As crucial interface organs gut and skin have much in common. Therefore it is unsurprising that several gut pathologies have skin co‐morbidities. Nevertheless, the reason for this remains ill explored, and neither mainstream gastroenterology nor dermatology research have systematically investigated the ‘gut‐skin axis'. Here, in reviewing the field, we propose several mechanistic levels on which gut and skin may interact under physiological and pathological circumstances. We focus on the gut microbiota, with its huge metabolic capacity, and the role of dietary (...) components as potential principle actors along the gut‐skin axis. We suggest that metabolites from either the diet or the microbiota are skin accessible. After defining open key questions around the nature of these metabolites, how they are sensed, and which cutaneous changes they can induce, we propose that understanding of these pathways will lead to novel therapeutic strategies based on targeting one organ to improve the health of the other. (shrink)

Introduction: Platonic dramatology -- The political and philosophical problems. Using pre-Socratic philosophy to support political reform: the Athenian stranger ; Plato's Parmenides: Parmenides' critique of Socrates and Plato's critique of Parmenides ; Becoming Socrates ; Socrates interrogates his contemporaries about the noble and good -- Paradigms of philosophy. Socrates' positive teaching ; Timaeus-Critias: completing or challenging Socratic political philosophy? ; Socratic practice -- The trial and death of Socrates. The limits of human intelligence ; The Eleatic challenge ; The trial (...) and death of Socrates -- Conclusion: Why Plato made Socrates his hero. (shrink)

This important text introduces students to both feminism and other social and political theories via an examination of the inter-relationship between different feminist positions and key contemporary debates. The book takes each debate in turn, outlines the main themes, discusses different feminist responses and evaluates the implications for real-life political and social issues. This user-friendly structure effectively redraws the map of contemporary feminist thought, offering a fresh and succinct summary of an extensive range of material and graphically demonstrating the ongoing (...) relevance and value of a feminist perspective. (shrink)

Truth is standardly considered a requirement on epistemic acceptability. But science and philosophy deploy models, idealizations and thought experiments that prescind from truth to achieve other cognitive ends. I argue that such felicitous falsehoods function as cognitively useful fictions. They are cognitively useful because they exemplify and afford epistemic access to features they share with the relevant facts. They are falsehoods in that they diverge from the facts. Nonetheless, they are true enough to serve their epistemic purposes. Theories that contain (...) them have testable consequences, hence are factually defeasible. (shrink)

Psychologists and philosophers have argued that the capacity for perseverance or “grit” depends both on willpower and on a kind of epistemic resilience. But can a form of hopefulness in one’s future success also constitute a source of grit? I argue that substantial practical hopefulness, as a hope to bring about a desired outcome through exercises of one’s agency, can serve as a distinctive ground for the capacity for perseverance. Gritty agents’ “practical hope” centrally involves an attention-fuelled, risk-inclined weighting of (...) two competing concerns over action: when facing the decision of whether to persevere, hopeful gritty agents prioritize the aim of choosing a course of action which might go very well over that of choosing a course of action which is very likely to go fairly well. By relying on the notion of a “risk-inclined attentional pattern” as a dimension of gritty agents’ practical hope, we can explain that form of hope’s contribution to their motivation and practical rationality, especially on a risk-weighted expected utility framework. The upshot is a more pluralistic view of the sources of grit. (shrink)

I defend the thesis that friendship can constitutively require epistemic irrationality against a recent, forceful challenge, raised by proponents of moral and pragmatic encroachment. Defenders of the “encroachment strategy” argue that exemplary friends who are especially slow to believe that their friends have acted wrongly are simply sensitive to the high prudential or moral costs of falsely believing in their friends’ guilt. Drawing on psychological work on epistemic motivation (and in particular on the notion of “need for closure”), I propose (...) a different picture of what friendship requires in the doxastic realm. I argue that contrary to what the encroachment strategy suggests, exemplary friends’ belief formation ought not be guided by a concern with accuracy or error avoidance, but instead by a need to avoid a “specific closure” – namely, a need to avoid concluding in their friends’ guilt. I propose that exemplary friendship often generates a defeasible, doxastic obligation to exemplify such a need, despite its inherent corrupting effects on exemplary friends’ epistemic faculties. (shrink)

Is it possible to apply a theoretical approach to ethics? The French philosopher Catherine Chalier addresses this question with an unusual combination of traditional ethics and continental philosophy. In a powerful argument for the necessity of moral reflection, Chalier counters the notion that morality can be derived from theoretical knowledge. Chalier analyzes the positions of two great moral philosophers, Kant and Levinas. While both are critical of an ethics founded on knowledge, their criticisms spring from distinctly different points of (...) view. Chalier reexamines their conclusions, pitting Levinas against (and with) Kant, to interrogate the very foundations of moral philosophy and moral imperatives. She provides a clear, systematic comparison of their positions on essential ideas such as free will, happiness, freedom, and evil. Although based on a close and elegant presentation of Kant and Levinas, Chalier's book serves as a context for the development of the author's own reflections on the question "What am I supposed to do?" and its continued importance for contemporary philosophy. (shrink)

Counterpath is a collaborative work by Catherine Malabou and Jacques Derrida that answers to the gamble inherent in the idea of “travelling with” the philosopher of deconstruction. Malabou's readerly text of quotations and commentary demonstrates how Derrida's work, while appearing to be anything but a travelogue, is nevertheless replete with references to geographical and topographical locations, and functions as a kind of counter-Odyssey through meaning, theorizing, and thematizing notions of arrival, drifting, derivation, and catastrophe. In fact, by going straight (...) to the heart of the Derridean idea of “spacing,” she finally makes it seem as though Derrida has never written about anything but travel. Malabou's text is punctuated by a series of postcards received by Derrida from destinations such as Istanbul and Porto, Laguna Beach and Athens, which are inspired by his reading of her evolving discussion. Writing in a familiar and unguarded manner, as if he were “on vacation” from his own writing, Derrida still remains totally faithful to that work and invites the reader to reflect on much of what haunts his texts as well as his daily life, questions of distance and death, the relation to the other, and exile. (shrink)

Pursuing difficult long-term goals typically involves encountering substantial evidence of possible future failure. If decisions to pursue such goals are serious only if one believes that one will act as one has decided, then some of our lives’ most important decisions seem to require belief against the evidence. This is the puzzle of difficult action, to which I offer a solution. I argue that serious decisions to φ do not have to give rise to a belief that one will φ, (...) but can instead be accompanied by a hope to φ. Hope can motivate and rationalize the various actions that we associate with serious commitment. It can also account for the existence of special pressures to adopt an agential stance toward one’s future. Because hope can be cognitively rational when belief is not, there is no problematic tension between the ideal of epistemic rationality and the phenomenon of difficult action. (shrink)

Comment la philosophie de Hegel pourrait-elle encore promettre quelque chose puisqu'elle est apparue, aux yeux des lecteurs contemporains, comme une entreprise d'annulation du temps? Le savoir absolu n'est-il pas le resultat du processus dialectique par lequel l'esprit releve toute temporalite et par la toute surprise, l'evenement se produisant toujours trop tard? D'une absence de pensee de l'avenir dans la philosophie de Hegel decoulerait une absence d'avenir de la philosophie hegelienne elle-meme. C'est contre une telle assertion que le present ouvrage s'inscrit (...) en faux; il se propose pour cela de travailler le concept de plasticite, montrant comment il forme en profondeur, a la fois comme sa structure et comme son rythme, le contenu speculatif. Est plastique ce qui est susceptible de recevoir comme de donner la forme, mais aussi de l'aneantir. Hegel degage ce concept de son sol natal, l'art, pour le rendre a sa veritable origine : le developpement de la subjectivite. Est dit plastique, en effet, le rapport que la subjectivite entretient avec l'accident, avec ce qui arrive. L'auto-determination apparait comme proces de temporalisation au sein duquel la subjectivite, dans l'attitude contrastee d'un voir venir, se donne et par la recoit sa propre forme, anticipant son avenir tout en renoncant a en maitriser l'irruption. La plasticite du concept hegelien de temps est le foyer de resistance clandestin ou se prepare la reponse a l'accusation de vulgarite portee par Heidegger a l'encontre de ce meme concept. (shrink)

The question of when and how the basic concepts that characterize modern science arose in Western Europe has long been central to the history of science. This book examines the transition from Renaissance engineering and philosophy of nature to classical mechanics oriented on the central concept of velocity. For this new edition, the authors include a new discussion of the doctrine of proportions, an analysis of the role of traditional statics in the construction of Descartes' impact rules, and go deeper (...) into the debate between Descartes and Hobbes on the explanation of refraction. They also provide significant new material on the early development of Galileo's work on mechanics and the law of fall. (shrink)

After defining plasticity in terms of its active embodiments, Malabou applies the notion to the work of Hegel, Heidegger, Levinas, Levi-Strauss, Freud, and ...

But in this book, Catherine Malabou proposes a more radical meaning for plasticity, one that not only adapts itself to existing circumstances, but forms a ...

This chapter contains sections titled: Religion Spirituality Education.

In November 1996, Catherine Clément and Julia Kristeva began a correspondence exploring the subject of the sacred. In this collection of those letters Catherine Clément approaches the topic from an anthropologist's point of view while Julia Kristeva responds from a psychoanalytic perspective. Their correspondence leads them to a controversial and fundamental question: is there anything sacred that can at the same time be considered strictly feminine? The two voices of the book work in tandem, fleshing out ideas and (...) blending together into a melody of experience. The result is a dialogue that delves into the mysteries of belief -- the relationship between faith and sexuality, the body and the senses -- which, Clément and Kristeva argue, women feel with special intensity. Although their discourse is not necessarily about theology, the authors consider the role of women and femininity in the religions of the world, from Christianity and Judaism to Confucianism and African animism. They are the first to admit that what they have undertaken is "as impossible to accomplish as it is fascinating." Nevertheless, their wide-ranging and exhilarating dialogue succeeds in raising questions that are perhaps more important to ask than to answer. (shrink)

In _African Somaesthetics: Cultures, Feminisms, Politics_, Catherine F. Botha brings together original research on the body in African cultures, interrogating the possible contribution of a somaesthetic approach in the context of colonization, decolonization, and globalization in Africa.

Ethics for Health Care, 2E takes a novel approach to learning about and understanding ethics. It draws on practical experiences and contemporary issues in its exploration of the ethical choices made in health care. The common theme followed in the book is that health care ethics are not only about setting acceptable standards, they are also about reflecting on what health care professionals should aim towards. It is about reflecting on optimal standards, and pursuing those standards. In focusing on the (...) interaction between the health provider and his or her client, the book skillfully incorporates individual and group exercises to help the reader think about particular issues or standards, or particular styles of ethical reflection. Tutorial-type triggers and case studies are also included. Over fifty of these exercises, twenty-four of them new to this edition, assist in developing familiarity with the key ways of identifying, and working to resolve, ethical issues in health care. In this framework, the philosophical aspect of ethics become a tool that every potential and current health care worker can use to reflect on ethics as it applies to their profession. (shrink)

In this paper, we examine how a research institution’s social structure and academic opinion leaders’ presence shaped the early adoption of a scientific innovation. Our case considers the early engagement of mathematical economists at the Cowles Commission with John von Neumann and Oskar Morgenstern’s Theory of Games and Economic Behavior. We argue that scholars with administrative leadership functions who were not only scientifically but also organizationally central – in our case the director of research Jacob Marschak – played a crucial (...) role in promoting the adoption of the Theory of Games. We support our argument with a scientometric analysis of all acknowledgments made in 488 papers published from 1944 to 1955 in the two main paper series at Cowles. We apply blockmodeling techniques to the acknowledgments network to reconstruct the formal and informal social structure at Cowles at the time. Our findings suggest that studies of the early adoption of scientific theories benefit from complementary perspectives on the role of academic leaders and scientists. Our study reveals the importance of formal and informal social structures and the agenda of administrative leaders in these structures to explain their adoption. (shrink)

Through the contributions of specialists in the field, this volume addresses the still open question of the role and status of myth in Plato’s dialogues and thereby speaks to the broader problem of the relation between philosophy and ...

Stoic work on ambiguity represents one of the most innovative, sophisticated and rigorous contributions to philosophy and the study of language in western antiquity. This book is both a comprehensive survey of the often difficult and scattered sources, and an attempt to locate Stoic material in the rich array of contexts, ancient and modern, which alone can guarantee full appreciation of its subtlety, scope and complexity. The comparisons and contrasts which this book constructs will intrigue not just classical scholars, and (...) philosophers, but also logicians, theoretical linguists, communication theorists and historians of grammar and of literary theory. The Stoics on Ambiguity is designed to be intelligible to readers with no Greek or Latin. (shrink)

The Routledge Handbook of Women and Ancient Greek Philosophy is an essential reference source for cutting-edge scholarship on women, gender, and philosophy in Greek antiquity. The volume features original research that crosses disciplines, offering readers an accessible guide to new methods, new sources, and new questions in the study of ancient Greek philosophy and its multiple afterlives. Comprising 40 chapters from a diverse international group of experts, the Handbook considers questions about women and gender in sources from Greek antiquity spanning (...) the period from 7th c. BCE to 2nd c. BCE, and in receptions of Greek antiquity from the Roman Imperial period, through the European Renaissance to the current day. Chapters are organized into five major sections: I. Early Greek antiquity – including Sappho, Presocratic philosophy, Sophists, and Greek tragedy – 700s–400s BCE II. Classical Greek antiquity – including Aeschines, Plato, and Xenophon – 400s–300s BCE III. Late Classical Greek to Hellenistic antiquity – including Cyrenaics, Cynics, the Hippocratic corpus, and Aristotle – 300s–200s BCE IV. Late Greek antiquity to Roman Imperial period – including Pythagorean women, Stoics, Pyrrhonian Skeptics, and late Platonists – 200s BCE to 700s CE V. Later receptions – including Shakespeare, the European Renaissance, Anna Julia Cooper, W.E.B. DuBois, Jane Harrison, Sarah Kofman, and Toni Morrison The Routledge Handbook of Women and Ancient Greek Philosophy is a vital resource for students and scholars in philosophy, Classics, and gender studies who want to gain a deeper understanding of philosophy’s rich past and explore sources and questions beyond the traditional canon. The volume is a valuable resource, as well, for students and scholars from history, humanities, literature, political science, religious studies, rhetorical studies, theatre, and LGBTQ and sexuality studies. (shrink)

This book provides papers of the conference of leading scientists and philosophers on the notion of progress of knowledge, which is constitutive of our modern selfunderstanding, from the perspective of their disciplines. Summary of contents: 1. GEorg Henrik von Wright, Progress: Fiction and Fact 2. WAlter Burkert, Impact and Limits of the Idea of Progress in Antiquity 3. AListair Crombie, Philosophical Commitments and Scientific Progress 4. SHigeru Nakayama, Chinese "Cyclic" View of History vs Japanese "Progress" 5. JEan Blondel, Political Progress: (...) Illusion or Reality 6. NIcholas Rescher, Progress and the Future 7. RUdolf Flotzinger, Progress and Development in Musical History 8. DAg Pravitz, Progress in Philosophy 9. JOhn D. BArrow, Time in the Universe 10. ANtonio Garcia-Bellido, Progress in Biological Evolution 11. GEreon Wolters, The Idea of Progress in Evolutionary Biology: Philosophical Considerations 12. PHilippe Lazar, The Idea of Progress in Human Health. (shrink)

Analyse le lien entre le discours du philosophe E. Levinas et l'idée de Dieu qui sous-tend sa pensée. Parmi les thèmes abordés : la création, la prophétie, le temps, la sainteté.

Comment Œdipe en est-il arrivé à commettre deux crimes, le parricide et l’inceste? En se référant aux concepts de constellation œdipienne (S. Leclaire) et de configuration œdipienne (H. Faimberg), l’auteur étudie les personnages de la famille d’Œdipe. On voit ainsi qu’avant d’être parricide et incestueux, Œdipe est un enfant que ses parents veulent tuer. C’est aussi un enfant qui a été recueilli et adopté, mais sans en avoir connaissance, ni connaître ses origines. L’Œdipe roi de Sophocle se présente comme le (...) travail de remise en ordre des repères généalogiques brouillés par les mensonges de ses parents. Freud comparait la construction de cette pièce à un travail de psychanalyse. (shrink)

Why was Wollstonecraft's landmark feminist work, the Vindication of the Rights of Woman, categorised as a work of political economy when it was first published? Taking this question as a starting point, Mary Wollstonecraft and Political Economy gives a compelling new account of Wollstonecraft as critic of the material, moral, social, and psychological conditions of commercial modernity. Offering thorough analysis of Wollstonecraft's major writings - including her two Vindications, her novels, her history of the French Revolution, and her travel writing (...) - this is the only book-length study to situate Wollstonecraft in the context of the political economic thought of her time. It shows Wollstonecraft as an economic as much as a political radical, whose critique of the emerging economic orthodoxies of her time anticipates later Romantic thinkers. This title is part of the Flip it Open Programme and may also be available Open Access. Check our website Cambridge Core for details. (shrink)