Empirical philosophers of science aim to base their philosophical theories on observations of scientific practice. But since there is far too much science to observe it all, how can we form and test hypotheses about science that are sufficiently rigorous and broad in scope, while avoiding the pitfalls of bias and subjectivity in our methods? Part of the answer, we claim, lies in the computational tools of the digital humanities, which allow us to analyze large volumes of scientific literature. Here (...) we advocate for the use of these methods by addressing a number of large-scale, justificatory concerns—specifically, about the epistemic value of journal articles as evidence for what happens elsewhere in science, and about the ability of DH tools to extract this evidence. Far from ignoring the gap between scientific literature and the rest of scientific practice, effective use of DH tools requires critical reflection about these relationships. (shrink)

Binding specificity is a centrally important concept in molecular biology, yet it has received little philosophical attention. Here I aim to remedy this by analyzing binding specificity as a causal property. I focus on the concept’s role in drug design, where it is highly prized and hence directly studied. From a causal perspective, understanding why binding specificity is a valuable property of drugs contributes to an understanding of causal selection—of how and why scientists distinguish between causes, not just causes from (...) noncauses. In particular, the specificity of drugs is precisely what underwrites their value as experimental interventions on biological processes. (shrink)

Shannon information is commonly assumed to be the wrong way in which to conceive of information in most biological contexts. Since the theory deals only in correlations between systems, the argument goes, it can apply to any and all causal interactions that affect a biological outcome. Since informational language is generally confined to only certain kinds of biological process, such as gene expression and hormone signalling, Shannon information is thought to be unable to account for this restriction. It is often (...) concluded that a richer, teleosemantic sense of information is needed. I argue against this view, and show that a coherent and sufficiently restrictive theory of biological information can be constructed with Shannon information at its core. This can be done by paying due attention some crucial distinctions: between information quantity and its fitness value, and between carrying information and having the function of doing so. From this I construct an account of how informational functions arise, and show that the “subject matter” of these functions can easily be seen as the natural information dealt with by Shannon’s theory. (shrink)

Bio-ontologies are digital frameworks for handling biological and biomedical data. They consist of theoretical entities and relations with explicitly defined logical structures and precise definitions, whose purpose is to provide a shared language for representing information to be distributed and integrated across diverse scientific contexts. It is tempting to view bio-ontologies as clear and formal expressions of a scientific community’s ontological commitments about their domain of inquiry, and to view their integration as tantamount to the metaphysical unification of science that (...) some philosophers have envisaged. However, I argue that the local, practical, social and technological factors that influence their design prevent us from straightforwardly reading metaphysical conclusions from them. I discuss these complications and suggest how they can be overcome, revealing more general lessons for the development of a well-founded scientific metaphysics. (shrink)

Jacques Monod (1971) argued that certain molecular processes rely critically on the property of chemical arbitrariness, which he claimed allows those processes to “transcend the laws of chemistry”. It seems natural, as some philosophers have done, to interpret this in modal terms: a biological relationship is chemically arbitrary if it is possible, within the constraints of chemical “law”, for that relationship to have been otherwise than it is. But while modality is certainly important for understanding chemical arbitrariness, understanding its biological (...) role also requires an account of the concrete causal-functional features that distinguish arbitrary from non-arbitrary phenomena. In this paper I elaborate on this under-emphasised aspect by offering a general account of these features: arbitrary relations are instantiated by mechanisms that involve molecular adapters, which causally couple two properties or processes which would otherwise be uncorrelated. Additionally, adapters work by acting as intermediate rather than cooperating causes. (shrink)

Numerous scholarly works focus solely on scientific metaphysics or biological practice, but few attempt to bridge the two subjects. This volume, the latest in the Minnesota Studies in the Philosophy of Science series, explores what a scientific metaphysics grounded in biological practices could look like and how it might impact the way we investigate the world around us. From Biological Practice to Scientific Metaphysics examines how to reconcile the methods of biological practice with the methods of metaphysical cosmology, notably regarding (...) the origins of life. The contributors take up a wide range of traditional metaphysics and philosophy of science topics, including natural kinds, medicine, ecology, genetics, scientific pluralism, reductionism, operationalism, mechanisms, the nature of information, and more. Many of the chapters represent the first philosophical treatments of significant biological practices. From causality and complexity to niche constructions and inference, the contributors review and discuss long-held objections to metaphysics by natural scientists. They illuminate how, in order to learn about the world as it truly is, we must look not only at what scientists say but also what they do: for ontology cannot be read directly from scientific claims. (shrink)

In “Trompe L'Oeil”, the seventh episode of Westworld, Bernard Lowe discovers the plans for his own body. Bernard's are ready‐made by someone else and uploaded into his brain, apparently unrelated to any real events. Bernard has memories of his son Charlie, which he thought referred to a real boy with whom he had a real relationship, and whose real death is the cause of his inescapable grief. Bernard might respond that lifelong grief is an excessive response to the death of (...) a fictional character. He realizes that the memories of that trauma have been fabricated by Robert Ford. Whether Charlie is a lie, a fiction, or a stranger, by grieving for him Bernard is sharing in a very human kind of experience. As malicious as Ford's motives were, maybe he was right about the need for a “cornerstone” of suffering to make Bernard human. (shrink)

Exploring what a scientific metaphysics grounded in biological practices could look like and how it might impact the way we investigate the world around us, the contributors to From Biological Practice to Scientific Metaphysics review and discuss long-held objections to metaphysics by natural scientists. They illuminate how, in order to learn about the world as it truly is, we must look not only at what scientists say but also what they do.

Can corporations remain socially responsible in today's fiercely competitive global economy? For several decades after World War II, companies like IBM, which exemplified what journalist Robert J. Samuelson called the 'good corporation,' poured forth material comforts and technological ideas while guaranteeing full employment and adequate retirement. In the 1980s all of that changed, as corporations moved to 'downsize' and become lean, mean global competitors. In this collection, thirteen prominent scholars in business ethics, finance, management, and religion and six corporate (...) leaders respond to a new essay by Samuelson that sounds the death knell of the 'good corporation.' They propose new approaches to corporate integrity and social responsibility in the global economy. The book will be useful in corporate workshops and will make an excellent business ethics text in philosophy departments and business schools. (shrink)

Salient landmarks enhance route learning. We hypothesised that semantically salient nostalgic landmarks would improve route learning compared to non-nostalgic landmarks. In two experiments, participants learned a route through a computer-generated maze using directional arrows and wall-mounted pictures. On the test trial, the arrows were removed, and participants completed the maze using only the pictures. In the nostalgia condition, pictures were of popular music artists and TV characters from 5 to 10 years ago. In the control condition, they were recent pictures (...) of these same artists and characters. In Experiment 1, in the test trial, participants in the nostalgia condition completed the maze faster than controls. Experiment 2 conceptually replicated these findings and extended them by exploring boundary conditions. Participants had to learn two mazes sequentially. In Maze 1, we placed nostalgic/control landmarks only at non-decision points (whereas we placed them at decision points in Experiment 1). In Maze 2, we placed nostalgic/control landmarks at decision points during acquisition but removed them in the test trial (whereas they were present in the test trial in Experiment 1). In both mazes, participants in the nostalgia (compared to control) condition completed the test trial faster. (shrink)

Der Artikel spürt den subtilen Veränderungen nach, die bei Patienten, die mit tiefer Hirnstimulation behandelt werden, möglicherweise beobachtet werden können. Dabei sollen im Rückgriff auf Konzeptionen zur narrativen Identität mittels einer möglichst genauen Beschreibung und Analyse der Selbstwahrnehmung der Patienten sowie der Wahrnehmung ihres Umfelds die Änderungen im praktischen Selbstverhältnis untersucht werden, u. a. am Beispiel technomorpher Metaphern, die von den Patienten in ihren Selbstbeschreibungen verwendet werden. Ziel ist es, die Neuartigkeit und das Spezifische der Neurotechnologien – über die bisherigen (...) Untersuchungen hinaus – hinsichtlich des Umgangs mit sich selbst herauszuarbeiten und greifbar zu machen. Abschließend werden auf Basis der Analyse der Patienten-Narrationen die entsprechenden normativen Implikationen für eine ethische Bewertung des Einsatzes von Neurotechnologien benannt. (shrink)

Der Artikel spürt den subtilen Veränderungen nach, die bei Patienten, die mit tiefer Hirnstimulation behandelt werden, möglicherweise beobachtet werden können. Dabei sollen im Rückgriff auf Konzeptionen zur narrativen Identität mittels einer möglichst genauen Beschreibung und Analyse der Selbstwahrnehmung der Patienten sowie der Wahrnehmung ihres Umfelds die Änderungen im praktischen Selbstverhältnis untersucht werden, u. a. am Beispiel technomorpher Metaphern, die von den Patienten in ihren Selbstbeschreibungen verwendet werden. Ziel ist es, die Neuartigkeit und das Spezifische der Neurotechnologien – über die bisherigen (...) Untersuchungen hinaus – hinsichtlich des Umgangs mit sich selbst herauszuarbeiten und greifbar zu machen. Abschließend werden auf Basis der Analyse der Patienten-Narrationen die entsprechenden normativen Implikationen für eine ethische Bewertung des Einsatzes von Neurotechnologien benannt. (shrink)

Over the last decade, the increased use of work teams within organizations has been one of the most influential and far-reaching trends to shape the business world. At the same time, corporations have continued to struggle with increased unethical employee behavior. Very little research has been conducted that specifically examines the developmental aspects of employee ethical decision-making in a team environment. This study examines the impact of a team leader’s perceived integrity on his or her subordinates’ behavior. The results, which (...) came from a survey of 245 MBA students functioning for 2 years in a work team environment, indicate an interaction between leader integrity and team member ethical intentions. (shrink)

Ontologies, as the term is used in informatics, are structured vocabularies comprised of human- and computer-interpretable terms and relations that represent entities and relationships. Within informatics fields, ontologies play an important role in knowledge and data standardization, representation, integra- tion, sharing and analysis. They have also become a foundation of artificial intelligence (AI) research. In what follows, we outline the Coronavirus Infectious Disease Ontology (CIDO), which covers multiple areas in the domain of coronavirus diseases, including etiology, transmission, epidemiology, pathogenesis, diagnosis, (...) prevention, and treatment. We emphasize CIDO development relevant to COVID-19. (shrink)

Although the biological bases of forgetting remain obscure, the consensus among cognitive psychologists emphasizes interference processes, rejecting decay in accounting for memory loss. In contrast to this view, recent advances in understanding the neurobiology of long-term memory maintenance lead us to propose that a brain-wide well-regulated decay process, occurring mostly during sleep, systematically removes selected memories. Down-regulation of this decay process can increase the life expectancy of a memory and may eventually prevent its loss. Memory interference usually occurs during certain (...) active processing phases, such as encoding and retrieval, and will be stronger in brain areas with minimal sensory integration and less pattern separation. In areas with efficient pattern separation, such as the hippocampus, interference-driven forgetting will be minimal, and, consequently, decay will cause most forgetting. (shrink)

On virtue ethical grounds, Barbro Fröding and Martin Peterson recently recommended that near-future AIs should be developed as ‘Friendly AI’. AI in social interaction with humans should be programmed such that they mimic aspects of human friendship. While it is a reasonable goal to implement AI systems interacting with humans as Friendly AI, I identify four issues that need to be addressed concerning Friendly AI with Fröding’s and Peterson’s understanding of Friendly AI as a starting point. In a first step, (...) I briefly recapitulate Fröding’s and Peterson’s arguments for Friendly AI. I then highlight some issues with Fröding’s and Peterson’s approach and line of reasoning and identify four problems related to the notion of Friendly AI, which all pertain to the role and need for humans’ moral development. These are that one should consider the moral tendencies and preferences of the humans interacting with a friendly AI, it needs to be considered whether the humans interacting with a Friendly AI are still developing their virtues and character traits, the indirect effects of replacing humans with Friendly AI should be considered with respect to the possibilities for humans to develop their moral virtues and that the question whether the AI is perceived as some form of Artificial General Intelligence cannot be neglected. In conclusion, I argue that all of these four problems are related to humans moral development and that this observation strongly emphasizes the role and need for humans moral development in correlation to the accelerating development of AI-systems. (shrink)

In ancient literature and religion, Hercules—in common with many other deities—is frequently associated with particular trees or types of tree. There are tales connecting him with the wild olive, laurel and oak, but his most prominent and frequent arboreal link is with the poplar, an association mentioned twice in the Hercules-heavy first half of Aeneid Book 8. The festival of Hercules celebrated by Evander and his people takes place just outside the city within a ‘great grove’ of unspecified species, in (...) an area surrounded by less defined expanses of trees. Trees crowd the banks of the Tiber, leaning out for wonder as Aeneas’ fleet passes by and soon uariisque teguntur | arboribus, uiridisque secant placido aequore siluas ; looking up through the sacrificial smoke on the altars, Pallas and his friends are initially frightened ut celsas uidere rates atque inter opacum | adlabi nemus. When Evander later shows Aeneas around, the emphasis on trees recurs, with the huge grove destined to become Romulus’ Asylum, and the bramble- and god-haunted woods of the Capitol. Later, Aeneas and his men camp in a vast grove of Silvanus, as Venus approaches to bring her son his new shield. (shrink)

Es ist vermutlich kein Zufall, dass zu den ersten Maschinen, mit denen Menschen interagierten, auch Illusionsmaschinen gehörten. Die Theater im antiken Griechenland besaßen kranartige Vorrichtungen, die es erlaubten, Schauspieler überraschend in die Bühnenhandlung hineinschweben und eingreifen zu lassen, Götter mimend, die das Geschehen nach ihren Wünschen lenken konnten. Bekannt ist diese Theatertechnik als ›Deus ex machina‹.

Nudges have become a popular tool for behaviour change; but, some interventions fail to replicate, even when the identical, previously successful intervention is used. One cause of this problem is that people default to using some of or all of the previously-successful existing nudges for any problem—the “kitchen sink” approach. We argue that the success of an intervention depends on understanding people’s current behaviour and beliefs to ensure that any nudge will actually “budge” them from their current beliefs. We introduce (...) the Beliefs–Barriers–Context model, with three components: understanding beliefs, barriers, and context to change behaviour through a budge. Designing a budge has the goal of identifying the psychological mechanism that drives a target behaviour, focusing on the psychology of the target population before attempting to change that behaviour. In contrast to the “kitchen sink” approach, budges are best complemented with mechanism experiments to identify what undergirds behaviour change. Moving away from simply nudging behaviour to budging minds—by understanding beliefs, barriers and context—has the potential to inform both the successes and failures of behavioural interventions. (shrink)

One of the most effective ways of winning an argument is to show that your opponent has begged the question. If you are sufficiently skilful in asking him leading questions and have a good sense of timing you can usually succeed in stripping him to his bare principles, with no ascertainable means for their support. That such a tactic of debate should be so effective suggests that it is more than just a ploy. Indeed some philosophers would say that it (...) takes advantage of a characteristic which is inherent in the nature of argument itself, for all arguments must be question-begging. However, few would voice this conviction publicly—for fear of being accused of begging the question. (shrink)

: In this paper I discuss two puzzles that concern the sense in which consciousness can be described as ‘continuous’. The first puzzle arises out of recent work by Dainton and Tye, both of whom appear to oscillate between ascribing the property of ‘continuity’ to the stream of experience, and ascribing it to the objects of experience. The second puzzle concerns the notion that the stream of consciousness could be in some sense unreal or illusory—a puzzle stemming from the thought (...) that some of the brain processes underlying consciousness do not exhibit continuity. I argue that these problems can be solved by distinguishing between three possible bearers of the property of ‘continuity’—(1) the State of Consciousness, (2) the Stream of Experience, and (3) what is represented by experience—and two different senses of ‘continuity’—‘strict’ and ‘extreme’ continuity. I conclude by providing a positive account of the continuity of consciousness, according to which the State of Consciousness exhibits ‘strict’ continuity, and the Stream of Experience exhibits ‘extreme’ continuity. (shrink)

Urban street trees (USTs) have a range of values – some of which are easier to quantify than others. Focusing specifically on the UK context and using the Sheffield Tree Protests (2012–) as a case study, whilst confirming existing research as to the variety of values associated with their specifically ‘cultural’ services, the article argues that USTs have an additional potential form – what I call ‘civic-transformative value’. This form of value has at least three key characteristics. Firstly, it is (...) place-based and communal; second, its form is ‘relational’; and finally, as intrinsically contingent, it is pluralistic in the sense that its civic-transformative potential is dependent on successfully integrating a range of other values. The article emphasises both the possibility and necessity of ‘convergence’ – that is, a pluralistic and pragmatic alliance of values which might help protect not only USTs, but other embattled sites of nature. (shrink)

ArgumentDiscussions of the scientific uses of moving-image technologies have emphasized applications that culminated in static images, such as the chronophotographic decomposition of movement into discrete and measurable instants. The projection of movement, however, was also an important capability of moving-image technologies that scientists employed in a variety of ways. Views through the microscope provide a particularly sustained and prominent instance of the scientific uses of the moving image. The category of “education” subsumes theses various scientific uses, providing a means by (...) which to bridge the cultures of scientific and popular scientific moving images. (shrink)

Funniness, a property the nature of which is both seemingly obvious and yet resistant to analysis, has been the object of intermittent attention in philosophy since Plato. Sometimes this attention has taken the form of an investigation into the nature of laughter and the humorous. Sometimes it has taken comic art-forms as its object, though tragedy has received a good deal more attention from philosophers. And sometimes it has focused on jokes and put-downs in their considerable variety, and ethical questions (...) associated with them. All these inquiries are, of course, interlinked. In this paper, we focus on the ethics of jokes, but will then draw connections between that issue and the question of the ethical dimension of humor in put-downs and in art. Our inquiry is thus part of a larger investigation in aesthetics on the relation between artistic and moral value generally. (shrink)