The U.S. oversight system for genetically engineered organisms was evaluated to develop hypotheses and derive lessons for oversight of other emerging technologies, such as nanotechnology. Evaluation was based upon quantitative expert elicitation, semi-standardized interviews, and historical literature analysis. Through an interdisciplinary policy analysis approach, blending legal, ethical, risk analysis, and policy sciences viewpoints, criteria were used to identify strengths and weaknesses of GEOs oversight and explore correlations among its attributes and outcomes. From the three sources of data, hypotheses and broader (...) conclusions for oversight were developed. Our analysis suggests several lessons for oversight of emerging technologies: the importance of reducing complexity and uncertainty in oversight for minimizing financial burdens on small product developers; consolidating multi-agency jurisdictions to avoid gaps and redundancies in safety reviews; consumer benefits for advancing acceptance of GEO products; rigorous and independent pre- and post-market assessment for environmental safety; early public input and transparency for ensuring public confidence; and the positive role of public input in system development, informed consent, capacity, compliance, incentives, and data requirements and stringency in promoting health and environmental safety outcomes, as well as the equitable distribution of health impacts. Our integrated approach is instructive for more comprehensive analyses of oversight systems, developing hypotheses for how features of oversight systems affect outcomes, and formulating policy options for oversight of future technological products, especially nanotechnology products. (shrink)

U.S. approaches to oversight of research and technological products have developed over time in an effort to ensure safety to humans, animals, and the environment and to control use in a social context. In modern times, regulatory and oversight tools have evolved to include diverse approaches such as performance standards, tradable allowances, consultations between government and industry, and pre-market safety and efficacy reviews. The decision whether to impose an oversight system, the oversight elements, the level of oversight, the choice of (...) approach, and its execution can profoundly affect technological development, individual and collective interests, and public confidence in technological products. Oversight is conducted by a range of institutions with various capabilities, cultures, and motives. Avenues for disputing oversight decisions are also important, and some argue that the U.S. operates in an adversarial regulatory culture in which Congress, the media, and stakeholders regularly contest the decisions of federal agencies. (shrink)

At the forefront of international concerns about global legislation and regulation, a host of noted environmentalists and business ethicists examine ethical issues in consumption from the points of view of environmental sustainability, economic development, and free enterprise.

This commentary provides a brief overview of the methods and results presented by Jennifer Kuzma, Pouya Najmaie, and Joel Larson in “Evaluating Oversight Systems for Emerging Technologies: A Case Study of Genetically Engineered Organisms.” It offers suggestions regarding how supplemental information might be used to gain additional insights into the authors' results and how future research could further enhance our understanding of the attributes and outcomes of regulatory oversight for genetically engineered organisms.

This is a philosophical and historical investigation of the role of inconsistent representations of the same scientific phenomenon. The logical difficulties associated with the simultaneous application of inconsistent models are discussed. Internally inconsistent scientific proposals are characterized as structures whose application is necessarily tied to the confirming evidence that each of its components enjoys and to a vision of the general form of the theory that will resolve the inconsistency. Einstein's derivation of the black body radiation law is used as (...) an example application of such a strategy and is contrasted with planck's derivation. (shrink)

I argue here that the ways we experience, think about, and treat pain are bound up with sociocultural and technological phenomena that shape our desires and expectations. I propose a way of imagining caring for and offering healing to those who suffer pain informed by the Christian theological tradition. This way does not aspire to replace the care and healing made possible by modern medicine, but rather to place it within the common life of a community of mutual love, hospitality, (...) and reciprocal care. (shrink)

The literature has shown that different types of moral dilemmas elicit discrepant decision patterns. The present research investigated the role of uncertainty in contributing to these decision patterns. Two studies were conducted to examine participants' choices in commonly used dilemmas. Study 1 showed that participants’ perceived outcome probabilities were significantly associated with their moral choices, and that these associations were independent from the dilemma type. Study 2 revealed that participants had significantly less preference for killing the individual when the outcome (...) probabilities were stated using the modal verb ‘will’ than when they were stated using the numerical phrasing of ‘100%’. Our findings illustrate a discord between experimenter and participant in the interpretation of task instructions. (shrink)

There is growing philosophical interest in “affective injustice”: injustice faced by individuals specifically in their capacity as affective beings. Current debates tend to focus on affective injustice at the psychological level. In this paper, I argue that the built environment can be a vehicle for affective injustice — specifically, what Wildman et al. (2022) term “affective powerlessness”. I use resources from ecological psychology to develop this claim. I consider two cases where certain kinds of bodies are, either intentionally or unintentionally, (...) deprived of access to goods affording the development and maintenance of their subjective well-being: hostile architecture and masking practices in autism. This deprivation, I argue further, leads to a significant weakening and diminishment of their spatial agency, hinders their well-being, and in so doing gives rise to a pervasive experience of affective powerlessness. By drawing attention to these themes, I show that an ecological approach helpfully supplements existing approaches. It highlights how affective injustice can emerge via the way bodies are positioned in space, and the central role that built environments play in determining this positioning. (shrink)

As technology improves, artificial systems are increasingly able to behave in human-like ways: holding a conversation; providing information, advice, and support; or taking on the role of therapist, teacher, or counsellor. This enhanced behavioural complexity, we argue, encourages deeper forms of affective engagement on the part of the human user, with the artificial agent helping to stabilise, subdue, prolong, or intensify a person's emotional condition. Here, we defend a fictionalist account of human/AI interaction, according to which these encounters involve an (...) elaborate practise of imaginative pretence: a make-believe in which the artificial agent is attributed a life of its own. We attend, specifically, to the temporal characteristics of these fictions, and to what we imagine artificial agents are doing when we are not looking at them. (shrink)

I outline the theoretical framework of, and three research programs within American speculative philosophy of science during the period 1900-1931. One program applies verificationism to research in psychology, one investigates the methodology of research programs, and one analyses scientific explanation and other scientific concepts. The primary sources for my outline are works by Morris Raphael Cohen, Grace Andrus de Laguna, Theodore de Laguna, Edgar Arthur Singer Jr., Harold Robert Smart, and Marie Collins Swabey. I also use my outline to provide (...) a partial comparison of American speculative philosophy of science and 1930s logical positivism. My comparison suggests that logical positivism was a proposal for substantially narrowing down and winding back American philosophy of science and was based on positions that were already problematized in the American context. -/- . (shrink)

Logical analyses of scientific representations of the world have usually focused on axiomatized or axiomatizable theories. As practiced, science seldom employs such theories. Rather, we find aggregations of claims, the logical relations of which are not as neat as philosophers of science might like them to be. Indeed, a common feature of such aggregations is the presence of certain “theoretical anomalies,” statements that are in some way incompatible with the remainder of the corpus. Huygens’ description of light as exhibiting an (...) asymmetry with respect to its direction of propagation in polarization phenomena was such an anomaly because of its inconsistency with his account of light as longitudinal waves in a medium. (See Sabra 1981, pp. 226-227.) Although the occurrence of these anomalies is indicative of a problem that must be dealt with, inconsistent representations of the world are not without significant heuristic value. (shrink)

I revisit my paper, ‘Grace de Laguna’s 1909 Critique of Analytic Philosophy’ and respond to the commentary on it. I respond to James Chase and Jack Reynolds by further analysing the difference between speculative philosophy as de Laguna conceived of it and analytic philosophy, by clarifying how her critique of analytic philosophy remains relevant to some of its more speculative forms, and by explaining what justifies the criticism of established opinion that goes along with her rejection of analytic philosophy’s epistemic (...) conservatism. In response to Andreas Vrahimis, I contextualise my reading of de Laguna’s work in 1909. This clarifies her critique of pragmatism, distinguishes it from her critique of epistemically conservative philosophy, and shows that she was not only already aware of the full scope of the latter critique but is likely to have identified the then incipient analytic philosophy as its primary target. Also, contra Vrahimis, her argument is effective against Bertrand Russell’s later, epistemically conservative approach to philosophy. In response to Cheryl Misak, I point out that her argument that de Laguna is, despite herself, a pragmatist rests on a misunderstanding of the differences between pragmatism and idealism, and I show that de Laguna’s main early influences were Herbert Spencer and her teacher, James Edwin Creighton. I further argue that Misak’s rejection of de Laguna’s critique of pragmatism rests on a misrepresentation of the critique. (shrink)

I develop Tetsurō Watsuji’s relational model of the self as “betweenness”. I argue that Watsuji’s view receives support from two case studies: solitary confinement and dementia. Both clarify the constitutive interdependence between the self and the social and material contexts of “betweenness” that define its lifeworld. They do so by providing powerful examples of what happens when the support and regulative grounding of this lifeworld is restricted or taken away. I argue further that Watsuji’s view helps see the other side (...) of this deprivation, how reconstructing aspects of betweenness is, at the same time, a reconstruction of the self. I conclude by briefly indicating further consequences of this view. (shrink)

Ethical extensionism is a common argument pattern in environmental and animal ethics, which takes a morally valuable trait already recognized in us and argues that we should recognize that value in other entities such as nonhuman animals. I exposit ethical extensionism’s core argument, argue for its validity and soundness, and trace its history to 18th century progressivist calls to expand the moral community and legal franchise. However, ethical extensionism has its critics. The bulk of the paper responds to recent criticisms, (...) including (1) environmental ethicists’ objection against its austere conception of moral value (2), feminist ethicists’ claim that extensionism fails to account for the moral significance of difference, (3) disability theorists’ concern that ethical extensionist arguments are offensive, and (4) animal rights theorists’ lament that extensionism is a practical failure. While something is to be gained from each criticism, I argue that they ultimately fail and that extensionism remains compelling. (shrink)

I respond to the commentaries on 'Grace de Laguna's Analytic and Speculative Philosophy' offered by Peter Olen [2023], Trevor Pearce, Anthony Fisher, Marguerite La Caze and Frederique Janssen-Lauret. In doing so, I bring out some of the value of de Laguna’s perspectivism and of her treatment of modality. I also further clarify how she departs from pragmatism and from analytic philosophy, and how she relates to continental philosophy.

This article discusses the ways in which law functions as a determinant of health, historical collaborations between the health and legal professions, the benefits of creating medical-public health-legal collaborations, and how viewing law through a collaborative, population health lens can lead to health equity.

The way language as a human faculty has evolved is a question that preoccupies researchers from a wide spread of disciplines. In this book, a team of writers has been brought together to examine the evolution of language from a variety of such standpoints, including language's genetic basis, the anthropological context of its appearance, its formal structure, its relation to systems of cognition and thought, as well as its possible evolutionary antecedents. The book includes Hauser, Chomsky, and Fitch's seminal and (...) provocative essay on the subject, 'The Faculty of Language,' and charts the progress of research in this active and highly controversial field since its publication in 2002. This timely volume will be welcomed by researchers and students in a number of disciplines, including linguistics, evolutionary biology, psychology, and cognitive science. (shrink)

By titling his paper “Slowing the Slide Down the Slippery Slope of Medical Assistance in Dying: Mutual Learnings for Canada and the US,” Daryl Pullman, an esteemed medical ethicist, uses a rhetoric...

We present a variety of (ω 1 ,∞)-distributive forcings which when applied to models of Martin's Maximum separate certain well known reflection principles. In particular, we do this for the reflection principles SR, SR α (α ≤ ω 1 ), and SRP.

Our language and metaphors about environmental issues reflect and affect how we perceive and manage them. Discourse on invasive species is dominated by aggressive language of aliens and invasion, which contributes to the use of war-like metaphors to promote combative control. This language has been criticised for undermining scientific objectivity, misleading discourse, and restricting how invasive species are perceived and managed. Calls have been made for alternative metaphors that open up new management possibilities and reconnect with a deeper conservation ethic. (...) Here, we turn to Indigenous perspectives because they are increasingly recognised as offering important and novel voices in invasive species discourse. We examine how Australian Aboriginal elders and land managers (rangers) speak about 'environmental weeds' (the term used to describe invasive plants in Australia) and weed management. Based on qualitative research with five Aboriginal groups in the Kimberley region of Western Australia, our findings indicate that Aboriginal elders speak about weeds through passive, neutral language and prefer metaphors for weed management that focus on health, care and creation. We outline the influence that this language has for how rangers practice weed work and discuss its implications for the mainstream paradigm. (shrink)

Our primary goal in this article is to discuss the cross-talk between biological and cultural factors that become manifested in the individual brain development, neural wiring, neurochemical homeostasis, and behavior. We will show that behavioral propensities are the product of both cultural and biological factors and an understanding of these interactive processes can provide deep insights into why people behave the way they do. This interdisciplinary perspective is offered in an effort to generate dialog and empirical work among scholars interested (...) in merging aspects of anthropology and neuroscience, and anticipates that biological and cultural anthropology converge. We discuss new theoretical developments, hypothesis-testing strategies, and cross-disciplinary methods of observation and data collection. We believe that the exigency of integrating anthropology and the neurosciences is indisputable and anthropology's role in an emerging interdisciplinary science of human behavior will be critical because its focus is, and has always been, on human biological and cultural systems. (shrink)

The Necessary Maximality Principle for c. c. c. forcing with real parameters is equiconsistent with the existence of a weakly compact cardinal. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim).

If the Wholeness Axiom wa $_0$ is itself consistent, then it is consistent with v=hod. A consequence of the proof is that the various Wholeness Axioms are not all equivalent. Additionally, the theory zfc+wa $_0$ is finitely axiomatizable.

Unfoldable cardinals are preserved by fast function forcing and the Laver-like preparations that fast functions support. These iterations show, by set-forcing over any model of ZFC, that any given unfoldable cardinal κ can be made indestructible by the forcing to add any number of Cohen subsets to κ.

Culture, livelihoods and political-economic status all influence people's perception of introduced and invasive species, shaping perspectives on what sort of management of them, if any, is warranted. Indigenous voices and values are under-represented in scholarly discourse about introduced and invasive species. This paper examines the relationship between the Xeni Gwet'in First Nation (one of six Tsilhqot'in communities) and wild or free-roaming horses in British Columbia, Canada. We outline how Xeni Gwet'in people value horses and experience management actions, contextualising the controversy (...) over wild horses amidst power imbalances in the expression of environmental values. We suggest that Indigenous voices are vital to include when evaluating impacts of controversial species and developing management strategies. (shrink)

Consideration of affective dimensions beyond arousal may be useful for a more precise understanding of the effects of emotional events on episodic memory. As highlighted by Kensinger (2009), the valence of an event may differentially impact the accuracy of its recall. Paralleling work on attention, we propose that the relevance of an event or stimulus for survival may also importantly modulate memory accuracy. However, few memory studies to date have accounted for motivational relevance, and the stimuli employed in most studies (...) are not matched on this dimension. (shrink)

The content of Christian spirituality that made waves since the inception of the early church soon took on different contours as the faith got adapted to different gentile contexts. The expression of this faith, along with its liturgical symbolism and sacramental observances, is still gaining momentum in African Christianity. The emerging practice of the use of ‘anointing oil’ in its religious expression is receiving more attention than the Christ of the Gospel. In this article, we argue that against its primitive (...) intent, the use of the ‘anointing oil’ by the African Church is a mere display of fetish ancestral religion that expresses its unique African traditional religious root rather than a true expression of Christian spirituality. Our thesis is framed on the basis that the manner in which some African churches apply the purported ‘anointing oil’ is discriminatory vis-à-vis its ancient understanding and purpose. In our attempt to address this damaging practice to true Christian spirituality, also standing as a huge challenge for pastoral theology, we undertook a careful historical–theological analysis of the extant biblical data and its contextual interpretation vis-à-vis its distortion today. We concluded that what pastoral theologians have to deal with within the Christian community in Africa is offering the right biblical perspective against the distorted mode of the application of the contemporary purported ‘anointing oil’ that is falsely projecting the Christian faith and belief in a bad light. Contribution: The application of the anointing oil in contemporary Christian religion in Africa is, to say the least, not an inherent textually prescribed requisite criterion for Christian spirituality, but merely an outburst of fetish ancestral religious worldview that stands contra the hermeneutics of the biblical text and its ancient tradition. That no Old Testament prophet, not even Jesus nor Paul, mentioned the subject, makes its contemporary application textually and theologically suspect, and therefore, heretically infectious for the spiritual health of the community of faith. These insights sit quite well with the textual hermeneutics within the mainline transdisciplinary religious and multidisplinary theological perspective of this journal. (shrink)

The canonical function game is a game of length ω1 introduced by W. Hugh Woodin which falls inside a class of games known as Neeman games. Using large cardinals, we show that it is possible to force that the game is not determined. We also discuss the relationship between this result and Σ22 absoluteness, cardinality spectra and Π2 maximality for H(ω2) relative to the Continuum Hypothesis.

We introduce the subject of modal model theory, where one studies a mathematical structure within a class of similar structures under an extension concept that gives rise to mathematically natural notions of possibility and necessity. A statement φ is possible in a structure (written φ) if φ is true in some extension of that structure, and φ is necessary (written φ) if it is true in all extensions of the structure. A principal case for us will be the class Mod(T) (...) of all models of a given theory T—all graphs, all groups, all fields, or what have you—considered under the substructure relation. In this article, we aim to develop the resulting modal model theory. The class of all graphs is a particularly insightful case illustrating the remarkable power of the modal vocabulary, for the modal language of graph theory can express connectedness, k-colorability, finiteness, countability, size continuum, size ℵ1, ℵ2, ℵω, ℶω, first ℶ-fixed point, first ℶ-hyper-fixed point, and much more. A graph obeys the maximality principle φ(a)→φ(a) with parameters if and only if it satisfies the theory of the countable random graph, and it satisfies the maximality principle for sentences if and only if it is universal for finite graphs. (shrink)

What inductive biases must be incorporated into multi-agent artificial intelligence models to get them to capture high-fidelity imitation? We think very little is needed. In the right environments, both instrumental- and ritual-stance imitation can emerge from generic learning mechanisms operating on non-deliberative decision architectures. In this view, imitation emerges from trial-and-error learning and does not require explicit deliberation.