Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

This article reviews the contributions of the UN Convention on the Rights of Persons with Disabilities to the progressive development of both international human rights law and global health law and governance. It provides a summary of the global situation of persons with disabilities and outlines the progressive development of international disability standards, noting the salience of the shift from a medical model of disability to a rights-based social model reflected in the CRPD. Thereafter, the article considers the Convention's structure (...) and substantive content, and then analyzes in specific detail the particular contributions of the Convention to health and human rights law and global health governance. It concludes with an exploration of the potential implications of the CRPD's innovations for some of the most pressing issues in global health governance, including the Convention's contributions to the principle of participation in decision-making. (shrink)

The United Nations Convention on the Rights of Persons with Disabilities, adopted on December 13, 2006, and entered into force on May 3, 2008, constitutes a key landmark in the emerging field of global health law and a critical milestone in the development of international law on the rights of persons with disabilities. At the time of its adoption, the U.N. High Commissioner for Human Rights heralded the CRPD as a rejection of the understanding of persons with disabilities “as objects (...) of charity, medical treatment and social protection” and an embrace of disabled people as “subjects of rights.”The text of the Convention itself, and the highly participatory process by which it was negotiated, signal a definitive break from previous international approaches that focused on disability within a medical model framework. In contrast to traditional approaches, the CRPD embraces a social model of disability, concentrating the disability experience not in individual deficiency, but in the socially constructed environment and the barriers that impede the participation of persons with disabilities in society. (shrink)

A formalism is developed which admits particles faster than light and reference frames faster than light and as fast as light. It is fully consistent with the physical principles of special relativity. The necessity of introducing imaginary quantities does not arise. It does not encounter any difficulties with the principle of causality if it is reasonably interpreted.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 42.2 (2004) 232-233 [Access article in PDF] Giuseppina D'Oro. Collingwood and the Metaphysics of Experience. New York: Routledge, 2002. Pp. xi + 179. Cloth, $80.00. There is a resurgence of interest in Collingwood among philosophers and political theorists in the English-speaking world. One of the scholars leading this resurgence is Giuseppina D'Oro, whose fine monograph on Collingwood's metaphysics and epistemology appears in the (...) series "Routledge Studies in Twentieth-Century Philosophy." D'Oro's prose is lucid and tightly argued: her analyses of the problems that concerned Collingwood, as well as her reinterpretations and supporting arguments, are a thoughtful model of clarity.Collingwood is generally ignored except by philosophers of art and history; D'Oro aims to reassess Collingwood's important metaphysical and epistemological views and raise awareness of them. Arguing that, when not ignored, these aspects of Collingwood's philosophy often have been misinterpreted, D'Oro supplies a reconstruction and defense of Collingwood's conception of philosophical thought. Admirably and insightfully, she contextualizes his concerns within the past three centuries of philosophy and also within influential contemporary discussions (addressing, for example, relationships to Locke, Hume, Kant, Prichard, Russell, Ryle, Ayer, James, Rorty, and Quine). D'Oro demonstrates that Collingwood provides crucial contributions to both the history of philosophy and contemporary debates.For D'Oro, Collingwood's key text is his An Essay on Philosophical Method (1933), which is concerned with the proper subject matter, method, and task of philosophy. This work, [End Page 232] with its distinction between philosophical and empirical concepts, introduces into Collingwood's metaphysics the Kantian element that D'Oro emphasizes to support her original interpretation. Collingwood's metaphysics, like Kant's, is described as a "descriptive metaphysics" or "metaphysics of experience" (2-3) which was intended to reform, not jettison, metaphysics. Conceptual rather than ontological, Collingwood's metaphysics is an epistemological project that reveals not the "structure of reality," but the "structure of experience" (2). According to Collingwood, all knowledge is based on presuppositions and conditioned by them; thus, metaphysics cannot be a presuppositionless "study of pure being" (3) or things-in-themselves. Rather, Collingwood's Kantian metaphysics aims to uncover the absolute presuppositions behind various aspects of experience, presuppositions that ground or make possible diverse forms of knowledge and that structure different domains of inquiry. D'Oro here argues intriguingly against a view of much Collingwood scholarship: that for the later Collingwood of An Essay on Metaphysics (1940), metaphysics is the study of the historically relative presuppositions adopted by diverse people of different historical eras or epochs, i.e., metaphysics entails historical relativism. Instead, D'Oro contends, metaphysics for Collingwood is the second-order study of the absolute presuppositons that provide the conditions for the possibility of disciplinary knowledge. Furthermore, she argues, this metaphysical view is consistent with An Essay on Philosophical Method. Contra some commentators, there is no "early" and "late" Collingwood, and the notion that he ultimately experienced a "radical conversion" (79) to historical relativism is false.Collingwood's metaphysics of experience entails that domains of inquiry such as art, religion, natural science, and history are governed by distinct presuppositions or a priori principles and thus provide complementary, not competing, accounts of reality. Hence, history deals with actions and presupposes that their causes are freely chosen reasons or motives; natural science deals with events and presupposes that they are caused by empirical regularities in nature. These presuppositional distinctions are philosophical and conceptual rather than empirical, and different areas of knowledge may address the same empirical objects in different ways.This truncated summary hardly does justice to the rich totality of D'Oro's book, much of which provocatively works out the implications of her reinterpretation. Among other things, she defends Collingwood against metaphysical realism, neo-empiricism, and logical positivism; addresses his idiosyncratic "'rehabilitation' of the ontological proof" (67); argues against the common view that his philosophy of history promotes "re-enactment" as a methodological procedure for historical practice; and explores his non-dualist and non-physicalist resolution of the mind/body problem.Perhaps... (shrink)

We argue for a novel view of suspending judgment properly--i.e., suspending judgment in an ex post justified way. In so doing we argue for a Kantian virtue-theoretic view of epistemic normativity and against teleological virtue-theoretic accounts.

First published in Essays: Second Series in 1844, Ralph Waldo Emerson’s “Experience” has long been considered an enigmatic touchstone of the Emersonian corpus. This essay seems to point to many difficult—and key—questions as to the aims and implications of Emerson’s literary style, intellectual methods, and philosophical inquiries. Conventionally viewed as evidence of a hinge in Emerson’s intellectual development from youthful innocence to middle-aged experience, this essay has often been understood as an arena for the contestation of Emersonian ideas about self-reliance, (...) philosophical idealism, and self-knowledge; as with ancient gladiatorial spectacles, not all of these ideas may walk out of the arena alive.1 .. (shrink)

In this paper I identify a fallacy. The fallacy is worth noting for practical and theoretical reasons. First, the rampant occurrences ofthis fallacy-especially at moments calling for careful thought-indicate that it is more pernicious to clear thinking than many of those found in standard logic texts. Second, the fallacy stands apart from most others in that it contains multiple kinds oflogical error (i.e., fallacious and non-fallacious logical errors) that are themselves committed in abnormal ways, and thus it presents a two-tiered (...) challenge to oversimplified accounts of how an argument can go bad. (shrink)

This essay examines the funeral sermon given by the Baptist theologian Andrew Fuller (1754–1815) for his friend and deacon Beeby Wallis in 1792 as a vantage-point from which to pursue reflection on Fuller’s concept of heaven and the beatific vision. The sermon has two main themes: the rest and rewards of those who die in Christ. The essay examines how Fuller interprets both of these phrases and then, looking at the rest of Fuller’s corpus, notes that ultimately God himself is (...) the believer’s reward. (shrink)

Introduction: Middle-Earth, The lord of the rings, and international relations -- Order, justice, and Middle-Earth -- Thinking about international relations and Middle-Earth -- Middle-Earth and three great debates in international relations -- Middle-Earth, levels of analysis, and war -- Middle-Earth and feminist theory -- Middle-Earth and feminist analysis of conflict -- Middle-Earth as a source of inspiration and enrichment -- Conclusion: international relations and our many worlds.

I think that to Lord Kelvin is attributed the saying that the scientific attitude to a thing, if you can't do anything else with it, is to measure it. This is the attitude I propose to adopt towards Time . The situation is to some extent analogous to the situation with regard to electricity . Science is unable to say what electricity is, and so it almost denies the word any entrance into a treatise on the subject. It replaces (...) it by the word charge , which is something that can be measured. It is important to avoid hypostatizing time into a thing-in-itself. Instead of trying to say what time is we try to find a way of measuring it. (shrink)

O presente trabalho tem o objetivo de conectar a teoria criada por Pierre Bourdieu sobre a violência simbólica e o texto de Audre Lorde, The use of anger: women responding to racism do seu livro Sister Outsider; demonstrando a importância do debate sobre a relação entre dominante e dominado a partir do viés racial, tema abordado por ambos autores em seus textos. Com este fito, pretendemos diferenciar os resultados objetivos do ódio, raiva e culpa, bem como o modo que as (...) agressões invisíveis repercutem na vida do oprimido. Tendo como foco o racismo na vida da “mulher de cor” que ainda nos dias de hoje, em uma pirâmide social, se encontram em desvantagem quanto aos demais indivíduos. Faz parte dos objetivos também trazer à tona a reação do oprimido como consequência natural dos séculos de silenciamento, privação e desumanização, analisando os mecanismos institucionais para pacificação social. (shrink)

From Patristic writings ample evidence can be gathered about the important part which hymn-singing held in Early Christianity. Until recently, however, Early Christian hymnography was known only from documents transmitting the text but not the music. The discovery and publication of a Christian hymn in Greek with musical notation was, therefore, bound to change the whole aspect of studies concerned with the history of Early Christian music. This happened, as is well known, in 1922 when, under No. 1786 of the (...) fifteenth volume of the Oxyrhynchus Papyri A. S. Hunt edited a fragment of a hymn, dating from the late third century, together with a transcript of the music by H. Stuart Jones. For the first time it became possible to realize what kind of music Greek-speaking Christians in Egypt sang in praise of the Lord. (shrink)

Um livro que reúne alguns dos mais representativos textos que moldaram o que podemos chamar pensamento feminista. Uma obra de referência capaz de oferecer um repertório fundamental para os estudos de gênero e também para o ativismo. "A missão deste livro é, portanto, a de mostrar o caminho no qual os conceitos centrais do pensamento feminista foram se desdobrando, sendo questionados e dando origem a novas formas de pensar e definir identidades, gênero, subjetividades e sexualidades. A sinalização desse longo processo (...) que constituiu o léxico feminista vai certamente facilitar o estudo das tendências teóricas e o avanço dos trabalhos acadêmicos e políticos no contexto atual", Heloisa Buarque de Hollanda. (shrink)

Los liberales de todas las épocas han concedido siempre una gran importancia a las ideas en la historia y, en ese sentido, Lord Acton no es ninguna excepción. Al contrario, defendió en sus escritos que las ideas son fuerzas históricas muy poderosas que mueven el mundo. Son las causas de los sucesos políticos y que, entre todas ellas, la más importante es la idea de libertad. Una idea moral entendida como libertad de conciencia de la que nacen todas las (...) demás. Precisamente, por el reconocimiento del protagonismo de las ideas en las sociedades humanas, se le considera hoy en día uno de los mayores exponentes de la disciplina Historia de las ideas políticas. Sin embargo, encontramos en el pensamiento histórico de Acton una serie de afirmaciones polémicas y contradictorias. Reconoce la imperfección de nuestro conocimiento, la complejidad de la historia y de las ideas que contribuyen a explicarla, a la vez que hace del historiador un juez inflexible, objetivo e imparcial que ha de juzgar, no sólo los hechos históricos y las ideas que los provocaron, sino también a los historiadores que los narraron. _ _. (shrink)

House of Lords ruling on assisted dyingIn July 2009, the House of Lords ruled that the Director of Public Prosecutions must produce clear guidelines on the prosecution of those who help friends or relatives travel abroad for assisted suicide. 1 As previously reported here, both the High Court and Court of Appeal had rejected Debbie Purdy’s case before it reached the Lords.2 As a person with primary progressive multiple sclerosis, she had asked the court to rule that her husband would (...) not face prosecution if he accompanied her to Switzerland if she decides to end her life. 3By requiring the DPP to publish offence-specific guidelines about the circumstances in which a prosecution would be brought, the law lords did not go so far as to assert a right to assistance in dying by legalising assisted suicide. It was reiterated that any change to the criminal law against aiding and abetting suicide remained a political matter for Parliament. The Lords did, however, acknowledge that the right to privacy, and the associated right to autonomy, was potentially infringed by the absence of a transparent policy about those who are competent and terminally ill, or severely and incurably disabled, and who need help to travel abroad for assisted dying. The five law lords unanimously agreed that Ms Purdy’s right to a private life, as protected by article 8 of the European Convention on Human Rights, included the right to clarity regarding the exercise of the DPP’s discretion as to whether or not to prosecute.Following the Lords’ ruling, the DPP, Keir Starmer, confirmed that the new guidance would apply to all acts of assisted suicide, those taking place within and outside of the jurisdiction.4 He then published an interim policy for wide consultation in September 2009, and is expected to produce the final policy in …. (shrink)

1 My first teacher of philosophy, at what is now Rhodes University in South Africa, was Arthur R. Lord, a man who deserves to be well known, though today few people will ever have heard of him. He was himself a pupil of J.A. Smith and E.F. Carritt at Oxford in the early years of this century, during the heyday of British Idealism. In 1911 he won the Green Moral Philosophy Prize with a voluminous dissertation on the passions, which (...) I read in typescript when I was a student, but which was never published and disappeared after his death in 1940. (shrink)

1 My first teacher of philosophy, at what is now Rhodes University in South Africa, was Arthur R. Lord, a man who deserves to be well known, though today few people will ever have heard of him. He was himself a pupil of J.A. Smith and E.F. Carritt at Oxford in the early years of this century, during the heyday of British Idealism. In 1911 he won the Green Moral Philosophy Prize with a voluminous dissertation on the passions, which (...) I read in typescript when I was a student, but which was never published and disappeared after his death in 1940. (shrink)

First published in 1970, Bernard E. Jones’s selection of Gifford lectures includes excerpts from the writings of over ninety scholars who occupied a Gifford Chair between 1888 and 1968. Lord Gifford had asked his lecturers to be ‘honest to God’, insisting that they should be ‘earnest enquirers after truth’ and had always envisaged the lectures being published. Dr Jones’s anthology is arranged under headings suggested by phrases from Lord Gifford’s will. The selection, which includes names such as William (...) James, A.N. Whitehead, Temple, Barth, Brunner, Bultmann, Niebuhr and Tillich, was made in such a way that the reader would be able to really grasp what natural theology is about. Bernard Ewart Jones served as a Methodist minister, before being appointed to the Lewins Chair of Philosophy at his old college, Hartley Victoria, Manchester. He was awarded a doctorate by the University of Leeds in 1966 for his thesis on ‘The Concept of Natural Theology in Gifford Lectures’. (shrink)

First published in 1970, Bernard E. Jones’s selection of Gifford lectures includes excerpts from the writings of over ninety scholars who occupied a Gifford Chair between 1888 and 1968. Lord Gifford had asked his lecturers to be ‘honest to God’, insisting that they should be ‘earnest enquirers after truth’ and had always envisaged the lectures being published. Dr Jones’s anthology is arranged under headings suggested by phrases from Lord Gifford’s will. The selection, which includes names such as William (...) James, A.N. Whitehead, Temple, Barth, Brunner, Bultmann, Niebuhr and Tillich, was made in such a way that the reader would be able to really grasp what natural theology is about. Bernard Ewart Jones served as a Methodist minister, before being appointed to the Lewins Chair of Philosophy at his old college, Hartley Victoria, Manchester. He was awarded a doctorate by the University of Leeds in 1966 for his thesis on ‘The Concept of Natural Theology in Gifford Lectures’. (shrink)

Classic Edward Said´s term Orientalism was widely applied to those narratives and story-telling oriented to deride, subordinate and domesticate the “Non-Western Other”. Over centuries, Europe has developed an imperial matrix that is finely enrooted in an uncanny long-dormant paternalism where “the Other” was treated as a child to educate. The European expansion was ultimately feasible according to two combined factors. The knowledge productions by the hands of scientists occupied a great position in the entertainment of global readerships, and of course, (...) the literary fiction embodied in the figure of travel writing. This literary genre was mainly marked by the presence of a European adventurer who launched to colonize an unknown world. Travel writings spoke us of the native language of travelers who interrogated furtherly the natives. The present paperwork centers on what Derrida dubbed as “the axiom of hospitality” which means the power of language to control and domesticate the “Other”. The lingua franca not only represents the language of empire but also from the lords. In this way, world Language plays a leading role in giving a great cosmology of the surrounding world as well as legitimating the imperial expansion. (shrink)

In this article, I analyze how the Harry Potter novels bring to awareness two fundamental aspects of the human condition: the importance of one’s choices and the inevitability of one’s mortality. These are highlighted through the contrast of the characters of Harry Potter and Lord Voldemort.

Challenged by Lord Kelvin's claims that earth and sun were too young to give evolution sufficient time to do its work, especially in the human case, where care for the weak blunts the edge of natural selection, Darwin leaned on Lamarckian thoughts to accelerate the process. The mental and moral traits crowning human distinctiveness, he urged, arose through sexual selection. But promiscuity, infanticide, early betrothals, and female drudgery undermined these effects in “savage races.” In the inevitable decline and ultimate (...) extinction of the “melanin races” Darwin believed he could observe human evolution underway before his eyes. (shrink)

Growing evidence suggests that natural environments – whether in outdoor or indoor settings – foster psychological health and physiological relaxation, indicated by increased wellbeing, reduced stress levels, and increased parasympathetic activity. Greater insight into differential psychological aspects modulating psychophysiological responses to nature-based relaxation videos could help understand modes of action and develop personalized relaxation interventions. We investigated heart rate variability as an indicator of autonomic regulation, specifically parasympathetic activity, in response to a 10-min video intervention in two consecutive studies as (...) well as heart rate. We hypothesized that a nature-based relaxation video elicits HRV increase and HR decrease, with response magnitude being affected by aspects of early life adversity and trait mindfulness. In Study 1, N = 60 participants watched a relaxation video intervention depicting different natural scenery. We analyzed changes in HR and respiratory sinus arrhythmia as a standard HRV measure, both based on 3-min segments from the experimental session, in multiple growth curve models. We found a decrease in HR and increase of RSA during the video intervention. Higher paternal care and lower trait mindfulness observing skills were associated with higher RSA values before but not during video exposure. In Study 2, N = 90 participants were assigned to three video conditions: natural scenery from Study 1, meditation video, or short clip from “The Lord of the Rings.” Again, HR decreased, and RSA increased during video segments, yet without expected group differences across different video types. We found higher parental care and lower parental overprotection to predict higher RSA at different times during the experiment. Interestingly, lower paternal overprotection predicted overall higher RSA. These results suggest a generic relaxation effect of video interventions on autonomic regulation that we discuss in light of different theories mapping restorative effects of natural environments. Further, psychological characteristics like aspects of early life adversity and trait mindfulness could contribute to individual differences in autonomic regulation. This study contributes to a better understanding of autonomic and psychological responses to relaxation videos. (shrink)

“…we must move into theological anthropology if we are to do justice to the wisdom literature. In the Old Testament man can be defined in terms of his relationship to the Lord as his saviour, creator, sustainer. The working out of these ideas is not possible apart from the concern of Old Testament wisdom…”.

Andrew Marr has built this masterful study of Mutio Oddi on a set of ironies. He begins with a bitter blow of fortune: Oddi, in the middle of an apparently promising life as mathematician and architect in his native Urbino, had fallen afoul of his lord the Duke, accused of participating in a plot to depose him. After years of apparently unjust imprisonment, he was released in 1610, but into exile. Yet Oddi managed to recast his career in Milan (...) and then in Lucca, building upon a varied set of skills, and even returned eventually to Urbino. That varied set of skills had resulted from yet another, earlier, set of reversals and recoveries: he had turned to mathematics only after first training as an artist in the studio of Federico Barocci, a field he had been forced to abandon due to problems with his eyesight. Oddi was widely respected in his day, not only for his achievements themselves but also for his persistence and ingenuity in overcoming such obstacles. Yet to modern historians of .. (shrink)

For thirty years at least, I have designated myself as a zoologist interested in the “philosophical aspects of biology”. But I have now to admit that not until within the last two or three years have I recognized that logic, particularly in its inductive aspect, is involved in such interest.For me as a zoologist with a predilection for natural history, observation has had a place of wide application and of implicit confidence. Until recently, I had rested in the supposition that (...) after all of the devices practiced by naturalists to insure certainty of their observations, nothing further was needed so far as the information and understanding they gained was concerned. I had gone ahead with my reasoning, my logic, with no more qualms about the trustworthiness of the “inductive” than of the “deductive” side of it. I had not taken seriously the assertion, made years ago in my hearing by an eminent philosopher, that no one can be a philosopher without being skeptical and critical of the use of his senses in getting knowledge. Latterly, however, I have come to see that traditional philosophers take themselves very seriously in such assertions. This realization has been due to the discovery that the recent advances in physics and mathematics have led most of the leaders in these fields to believe that observation and the inductive side of logic may be left where they were a hundred years ago. These scientists seem to be about where John Stuart Mill was in his effort to improve Lord Bacon's effort for a better understanding of both observation and induction. (shrink)