Ernst Mayr argued that the emergence of biology as a special science in the early nineteenth century was possible due to the demise of the mathematical model of science and its insistence on demonstrative knowledge. More recently, John Zammito has claimed that the rise of biology as a special science was due to a distinctive experimental, anti-metaphysical, anti-mathematical, and anti-rationalist strand of thought coming from outside of Germany. In this paper we argue that this narrative neglects the important (...) role played by the mathematical and axiomatic model of science in the emergence of biology as a special science. We show that several major actors involved in the emergence of biology as a science in Germany were working with an axiomatic conception of science that goes back at least to Aristotle and was popular in mid-eighteenth-century German academic circles due to its endorsement by Christian Wolff. More specifically, we show that at least two major contributors to the emergence of biology in Germany—Caspar Friedrich Wolff and Gottfried Reinhold Treviranus—sought to provide a conception of the new science of life that satisfies the criteria of a traditional axiomatic ideal of science. Both C.F. Wolff and Treviranus took over strong commitments to the axiomatic model of science from major philosophers of their time, Christian Wolff and Friedrich Wilhelm Joseph Schelling, respectively. The ideal of biology as an axiomatic science with specific biological fundamental concepts and principles thus played a role in the emergence of biology as a special science. (shrink)

This article illustrates how axiomatic social choice theory can be used in the evaluation of measures of group fitness for a biological hierarchy, thereby contributing to the dialogue between the philosophy of biology and social choice theory. It provides an axiomatic characterization of the ordering underlying the MichodSolariNedelcu index of group fitness for a multicellular organism. The MVSHN index has been used to analyse the germ-soma specialization and the fitness decoupling between the cell and organism levels that (...) takes place during the evolutionary transition to multicellularity. It is argued that some of the axioms satisfied by the MVSHN group fitness ordering are not appropriate for all stages in this transition. (shrink)

Prompted by the thesis that an organism’s umwelt possesses not just a descriptive dimension, but a normative one as well, some have sought to annex semiotics with ethics. Yet the pronouncements made in this vein have consisted mainly in rehearsing accepted moral intuitions, and have failed to concretely further our knowledge of why or how a creature comes to order objects in its environment in accordance with axiological charges of value or disvalue. For want of a more explicit account, theorists (...) writing on the topic have relied almost exclusively on semiotic insights about perception originally designed as part of a sophisticated refutation of idealism. The end result, which has been a form of direct givenness, has thus been far from convincing. In an effort to bring substance to the right-headed suggestion that values are rooted in the biological and conform to species-specific requirements, we present a novel conception that strives to make explicit the elemental structure underlying umwelt normativity. Building and expanding on the seminal work of Ayn Rand in metaethics, we describe values as an intertwined lattice which takes a creature’s own embodied life as its ultimate standard; and endeavour to show how, from this, all subsequent valuations can in principle be determined. (shrink)

In 1900 David Hilbert announced his famous list of then-opened mathematical problems; the problem number 6 in this list is axiomatization of physical theories. Since then a lot of systematic efforts have been invested into solving this problem. However the results of these efforts turned to be less successful than the early enthusiasts of axiomatic method expected. The existing axiomatizations of physical and biological theories provide a valuable logical analysis of these theories but they do not constitute anything like (...) their standard presentation,which can be used for transmission, evaluation, and justification of physical and biological knowledge. This state of theart in the axiomatization of physics is strong evidence that the standard notion of axiomatic theory stemming from Hilbert and Tarski is not appropriate for thet ask. However in the recent years in mathematics there emerged a new axiomatic approach best represented by the Homotopy Type theory (HoTT). We argue that the constructive axiomatic architecture used in HoTT has better chances to be successfully applied in physics as well as in computer science and engineering. (shrink)

In 1900 David Hilbert announced his famous list of then-opened mathematical problems; the problem number 6 in this list is axiomatization of physical theories. Since then a lot of systematic efforts have been invested into solving this problem. However the results of these efforts turned to be less successful than the early enthusiasts of axiomatic method expected. The existing axiomatizations of physical and biological theories provide a valuable logical analysis of these theories but they do not constitute anything like (...) their standard presentation,which can be used for transmission, evaluation, and justification of physical and biological knowledge. This state of theart in the axiomatization of physics is strong evidence that the standard notion of axiomatic theory stemming from Hilbert and Tarski is not appropriate for thet ask. However in the recent years in mathematics there emerged a new axiomatic approach best represented by the Homotopy Type theory (HoTT). We argue that the constructive axiomatic architecture used in HoTT has better chances to be successfully applied in physics as well as in computer science and engineering. (shrink)

This volume draws together Allan Gotthelf's pioneering work on Aristotle's biology. He examines Aristotle's natural teleology, the axiomatic structure of biological explanation, and the reliance on scientifically organized data in the three great works with which Aristotle laid the foundations of biological science.

Presupposing little knowledge of biology, this introductory work focuses on the question of "whether or not biology is a science like the sciences of physics and chemistry." In so doing, it attempts to unify various philosophical issues arising in biology; namely, the relationships among Mendelian, population and molecular genetics, the connection between evidence and conclusion in evolutionary theory, the definitional basis for taxonomy, and the epistemological status of teleology. In support of his claim that "evolutionists have the (...) hypothetico-deductive model as an ideal in some sense," Ruse finds certain fundamental laws in the theory, and he argues for the necessity of covering-law explanations which parallel those of the physical sciences. Further, he sees population genetics as being already "in fact axiomatized" and hence forming the deductive "core" for the entirety of evolutionary biology. Although the author recognizes the complexity of the practical problems which arise in his quest for a "logically rigorous deductive theory," he "can see no good theoretical reasons standing in the way of a deductive evolutionary theory," and he asserts that "the history of evolutionary theory seems to point toward an even greater exemplification of the axiomatic ideal." In short, biology is found to be within the same realm as physics. (shrink)

This paper critically discusses two areas of Sahotra Sarkar’s recent work in environmental philosophy : biodiversity and conservation biology and roles for decision theory in incorporating values explicitly in the environmental policy process. I argue that Sarkar’s emphasis on the practices of conservation biologists, and especially the role of social and cultural values in the choice of biodiversity constituents, restricts his conception of biodiversity to particular practical conservation contexts. I argue that life scientists have many reasons to measure many (...) types of diversity, and that biodiversity metrics could be value-free. I argue that Sarkar’s emphasis on the limitations of normative decision theory is in tension with his statement that decision theory can “put science and ethics together.” I also challenge his claim that multi-criteria decision tools lacking axiomatic foundations in preference and utility theory are “without a rational basis,” by presenting a case of a simple “outranking” multi-criteria decision rule that can violate a basic normative requirement of preferences and ask whether there may nevertheless be contexts in which such a procedure might assist decision makers. (shrink)

The writings of Joseph Henry Woodger (1894–1981) are often taken to exemplify everything that was wrongheaded, misguided, and just plain wrong with early twentieth-century philosophy of biology. Over the years, commentators have said of Woodger: (a) that he was a fervent logical empiricist who tried to impose the explanatory gold standards of physics onto biology, (b) that his philosophical work was completely disconnected from biological science, (c) that he possessed no scientific or philosophical credentials, and (d) that his (...) work was disparaged – if not altogether ignored – by the biologists and philosophers of his era. In this paper, we provide the first systematic examination of Woodger’s oeuvre, and use it to demonstrate that the four preceding claims are false. We argue that Woodger’s ideas have exerted an important influence on biology and philosophy, and submit that the current consensus on his legacy stems from a highly selective reading of his works. By rehabilitating Woodger, we hope to show that there is no good reason to continue to disregard the numerous contributions to the philosophy of biology produced in the decades prior to the professionalization of the discipline. (shrink)

This article is a systematic critical survey of work done in the philosophy of biology within the logical empiricist tradition, beginning in the 1930s and until the end of the 1950s. It challenges a popular view that the logical empiricists either ignored biology altogether or produced analyses of little value. The earliest work on the philosophy of biology within the logical empiricist corpus was that of Philipp Frank, Ludwig von Bertalanffy, and Felix Mainx. Mainx, in particular, provided (...) a detailed analysis of biology in the 1930s and 1940s in his contribution to the logical empiricists’ Encyclopedia of Unified Science. However, the most important contributions to the philosophy of biology were those of Joseph Henry Woodger and Ernest Nagel. Woodger is primarily remembered for deploying the axiomatic method in biology but he also used semiformal methods for the analysis of many biological problems. While Woodger’s axiomatic work was often derided by some later philosophers of biology (e.g., David Hull and Michael Ruse), this article defends both the biological and the philosophical significance of some of that work, for instance, those aspects that led to the recognition of the conceptual complexity of mereology and temporal identity in biological systems. Woodger’s semiformal analyses were even more important, for instance, his explication of the concepts of the Bauplan and of innateness. Nagel’s importance lies in his analyses of reduction and emergence in the context of all empirical sciences and his use of these analyses in a careful exploration of biological problems. While Nagel’s model of reduction was generally rejected by philosophers of science in the 1970s and 1980s, particularly for biological contexts, it has recently been sympathetically reconstructed by many commentators; this article defends its continued relevance for the philosophy of biology. (shrink)

Biology is seen not merely as a privileged oppressor of women but as a co-victim of masculinist social assumptions. We see feminist critique as one of the normative controls that any scientist must perform whenever analyzing data, and we seek to demonstrate what has happened when this control has not been utilized. Narratives of fertilization and sex determination traditionally have been modeled on the cultural patterns of male/female interaction, leading to gender associations being placed on cells and their components. (...) We also find that when gender biases are controlled, new perceptions of these intracellular and extracellular relationships emerge. (shrink)

The Cell Ontology (CL) is designed to provide a standardized representation of cell types for data annotation. Currently, the CL employs multiple is_a relations, defining cell types in terms of histological, functional, and lineage properties, and the majority of definitions are written with sufficient generality to hold across multiple species. This approach limits the CL’s utility for cross-species data integration. To address this problem, we developed a method for the ontological representation of cells and applied this method to develop a (...) dendritic cell ontology (DC-CL). DC-CL subtypes are delineated on the basis of surface protein expression, systematically including both species-general and species-specific types and optimizing DC-CL for the analysis of flow cytometry data. This approach brings benefits in the form of increased accuracy, support for reasoning, and interoperability with other ontology resources. 104. Barry Smith, “Toward a Realistic Science of Environments”, Ecological Psychology, 2009, 21 (2), April-June, 121-130. Abstract: The perceptual psychologist J. J. Gibson embraces a radically externalistic view of mind and action. We have, for Gibson, not a Cartesian mind or soul, with its interior theater of contents and the consequent problem of explaining how this mind or soul and its psychological environment can succeed in grasping physical objects external to itself. Rather, we have a perceiving, acting organism, whose perceptions and actions are always already tuned to the parts and moments, the things and surfaces, of its external environment. We describe how on this basis Gibson sought to develop a realist science of environments which will be ‘consistent with physics, mechanics, optics, acoustics, and chemistry’. (shrink)

We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of neurological diseases and their associated signs and symptoms, assessments, diagnoses, and interventions that are encountered in the course of clinical practice. ND is built as an extension of the Ontology for General Medical Sciences — a high-level candidate OBO Foundry ontology that (...) provides a set of general classes that can be used to describe general aspects of medical science. ND is being built with classes utilizing both textual and axiomatized definitions that describe and formalize the relations between instances of other classes within the ontology itself as well as to external ontologies such as the Gene Ontology, Cell Ontology, Protein Ontology, and Chemical Entities of Biological Interest. In addition, references to similar or associated terms in external ontologies, vocabularies and terminologies are included when possible. Initial work on ND is focused on the areas of Alzheimer’s and other diseases associated with dementia, multiple sclerosis, and stroke and cerebrovascular disease. Extensions to additional groups of neurological diseases are planned. The second ontology, the Neuro-Psychological Testing Ontology (NPT), is intended to provide a set of classes for the annotation of neuropsychological testing data. The intention of this ontology is to allow for the integration of results from a variety of neuropsychological tests that assay similar measures of cognitive functioning. Neuro-psychological testing is an important component in developing the clinical picture used in the diagnosis of patients with a range of neurological diseases, such as Alzheimer’s disease and multiple sclerosis, and following stroke or traumatic brain injury. NPT is being developed as an extension to the Ontology for Biomedical Investigations. (shrink)

The need for quantitative measurement represents a unifying bond that links all the physical, biological, and social sciences. Measurements of such disparate phenomena as subatomic masses, uncertainty, information, and human values share common features whose explication is central to the achievement of foundational work in any particular mathematical science as well as for the development of a coherent philosophy of science. This book presents a theory of measurement, one that is "abstract" in that it is concerned with highly general axiomatizations (...) of empirical and qualitative settings and how these can be represented quantitatively. It was inspired by, and represents a generalization and extension of, the last major research work in this field, Foundations of Measurement Vol. I, by Krantz, Luce, Suppes, and Tversky published in 1971. (shrink)

This thesis focuses on models of conceptual change in science and philosophy. In particular, I developed a new bootstrapping methodology for studying conceptual change, centered around the formalization of several popular models of conceptual change and the collective assessment of their improved formal versions via nine evaluative dimensions. Among the models of conceptual change treated in the thesis are Carnap’s explication, Lakatos’ concept-stretching, Toulmin’s conceptual populations, Waismann’s open texture, Mark Wilson’s patches and facades, Sneed’s structuralism, and Paul Thagard’s conceptual revolutions. (...) -/- In order to analyze and compare the conception of conceptual change provided by these different models, I rely on several historical reconstructions of episodes of scientific conceptual change. The historical episodes of scientific change that figure in this work include the emergence of the morphological concept of fish in biological taxonomies, the development of scientific conceptions of temperature, the Church-Turing thesis and related axiomatizations of effective calculability, the history of the concept of polyhedron in 17th and 18th century mathematics, Hamilton’s invention of the quaternions, the history of the pre-abstract group concepts in 18th and 19th century mathematics, the expansion of Newtonian mechanics to viscous fluids forces phenomena, and the chemical revolution. I will also present five different formal and informal improvements of four specific models of conceptual change. I will first present two different improvements of Carnapian explication, a formal and an informal one. My informal improvement of Carnapian explication will consist of a more fine-grained version of the procedure that adds an intermediate, third step to the two steps of Carnapian explication. I will show how this novel three-step version of explication is more suitable than its traditional two-step relative to handle complex cases of explications. My second, formal improvement of Carnapian explication will be a full explication of the concept of explication itself within the theory of conceptual spaces. By virtue of this formal improvement, the whole procedure of explication together with its application procedures and its pragmatic desiderata will be reconceptualized as a precise procedure involving topological and geometrical constraints inside the theory of conceptual spaces. My third improved model of conceptual change will consist of a formal explication of Darwinian models of conceptual change that will make vast use of Godfrey-Smith’s population-based Darwinism for targeting explicitly mathematical conceptual change. My fourth improvement will be dedicated instead to Wilson’s indeterminate model of conceptual change. I will show how Wilson’s very informal framework can be explicated within a modified version of the structuralist model-theoretic reconstructions of scientific theories. Finally, the fifth improved model of conceptual change will be a belief-revision-like logical framework that reconstructs Thagard’s model of conceptual revolution as specific revision and contraction operations that work on conceptual structures. -/- At the end of this work, a general conception of conceptual change in science and philosophy emerges, thanks to the combined action of the three layers of my methodology. This conception takes conceptual change to be a multi-faceted phenomenon centered around the dynamics of groups of concepts. According to this conception, concepts are best reconstructed as plastic and inter-subjective entities equipped with a non-trivial internal structure and subject to a certain degree of localized holism. Furthermore, conceptual dynamics can be judged from a weakly normative perspective, bound to be dependent on shared values and goals. Conceptual change is then best understood, according to this conception, as a ubiquitous phenomenon underlying all of our intellectual activities, from science to ordinary linguistic practices. As such, conceptual change does not pose any particular problem to value-laden notions of scientific progress, objectivity, and realism. At the same time, this conception prompts all our concept-driven intellectual activities, including philosophical and metaphilosophical reflections, to take into serious consideration the phenomenon of conceptual change. An important consequence of this conception, and of the analysis that generated it, is in fact that an adequate understanding of the dynamics of philosophical concepts is a prerequisite for analytic philosophy to develop a realistic and non-idealized depiction of itself and its activities. (shrink)

The primary sense of the word ‘hypothesis’ in modern colloquial English includes “proposition not yet settled” or “open question”. Its opposite is ‘fact’ in the sense of “proposition widely known to be true”. People are amazed that Plato [1, p. 1684] and Aristotle [Post. An. I.2 72a14–24, quoted below] used the Greek form of the word for indemonstrable first principles [sc. axioms] in general or for certain kinds of axioms. These two facts create the paradoxical situation that in many cases (...) it is impossible to translate the Greek form of the word using the English form: the primary sense of the word ‘hypothesis’ in modern colloquial English is diametrically opposed to one sense used by Plato and by his most accomplished student Given current colloquial English usage it is impossible to get the word hypothesis to carry the connotation of “settled truth” much less “axiomatic truth”. The ‘hypo-’ [under] in the Plato-Aristotle use of ‘hypothesis’ might carry the sense of “basis” or “foundational” as opposed to “less than usual or normal”. This paradox parallels the one pointed out by Robin Smith: it is impossible for the English word ‘syllogism’ to carry the meaning of its Greek form Aristotle intended. There are other cases as well: it is impossible for the English biological term ‘genus’ to carry the meaning of its Greek form the Greek genos refers to family as in our ‘genealogy’, not to “higher species” as in our ‘generic’. (shrink)

It has become commonplace within feminist theory to claim that women’s lives are constructed by multiple, intersecting systems of oppression. In this thesis, I challenge the consensus that oppression is aptly captured by the theoretical model of “intersectionality.” While intersectionality originates in Black feminist thought as a purposive intervention into US antidiscrimination law, it has been detached from that context and harnessed to different representational aims. For instance, it is often asserted that intersectionality enables a representational politics that overcomes legacies (...) of exclusion within hegemonic Anglo-American feminism. I argue that intersectionality reinscribes the political exclusion of racialized women as a feature of their embodied identities. That is, it locates the failure of political representation in the “complex” identities of “intersectional” subjects, who are constructed as unrepresentable in terms of “race” or “gender” alone. Further, I argue that intersectionality fails to supplant race- and class-privileged women as the normative subjects of feminist theory and politics. In Chapter One, I demonstrate that intersectionality illicitly imports unitary concepts of “race,” “gender,” and “class.” In Chapter Two, I argue that intersectionality lacks a theory of hierarchy: it is a “flat geography” which cannot capture vertical and horizontal lines of power. In Chapter Three, I explore the role of analogical reasoning in rendering racialized women invisible both as gendered and as racialized subjects in twentieth-century social movements. To concretize this argument, I turn to Simone de Beauvoir’s use of race-sex analogies to describe (white, bourgeois) “women’s” situation in The Second Sex. In Chapter Four, I advance a programmatic unified account of oppression. I suggest that the possibility of a unified theory (as opposed to an intersectional one) is intimated in the concrete articulation of race, class, and gender. My point of departure is a phenomenology of capitalism, which reveals that these are all fundamentally modes of exploitation and appropriation. In Chapter Five, I theorize how they are made visible (and invisible) on the body. I extend Frantz Fanon’s account of “epidermalization,” drawing upon the marxian concepts of “fetishism” and “mode of appearance” to elaborate four structures of gendered racialized perception: first, the “miscegenation taboo” structures perceptions of the “purity” of whiteness and the “polluting” effects of blackness. Whiteness, theorised as a “possessive investment” and as “property” is defined by the right to exclude. Second, the “episteme of tellable differences” produces the conviction that we can automatically “tell the difference” between a body placed in one “racial” or gender category, and another—while bodies that temporarily confound classification cause fear and consternation. Third, the “race/reproduction bind” names the axiomatic assumption that “race” is reproduced through (heterosexual) procreation and that “race” is, therefore, biologically inheritable. Finally, the “fear/criminalisation reflex” refers to the bidirectional equation of particular racialised-gendered bodies with crime, and of crime with those bodies; this a function of the discursive use of ‘crime’ as an alibi for “race’” the systemic racialisation of punitive carceral institutions, and the historical origins of “race” in transatlantic chattel slavery, which shaped perceptual-cognitive associations of freedom with whiteness and captivity with blackness. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:A Naturalized Context of Moral Reasoning1Elizabeth BaetenAmerican philosophy of the past century seems to have availed itself of the advances in science primarily under the rubric of philosophy of science, especially using physics as the exemplar of scientific inquiry and almost entirely in service of developing an adequate epistemology (and related logic). Though there has been some philosophical work using biological sciences as areas of inquiry, this is most (...) often a matter of investigating either the logic or content of the life sciences as it relates to that of physics or chemistry; for example, trying to determine the proper method and scope of reduction. Cognitive science has been a fruitful avenue for philosophy of mind, but in most cases the dominant model sees mind as “software” able to be understood independently of the process of evolution that led to the human brain.Very little work (until the past half decade) has used advances in the life sciences as fodder for philosophic speculation in areas such as ethics, aesthetics, metaphysics, and so on, though some subfields, like medical ethics, provide exceptions. American pragmatic naturalists, on the other hand, from the second half of the ninteenth century into the middle of the twentieth, insisted that the content of the life sciences was essential in understanding human nature. John Dewey, for example, thoroughly incorporated the premise of humans as biological organisms making our way in environments that must be navigated using natural powers and natural solutions to impediments to action. George Herbert Mead provides another example of a fully naturalized conception of human existence, especially as biological organisms in social interaction in various spheres.What I am particularly concerned with here is making sense of the moral sphere with a conception of the human subject as a product of evolution and both socially constituted and uniquely integrated in an environment (more [End Page 63] carefully—a related suite of environments). The beginning point of this re-framing is in Mead’s notion of the social constitution of human being. Most readers of Mead take up such constitution only in the arena of what Mead calls “significant gesture,” using spoken language, especially in propositional form, as exemplary and as providing the foundation for mind, self-consciousness, and so on. But Mead’s concept of sociality is much wider in scope than this; the concept is fundamental to his cosmology. Furthermore, Mead’s notion of sociality is closely linked to his claim that the emergence of true novelty is possible in a fully naturalized cosmos.Without exploring in greater depth Mead’s contribution to thinking about sociality as a precondition for the most fundamental natural processes,2 I would like to use a broadened version of this to frame some contemporary work in biology, ecology, and cognitive science as they relate to human existence, especially in terms of how we may think productively about the moral sphere.In earlier work, I noted that there is a ubiquitous premise in Western moral theories that I believe is mistaken—or at least worthy of serious reconsideration. Most moral theory takes as axiomatic that whatever feature makes us uniquely human is the same feature that, when perfected, makes us moral. That is, that being “good” at being human makes us “good” humans. This is obviously so for Aristotle, insofar as it is rationality that is our special ergon, and it is using rationality well and beautifully that constitutes human virtue. But I think similar assumptions underlie much of moral theory, ancient and modern, and extend to contemporary work that takes language (or concept) use as peculiarly human and sees linguistic (or conceptual) analysis of moral claims as the proper domain of ethical theory.It seems that this presupposition, in part insisting that morality is uniquely human, is put in question if we take seriously evolution through natural selection and understand the human species to be as much a product of natural selection as any other species. There has been a good deal of ethological work done in the past several decades pointing out the protomoral capacities of other highly social animals, especially in those species to which we are most closely related (see, for example... (shrink)

This contribution is an essay of formal philosophy—and more specifically of formal ontology and formal epistemology—applied, respectively, to the philosophy of nature and to the philosophy of sciences, interpreted the former as the ontology and the latter as the epistemology of the modern mathematical, natural, and artificial sciences, the theoretical computer science included. I present the formal philosophy in the framework of the category theory (CT) as an axiomatic metalanguage—in many senses “wider” than set theory (ST)—of mathematics and logic, (...) both of the “extensional” logics of the pure and applied mathematical sciences (=mathematical logic), and the “intensional” modal logics of the philosophical disciplines (=philosophical logic). It is particularly significant in this categorical framework the possibility of extending the operator algebra formalism from (quantum and classical) physics to logic, via the so-called “Boolean algebras with operators” (BAOs), with this extension being the core of our formal ontology. In this context, I discuss the relevance of the algebraic Hopf coproduct and colimit operations, and then of the category of coalgebras in the computations over lattices of quantum numbers in the quantum field theory (QFT), interpreted as the fundamental physics. This coalgebraic formalism is particularly relevant for modeling the notion of the “quantum vacuum foliation” in QFT of dissipative systems, as a foundation of the notion of “complexity” in physics, and “memory” in biological and neural systems, using the powerful “colimit” operators. Finally, I suggest that in the CT logic, the relational semantics of BAOs, applied to the modal coalgebraic relational logic of the “possible worlds” in Kripke’s model theory, is the proper logic of the formal ontology and epistemology of the natural realism, as a formalized philosophy of nature and sciences. (shrink)

It is axiomatic that the fuller and more integrated interpretation of scientific discoveries and data lies within the domain of the philosopher. This statement has all the more force when we come to deal with the problem of Life and its origins. In his book, Dr. Fothergill rightly takes for granted that eventually all life goes back to God for its origin, but his primary concern is the origin of life on the earth. Arguing that before we look for (...) the origin of life we must try to find out what life itself is, he examines the various theories of abiogenesis and points out that they all fail to find a real distinction between the living and the non-living. They all assume that fundamentally a living organism is nothing more than a complex physicochemical system in equilibrium. The proponents of these theories while readily admitting the enormous complexity of the organic molecules that take part in biological reactions, yet with incredible naiveté postulate that these have evolved from simpler peptides which in turn have been synthetised from simple inorganic molecules like carbon dioxide and ammonia in the primaeval oceans. While even fairly complex polypeptides have been built up in vitro, their synthesis from a mixture of inorganic chemicals has never been observed. (shrink)

The broader context for the formal darwinism project established by two of the commentators, in terms of reconciling the Modern Synthesis with Darwinian arguments over design and in terms of links to other types of selection and design, is discussed and welcomed. Some overselling of the project is admitted, in particular of whether it claims to consider all organic design. One important fundamental question raised in two commentaries is flagged but not answered of whether design is rightly represented by an (...) optimisation program, and another from one commentary of whether the coreplicon dissolves in the face of multi-generational imprinting. Calls for the project to be extended to design at levels above and below the individual are considered sympathetically, but judged impractical at the high level of abstraction of the project. All claims of substantive technical error are emphatically rejected. Close technical readings are welcomed that, among other things, represent the project as 'axiomatizing fitness'. The prospects for the project are set out in the light of this highly varied set of commentaries. (shrink)

Proponents of two axioms of biological evolutionary theory have attempted to find justification by reference to nonequilibrium thermodynamics. One states that biological systems and their evolutionary diversification are physically improbable states and transitions, resulting from a selective process; the other asserts that there is an historically constrained inherent directionality in evolutionary dynamics, independent of natural selection, which exerts a self-organizing influence. The first, the Axiom of Improbability, is shown to be nonhistorical and thus, for a theory of change through time, (...) acausal. Its perception of the improbability of living states is at least partially an artifact of closed system thinking. The second, the Axiom of Historically Determined Inherent Directionality, is supported evidentially and has an explicit historical component. Historically constrained dynamic populations are inherently nonequilibrium systems. It is argued that living, evolving systems, when considered to be historically constrained nonequilibrium systems, do not appear improbable at all. Thus, the two axioms are not compatible. Instead, the Axiom of Improbability is considered to result from an unjustified attempt to extend the contingent proximal actions of natural selection into the area of historical, causal explanations. It is thus denied axiomatic status, and the effects of natural selection are subsumed as an additional level of constraint in an evolutionary theory derived from the Axiom of Historically Determined Inherent Directionality. (shrink)

This volume comprises a selection of papers that were contributed to the 7th International Congress of Logic, Methodology and Philosophy of Science, which was held in Salzburg from the 11th - 16th July, 1983. There were 14 sections in this congress: 1. proof theory and foundations of mathematics 2. model theory and its applica ti on 3. recursion theory and theory of computation 4. axiomatic set theory 5. philosophical logic 6. general methodology of science 7. foundations of probability and (...) induction 8. foundations and philosophy of the physical sciences 9. foundati ons and phi 1 osophy of biology 10. foundations and philosophy of psychology foundations and philosophy 11. of the social sciences 12. foundati ons and philosophy of linguistics 13. history of logic, methodology and philosophy of science 14. fundamental principles of the ethics of science In each section, three or four invited addresses were given, which will be published in the Congress Proceedings (Ruth Barcan Marcus, Georg J. W. Dorn and Paul Weingartner, eds. : Logic, Metho dology and Philosophy of Science VII. Proceedings of the Seventh International Congress of Logic, Methodology and Philosophy of v PREFACE Science, Salzburg, 1983. - Amsterdam, New York, Oxford: North-Holland Publishing 'Company, 1985. ) Every section with the exception of section 14 also contained contributed papers. (shrink)

A investigação de um domínio amplo da realidade, como a evolução dosseres vivos, pode dar origem a diferentes “teorias”, cada uma consoantecom uma particular perspectiva que se considere. Para que se proceda auma análise detalhada dos pressupostos e conceitos que baseiam umadeterminada visão, o método axiomático parece ser a melhor das opções.Neste artigo, são discutidas algumas teorias da biologia evolutiva de umponto de vista axiomático, mostrando-se de que forma se pode apresentarum “predicado de Suppes” para a teoria sintética da evolução, (...) comodetalhado em outro local . Estaformulação é utilizada, dentre outras coisas, para se discutir a noção deaptidão darwiniana, bem como para explorar as relações entre a teoriadarwiniana da seleção natural e a genética de populações.The investigation of a wide field of knowledge, as evolution of living beings,may originate different “theories”, each one acting as a particularperspective we have about the domain. In order to proceed a philosophicalanalysis of the underlying assumptions of a particular view, it seems thatthe use of the axiomatic method is still the better way. Here, we discuss some theories of evolutionary biology from an axiomatic point of view, bymeans of a Suppes predicate for the synthetic theory of evolution, alreadydetailed in MAGALHÃES and KRAUSE . This formulation is hereused, among other things, to deal with the concept of Darwinian fitness, soas to explore the relationships between Darwinian theory and populationgenetics. (shrink)

This paper is an attempt to reconstruct the history of genetic and evolutionary theories of same-sex sexual behavior using Imre Lakatos’ methodology of scientific research programs . Although distinct, those two programs are complementary. Whereas the genetic program maintains that homosexuality is genetically inherited, the evolutionary program attempts to explain how such a gene, which apparently reduces the reproductive fitness of its homozygous carrier, is maintained in the population. This appraisal reveals that the two research programs have not been empirically (...) progressive in the Lakatosian sense. I argue that this situation has arisen precisely because of inappropriate over-commitment to the respective hard cores of the two research programs. As adherence to such cores is essential for success in research programs, according to Lakatos, I argue that Lakatos’ account of science may be descriptively adequate but is normatively inadequate. I provide grounds for generalizing this case as follows: the MSRP may successfully capture the logic of axiomised sciences, such as physics, but applies poorly to most sciences, including biological and social sciences, which do not lend themselves to axiomatic organization. (shrink)

The fundamental concepts of the theory of knowledge ofKant—“transzendental”, “apriori”, and “aposteriori”, “konstitutiver” and “regulativer Vernunftgebrauch”, “Ding an sich”, “Erkenntnisvermögen”, etc.—are exemplified and examined by the modern theory of axiomatics. Therefrom essential consequences result in respect of modern theoretical biology as well as the elimination of usual misunderstandings about the relation between physics and biology in the philosophical system ofKant. The usual view thatKant would have admitted to physics only the causal-constitutive method of thinking, and on the contrary (...) would have admitted to biology merely a teleologic-regulative process, has to be rejected being entirely erroneous. — Then the theory of the “Ding an sich” is interpreted metabiologically, not metaphysically and finallyKants terminology of knowledge is explained biologically.Les notions fondamentales de la théorie de connaissance deKant — „transzendental”, „apriori” et „aposteriori”, „konstitutiver” et „regulativer Vernunftgebrauch”, „Ding an sich”, „Erkenntnisvermögen” etc. — sont mises en évidence et examinées par la théorie de l'axiomatique moderne. De là s'ensuivent des conséquences essentielles pour la biologie théorique moderne, ainsi que la suppression de malentendus en égard au rapport de la physique et de la biologie dans le système philosophique deKant. L'interprétation usuelle, selon laquelleKant aurait voulu accorder le raisonnement causal-constitutif à seule la physique, et, au contraire, n'aurait voulu accorder qu'un procédé téléologique-régulatif à la biologie, doit être rejetée comme étant entièrement erronnée. Ensuite, la doctrine de la „Ding an sich” est interprétée métabiologiquement au lieu de métaphysiquement, et enfin, la terminologie de la connaissance deKant est expliquée biologiquement. (shrink)

Primary object of interest of mathematicians can be identified as a „mathematical matter”, the concept analogous to „physical matter” or „biological matter”. The „mathematical matter” is the soil upon which mathematics grows. One can distinguish three levels of it: some abstract but not necessarily clear conceptions, operational notions (like number) but not necessarily openly defined, theories not necessarily axiomatic. The „mathematical matter” originates in the abstract reflection upon events and forms in time and space. Its important elements are notions (...) formed mostly in the process of idealization and/or abstraction. Once formed, notions usually evolve being, e.g., simplified or complexified. Mathematics is a mirror of the world, most abstract and therefore fundamental. Although it is a free activity of human mind, mathematics reflects some deep ideas (beauty, simplicity etc.) while most interesting notions come up in tension fields between pairs of poles: the notion of a function can be seen as a bridge connecting variability and immutability, while that of a limit – connecting finiteness and infinity. A fusion of freedom and internal restrictions leads to mathematics which is simple, beautiful and effective. (shrink)

The discovery of the importance of mereology follows and does not precede the formalisation of the theory. In particular, it was only after the construction of an axiomatic theory of the part-whole relation by the Polish logician Stanisław Leśniewski that any attempt was made to reinterpret some periods in the history of philosophy in the light of the theory of parts and wholes. Secondly, the push for formalisation - and the individuation of mereology as a specific theoretical field - (...) arise from several particular theories, first from biology and then from psychology. Mereological considerations were explicitly developed within the school of Brentano, by Brentano himself- starting from the problem of the unity of consciousness - and by his students, particularly Stumpl, Twardowski and the Gestaltists. The most complete result of this tradition is undoubtedly the third of Husserl's Logical Investigations, called "the single most important contribution to realist (Aristotelian) ontology in the modern period". (shrink)

Plato began it. After thinking about the nature of argument he concluded that the correct way of reasoning was the axiomatic way, and formulated the programme of axiomatization that Eudoxus and Euclid subsequently carried out. Since then the axiomatic method has been firmly established, not only as the method for mathematics, but as a paradigm to which all other disciplines should strive to be assimilated; and in this present century not only has axiomatization been carried through as completely (...) as it can be, but the most determined efforts have been made to wish hypotheticodeductive schemata on to biology, economics, and even history. (shrink)

In this dissertation, I present a novel account of the components that have a peculiar epistemic role in our scientific inquiries, since they contribute to establishing a form of coordination. The issue of coordination is a classic epistemic problem concerning how we justify our use of abstract conceptual tools to represent concrete phenomena. For instance, how could we get to represent universal gravitation as a mathematical formula or temperature by means of a numerical scale? This problem is particularly pressing when (...) justification for using these abstract tools comes, in part or entirely, from knowledge which is not independent from them, thus leading to threats of circularity. Achieving coordination between some abstract conceptual tools and the concrete phenomena that they are supposed to represent is usually a complex process, which involves several epistemic components. Some of these components eventually provide stable conditions for applying those abstract representations to concrete phenomena. It is in this sense of providing certain conditions of applicability that different philosophical traditions, as well as some contemporary reappraisals, view these components as constitutive or a priori. In this work, I present a new gradualist, contextualist, and relational approach to understand these constitutive components of scientific inquiry. It is gradualist inasmuch as the degree to which some component is constitutive depends on three quantifiable features: quasi-axiomaticity, generative potential, and empirical shielding. Since the quantification of these three features impinges on the history and practice of using these components in a scientific context, my approach is a contextualist one. Finally, my approach is relational in a double sense: first, it identifies ordinal relationships among epistemic components with respect to their constitutive character; second, these relationships are relative to a scientific framework of inquiry. After introducing my account and a classic example of constitutively a priori principles, i.e., Friedman’s (2001) analysis of Newtonian mechanics, I turn to my own case studies to demonstrate the advantages of my approach. Firstly, I discuss Okasha’s (2018) view of endogenization as a pervasive theoretical strategy in evolutionary biology and suggest that the constitutive character of the core Darwinian principles progressively increases with endogenization. Secondly, I apply a conceptual distinction between two varieties or scopes of coordination – general coordination and coordination in measurement – to Ohm’s work on electrical conductivity. This distinction allows me to pinpoint to what extent components along different dimensions (e.g., instrumentation, measurement, theorising, etc.) were constitutive of the forms of coordination which Ohm relied on. Thirdly, I discuss the epistemic function of the Hardy-Weinberg principle in the history and practice of population genetics. I assess this principle in terms of my account and identify approximation and stability as two components that are highly constitutive, in that they contribute to justifying its use in population genetics. Finally, applying my account to these case studies enables me to identify at least three qualitatively different types of constitutive components: domain-specific theoretical principles, material components, and domain-independent assumptions underlying reasoning abilities. In the light of my results, I draw some general conclusions on epistemic justification and scientific knowledge. (shrink)

This monograph suggests that theories of warfare and descriptions of the evolving character of war cannot be complete without first giving credit to the nature of war itself. Looking at varied portrayals of war from literary, academic, military, and civilian strategist perspectives, this monograph offers a redefinition of "war" as an investment in organized violence by parties interested in the extension, maintenance, or appearance of their power over an unspecified time, with an unknowable risk, for an uncertain reward. In drawing (...) an analogy to painting, it suggests that "choice" is the underlying axiomatic theme of war, and it that is replayed and adapted at every scale of warfare like a classical fugue. From there, this monograph pierces the interior of Clausewitz's "trinity" description of war, and proposes that there are still more universal ways to describe conflict's breadth, depth, and context. This argument concludes that war is better understood when it is described as a "clash of the trinities." An ecology of war is proposed, in which fundamental components comprising fuel, biology, and interactions constitute a network or system undergoing entropy. It is this sense of entropy (a tendency toward social and political discontinuity and disorder) that chiefly describes war in all its varied guises and explains the political, social, and military efforts to avoid them, corral them, plan them, or fight them. (shrink)

Until the late 19th century scientists almost always assumed that the world could be described as a rule-based and hence deterministic system or as a set of such systems. The assumption is maintained in many 20th century theories although it has also been doubted because of the breakthrough of statistical theories in thermodynamics (Boltzmann and Gibbs) and other fields, unsolved questions in quantum mechanics as well as several theories forwarded within the social sciences. Until recently it has furthermore been assumed (...) that a rule-based and deterministic system was also predictable if only the rules were known, but this assumption has now been undermined by modern chaos-theory describing rule-based and deterministic, but unpredictable systems, while catastrophe-theory delivers a set of types describing various kinds of instability and conditions for the stability of a given system. Hence the main trait in the theoretical development in the 20th-century science can be described as a basic modification and limitation of some of the fundamental and strong assumptions forwarded in the previous epochs of modern science. Ironically, the very same process has been a process in which the human capacity to intervene in nature has expanded dramatically and mainly with the help of the very same theories, and not least because they allow nature to be described and made manipulable on a lower level and a more fine-grained scale. While the overall theoretical consistency between the various theories has gone, the reach of human intervention in nature has increased based on quite new dimensions whether in the area of physics (e.g.: energy technologies, chemical technologies, nanotechnologies etc.) or biology (ge¬netic manipulation) or in the area of psychology, sociology and culture (artificial simulations of mental processes, new means of communication, implying changes in the social infrastructure and cultural behaviour etc.). While some of these changes and new conditions can be reflected from within the conceptual framework of rule-based systems, albeit more complex than formerly recognized, others seem to give rise to the question of whether there are »systems« and relations between different systems in the world which are not rule-based? For instance, it seems to be obvious that the notion of instability represents a major conceptual break with former theories of rule-based systems, as the stability of the latter is an axiomatically given property implied in the very notion of rule-based systems, while instability can only be the result of external influence which should be explained as the result of another rule-based sy¬stem. While there are no difficulties implied concerning the stability of rule-based systems, the notion of unstable states of a system raises the question of how there can be a system at all if there are no invariant stabilising principles? This is the first question which I will address. And I shall do so by taking two examples of such systems as my point of departure. The first example will be the computer and the second will be ordinary language. In both cases I will argue that the stability of these systems (which are both defined by the existence/presence of human intentions) are provided by the help of - differently organised - redundancy functions which both allow the maintenance of systems in unstable macro-states, suspension of previous rules, underdetermination and overdetermination and generation/emergence/creation of new rules more or less independent of previous rules by the help of optional recursions to the permanently accessible underlying levels as for instance the level of binary representation in computers. Since the notion of redundancy is both controversial as such and often avoided, the concept is discussed (as defined in Claude Shannon's mathematical theory of information and in the semiotic framework of J. J. Greimas) and leading to a more general definition in which the redundancy functions serve to overcome noisy conditions, but at the cost of rule-based stability, determination, and predictability. A second question will be how the notion of rule-generating systems relates to the notion of anticipatory systems and it will be argued that rule-generating systems share some features with an¬ticipatory systems and that the former from a certain viewpoint can be seen as a subclass of the latter, although anticipative features are not necessarily a part of the definition of rule-generating systems. On the other hand, it will be discussed whether anticipatory systems which are not rule-generating systems can exist and it will be argued that the capacity to anticipate is strongly limited if it is not part of a rule-generating system. Therefore, it is concluded that the most powerful anticipatory systems need to be rule-generating systems. (shrink)

This a special issue collecting papers on the philosophy of logic, written by some young Romanian philosophers, on a variety of topics like the grammar of first-order logic and the axiomatization of evolutionary biology.

We identify new, rather serious, physical and mathematical inconsistencies of the current formulation of noncanonical or nonunitary string theories due to the lack of invariant units necessary for consistent measurements, lack of preservation in time of Hermiticity-observability, and other shortcomings. We propose three novel reformulations of string theories for matter of progressively increasing complexity via the novel iso-, geno-, and hyper-mathematics of hadronic mechanics, which resolve the current inconsistencies, while offering new intriguing possibilities, such as: an axiomatically consistent and invariant (...) inclusion of gravity, the reduction of macroscopic irreversibility to the most primitive level of vibrations of the universal substratum (ether), or the treatment of multi-valued, irreducible, biological structures. We then identify three corresponding classical formulations of string theories for antimatter via the novel anti-isomorphic isodual mathematics. We finally outline the intriguing features of the emerging new cosmologies (including biological structures, as it should be for all cosmologies), such as: universal invariance (rather than covariance) under a symmetry isomorphic to the Poincaré group and its isodual; equal distributions of matter and antimatter in the universe (as a limit case); continuous creation; no need for the missing mass; significantly reduced dimensions; possibility of experimental identification of antimatter in the universe; identically null total characteristics of time, energy, linear and angular momentum, charge, etc.; and other intriguing features. (shrink)

The most majestic scientific achievement, of this century in mathematical beauty, axiomatic consistency, and experimental verifications has been special relativity with its unitary structure at the operator level, and canonical structure at the classical levels, which has turned out to be exactly valid for point particles moving in the homogenenous and isotropic vacuum (exterior dynamical problems). In recent decades a number of authors have studied nonunitary and noncanonical theories, here generally calleddeformations for the representation of broader conditions, such as (...) extended and deformable particles moving within inhomogeneous and anisotrophic physical media (interior dynamical problems). In this paper we show that nonunitary deformations, including, q-, k-, quatum-, Lie-isotopic, Lie-admissible, and other deformations, even thoughmathematically correct, have a number of problematic aspects ofphysical character when formulated on conventional spaces over conditional fields, such as lack of invariance of the basic space-time units, ambiguous applicability to measurements, loss of Hermiticity-observability in time, lack of invariant numerical predictions, loss of the axions of special relativity, and others. We then show that the classical noncanonical counterparts of the above nonunitary deformations are equally afflicted by corresponding problems of physical consistency. We also show that the contemporary formulation of gravity is afflicted by similar problematic aspects because Riemannian spaces are noncanonical deformations of Minkowskian spaces, thus having noninvariant space-time units. We then point out that new mathematical methods, calledisotopies, genotopies, hyperstructures and their isoduals, offer the possibilities of constructing a nonunitary theory, known asrelativistic hadronic mechanics which: (1) is as axiomatically consistent as relativistic quantum mechanics, (2) preserves the abstract axioms of special relativity, and (3) results in a completion of the conventional mechanics much along the celebrated Einstein-Podolski-Rosen argument. A number of novel applications are indicated, such as a geometric unification of the special and general relativity via the isominkowskian geometry in which the two relativities are differentiated via the invariant basic unit, while preserving conventional Riemannian metrics, Einstein's field equations, and related experimental verifications; a novel operator form of gravity verifying the axioms of relativistic quantum mechanics under the universal isopoincaré symmetry; a new structure model of hadrons with conventional massive particles as physical constituents which is compatile with composite quarks and with established unitary classifications; and other novels applications in nuclear physics, astrophysics, theoretical biology, and other fields. The paper ends with the proposal of a number of new experiments, some of which may imply new practical applications, such as conceivable new forms of recycling nuclear waste. The achievement of axiomatic consistency in the study of the above physical problems has been possible for the first time in this paper thanks to mathematical advances that recently appeared in a special issue of theRendiconti Circolo Matematico Palermo, and in other journals identified in the Acknowledgements. (shrink)

Photo by Hannah Busing on Unsplash INTRODUCTION Religion has long provided guidance that has led to standards reflected in some aspects of medical practices and traditions. The recent bioethical literature addresses numerous new problems posed by advancing medical technology and demonstrates an erosion of standards rooted in religion and long widely accepted as almost axiomatic. In the deep soul-searching that pervades the publications on bioethics, several disturbing and dangerous trends neglect some basic lessons of philosophy, logic, and history. The (...) bioethics discourse on medical aid in dying emphasizes similarity over previously recognized important distinguishing features. For example, it overplays a likeness between assistance in dying and the withdrawal of life-saving technology. In many bioethics’ topics, arguments based on a logical continuum are used to question the lines demarcating important moral differences. l. The Line Between Ethical and Not: Logic Based on Continuum Careful case selection, often either end of a continuum, allows the tearing down or ridiculing of many rules and codes across most professions and fields of interest. This situation holds true for traffic laws as well as medical ethics guidelines. It is relatively simple for those who desire to attack a particular viewpoint by selecting a case that makes that position seem untenable. In the ethics realm, good and bad medicine exist at opposite ends of an ethical continuum, with many practices lying in between. For example, much of medical ethics exists between the Nazi criminal physicians and the most sainted nurse or physician. A gradual progression occurred over less than two decades from a utilitarian position that supported limited euthanasia for those with certain mental illnesses to genocide. German society embraced a utilitarian ethic in which the value of human life no longer was intrinsic but instrumental.[1] Many morally significant points on a continuum were then ignored as the misguided utilitarian policy rampantly continued. A point in the continuum to distinguish between ethically justifiable and that which is not can be difficult to identify compared to the two extremes. This continuum is not unique to ethics but can be applied to almost any other aspect of human life and endeavor. Between a severely ill schizophrenic person and a superbly well-adjusted individual, there is a continuum of mental and psychological function. The existence of a continuum should not paralyze thinking and prevent us from drawing lines and identifying moral differences based on objective criteria as well as moral philosophy. Yet, by focusing on a continuum, many bioethicists use logic to disregard dividing lines between an "ethical" and an "unethical" act. Unfortunately, sometimes bioethicists draw revolutionary conclusions that would change the scope of medical practices which is accepted as ethical. There are many examples of similar shifts on the continuum. Many authors argue for the ethical permissibility of abortion by pointing out that the human fetus is no different in various characteristics, one arguing it is as like an ape or chick as it is like a person,[2] and does not achieve unique human and individual characteristics until well into the first year of life.[3] While human fetuses arguably do not have certain distinctive qualities of personhood, most people shy away from the logical next conclusion: permitting infanticide. For example, Joshua Lederberg condemns infanticide, in the face of biological illogic, because of our emotional commitment to infants, to me, a relatively weak explanation. Sir Francis Crick suggests we might consider birth at two days of life in order to decide whether an infant is a "suitable" member of society.[4] Giublini and Minerva suggest that infanticide should be permissible since late pregnancy abortions are permissible, arguing there is no significant difference between a fetus just before birth and an infant just after birth.[5] Clearly the continuum approach would allow for subjective arguments in favor of later infanticide at other points many days post-birth. Years ago, with a cynical tone, I mentioned infanticide as a further step on the continuum beyond abortion, and I was rightly shouted down as being deliberately provocative to assert the logic would ever stretch so far. While it is not an accepted mainstream position, the movement in academic settings from widespread condemnation to limited possible acceptance of infanticide has taken place in an incredibly short time. Public opinion and medical opinion in these areas have shifted dramatically in a short time. In another area, from a biological and chemical point of view, there is a continuum from man down to a single carbon atom. Yet, it would not seem logical to ignore the emotional differences, the meaning of personhood, or the moral distinction between killing an insect and killing a person. ll. A False Continuum: Medical Aid in Dying I assert that there has been an erosion of ethical guidelines in recent years attributable to using continuums to camouflage important distinctions. James Rachels’ work on active and passive euthanasia, which contends that the two are ethically identical, exemplifies that logic.[6] He illustrates this thesis, using a continuum to compare different scenarios with like consequences as morally equivalent, by comparing the deliberate drowning of a child with a deliberate failure to rescue a drowning child when easily able to do so. The author's comparison proposes that since much of the medical profession has already made peace with withholding treatment in order to hasten death, consistency inexorably demands that we permit active euthanasia as well.[7] When permission for active euthanasia was first introduced, it was limited exclusively to patients suffering severely from an intractable, incurable, and irreversible disease. These guidelines have been continuously eroded. There is now a substantial serious consideration for permitting active euthanasia of healthy elderly individuals who feel that they have completed their lives and are "tired of living."[8] There are many moral and factual differences along the ethical continuum. In human life, there is a difference between a live baby and a fetus, between a viable fetus and one that is not, between a fetus and a zygote, and between a zygote and a sperm cell. Similarly, there is a difference between pulling a trigger to kill someone and not interfering in preventing his death, which is reprehensible though both may be. There is a difference between not resuscitating an 80-year-old man with cancer when his heart stops and injecting him with a fatal dose of potassium chloride. I argue that an overt act of taking life repels civilized human beings is to be commended and encouraged as the reverence for human life or even for just a moment of human life is one of the great contributions of our civilization. CONCLUSION As an orthodox Jew, I feel that divinely inspired guidelines that have stood the test of centuries shape my beliefs, and such guidelines contradict medical aid in dying. I cannot speak to the viewpoint of those who do not access religion in defining their moral stance, nor do I implicate them in the current bioethics' trends, as I am not aware of the personal role of religion in the lives of most such authors. While many nonreligious people have a firm philosophical grounding and oppose medical aid in dying, I suggest that in the absence of any religious or other absolute standards, developing logically defensible ethical guidelines may be challenging. At the least, religion may play a role in defining the points on the continuums that are ethically meaningful and refuting the trending beliefs that if the endpoint is the same, allowing different methods of arriving at that end are somehow ethically equal. The continuum of ways death may result does not negate analysis of whether death is brought about in ways that recognize the importance of life. The German philosopher Hans Jonas said, "It is a question whether without restoring the category of the sacred, the category most thoroughly destroyed by the scientific enlightenment, we can have an ethics able to cope with the extreme powers that we possess today and constantly increase and are compelled to use."[9] While countries vary on the role of religion in policy, with many emphasizing freedoms of religion, a recent position paper released by a group of Jewish, Christian, and Moslem leaders suggested the need for agreement on the unique sanctity of human life.[10] I would recommend that such a document serve as an example of consensus on critical foundational bioethical guidelines for democratic secular societies. - [1] Alexander L Medical science under dictatorship. New England Journal of Medicine, 241, p39-47 DOI10.1056/NEJM194907142410201 [2] Lederberg J. A geneticist looks at contraception and abortion, Annals of Internal Medicine 67, sup 2, 25-27. https:/doi.org/10.7326/0003-4819-67-3-25 [3] Ibid. [4] Editorial, Sociology: Logic of biology. Nature 220, 429 https://www.nature.com/articles/220429b0 [5] Giublini A Minerva F After-birth abortion: why should the baby live. J Med Ethics 39, 261- [6] Rachels J Active and passive euthanasia. New England Journal of Medicine 292, 78-80 [7] Ibid. [8] Cohen-Almagor R Euthanizing people who are "tired of life". in Euthanasia and Assisted Suicide-Lessons from Belgium. Ch 11 of Euthanasia and Assisted Suicide, Cambridge University Press pp173-187. 2017 and DOI; https://doi.org/10.1017/9781108182799.012 [9] Hans Jonas, Technology and Responsibility: Reflections on the New Tasks of Ethics, 1972, found as Chapter IX, Philosophical Essays, 1980. https://inters.org/jonas-technology-responsability [10] A position paper of the Abrahamic Monotheistic religions on matters concerning the end-of-life. Vatican Press 28 October 2019 https://press.vatican.va/content/salastampa/en/bollettino/pubblico/2019/10/28/191028f.html. (shrink)

In the light of contemporary allelopathic research, the intuitively based statements of the early botanists stand up surprisingly well. The walnut tree is now understood to affect the growth of neighboring plants via juglone leached from the leaves, roots, and fruits.118 The replant or soil sickness problem of peach orchards has been related to the toxigenic breakdown of amygdalin, a constituent of peach roots.119 The declining yield of many crop species grown under continuous monoculture has been linked to the accumulation (...) of allelopathic substances in the soil, especially through the mediation of microorganisms.120 Numerous plants cited by de Candolle as being injurious, such as Erigeron,121 thistle (Cirsium),122 flax (Linum),123 and various crucifers (such as Brassica nigra),124 have been found to posses marked allelopathic activity. Over fifty years before the discovery of rhizobia, de Candolle considered the excretory material of legumes to be beneficial to cereals.125Modern reviews of allelopathy commonly credit de Candolle with an insight that was not equaled by the technology of his era.126 In fairness to his detractors, his toxin theory of plant interactions was largely the by-product of an outdated and misconstrued notion of plant nutrition. His critics and most earlier botanists had similarly erred in seeking a single factor responsible for plant growth, much as had the alchemists sought the legendary philosopher's stone. Taking all this into account and considering the forceful personality of Liebig, one can readily appreciate how, 130 years ago, Liebig's theories preempted and stifled those of de Candolle.Today, with modern techniques of plant physiology and soil biochemistry, allelopathy has been shown to be a real but subtle factor in the dynamics of natural and agricultural plant communities. It is unfortunate that the single-mindedness characteristic of previous centuries still persists. The dichotomy between allelopathy and competition is exacerbated by the inherited bias toward the nutritional model of plant interaction fostered by Liebig, and is accentuated in the fact that in modern nutritional studies it is still basically unnecessary to consider plant-plant chemical interactions and their concomitant effects, whereas in allelopathic investigations the converse is regarded as axiomatic.In summary, de Candolle should not be seen as “a prophet crying in the wilderness,” as Fisher would have it.127 The bases of de Candolle's concept of allelopathy were the dubious experiments of Macaire and his own obsolete theory of plant nutrition. Despite this, modern experimental work indicates that allelopathy is important in many plant interactions. De Candolle seems to have been right, at least in part—but for the wrong reasons. (shrink)

Elsasser outlines in an informal but meticulous fashion an organismic biology which promises, in his opinion, to combine the best features of epigenetic vitalism and preformationist mechanism. Mechanistic reductionism is for Elsasser an unverifiable metaphysical hypothesis; i.e., if the postulate of infinite homogenous classes is dropped from the axiomatics of Van Neumann's proof that the state of any system is, in principle, Quantum Mechanically determinable, it becomes combinatorically obvious that biological systems and classes are radically inhomogenous [[sic]], a fact (...) which operationally bars the way to any complete reductionism. The door is thus opened to an open-ended theoretical biology in which all questions do not have a truth-functional equivalent answer according to the axioms and laws of the science, and prediction in the science becomes statistical in a nonabsolute way. Elsasser is a physicist with more than a casual acquaintance with biology and his argument benefits by his obvious expertise in both of these areas. Philosophically, however, he is a lightweight and relies, in particular, too much on the ontological ice that might be cut by operationalism. Theories are not verified in the stringent operational sense; they are confirmed in a way which is not logically tied to the requirement that all laws be inductively established. Elsasser, however, has so much to say on the problem of reductionism in biology that is of obvious value that the book is easily recommended over these caveats.—E. A. R. (shrink)