Crowdsourcing platforms are powerful tools for academic researchers. Proponents claim that crowdsourcing helps researchers quickly and affordably recruit enough human subjects with diverse backgrounds to generate significant statistical power, while critics raise concerns about unreliable data quality, labor exploitation, and unequal power dynamics between researchers and workers. We examine these concerns along three dimensions: methods, fairness, and politics. We find that researchers offer vastly different compensation rates for crowdsourced tasks, and address potential concerns about data validity by using platform-specific tools (...) and user verification methods. Additionally, workers depend upon crowdsourcing platforms for a significant portion of their income, are motivated more by fear of losing access to work than by specific compensation rates, and are frustrated by a lack of transparency and occasional unfair treatment from job requesters. Finally, we discuss critical computing scholars’ proposals to address crowdsourcing’s problems, challenges with implementing these resolutions, and potential avenues for future research. (shrink)

t is now well accepted that defined architectural compartments within the cell nucleus can regulate the transcriptional activity of chromosomal domains within their vicinity. However, it is generally unclear how these compartments are formed. The nuclear periphery has received a great deal of attention as a repressive compartment that is implicated in many cellular functions during development and disease. The inner nuclear membrane, the nuclear lamina, and associated proteins compose the nuclear periphery and together they interact with proximal chromatin creating (...) a repressive environment. A new study by Harr et al. identifies specific protein–DNA interactions and epigenetic states necessary to re‐position chromatin to the nuclear periphery in a cell‐type specific manner. Here, we review concepts in gene positioning within the nucleus and current accepted models of dynamic gene repositioning within the nucleus during differentiation. This study highlights that myriad pathways lead to nuclear organization. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Women Are Up to Something: How Elizabeth Anscombe, Philippa Foot, Mary Midgley, and Iris Murdoch Revolutionized Ethics by Benjamin J. B. LipscombAmy Gilbert RichardsLIPSCOMB, Benjamin J. B. The Women Are Up to Something: How Elizabeth Anscombe, Philippa Foot, Mary Midgley, and Iris Murdoch Revolutionized Ethics. New York: Oxford University Press, 2022. xxx + 326 pp. Cloth, $27.95In The Women Are Up to Something, Lipscomb (...) demonstrates in form and content the inextricable link between philosophical theory and personal story and character. The book tells two stories: "first, a story [End Page 148] about four women, their overlapping friendships, and their struggle to establish themselves as philosophers in an often-hostile context; second, a story about two conflicting approaches to ethics." These two stories connect through the role these women played in the development of the second of the conflicting approaches—a challenge to the mid-twentieth-century Oxbridge orthodoxy in metaethics, what Lipscomb later calls a "minority report."Chapter 1 centers on the fact–value divide. The consequence of this divide for ethics lies in its banishment of all evaluative terms from the realm of possible facts, thereby demoting them to matters of "opinion." Lipscomb here offers a genealogy of the divide. He also introduces the insight that will become the seed of the minority report: The picture of the world offered by the fact-value divide is just that, a picture. Bringing to light the deep background pictures that undergird our understanding of the world is one of the most difficult intellectual tasks. But the picture rooted in the fact–value divide includes the claim that the divide itself is simply a "fact"—not a picture at all, and therefore not contestable. Lipscomb labels this view "the Dawkins' sublime."The next three chapters continue the work of stage-setting. Chapter 2 immerses us in the Oxford of the women's undergraduate years—an Oxford temporarily but dramatically altered by World War II, where female students made up a much larger percentage of the undergraduate population than was usual, and where professors were in a new way open to mentoring women. Chapter 3 briefly recounts all four childhoods, lived in the aftermath of the first World War. Chapter 4 returns to Oxford and narrates the graduate degrees of the four women. It also offers a perceptive primer on the history of analytic ethics, culminating in the state of the field at the point when the women were on the cusp of entering it—the precise shape of the approach to ethics the women would eventually abjure.Each of the next four chapters traces the development of the mature philosophy of one of the four women—in order: Murdoch, Anscombe, Foot, and Midgley. Despite deep differences among their philosophical and theological outlooks, they all four came to defend a version of the thesis, commonplace in ancient and medieval philosophy, that there are things that are good for human beings qua human being, that our moral lives are largely a matter of seeing and responding—well or poorly—to these elements of the human good that are given as part of our nature. In other words, there are facts about values. We in crucial ways discover rather than invent morality.The last chapter serves as an epilogue to both stories: It traces the ways in which the writing and lives of these four women produced a decisive change in the landscape of Anglo-American philosophy. Lipscomb notes which strains in contemporary Anglo-American philosophy owe their existence to the minority report. Figures like Korsgaard feature as contemporary representatives of an ethics grounded in the fact–value [End Page 149] divide. Figures like MacIntyre and Hursthouse feature as inheritors of the philosophical legacy of the book's heroines.In this final chapter Lipscomb also offers brief portraits of the later life and death of each of the women in turn. At the end of the final portrait, the book rounds to a poetic close—not offering a final philosophical statement but reflecting on the fruits of friendship and the power of its legacy for those who come after.It is difficult to pin down Lipscomb's precise philosophical... (shrink)

Following Gilbert Ryle’s arguments, many philosophers took it for granted that someone knows how to do something just in case they have the ability to do it. Within the last couple decades, new intellectualists have challenged this longstanding anti-intellectualist assumption. Their central contention is that mere abilities aren’t on the same rational, epistemic level as know how. My goal is to intellectualize know how without over-intellectualizing it. Intelligent behavior is characteristically flexible or responsive to novelty, and the distinctive feature (...) of creatures who exhibit flexible behavior is their capacity to learn. As it turns out, Ryle already identified a core characteristic of learning shared widely across the animal kingdom from the lowly rat to the top athlete. Taking my cues from Ryle, I argue that know how is successful performance resulting from self-regulated abilities. To regulate an ability is to be disposed to adjust to error and respond to feedback. While regulating sophisticated human abilities often requires propositional knowledge, in many simpler cases it does not. I focus on the navigational know how of rats and honeybees. Although they possess know how, whether they possess propositional knowledge is at best an open question. (shrink)

Following Gilbert Ryle’s arguments, many philosophers took it for granted that someone knows how to do something just in case they have the ability to do it. Within the last couple decades, new intellectualists have challenged this longstanding anti-intellectualist assumption. Their central contention is that mere abilities aren’t on the same rational, epistemic level as know how. My goal is to intellectualize know how without over-intellectualizing it. Intelligent behavior is characteristically flexible or responsive to novelty, and the distinctive feature (...) of creatures who exhibit flexible behavior is their capacity to learn. As it turns out, Ryle already identified a core characteristic of learning shared widely across the animal kingdom from the lowly rat to the top athlete. Taking my cues from Ryle, I argue that know how is successful performance resulting from self-regulated abilities. To regulate an ability is to be disposed to adjust to error and respond to feedback. While regulating sophisticated human abilities often requires propositional knowledge, in many simpler cases it does not. I focus on the navigational know how of rats and honeybees. Although they possess know how, whether they possess propositional knowledge is at best an open question. (shrink)

In the 1940s, Gilbert Ryle argued for anti-intellectualism about know how. More recently, new intellectualists have challenged the canonical status of Ryle's arguments, and in the ensuing debate Ryleans appear to be on their back foot. However, contributors on both sides of the debate tend to ignore or misconstrue Ryle's own positive account of know how. In this paper, I develop two aspects of Ryle's positive account that have been overlooked. For Ryle, S knows how to Φ iff (1) (...) S is able to reliably live up to the norms for Φ-ing, and (2) S Φ’s responsibly. In the first half of the paper, I argue that the two conditions rule out the various counter-examples to the simple ability view attributed to Ryle. In the second half of the paper, I argue that Ryle's second condition provides us with an account of warrant related to know how. (shrink)

Hermeneutical injustice occurs when there is a gap in the interpretive resources available to members of a society due to the marginalization of members of a social group from sense‐making practices. In this paper, I address two questions about hermeneutical injustice that are undertheorized in the recent literature: (1) what do we mean when we say that someone lacks the interpretive resources for making sense of an experience? and (2) how do marginalized individuals develop interpretive resources? In response to (1), (...) I argue that to lack interpretive resources is to lack conceptual skill or know how. In response to (2), I draw on resources from Gilbert Ryle and Andy Clark and provide a model of how marginalized individuals develop new conceptual skills by naming their shared experience and using it as a tool for scaffolding each other's conceptual performance. At the same time, I draw on the work of Gaile Pohlhaus and Kristie Dotson to show how these practices succeed only through the redistribution of epistemic power across differently situated social groups. (shrink)

In the 1940s, Gilbert Ryle argued that knowing how to do something is not just a matter of being well-regulated but also a matter of self-regulation. Ryle appears to have thought that know-how requires self-regulation in both a backward-looking and forward-looking sense, but both ideas run counter to ordinary intuitions about know-how. The basic idea behind self-regulation, undertaking trials and adjusting to feedback, is captured by the “law of effect.” Daniel Dennett has argued that the “law of effect will (...) not go away”. After updating Dennett’s “Tower of Generate-and-Test” through a broad survey of the empirical literature on learning, I identify a Rylean intuition about intelligence and argue that self-regulation in a forward-looking sense is necessary for know-how. (shrink)

Many virtue-based approaches to propositional knowledge begin with the ability and achievement intuitions. In this paper, I rely on this pair of intuitions to explore the relationship between knowing how and knowing that. On the view that emerges, propositional knowledge is a kind of success through cognitive know how. Rather than simply equating know how with ability, I reveal deeper connections between both kinds of knowledge by focusing on the role of self-regulation.

In lieu of an abstract, here is a brief excerpt of the content:What Philosophy Can't Say About Literature:Stanley Cavell and EndgameBenjamin H. OgdenIn "Ending the Waiting Game," the philosopher of ordinary language Stanley Cavell attempts to say what Samuel Beckett's Endgame means by explaining what the characters in the play mean by what they say. Cavell attempts to do the very thing that the work says cannot be done, or mocks as foolish and misguided, or resists giving clues to how (...) it could ever be done: he tries to say just "how Beckett's objects mean at all, the original source of their conviction."1 This is not simply a reading tactic that Cavell thinks is well-suited to the difficult task of making sense of a difficult play. It is a demonstration of the theory of language (ordinary language philosophy) that Cavell defends and applies in his collection of essays Must We Mean What We Say?, of which "Ending the Waiting Game" is a chapter. Cavell's literary criticism is in the service of his philosophy. His work of criticism is in search of something that it must find (that is, something that it claims to have found even when it may not have); what it must find is a work of literature that demonstrates the utility and validity of ordinary language philosophy.If we are to take issue with Cavell for too strenuously transposing philosophy onto literature, then we must also know something of the philosophy he draws upon. Ordinary language philosophy traces its origins to Wittgenstein, and was popularized by J. L. Austin and Gilbert Ryle at Oxford in the 1940's. It is a branch of analytic philosophy that foregoes any attempt to create an "ideal philosophical language" of the sort Wittgenstein developed in his early Tractatus Logico-Philosophicus. Instead of seeing the abstractions and ambiguities of ordinary usage as something to be supplanted by a more logically rigorous system, ordinary language philosophers argue that debates over the meaning [End Page 126] of abstract terms come about precisely because words are removed from their ordinary context. For Cavell, the whole idea of an "ideal language" is absurd because, as anyone who has ever tried to learn a foreign language knows, every language has its own unique set of usages and idioms and unspoken rules. In order to speak a language properly, then, one cannot just know the dictionary or formal definitions of words (its "ideal" generative grammar), but must understand the "natural environment" in which phrases and words are logical or appropriate. Often these contexts (which determine the rules for "what we should say when" [p. 20]) invest words with meanings that you won't find in any dictionary, and cannot be catalogued in a grammatical or syntactical system.So, if one asks, "Did you dress that way voluntarily?" (p. 9), the word "voluntarily" takes on a meaning that is not included among its dictionary definitions (according to Cavell). Clearly, in asking whether you dress voluntarily one is not asking whether you have free-will to dress as you please, but is calling attention to the funny way you dress. In this case, successful communication is only possible if the one who is being questioned understands from context and the ordinary use of language precisely what is being asked. If he answers, "Of course I dressed voluntarily, I believe in free will," he will have misspoken, been incorrect. Clearly, he doesn't understand what the question must mean because the statement "MUST MEAN that my clothes are peculiar" (p. 9). For it to mean anything else would be a mistake and a misuse of language by the speaker, or a misunderstanding of language by the listener. To learn a language (which for Cavell means to become like a native speaker) is to learn the nature of the contingency between the explicit meaning of an expression and the occasion on which an expression is appropriate, and to be aware of what you must mean when you speak (what you cannot help but mean or imply by the language you use).What this means is that for Cavell reading literature becomes a process of readers "naturalizing ourselves to a new form of life, a new... (shrink)

Current and recent philosophy of history contemplates a deep change in fundamental notions of the presence of the past. This is called breaking up time. The chief value for this change is enhancing the moral reach of historical research and writing. However, the materialist view of reality that most historians hold cannot support this approach. The origin of the notion in the thought of Walter Benjamin is suggested. I propose a neo-idealist approach called perennialism, centered on recurrent moral dilemmas (...) and choices. This suggests a view of the relations of moral thought and ontology placed in the diachronic context that historians study. (shrink)

The Rococo period in the arts, flourishing mainly from about 1710 to about 1750, was stylistically unified, but nevertheless its tremendous productivity and appeal throughout Occidental culture has proven difficult to explain. Having no contemporary theoretical literature, the Rococo is commonly taken to have been a final and degenerate form of the Baroque era or an extravagance arising from the supposed careless frivolity of the elites, including the intellectuals of the Enlightenment. Neither approach adequately accounts for Rococo style. Naming the (...) Rococo raises profound issues for understanding the relations between conception and production in historical terms. Against the many difficulties that the term has involved in accounting for an immense but elusive cultural movement, this thesis argues that some of the chief philosophical conceptions of the period clarify the particular character and significance of Rococo production. Rococo production is here studied chiefly in decor, architecture, and the plastic arts. This thesis also makes an extended general argument for the value of intellectual history. Rococo style is a group of visual effects of which the central character is atectonicity. This is established by a synthesizing overview of Rococo ornamental motifs. Principal theorists of post-Cartesian thought have failed to see how these distinguish Rococo style from both Baroque and Enlightenment culture. The analysis addresses the historical narratives of Benjamin, Adorno, Foucault, Deleuze, and others about Baroque and Enlightenment culture. The core historical claim of this thesis is that Rococo atectonic effects are visual forms of the anti-materialist, idealist ontology of George Berkeley and of the metaphysics and ontology in the early work of Giambattista Vico. Close readings of important passages from works of both philosophers published in 1710 develop the relationship between atectonics and idealist ontology. Both men rejected the Baroque hierarchical cosmology in favor of finitude as the key to human understanding. The readings center on the issue of causality, including Berkeley’s views of the perfect contingency of the world and on Vico’s theories of truth and ingenium. A reading of Diderot’s critique of the Rococo, which led the reaction to it, shows that he recognized the power of idealist ontology in the Rococo cultural production. The larger force in the rejection of Rococo is the emergence of the sublime as a morally fearful feature of physical nature. Montesquieu’s aesthetic work also shows the transition to a more rigidly determined view of existence, which was expressed but constrained in the little-recognized lattice motif in Rococo arts. The result of these readings is the influence during and after the Rococo period of the concept of continuous creation, in which the memory and imagination of the human subject relays God-given powers of creation into the production of culture. Continuous creation also suggested a human capability to animate material nature. Rococo style displays this as pre-cinematic effects that represent the non-material, non-causal deep structure of reality. (shrink)

Historical study has traditionally been built around the placement of the human at the center of inquiry. The de-stabilized concepts of the human in contemporary thought challenge this configuration. However, the ways in which these challenges provoke new historical perspectives both expand and enrich historical study but are also weak and vulnerable in their concept of the human, lacking or omitting something valuable in our self-understanding. A Personalist Philosophy of History argues for a robust concept of personhood in our experience (...) of the past as a way to resolve this conflict. -/- Focused on those who know history, rather than on the abstract properties of knowledge, it extends the moral agency of persons into non-human, trans-human, and deep history domains. It describes an approach to moral life through historical experience and study, rather than through abstractions. And it describes a kind of historiography that matches factual accuracy to both the constructed nature of understanding and to unavoidable moral purpose. -/- Table of Contents: Introduction Chapter 1. Receiving the Past Chapter 2. Moral Agency Personalism Chapter 3. Shaping Up Time Chapter 4. The Long Experience of Moral Obligation Chapter 5. From Moral Force Ethics to Personalist Philosophy of History . (shrink)

In this essay, we explore the philosophical and theoretical resonances of the artwork Qatipana from the perspective of some key insights of Gilbert Simondon’s information processing system approach. Qatipana (Quechua word that means flow, sequence, transmission) is a hybrid ecosystem of information flow which, even though not the kind of dispositive systems theory was designed to read, offers some valuable empirical insights to test some key aspects of Simondon’s information processing systems. In particular, we are interested in observing how (...) Simondon’s becoming and individuation play out in an algorithmic cycle performed by the cognitive system of an Artificial Intelligence agent: how does mono-technology and computerization of cultural techniques influence the nature of knowing the affection of being with others (people, things, animals)? We contrast Simondon’s contributions with the work of Norbert Wiener and Stafford Beer on information in cybernetics and the cosmotechnics and Technodiversity of Chinese philosopher Yuk Hui. Furthermore, we offer a provisional assessment of the reach, limits, and possibilities this kind of symbiotic crossing of technologies and arts: it is a field filled with challenges and unresolved complexities that should encourage us to recognize the urgency that is implied in the disruptive (and creative) we can see unfolding in social and political life. The already pervasive (and growing) presence of computational systems has become both a tremendous risk and a vertiginous deployment of liberating opportunities. Latin America and elsewhere are desperately calling for an insightful and imaginative engagement. (shrink)

In Testimony, Trust, and Authority, Benjamin McMyler argues that philosophers have failed to appreciate the nature and significance of our epistemic dependence ...

v. 1. Charmides. Lysis. Laches. Protagoras. Euthydemus. Cratylus. Phaedrus. Ion. Symposium.--v. 2. Meno. Euthyphro. Apology. Crito. Phaedo. Georgias. Appendix I: Lesser Hippias. Alcibiades I. Menexenus. Appenddix II: Alcibiades II. Eryxias.--v. 3. Republic. Timaeus. Critias.--v. 4. Pharmenides. Theaetetus. Sophist. Statesman. Philebus.--v. 5 Laws. Index to the writings of Plato.

In _Reliable Reasoning_, Gilbert Harman and Sanjeev Kulkarni -- a philosopher and an engineer -- argue that philosophy and cognitive science can benefit from statistical learning theory, the theory that lies behind recent advances in machine learning. The philosophical problem of induction, for example, is in part about the reliability of inductive reasoning, where the reliability of a method is measured by its statistically expected percentage of errors -- a central topic in SLT. After discussing philosophical attempts to evade (...) the problem of induction, Harman and Kulkarni provide an admirably clear account of the basic framework of SLT and its implications for inductive reasoning. They explain the Vapnik-Chervonenkis dimension of a set of hypotheses and distinguish two kinds of inductive reasoning. The authors discuss various topics in machine learning, including nearest-neighbor methods, neural networks, and support vector machines. Finally, they describe transductive reasoning and suggest possible new models of human reasoning suggested by developments in SLT. (shrink)

In Virtual Worlds, Benjamin Woolley examines the reality of virtual reality.

This essay considers whether palliative sedation is or is not appropriate medical care. This requires one to consider whether, in addition to the good of health, relief of suffering is also a proper end of medicine; whether unconsciousness can ever be a good for a human being; and how double-effect reasoning can help us think about difficult cases. The author concludes that palliative sedation may be proper medical care, but only in a limited range of cases.

This new edition of his "Bioethics features updated information throughout, a fuller discussion of human embryos -- including stem cell research -- and a ...

In a widely noted book, Henry Greely has suggested that “the end of sex” is on the horizon. By this he means that sexual activity for pleasure will be increasingly disconnected from the process by which children are conceived—a result of the growing availability of what he terms Easy PGD. This essay explores the possibility that this sense of an “end” of sex fails to attend adequately to another sense of “end”—namely, the telos that connects human sexual activity to the (...) birth of children. Articulating a Christian understanding of procreation, the essay notes that Easy PGD may invite us to miss the human significance of the connection between the love-giving and life-giving aspects of sexual activity. (shrink)

Common sense tells me I can control my life to some extent; should I then, faced with a logical argument for fatalism, reject common sense? There seems to be no place in a physical theory of the universe for the sensory experiences of colours, taste and smells, yet I know I have these experiences. In this book, Gilbert Ryle explores the conflicts that arise in everyday life and shows that the either/or which such dilemmas seem to suggest is a (...) false dilemma: one side of the dilemma does not deny what we know to be true on the other side. This classic book has been revived in a new series livery for twenty-first-century readers, featuring a specially commissioned preface written by Barry Stroud. (shrink)

To live the risen life with God is, presumably, to be what we are meant to be. What can we conclude about our duties to the dying from the medieval belief that we join the hosts of heaven as “animated earth”?

Many people believe the global economy is unjust, but they don't know what to do about it. What responsibilities do American consumers have to workers in China making their iPhones? Should they still buy clothes made in Bangladesh's sweatshops? Offering an overview of how neoliberalism orients us to the world, Benjamin L. McKean shows the practical shortcomings of neoliberal approaches to the world and develops an alternative way of thinking and acting guided by a compelling new account of freedom. (...) Disorienting Neoliberalism offers a framework for understanding the politics of the global economy and shows how we can act in solidarity to promote justice. (shrink)

Benjamin Barber is one of America's preeminent political theorists. He has been a significant voice in the continuing debate about the nature and role of democracy in the contemporary world. A Passion for Democracy collects twenty of his most important writings on American democracy. Together they refine his distinctive position in democratic theory. Barber's conception of "strong democracy" contrasts with traditional concepts of "liberal democracy," especially in its emphasis on citizen participation in central issues of public debate. These essays (...) critique the "thin representation" of liberal democracy and buttress the arguments presented in Barber's twelve books, most recently in his well-received Jihad vs. McWorld: How Globalism and Tribalism Are Re-shaping the World. In these pieces, Barber argues for participatory democracy without dependence on abstract metaphysical foundations, and he stresses the relationship among democracy and civil society, civic education, and culture. A Passion for Democracy is divided into four sections. In the first, "American Theory: Democracy, Liberalism, and Rights," Barber addresses issues of ongoing relevance to today's debates about the roots of participatory democracy, including individualism vs. community, the importance of consent, and the irrelevance of Marxism. Essays in the second section, "American Practice: Leadership, Citizenship, and Censorship" provide a "strong democracy" critique of American democratic practice. "Education for Democracy: Civic Education, Service, and Citizenship" applies Barber's theories to three related topics and includes his much-discussed essay "America Skips School." The final section, "Democracy and Technology: Endless Frontier or End of Democracy?" provides glimpses into a future that technology alone cannot secure for democracy. In his preface, Barber writes: "In these essays... I have been hard on my country. Like most ardent democrats, I want more for it than it has achieved, despite the fact that it has achieved more than most people have dared to want." This wide-ranging collection displays not only his passion for democracy, but also his unique perspective on issues of abiding importance for the democratic process. (shrink)

Seeking useful ways to respond to the Covid‐19 pandemic, bioethicists have been tempted to claim for themselves what Alasdair MacIntyre characterized in After Virtue as the moral fiction of managerial expertise. They have been eager to offer a wide range of policy prescriptions, presenting themselves as bureaucratic managers and suggesting an expertise that bioethics may not in fact be able to offer. This was evident, for example, in the petition published by The Hastings Center in March 2020. The pandemic could (...) foster a more hopeful future for bioethics if it were to focus attention less on policy decisions that belong to all citizens and more on some of the most basic moral questions that life presents and with which bioethics has always dealt—including, surely, the virtues needed in order to live well in a time of pandemic. (shrink)

This paper addresses the question of how to educate toward democracy, which has as its defining trait the ability to self-correct. We draw on a study that investigated Deep Reflective Thinking (DRT) as a classroom method for cultivating collective doubt, which is essential for developing students’ capacity for self-correction in a community of inquiry.

One of us [Gilbert, M.. “Collective Belief and Scientific Change.” Sociality and Responsibility. Lanham, MD: Rowman & Littlefield. 37-49.] has proposed that ascriptions of beliefs to scientific communities generally involve a common notion of collective belief described by her in numerous places. A given collective belief involves a joint commitment of the parties, who thereby constitute what Gilbert refers to as a plural subject. Assuming that this interpretive hypothesis is correct, and that some of the belief ascriptions in (...) question are true, then the members of some scientific communities have obligations that may act as barriers both to the generation and, hence, the fair evaluation of new ideas and to changes in their community’s beliefs. We argue that this may help to explain Thomas Kuhn’s observations on “normal science”, and go on to develop the relationship between Gilbert's proposal and several features of a group of physicists working on a fundamental physical theory called “string theory”, as described by physicist Lee Smolin [Smolin, L.. The Trouble with Physics. Mariner Books: New York.]. We argue that the features of the string theory community that Smolin cites are well explained by the hypothesis that the community is a plural subject of belief. (shrink)

It is often said that clinical research and the practice of medicine are fraught with uncertainties. But what do we mean by uncertainty? Where does uncertainty come from? How do we measure uncertainty? Is there a single theory of uncertainty that applies across all scientific domains, including the science and practice of medicine? To answer these questions, we first review the existing theories of uncertainties. We then attempt to bring the enormous literature to bear from other disciplines to address the (...) issue of uncertainty in clinical research and medical practice. Our main and overarching goal is to review and classify uncertainties in clinical medicine. (shrink)

Apology -- Crito -- Phaedo -- Symposium -- Republic.

Place-based education is founded on the idea that the student’s local community is one of their primary learning resources. Place-based education’s underlying educational principle is that students need to first have an experiential understanding of the history, culture, and ecology of the environment in which they are situated before tackling broader national and global issues. Such attempts are a step in the right direction in dealing with controversial issues in a democracy by providing resources for synthesising curriculum though theory (curriculum (...) content, including traditional subjects) and practice (practical learning as experiential education). Nevertheless, many place-based accounts discount Indigenous conceptions of place, which are integral to Indigenous ways of knowing, being and doing, especially in relation to the ontological relationship to Land and Country. Indigenous philosophy has the potential to inform what place-based education means by students developing a ‘sense of place’ when engaging with local communities as their ‘own’ place. In this article we re-imagine the community of inquiry as a place-responsive pedagogy by learning from Indigenous philosophy, and recentring Indigenous notions of place in experiential learning. In addition to exploring the pedagogical potential of a place-responsive account of the community of inquiry, we look to the implications for teacher preparation. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Matter and Spirit in the Age of Animal MagnetismEric G. WilsonDuring the Romantic period, writers on both sides of the Atlantic explored the sleepwalker as a merger of holiness and horror. Emerging when scientific thinkers for the first time were connecting spirit to electricity and magnetism, the somnambulist became to certain Romantics a disclosure of the difficulty of harmonizing unseen and seen, agency and necessity. This problem prominently arose (...) in Anton Mesmer's late eighteenth-century experiments in animal magnetism, in which the sleepwalker proved a paradox: an opaque revelation of transparent currents and an unconscious vehicle of sophisticated thought. Romantics such as Coleridge embraced the somnambulist as an embodiment of these troubles involved in relating motion and meaning. Coleridge and those who responded to him saw in the hypnotized human this sobering possibility: the invisible requires the visible to make itself manifest while the visible needs the invisible to become significant. 1 This is sublime and sinister: to elevate a material form to spiritual power is transcendence; to sink the boundless into a body is grotesque.Here I explore the philosophical implications of animal magnetism, the place of the sleepwalker in the history of ideas, and the role of the hypnotized human in Romantic writers, especially Coleridge. I also meditate on relationships between matter and spirit, machine and human, word and thing. Along the way, I place the history of ideas and the works of Romantic writers in mutually illuminating dialogues. The literary texts shed fresh light on philosophical problems while the ideas reveal hidden literary elements.The somnambulistic trance had been around long before Mesmer's magnetic sleeps. For centuries, shamans had used auto-hypnosis to sound [End Page 329] their souls and other-hypnosis to cure their tribe-members' ailments. However, somnambulism could not become a scientific phenomenon until Europeans in laboratories began to study electricity and magnetism. In the early modern period, Paracelsus argued that a vital fluid courses through the cosmos. The human being draws this flow like a magnet attracts force. When the body pulls to itself evil effluvia, it falls ill. To return patients to health, Paracelsus placed magnets on painful areas. He hoped to extract the unwanted current and return it to the cosmic swirl. 2 In "magnetizing" spirit, Paracelsus opened a door for empirical inquiry into the invisible world. In 1600, William Gilbert claimed that magnets correspond to the earth: both are animated by universal attraction and repulsion. 3 By the end of the seventeenth-century, Newton proposed that things are impelled by a force that draws and repels. Newton's theory of gravity inspired natural philosophers of the next centuries to search for a principle of which the magnet and the spark are manifestations. 4During the second half of the eighteenth century and the early part of the nineteenth, natural philosophers explored electricity and magnetism with unprecedented precision. In 1752, Benjamin Franklin revealed the mystery of lightning and perhaps the spark of life. 5 Inspired by Franklin, F. C. Oetinger, J. L. Fricker, and Prokop Divisch developed a theology of electricity, based on the belief that God is the electrical current. 6 Later in the century, Luigi Galvani and Alessandro Volta debated over whether the galvanic flow might be the origin and principle of life itself. 7 A few years before Franklin harvested lightning, John Michell argued that the magnetic force is not constrained to lodestones but is possibly pervasive. Some years later, Franz Aepinus suggested that magnetism and electricity manifest a deep energy. Soon after, C. A. de Coulomb discovered the mathematical law by which electrical and magnetic forces operate (Whittaker, pp. 50–59).These findings led to the breakthroughs of the nineteenth century. 8 In 1807, Humphry Davy hypothesized that chemical elements interact through electromagnetic affinity or repulsion. 9 In 1820, H. C. Oersted demonstrated the correspondence between electricity and magnetism. The same year, A. M. Ampere formulated the laws by which electrical and magnetic currents interact (Whittaker, pp. 81–86). Michael Faraday in 1831 revealed electromagnetic induction and thus inaugurated a second Copernican revolution: he showed that matter is not solid and discrete but a field of electromagnetic energy. 10 The dreams of [End... (shrink)

This paper inquires the systematical consequences in the Nietzschean critics of the biological determination of life. We proposed an analysis about central topics of this determination: the finalism, the life and chaos. This approach allows us to relieve a systematical conception of what Nietzsche understands by “necessity”. This conception of necessity is not metaphysic in the traditional sense, but implies a subversion of all special metaphysic. Beyond this, it entails a critical to the transcendental and normative version, own of Kantian (...) thought, about the question of life. These confrontations seek to clarify the gnoseological and ontological areas put in check, on the status of the concept of life. (shrink)

One of the leading scholars and academic administrators of his time, Benjamin Jowett was Master of Balliol College as well as Regius Professor of Greek and, for a time, vice-chancellor at Oxford University. Along with his achievements in the area of academic reform, Jowett is remembered for this four-volume translation of Plato's dialogues. Characterising Plato as the 'father of idealism', Jowett reminds readers that while 'he may be illustrated by the writings of moderns … he must be interpreted by (...) his own, and by his place in the history of philosophy'. In this first volume, he includes fourteen early and middle dialogues such as Charmides, Apology, Crito, and Phaedo, each presented with a separate editorial introduction. Jowett's work represents a towering achievement in the field of classical and philosophical studies that had important influence on the subsequent study of Plato. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

Debates over the 'end of art' have tended to obscure Hegel's work on the arts themselves. Benjamin Rutter opens this study with a defence of art's indispensability to Hegel's conception of modernity; he then seeks to reorient discussion toward the distinctive values of painting, poetry, and the novel. Working carefully through Hegel's four lecture series on aesthetics, he identifies the expressive possibilities particular to each medium. Thus, Dutch genre scenes animate the everyday with an appearance of vitality; metaphor frees (...) language from prose; and Goethe's lyrics revive the banal routines of love with imagination and wit. Rutter's important study reconstructs Hegel's view not only of modern art but of modern life and will appeal to philosophers, literary theorists, and art historians alike. (shrink)