The prospect of using cell-based interventions to treat neurological conditions raises several important ethical and policy questions. In this target article, we focus on issues related to the unique constellation of traits that characterize CBIs targeted at the central nervous system. In particular, there is at least a theoretical prospect that these cells will alter the recipients' cognition, mood, and behavior—brain functions that are central to our concept of the self. The potential for such changes, although perhaps remote, is cause (...) for concern and careful ethical analysis. Both to enable better informed consent in the future and as an end in itself, we argue that early human trials of CBIs for neurological conditions must monitor subjects for changes in cognition, mood, and behavior; further, we recommend concrete steps for that monitoring. Such steps will help better characterize the potential risks and benefits of CBIs as they are tested and potentially used for treatment. (shrink)

Objective: To review the principles and practice of the use of conscious sedation for IVF.Design: The pertinent literature was reviewed and recommendations are provided.Result(s): Conscious sedation appears to be the most commonly used method of pain relief for transvaginal retrieval of oocytes. Conscious sedation does not require the presence of an anesthesiologist and can be done in freestanding clinics. Agents commonly used include opioids in combination with benzodiazepines. This combination minimizes pain, decreases anxiety, and provides sedation and some amnesia Adjuvants (...) such as promethazine and hydroxyzine can also be used but often are not needed. Conscious sedation is well tolerated by patients and does not require highly specialized equipment. However, there are specific safeguards that should be followed. Only a few toxicity studies have been performed, but they are reassuring because they have not found significant effects on fertilization or cleavage.Conclusion(s): Conscious sedation appears to be a safe and cost-effective method of providing analgesia and anesthesia for transvaginal retrieval of oocytes. (shrink)

Andrei A. Buckareff is Assistant Professor at Marist College, USA --.

table ronde du Centre national de la recherche scientifique, Paris, 27-29 mars 1979. Huygens et la France (Paris, Vrin, 1981, p. 99-114) CHRISTIAAN HUYGENS VU PAR LEIBNIZ par Albert HEINEKAMP (*) (Leibniz-Archiv, Hannover) Les ...

The author re-Examines the evidence (including the manuscript evidence) relevant to an understanding of the historico-Philosophical relationship of john locke to rene descartes and, Consequently, Of the relationship of "the empirical school" to "rationalism." arguing against a standardly accepted view (that of, Among others, Richard aaron), He suggests that, Both early and late, In the drafts of 1671 and in the "mature" "essay", Locke rejected descartes' science and philosophy of science precisely because he rejected his epistemology; furthermore, He rejected descartes' (...) epistemology precisely because he rejected his method and logic. (shrink)

Richard Janko's acclaimed translation of Aristotle's _Poetics_ is accompanied by the most comprehensive commentary available in English that does not presume knowledge of the original Greek. Two other unique features are Janko's translations with notes of both the _Tractatus Coislinianus_, which is argued to be a summary of the lost second book of the Poetics, and fragments of Aristotle’s dialogue On Poets, including recently discovered texts about catharsis, which appear in English for the first time.

The Greenberger-Horne-Zeilinger state is the most famous example of a state with multiparticle entanglement. In this article we describe a group theoretic framework we have been developing for understanding the entanglement in general states of two or more quantum particles. As far as entanglement is concerned, two states of n spin-1/2 particles are equivalent if they are on the same orbit of the group of local rotations (U(2)n). We consider both pure and mixed states and calculate the number of independent (...) parameters needed to describe such states up to this equivalence. We describe how the entanglement of states in a given equivalence class may be characterized by the stability group of the action of the group of local rotations on any of the states in the class. We also show how to calculate invariants under the group of local actions for both pure and mixed states. In the case of mixed states we are able to explicitly exhibit sets of invariants which allow one to determine whether two generic mixed states are equivalent up to local unitary transformations. (shrink)

Politics and the Religious Imagination is the product of a group of interdisciplinary scholars each analyzing the connections between religious narratives and the construction of regional and global politics, combining a set of theoretical and philosophic insights with several case studies that represent varied geographies and religious customs. The past decade has seen increasing interest in the links between religion and politics, and this edited volume seeks to take religion seriously as a motivator of action. Few studies have attempted to (...) bring together the multi-disciplinary work in this burgeoning field of study and this work takes a global perspective, using a variety of contexts including East-West relations to analyze the following key themes: the constructive and destructive hermeneutics of religious stories the relevance and importance of religion as a dominant political narrative the rise of new stories among groups as agents of change the way that religious narratives help to define and constrain the Other the manipulation of religious stories for political benefit This work argues that it is insufficient to judge the relationship of religion and politics through mere institutional or quantitative lenses, and this collection proves that while this promise of the narrative part of the social imaginary has been recognized in political theory to a certain extent, its influence in the realm of empirical political science has yet to be fully considered. Combining the work of a wide range of experts, this collection will be of great interests to scholars of politics, philosophy, religious studies, and the literary influence of religion. (shrink)

A statement in contemporary terms of an Aristotelian approach to ethics, spiced with numerous illustrations from the modern arts and sciences. Veatch attempts to persuade the reader of the importance of the moral and intellectual virtues for leading an ethical life, and ends with a definition of the good "simply as the perfect with respect to the imperfect, the complete with respect to the incomplete, the actual with respect to the potential". He argues against ethical relativism and scepticism, Platonic "intellectualism", (...) Utilitarianism, the contemporary second-intentional linguistic approach, and certain aspects of existentialism.--A. S. H. (shrink)

jild-i 1. [Without special title] -- jild-i 2. Shāmil-i mustadrakāt va muṣṭalaḥāt va kullīyāt-i falsafah -- jild-i 3. Ilāhiyāt -- jildi 4. Ilāhiyāt bi-maʻnī-i akhaṣṣ -- jild-i 5. Dar Ilāhiyāt bi-maʻnī-i akhaṣṣ.

We present the idea of searching for X-rays as a signature of the mechanism inducing the spontaneous collapse of the wave function. Such a signal is predicted by the continuous spontaneous localization theories, which are solving the “measurement problem” by modifying the Schrödinger equation. We will show some encouraging preliminary results and discuss future plans and strategy.

Recent data indicate that under a specific posthypnotic suggestion to circumvent reading, highly suggestible subjects successfully eliminated the Stroop interference effect. The present study examined whether an optical explanation could account for this finding. Using cyclopentolate hydrochloride eye drops to pharmacologically prevent visual accommodation in all subjects, behavioral Stroop data were collected from six highly hypnotizables and six less suggestibles using an optical setup that guaranteed either sharply focused or blurred vision. The highly suggestibles performed the Stroop task when naturally (...) vigilant, under posthypnotic suggestion not to read, and while visually blurred; the less suggestibles ran naturally vigilant, while looking away, and while visually blurred. Although visual accommodation was precluded for all subjects, posthypnotic suggestion effectively eliminated Stroop interference and was comparable to looking away in controls. These data strengthen the view that Stroop interference is neither robust nor inevitable and support the hypothesis that posthypnotic suggestion may exert a top-down influence on neural processing. (shrink)