Whole genome sequencing and SNP genotyping arrays can paint strikingly different pictures of demographic history and natural selection. This is because genotyping arrays contain biased sets of pre‐ascertained SNPs. In this short review, we use comparisons between high‐coverage whole genome sequences of African hunter‐gatherers and data from genotyping arrays to highlight how SNP ascertainment bias distorts population genetic inferences. Sample sizes and the populations in which SNPs are discovered affect the characteristics of observed variants. We find that SNPs on genotyping (...) arrays tend to be older and present in multiple populations. In addition, genotyping arrays cause allele frequency distributions to be shifted towards intermediate frequency alleles, and estimates of linkage disequilibrium are modified. Since population genetic analyses depend on allele frequencies, it is imperative that researchers are aware of the effects of SNP ascertainment bias. With this in mind, we describe multiple ways to correct for SNP ascertainment bias. (shrink)

Since the very beginning, Confucianism has been troubled by a serious gap between its political ideals and the reality of societal circumstances. Contemporary Confucians must develop a viable method of governance that can retain the spirit of the Confucian ideal while tackling problems arising from nonideal modern situations. The best way to meet this challenge, Joseph Chan argues, is to adopt liberal democratic institutions that are shaped by the Confucian conception of the good rather than the liberal conception of (...) the right.Confucian Perfectionism examines and reconstructs both Confucian political thought and liberal democratic institutions, blending them to form a new Confucian political philosophy. Chan decouples liberal democratic institutions from their popular liberal philosophical foundations in fundamental moral rights, such as popular sovereignty, political equality, and individual sovereignty. Instead, he grounds them on Confucian principles and redefines their roles and functions, thus mixing Confucianism with liberal democratic institutions in a way that strengthens both. Then he explores the implications of this new yet traditional political philosophy for fundamental issues in modern politics, including authority, democracy, human rights, civil liberties, and social justice.Confucian Perfectionism critically reconfigures the Confucian political philosophy of the classical period for the contemporary era. (shrink)

This book critically assesses arguments for the existence of the God of classical theism, develops an innovative account of objects’ persistence, and defends new arguments against classical theism. The authors engage the following classical theistic proofs: Aquinas’s First Way, Aquinas’s De Ente argument, and Feser’s Aristotelian, Neo-Platonic, Augustinian, Thomistic, and Rationalist proofs. The authors also provide the first systematic treatment of the ‘existential inertia thesis’. By connecting the thesis to relativity theory and recent developments in the philosophy of physics, and (...) by developing a variety of novel existential-inertia-friendly explanations of persistence, they mount a formidable new case against classical theistic proofs. Finally, they defend new arguments against classical theism based on abstract objects and changing divine knowledge. The text appeals to students, researchers, and others interested in classical theistic proofs, the existence and nature of God, and the ultimate explanations of persistence, change, and contingency. (shrink)

"First published by Oxford University Press, 1916."--Title page verso.

In this book, Joseph Millum explains how parental rights and responsibilities are acquired, what they consist in, and how parents should go about making decisions on behalf of their children. In doing so, he provides a set of frameworks to help solve pressing ethical dilemmas relating to parents and children.

The thesis of the present volume is critical and dual. (1) Present day philosophy of man and sciences of man suffer from the Greek mis taken polarization of everything human into nature and convention which is (allegedly) good and evil, which is (allegedly) truth and fal sity, which is (allegedly) rationality and irrationality, to wit, the polar ization of all fields of inquiry, the natural and social sciences, as well as ethics and all technology, whether natural or social, into the (...) totally positive and the totally negative. (2) Almost all philosophy and sci ences of man share the erroneous work ethic which is the myth of man's evil nature - the myth of the beast in man, the doctrine of original sin. To mediate or to compromise between the first view of human nature as good with the second view of it as evil, sociologists have devised a modified utilitarianism with deferred gratification so called, and the theory of the evil of artificial competition (capitalist and socialist alike) and of keeping up with the Joneses. Now, the mediation is not necessary. For, the polarization makes for abstract errors which are simplistic views of rationality, such as reductionism and positivism of all sorts, as well as for concrete errors, such as the disposition to condemn repeatedly those human weaknesses which are inevitable, namely man's inability to be perfectly rational, avoid all error, etc. , thus setting man against himself as all too wicked. (shrink)

CONTEMPORARY ISSUES IN BUSINESS ETHICS, 6E introduces readers to business ethics by focusing on the influence of market mechanisms and social values on workplace norms. And because business is increasingly a global enterprise, this edition emphasizes the role of ethics both at home and abroad.

(1968 [1922]). It amounts to the claim that social phenomena must be explained by showing how they result from individual actions, which in turn must be explained through reference to the intentional states that motivate the individual actors. It involves, in other words, a commitment to the primacy of what Talcott Parsons would later call “the action frame of reference” (Parsons 1937: 43-51) in social-scientific explanation. It is also sometimes described as the claim that explanations of “macro” social phenomena must (...) be supplied with “micro” foundations, ones that specify an action-theoretic mechanism (Alexander, 1987). (shrink)

ABSTRACT I begin by developing a challenge for the Higher-Order Thought variant of Higher-Order representational theories of consciousness. The challenge is to account for the distinctive phenomenal character of visual experience—its presentational character. After setting out the challenge, I articulate a novel form of Higher-Order theory that can account for presentational character—the Map Theory of consciousness. The theory’s distinctive claim is that the relevant higher-order representations have a cartographic format.

This essay takes issue with Alasdair MacIntyre’s denial that teaching is a practice. It does so less by appeal to MacIntyre’s concept of practice than by criticism of his conception of teaching. It argues that this conception, as reconstructed from adversions to teaching in a range of his writings, does less than justice to what good teachers accomplish; and that, if this inadequacy is rectified—as much else in his writings suggests that it ought to be—there are clearer grounds for acknowledging (...) teaching as a practice. (shrink)

In this paper, I argue that there is an inconsistency between two presentist doctrines: that of ontological symmetry and asymmetry of fixity. The former refers to the presentist belief that the past and future are equally unreal. The latter refers to the A-Theoretic intuition that the past is closed or actual, and the future is open or potential. My position in this paper is that the presentist is unable to account for the temporal asymmetry that is so fundamentally a part (...) of her theory. In Section I, I briefly outline a recent defence of presentism due to Craig, and argue that a flaw in this defence highlights the tension between the presentist's doctrines of ontological symmetry and asymmetry of fixity. In Section II, I undertake an investigation, on the presentist's behalf, in order to determine whether she is capable of reconciling these two doctrines. In the course of the investigation, I consider different asymmetries, other than that of ontology, which might be said fundamentally to constitute temporal asymmetry, and the asymmetry of fixity in particular. In Section III, I also consider whether the presentist is able to avail herself of some of the standard B-Theoretic accounts of the asymmetry of fixity, and argue that she cannot. Finally, I conclude that temporal asymmetry cannot be accounted for (or explained) other than through the postulation of an ontological asymmetry. (shrink)

Medical ethics has become an important and recognized component of physician training. There is one area, however, in which medical students receive little guidance. There is practically no discussion of the financial aspects of medical practice. My objective in this paper is to initiate a discussion about the moral dimension of physician billing practices. I argue that physicians should expand their conception of professional responsibility in order to recognize that their moral obligations toward patients include a commitment to honest and (...) forthright billing practices. I argue that physicians should aspire to a standard of clinical accuracy—not legal adequacy—in describing their activities. More generally, physicians should strive to promote an integrity-based professional culture, first and foremost by stigmatizing rather than celebrating creative billing practices, as well as condemning the misguided sense of solidarity that currently makes it taboo for physicians to criticize each other on this score. (shrink)

_If you were free in doing something and morally responsible for it, you could have done otherwise. That_ _has seemed a pretty firm proposition among the old, new, clear, unclear and other propositions in the_ _philosophical discussion of freedom and determinism. If you were free in what you did, there was an_ _alternative. It is also at least natural to think that if determinism is true, you can never do otherwise than_ _you do. G. E. Moore, that Cambridge reasoner in (...) whose shadow Wittgenstein ought to be standing,_ _considered the matter. He pointed out that even if determinism is true, there remains a sense in which you_ _can still do otherwise than you do: you will do otherwise if you so choose. That, on reflection, is consistent_ _with determinism. The doctrine of the compatibility of freedom and determinism is saved. Joseph Keim_ _Campbell, strong philosopher at Washington State University, provides the latest thinking on this seemingly_ _unavoidable dispute. You do not have to agree that either compatibilism or incompatibilism must be true in_ _order to appreciate the carefulness of his reasoning in this piece of ongoing American philosophy. It_ _requires and repays attention._. (shrink)

This paper seeks to give an account of what it is for an individual to instantiate thisness (i.e. primitive individual essence). Thisnesses are peculiar entities, and even those who endorse their existence and instantiation by objects/entities, have said very little about how an individual and its thisness are related. My approach will be to seek out a model for the instantiation of thisness by canvassing broadly Aristotelian accounts of the substance/attribute relation, and then by making appropriate modifications to the most (...) likely candidates in order to accommodate an individual's instantiation of thisness. What will emerge is that the model with the most utility makes thisness redundant in the case of material substances. Nonetheless, I will suggest that a version of the model can be appropriately applied in the case of other individuals which might instantiate thisness: for example, events (where these are conceived as a fundamental category of ontology distinct from material substances). (shrink)

Two popular theses central to recent theorizing about consciousness are the transitivity principle and the transparency of experience. According to the former, conscious mental states are mental states we are aware of in some way. According to the latter, there is some awareness-relation that we seemingly cannot bear to our experiences. I argue that, within certain reasonable constraints, there is no precisification of these theses that renders them compatible.

This volume collects new, previously unpublished articles on Kaplan, analyzing a broad spectrum of topics ranging from cutting edge linguistics and the ...

There is a need for empirically based research on social and ethical challenges related to informed consent processes, particularly in studies focusing on adolescent sexual and reproductive health. In a pilot study of a school-based pregnancy prevention intervention in rural Zambia, the majority of the guardians who were asked to consent to their daughters’ participation, refused. In this paper we explore the reasons behind the low participation in the pilot with particular attention to challenges related to the community engagement and (...) informed consent process. The pilot was implemented in two schools and examined the acceptability of a package of interventions including economic support to families to keep their girls in school, pocket money for girls, youth club meetings on reproductive health, and community meetings to sensitize the community. Focus group discussions were conducted with girls who participated in the pilot, boys in their class and with parents. Individual semi-structured interviews were conducted with teachers, peer educators and community health workers involved in the coordination of the intervention as well as with religious and traditional leaders. Data were analyzed through thematic analysis. The findings indicate that inadequate use of recognized community communication channels during the community engagement process and dissemination of information about the pilot resulted in limited understanding of the pilot concept by the community. This surfaced through uncertainty and fear that the intervention may result in loss of control over daughters, worries about why money was provided unconditionally to girls, and suspicion of links to satanism. The sense of insecurity appeared to be exacerbated by low literacy levels, poverty, fear of loss of bride wealth, perceived disregard for local perceptions of social status, and scanty trust in the actors implementing the pilot. Inadequate use of locally appropriate channels in the dissemination of information created room for interpretation and facilitated development of mistrust, undermining the conditions for community engagement and actual informed consent. A key lesson learnt is the importance of taking seriously the complexity of local values and structures that may impact people’s capability to consent or not consent to a study in an informed manner. (shrink)

Most causal discovery algorithms in the literature exploit an assumption usually referred to as the Causal Faithfulness or Stability Condition. In this paper, we highlight two components of the condition used in constraint-based algorithms, which we call “Adjacency-Faithfulness” and “Orientation- Faithfulness.” We point out that assuming Adjacency-Faithfulness is true, it is possible to test the validity of Orientation- Faithfulness. Motivated by this observation, we explore the consequence of making only the Adjacency-Faithfulness assumption. We show that the familiar PC algorithm has (...) to be modified to be correct under the weaker, Adjacency-Faithfulness assumption. The modified algorithm, called Conservative PC (CPC), checks whether Orientation- Faithfulness holds in the orientation phase, and if not, avoids drawing certain causal conclusions the PC algorithm would draw. Howtion: ever, if the stronger, standard causal Faith-. (shrink)

Gabriele Contessa has recently introduced and defended a view he calls ‘non-eliminative nihilism’. Non-eliminative nihilism is the conjunction of mereological nihilism and non-eliminativism about ordinary objects. Mereological nihilism is the thesis that composite objects do not exist, where something is a composite object just in case it has proper parts. Eliminativism about ordinary objects denies that ordinary objects exist. Eliminativism thus implies, for example, that there are no galaxies, planets, stars, ships, tables, books, organisms, cells, molecules, or atoms. Non-eliminativism is (...) the denial of eliminativism. Thus, NEN is the intriguing thesis that although composite objects do not exist, ordinary objects do. In this essay, I, first, summarize Contessa’s core support for NEN. Second, I describe two flaws in that support when it comes to organismic terms. Third, I consider and reject two possible responses on behalf of NEN’s defenders. Fourth, I show how the flaws cast doubt upon NEN itself. Finally, I offer reasons to think that if nihilism is true, then the folk have probably been trying to fix the reference of organismic terms to apparent objects within illusions. (shrink)

Presupposing that all knowledge is the study of a unitary order of nature, the author maintains that the study of literature should be included within the larger field of evolutionary theory. He outlines four elementary concepts in evolutionary theory, and he argues that these concepts should regulate our understanding of literature. On the basis of these concepts, he repudiates the antirealist and irrationalist views that, under the aegis of “poststructuralism,” have dominated academic literary studies for the past two decades. He (...) examines the linkage between poststructuralism and standard social science, and he speculates about the ideological and disciplinary motives that have hitherto impeded evolutionary study in both the social sciences and the humanities. Finally, he distinguishes literature from science and argues that literary criticism integrates elements of both. (shrink)

This study investigates factors impacting perceptions of ethical conduct of peers of 293 students in four US universities. Self-reported ethical behavior and recognition of emotions in others (a dimension of emotional intelligence) impacted perception of ethical behavior of peers. None of the other dimensions of emotional intelligence were significant. Age, Race, Sex, GPA, or type of major (business versus nonbusiness) did not impact perception of ethical behavior of peers. Implications of the results of the study for business schools and industry (...) professionals are discussed. (shrink)

ספר ויקרא, או תורת כוהנים, נראה היום פחות מעניין מאשר ספרי-קודש אחרים, כי הוא ספר מצוות - הוא כולל כארבעים אחוז מכל תרי"ג המצוות - ואף במידה רבה מצוות שאינן בתוקף מאז חורבן בית-המקדש. אך יש בו עניין, שכן הוא מוכר כספר השלם ביותר מבחינת סגנונו ותכנו, ואולי אף בכך שעריכתו כנראה עתיקה ביותר - לא לדעת דון יצחק אברבנאל, שכן הוא לא הטיל בספק כי תורה נתנה למשה מפי הגבורה - אמנם לא בסיני אך בכל-זאת למשה מפי הגבורה. החוקרים (...) המתעלמים מדעה זו.. (shrink)

Donald Davidson's work has been of seminal importance in the development of analytic philosophy and his views on the nature of language, mind and action remain the starting point for many of the central debates in the analytic tradition. His ideas, however, are complex, often technical, and interconnected in ways that can make them difficult to understand. This introduction to Davidson's philosophy examines the full range of his writings to provide a clear succinct overview of his ideas. This book begins (...) with an account of the assumptions and structure of Davidson's philosophy of language, introducing his compositionalism, extensionalism and commitment to a Tarski-style theory of truth as the model for theories of meaning. It goes on to show how that philosophical framework is to be applied and how it challenges the traditional picture. Marc Joseph examines Davidson's influential work on action theory and events and discusses the commonly made charge that his theory of action and mind leaves the mental as a mere 'epiphenomenon' of the physical. The final section explores Davidson's philosophy of mind, some of its consequences for traditional views of subjectivity and objectivity and, more generally, the relation between minded beings and the physical and mental world they occupy. (shrink)

The debate concerning the role of intuitions in philosophy has been characterized by a fundamental disagreement between two main camps. The first, the autonomists, hold that, due to the use in philosophical investigation of appeals to intuition, most of the central questions of philosophy can in principle be answered by philosophical investigation and argument without relying on the sciences. The second, the naturalists, deny the possibility of a priori knowledge and are skeptical of the role of intuition in providing evidence (...) in philosophical inquiry. In spite of the seemingly stark and deep disagreement between the autonomist and the naturalist, in this paper I will attempt to suggest that there is a way to mount a partial defense of intuition-based philosophical practice on naturalist grounds. As will be seen, doing so will require a number of concessions that will satisfy few autonomists while simultaneously disappointing those naturalists who might have thought that all notions of the a priori had been successfully laid to rest. However, I will argue that the account proposed here will preserve those features of traditional philosophical practice that matter most and better explain the history of successes and failures of that practice, thus answering the worries of the autonomist, and that the rejection of the No A Priori Thesis attendant with the account presented here is indeed demanded by the current theories of our best scientific understanding of the mind, thus pacifying the rabid naturalistic critic of any version of apriorism. (shrink)

This paper examines the need for static dispositions within the basic ontology of the powers view of properties. To lend some focus, Neil Williams’s well developed case for static dispositions is considered. While his arguments are not necessarily intended to address fundamental ontology, they still provide a useful starting point, a springboard for diving into the deeper metaphysical waters of the dispositionalist approach. Within that ontological context, this paper contends that Williams’s arguments fail to establish the need to posit static (...) dispositions, or at least any sort not already well appreciated by advocates of the powers view. The paper then proceeds to suggest an alternative motivation for positing static dispositions, the success of which depends greatly on which ontological approach to objects is paired with the powers view. (shrink)

A person incurs inchoate criminal liability when he incites another person or other persons to commit a crime. The most salient characteristic of incitement, in comparison with the other forms of inchoate crime, is the existence of a communication that is made with a view to persuading the addressee to commit an offence. This article explores the question of why incitement should incur criminal liability, and the nature of such liability. It also identifies its distinctive features. The principal focus here (...) is on ambiguity in the putative words of incitement and on questions of gauging whether the words have had any effect on the actions of the addressee. It covers both the standard criminal offences and conduct which, arguably, should not be regulated by the criminal law, thereby raising issues of freedom of speech. Legal issues are set in the context of the common law generally, while drawing on English law in matters of detail. (shrink)

In the first comprehensive biography of Ferdinand de Saussure, John E. Joseph restores the full character and history of a man who is considered the founder of modern linguistics and whose ideas have influenced literary theory, philosophy, cultural studies, and virtually every other branch of humanities and the social sciences.

Excerpt from Scepsis Scientifica: Or, Confest Ignorance, the Way to Science; In an Essay of the Vanity of Dogmatizing, and Confident Opinion He seems to have been brought up, if not as an extreme sectary, at least in some school of Puritanism which allowed small scope for independent judgment. Thus he tells us, in his "Plus Ultra" (p. 142): "In my first education I was continually instructed into a religious and fast adherence to everything I was taught, and a dread (...) of disputing in the least article," - a mode of education which he was wont in after life vehemently to denounce. He entered the University of Oxford in 1652, and took his degree three years after. In the dearth of more direct information, his love of culture and mental independence may fairly be inferred from his associates. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

In “Is semantics possible?” Putnam connected two themes: the very possibility of semantics (as opposed to formal model theory) for natural languages and the proper semantic treatment of common nouns. Putnam observed that abstract semantic accounts are modeled on formal languages model theory: the substantial contribution is rules for logical connectives (given outside the models), whereas the lexicon (individual constants and predicates) is treated merely schematically by the models. This schematic treatment may be all that is needed for an account (...) of validity in a formal setting, but it does not help to understand how proper and common nouns function in reality (not in models). Putnam then initiated the empirical study of such nouns to indicate, (i), that the popular Frege-Carnap account of them as (“disguised” compound) predicates is empirically incorrect, and, (ii), that they offer a new paradigm for a naturalistic semantics of natural languages. We take Putnam’s program a couple of steps further. First, we investigate the semantics of common nouns and argue that they refer (to kinds), rather than apply by satisfaction/truth to a designation/denotation. Second, we point to general results about semantics as a theory whose fulcrum is the reference relation rather than satisfaction in models and validity across them. (shrink)

While denying that God has moral obligations, William Alston defends divine moral goodness based on God’s performance of supererogatory acts. The present article argues that an agent without obligations cannot perform supererogatory acts. Hence, divine moral goodness cannot be established on that basis. Defenses of divine moral obligation by Eleonore Stump and Nicholas Wolterstorff are also questioned. Against Stump, it is argued (among other things) that the temptations of Jesus do not establish the existence of a tendency to sin in (...) a divine being. Hence, Stump’s Christological objection to Alston’s denial of divine moral obligation fails. Some counterexamples to that denial offered by Wolterstorff also fail. It is concluded that claims of divine moral goodness remain problematic. (shrink)