In her article, Pascale Hess raises the issue of whether her proposed model may be extrapolated and applied to clinical research fields other than stem cell-based interventions in the brain (SCBI-B) (Hess 2012). Broadly summarized, Hess’s model suggests prioritizing efficacy over safety in phase 1 trials involving irreversible interventions in the brain, when clinical criteria meet the appropriate population suffering from “degenerative brain diseases” (Hess 2012). Although there is a need to reconsider the traditional phase 1 model, especially with respect (...) to first-in-human clinical trials involving novel technologies, the question arises as to whether it is appropriate to advocate for a new model that prioritizes efficacy over safety across all phase 1 clinical research trials involving irreversible interventions in the brain. -/- . (shrink)

Every pharmacist, aware or not, is constantly making ethical choices. Sometimes these choices are dramatic, life-and-death decisions, but often they will be more subtle, less conspicuous choices that are nonetheless important. Assisted suicide, conscientious refusal, pain management, equitable and efficacious distribution of drug resources within institutions and managed care plans, confidentiality, and alternative and non-traditional therapies are among the issues that are of unique concern to pharmacists. One way of seeing the implications of such issues and the moral choices they (...) pose is to look at the experiences of practitioners and the kinds of choices they have had to make in situations typically faced by pharmacists. This book is a collection of those situations based on the real experiences of practicing pharmacists. The use of case studies in health care ethics is not new, but in pharmacy it is. This text is an important teaching tool that will help pharmacy students and pharmacists address the increasing number of ethical problems arising in their profession. It is not merely a compilation of cases, but rather is organized for the systematic study of applied ethics. Part I shows how to distinguish ethical problems from other kinds of evaluative judgments and examines the sources of values in pharmacy, posing basic questions about the meaning and justification of ethical claims. Part II explores the basic principles of ethics as they have an impact on pharmacy. Specific cases from clinical settings present in a systematic way the various questions raised by each of the major ethical principles -- benefiting the patient, distributing resources justly, respecting autonomy, dealing honestly with patients, keeping promises of confidentiality, and avoiding harm. Part II examines some of the special problems of contemporary pharmacy such as the linkages between pharmaceutical care and professional practice, human experimentation, reproductive issues, genetic technology, death and dying, and mental health. (shrink)

It was of course impossible for Mr. Miller within the limits of his paper to follow out all the implications of his position, and I merely want to raise some questions with regard to a few of the more important of these implications. If Plato assumed the role of historian, intent on giving an "accurate representation" of his characters in conversations that actually took place, it would clearly be incumbent on him to keep any independent philosophical interest of his own, (...) if he had any, completely out of the picture-his interest in philosophy was limited to reporting what Socrates, Protagoras, Gorgias, and the others had said on various subjects. Now, the only dialogues in which Socrates does not do the constructive thinking are a small group, consisting of the Sophist, Statesman, Timaeus, Critias, Laws, and Epinomis, written towards the end of Plato's life; but I am not certain whether Mr. Miller holds that these represent a continuance of the reporting function, or a sudden outburst of originality by Plato. The question that I would ask therefore is whether Mr. Miller's thesis would imply that Plato was merely an accurate reporter of other men's opinions either all his life or at least down to the last ten or fifteen years. (shrink)

_First Philosophy: Values and Society_ brings together classic and ground-breaking readings on ethics and political philosophy. Andrew Bailey’s highly regarded introductory anthology has been revised and updated in this new edition. The comprehensive introductory material for each chapter and selection remains, and new sections on philosophical puzzles and paradoxes and philosophical terminology have been added. New to this edition is an article by Susan Moller Okin on justice and gender.

The emergence of the “4th Industrial Revolution,” i.e. the convergence of artificial intelligence, the Internet of Things, advanced materials, and bioengineering technologies, could accelerate socioeconomic insecurities and anxieties or provide beneficial alternatives to the status quo. In the post-Covid-19 era, the entities that are best positioned to capitalize on these innovations are large firms, which use digital platforms and big data to orchestrate vast ecosystems of users and extract market share across industry sectors. Nonetheless, these technologies also have the potential (...) to democratize ownership, broaden political-economic participation, and reduce environmental harms. We articulate the potential sociotechnical pathways in this high-stakes crossroads by analyzing cellular agriculture, an exemplary 4th Industrial Revolution technology that synergizes computer science, biopharma, tissue engineering, and food science to grow cultured meat, dairy, and egg products from cultured cells and/or genetically modified yeast. Our exploration of this space involved multi-sited ethnographic research in both the cellular agriculture community and alternative economic organizations devoted to open source licensing, member-owned cooperatives, social financing, and platform business models. Upon discussing how these latter approaches could potentially facilitate alternative sociotechnical pathways in cellular agriculture, we reflect upon the broader implications of this work with respect to the 4th Industrial Revolution and the enduring need for public policy reform. (shrink)

Currently the Enlightenment tradition is under such intense attack that Richard Bernstein calls the present mood a “rage against the enlightenment.” The purpose of this essay is to defend the deep spirit of the Enlightenment, the position that no idea, proposition, or principle should be beyond critical assessment. The defense involves an examination of and a response to two criticisms of the Enlightenment: first that the Enlightenment disdainfully rejects religion, particularly Christianity, and second that Enlightenment thinkers had a misguided confidence (...) in the powers of a-historical reason, i. e. the notion that humans have a rational capacity, unaffected by context or historical circumstance, to arrive at truth. (shrink)

How should we understand the emotional rationality? This first part will explore two models of cognition and analogy strategies, test their intuition about the emotional desire. I distinguish between subjective and objective desire, then presents with a feeling from the "paradigm of drama" export semantics, here our emotional repertoire is acquired all the learned, and our emotions in the form of an object is fixed. It is pretty well in line with the general principles of rationality, especially the lowest reasonable (...) principles. Turned to the second part of this side of reasonable. I will inquire how emotional beliefs, desires, and behaviors contribute to the rationality. I will present a very general biological hypothesis: emotions by controlling highlights the characteristics of perception and reasoning, so that we remove the difficulties due in particular to lead to paralysis; they are being simulated by a simplified perception of information, thus limiting our practice and cognitive choice. How are we to understand emotional or axiological rationality? I pursue analogies with both the cognitive and the strategic models, testing them against intuitions about emotional desires. We distinguish two different classes of desires, the subjective and the objective, and propose that emotions have a semantics that derives from "paradigmatic scenarios", in terms of which our emotional repertoire is learned and the formal objects of our emotions fixed. This fits in well with emerging facts about how our emotional capacities develop, and it can also be squared with the general principles of rationality, particularly minimal rationality. In the second part, I return to the perspective of rationality. I ask how emotions contribute to the rationality of beliefs, desires, and behavior. I proffer a very general biological hypothesis: Emotions spare us the paralysis potentially induced by a particular predicament by controlling the salience of features of perception and reasoning; they temporarily mimic the informational encapsulation of perception and so circumscribe our practical and cognitive options. (shrink)

In this article, I demonstrate fundamental weaknesses in the ability of critical understandings of race to produce reliable knowledge of how social actors use social comparisons as a way to align self with ingroup. I trace these weaknesses to two sources: The first is relying on social status as an explanation for race-based assessments, ingroup motivations, and social constructions of otherness. This is opposed to leaning on assessments grounded in social psychological research that links properties of human cognition to the (...) development and maintenance of social identities. The second weakness is an open support for activist research that is often situated in radical multiculturalism. Because critical race scholars openly side with racial minorities’ interests, they tend to establish incomplete assessments of social behaviors and social constructs linked to racial identities in order to maintain their stated political allegiances. To demonstrate these and other weaknesses, I draw upon the theoretical insights of social identity theory which is used to reassess Bell and Hartmann's (2007) critical race analysis of diversity dialogue in American society. (shrink)

The puzzling case of the broken arm -- Hernias, diets, and drugs -- Why physicians cannot know what will benefit patients -- Sacrificing patient benefit to protect patient rights -- Societal interests and duties to others -- The new, limited, twenty-first-century role for physicians as patient assistants -- Abandoning modern medical concepts: doctor's "orders" and hospital "discharge" -- Medicine can't "indicate": so why do we talk that way? --"Treatments of choice" and "medical necessity": who is fooling whom? -- Abandoning informed (...) consent -- Why physicians get it wrong and the alternatives to consent: patient choice and deep value pairing -- The end of prescribing: why prescription writing is irrational -- The alternatives to prescribing -- Are fat people overweight? -- Beyond prettiness: death, disease, and being fat -- Universal but varied health insurance: only separate is equal -- Health insurance: the case for multiple lists -- Why hospice care should not be a part of ideal health care I: the history of the hospice -- Why hospice care should not be a part of ideal health care II: hospice in a postmodern era -- Randomized human experimentation: the modern dilemma -- Randomized human experimentation: a proposal for the new medicine -- Clinical practice guidelines and why they are wrong -- Outcomes research and how values sneak into finding of fact -- The consensus of medical experts and why it is wrong so often. (shrink)

The Turing Test, originally proposed as a simple operational definition of intelligence, has now been with us for exactly half a century. It is safe to say that no other single article in computer science, and few other articles in science in general, have generated so much discussion. The present article chronicles the comments and controversy surrounding Turing's classic article from its publication to the present. The changing perception of the Turing Test over the last fifty years has paralleled the (...) changing attitudes in the scientific community towards artificial intelligence: from the unbridled optimism of 1960's to the current realization of the immense difficulties that still lie ahead. I conclude with the prediction that the Turing Test will remain important, not only as a landmark in the history of the development of intelligent machines, but also with real relevance to future generations of people living in a world in which the cognitive capacities of machines will be vastly greater than they are now. (shrink)

In this article, I follow up on a suggestion made by Josephine Donovan that a Hume-inspired ethic of sympathy would be a better foundation for an animal ethic than more rationalistic approaches of both utilitarianism and deontology. I then expand on Donovan’s suggestion by further suggesting that Hume’s “sentiment of humanity” could easily be expanded to include other animals. Hume’s ethic of sympathy, I argue, answers the need for an ethic that is at once both personal, contextual, and sufficiently universalizable (...) to incorporate the political need for something like justice. I say, “something like justice,” because animals are explicitly ruled out of justice relationships by Hume due to his more narrow definition of that term. What I mean by “something like justice” is a more impersonal and objective element that transcends exclusively personal or private interests. (shrink)

A reassessment of Aquinas’s doctrine of divine infinity, particularly in the light of the previous history of the concept within Western philosophy and theology. From the critical perspective provided by this history the central place which has been claimed for it in Aquinas’s thinking is questioned, as are also its originality and coherence. The notion that the doctrine of divine infinity was introduced to Western thought by Judaeo‐Christianity is rejected; from Anaximander onwards it had been a central concept in Greek (...) philosophy. Aristotle however had rejected it so effectively that, for several centuries afterwards, it seems to have led an ‘underground’ existence until it finally surfaces again in ‘Gnostic’ and related currents of thought. It is from these circles that it finally, and after some resistance, patchily entered orthodox Christian thinking. Likewise Plotinus was not the source of the doctrine, as some have claimed; historical precedence must be given to the Gnostics. Neoplatonism never, despite the prestige of Plotinus, fully accepted the doctrine; in Proclus it is a subordinate emanation from the One, which is beyond Infinity and Infinitude. Nor, because of the influence of Aristotle, does Islamic Neoplatonized Aristotelianism endorse the doctrine. Aquinas’s commitment to it seems to stem from the impact of John of Damascus’s stress upon the doctrine, the translation of whose work greatly influenced Western theology from the late twelfth century onward, together with his need to distance himself from the restrictions of the divine power and freedom found in the Arabic Aristotelian philosophers, whom, in general, he regarded as philosophical authorities. But his position on the doctrine is flawed by equivocation and self‐contradiction, flowing from his attempt to reconcile Christian personalist theism with Neoplatonized Aristotleain necessitarian monism. (shrink)

An ascent routine (AR) allows a speaker to self-ascribe a given propositional attitude (PA) by redeploying the process that generates a corresponding lower level utterance. Thus, we may report on our beliefs about the weather by reporting (under certain constraints) on the weather. The chief criticism of my AR account of self-ascription, by Alvin Goldman and others, is that it covers few if any PA’s other than belief and offers no account of how we can attain reliability in identifying our (...) attitude as belief, desire, hope, etc., without presupposing some sort of recognition process. The criticism can be answered, but only by giving up a tacit—and wholly unnecessary—assumption that has influenced discussions of ascent routines. Abandoning the assumption allows a different account of ARs that avoids the criticism and even provides an algorithm for finding a corresponding lower level utterance for any PA. The account I give is supported by research on children’s first uses of a propositional attitude vocabulary. (shrink)

Andrews, Robert M A way of dealing with historical episodes, the consequences of which continue to challenge us, is to ask a counterfactual-a 'what if?' question. Martin Luther's life, his critique of the Catholic Church, his challenge to the social and political hegemony of European Catholicism, the resultant splintering of an ecclesial unity assumed by the medieval mind to be practically impenetrable, is one such historical episode. My counterfactual is as follows: What would have been the consequences to European (...) Catholicism had Luther not rebelled against the church? As this article will later discuss, Luther famously spent many hours in the confessional during his time as an Augustinian friar. Luther's superior, spiritual guide, and confessor, Johann von Staupitz -whose motto was 'I am yours, save me'-often assured Luther that his sins were forgiven, that Christ's work had been done, and that he consequently had no need to despair of the mercy of God. It was advice that Luther ultimately found unsatisfactory. 'I did not love, no, rather I hated the just God who punishes sinners', Luther famously said in 1545, reflecting on his time as a monk, articulating a conscience that found solace only outside of Roman communion. (shrink)

Given the profound public health and economic ramifications of decisions made by the U.S. Food and Drug Administration, the degree to which FDA activities should reflect an approach founded on complete transparency versus one focused on preserving confidentiality of information deserves public discussion. On one hand, reasonable requirements for transparency are critical to stimulating effective innovation, knowledge dissemination, and good business practice. On the other, ensuring the vitality of the medical products industry requires protecting legitimately proprietary information. With current standards (...) reflecting a lengthy accumulation of legal, regulatory, and practical precedent, recent significant changes in the environment in which the FDA operates should prompt a critical examination of current practices. In this article, I comment on Sharfstein and colleagues’ “Blueprint for Transparency,” which calls for multiple specific actions to increase transparency at the agency across five key areas, including interactions between FDA and industry, public disclosure of internal FDA analyses, deliberations concerning generics and biosimilars, expanded access to raw study data, and approaches to countering misleading information in the public sphere. I evaluate these recommendations in light of my experience as a clinician, researcher, and former FDA Commissioner, and reflect on possible outcomes that could result from enacting these practices. (shrink)

When The Ad Hoc Committee of Harvard Medical School to Examine the Definition of Brain Death began meeting in 1967, I was a graduate student, with committee member Ralph Potter and committee chair Henry Beecher as my mentors. The question of when to stop life support on a severely compromised patient was not clearly differentiated from the question of when someone was dead. A serious clinical problem arose when physicians realized that a patient's condition was hopeless but life support perpetuated (...) body function. Thus, the committee stated that its first purpose was to deal with the burdens on patients and families as well as on hospitals and on patients needing hospital beds occupied by comatose patients. They intuited the strategy of “defining” these patients as dead, thus legitimating treatment stoppage. They noted that this would also serve a second purpose. Although the dead donor rule had not yet been clearly articulated, they claimed that defining patients as dead would also address controversy over obtaining organs for transplant.My mentors’ discussions related to my interest in the intersection between questions primarily of medical fact (When has a human brain irreversibly ceased functioning?) and nonmedical questions of social policy (Should we treat individuals with dead brains and beating hearts as dead humans?). It quickly became clear that most committee members did not appreciate the interplay of these questions. (shrink)

On reading the grain argument as advanced by Meehl and Sellars, I find that there is not one but two grain arguments. According to one argument, mental events cannot be the same as neural events because mental events have a continuity that neural events do not have. The other argues for the same conclusion from the simplicity of experienced quality. I answer these arguments by claiming that these properties of experience are illusory. I detail a dual threshold theory of visual (...) experience and show that given this model the mind-brain identity theory predicts the existence of these illusions. (shrink)

I argue that there is no conflict between the simulation theory, once it is freed from certain constraints carried over from theory theory, and Gallagher's view that our primary and pervasive way of engaging with others rests on 'direct', non-mentalizing perception of the 'meanings' of others' facial expressions, gestures, and intentional actions.

Alvin Goldman's early work in action theory and theory of knowledge was a major influence on my own thinking and writing about emotions. For that reason and others, it was a very happy moment in my professional life when I learned, in 1988, that in his presidential address to the Society for Philosophy and Psychology Goldman endorsed and defended the “simulation” theory I had put forward in a 1986 article. I discovered afterward that we share a strong conviction that empirical (...) evidence is relevant to a full assessment of the theory. We both find the burgeoning evidence from cognitive neuroscience to be of particular interest, I believe, in part because it makes possible a major departure for the philosophy of mind: turning its attention from " the neural basis of mental states, " to. (shrink)

I attempt to show that when someone is, E.G., Angry about something, The events or states that conjointly are causing him to be angry conform to a certain structure, And that from the causal structure underlying his anger it is possible to 'read out' what he is angry about. In this respect, And even in some of the details of the structure, My analysis of being angry about something resembles the belief-Want analysis of intentional action. The chief elements of the (...) causal structure I describe are a belief and an attitude so related in content as to constitute either a wish-Frustration (in the case of negative emotions) or a wish-Satisfaction (in the case of positive emotions). The analysis makes otiose, In those cases for which it is a correct analysis, The mysterious non-Causal relation between an emotion and its 'object' which is invoked by the majority of philosophers now writing on emotions. (shrink)

I want to begin by saying that the terms of reference of this series of lectures grated on me, in particular, the word ‘power’. One thing it conjured up was the criticism made by people who say we use our power over our patients to brainwash them, that the psychotherapeutic relationship is inescapably authoritarian, domineering, coercive. This was widely said in the sixties by leftist and feminists and others who sought a therapeutic relationship that was more equal, co-counselling, for example, (...) where the client and the therapist took turns exposing their problems. In my experience, most people who took up that position eventually saw the merits of relatively orthodox psychotherapy, and many have trained in conventional psychodynamic psychotherapy. I asked my partner, who is also a psychoanalytic psychotherapist, what the term power conjured up for her and got an uncharacteristically sharp response. She said, ‘I hate that word. It’s used by humanistic therapists who are afraid of authority, difference and knowledge and want us all to be the same. It’s like saying colour doesn’t matter. They confuse the abuse of power with the use of power. They assume that all exercise of power is abusive.’. (shrink)

Discussions about “disruptive” food controversies abound in popular and academic literatures, particularly with respect to meat production and consumption, yet there is little scholarship examining what makes an event disruptive in the first instance. Filling this gap will improve our understanding of how food controversies unfold and why certain issues may be more likely to linger in the public consciousness as opposed to others. I address these questions by using focus groups and in-depth interviews to analyze five potentially upsetting topics: (...) dietary warnings about meat consumption, meat safety recalls, eating meat directly from the skull of the animal, the morality of killing animals for food, and the “pink slime” debate. Findings suggest that disruptive events involve negative affective reactions to safety hazards, disgust-provoking sensory cues, and/or ethical dilemmas. When these cues exist in isolation from one another, consumers’ reactions are quite often short-lived, while the simultaneous presence of multiple disruptive elements in the context of a single issue or event can trigger a far stronger reaction. (shrink)

I argue that there is a tension between three popular views in the philosophy of mind: (1) mental properties are not identical with physical properties (a version of nonreductionism), but (2) mental properties are had solely by virtue of physical properties (physicalism regarding the mind), which requires that (3) mental properties supervene on physical properties. To earn the title "physicalist," one must hold a sufficiently strong version of the supervenience thesis. But this, I argue, will be a version that undermines (...) nonreductionism. (shrink)

Clinical ethics consultants respond to a multitude of issues, ranging from the cognitive to the emotional. As such, ethics consultants must be prepared to analyze as well as empathize. And yet, there remains a paucity of research and training on the interpersonal and emotional aspects of clinical ethics consultations—the so-called skills in “advanced ethics facilitation.” This article is a contribution to the need for further understanding and practical knowledge in the emotional aspects of ethics consultation. In particular, I draw attention (...) to defense mechanisms: what they are, why they exist, and how we might work with them in the setting of ethics consultation. (shrink)

Many of the elements of the problem of implementation have been assembled in Philip McShane’s paper and addressed in his life’s work to date. The dimension to which I wish to contribute is the need to lift the chapter on Systematics in Method in Theology out of its tired and minimalist context into the context that Lonergan seems to have had in mind when, at the time of the breakthrough to functional specialization, what eventually was called Systematics was named ‘Explanation’ (...) and its mediated object was said to be Geschichte. At that point Lonergan had in mind, I submit, not simply summing up and integrating the dogmatico-theological context – and even that task does not emerge clearly in Method’s chapter – but also advancing that context, in fact catapulting it into the third stage of meaning and onto the plateau where a normative source of meaning has been articulated that, while remaining normative, pays full recognition to historical mindedness. (shrink)

I argue for the inadequacy of the Kantian approach to the analysis of personal relations in business presented by Moberg and Meyer, in A Deontological Analysis of Peer Relations in Organizations (Journal of Business Ethics). It is unclear or implausible that the (mostly reasonable) principles of business relations they advocate really do follow from Kant's theory. Kant's theory, and deontological theories in general, do not yield reasonable principles of personal relations, particularly in the business context.

When I arrived at Harvard as an incoming graduate student in the fall of 1964, I soon received a telephone call from a gentleman who introduced himself as Henry Beecher. I was in the process of shifting my graduate studies from research neuropharmacology to the study of ethics. Robert Featherstone, the head of the Department of Pharmacology at the University of California Medical Center, San Francisco, where I had been studying, was a specialist in anesthesiology and knew Henry Beecher, (...) who was also working in anesthesiology, well. He had contacted Beecher, alerting him to the fact that a new graduate student was arriving and that it appeared that the two of us had much in common. The phone call from Beecher... (shrink)

Schneiderman, Jecker, and Jonsen disagree with two recent policy statements of professional medical organizations over whether to call some medical interventions “inappropriate” or “potentially inappropriate” that have previously been labelled “futile.” I would agree that inappropriate is a hopelessly ambiguous term that should not be used in the long-running debate, more normally referred to as the futility controversy. I find, however, that Schneiderman, Jecker, and Jonsen end up with the same policy conclusion as the two policy statements. When patients or (...) their surrogates disagree with clinicians about whether to provide certain treatments, they all... (shrink)

We attempt to gain some insight into the issue of whether pure states evolve to density matrices in the black hole evaporation process by examining the mode functions of the particles entering the black hole which are correlated with the particles which escape to infinity. We show that these particles enter the black hole singularity at relatively early times. This tends to support the view that pure states evolve to density matrices, i.e., that in this process quantum coherence is lost.

Clinical ethics consultants often confront the most difficult clinical encounters, typically in the setting of chronically critically ill patients and surrogate decision makers. These encounters require not only analytical skills but interpersonal skills as well. In this article, I focus on an interpersonal skill absent from the American Society for Bioethics and the Humanities Task Force’s Core Competencies for Healthcare Ethics Consultation. I introduce the psychoanalytic concept of transference and argue that knowledge and use of transference phenomena are sometimes indispensable (...) for ethics consultation with surrogate decision makers. For solicitation of moral views, disclosure of relevant beliefs and values, and identification of the central ethical question—essential to assessment and analysis—cannot at times begin without recognition and working through of transference. (shrink)

Searle’s famous attempt at what might loosely be called deriving ought from is has received much critical attention; but the main lines of attack on his attempt have been irrelevant, mistaken, or otherwise defective. I shall here offer an account of what, I feel, really centrally has gone wrong with his attempt. I shall use the version of the derivation attempt which is found in Searle’s book, Speech Acts.The attempted derivation has, as its important steps, the following statements:S uttered the (...) words, “I hereby promise to perform A for you, H.”S promised to perform A for H.S placed himself under a obligation to perform A for H.S is under a obligation to perform A for H.S ought to do A for H. (shrink)

According to one brand of 'externalism', cognitive theories should individuate mental content 'widely'--that is, partly in terms of environmental features. David Marr's theory of vision is often cited in support of this view. Many philosophers (most notably, Tyler Burge) regard it as a prime example of a fruitful cognitive theory that widely individuates the representations it posits. I argue that, contrary to popular belief, Marr's theory does not presuppose an externalist view of mental content.

Ever since Plato’s famous attack on artists and poets in Book 10 of The Republic, lovers of literature have felt pressed to defend poetry, and indeed from ancient times down to the present, literature and art have had to fight various battles against philosophy, religion, and science. After providing a brief overview of this conflict and then arguing that between poetry and science there are some noteworthy similarities---that is, that some of the basic mental structures with which the scientist studies (...) the “text‘ of nature (facts, laws, theories) find their counterparts in ways an informed reader studies the poetic text, I develop what I see as the most important differences between poetry, on the one hand, and science, philosophy, and theology, on the other. These differences lie chiefly in two areas: (1) in the stance that each takes toward language itself and (2) in the stance each takes toward that ancient polarity between the one and the many. The aim of my argument is neither to privilege poetry over the other modes of knowing the world nor to grant, particularly to science in its reductive “objectivity,‘ a higher epistemological status than that accorded to poetry and the arts. Instead, I wish to argue that science, by pushing the boundaries of knowledge about the material world, shows the poet, as well as the theologian, some of the more important work to be done and that poetry, with its emphasis on the particular over the abstract and on the ambiguities and paradoxes of language as inherently metaphorical, serves science and religion by providing a caution against the naive acceptance of language as literal and the consequent enthrallment to the power of absolutes and totalizing abstractions. (shrink)

It is widely thought among philosophers that Joseph Butler's criticism of psychological egoism in his Sermons is, in the words of A.E. Duncan-Jones, 'the classic refutation of it.' Indeed, no less a philosopher than David Hume restated and put forth Butler's central argument against hedonistic egoism - without due credit - as part of his own critique. Yet recent commentators have begun to question Butler's arguments, albeit usually with sympathy and in the hope of saving what they take to be (...) his insights. I propose to focus on Butler's main objection to hedonistic psychological egoism, to show how and why it fails to refute plausible forms of the thesis, and briefly to indicate why philosophical attempts to disprove this theory of motivation are misguided. (shrink)

Most recent writing linking science and literature has concerned itself with challenges to the epistemological status of scientific knowledge in an attempt to demonstrate its contingency, arguing in the more radical efforts that the structures of science are no more than useful fictions. This essay also includes an epistemological comparison between science and literature, but instead of making grand or meta–statements about the nature of knowing generally in the two fields, mine is a much narrower aim. My exploration entails two (...) tasks. First, I provide a close–up look at a particular type of experiment, called the delayed–choice experiment, which clearly reveals the strangeness of the quantum world. In connection with this experiment, I discuss wave functions—mathematical expressions used by physicists to describe quantum behavior and predict the outcome of experiments involving quanta. Second, I look at Walt Whitman's “Song of Myself” focusing on the meaning of the “self” in the poem. My aim is to treat the object of study in each field as a “text” and to assert and demonstrate a parallel in the strategies of thought and response between physicists (“readers”) pondering the meaning and status of a wave function and poem readers pondering the meaning and status of the poem's self. In Whitman's “Song” we find an attempt to understand complex aspects of human experience that are said to transcend ordinary reality, an effort for which I believe there are parallels in the attempts of modern physicists to understand complex, nonintuitive aspects of the subatomic world. While not making the kind of broad claims eschewed above, I do suggest that this focused study has interesting implications since both the wave function and the poem's self force their respective sets of “readers” to confront questions of ultimacy—to consider, that is, epistemological and ontological issues of more than passing interest to students of science as well as those of metaphysics and theology. (shrink)

Agent-relativity, as an attribute of principles for moral decision, reasons for action, and values, has been a topic of discussion in recent ethical theory primarily in the context of objections to act-consequentialism. Thus, Samuel Scheffler explains that act-consequentialist theories “first specify some principle for ranking overall states of affairs from best to worst from an impersonal point of view.” These rankings are not agent-relative, i.e., “they do not vary from person to person, depending on what one’s particular situation is.” Scheffler (...) notes that this is because “they do not embody judgements about which overall states of affairs are best for particular individuals, but rather judgements about which states of affairs are best, all things considered, from an impartial standpoint.” Act-consequentialism then directs each agent always to bring about the highest-ranked state of affairs that he or she can. (shrink)

The assumption is often made that there cannot be scientific laws about individuals. I shall try to provide a plausible semantics and epistemology for scientific laws about individuals. This would be interesting, however, only if one were tempted to believe that mentioning individuals did not disqualify a sentence from scientific lawhood. To begin with, I will try to provide such a temptation.

Thomas Nagel contends that facts regarding the qualitative character of conscious experience can be grasped from only a single point of view. This feature, he claims, is what renders conscious experience subjective in character, and it is what makes facts about the qualitative experience subjective facts. While much has been written regarding the ontological implications of the ‘point of view account’ relatively Iittle has been said on whether the account itself successfully defines the subjectivity of the mental. In this paper, (...) I show that considerations of what can be grasped from only a single point of view provide neither necessary nor sufficient conditions for subjective experience. (shrink)

Thomas Nagel contends that facts regarding the qualitative character of conscious experience can be grasped from only a single point of view. This feature, he claims, is what renders conscious experience subjective in character, and it is what makes facts about the qualitative experience subjective facts. While much has been written regarding the ontological implications of the ‘point of view account’ relatively Iittle has been said on whether the account itself successfully defines the subjectivity of the mental. In this paper, (...) I show that considerations of what can be grasped from only a single point of view provide neither necessary nor sufficient conditions for subjective experience. (shrink)

Two categorization arguments pose particular problems for localist connectionist models. The internal representations of localist networks do not reflect the variability within categories in the environment, whereas networks with distributed internal representations do reflect this essential feature of categories. We provide a real biological example of perceptual categorization in the monkey that seems to require population coding (i.e., distributed internal representations).