaining why — and that is why so much of our modern knowledge has a best-used-by-date. On the other side, seemingly all spiritual traditions accept this modern characterization of the world, ourselves, and reality that is manifest in our language, so that even spiritual phenomena and ideas are necessarily structured by it. We accept the ideas of separate beings, intentional entities, levels of consciousness, and attainment of enlightenment or unification with God, all of which are necessary because dead matter, and unconsciousness, are considered to be the starting point. It isn’t. Rather than just present this novel paradigm as a fait accompli, the book’s five sections bring the reader through stages of reconfiguration of our understanding: -/- Volume 1. The Way of Unsaying — The need for the articles in the first volume is not to tell the reader how things are, but to unsay the things that they have heard throughout their lives and have taken to heart. This is accomplished by exposing the logical and explanatory limitations of those ideas that usually go unnoticed. This is necessary to do in order to open the reader’s mind to other ways of accounting for phenomena, and navigating life, so that the reader will understand: first, why the meditation technique I will present is so effective; and second, why the novel paradigm that I propose will truly advance human knowledge and enable us to change our way of being in the world. In order to liberate oneself from seeing the world in a particular way I use skillful means to unseat all the understandings that we have all been inculcated with. This can be destabilizing, and you might find yourself getting annoyed, or even frightened. To paraphrase a Buddhist proverb: Better not to start; but if started, better to finish: -/- Volume 2. The Way of Contemplation — In this volume, the paradigm of Responsive Naturing is developed, building upon the dialogs in volume 1. This volume challenges the reader, since breaking free of one’s existing cognitive frame and paradigmatic understanding is not a trivial exercise, and neither is restructuring one’s thoughts to fit into a new paradigm. This section explains what Responsive Naturing means, how it works in both spiritual and scientific senses, my specific arguments for why it is the answer to our need for a better way to account for phenomena and experience, and how our way of being in the world can change because of it. I attempt to show, via a myriad of independent fields of study, just how powerful this paradigm is in explaining the various phenomena that until now, either had no scientific explanation, or had an incoherent and never proven one. -/- Volume 3. The Way of Tradition — This volume provides the reader with traditional descriptions of similar types of meditation to that which I am presenting. These techniques are related by the unusual support for meditation that they use: that of Inner Spontaneous Sound. This information is provided for two reasons: 1) to validate the technique I present in volume 4, The Way of Meditation, by showing the high esteem that these techniques have been held in by all spiritual traditions, and 2) to present a rational explanation for the technique’s effectiveness, based upon responsive naturing. Volume 4. The Way of Meditation — This volume describes the practice that I call “Great Responsiveness Meditation” which will allow the reader to: 1) engage in a long-term meditative and contemplative practice in order to attain the insights that are the foundation for the novel paradigm that I am presenting; and 2) to benefit from two unique side-effects of using inner spontaneous sound: one which protects the meditator during traumatic and extreme emotional experiences, especially of the kind now expected because of the current global environmental and societal crises; and the other — which is widely attested to — is an alchemical-like change in the meditator, who quickly displays compassion without self-centered concern. In Buddhism, this is known by the Sanskrit word “Mahākaruṇā,” which is the type of responsive compassion displayed by all enlightened beings. It is a permanent change in how we live our life, and it enables each of us to overcome our worst inculcated selfish behaviors. 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The central motivating idea behind the development of this work is the concept of prespace, a hypothetical structure that is postulated by some physicists to underlie the fabric of space or space-time. I consider how such a structure could relate to space and space-time, and the rest of reality as we know it, and the implications of the existence of this structure for quantum theory. Understanding how this structure could relate to space and to the rest of reality requires, (...) I believe, that we consider how space itself relates to reality, and how other so-called "spaces" used in physics relate to reality. In chapter 2, I compare space and space-time to other spaces used in physics, such as configuration space, phase space and Hilbert space. I support what is known as the "property view" of space, opposing both the traditional views of space and space-time, substantivalism and relationism. I argue that all these spaces are property spaces. After examining the relationships of these spaces to causality, I argue that configuration space has, due to its role in quantum mechanics, a special status in the microscopic world similar to the status of position space in the macroscopic world. In chapter 3, prespace itself is considered. One way of approaching this structure is through the comparison of the prespace structure with a computational system, in particular to a cellular automaton, in which space or space-time and all other physical quantities are broken down into discrete units. I suggest that one way open for a prespace metaphysics can be found if physics is made fully discrete in this way. I suggest as a heuristic principle that the physical laws of our world are such that the computational cost of implementing those laws on an arbitrary computational system is minimized, adapting a heuristic principle of this type proposed by Feynman. In chapter 4, some of the ideas of the previous chapters are applied in an examination of the physics and metaphysics of quantum theory. I first discuss the "measurement problem" of quantum mechanics: this problem and its proposed solution are the primary subjects of chapter 4. It turns out that considering how quantum theory could be made fully discrete leads naturally to a suggestion of how standard linear quantum mechanics could be modified to give rise to a solution to the measurement problem. The computational heuristic principle reinforces the same solution. I call the modified quantum mechanics Critical Complexity Quantum Mechanics (CCQM). I compare CCQM with some of the other proposed solutions to the measurement problem, in particular the spontaneous localization model of Ghirardi, Rimini and Weber. Finally, in chapters 5 and 6, I argue that the measure of complexity of quantum mechanical states I introduce in CCQM also provides a new definition of entropy for quantum mechanics, and suggests a solution to the problem of providing an objective foundation for statistical mechanics, thermodynamics, and the arrow of time. (shrink)

This paper argues for a metaphysics of relations based on a characterization of quantum entanglement in terms of non-separability, thereby regarding entanglement as a sort of holism. By contrast to a radical metaphysics of relations, the position set out in this paper recognizes things that stand in the relations, but claims that, as far as the relations are concerned, there is no need for these things to have qualitative intrinsic properties underlying the relations. This position thus opposes a metaphysics (...) of individual things that are characterized by intrinsic properties. A principal problem of the latter position is that it seems that we cannot gain any knowledge of these properties insofar as they are intrinsic. Against this background, the rationale behind a metaphysics of relations is to avoid a gap between epistemology and metaphysics. (shrink)

We propose a model of physics that blends Rovelli’s relational quantum mechanics (RQM) interpretation with the language of finite information quantities (FIQs), defined by Gisin and Del Santo in the spirit of intuitionistic mathematics. We discuss deficiencies of using real numbers to model physical systems in general, and particularly under the RQM interpretation. With this motivation for an alternative mathematical language, we propose the use of FIQs to model the world under the RQM interpretation, wherein we view the (...) propensities that make up a FIQ as quantifications of potential interaction. Under this model, the stable facts, relative facts, and shifting perspectives that make up the relational interpretation correspond to shifting digits and propensities of the FIQs. The model’s predictions agree with those of both classical and quantum physics, and it is indeterministic. We also propose explanations, with examples, for how the propensities of a FIQ are distributed, and how its digits become actualized. This is equivalent to the notion of the measurement problem, and the question of what causes wave function collapse. In short, by stepping through the “new door” opened by the language of FIQs, we attempt to describe the world under the relational interpretation. (shrink)

Scientific perspectivism, or perspectival realism, is a view according to which scientific knowledge is neither utterly objective nor independent of the world “as it is”, but always tied to some particular ways of conceptualization and interaction with Nature. In the present paper, I employ Robert Rosen’s concept of the modeling relation for arguing that there are two basic reasons why our knowledge of natural systems is perspectival in this sense. The first of these pertains to the dualism between a system (...) and its environment, which is necessarily imposed by a scientist focusing on the former. The second pertains to the complexity of complex systems; a complex system understood as a system in which different kinds of causal entailments intertwine together. As I discuss in the paper besides developing the argument, perspectivism thus understood ties together several issues ranging from organicism to emergentism and to processual philosophy, and from the ceteris paribus talk of biology to the measurement problem of quantum mechanics. I also discuss Rosen’s relational formalisms as a concrete example of how perspectival epistemology might directly suggest novel strategies and practices of doing theoretical science. (shrink)

Symmetry-based explanations using symmetry breaking as the key explanatory tool have complemented and replaced traditional causal explanations in various domains of physics. The process of spontaneous SB is now a mainstay of contemporary explanatory accounts of large chunks of condensed-matter physics, quantum field theory, nonlinear dynamics, cosmology, and other disciplines. A wide range of empirical research into various phenomena related to symmetries and SB across biological scales has accumulated as well. Led by these results, we identify and explain some (...) common features of the emergence, propagation, and cascading of SB-induced layers across the biosphere. These features are predicated on the thermodynamic openness and intrinsic functional incompleteness of the systems at stake and have not been systematically analyzed from a general philosophical and methodological perspective. We also consider possible continuity of SB across the physical and biological world and discuss the connection between Darwinism and SB-based analysis of the biosphere and its history. (shrink)

A novel conceptual framework is introduced for the Complexity Levels Theory in a Categorical Ontology of Space and Time. This conceptual and formal construction is intended for ontological studies of Emergent Biosystems, Super-complex Dynamics, Evolution and Human Consciousness. A claim is defended concerning the universal representation of an item’s essence in categorical terms. As an essential example, relational structures of living organisms are well represented by applying the important categorical concept of natural transformations to biomolecular reactions and relational (...) structures that emerge from the latter in living systems. Thus, several relational theories of living systems can be represented by natural transformations of organismic, relational structures. The ascent of man and other living organisms through adaptation, is viewed in novel categorical terms, such as variable biogroupoid representations of evolving species. Such precise but flexible evolutionary concepts will allow the further development of the unifying theme of local-to-global approaches to highly complex systems in order to represent novel patterns of relations that emerge in super- and ultra-complex systems in terms of compositions of local procedures. Solutions to such local-to-global problems in highly complex systems with ‘broken symmetry’ might be possible to be reached with the help of higher homotopy theorems in algebraic topology such as the generalized van Kampen theorems (HHvKT). Categories of many-valued, Łukasiewicz-Moisil (LM) logic algebras provide useful concepts for representing the intrinsic dynamic ‘asymmetry’ of genetic networks in organismic development and evolution, as well as to derive novel results for (non-commutative) Quantum Logics. Furthermore, as recently pointed out by Baianu and Poli (Theory and applications of ontology, vol 1. Springer, Berlin, in press), LM-logic algebras may also provide the appropriate framework for future developments of the ontological theory of levels with its complex/entangled/intertwined ramifications in psychology, sociology and ecology. As shown in the preceding two papers in this issue, a paradigm shift towards non-commutative, or non-Abelian, theories of highly complex dynamics—which is presently unfolding in physics, mathematics, life and cognitive sciences—may be implemented through realizations of higher dimensional algebras in neurosciences and psychology, as well as in human genomics, bioinformatics and interactomics. (shrink)

The subjective Bayesian interpretation of quantum mechanics and Rovelli’s relational interpretation of quantum mechanics are both notable for embracing the radical idea that measurement outcomes correspond to events whose occurrence is relative to an observer. Here we provide a detailed study of their similarities and especially their differences.

Recent developments regarding the pharmacology of psychoactive substances are significant for treating depressions or opioid addictions. Current theories, hypotheses, and models of drug effects assume a cause–effect narrative, which is based on a stimulus/response mechanism. These narratives prioritize effects rather than conscious experiences. In this sense, drug experiences are quickly subsumed into common categories and codes of biological determinism. If subjective experiences are in the focus of the research, it quickly becomes a link to mystical, spiritual, or transcendental narratives. These (...) classifications lead to epistemological doublets (Gadamer). In this article, psychedelic experiences of drug users are analyzed in the frame of the pharmaco-analysis by Deleuze/Guattari. These framed psychedelic experiences are interpreted by means of a non-philosophical approach through philo-fictions (Laruelle), i.e., contradictory assumptions and hyperspeculations. In this respect, the aim of this article is to bring philo-fictions in relation to psychedelic experiences and to discuss them with models of information science, quantum mechanics, new materialism, and the philosophy of immanence. The result will be an open synthesis, with the assumption of further reflections on the agency, immanence, and the wholeness of matter. (shrink)

It is proposed that a human conscious experience of the sort we report to each other reflects a direct causal interaction between a pattern of information about the world, encoded in a field of postsynaptic potentials, and a quantized mode of excitation occupying dendritic cytoskeleton. The requirement for a quantized account is seen simply as the need for an event of experience to be a single indivisible, but richly patterned, causal relation between information and an 'informee'. It is argued that (...) the informee is likely to be a higher-order quantized collective mode (much as proposed by Craddock and colleagues, 2017) with the biologically relevant dynamics likely also to be describable in classical terms. No specific interpretation of quantum theory is needed. In this scenario, anaesthetics would abrogate reportable experience by detuning parameters underpinning cytoskeletal informee modes, perhaps critically increasing associated impedence. It is also proposed that tuning and detuning of informee modes in individual dendritic trees by binding of accessory proteins to cytoskeleton plays a physiological role in short-term memory and truth evaluation through ascertainment of sequential signal pattern consonance. Components of this model may be involved in cellular adaptive responses in many types of organism. (shrink)

It has been tacitly assumed that certain fundamental “laws” of science have the same meaning and significance in the different scientific disciplines. Outside of quantum physics the law of causality was regarded as such a concept which was most generally applicable in the description of the systems of nature. However, the role of causality in recent research in biology seems not quite clear. There an explanation of the specific properties of biological systems does not assume the form of (...) a simple law such as a mathematical expression relating different states of one and the same system. Rather it is attempted to show how the properties of the system as a whole are established by the specific interaction of the parts of the system. (shrink)

This paper argues for a metaphysics of relations based on a characterization of quantum entanglement in terms of non-separability, thereby regarding entanglement as a sort of holism. By contrast to a radical metaphysics of relations, the position set out in this paper recognizes things that stand in the relations, but claims that, as far as the relations are concerned, there is no need for these things to have qualitative intrinsic properties underlying the relations. This position thus opposes a metaphysics (...) of individual things that are characterized by intrinsic properties. A principal problem of the latter position is that it seems that we cannot gain any knowledge of these properties insofar as they are intrinsic. Against this background, the rationale behind a metaphysics of relations is to avoid a gap between epistemology and metaphysics. (shrink)

There exist several phenomena breaking the classical probability laws. The systems related to such phenomena are context-dependent, so that they are adaptive to other systems. In this paper, we present a new mathematical formalism to compute the joint probability distribution for two event-systems by using concepts of the adaptive dynamics and quantum information theory, e.g., quantum channels and liftings. In physics the basic example of the context-dependent phenomena is the famous double-slit experiment. Recently similar examples have been found (...) in biological and psychological sciences. Our approach is an extension of traditional quantum probability theory, and it is general enough to describe aforementioned contextual phenomena outside of quantum physics. (shrink)

The measurement problem of quantum theory is discussed, and the difficulty of trying to solve it within the confines of a local, Lorentz-invariant physics is emphasised. This leads to the obvious suggestion to seek a solution beyond physics, in particular, by introducing the concept of consciousness. The resulting dualistic model, in the natural form suggested by quantum theory, is shown to differ in several respects from the classical model of Descartes, and to suggest solutions to some of the (...) long-standing problems concerning the relation of consciousness to the physical world. (shrink)

The most majestic scientific achievement, of this century in mathematical beauty, axiomatic consistency, and experimental verifications has been special relativity with its unitary structure at the operator level, and canonical structure at the classical levels, which has turned out to be exactly valid for point particles moving in the homogenenous and isotropic vacuum (exterior dynamical problems). In recent decades a number of authors have studied nonunitary and noncanonical theories, here generally calleddeformations for the representation of broader conditions, such as extended (...) and deformable particles moving within inhomogeneous and anisotrophic physical media (interior dynamical problems). In this paper we show that nonunitary deformations, including, q-, k-, quatum-, Lie-isotopic, Lie-admissible, and other deformations, even thoughmathematically correct, have a number of problematic aspects ofphysical character when formulated on conventional spaces over conditional fields, such as lack of invariance of the basic space-time units, ambiguous applicability to measurements, loss of Hermiticity-observability in time, lack of invariant numerical predictions, loss of the axions of special relativity, and others. We then show that the classical noncanonical counterparts of the above nonunitary deformations are equally afflicted by corresponding problems of physical consistency. We also show that the contemporary formulation of gravity is afflicted by similar problematic aspects because Riemannian spaces are noncanonical deformations of Minkowskian spaces, thus having noninvariant space-time units. We then point out that new mathematical methods, calledisotopies, genotopies, hyperstructures and their isoduals, offer the possibilities of constructing a nonunitary theory, known asrelativistic hadronic mechanics which: (1) is as axiomatically consistent as relativistic quantum mechanics, (2) preserves the abstract axioms of special relativity, and (3) results in a completion of the conventional mechanics much along the celebrated Einstein-Podolski-Rosen argument. A number of novel applications are indicated, such as a geometric unification of the special and general relativity via the isominkowskian geometry in which the two relativities are differentiated via the invariant basic unit, while preserving conventional Riemannian metrics, Einstein's field equations, and related experimental verifications; a novel operator form of gravity verifying the axioms of relativistic quantum mechanics under the universal isopoincaré symmetry; a new structure model of hadrons with conventional massive particles as physical constituents which is compatile with composite quarks and with established unitary classifications; and other novels applications in nuclear physics, astrophysics, theoretical biology, and other fields. The paper ends with the proposal of a number of new experiments, some of which may imply new practical applications, such as conceivable new forms of recycling nuclear waste. The achievement of axiomatic consistency in the study of the above physical problems has been possible for the first time in this paper thanks to mathematical advances that recently appeared in a special issue of theRendiconti Circolo Matematico Palermo, and in other journals identified in the Acknowledgements. (shrink)

The article analyzes the effectiveness of quantum theories of mental experience in relation to two ontological problems - the problem of the existence of consciousness in the material world and the problem of the interaction of consciousness and body. A critical analysis of the quantum theories of consciousness by Penrose-Hameroff, M. Tegmark, G. Stapp, M. Fischer and M.B. Mensky shows that they fail to fully explain how complex physical systems generate mental experience without violating the principle of causal (...) closure of the physical world and the principle of epistemological completeness of physics. Quantum mechanics provides specific processes that are the physical basis of the psyche, but do not explain the phenomenal aspect of subjective reality. Nevertheless, the Heisenberg uncertainty principle gives an understanding of how the interaction of consciousness and body within the scientific picture of the world can be carried out without violating the law of energy conservation. It is shown that the quantum theories of consciousness currently being developed have a predominantly panprotopsychic character, which faces a problem due to the fact that the protomental property of physical systems must be expressed quantitatively and correspond to the value included in the physical equations. As a result, it is concluded that in order to develop quantum theories of consciousness more effectively, it is necessary to give an emergent character, not jumping from the quantum level to the psychic, but explaining the mechanism of the emergence of systemic properties during the sequential transition between different ontological regions of existence, including physical, chemical, biological, neurophysiological and psychic. (shrink)