There has been much discussion about what, if any, legal and moral duties professionals have to disclose relevant genetic information to the family members of someone with an identified disease predisposing mutation. Here, we present a case report where dissemination of such a genetic test result did not take place within a family. In contrast to previous literature, there appeared to be no deliberate withholding of information, instead distant relatives were unable to communicate relevant information appropriately. When communication was facilitated (...) through the follow-up of a chance remark, the patient was able to avoid planned major surgery, with its attendant morbidity, and her high anxiety levels were much reduced. We believe this case highlights the need for an ongoing debate on how genetic services can best support patients and their families with disclosing relevant genetic information to other family members. (shrink)

Aims: To describe individuals’ perceptions of the activities that take place within the cancer genetics clinic, the relationships between these activities and how these relationships are sustained. Design: Qualitative interview study. Participants: Forty individuals involved in carrying out cancer genetics research in either a clinical (n = 28) or research-only (n = 12) capacity in the UK. Findings: Interviewees perceive research and clinical practice in the subspecialty of cancer genetics as interdependent. The boundary between research and clinical practice is described (...) as vague or blurred, and this ambiguity is regarded as being sustained by a range of methodological, ethical and economic factors. The implications of these findings for the “therapeutic misconception” are explored. It is argued that while research participation is seen as having therapeutic benefit for individual patients, the interviewees are not labouring under any misconceptions about the relationship between research and clinical care. It is suggested that concepts such as the “therapeutic misconception” may have less relevance in highly technological specialities that are characterised by a developing evidence base. (shrink)

Design: Qualitative interview study. Participants: Fifty-nine patients with a family history of cancer who attend a regional cancer genetics clinic in the UK were interviewed about their current and previous research experiences. Findings: Interviewees gave a range of explanations for research participation. These were categorised as social—research participation benefits the wider society by progressing science and improving treatment for everyone; familial—research participation may improve healthcare and benefit current or future generations of the participant’s family; and personal—research participation provides therapeutic or (...) non-therapeutic benefits for oneself. Conclusions: We discuss the distinction drawn between motives for research participation focused upon self and others, and observe that personal, social and familial motives can be seen as interdependent. For example, research participation that is undertaken to benefit others, particularly relatives, may also offer a number of personal benefits for self, such as enabling participants to feel that they have discharged their social or familial obligations. We argue for the need to move away from simple, static, individualised notions of research participation to a more complex, dynamic and inherently social account. (shrink)

This book provides a focus for future discussion in one of the most important debates within historical theology within the protestant tradition - the debate about the definition of a category of analysis that operates over five centuries of religious faith and practice and in a globalising religion. In March 2009, TIME magazine listed ‘the new Calvinism’ as being among the ‘ten ideas shaping the world.’ In response to this revitalisation of reformation thought, R. Scott Clark and D. G. Hart (...) have proposed a definition of ‘Reformed’ that excludes many of the theologians who have done most to promote this driver of global religious change. In this book, the Clark-Hart proposal becomes the focus of a debate. Matthew Bingham, Chris Caughey, and Crawford Gribben suggest a broader and more historically responsible definition for ‘Reformed,’ as Hart and Scott respond to their arguments. (shrink)

The objective of this study is to describe researchers', health-care providers' and other stakeholders' views of ethical review and research governance procedures. The study design involved qualitative semi-structured interviews. Participants included 60 individuals who either undertook research in the subspecialty of cancer genetics (n = 40) or were involved in biomedical research in other capacities (n = 20), e.g. research governance and oversight, patient support groups or research funding. While all interviewees observed that oversight is necessary to protect research participants, (...) ethical review and research governance (ERG) arrangements were described negatively throughout these interviews. Interviewees identified a number of problems with ERG, including: over-bureaucratization, over-standardization of information requirements for different types of research, a lack of standardization in the types of information required by different committees for the same research and a lack of consistency in different committees' responses. A number of solutions were proposed including streamlining application procedures and harmonizing committees' responses and information requirements. Recent reports suggest that ethical review procedures and research governance arrangements threaten the possibility of undertaking clinical research in the UK, hence the introduction of the Integrated Research Application System (IRAS) is long overdue. However, while IRAS may solve some of the problems identified by interviewees, it remains to be seen to what extent it will impact upon the very negative perceptions of ethics and research governance procedures reported here. (shrink)

Modal conventionalism is the view that two crucial forms of sameness are mind-dependent. There is no phenomenon of sameness in kind, on this view, except in virtue of our conventions for individuating nature’s kinds; there is no phenomenon of numerical sameness across time, for an individual member of some natural kind, except in virtue of our conventions for individuating such members.1 Modal conventionalism has its realist opponents. These opponents have argued, following Kripke’s lead more than thirty years ago (Kripke 1972), (...) that the boundaries of at least many of nature’s kinds are carved out by nature itself, and not by our classifi catory practices (e.g., Millikan 2000: passim, e.g., pp. 25 and 72). But they have not generally argued, with anything approaching the same vigor, that modal conventionalism is wrong in its other main claim. They have not in general argued that the world-given connections among properties, that make those properties mind-independently be membership conditions for some natural kind, at the same time make those properties mind-independently be persistence conditions for the members of the kind—properties the departure of which constitutes a ceasing-to-exist for the object that formerly had them. On the contrary, opponents of modal conventionalism have.. (shrink)

James decides that the best price today on pork chops is at Supermarket S, then James makes driving motions for twenty minutes, then James’ car enters the parking lot at Supermarket S. Common sense supposes that the stages in this sequence may be causally connected, and that the pattern is commonplace: James’ belief (together with his desire for pork chops) causes bodily behavior, and the behavior causes a change in James’ whereabouts. Anyone committed to the idea that beliefs and desires (...) are states installed by evolution must, it seems, think something similar. For how can one see beliefs and desires as conferring selective advantage if not by supposing that, by causing bodily behavior in their subjects, they brought about changes in their subjects’ surroundings? Yet many, many philosophers currently think or worry that mental causation is illusory (see, e.g., Heil and Mele 1993, or Macdonald and Macdonald 1995). Any physical changes which a mental state appears to cause can be viewed as a complex event involving microparticles, and for any such complex event, many philosophers suppose, there will have been previous microphysical occurrences sufficient to cause it. Barring routine overdetermination of such complex events, the apparent causation of mental events seems to be excluded. Nor does it help to say that some salient segment of the previous microphysical event just is the mental event, differently described (Davidson 1970). For describing the previous events as microphysical seems to spotlight the very features in virtue of which they did their causal work; the mental features seem epiphenomenal (Yablo 1992b: pp. 425-36; Yablo 1992a). This paper argues that the complex physical events, which mental events seem excluded from causing, are not caused at all. For they are either accidents, in something like Aristotle’s sense (Sorabji 1980: pp. 3-25), or coincidences, in a sense which David Owens has recently sharpened (Owens 1992). (shrink)

To be a realist about modality, need one claim that more exists than just the various objects and properties that populate the world—e.g. worlds other than the actual one, or maximal consistent sets of propositions? Or does the existence of objects and properties by itself involve the obtaining of necessities (and possibilities) in re? The latter position is now unpopular but not unfamiliar. Aristotle held that objects have essences, and hence necessarily have certain properties. Recently it has been argued that (...) the identity of any property is tied to the natural laws in which it figures, which entails that the occurrence of properties involves the obtaining of nomological necessities ([24], pp. 206-33 and 234-60; [23]; cf. [25] and [6]). Somewhat less recently, Wittgenstein ([28], p. 168) worried that the reality of at least some properties—precise shades of colors being a prime example—involved the obtaining in re of certain impossibilities. This paper argues that Wittgenstein’s worries were right, and not just concerning some properties, but all properties whatever. That there are objects and properties in the world at all, then, amounts to there obtaining modal states of affairs. This argument supplements, rather than replaces, the others. The position on property incompatibility advanced here actually helps defend Aristotelian essentialism against epistemological objections, or so I have argued ([15]). And while this paper’s position on property incompatibility diverges from the idea that a property’s nomic profile is essential to it—more on this in the next section—it is at least compatible with the thought that the necessity involved in the laws of nature enters into ontology at the ground level. (shrink)

More laws obtain in the world,it appears, than just those of microphysics –e.g. laws of genetics, perceptual psychology,economics. This paper assumes there indeedare laws in the special sciences, and notjust scrambled versions of microphysical laws. Yet the objects which obey them are composedwholly of microparticles. How can themicroparticles in such an object lawfully domore than what is required of them by the lawsof microphysics? Are there additional laws formicroparticles – which seems to violate closureof microphysics – or is the ``more'' (...) acoincidental outcome of microphysics itself? This paper argues that the appearance ofviolation is illusory, and the worry aboutcoincidence misleading. We cannot expect tounderstand the special sciences at the level ofthe microparticles. (shrink)

It is widely supposed that, in Hilary Putnam’s phrase, there are no “ready-made objects” (Putnam 1982; cf. Putnam 1981, Ch. 3). Instead the objects we consider real are partly of our own making: we carve them out of the world (or out of experience). The usual reason for supposing this lies in the claim that there are available to us alternative ways of “dividing reality” into objects (to quote the title of Hirsch 1993), ways which would afford us every bit (...) as much practical and cognitive mastery as we now possess. Hence there is no warrant for supposing that the objects recognized by such alternative schemes are any less real than the objects we actually consider real—unless we are to appeal to a “God’s-eye perspective”, which virtually no one wants to do. The reasonable conclusion, many philosophers suppose, is that any system of objects exists only relative to a particular conceptual scheme or system of predicates. Our system of objects is, in this sense, partly of our own making. But this claim should not be heard as a reaffirmation of the idealism of Fichte or Husserl. It is more accurate to take it merely as a claim about sameness and difference among the objects of the world. It is the claim that sameness and difference, whether at the level of kinds or of individual objects, do not obtain mind-independently, but only relative to a conceptual scheme or predicate system (see, e.g., Putnam 1981, pp. 53-54). That is, whether two objects are of the same kind, and whether one and the same individual object now exists at such-and-such.. (shrink)

Deleuze and Guattari develop a notion of “minor literature” in their short book on Kafka, and the opposition major/minor has been used with varying degrees of success by critics working in a range of disciplines including architectural theory. Teasing out the potentially subversive implications of the major/minor opposition requires reading it in relation to other binarisms developed by Deleuze and Guattari in those same years, e.g., state/nomadic science, striated/smooth space, optic/haptic, as well as Guattari’s useful concept “machinic heterogenesis.” Then, one (...) ends up with a minor architecture concerned with partially subversive practices rather than with structure per se. A building’s minor status is figured through its deployment in and production of a space that is a technological, social and political pattern as well as a line of flight. This paper reads minor architecture by examining the minor house built by Henry David Thoreau at Walden Pond and those currently being assembled by the Mad Housers in Atlanta, Georgia. (shrink)

In this study I am going to present and discuss some of the central themes of Gustav Bergmann's theory of perception. I shall be concerned, however, only with "later Bergmann," that is, with the perceptual theory worked out in a series of essays in which Bergmann shifts from phenomenalism to a form of intentional realism. This label ("intentional realism") indicates the two dominant themes in Bergmann's later thought about perception: perceivings are analyzed as mental acts (thoughts) which are intentionally related (...) to real and mind-independent objects and states of affairs. In a timely essay, " Intentionality" (1955) Bergmann presented an impressive defense of mental acts, and although the framework of that essay was still phenomenalistic, the structural analysis of mental acts and their intentionality presented there has not been significantly altered by Bergmann in later writings. In two subsequent essays, "Acts" (1960) and "Realistic Postscript" (1963) his realistic turn was worked out in detail in the context of giving a satisfactory account of ordinary perceptual experience. These three essays will comprise the core texts of the study that follows. (shrink)

The aim of this study is to assess patients' recall of their previous research participation. Recall was established during interviews and compared with entries from clinical notes. Participants were 49 patients who had previously participated in different types of research. Of the 49 patients, 45 (92%) interviewees recalled 69 of 109 (63%) study participations. Level of recall varied according to the type of research, some participants clearly recalled the details of research aims, giving consent and research procedures. Others recalled procedures (...) (e.g. DNA testing) but were unclear about their purpose. There was no significant effect of time on recall. Some types of research participation (e.g. DNA testing) may be recalled as clinical care. We argue that such misunderstandings may have the potential to undermine participants' ongoing consent, particularly in ongoing/longitudinal studies. Valid consent may be best achieved by re-assessing the scope of consent and relating it to the nature of the interventions themselves rather than the reasons for undertaking them. (shrink)

Introduction. The roots of liberal-democratic theory -- Problems of interpretation -- Hobbe : the political obligation of the market. Philosophy and political theory -- Human nature and the state of nature -- Models of society -- Political obligation -- Penetration and limits of Hobbe's political theory -- The Levellers : franchise and freedom. The problem of franchise -- Types of franchise -- The record -- Theoretical implications -- Harrington : the opportunity state. Unexamined ambiguities -- The balance and the gentry (...) -- The bourgeois society -- The equal commonwealth and the equal agrarian -- The self-cancelling balance principle -- Harrington's stature --Locke : the political theory of appropriation. Interpretations -- The theory of property right -- Class differentials in natural rights and rationality -- The ambiguous state of nature -- The ambiguous civil society -- Unsettled problems reconsidered -- Possessive individualism and liberal democracy. The seventeenth-century foundations -- The twentieth-century dilemma -- Appendix : Social classes and franchise classes in England, circa 1648. (shrink)

In _Real Natures and Familiar Objects_ Crawford Elder defends, with qualifications, the ontology of common sense. He argues that we exist -- that no gloss is necessary for the statement "human beings exist" to show that it is true of the world as it really is -- and that we are surrounded by many of the medium-sized objects in which common sense believes. He argues further that these familiar medium-sized objects not only exist, but have essential properties, which we (...) are often able to determine by observation. The starting point of his argument is that ontology should operate under empirical load -- that is, it should give special weight to the objects and properties that we treat as real in our best predictions and explanations of what happens in the world. Elder calls this presumption "mildly controversial" because it entails that arguments are needed for certain widely assumed positions such as "mereological universalism". Elder begins by defending realism about essentialness. He then defends this view of familiar objects against causal exclusion arguments and worries about vagueness. Finally, he argues that many of the objects in which common sense believes really exist, including artifacts and biological devices shaped by natural selection, and that we too exist, as products of natural selection. (shrink)

This seminal work by political philosopher C.B. Macpherson was first published by the Clarendon Press in 1962, and remains of key importance to the study of liberal-democratic theory half-a-century later. In it, Macpherson argues that the chief difficulty of the notion of individualism that underpins classical liberalism lies in what he calls its "possessive quality" - "its conception of the individual as essentially the proprietor of his own person or capacities, owing nothing to society for them." Under such a conception, (...) the essence of humanity becomes freedom from dependence on the wills of others; society is little more than a system of economic relations; and political society becomes a means of safeguarding private property and the system of economic relations rooted in property. As the New Statesman declared: "It is rare for a book to change the intellectual landscape. It is even more unusual for this to happen when the subject is one that has been thoroughly investigated by generations of historians.... Until the appearance of Professor Macpherson's book, it seemed unlikely that anything radically new could be said about so well-worn a topic. The unexpected has happened, and the shock waves are still being absorbed." A new introduction by Frank Cunningham puts the work in a twenty-first-century context. (shrink)

Explores contemporary controversies in bioethics from a Hindu perspective. S. Cromwell Crawford breaks new ground in this provocative study of Hindu bioethics in a Western setting. He provides a new moral and philosophical perspective on fascinating and controversial bioethical issues that are routinely in the news: cloning, genetic engineering, the human genome project, reproductive technologies, the end of life, and many more. This Hindu perspective is particularly noteworthy because of India's own indigenous medical system, which is stronger than ever (...) and drawing continued interest from the West. The Hindu bioethics presented in this book are philosophically pluralistic and ethically contextual, giving them that conceptual flexibility which is often missing in Western religions, but which is demanded by the twenty-first century's complex moral problems. Comprehensive in scope and passionate in nature, Crawford's study is an important resource for analyses of practical ethics, bioethics, and health care. (shrink)

Abstract According to Russellianism, the content of a Russellian thought, in which a person ascribes a monadic property to an object, can be represented as an ordered couple of the object and the property. A consequence of this is that it is not possible for a person to believe that a is F and not to believe b is F, when a=b. Many critics of Russellianism suppose that this is possible and thus that Russellianism is false. Several arguments for this (...) claim are criticized and it is argued that Russellians need not appeal to representational notions in order to defeat them. Contrary to popular opinion, the prospects for a pure Russellianism, a Russellianism without representations, are in fact very good. (shrink)

This paper explores corporate charitable giving disclosures in order to question the extent to which corporations can claim that their philanthropy activities are charitable at all. Exploration of these issues is carried out by means of a tropological analysis that focuses on the different linguistic tropes within the philanthropy disclosures of 52 companies, namely metaphor and synecdoche. The results reveal a number of complex and contradictory things. Primarily, the master metaphor of 'altruism' projected by the corporate disclosures is ideologically at (...) odds with the more business case-oriented discourse that shapes the disclosures. This contradiction is put into starker contrast by the existence of a root metaphor, whereby the recipients of corporate philanthropy are presented as the 'deserving poor'. Synecdochal devices are present within the corporate disclosures, whereby employee initiatives that are independent of corporate strategies are used to confer attributes onto the disclosures that bolster the master metaphor of 'altruism'. As such, corporate philanthropy is presented by the paper as a structurally incoherent discourse and yet one that has implications for both extracting greater value from various societal groups and in defining, on behalf of civil society, what is a worthy cause. (shrink)

This paper explores corporate charitable giving disclosures in order to question the extent to which corporations can claim that their philanthropy activities are charitable at all. Exploration of these issues is carried out by means of a tropological analysis that focuses on the different linguistic tropes within the philanthropy disclosures of 52 companies, namely metaphor and synecdoche. The results reveal a number of complex and contradictory things. Primarily, the master metaphor of ‘altruism’ projected by the corporate disclosures is ideologically at (...) odds with the more business case-oriented discourse that shapes the disclosures. This contradiction is put into starker contrast by the existence of a root metaphor, whereby the recipients of corporate philanthropy are presented as the ‘deserving poor’. Synecdochal devices are present within the corporate disclosures, whereby employee initiatives that are independent of corporate strategies are used to confer attributes onto the disclosures that bolster the master metaphor of ‘altruism’. As such, corporate philanthropy is presented by the paper as a structurally incoherent discourse and yet one that has implications for both extracting greater value from various societal groups and in defining, on behalf of civil society, what is a worthy cause. (shrink)

In _Real Natures and Familiar Objects_ Crawford Elder defends, with qualifications, the ontology of common sense. He argues that we exist -- that no gloss is necessary for the statement "human beings exist" to show that it is true of the world as it really is -- and that we are surrounded by many of the medium-sized objects in which common sense believes. He argues further that these familiar medium-sized objects not only exist, but have essential properties, which we (...) are often able to determine by observation. The starting point of his argument is that ontology should operate under empirical load -- that is, it should give special weight to the objects and properties that we treat as real in our best predictions and explanations of what happens in the world. Elder calls this presumption "mildly controversial" because it entails that arguments are needed for certain widely assumed positions such as "mereological universalism". Elder begins by defending realism about essentialness. He then defends this view of familiar objects against causal exclusion arguments and worries about vagueness. Finally, he argues that many of the objects in which common sense believes really exist, including artifacts and biological devices shaped by natural selection, and that we too exist, as products of natural selection. (shrink)

Most contemporary metaphysicians are sceptical about the reality of familiar objects such as dogs and trees, people and desks, cells and stars. They prefer an ontology of the spatially tiny or temporally tiny. Tiny microparticles 'dog-wise arranged' explain the appearance, they say, that there are dogs; microparticles obeying microphysics collectively cause anything that a baseball appears to cause; temporal stages collectively sustain the illusion of enduring objects that persist across changes. Crawford L. Elder argues that all such attempts to (...) 'explain away' familiar objects project downwards, onto the tiny entities, structures and features of familiar objects themselves. He contends that sceptical metaphysicians are thus employing shadows of familiar objects, while denying that the entities which cast those shadows really exist. He argues that the shadows are indeed really there, because their sources - familiar objects - are mind-independently real. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 33.1 (2000) 96-99 [Access article in PDF] Book Review The Long Path to Nearness: A Contribution to a Corporeal Philosophy of Communication and the Groundwork for an Ethics of Relief The Long Path to Nearness: A Contribution to a Corporeal Philosophy of Communication and the Groundwork for an Ethics of Relief. Ramsey Eric Ramsey. Atlantic Highlands, NJ: Humanities Press, 1998. Pp. xiv + 145. $49.95, cloth. (...) The cryptic title of Ramsey Eric Ramsey's new text creates a very useful metaphor that runs, as a long, sometimes winding, path through the wooded grounds of philosophy, communication, and ethics. The distance of the journey to corporeal communication and an ethics of relief is long in the sense that the journey requires most readers to shed some perceptual baggage as payment for passage. An example of such baggage shedding is Ramsey's effort to "re-call" communication. A valuable section of his work, it elicits an interesting new metaphorical perception of that which we take for granted.The premise that Ramsey works under is an acknowledged one of a critical existential Marxist who is influenced by Martin Heidegger. The additional [End Page 96] frame of this project is Calvin O. Schrag's 1987 book Communication Praxis and the Space of Subjectivity; indeed, Ramsey posits this work as a "building upon" Schrag's contribution. Certainly, in the use and understanding of communicative praxis, Ramsey does extend the work of Schrag. But there is more to Ramsey than new chapters in a story told earlier.Ramsey presents two arguments, along with well-sculpted, carefully detailed supporting premises that make the unfolding an enjoyable process. The issues of The Long Path to Nearness are (1) the neglected body in communication theory, which represents the inescapable contact point with the natural world, and (2) liberation ethics, explicated from an understanding of the absoluteness of uncertainty and the implications of responsibility. The arguments are fashioned around a Heideggerian "being-in-the-world" consciousness, one that, in its essence would presuppose both the body and the other as pretheoretical. Ramsey takes another approach, however, and avoids the transcendental while arguing, in a later context, for the transcendent.The long path begins with a phenomenological explication of the corporeal body, with a frequent and consistent implication of praxis as a sort of journey signpost (50 miles to Dallas... then 40 miles to Dallas, etc.) reminding the reader that practice is essential to the understanding of communication corporeality. In "re-calling" communication, Ramsey defines communication as a dynamic practice that offers possibility, possibility shaped by the binary of active and passive moments. For Ramsey's project, the passive moment is that which represents the material world and the inescapable Dasein that implies the body. Ramsey does not argue for an intercorporeality, choosing instead to imply the concept with a "being-in-the-world-with-other" perspective in the context of the corporeality argument. The active moment is the moment of subjectivity, which represents the consciousness of intentionality. Given Heidegger's definition of logos as "speaking" and Ramsey's professed phenomenological perspective (a study of being as opposed to knowing), possibility for Ramsey represents communication as "being-in-the-world-speaking" through a consciousness of intentionality and a material body presence. This presence in the world is practiced, negotiated, and experienced through communication.Ramsey's argument of possibility is an intricate exploration of the potentiality of horizons that are open-ended, endlessly challenging, and inviting potentiality for an ethics of liberation. Ramsey's explication of possibilities is one of the significant offerings of this effort, and is worth examination on the basis of its nuances and constructions.The overall argument for corporeality will be largely familiar to a European audience immersed in the body politic. This is not to say that the [End Page 97] effort does not offer new and inviting understandings, but rather to suggest that the premises of Ramsey's work best relate to those of continental thought regarding body presence. For those who... (shrink)