ABSTRACTPrevious studies have identified two powerful ways to regulate emotional responses to a stressor: experiencing incidental positive emotions and using cognitive reappraisal to reframe the stressor. Several cognitive and motivational theories of positive emotion support the formulation that incidental positive emotions may facilitate cognitive reappraisal. To test the separate and interacting effects of positive emotions and cognitive reappraisal, we first adapted an established picture-based reappraisal paradigm by interspersing blocks of positive emotion inducing and neutral pictures. Across two pre-registered studies, reappraisal (...) effectively decreased self-reported negative emotions and increased self-reported positive emotions; however, experiencing incidental positive emotions did not facilitate reappraisal success. In another preregistered study, we employed a more powerful positive emotion induction via virtual reality, used a social stress anticipation task, and... (shrink)

There is mounting evidence that language comprehension involves the activation of mental imagery of the content of utterances (Barsalou, 1999;Bergen, Chang, & Narayan, 2004;Bergen, Narayan, & Feldman, 2003;Narayan, Bergen, & Weinberg, 2004;Richardson, Spivey, McRae, & Barsalou, 2003;Stanfield & Zwaan, 2001;Zwaan, Stanfield, & Yaxley, 2002). This imagery can have motor or perceptual content. Three main questions about the process remain under‐explored, however. First, are lexical associations with perception or motion sufficient to yield mental simulation, or is the integration of lexical (...) semantics into larger structures, like sentences, necessary? Second, what linguistic elements (e.g., verbs, nouns, etc.) trigger mental simulations? Third, how detailed are the visual simulations that are performed? A series of behavioral experiments address these questions, using a visual object categorization task to investigate whether up‐ or down‐related language selectively interferes with visual processing in the same part of the visual field (followingRichardson et al., 2003). The results demonstrate that either subject nouns or main verbs can trigger visual imagery, but only when used in literal sentences about real space—metaphorical language does not yield significant effects—which implies that it is the comprehension of the sentence as a whole and not simply lexical associations that yields imagery effects. These studies also show that the evoked imagery contains detail as to the part of the visual field where the described scene would take place. (shrink)

The paper seeks to give an ontological account of idea as mental content in the philosophy of John Locke. The foundation on which to place and polarise philosophical standpoints with regard to this issue is the 17th- century controversy between J. Locke and N. Malebranche with respect to the genesis of human knowledge. Showing the foundation of this controversy, as expressed in the polemic work of Locke entitled An Examination of P. Malebranche\'s Opinion of Seeing All Things in God, I (...) shall outline two possible approaches to our mental contents, namely the psychologistic and anti-psychologistic ones. In this perspective Locke is a representative of the first standpoint, whereas Malebranche of the second. In the psychologistic approach, the content of our conscious acts (or according to 17th-century Cartesian philosophy ideas) is exclusively an internalelement of this consciousness. On the contrary – in the case of the anti- psychologistic characteristation, the content of our consciousness is described as ontologically antonomous, i.e. as independent from thr knowing subject. Following the analyses of An Examination, I obtain additional arguments on behalf of the psychologistic interpretation of Locke\'s conception of idea (expressed, among others, by J. Yolton and M. Ayers), contrary to the anti-psychologistic approaches (claimed by, among others, T. Reid, R. McRae, and N. Jolley). (shrink)

Kenny, A. Descartes on the will.--McRae, R. Innate ideas.--McRae, R. Descartes' definition of thought.--Gombay, A. Cogito ergo sum: inference or argument?--Ashworth, E. J. Descartes' theory of clear and distinct ideas.--Alexander, R. E. The problem of metaphysical doubt and its removal.--Tweyman, S. The reliability of reason.--Percival, W. K. On the non-existence of Cartesian linguistics.

In lieu of an abstract, here is a brief excerpt of the content:172. THE HUME LITERATURE FOR 1981 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; jê9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1980 were listed in Hume Studies for the last four Novembers. What follows here will bring the record up to (...) the end of 1981. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPReview Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly fol· low the British Standard (no. 4148). BAGOLINI, L. 'Legal Obligation in Hume', Hume Studies 7, 85-93. BAIER, A. 'Frankena and Hume on Points of View', The Monist 64, 342-58. BATTERSBY, C. 'An Enquiry concerning the Humean Woman', Philosophy 56, 303-12. 173. BEAUCHAMP, T. L. & ROSENBERG, A. Hume and the Problem of Causation, (xxv, 340 pp.) New York. [PB 23 (1982) 129-48 (Mackie, Flew, Beauchamp & Rosenberg) ] BOTWINICK, A. 'Hume on Is-Ought', Auslegung 8, 19-30. BURNS, R. M. The Great Debate on Miracles, esp. chs. 6-8. Lewisburg, London & Toronto. COSTA, M. J. 'Hume and Justified Belief, Can. J. Phil. 11, 219-28. CRONIN, R. Shelley's Poetic Thoughts, 77-83. London. DE MARTELAERE, P. 'Hume's "Gematigd" Scepticisme: Futiel of Fataal', Tijdschrift voor Filosofie 43, 427-64. DILMAN, I. Studies in Language and Reason, chs. 4-5. London. FARR, W. Hume and Kant: Studienbuch zum Erkenntsnisproblem. (250 pp.) Freiburg & Munich. FEINSTEIN, R. 'Some Problems in Humean Philosophy', Ind. phil. Q. 8, 527-32. FLAGE, D. E. 'Hume's Relative Ideas', Hume Studies 7, 55-73. GARCIA ROCA, J. Positivismo e Ilustración : La filosofía de David Hume. (304 pp.) Valencia. GARRETT, D. 'Hume's Self-Doubts about Personal Identity', PR 90, 337-58. GUPTA, B. 'Scepticism: Ancient "East" and Modern "West"', Ind. phil. Q. 9, 29-44. HAAKONSSEN, K. The Science of a Legislator, the Natural Jurisprudence? of David Hume and Adam Smith. Cambridge. HALL, R. 'The Hume Literature for 1980', Hume Studies 7, 184-90. íiARRISON, J. Hume's Theory of Justice. (xxvi, 304 pp.) Oxford. [THES no. 440 (3 Apr. 1981) 15] IMLAY, R. A. 'Hume's Of Scepticism with regard to reason: A Study in Contrasting Themes', Hume Studies 7, 121-36. JOHNSON, 0. A. 'Hume's "True" Scepticism', Pacific phil. Q. 62, 403-10. JONES, G. E. 'Vindication, Hume, and Induction', Can. J. Phil. 12, 119-29. 174. KING, J. 'Hume's Classical Theory of Justice', Hume Studies 7, 32-54. KULENKAMPFF, J. 'David Hume (1711-1776)', in 0. Hoffe, Klassiker der Philosophie, vol. 1, 434-56. Munich. LOEB, L. E. From Descartes to Hume, sec. 39 (354-63). Ithaca & London. MACLEOD, A. "Rule-Utilitarianism and Hume's Theory of Justice', Hume Studies 7, 74-84. MAHER, P. 'Probability in Hume's Science of Man', Hume Studies 7, 137-53. MALHERBE, M. 'Les études humiennes: anatomie et problèmes1, Archives de Philosophie 44, 637-71. MILLER, D. Philosophy and Ideology in Hume's Political ThoughtT (218 pp.) Oxford. [London Rev, of Bks 4 (1982), no. 7, 22-4; PB 23 (1982) 206-9] MONTEIRO, J. P. 'Hume's Conception of Science', JHP 19, 327-42. NEWMAN, R. 'Hume on Space and Geometry', Hume Studies 7, 1-31. NIELSON, H. A. 'Inference and Experience in Hume's Enquiry', Phil. Res. Archives 7, no. 1471. NORTH, T. 'What if I'm Indifferent?', Phil. Investigations 4, 24-37. PAPPAS, G. S. 'On McRae's Hume', Hume Studies... (shrink)

In this study a combination of computer tools for coupling and virtual screening is detailed, in 108 active molecules and 3620 decoys to find stabilizers for G quadruplex. To have more precise results, combinations of coupling programs with fifteen energy scoring functions were applied. The validation and evaluation of the metrics was done with the CompScore genetic algorithm. The results showed an increase in BEDROC and EF of 50% compared to other strategies, as well as reflecting early recognition of active (...) molecules. From these results it is possible to work with the molecules that showed a good early recognition and evaluate their effect as G4 stabilizers. This ensures more efficient and accurate results in the preclinical stage for the development of anticancer drugs. Keywords: Enrichment metrics; telomere; G quadruplex ; CompScore. References [1]M. Porru, P. Zizza, M. Franceschin, C. Leonetti and A. Biroccio. «EMICORON: A multi-targeting G4 ligand with a promising preclinical profile» 2017. Biochimica et Biophysica Acta - General Subjects, 1861, 1362–1370. [Online]. Available: https://doi.org/10.1007/s00294-018-0836-6. [2]K. Tomita. «How long does telomerase extend telomeres? Regulation of telomerase release and telomere length homeostasis». Current Genetics, 64, 1177–1181. 2018. [Online]. Available: https://doi.org/10.1016/j.bbagen. 2016.11.010. [3]M. Jafri, S. Ansari, M. Alqahtani and J. Shay. «Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies. Genome Medicine., 2016. [Online]. Available: https://doi.org/10.3390/ijms19020482. [4]J. Huppert and S. Balasubramanian. «G-quadruplexes in promoters throughout the human genome». 35, 406–413. 2007. [Online]. Available: https://doi.org/10.1016/j.bbapap.2017.06.012. [5]S. Joy, Vijayakumar, S. Choi and H. Sunhye. «Role of computer-aided drug design in modern drug discovery». Archives of Pharmacal Research. 2015. [Online]. Available: https://doi.org/10.1007/s12272-015-0640-5. [6]S. Asamitsu, S. Obata, Z. Yu, T. Bando and H. Sugiyama. «Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy». Molecules, 24, 429. 2019. [En línea]. Available: https://doi.org/10.3390/molecules24030429. [7]R. Monsen and J. Trent. «Biochimie G-quadruplex virtual drug screening : A review». Biochimie, 152, 134–148. 2018. [Online]. Available: https://doi.org/10.1039/c9cc06748e. [8]J. Beauvarlet, P. Bensadoun, E. Darbo, G. Labrunie, E. Richard, I. Draskovic and M. Djavaheri-mergny. «Modulation of the ATM / autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells». 1–18. 2019. [Online]. Available: https://doi.org/10.1093/nar/gkz095. [9].Z. Crees, J. Girard, Z. Rios, G. Botting, K. Harrington and C. Shearrow. « Oligonucleotides and G-quadruplex stabilizers: targeting telomeres and telomerase in cancer therapy».2014. [Online]. Available: https://doi.org/10.2174/1381612820666140630100702. [10].M. Meier, A. Moya-torres, N. Krahn, M. Mcdougall, L. Orriss, E. Mcrae and T. Patel. «Structure and hydrodynamics of a DNA Gquadruplex with a cytosine bulge»., 1–13. 2018. [Online]. Available: https://doi.org/10.1093/nar/gky307. (shrink)

This monograph attempts to clarify one significant but much neglected aspect of Peirce's contribution to the philosophy of science. It was written in 1963 as my M. A. thesis at the Uni versity of Illinois. Since the topic is still neglected it is hoped that its pUblication will be of use to Peirce scholars. I should like to acknowledge my indebtedness to Dr. Max Fisch who broached this topic to me and who advised me con tinuously through its development, assisting (...) generously with his own insights and unpublished Peirce manuscripts. TABLE OF CONTENTS INTRODUCTION 1. A Current Issue in the Philosophy of Science 1 2. Peirce and His Theory of Abduction 5 3. The General Character of Abduction 7 PART I: THE EARLY THEORY 1. Peirce's Earliest Conception of Inference 11 2. Three Kinds of Inference and Three Figures of Syllogism 13 3. Ampliative Inference and Cognition 17 4. Induction and Hypothesis 20 5. The Method of Methods 23 PART II: THE LATER THEORY 1. The Transitional Period 28 2. Three Stages of Inquiry 31 3. Abduction and Guessing Instinct 35 4. Logic as a Normative Science 38 5. Hypothesis Construction and Selection 41 6. Abduction and Pragmatism 44 7. Economy of Research 47 8. Justification of Abduction 51 CONCLUSION 55 61 BIBLIOGRAPHY INTRODUCTION 1. (shrink)

In our article (Zawadzki and Adamczyk 2021), we analyzed threats that novel memory modifying interventions may pose in the future. More specifically, we discussed how optogenetics’ potential for reversible erasure/deactivation of memory “may impact authenticity by producing changes at different levels of personality.” Our article has received many thoughtful open peer commentaries for which we would like to express our great appreciation. We have identified two main threads of objections. They are related to the potential applicability of optogenetics as a (...) therapeutic memory modification technology (MMT) in humans—applicability thread, and the normative value of authenticity, that is, the assumption that preserving authenticity is valuable (either in general or in the particular approach we adopted)—normative thread. Both of these threads concern fundamental issues: The former deals with the scientific credibility of the case vignette on which our discussion is based, and the latter deals with the normative weight of our considerations. We think that addressing both of them can be instructive in a broader context as they reflect a more general disagreement among neuroethicists about the very purpose and method of our discipline. (shrink)

The author introduces and critically analyzes two recent, curious findings and their accompanying explanations regarding how the folk intuits the capabilities of the dead and those in a persistent vegetative state. The dead are intuited to survive death, whereas PVS patients are intuited as more dead than the dead. Current explanations of these curious findings rely on how the folk is said to conceive of death and the dead: either as the annihilation of the person, or that person’s continuation as (...) a disembodied being. The author argues that these two conceptions are incompatible and inconsistent with each other and the evidence. Contrariwise, the author argues that the folk intuition about dead-survivors and the living dead are more easily explained by appealing to cross-culturally established concepts: the folk biological concept of death the existential concept of death, and the concept of social death. (shrink)

The covariant Klein-Gordon equation requires twice the boundary conditions of the Schrödinger equation and does not have an accepted single-particle interpretation. Instead of interpreting its solution as a probability wave determined by an initial boundary condition, this paper considers the possibility that the solutions are determined by both an initial and a final boundary condition. By constructing an invariant joint probability distribution from the size of the solution space, it is shown that the usual measurement probabilities can nearly be recovered (...) in the non-relativistic limit, provided that neither boundary constrains the energy to a precision near ℏ/t 0 (where t 0 is the time duration between the boundary conditions). Otherwise, deviations from standard quantum mechanics are predicted. (shrink)

J. L. Austin (1911-1960) exercised in Post-war Oxford an intellectual authority similar to that of Wittgenstein in Cambridge. Although he completed no books of his own and published only seven papers, Austin became through lectures and talks one of the acknowledged leaders in what is called ‘Oxford philosophy’ or ‘ordinary language philosophy’. Few would dispute that among analytic philosophers Austin stands out as a great and original philosophical genius. Three volumes of his writing, published after his death, have become classics (...) in analytical philosophy: Philosophical Papers ; Sense and Sensibilia ; and How to Do Things with Words . First published in 1969, this book is a collection of critical essays on Austin’s philosophy written by well-known philosophers, many of whom knew Austin personally. A number of essays included were especially written for this volume, but the majority have appeared previously in various journals or books, not all easy to obtain. (shrink)

A time-symmetric formulation of nonrelativistic quantum mechanics is developed by applying two consecutive boundary conditions onto solutions of a time- symmetrized wave equation. From known probabilities in ordinary quantum mechanics, a time-symmetric parameter P0 is then derived that properly weights the likelihood of any complete sequence of measurement outcomes on a quantum system. The results appear to match standard quantum mechanics, but do so without requiring a time-asymmetric collapse of the wavefunction upon measurement, thereby realigning quantum mechanics with an important (...) fundamental symmetry. (shrink)

Developing the Horizons of the Mind is a comprehensive book on Relational and Contextual Reasoning, a theory of the human mind which powerfully addresses key areas of human conflict such as the ideological conflict between nations, the conflict in close relationships and the conflict between science and religion. K. Helmut Reich provides a clear and accessible introduction to the fresh RCR way of thinking that encourages people to adopt an inclusive rather than an oppositional approach to conflict and problem-solving. Part (...) one outlines the key aspects of RCR theory and supporting empirical data and part two provides examples of its application in the world. RCR provides a stimulating and challenging tool to several disciplines, including philosophy, psychology, religious studies and education, and this book will be a valuable resource for cognitive scientists, psychotherapists, theologians, educators and all those involved in conflict resolution. (shrink)

I argue that there is a version of (quasi-Armstrongian) weak illusionism that intelligibly relates phenomenal concepts and introspective opacity, accounts for the (hard) problem intuitions Chalmers highlights (modal, epistemic, explanatory, and metaphysical), and undermines the most important arguments Chalmers deploys against type-B and type-C materialisms. If this is successful, we can satisfactorily account for the meta-problem of consciousness, mollify our hard problem intuitions, and remain genuine realists about phenomenal experience.

In mirror mark tests dolphins twist, posture, and engage in open-mouth and head movements, often repetitive. Because postures and an open mouth are also dolphin social behaviours, we used self-view television as a manipulatable mirror to distinguish between self-examination and social behavior. Two dolphins were exposed to alternating real-time self-view and playback of the same to determine if they distinguished between them. The adult male engaged in elaborate open-mouth behaviors in mirror mode, but usually just watched when playing back the (...) same material. Mirror mode behavior was also compared to interacting with real dolphins . Mark tests were conducted, as well as switches from front to side self-views to see if the dolphins turned. They presented marked areas to self-views to see if the dolphins turned. They presented marked areas to the self-view television and turned. The results suggest self-examination over social behavior. (shrink)

Written by leading researchers in educational and social psychology, learning science, and neuroscience, this edited volume is suitable for a wide-academic readership. It gives definitions of key terms related to motivation and learning alongside developed explanations of significant findings in the field. It also presents cohesive descriptions concerning how motivation relates to learning, and produces a novel and insightful combination of issues and findings from studies of motivation and/or learning across the authors' collective range of scientific fields. The authors provide (...) a variety of perspectives on motivational constructs and their measurement, which can be used by multiple and distinct scientific communities, both basic and applied. (shrink)

Papers presented at an annual inter-disciplinary seminar held to facilitate the 60th birthday of Kalarikkal Poulose Aleaz, b. 1947, theologist from Kerala, India during 20-21 September 2007.