Genomic research projects that collect tissues from deceased organ and tissue donors must obtain the authorization of family decision makers under difficult circumstances that may affect the authorization process. Using a quasi-experimental design, the Ethical, Legal, and Social Issues (ELSI) substudy of the Genotype-Tissue Expression (GTEx) project compared the recall and understanding of the donation authorization process of two groups: family members who had authorized donation of tissues to the GTEx project (the comparison group) and family members who had authorized (...) organ and tissue donations in years previous, who subsequently participated in two different mock-authorization processes that mimicked the GTEx authorization process (the intervention groups). Participants in the comparison and intervention groups were matched on key demographic characteristics.We found that participants in the intervention groups who experienced a mock-authorization process demonstrated better recall of the tissue donation request than members of the comparison group. Our data indicate that the stress associated with the loss of a loved one limited the ability of family members to recall details about the GTEx project. However, we found a similar lack of knowledge in both the comparison and the intervention group participants, suggesting lack of knowledge may be due to the complexity and unfamiliarity of the information presented to them during the authorization process. We discuss these findings in the context of everyday clinical decision making in cognitively challenging conditions. (shrink)

Thomas Kuhn had little to say about scientific change in biological science, and biologists are ambivalent about how applicable his framework is for their disciplines. We apply Kuhn’s account of paradigm change to evolutionary microbiology, where key Darwinian tenets are being challenged by two decades of findings from molecular phylogenetics. The chief culprit is lateral gene transfer, which undermines the role of vertical descent and the representation of evolutionary history as a tree of life. To assess Kuhn’s relevance to this (...) controversy, we add a social analysis of the scientists involved to the historical and philosophical debates. We conclude that while Kuhn’s account may capture aspects of the pattern of an episode of scientific change, he has little to say about how the process of generating new understandings is occurring in evolutionary microbiology. Once Kuhn’s application is limited to that of an initial investigative probe into how scientific problem-solving occurs, his disciplinary scope becomes broader. (shrink)

The sizeable theoretical and empirical literature on corporate social responsibility and business ethics in Western, developed economies indicates that the topic has attracted significant interest from academics and practitioners. There is, however, less evidence of the practice of CSR and business ethics in non-Western, transition economies, as insufficient attention is paid to the contextual specifications and underlying processes that may lead to different versions of CSR. Therefore, this paper examines the practice and sense-making of CSR and business ethics from the (...) perspective of the fertile and under researched post-communist context of Central and Eastern Europe, to join the growing academic debate about the impact of cultural and historical traditions on the practice and sense-making of CSR and business ethics in non-Western contexts. The study adopts a particular focus on the post-communist and under researched context of Bulgaria where CSR is still a relatively new phenomenon. By following an exploratory research design and by collecting qualitative data from 34 executives employed by public and private sector organisations in Bulgaria, the study finds that the local business environment is composed of a complex mix of various institutionalised pressures and challenges that predispose organisations to adopt a particular approach to CSR, ethical misconduct and CSR-washing. Apart from the significant contributions related to the practice, understanding and contextualisation of CSR in non-Western countries, the study also identifies challenges of business ethics in transition economies and adds depth to the emerging literature on CSR-washing by proposing a model for neo-communist CSR-washing. The study also offers contributions for practitioners and policy-makers. (shrink)

There is a debate about whether particular properties are for Aristotle non-recurrent and trope-like individuals or recurrent universals. I argue that Physics I.7 provides evidence that he took non-substantial particulars to be neither; they are instead non-recurrent modes. Physics I.7 also helps show why this matters. Particular properties must be individual modes in order for Aristotle to preserve three key philosophical commitments: that objects of ordinary experience are primary substances, that primary substances undergo genuine change, and that primary substances are (...) ontologically fundamental. (shrink)

This statement summarizes the conclusions of the Symposium on the Definition of Death, held at The Catholic University of America in June 2014. After providing the background and context for contemporary debates about brain death and describing the aims of the symposium, the statement notes points of unanimous and broad agreement among the participants, and highlights areas for further study.

Kant’s turn to the subject has changed the epistemological conditions for theology. Four intellectual backgrounds of objections are examined: an Aristotelian and Thomistic teleological order of nature (1); Augustinianism based on original sin in which human agency is completely attributed to God’s grace (2); a Hegelian critique of the deontological conception of an “unconditional ought” which also puts Kant’s postulate of the existence of God into question (3); the combination in Radical Orthodoxy of a postmodern critique of the subject, an (...) Augustinian view of human nature, and a monistic understanding of the Trinity (4). Their different diagnoses why Kant’s work constitutes a cul-de-sac are contrasted with theological positions that welcome it as a watershed: its move from ontology to human subjectivity; from a biologically transmitted inescapable sin to a freedom for good and evil; from a strict reciprocity to an unlimited scope of ethics that is faced with the question of meaning; and from condemning the secular as “heretical” to defining it as the genuine space of the free human counterparts created by God, according to Duns Scotus’s late medieval theology which anticipates Kant’s concept of autonomy. The standard by which theologies are judged is how they do justice to the New Testament’s message of salvation by Jesus Christ. The Conclusion argues that Kant’s turn to freedom in its unconditionality and finitude has opened up a thought form in which the truth of the Gospel finds more adequate categories of understanding than in those of earlier eras. (shrink)

The emerging viewpoint of embodied cognition holds that cognitive processes are deeply rooted in the body's interactions with the world. This position actually houses a number of distinct claims, some of which are more controversial than others. This paper distinguishes and evaluates the following six claims: (1) cognition is situated; (2) cognition is time-pressured; (3) we off-load cognitive work onto the environment; (4) the environment is part of the cognitive system; (5) cognition is for action; (6) off-line cognition is body (...) based. Of these, the first three and the fifth appear to be at least partially true, and their usefulness is best evaluated in terms of the range of their applicability. The fourth claim, I argue, is deeply problematic. The sixth claim has received the least attention in the literature on embodied cognition, but it may in fact be the best documented and most powerful of the six claims. (shrink)

Recent discoveries of geographical patterns in microbial distribution are undermining microbiology’s exclusively ecological explanations of biogeography and their fundamental assumption that ‘everything is everywhere: but the environment selects’. This statement was generally promulgated by Dutch microbiologist Martinus Wilhelm Beijerinck early in the twentieth century and specifically articulated in 1934 by his compatriot, Lourens G. M. Baas Becking. The persistence of this precept throughout twentieth-century microbiology raises a number of issues in relation to its formulation and widespread acceptance. This paper will (...) trace the conceptual history of Beijerinck’s claim that ‘everything is everywhere’ in relation to a more general account of its theoretical, experimental and institutional context. His principle also needs to be situated in relationship to plant and animal biogeography, which, this paper will argue, forms a continuum of thought with microbial biogeography. Finally, a brief overview of the contemporary microbiological research challenging ‘everything is everywhere’ reveals that philosophical issues from Beijerinck’s era of microbiology still provoke intense discussion in twenty-first century investigations of microbial biogeography. (shrink)

Studies of the prevalence and contents of codes of conduct in the private sector show that their use to define an ethical environment or culture, and their effective implementation, must be as part of a learning process that requires inculcation, reinforcement and measurement. Consequently, the public sector must realise it cannot look solely to formal codes to revive and sustain public sector values. Alan Doig is Professor of Public Services Management, and John Wilson is Principal Lecturer and Head of (...) the Centre for Public Services Management, at Liverpool Business School, Liverpool John Moores University. (shrink)

The role of religion in ethical decision-making, both for individual managers and at an organisational level, remains elusive due to contrasting findings in extant literature. This is exacerbated by a dearth of studies focusing on specific religious mechanisms that can foster ethical decision-making, particularly with respect to organisational corporate socially responsible (CSR) behaviour and in backgrounds different from Christianity. This exploratory study investigates the mechanisms in Islam that can influence individual/micro- and organisational/meso-level ethical decision-making, and hence CSR outcomes. It draws (...) on in-depth, qualitative data from 63 domestic organisations in Saudi Arabia, the United Arab Emirates and Oman. The findings reveal a complex macro-normative religious environment, founded on specific factors that shape ethics and decision-making. Internalised by organisational leaders, these factors translate into organisational CSR behaviour as the organisation becomes a place for fulfilling individual religious responsibilities and even creates CSR products shaped around religious principles. The study contributes to the literature on ethical decision-making, organisational behaviour and Islamic CSR and offers recommendations for policymakers and practitioners on integrating religion within the organisation. (shrink)

The book situates the works and reception of the French scholar Pierre de la Ramée (Petrus Ramus) in a variety of European cultural and educational contexts, from Britain and France to Eastern Europe, from Germany to the Iberian peninsula, and from Scandinavia to the Netherlands. Pierre de la Ramée or Petrus Ramus (1515-1572) has long been a controversial figure in educational reform and innovation, from the moment of his first public academic statements in the 1530s, to his reception among scholars (...) in the twentieth and twenty-first centuries. What is beyond dispute, however, is the vast reach of his influence throughout Europe. Ramus's ideas were disseminated through copious editions and translations of his own textbooks, and in wave after wave of adaptations and re-imaginings of his ideas that swept across the continent. This volume embarks on a European tour of Ramism, using a wide range of previously unpublished or untranslated archival evidence from throughout the continent to examine the dissemination of Ramus's works and his intellectual influence in geographic and in disciplinary terms. The ten chapters explore the spread of Ramism from his home country of France to Protestant strongholds in Germany, Holland, and Britain, and in the Catholic context of the Iberian peninsula. The book also examines Ramism in the less familiar territories (to most Anglophone readers) of Scandinavia and Hungary, and considers the preceding and contemporary Dutch and German educational reform movements from which Ramus borrowed to forge his own distinctive intellectual method. (shrink)

Stakeholder theory diverts attention from creating business success to concentrating on who share its fruits. But what right have stakeholders to make the claims they do? Perhaps a new model is needed. T.F.J. Ambler is Grand Metropolitan Senior Research Fellow at London Business School, Sussex Place, Regent's Park, London NW1 4SA, where Andrea Wilson completed her MBA in 1993. She is now a consultant in New York.

So-called “ugly laws” were mostly municipal statutes in the United States that outlawed the appearance in public of people who were, in the words of one of these laws, “diseased, maimed, mutilated, or in any way deformed, so as to be an unsightly or disgusting object” (Chicago City Code 1881). Although the moniker “ugly laws” was coined to refer collectively to such ordinances only in 1975 (Burgdorf and Burgdorf 1975), it has become the primary way to refer to such laws, (...) which targeted the overlapping categories of the poor, the homeless, vagrants, and those with visible disabilities. Enacted and actively enforced between the American Civil War (1867) and World War I (1918), such laws and their enforcement can tell us much about the very sorts of people who were also, a generation later, subject to explicitly eugenic laws, such as sterilization legislation. And like eugenic laws and policies, such laws continue to affect the lives of people with disabilities to this day (Schweik 2011). (shrink)

Concepts of ‘public reason’ vary according to the underlying understandings of theoretical and practical reason; they make a difference to what can be argued for in the public sphere as justified expectations to oneself and fellow-citizens. What is the significance for the scope of ethics when two neo-Kantian theorists of public reason, John Rawls and Jürgen Habermas, propose a reduced reading of the ‘antinomy’ highlighted in Kant’s analysis of practical reason? The desire for meaning, unrelinquishable for humans, is frustrated when (...) moral initiatives are met with hostility. Kant resolves the antinomy between morality and happiness by invoking the concept of a creator God whose concern that our anticipatory moral actions should not fail encourages the hope on which human agency relies. Defining the scope of ethics by the unconditional character of reason rules out the minimisation of ethics to what can safely be expected to be delivered. (shrink)

In three respects, ethics can be marked by the category of the ‘priceless’. Its key reference point, ‘human dignity’, was described by Kant as the exact opposite to what can be priced in equivalents. As an enterprise, ethics is ‘priceless’ as a commitment of the human spirit which goes beyond and against the attitude of success calculation. Yet, an understanding of ethics as unconditional recognition and the anticipatory, asymmetric, innovative praxis (Helmut Peukert) that expresses it have a cost. Where does (...) the motivation to forego, for example, ethically problematic therapies, originate? How can respect for what is priceless be sustained in the face of the relentless spread of market categories diagnosed, among others, by Jürgen Habermas and Paul Ricoeur, against which religions may raise a delaying veto? Only a Christology that can adequately conceptualise the experience of the graciousness and superabundance of God’s gift is able to support the increasingly counter-cultural conviction of something beyond our disposition. (shrink)

In this essay I use Socrates’s aside to Callicles at Gorgias 481c5-482b1 to argue that love is essential to philosophy on Plato’s conception. On my reading, Plato uses the drama of the dialogue to critique the discussion therein, against a standard for philosophy which is implicit in Socrates’s remarks. Plato suggests that Socrates’s exchange with Gorgias is the best of the three, since it best realizes the inseparable goals of pursuing truth and becoming more persuadable by reason. What makes it (...) so is that between Socrates and Gorgias alone does there seem to be a genuine good will and love leading to an effective partnership in the social activity which is philosophy. (shrink)

Can literature help us in a time of crisis? Yes, in many and unexpected ways, as Simone Weil’s literary work shows. Reading Weil’s unfinished tragedy Venice Saved in the context of her poetry, philosophy and politics, we argue that it is an example of literary work that can engender transformation, for three reasons: its presentation and encouragement of attention to beauty; its tragic tension, forcing a deeper vision of the world; and its use of the poetic word. These elements, we (...) conclude, make literature a prime tool for inner and outer transformation, especially when everything seems to be lost. (shrink)

Simone Weil (1909-1943) was one of the foremost French philosophers of the 20th century; a mystic, activist, and writer whose profound work continues to intrigue and inspire today. -/- Mirror of Obedience collects together Weil's poetry and autobiographical writings translated into English for the first time. It offers a rare glimpse into a more personal and introspective Weil than we usually encounter. She was writing and re-working her poems until the end of her life and in a letter from London (...) to her parents, dated 22 January 1943, she expressed the wish for her verses to appear together in print in chronological order, a wish which this volume honours. -/- Weil was a thinker who wrote with discipline and spareness and cherished the poetic form for its power to compress language and distill meaning. In these poems and literary writings, we see her own efforts to craft poems as essential expressions of thought, bringing into view another aspect of Weil's quest for beauty and truth. (shrink)

The Routledge Companion to Philosophy of Physics is a comprehensive and authoritative guide to the state of the art in the philosophy of physics. It contains 54 self-contained chapters written by leading philosophers of physics at both senior and junior levels, making it the most thorough and detailed volume of its type on the market – nearly every major perspective in the field is represented. The Companion’s 54 chapters are organized into 12 sections. The first seven sections cover all of (...) the major physical theories investigated by philosophers of physics today, and the last five explore key themes that unite the study of these theories. I. Classical Mechanics II. Special Relativity III. General Relativity IV. Non-Relativistic Quantum Mechanics V. Quantum Field Theory VI. Quantum Gravity VII. Statistical Mechanics and Thermodynamics VIII. Explanation IX. Intertheoretic Relations X. Symmetries XI. Metaphysics XII. Cosmology. (shrink)

We study whether changes in analyst recommendation ratings systems encouraged by the implementation of NASD 2711 in 2002 are associated with improved objectivity and independence in analyst recommendations. Using recommendations issued during windows surrounding major investment banking events, we show that reductions in analyst optimism following the reforms concentrate in the recommendations of analysts whose employer adopted a three-tier rating system at the time of the reforms, and that this effect is generally stronger for analysts whom the underlying incentives to (...) engage in unethical behaviour is greatest. We also find evidence that adoption of the three-tier system improved the market’s perception of the objectivity of analyst recommendations issued after SEOs, and that for hold and sell-type recommendations this effect was stronger for analysts subject to the greatest potential ethical conflicts. While we find some evidence of a general post-reform increase in the profitability of recommendations issued following equity transactions, this improvement was only conditioned by changes to the rating system in our IPO sample. (shrink)

Ensuring that life-saving antimicrobials remain available as effective treatment options in the face of rapidly rising levels of antimicrobial resistance will require a massive and coordinated global effort. Setting a collective direction for progress is the first step towards aligning global efforts on AMR. This process would be greatly accelerated by adopting a unifying global target — a well-defined global target that unites all countries and sectors. The proposed pandemic instrument — with its focus on prevention, preparedness and response — (...) represents an ideal opportunity to develop and adopt a unifying global target that catalyzes global action on AMR. We propose three key characteristics of a unifying global target for AMR that — if embedded within the pandemic preparedness instrument — could rally public support, funding, and political commitment commensurate with the scale of the AMR challenge. (shrink)

We verified moral distress related to organ shortage for transplantation in nursing students. This quantitative pilot study analyzed data from 104 nursing undergraduate students. Data were collected through a survey composed of four questions and two sociodemographic items. The chi-squared test was used to examine categorical variables, whereas continuous variable data were analyzed using ANOVA and the Pearson Product Moment correlational test for determining the existence of moral distress regarding the availability of one heart for four individuals susceptible to heart (...) transplantation. A high level of moral distress was identified with regard to the hypothetical decision-making process, which justifies the need for further studies on the subject. Given the hypothetical scenario, moral distress was observed among the students, reaching severe distress in some cases. Approval CEP-University of Alberta Pro00068610. (shrink)

Research into the potential associations between tinnitus and cognition has investigated specific cognitive domains in laboratory settings despite adults with tinnitus reporting broad cognitive difficulties in every-day life. To address this limitation, the present study compared performance and perceived exertion on a visual office-like task in 38 adults with tinnitus and 38 adults without tinnitus matched for age, sex and educational background. All participants were also assessed for hearing, anxiety and depression, and participants with tinnitus were also assessed for tinnitus (...) handicap. No associations were found between presence of tinnitus and cognitive performance and perceived exertion on the visual office-like task when corrected for standard and extended high frequency hearing thresholds, anxiety, and depression. The correction for extended high frequency average hearing threshold was significant for performance but not perceived exertion on the visual office-like task. Overall, the results showed extended high frequency hearing, but not tinnitus, was associated with every-day cognitive performance. This indicates clinical testing of hearing thresholds above 8 kHz could support clinicians’ identification and management of cognitive difficulties. One management method suggested by the current findings would include provision of auditory stimulation at frequencies exceeding the frequency response of many current hearing aids. (shrink)