Macromolecular protein complexes catalyze essential physiological processes that sustain life. Various interactions between protein subunits could increase the effective mass of certain peptide groups, thereby compartmentalizing protein α-helices. Here, we study the differential effects of applied massive barriers upon the soliton-assisted energy transport within proteins. We demonstrate that excentric barriers, localized onto a single spine in the protein α-helix, reflect or trap three-spine solitons as effectively as concentric barriers with comparable total mass. Furthermore, wider protein solitons, whose energy is (...) lower, require heavier massive barriers for soliton reflection or trapping. Regulation of energy transport, delivery and utilization at protein active sites could thus be achieved through control of the soliton width, or of the effective mass of the protein subunits. (shrink)

Cet article examine la question de l’attention dans son rapport à l’admiration, dont le traitement fait apparaître de profondes divergences entre les Passions de l’âme et l’ Éthique. Dans Les Passions de l’âme, Descartes propose une genèse passionnelle de l’attention, dont la destination gnoséologique est assurée par un acte de la volonté qui transcende les perceptions de l’âme. À l’inverse, dans l’ Éthique, la connaissance ne dépend pas de l’exercice d’une faculté autonome, elle est immanente à l’ordre des idées, ce (...) à quoi l’admiration fait irréductiblement obstacle. La critique spinoziste de l’admiration s’accompagne alors d’une refonte du statut de l’attention et repose sur la critique de la partition cartésienne des facultés de l’âme. Nous montrerons néanmoins que l’attention a une fonction positive sous la forme d’une présence à soi de l’esprit qui veille à l’enchaînement en lui des idées vraies. (shrink)

Suivant le fil directeur du temps, cet ouvrage met au jour la manière dont l'admiration est devenue un problème philosophique central à l'âge classique et examine les différentes conceptions dont elle fait l'objet chez les principaux penseurs de la seconde moitié du XVIIe siècle.

The Bellum ciuile has been the subject of three major editions in the past thirty years, attributable to D.R. Shackleton Bailey, R. Badalì and G. Luck. The existence of these three works highlights the resurgence of sustained interest surrounding Lucan as of the 1970s, with the publication of two significant works, Lucan: An Introduction by F. Ahl and the collective volume of Entretiens à la fondation Hardt, yet it also demonstrates the difficulty in establishing the text of the Pharsalia.

Probing semantic relations Exploration and identification in specialized texts Alain Auger and Caroline Barrière In recent years, several scientific ...

In vitro fertilisation (IVF) daily practice reveals that couples are willing to take greater risks than doctors if there is a higher chance of pregnancy. Arising from this is a frequently addressed issue regarding the embryo transfer strategy: single or double embryo transfer? The dilemma is faced by patients, as well as physicians, who are caught between the possibility of no pregnancies at all and facing the prospect of iatrogenic twin gestation. How could the couple's preferences concerning how many children (...) they would like be taken into account in determining the number of embryos transferred? How should the physician exercise his medical responsibility towards his patients and the unborn child? An effective approach could be to enhance a couple’s autonomy by advocating a medical beneficence that incorporates patients’ values. This can be achieved through a case-by-case approach in a deliberative process of decision-making which includes real patient-centred communication. (shrink)

The essential biological processes that sustain life are catalyzed by protein nano-engines, which maintain living systems in far-from-equilibrium ordered states. To investigate energetic processes in proteins, we have analyzed the system of generalized Davydov equations that govern the quantum dynamics of multiple amide I exciton quanta propagating along the hydrogen-bonded peptide groups in α-helices. Computational simulations have confirmed the generation of moving Davydov solitons by applied pulses of amide I energy for protein α-helices of varying length. The stability and mobility (...) of these solitons depended on the uniformity of dipole-dipole coupling between amide I oscillators, and the isotropy of the exciton-phonon interaction. Davydov solitons were also able to quantum tunnel through massive barriers, or to quantum interfere at collision sites. The results presented here support a nontrivial role of quantum effects in biological systems that lies beyond the mechanistic support of covalent bonds as binding agents of macromolecular structures. Quantum tunneling and interference of Davydov solitons provide catalytically active macromolecular protein complexes with a physical mechanism allowing highly efficient transport, delivery, and utilization of free energy, besides the evolutionary mandate of biological order that supports the existence of such genuine quantum phenomena, and may indeed demarcate the quantum boundaries of life. (shrink)

As the most prominent initiative in the open education movement, the Massive Open Online Course is often claimed to disrupt established educational models through the use of innovative technologies that overcome geographic and economic barriers to higher education. However, this paper suggests that the MOOC project, as a typical example of initiatives in this field, fails to engage with a theory of the subject. As such, uncritical and problematic forms of humanism tend to be assumed in the promotion and (...) delivery of these courses: the expectation of rational and self-directing individuals, with a universal desire for education. This fundamental orthodoxy limits both the understanding of technology and the possibilities for a concept of ‘openness’ in education. Given the global scale of the MOOC, and its high-profile associations with elite universities, the need for critical alternatives is pressing. In this paper I draw on critical posthumanism—an umbrella term for a range of philosophical and theoretical positions—for two purposes. Firstly and principally as a perspective through which to critique the educational reliance on humanism that is maintained in the project of the MOOC, and secondly to suggest alternative frameworks for thinking about the intermingling of humans and technologies in education. Space and time are considered as the two principal sites with which technological change is realised, and the promotion of the MOOC is shown to mask spatial and temporal conditions through adherence to an underlying humanist framework. (shrink)

To select as the subject of a study of limited size a topic as fundamental and, additionally, one so long discussed as has been the case with literary practice greatly risks—and we are fully aware of this—appearing to be an undertaking which is both presumptuous (how many studies, sometimes major ones, have been devoted to this question during recent decades?) and doomed to failure (is it serious to presume, in a few pages, to deal, even partially, with so vast and (...) so complex a subject?). However, one precise reason causes us to think that it is time, today, to re-examine this ancient problem in new terms. The field of French literary research is at present characterized by a major institutional and ideological fact, the massive reality of which certain particular or collective efforts, no matter how remarkable these might be, cannot cover over. An airtight seal continues to separate, globally, traditional literary research from recent studies produced by certain linguists and speech historians in the domain of linguistic practices. Whence this scientifically paradoxical consequence: studies dealing with fundamentally similar objects—discursive practices—are presently being conducted in parallel, on the basis of theoretical premises which are radically opposed in most cases, with each one almost absolutely ignorant of the others. This situation, we believe, is exceedingly harmful to literary research. By making all interdisciplinary relation impossible as well as inhibiting certain questioning necessary within the realm of this research, it contributes to blocking progress in large measure. Need we point out that we nourish no naive hopes of overturning within the space of a few pages a situation whose roots, both institutional and ideological, are so deep? Nor does one distinguish oneself more by providing definitive answers for these basic problems which we propose discussing here, answers which one might even believe possible to guarantee as fully correct. We would only like to attempt to prove, by re-examining in new terms some fundamental problems of literary theory, the advantage which this theory might be able to find in certain data drawn from linguistics and the “analysis of discourse”, and inversely to propose certain theoretical readjustments which a specific reflection on literary practice seems to make necessary in the field of these two disciplines, particularly in that of the second. The pages which follow should, therefore, only be taken for what they are: an attempt, limited in its scope and problematic in its conclusions, to break down some barriers and to open a breach at certain critical points. (shrink)

This paper will, in its successive steps and movements, revolve around one single question, a question that might, at first sight, come across as somewhat irrelevant or even impertinent within the context of philosophical or academic discourse. How romantic is Jean-Luc Nancy? Or: is there a specifically Nancyan sense of romance? Notwithstanding these somewhat unscholarly formulations, I am increasingly convinced that the question of love, or indeed more specifically of romance, is the most intimate inspiration of Nancy’s work, the key (...) unlocking all other keys. The theme of love has always played an important role in his work, from the early essay “Shattered Love” (“L’amour en éclats,” 1986) to his later works on the body and pleasure. In this paper, I will touch upon a number of these texts, but I will more particularly refer to two of Nancy’s more recent works, the yet untranslated book Sexistence from 2017 and Expectation: Philosophy, Literature (2018, published in French in 2015 as Demande: Littérature et philosophie). The question of romance, that is, the question of passionate interaction, of intrigue, of writing, of dramatization. This quite heterogeneous web of associations already implies a number of age-old philosophical issues: the relation between love and thinking; the relation between love and literature; and, subsequently, between philosophy and literature; the issue of the relation itself. The knot uniting these issues under the single heading of “romance” has been most firmly tied about two centuries ago, in the late eighteenth-century movement of early German, i.e., Jena, Romanticism, that significant moment in intellectual history where the barriers between philosophy and literature were broken down and where, quite generally put, the sense of the world was conceived of as a matter of romanticization. Although Nancy himself would be reluctant to call himself a Romantic philosopher in this historical sense of the word, this is exactly what I want to argue here: I want to show that Nancy’s philosophy of love – and by extension his philosophical thinking tout court – should be placed in the tradition of German Romanticism, rather than in that of, for instance, phenomenology, ontology, or philosophy proper. This claim is massive in its depth and scope and can impossibly be explored here in an exhaustive way. Instead, I will flesh out this perspective by advancing four successive hypotheses that enable to mark the contours of what I call Nancy’s romanticism. With this exploration, I hope to do three things at once: firstly, to underscore what I take to be the core or pulse of Nancy’s thinking: the issue of romance; secondly, to investigate to what extent this romantic pulse might be traced back to the Romantic tradition; and, thirdly, to emphasize why Nancy’s romantic thinking is relevant for us today. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Environmental Atrocities and Non-Sentient LifeClaudia Card (bio)Environmental Atrocities and Non-Sentient Life1. To Whom (or to What) Can Evils Be Done?Mention of environmental atrocities calls to mind such catastrophes as major oil spills, which ruin the fishing (not to mention the fish) for extended periods. Such carelessness is not simply a disaster to human projects. It destroys or endangers species and ecosystems as well as individual organisms, plant and animal. (...) It pollutes waters that normally sustain life and interferes with the healthy development of new biotic communities. Not all environmental catastrophes result from of failures of attention. Massive deforestation with agent orange by U.S. armed forces during the war in Viet Nam was no accident.If culpably produced, such catastrophes are moral atrocities—major evils—at least to humans and other animals who suffer horribly or die miserable deaths. Intuitively, I lean toward the even stronger judgment that such culpable omissions and deeds are atrocities also in the sense of evils to a great many kinds of life, including non-sentient nature—plants, [End Page 23] species, biotic communities, and ecosystems. But can that intuition be sustained philosophically?To do so may require showing not only that non-sentient lives suffer but also that they create moral constraints. Some argue, using Kenneth Goodpaster's concept "moral considerability" (what a being has if it should receive direct moral consideration), that even non-sentient beings can constrain us morally in virtue of their having interests that give rise to rights or define a good, a wellbeing, that can be harmed.1 "Interests" here cannot refer, of course, to what the organism cares about. They refer, rather, to what it needs in order to survive, do well, even flourish; what is in the organism's interests is what contributes to its good or wellbeing.Yet thinking about evil has led me to distinguish questions of harm from questions of wrong, that is, of moral constraint. It is not always wrong to cause even extreme harm. In this essay I support the more modest thesis that the idea of "intolerable harm" is no barrier to the idea that environmental atrocities can be evils even to non-sentient life. The question remains whether there are other barriers. Evildoers not only cause intolerable harm but are culpably wrong to do it. To whom must that wrong be done? In concluding I turn briefly to that issue, raising more questions than I can currently answer. Some may be disappointed. Yet the limits of my ambitions in this essay do not make them trivial. For any plausible account of environmental atrocities in a sense that includes evil to non-sentient beings must be able to make sense of the idea of doing such entities intolerable harm and should also indicate something of the range of non-sentient beings so vulnerable and in what ways they are vulnerable. These are my present objectives.In my book The Atrocity Paradigm I develop the theory that evils are reasonably foreseeable intolerable harms produced (or supported, aggravated, maintained, and so on) by culpable wrongdoing.2 Taking atrocities, such as genocide, slavery, and saturation bombings of cities, as paradigm evils, I refer to this view as "the atrocity theory" of evils. It both draws on and mediates between stoic and utilitarian approaches to evil. On my theory, evils have two irreducibly distinct components, wrongdoing and harm, linked by causality. Evil is popularly equated with wickedness or moral turpitude. But on the atrocity theory, the depth of harm to victims, rather than perpetrators' motives, is usually what distinguishes evils from other wrongs.The atrocity theory not only focuses attention more on harm than on [End Page 24] wrongdoing but also directs attention to the grossest harms. Some of the worst damage culpably inflicted by human agents has been to the natural environment. Can such damage be downright evil? In my book I indicated that the atrocity theory was intended to make sense of evils done "to many living beings, not just people or even just sentient beings,"3 although I did not defend that idea or work out the details. The present essay attempts a working out of... (shrink)

Purpose of the study is to determine factors influencing transaction costs on the sharing economy. The article examines the evolution of the fundamental concept of economic theory – transaction costs, under the influence of the expansion of sharing economy. The sharing economy appears to be the result of the further development of the consumption economy, since within the framework of this economic system, the quality of the services provided is improving. The scientific novelty lies in the clarification of the mechanism (...) of mutual development of both the sharing economy and transaction costs. As a result, the importance of the factor of massive use of the Internet and mobile devices by a huge number of people, as influencing the service provision market, was revealed. At the same time, there is no need to overcome various barriers, and entrepreneurs have the opportunity to sell not so much reductions in production costs, but rather a reduction in transaction costs. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Escalation to Academic Extremes?Revisiting Academic Rivalry in the Möhler/Baur DebateGrant Kaplan (bio)INTRODUCTION: THEOLOGY AS THE SITE OF CONFLICTOne way to understand the history of Christian theology is as a history of rivalries. In the Letter to the Galatians, Paul and Peter seem like rivals when Paul recounts "opposing Peter to his face" (Gal. 2:11). The key theological discoveries in the fourth and fifth century are mostly borne of rivalry: (...) Eunomius versus the Cappadocians, and Pelagius versus Augustine. The Middle Ages contain the Eucharistic controversies between Pascasius and Ratramnus, and later controversies about the nature of authority in the theology between Abelard and Lombard. By the sixteenth century, not only the history of theology but the history of the Western churches seems to be intertwined with rivalry, with the Protestant Reformation being the most obvious example. One could also tell the history of religious orders as a history of rivalries between, among others, Franciscans and Dominicans, and later Jesuits. The teachings on justification arose from rivalries, and most of modern Catholic ecclesiology arose from Bellarmine's disputatious interactions with leading Lutherans like Flacius [End Page 163] and Chemnitz. In the past century, much of the theological terrain seems to be shaped by disputes between figures who had once been aligned: Barth and Brunner, Balthasar and Rahner, Cone and Jones.In retrospect, the nineteenth century seemed primed for theological rivalry. Due to social, political, and institutional factors, the nineteenth century was profoundly destabilizing for theology, particularly in Germany, where political realignment threatened to unsettle whatever truce had emerged after the conclusion of the Thirty Years' War in 1648. A number of factors contributed to this climate; perhaps foremost among them was the rapid expansion of academic journals. Without being in the same room, scholars could argue and respond to one another in what must have felt like "real time." Journals, to put it crudely, were the online comment section of their day, and they provided a new medium for theological dispute. Although public debate still figured prominently in the sixteenth century, even as the printing press was making it less central to theological argument, in the nineteenth century, one could escalate debate through asynchronous modes of communication.Both political destabilization and technological innovation made possible a range of intraconfessional disputes: among both Protestants—between mediating and confessing, Kantian and Hegelian, authoritarian, and scientific theologies—and Catholics—between scholastic and modern, German and Roman, Gallican and ultramontanist theologies. These circumstances also occasioned a redoubling of confessional identity. Olaf Blaschke has described the nineteenth century as a "second confessional age."1 By this he means that the nineteenth century, on the scale of confessional identity, looked more like the sixteenth century than the eighteenth did; instead of manifesting an increase in secularizing and nationalizing forces that downplayed religious identities, the nineteenth, according to a variety of measures, witnessed an upsurge in confessional identity.2 This upsurge affected Württemberg, the primarily Protestant territory in the southwestern part of Germany, where Tübingen was located. The newly constituted Württemberg combined a number of tiny, mono-confessional states into a larger, multi-confessional state as part of the reconfigurations brought about by Napoleon. Practically, this meant a loss in political autonomy for Catholic areas within Württemberg.According to one account, the confessional conflicts that memorably marked the 1870s (the Kulturkampf) and also the 1830s and 1840s (the Cologne Troubles and the Kniebeugungsstreiten) were already on the increase in the 1810s in Württemberg, in part due to the massive anniversary celebrations (Wartburgfeier) of the Reformation in 1817.3 This was the same year that the government relocated the newly established Catholic theological faculty from Ellwangen [End Page 164] to Tübingen, a long-time Protestant stronghold with a reputable theological faculty.The Catholic theologians in Tübingen were eager to engage critically with the leading theological issues of the day, resisting the urge to hide behind confessional barriers or pious pretenses. This decision led to a variety of conflicts that could be called rivalrous, and that fall into three categories: The first was within the Catholic faculty itself, as exemplified in the debate over celibacy. Their journal... (shrink)

This book reminds us in yet another context that women's contributions to science can be rendered invisible by “the historical record.” The Manhattan Project, the supersecret midcentury United States research, development, and production enterprise that produced the nuclear bomb, was a massive undertaking, at one time employing 130,000 persons. About 10 percent were women, yet official histories made no mention of female scientists or engineers.Sleuthing by the physicists Ruth Howes and Caroline Herzenberg has documented Manhattan Project contributions by more (...) than three hundred women. Howes and Herzenberg begin with a few well‐known European women pioneers in nuclear science , none Americans and none available for the U.S. bomb effort. They then recount the history of the Manhattan Project via biographical vignettes of women, organized in chapters: “The Physicists,” “The Chemists,” “Mathematicians and Calculators,” “Biologists and Medical Scientists,” “The Technicians,” and “Other Women of the Manhattan Project.”It appears that few of these women knew each other. In her foreword, Ellen Weaver writes: “When I read the personal reminiscences of the men who were nuclear pioneers, I'm struck by the importance they place on their friends and associates, and on the often intense interaction among them, which could lead to major insights in both theory and practice of science. And I'm a bit jealous. By and large, women did not share in that give‐and‐take.”Not only was there little networking among women scientists and technicians in the early 1940s while the bomb was being developed, but there was little opportunity for them to share their experiences later. Only a very small percentage of these women were able to continue their professional careers. The many barriers to women as professional scientists and engineers, temporarily lowered owing to the manpower shortages of wartime, were raised after the war. There did not develop a community of women, engaged in teaching and research, with roots in the Manhattan Project.A web page is being developed to gather and provide further information about the women scientific workers of the Manhattan Project. Howes and Herzenberg are setting up an on‐line archive there, hoping that others who have information about the women scientific workers of the Manhattan Project will contact them via the web page or by email .The magnitude of their endeavor to learn about these women was illustrated vividly to me while writing this review. I attended the memorial service for my aunt, Mary Matilda Morrison Pendleton , and heard in her eulogy that “she worked as a nurse at the Hanford project, near Richland, Washington, where the government was secretly making atomic bombs. She would work shift work, two weeks of day shift, two weeks of swing shift, two weeks of graveyard shift, then she would get seven days off. She wore a badge every day that was checked after each day's work to see how much she had been radiated.” Although I thought that I knew her well, my aunt's role in the Manhattan Project had been unknown to me.The women of the Manhattan Project are finally gaining visibility. For example, Nancy Cook Steeper's book‐length biography of Dorothy Scarritt McKibbon is being published by the Los Alamos Historical Society. Howes and Herzenberg have provided ideas and starting points for many additional biographical projects. Perhaps the greatest long‐term value of their book is the impetus that it will give to further research.The book is well written, easy to read, and attractively printed. An appendix, listing the women and their roles, and a thorough index combine to make this an easily used reference work. There is also an informative sixteen‐page chronology that focuses on the crucial period from 1938 through 1945. (shrink)

Barriers is Linguistic Inquiry Monograph 13.

This essay introduces the massive redeployment hypothesis, an account of the functional organization of the brain that centrally features the fact that brain areas are typically employed to support numerous functions. The central contribution of the essay is to outline a middle course between strict localization on the one hand, and holism on the other, in such a way as to account for the supporting data on both sides of the argument. The massive redeployment hypothesis is supported by (...) case studies of redeployment, and compared and contrasted with other theories of the localization of function. (shrink)

The formulation and proof of Hume’s Law and several related inference barrier theses.

What are the elements from which the human mind is composed? What structures make up our _cognitive architecture?_ One of the most recent and intriguing answers to this question comes from the newly emerging interdisciplinary field of evolutionary psychology. Evolutionary psychologists defend a _massively modular_ conception of mental architecture which views the mind –including those parts responsible for such ‘central processes’ as belief revision and reasoning— as composed largely or perhaps even entirely of innate, special-purpose computational mechanisms or ‘modules’ that (...) have been shaped by natural selection to handle the sorts of recurrent information processing problems that confronted our hunter-gatherer forebears (Cosmides and Tooby,192; Sperber, 1994; Samuels, 1998a). (shrink)

Implication barrier theses deny that one can derive sentences of one type from sentences of another. Hume’s Law is an implication barrier thesis; it denies that one can derive an ‘ought’ (a normative sentence) from an ‘is’ (a descriptive sentence). Though Hume’s Law is controversial, some barrier theses are philosophical platitudes; in his Lectures on Logical Atomism, Bertrand Russell claims: You can never arrive at a general proposition by inference particular propositions alone. You will always have to (...) have at least one general proposition in your premises. (Russell, 1918, p. 206) We will refer to this claim—that one cannot derive general sentences from particular sentences—as Russell’s Law.1 A third barrier thesis claims that one cannot derive sentences about the future from sentences about the past or present. Hume’s endorsement of this barrier thesis is well-known: all inferences from experience suppose, as their foundation, that the future will resemble the past . . . if there be any suspicion that the course of nature may change, and that the past may be no rule for the future, all experience becomes useless, and can give rise to no inference or conclusion. It is impossible, therefore, that any argument from experience can prove this resemblance of the past to the future; since all these arguments are founded on the supposition of that resemblance. (Hume, EHU 4.21/37) We will refer to this barrier thesis as Hume’s Second Law. A fourth barrier thesis says that one cannot derive a necessary sentence from one about the actual world and we will refer to this last thesis Kant’s Law. Such implication barrier theses present a problem. (shrink)

Contemporary realities of global population movement increasingly bring to the fore the challenge of quality and equitable health provision across language barriers. While this linguistic challenge is not unique to immigration contexts and is likewise shared by health systems responding to the needs of aboriginal peoples and other historical linguistic minorities, the expanding multilingual landscape of receiving societies renders this challenge even more critical, owing to limited or even non‐existing familiarity of modern and often monolingual health systems with the particular (...) needs of new linguistic minorities. The centrality of language to health beliefs, attitudes, practices, cultural scripts, and conceptual frameworks emphasizes its pivotal role in the healthcare process, and consequently in the adverse effects of treatment that is language‐insensitive and unaware. Such an attitude on the part of medical authorities risks considerable epistemic injustice in the form of a (mis)judgement of patients’ intelligence, credibility, and rationality based on the language that they speak and the manner in which they speak it, consequently impacting the quality and equity of care provided. This danger, I argue, may be effectively countered by fostering among the participants in the healthcare process a sense of epistemic humility through greater metalinguistic awareness. Outlining a range of operative steps that can be used to facilitate this. I argue that the reality of language barriers in the healthcare process, while not entirely eliminable, may nevertheless be successfully addressed, in order to mitigate the challenge of quality and equitable healthcare provision in multilingual societies. (shrink)

Hospitals in many countries have had clinical ethics committees for over 20 years. Despite this, there has been little research to evaluate these committees and growing evidence that they are underutilized. To address this gap, we investigated the question ‘What are the barriers and facilitators nurses and physicians perceive in consulting their hospital ethics committee?’ Thirty-four nurses, 10 nurse managers and 31 physicians working at four Canadian hospitals were interviewed using a semi-structured interview guide as part of a larger investigation. (...) We used content analysis of the interview data related to barriers and facilitators to use of hospital ethics committees to identify nine categories of barriers and nine categories of facilitators. These categories as well as their subcategories are discussed and those specific to nurses or physicians are identified. The need to increase health professionals' use of clinical ethics committees through reducing barriers and maximizing facilitators is discussed. (shrink)

This study inspected the effect of Massive Open Online Course and flipped instruction on EFL learners’ foreign language speaking anxiety, foreign language learning motivation, and attitude toward English learning. To fulfill this objective, the Oxford Quick Placement Test was given to 160 Iranian EFL learners, of whom 120 upper-intermediate participants were chosen and divided into two experimental groups—MOOC and flipped —and one control group. After that, all selected participants were administered a speaking anxiety questionnaire and a motivation questionnaire as (...) the pre-test of the research. Then, one of the experimental groups received an online-based instruction via Skype: one conversation was instructed to this group online every session. The other experimental group received the treatment via flipped-based instruction. The audio files and the texts of the conversations were sent to this group via the WhatsApp application because they all had easy access to it. On the other hand, the control group did not receive any Internet-delivered treatment yet was trained through a face-to-face method. This process continued until the last session, and after the treatment period, the post-tests of speaking anxiety and motivation were given to all three groups to determine the effectiveness of the treatment. Moreover, two attitude questionnaires were administered to the experimental groups to examine their attitudes toward the MOOC and the flipped models of instructions. The findings of the One-way ANOVA test, Post-hoc Scheffe test, and paired samples t-test showed that there were significant differences between the post-test of the experimental groups and the control group. The results indicated that the experimental groups significantly outflanked the control group after the treatment. Lastly, the outcomes showed that participants in both experimental groups had positive attitudes toward technological-based instructional environments. (shrink)

Achieving the global benefits of artificial intelligence (AI) will require international cooperation on many areas of governance and ethical standards, while allowing for diverse cultural perspectives and priorities. There are many barriers to achieving this at present, including mistrust between cultures, and more practical challenges of coordinating across different locations. This paper focuses particularly on barriers to cooperation between Europe and North America on the one hand and East Asia on the other, as regions which currently have an outsized impact (...) on the development of AI ethics and governance. We suggest that there is reason to be optimistic about achieving greater cross-cultural cooperation on AI ethics and governance. We argue that misunderstandings between cultures and regions play a more important role in undermining cross-cultural trust, relative to fundamental disagreements, than is often supposed. Even where fundamental differences exist, these may not necessarily prevent productive cross-cultural cooperation, for two reasons: (1) cooperation does not require achieving agreement on principles and standards for all areas of AI; and (2) it is sometimes possible to reach agreement on practical issues despite disagreement on more abstract values or principles. We believe that academia has a key role to play in promoting cross-cultural cooperation on AI ethics and governance, by building greater mutual understanding, and clarifying where different forms of agreement will be both necessary and possible. We make a number of recommendations for practical steps and initiatives, including translation and multilingual publication of key documents, researcher exchange programmes, and development of research agendas on cross-cultural topics. (shrink)

In The Architecture of the Mind, Carruthers proposes a new and detailed explanation for how human cognition could be both flexible and massively modular. The combinatorial nature of our linguistic faculty and our capacity to engage in inner speech are the cornerstones of this new explanation. Despite the ingenuity of this proposal, I argue that Carruthers has failed to explain how a massively modular mind could display the flexibility that is characteristic of human thought.

In Paradigms and Barriers Howard Margolis offers an innovative interpretation of Thomas S. Kuhn's landmark idea of "paradigm shifts," applying insights from cognitive psychology to the history and philosophy of science. Building upon the arguments in his acclaimed Patterns, Thinking, and Cognition, Margolis suggests that the breaking down of particular habits of mind—of critical "barriers"—is key to understanding the processes through which one model or concept is supplanted by another. Margolis focuses on those revolutionary paradigm shifts— such as the switch (...) from a Ptolemaic to a Copernican worldview—where challenges to entrenched habits of mind are marked by incomprehension or indifference to a new paradigm. Margolis argues that the critical problem for a revolutionary shift in thinking lies in the robustness of the habits of mind that reject the new ideas, relative to the habits of mind that accept the new ideas. Margolis applies his theory to famous cases in the history of science, offering detailed explanations for the transition from Ptolemaic to cosmological astronomy, the emergence of probability, the overthrow of phlogiston, and the emergence of the central role of experiment in the seventeenth century. He in turn uses these historical examples to address larger issues, especially the nature of belief formation and contemporary debates about the nature of science and the evolution of scientific ideas. Howard Margolis is a professor in the Harris Graduate School of Public Policy Studies and in the College at the University of Chicago. He is the author of Selfishness, Altruism, and Rationality and Patterns, Thinking, and Cognition, both published by the University of Chicago Press. (shrink)

Cognitive modules are internal mental structures. Some theorists and empirical researchers hypothesise that the human mind is either partially or massively comprised of structures that are modular in nature. Is the massive modularity of mind hypothesis a cogent view about the ontological nature of human mind or is it, rather, an effective/ineffective adaptationist discovery heuristic for generating predictively successful hypotheses about both heretofore unknown psychological traits and unknown properties of already identified psychological traits? Considering the inadequacies of the case (...) in favour of massive modularity as an ontological hypothesis, I suggest approaching and valuing massive modularity as an adaptationist discovery heuristic. (shrink)

This essay introduces the massive redeployment hypothesis, an account of the functional organization of the brain that centrally features the fact that brain areas are typically employed to support numerous functions. The central contribution of the essay is to outline a middle course between strict localization on the one hand, and holism on the other, in such a way as to account for the supporting data on both sides of the argument. The massive redeployment hypothesis is supported by (...) case studies of redeployment, and compared and contrasted with other theories of the localization of function. (shrink)

Quartz (2002) argues that some recent findings about the evolution of the brain (Finlay & Darlington, 1995) are inconsistent with evolutionary psychologists’ massive modularity hypothesis. In substance, Quartz contends that since the volume of the neocortex evolved in a concerted manner, natural selection did not act on neocortical systems independently of each other, which is a necessary condition for the massive modularity of our cognition to be true. I argue however that Quartz’s argument fails to undermine the (...) class='Hi'>massive modularity hypothesis. (shrink)

I argue that the present (if not insuperable) lack of fixed standards in philosophy is associated with three barriers to philosophical progress, pertaining to intra-disciplinary siloing, sociological rather than philosophical determinants of philosophical attention, and the encouraging of bias.

A fundamental task for any prospective cognitive architecture is information control: routing information to the relevant mechanisms to support a variety of tasks. Jerry Fodor has argued that the Massive Modularity Hypothesis cannot account for flexible information control due to its architectural commitments and its reliance on heuristic information processing. I argue instead that the real trouble lies in its commitment to nativism—recent massive modularity models, despite incorporating mechanisms for learning and self-organization, still cannot learn to control information (...) flexibly enough. After defending this position, I close the paper by discussing wider implications for control and cognitive architecture. (shrink)

In spite of its success, Neo-Darwinism is faced with major conceptual barriers to further progress, deriving directly from its metaphysical foundations. Most importantly, neo-Darwinism fails to recognize a fundamental cause of evolutionary change, “niche construction”. This failure restricts the generality of evolutionary theory, and introduces inaccuracies. It also hinders the integration of evolutionary biology with neighbouring disciplines, including ecosystem ecology, developmental biology, and the human sciences. Ecology is forced to become a divided discipline, developmental biology is stubbornly difficult to reconcile (...) with evolutionary theory, and the majority of biologists and social scientists are still unhappy with evolutionary accounts of human behaviour. The incorporation of niche construction as both a cause and a product of evolution removes these disciplinary boundaries while greatly generalizing the explanatory power of evolutionary theory. (shrink)

Abstract: The massive redeployment hypothesis (MRH) is a theory about the functional topography of the human brain, offering a middle course between strict localization on the one hand, and holism on the other. Central to MRH is the claim that cognitive evolution proceeded in a way analogous to component reuse in software engineering, whereby existing components-originally developed to serve some specific purpose-were used for new purposes and combined to support new capacities, without disrupting their participation in existing programs. If (...) the evolution of cognition was indeed driven by such exaptation, then we should be able to make some specific empirical predictions regarding the resulting functional topography of the brain. This essay discusses three such predictions, and some of the evidence supporting them. Then, using this account as a background, the essay considers the implications of these findings for an account of the functional integration of cognitive operations. For instance, MRH suggests that in order to determine the functional role of a given brain area it is necessary to consider its participation across multiple task categories, and not just focus on one, as has been the typical practice in cognitive neuroscience. This change of methodology will motivate (even perhaps necessitate) the development of a new, domain-neutral vocabulary for characterizing the contribution of individual brain areas to larger functional complexes, and direct particular attention to the question of how these various area roles are integrated and coordinated to result in the observed cognitive effect. Finally, the details of the mix of cognitive functions a given area supports should tell us something interesting not just about the likely computational role of that area, but about the nature of and relations between the cognitive functions themselves. For instance, growing evidence of the role of “motor” areas like M1, SMA and PMC in language processing, and of “language” areas like Broca’s area in motor control, offers the possibility for significantly reconceptualizing the nature both of language and of motor control. (shrink)

Background Speaking up to safeguard patients is a crucial ethical and moral obligation for nurses, but it is also a difficult and potentially dangerous component of nursing work. Health advocacy is gaining impetus in the medical literature, despite being hampered by barriers resulting in many nurses in Ghana remaining mute when faced with advocacy-required situations. We explored situations that thwart nurses from performing their health advocacy role. Research question What would cause nurses to take no action when they witness situations (...) that require them to act as health advocates for their clients or communities? Research Design An inductive, descriptive qualitative design was used to collect and analyse data on barriers that prevent nurses from practising their health advocacy role in Ghana. Individual one-on-one in-depth interviews were conducted using a semi-structured interview guide. The data were analysed using qualitative content analysis. Participants and research context Twenty-four professional nurses and midwives registered with the Nursing and Midwifery Council were recruited from three regional hospitals in Ghana. These public hospitals were chosen from the upper, middle and coastal regions. Ethical considerations The UKZN Ethics Review Committee in South Africa and the GHS Ethics Review Committee in Ghana both gave their approval for this study. Findings Intrapersonal barriers, interpersonal barriers, and structural barriers emerged as major obstacles that nurses experience when performing their health advocacy role. Conclusions Barriers to health advocacy have undermined nurses' ability to function as health advocates and are preventing them from utilising their health advocacy position in nursing practise. Giving nursing students positive role models in the classroom and in the clinic can help them become more effective health advocates. (shrink)

This paper presents results from the analysis of business school dean responses to a survey designed to determine how sustainability, including sustainable business practices and climate change content, is being incorporated into business school curriculum. Information is also gathered on how schools and colleges of business are preparing instructors to incorporate sustainability-related content into their courses, the preferred programmatic approaches for offering content to students, and the barriers that impede modification of current curriculum to incorporate sustainability. It concludes with a (...) discussion of research that colleges and schools of business might conduct as part of their strategy to better understand how to bring their curriculum into alignment with new student demands for these topics. Background information on higher education commitment to sustainability is provided. (shrink)

The philosophy of patient-centred care has become widely embraced but its implementation is dependent on interrelated factors. A factor that has received limited attention is the role of policy tools. In Ontario, one method government can use to promote healthcare priorities is through health regulatory colleges, which set the standard of practice for health professionals. The degree to which government policy in support of patient-centered care has influenced the direction provided by health regulatory colleges to their members, and ultimately impacted (...) actual patient care, remains unclear. This study investigates the extent to which Ontario’s health regulatory colleges have provided explicit written guidance to members related to the importance of patient-centred care. It also explores applied and theoretical explanations that may further our understanding of why patient-centred care has not been more fully embraced. Findings reveal that guidance provided by Ontario’s health regulatory colleges varies widely. Institutional barriers and the choice of policy tools for disseminating government preferences may hinder full implementation of the principles of patient-centred care. More fully understanding the role health regulatory colleges’ play in facilitating the implementation of health policy will contribute positively to dialogue and to efforts to achieve positive health system reforms. (shrink)

Biologists seems to hold two fundamental beliefs: Organisms are organized into levels and the individuals at these levels differ in their properties. Together these suggest that there will be massive multiple realization, i.e. that many human psychological properties are multiply realized at many neurobiological levels. This paper provides some documentation in support of this suggestion.

This dissertation focuses on the massive modularity hypothesis defended by evolutionary psychologists---the hypothesis that the human mind is composed largely or perhaps even entirely of special purpose information processing organs or "modulees" that have been shaped by natural selection to handle the sorts of recurrent information processing problems that confronted our hunter-gatherer forebears. ;In discussing MMH, I have three central goals. First, I aim to clarify the hypothesis and develop theoretically useful notions of "module" and "domain-specificity" that can play (...) the roles required of them by evolutionary psychology. Second, I aim to evaluate the plausibility MMH in the light of the broad range of arguments that have been developed and defended in the literature. I argue that all the main, general arguments both for and against MMH are unsatisfactory. Moreover, I suggest that if the case for MMH is to be made, it will only result from the successive accumulation of specific, empirical evidence for the existence of particular modules. ;Finally, I address a range of issues that arise from evolutionary psychological approaches to reasoning and rationality. Much of what evolutionary psychologists have said about human reasoning is in response to a widely discussed "pessimistic" interpretation that has been developed and defended by Kahneman, Tversky and their followers. According to this view, human beings are prone to systematic deviations from appropriate norms of rationality because they lack the underlying competence to handle a wide array of reasoning tasks. Evolutionary psychologists appear to reject this pessimistic interpretation in favor of the view that we possess a wide range of reasoning modules that employ rational rules of inference. I argue, however, that there is no genuine disagreement between evolutionary psychologists and their opponents over the extent to which human beings are rational. I also discuss the distinction between competence efforts and performance efforts. Although this distinction has played a central role in recent discussions of human rationality, I argue that if MMH is true, then we face insurmountable problems in trying to draw the performance error/competence error distinction. (shrink)

One of the controversial issues in the development of Heidegger’s thought is the problem of the will. Th e communis opinio is that Heidegger embraced the concept of the will in a non-critical manner at the beginning of the thirties and , in particular, he employed it in his political speeches of 1933–1934. Jacques Derrida for instance speaks about a “massive voluntarism” in relation to Heidegger’s thought in this period. Also Brett Davis discerns a period of “existential voluntarism” in (...) 1930–1934, in which Heidegger takes over a notion of the will in a non-critical manner. In this article, this interpretation is challenged and a stronger interpretation of Heidegger’s concern with the will is developed. Our hypothesis is that Heidegger’s concern with the will at the onset of the thirties is brought about by his confrontation (Auseinandersetzung) with the concept of the will. Based on his lecture courses from 1930 and 1936/37 and his Rectoral Address from 1933, enables us to discern three main characteristics of Heidegger’s destructed concept of the will in the early thirties. (shrink)