Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
relations had become apparent. Against this (...) background we outline how a range of scientific developments and conceptual considerations can be regarded as enabling and perhaps necessitating contemporary systems approaches. We suggest that philosophical ideas have a valuable part to play in making sense of complex scientific and disciplinary issues. (shrink)

Synthetic biology is an increasingly high-profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA-based device construction, genome-driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into (...) two broader issues that define synthetic biology: the relationships between biology and engineering, and between synthesis and analysis. These themes also illuminate synthetic biology's connections to genetic and other forms of biological engineering, as well as to systems biology. We suggest that all these knowledge-making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems. (shrink)

Understanding how scientific activities use naming stories to achieve disciplinary status is important not only for insight into the past, but for evaluating current claims that new disciplines are emerging. In order to gain a historical understanding of how new disciplines develop in relation to these baptismal narratives, we compare two recently formed disciplines, systems biology and genomics, with two earlier related life sciences, genetics and molecular biology. These four disciplines span the twentieth century, a period in which the processes (...) of disciplinary demarcation fundamentally changed from those characteristic of the nineteenth century. We outline how the establishment of each discipline relies upon an interplay of factors that include paradigmatic achievements, technological innovation, and social formations. Our focus, however, is the baptism stories that give the new discipline a founding narrative and articulate core problems, general approaches and constitutive methods. The highly plastic process of achieving disciplinary identity is further marked by the openness of disciplinary definition, tension between technological possibilities and the ways in which scientific issues are conceived and approached, synthesis of reductive and integrative strategies, and complex social interactions. The importance – albeit highly variable – of naming stories in these four cases indicates the scope for future studies that focus on failed disciplines or competing names. Further attention to disciplinary histories could, we suggest, give us richer insight into scientific development. (shrink)

Synthetic biology is an increasingly high‐profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA‐based device construction, genome‐driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into (...) two broader issues that define synthetic biology: the relationships between biology and engineering, and between synthesis and analysis. These themes also illuminate synthetic biology's connections to genetic and other forms of biological engineering, as well as to systems biology. We suggest that all these knowledge‐making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems. BioEssays 30:57–65, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

In this thesis I examine a number of topics that bear on explanation and understanding in molecular and cell biology, in order to shed new light on explanatory practice in those areas and to find novel angles from which to approach relevant philosophical debates. The topics I look at include mechanism, emergence, cellular complexity, and the informational role of the genome. I develop a perspective that stresses the intimacy of the relations between ontology and epistemology. Whether a phenomenon looks mechanistic, (...) or complex, or indeed emergent, is largely an epistemic matter, yet has an objective basis in features of the world. After reviewing several concepts of mechanism I consider the influential recent account of Machamer, Darden and Craver (MDC). That account makes interesting proposals concerning the relationship between mechanistic explanation and intelligibility, which are consistent with the results of the investigation I undertake into the science surrounding protein folding. In relation to a number of other issues pertaining to biological systems I conclude that the MDC account is insufficiently nuanced, however, leading me to outline an alternative approach to mechanism. This emphasizes the importance of structure—function relations and addresses issues raised by reflection on the nature of cellular complexity. These include the distinction between structure and process and the different possible bases on which system organization may be maintained. The account I give of emergence construes the phenomenon in terms of psychological deficit: phenomena are emergent when we lack the capacity to trace through and model their causal structures using our cognitive schemas. I conclude by developing these ideas into a preliminary and partial account of explanation and understanding. This aspires to cover the significant fraction of work in molecular and cell biology that correlates biological structures, processes and functions by visualizing phenomena and making them imaginable. (shrink)

Alexander Moritzi is one of the most obscure figures in the early history of evolutionary thought. Best known for authoring a flora of Switzerland, Moritzi also published Réflexions sur l’espèce en histoire naturelle, a remarkable book about evolution with an overtly materialist viewpoint. In this work, Moritzi argues that the generally accepted line between species and varieties is artificial, that varieties can over time give rise to new species, and that deep time and turnover of species in the fossil (...) record clearly support an evolutionary interpretation of biological diversity. Moritzi was also a gradualist and viewed relationships between taxa as best represented by a ramifying tree. Although Réflexions was the first full book to be written on the topic of evolution following Lamarck’s Philosophie zoologique, Moritzi’s evolutionist contribution was stillborn, read by almost no one in his lifetime and ultimately absent from the many historiographies of evolutionary thought. This is unfortunate since many of the arguments Moritzi marshaled on behalf of an evolutionary explanation of life can be found in subsequent transmutationist writings by Frédéric Gérard, Robert Chambers, Henri Lecoq, Baden Powell, Charles Naudin, Herbert Spencer, Alfred Russel Wallace, and Charles Darwin—none of whom is likely to have ever known of the existence of Réflexions. Finally, Moritzi’s arguments, along with those found in Darwin’s private essay on evolution of the same year, provide an excellent window into the state of evolutionary thought and debate over the nature of species at the beginning of the 1840s. (shrink)

John Alexander entered the Powell Street branch of the San Francisco Savings Bank shortly after 2:00 p.m. yesterday. He took his place in line and quietly waited his turn. But when he reached the window of teller Jane East, he quickly took a pistol from his pocket and began to order her to give him all the money in her cash drawer. Just as Alexander started to make his demand, Barney Gleason, a bank customer, rushed up to (...) East’s window, shoved Alexander to the side, and simultaneously knocked Alexander’s pistol to the floor. Bob Mann, the guard on duty, saw the gun, quickly scooped it up, and turned the tables on Alexander, who was soon handcuffed and taken off by the police. James Metzger, the bank manager, warmly thanked Gleason and said he would recommend him for a “San Francisco Certificate of Merit.” These certificates are awarded monthly to citizens who risk their lives for their fellow San Franciscans. (shrink)

Do the sciences aim to uncover the structure of nature, or are they ultimately a practical means of controlling our environment? In Instrumental Biology, or the Disunity of Science, Alexander Rosenberg argues that while physics and chemistry can develop laws that reveal the structure of natural phenomena, biology is fated to be a practical, instrumental discipline. Because of the complexity produced by natural selection, and because of the limits on human cognition, scientists are prevented from uncovering the basic structure (...) of biological phenomena. Consequently, biology and all of the disciplines that rest upon it--psychology and the other human sciences--must aim at most to provide practical tools for coping with the natural world rather than a complete theoretical understanding of it. (shrink)

Neither art nor philosophy was kind to beauty during the twentieth century. Much modern art disdains beauty, and many philosophers deeply suspect that beauty merely paints over or distracts us from horrors. Intellectuals consigned the passions of beauty to the margins, replacing them with the anemic and rarefied alternative, "aesthetic pleasure." In Only a Promise of Happiness, Alexander Nehamas reclaims beauty from its critics. He seeks to restore its place in art, to reestablish the connections among art, beauty, and (...) desire, and to show that the values of art, independently of their moral worth, are equally crucial to the rest of life.Nehamas makes his case with characteristic grace, sensitivity, and philosophical depth, supporting his arguments with searching studies of art and literature, high and low, from Thomas Mann's Death in Venice and Manet's Olympia to television. Throughout, the discussion of artworks is generously illustrated.Beauty, Nehamas concludes, may depend on appearance, but this does not make it superficial. The perception of beauty manifests a hope that life would be better if the object of beauty were part of it. This hope can shape and direct our lives for better or worse. We may discover misery in pursuit of beauty, or find that beauty offers no more than a tantalizing promise of happiness. But if beauty is always dangerous, it is also a pressing human concern that we must seek to understand, and not suppress. (shrink)

For much of its history, philosophy was not merely a theoretical discipline but a way of life, an "art of living." This practical aspect of philosophy has been much less dominant in modernity than it was in ancient Greece and Rome, when philosophers of all stripes kept returning to Socrates as a model for living. The idea of philosophy as an art of living has survived in the works of such major modern authors as Montaigne, Nietzsche, and Foucault. Each of (...) these writers has used philosophical discussion as a means of establishing what a person is and how a worthwhile life is to be lived. In this wide-ranging, brilliantly written account, Alexander Nehamas provides an incisive reevaluation of Socrates' place in the Western philosophical tradition and shows the importance of Socrates for Montaigne, Nietzsche, and Foucault. Why does each of these philosophers—each fundamentally concerned with his own originality—return to Socrates as a model? The answer lies in the irony that characterizes the Socrates we know from the Platonic dialogues. Socratic irony creates a mask that prevents a view of what lies behind. How Socrates led the life he did, what enabled or inspired him, is never made evident. No tenets are proposed. Socrates remains a silent and ambiguous character, forcing readers to come to their own conclusions about the art of life. This, Nehamas shows, is what allowed Montaigne, Nietzsche, and Foucault to return to Socrates as a model without thereby compelling them to imitate him. This highly readable, erudite study argues for the importance of the tradition within Western philosophy that is best described as "the art of living" and casts Montaigne, Nietzsche, and Foucault as the three major modern representatives of this tradition. Full of original ideas and challenging associations, this work will offer new ways of thinking about the philosophers Nehamas discusses and about the discipline of philosophy itself. (shrink)

This is an expanded and thoroughly revised edition of the widely adopted introduction to the philosophical foundations of the human sciences. Ranging from cultural anthropology to mathematical economics, Alexander Rosenberg leads the reader through behaviorism, naturalism, interpretativism about human action, and macrosocial scientific perspectives, illuminating the motivation and strategy of each.Rewritten throughout to increase accessibility, this new edition retains the remarkable achievement of revealing the social sciences’ enduring relation to the fundamental problems of philosophy. It includes new discussions of (...) positivism, European philosophy of history, causation, statistical laws, quantitative models, and postempiricist social science, along with a completely updated literature guide that keys chapters to widely anthologized papers. (shrink)

' But, although such a being (a purely intellectual being) might perhaps be conceived to exist, and although, in studying our internal frame, ...

Alexander R. Pruss examines a large family of paradoxes to do with infinity - ranging from deterministic supertasks to infinite lotteries and decision theory. Having identified their common structure, Pruss considers at length how these paradoxes can be resolved by embracing causal finitism.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

The aim of interpretation is to capture the past in the future: to capture, not to recapture, first, because the iterative prefix suggests that meaning, which was once manifest, must now be found again. But the postulated author dispenses with this assumption. Literary texts are produced by very complicated actions, while the significance of even our simplest acts is often far from clear. Parts of the meaning of a text may become clear only because of developments occurring long after its (...) composition. And though the fact that an author means something may be equivalent to the fact that a writer could have meant it, this is not to say that the writer did, on whatever level, actually mean it.Alexander Nehamas, professor of philosophy at the University of Pittsburgh, has written articles on ancient Greek philosophy, literary theory, Nietzsche and Thomas Mann. (shrink)

New York City hospitals expanded resources to an unprecedented extent in response to the COVID pandemic. Thousands of beds, ICU beds, staff members, and ventilators were rapidly incorporated into h...

Many philosophers invoke the "wisdom of nature" in arguing for varying degrees of caution in the development and use of genetic enhancement technologies. Because they view natural selection as akin to a master engineer that creates functionally and morally optimal design, these authors tend to regard genetic intervention with suspicion. In Part II, we examine and ultimately reject the evolutionary assumptions that underlie the master engineer analogy (MEA). By highlighting the constraints on ordinary unassisted evolution, we show how intentional genetic (...) modification can overcome many of the natural impediments to the human good. Our contention is that genetic engineering offers a solution that is more eff icient, reliable, versatile, and morally palatable than the lumbering juggernaut of Darwinian evolution. In Part III, we evaluate a recent attempt to ground precautionary enhancement heuristics in adaptive etiology. Our problem with this approach is two-fold: first, it is based on the same "strong adaptationist" interpretation of evolution that motivates the flawed MEA, and second, the etiological concept of function on which it relies provides indirect and potentially misleading information about the likely consequences of genetic intervention. We offer instead enhancement criteria based on causal relationships in ontogeny. We conclude that rather than grounding a presumption against deliberate genetic modification, the causal structure of the living world gives us good moral reason to pursue it. (shrink)

I show that Armstrong’s view of laws as second-order contingent relations of ‘necessitation’ among categorical properties faces a dilemma. The necessitation relation confers a relation of extensional inclusion (‘constant conjunction’) on its relata. It does so either necessarily or contingently. If necessarily, it is not a categorical relation (in the relevant sense). If contingently, then an explanation is required of how it confers extensional inclusion. That explanation will need to appeal to a third-order relation between necessitation and extensional inclusion. The (...) same dilemma reappears at this level. Either Armstrong must concede that some properties are not categorical but have essential powers – or he is faced with a regress. (shrink)

Alexander's views on universals are, it seems, quite important in the history of western philosophy. When Boethius gives in his second commentary on Porphyry's Isagoge his solution to the problem of universals as he conceived it, he claims to be adopting Alexander's approach. If true, this means that the locus classicus for all western medieval thinkers on this topic is really a rendering of Alexander's teaching. Alexander commented Aristotle’s statement in his On the Soul “The universal (...) animal either is nothing at all or is posterior if it exists”, and this commentary has been translated into Arabic several times in the classical period. In this study the anonymous Arabic translations of Alexander’s commentary has been translated into English. (shrink)

Stephen Jay Gould argued that replaying the “tape of life” would result in a radically different evolutionary outcome. Some biologists and philosophers, however, have pointed to convergent evolution as evidence for robust replicability in macroevolution. These authors interpret homoplasy, or the independent origination of similar biological forms, as evidence for the power of natural selection to guide form toward certain morphological attractors, notwithstanding the diversionary tendencies of drift and the constraints of phylogenetic inertia. In this paper, I consider the implications (...) of homoplasy for the debate over the nature of macroevolution. I argue that once the concepts of contingency and convergence are fleshed out, it becomes clear that many instances of homoplasy fail to negate Gould’s overarching thesis, and may in fact support a Gouldian view of life. My argument rests on the distinction between parallelism and convergence, which I defend against a recent challenge from developmental biology. I conclude that despite the difficulties in defining and identifying parallelism, the concept remains useful and relevant to the contingency controversy insofar as it underscores the common developmental origins of iterated evolution. (shrink)

I argue that the naturalism of Thomas Kuhn's "The Structure of Scientific Revolutions," which he himself later ignored, is worthy of rehabilitation. A naturalistic conception of paradigms is ripe for development with the tools of cognitive science. As a consequence a naturalistic understanding of world-change and incommensurability is also viable.

In this paper I ask how educational researchers can believe the subjective perceptions of qualitative participant-observers given the concern for objectivity and generalisability of experimental research in the behavioural and social sciences. I critique the most common answer to this question within the educational research community, which posits the existence of two (or more) equally legitimate epistemological paradigms—positivism and constructivism—and offer an alternative that places a priority in educational research on understanding the purposes and meanings humans attribute to educational practices. (...) Only within the context of what I call a transcendent view from somewhere—higher ideals that govern human activities—can we make sense of quantitative as well as qualitative research findings. (shrink)

This book presents new findings that deal with different facets of the well-being of children and their relevance to the proper treatment of children. The well-being of children is considered against the background of a wide variety of legal, political, medical, educational and familial perspectives. The book addresses diverse issues from a range of disciplinary perspectives using a variety of methods. It has three major sections with the essays in each section loosely organized about a common general theme. The first (...) section focuses on issues concerning the relation between children’s well-being and autonomy or agency. The second section deals with child well-being insofar as the limits of parental authority are concerned. The third section has a more applied orientation and addresses a variety of public policy controversies involving the interpretation of children’s well-being. (shrink)

Despite its centrality and its familiarity, W. V. Quine's dispute with Rudolf Carnap over the analytic/synthetic distinction has lacked a satisfactory analysis. The impasse is usually explained either by judging that Quine's arguments are in reality quite weak, or by concluding instead that Carnap was incapable of appreciating their strength. This is unsatisfactory, as is the fact that on these readings it is usually unclear why Quine's own position is not subject to some of the very same arguments. A satisfying (...) and surprising account is here presented that stiches together the puzzling pieces of this important philosophical exchange and that in turn leads to an explanation of why it is so difficult to say whether anything of substance is at stake. (shrink)

Training in the responsible conduct of research (RCR) is required for many research trainees nationwide, but little is known about its effectiveness. For a preliminary assessment of the effectiveness of a short-term course in RCR, medical students participating in an NIH-funded summer research program at the University of California, San Diego (UCSD) were surveyed using an instrument developed through focus group discussions. In the summer of 2003, surveys were administered before and after a short-term RCR course, as well as to (...) alumni of the courses given in the summers of 2002 and 2001. Survey responses were analyzed in the areas of knowledge, ethical decision-making skills, attitudes about responsible conduct of research, and frequency of discussions about RCR outside of class. The only statistically significant improvement associated with the course was an increase in knowledge, while there was a non-significant tendency toward improvements in ethical decision-making skills and attitudes about the importance of RCR training. The nominal impact of a short-term training course should not be surprising, but it does raise the possibility that other options for delivering information only, such as an Internet-based tutorial, might be considered as comparable alternatives when longer courses are not possible. (shrink)

Journal of Business Ethicsrecently published a critique of ethical practices in quantitative research by Zyphur and Pierides (J Bus Ethics 143:1–16, 2017). The authors argued that quantitative research prevents researchers from addressing urgent problems facing humanity today, such as poverty, racial inequality, and climate change. I offer comments and observations on the authors’ critique. I agree with the authors in many areas of philosophy, ethics, and social research, while making suggestions for clarification and development. Interpreting the paper through the pragmatism (...) of William James, I suggest that the authors’ arguments are unlikely to change attitudes in traditional quantitative research, though they may point the way to a new worldview, or Jamesian “sub-world,” in social research. (shrink)

Beauty, or at least natural beauty, is famously a symbol of the morally good in Kant's theory of taste. Natural beauty is also, we argue, a symbol of the systematicity of nature. This symbolic connection of beauty and systematicity in nature sheds light on the relation between the principles underlying the use of reflecting judgement. The connection also motivates a more general interpretive proposal: the fact that the imagination can symbolize ideas plays a crucial role in the theory of taste; (...) it is the mechanism that underlies pure judgements of taste, the operation by which the imagination ‘schematizes without a concept’. (shrink)

In this volume his object is to fully examine his friend's writings and characters and draws upon his own personal recollections to do so.

I argue that the naturalism of Thomas Kuhn’s The Structure of Scientific Revolutions, which he himself later ignored, is worthy of rehabilitation. A naturalistic conception of paradigms is ripe for development with the tools of cognitive science. As a consequence a naturalistic understanding of world-change and incommensurability is also viable.

In my 'Dispositions and Antidotes', The Philosophical Quarterly, 48 (1998), I raise an objection to the conditional analysis of dispositions, both in its simple formulation and in a more sophisticated version due to David Lewis, The Philosophical Quarterly, 47 (1997). The objection suggests that a disposition may be continuously present and the appropriate stimulus occur without the manifestation occurring, because some outside influence, an antidote, interferes. Gundersen in The Philosophical Quarterly, 50 (2000), argues that my objection rests on an equivocation (...) about which object possesses the disposition and more particularly on an equivocation about the context in which the events referred to take place, and that when the equivocation is resolved the counter-example disappears. I respond by showing that the counter-example does remain if we take contextual and mereological issues into account, and I conclude by remarking that the difference with Lewisdepends on whether certain features are seen as significant for the semanticsand metaphysics of dispositions or as merely characteristic of the pragmaticsof common usage. (shrink)

Paul Horwich has argued that Kripke's Wittgenstein's 'sceptical challenge' to the notion of meaning and rule-following only gets going if an 'inflationary' conception of truth is presupposed, and he develops a 'use-theoretic' conception of meaning which he claims is immune to Kripke's Wittgenstein's sceptical attack. I argue that even if we grant Horwich his 'deflationary' conception of truth, that is not enough to undermine Kripke's Wittgenstein's sceptical argument. Moreover, Horwich's own 'use-theoretic' account of meaning actually falls prey to that sceptical (...) challenge. (publisher). (shrink)

Paul Horwich has argued that Kripke's Wittgenstein's 'sceptical challenge' to the notion of meaning and rule-following only gets going if an 'inflationary' conception of truth is presupposed, and he develops a 'use-theoretic' conception of meaning which he claims is immune to Kripke's Wittgenstein's sceptical attack. I argue that even if we grant Horwich his 'deflationary' conception of truth, that is not enough to undermine Kripke's Wittgenstein's sceptical argument. Moreover, Horwich's own 'use-theoretic' account of meaning actually falls prey to that sceptical (...) challenge. (publisher). (shrink)

During the early modern period, a framework broadly attributable to Descartes sought to establish all knowledge on a foundation of indubitable truths that are fully clear and totally certain: intuitions. A powerful challenge to treating these seemingly unassailable intuitions as epistemic foundations is that the only truths which can be known in this fashion are so obvious and useless that they could not produce any other knowledge. Rationalists typically respond to this worry by maintaining that there are substantive intuitive truths. (...) Other natural options are to maintain that tautologous truths can serve as a fit foundation, or to reject this framework entirely. Empiricists like Locke, Hume, Condillac, and Mill opt for these other solutions. While Locke and Hume offer views that revise and refine this framework, Condillac and Mill engage in more radical departures from it. An interesting result of this difference in approach is that we see Locke and Hume subdividing reason between two domains – one in which intuition reigns, and one which is more properly the domain of the senses – while in Condillac and Mill we see two differing approaches – analysis and induction, respectively – to unifying all human reasoning within a single domain. (shrink)

Paul Boghossian has recently argued against reductive dispositionalism concerning mental content. However, there is a powerful version of reductive dispositionalism—based on work by Ramsey and Lewis—that Boghossian does not consider. In this paper I argue that Boghossian's arguments can be adapted to apply even to this stronger version of reductionism.

The subtraction argument aims to show that there is an empty world, in the sense of a possible world with no concrete objects. The argument has been endorsed by several philosophers. I show that there are currently two versions of the argument around, and that only one of them is valid. I then sketch the main problem for the valid version of the argument.

SENSATIONALISM 1 1. Introductory 1 2. Mach's Sensationalism 4 3. Developments of Sensationalism 22 II. THE INHERENT WEAKNESS OF SEN- SATIONALISM 25 1. The Point of Sensationalism 25 2. The Ambiguity of 'Sensation' 27 3. The Fundamental Conflict 35 4. Mistakes, Incorrigibility and Simplicity 40 III. DESCRIPTION 51 1. Describing and Descriptions 51 2. Describing in Terms of Sensations 67 IV. THE POSSIBILITY OF 'PURE' DES- CRIPTIONS 79 V. SCIENTIFIC PROBLEMS 99 VI. DESCRIPTIONS AND EXPLANATIONS 111 BIBLIOGRAPHY 142 INDEX 145 (...) -/- -v- . (shrink)

In my ‘Dispositions and Antidotes’, The Philosophical Quarterly, 48, I raise an objection to the conditional analysis of dispositions, both in its simple formulation and in a more sophisticated version due to David Lewis, The Philosophical Quarterly, 47. The objection suggests that a disposition may be continuously present and the appropriate stimulus occur without the manifestation occurring, because some outside influence, an antidote, interferes. Gundersen in The Philosophical Quarterly, 50, argues that my objection rests on an equivocation about which object (...) possesses the disposition and more particularly on an equivocation about the context in which the events referred to take place, and that when the equivocation is resolved the counter‐example disappears. I respond by showing that the counter‐example does remain if we take contextual and mereological issues into account, and I conclude by remarking that the difference with Lewisdepends on whether certain features are seen as significant for the semanticsand metaphysics of dispositions or as merely characteristic of the pragmaticsof common usage. (shrink)

Alexander Altmann's acclaimed, wide-ranging biography of Moses Mendelssohn (1729-96) was first published in 1973, but its stature as the definitive biography remains unquestioned. In fact, there has been no subsequent attempt at an intellectual biography of this towering and unusual figure: no other Jew so deeply rooted in the Jewish tradition was at the same time so much a part of the intellectual life of the German Enlightenment in the second half of the eighteenth century. As such, Moses Mendelssohn (...) came to be recognized as the inaugurator of a new phase in Jewish history; all modern Jews today are in his debt. Altmann presents Moses Mendelssohn in strictly biographical terms. He does not attempt to assess his significance with the hindsight of historical perspective nor to trace his image in subsequent generations, but rather to observe his life from the period within which it was set. Altmann has written an absorbing and compelling narrative that makes a whole epoch come alive with great drama, for Mendelssohn's life was a kaleidoscope of the European intellectual scene, Jewish and non-Jewish. As both a prominent philosopher and a believing Jew, Mendelssohn became a spokesman for the Jews and Judaism; he was one of the rare figures who become the symbol of an era. Through Altmann's skilful use of hitherto unpublished archival material, the reader is introduced to the vast array of people-men of letters, artists, politicians, scientists, philosophers, and theologians-with whom Mendelssohn was in contact, and sometimes in conflict. What was Mendelssohn's Judaism like? To what extent did the disparate worlds of Judaism and modern Enlightenment jostle each other in his mind and to what degree could he harmonize them? These questions are not easily answered, and it is only in the aggregate of a multitude of accounts of experiences, reaction, and statements on his part that the answer is to be found. Alexander Altmann's analysis of this wealth of material is extraordinary in its discernment, subtlety, and clarity of expression. This masterly work will be of interest not only to those who are concerned with Jewish intellectual history but also to those interested in eighteenth-century cultural and social history, philosophy and theology, literary criticism, aesthetics, and the other areas of intellectual activity in ferment at that time. The general reader will also find much of contemporary relevance in Mendelssohn's life, not only because of his exemplary devotion to reason and tolerance, but also because of his lifelong struggle with the basic dilemma of the Jew in the modern world: the attraction of assimilation versus the singularity of Jewish life, and the preservation of Jewish identity versus integration in the wider society. (shrink)