In lieu of an abstract, here is a brief excerpt of the content:Kennedy Institute of Ethics Journal 14.1 (2004) 47-54 [Access article in PDF] Ethical Guidelines for Human Embryonic Stem Cell Research*(A Recommended Manuscript) Adopted on 16 October 2001Revised on 20 August 2002 Ethics Committee of the Chinese National Human Genome Center at Shanghai, Shanghai 201203 Human embryonic stem cell (ES) research is a great project in the frontier of biomedical science for the twenty-first century. Be- cause (...) the research involves the use of human embryos, it triggers serious debate on ethical issues. Opponents consider the embryo to be an early form of human life that should be respected and not destroyed. However, the majority of scientists support embryonic stem cell research, believing that it offers good prospects for the treatment of diseases that have remained incurable until now and so will benefit humankind. The Ethics Committee of the Department of Ethical, Legal, and Social Implications of the Chinese National Human Genome Center at Shanghai seriously discussed the ethical debate initiated by embryonic stem cell research. We concluded that we should support the scientists of our country in actively carrying out human embryonic stem cell research for the noble cause of "medicine being a beneficent art." For the healthy and orderly development of human embryonic stem cell research in our country, we put forward the following recommended Ethical Guidelines for Human Embryonic Stem Cell Research as a reference for leaders, administrative departments, and related scientists. Preface Article 1. Human embryonic stem cells are the primitive cells that play the main role in the growth and development of a human body. These [End Page 47] primitive cells have the potential for infinite proliferation, self-renewal, and multi-directional differentiation. If scientists can discover the mechanism of differentiation of human embryonic stem cells, it will be possible to induce differentiation of human embryonic stem cells to form various types of human cells for clinical cell therapy. If human embryonic stem cell research can be integrated with modern biomedical engineering techniques, it also will be possible to make repair and replacement of human tissues and organs a reality. Article 2. There are two ways to classify human embryonic stem cells. One way is to classify them according to their potential for differentiation. There could be three kinds of stem cells: totipotent stem cells, pluripotent stem cells, and unipotent stem cells.A totipotent stem cell has the potential to develop into a whole individual. It can differentiate into the more than 200 cell types in the whole body, construct any tissue or organ of the body, and finally develop into a whole individual. The fertilized egg and the cleavage cells at the very early stage of embryonic development are totipotent stem cells.A pluripotent stem cell has the potential to differentiate into many cell types derived from the three embryonic layers. However, it has lost the capacity to develop into a complete organism.A unipotent stem cell is derived from the further differentiation of the pluripotent stem cell. It can differentiate only into one cell type such as a hematopoietic stem cell, neural stem cell, and others.The other way is to classify human stem cells according to their source. There could be two kinds of human stem cells: embryonic stem cells and tissue stem cells (also called adult stem cells). The former involves experimentation with embryos, which has serious ethical implications. Ethical issues associated with the latter are mainly expressed in the various opinions regarding the allocation of health resources. Article 3. Human embryonic stem cells are the group of cells called the blastocyst inner cell mass during the early stage of embryonic development. They are the main source of totipotent stem cells, and hence the focal and hot point in stem cell research. Studies on the clinical application of embryonic stem cells probably will involve use of the somatic cell nucleus transfer (SCNT) technique, which destroys the early human embryo. At present, the ethical and moral debate is very serious in human embryonic stem cell research regarding whether the research will develop... (shrink)

In this paper, I argue that brain death is death because, despite the appearance of genuine integration, the brain-dead body does not in fact possess the unity that is proper to a human organism. A brain-dead body is not a single entity, but a multitude of organs and tissues functioning in a coordinated manner with the help of artificial life support. In order to support this claim, I first lay out Hoffmann and Rosenkrantz’s ontological account of the requirements (...) for organismal unity and summarize an earlier paper in which I apply this account to the brain death debate. I then further support this ontological argument by developing an analogy between the requirements for the unity of an organism and the requirements for the unity of an orchestra. To do so, I begin by examining the role that a conductor plays in unifying a traditional orchestra, and then go on to show that the human organism functions like a traditional orchestra that relies upon a conductor for its unity. Next, I consider the conditions required to achieve orchestral unity in conductorless orchestras and show that, in contrast to simpler organisms like plants, the postnatal human organism lacks those conditions. I argue, in other words, that although conductorless orchestras do exist, the human organism is not one of them. Like a traditional orchestra without a conductor, the brain-dead body is not a unified whole. (shrink)

Conventional ethics of how humans should eat often ignore that human life is itself a form of organic activity. Using Henri Bergson’s notions of intellect and intuition, this chapter brings a wider perspective of the human organism to the ethical question of how humans appropriate life for nutriment. The intellect’s tendency to instrumentalize living things as though they were inert seems to subtend the moral failures evident in practices such as industrial animal agriculture. Using the case study (...) of Temple Grandin’s sympathetic cattle technologies, this chapter moves beyond animal welfare concerns to ground food ethics on the phenomenal character of food that is obscured by human activities of fabrication. (shrink)

This paper provides a new rationale for equating brain death with the death of the human organism, in light of well-known criticisms made by Alan D Shewmon, Franklin Miller and Robert Truog and a number of other writers. We claim that these criticisms can be answered, but only if we accept that we have slightly redefined the concept of death when equating brain death with death simpliciter. Accordingly, much of the paper defends the legitimacy of redefining death against (...) objections, before turning to the specific task of defending a new rationale for equating brain death with death as slightly redefined. (shrink)

Bettina Schöne-Seifert and Marco Stier present a host of detailed and intriguing arguments to the effect that potentiality arguments have to be viewed as outdated due to developments in stem cell research, in particular the possibility of re-setting the development potential of differentiated cells, such as skin cells. However, their argument leaves them without an explanation of the intuitive difference between skin cells and human beings, which seems to be based on the assumption that a skin cell is merely (...) part of a human organism, while an embryo is at some point a human organism. An appropriately designed concept of the human organism can explain the difference, but also has the potential of re-dividing the argumentative landscape along familiar lines. (shrink)

The biophilosophic justification for the idea that “brain death” is death needs to support two claims: that what dies in human death is a human organism, not merely a psychological entity distinct from it; that total brain failure signifies the end of the human organism as a whole. Defenders of brain death typically assume without argument that the first claim is true and argue for the second by defending the “integrative unity” rationale. Yet the integrative (...) unity rationale has fallen on hard times. In this article, I give reasons for why we should think of ourselves as organisms, and why the “fundamental work” rationale put forward by the 2008 President’s Council is better than the integrative unity rationale, despite persistent objections to it. (shrink)

Against the background of recent developments in neuroscience, the paper shows how, for Hegel, the theoretical, practical and evaluative functions of the mind are grounded in something like a natural normativity, based on the interaction of the body's inner world with the outer world. These forms of organic homeostasis are the basis for further kinds and levels of norms, and deviations from these norms, which result in mental pathologies, provide insights into the complexity of spirit.

Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of the human organism, distinguishing three fundamental circuits for its survival, which demonstrates and supports this statement, as a base for further development of the informational model of consciousness to a general informational model of the human organism. For this, it was examined the Informational (...) System of the Human Body and its components from the perspective of the physics/information/neurosciences concepts, showing specific functions of each of them, highlighting the correspondence of these centers with brain support areas and with their projections in consciousness, which are: Center of Acquisition and Storing of Information (CASI) reflected in consciousness as memory, Center of Decision and Command (CDC) (decision), Info-Emotional Center (IES) (emotions), Maintenance Informational System (MIS) (personal status), Genetic Transmission System (GTS) (associativity/genetic transmission) and Info Genetic Generator (IGG) related by the body development and inherited behaviors. The Info Connection (IC), detected in consciousness as trust and confidence can explain the Near-Death Experiences (NDEs) and associated phenomena. This connection is antientropic and informational, because from the multitude of uncertain possibilities is selected a certain one, helping/supporting the survival and life. The human body appears therefore as a bipolar structure, connected to two poles: information and matter. It is argued that the survival, which is the main objective of the organism, is complied in three main ways, by means of: (i) the reactive operation for adaptation by attitude; (ii) the info-genetic integration of information by epigenetic processes and genetic transmission of information for species survival, both circuits (i) and (ii) being associated to the information pole; (iii) maintenance of the material body (defined as informed matter) and its functions, associated to the matter pole of the organism. It results therefore that the informational system of the human body is supported by seven informational circuits formed by the neuro-connections between the specific zones of the brain corresponding to the informational subsystems, the cognitive centers, the sensors, transducers and execution (motor/mobile) elements. The fundamental informational circuits assuring the survival are the reactive circuit, expressible by attitude, the epigenetic/genetic circuit, absorbing and codifying information to be transmitted to the next generations, and the metabolic circuit, connected to matter (matter pole). The presented analysis allows to extend the informational modeling of consciousness to an Informational Model of Consciousness and Organism, fully describing the composition/functions of the organism in terms of information/matter and neurosciences concept. (shrink)

The question of when human life begins is critical in debates related to life issues. While there are a variety of proposals as to how an organism should be defined, many biologists and ethicists, particularly Catholics, have approached this issue by arguing that fertilization defines the beginning of a new organism. Examining the processes of fission and fusion, which take place before gastrulation, provides strong evidence for when human life beings and therefore how it should be (...) defined. Among the four dominant theories, regulative fission and fusion are the best explanations in terms of being the most consistent with the biological data. This explanation of twinning provides compelling evidence that fertilization is not a necessary condition for human generation, although it may be a sufficient condition. While fertilization generates the vast majority of human beings, additional human beings may rarely be generated during fission events. (shrink)

This article explores the evolution of human attention, focusing particularly on the phylogenetic and ontogenetic implications of the work of the American social psychiatrist Trigant Burrow. Attentional development is linked to the emergence of visual perspective, and this, in turn, is related to Burrow's notion of `ditention' (divided or partitive attention). Burrow's distinction between `ditention' and `cotention' (total organismic awareness) is examined, and, expanding on this, a threefold pattern of perceptual change is identified: prototention-->ditention-->cotention. Next, ditentive visual perspective is (...) related to binocular convergence, and the author makes use of the perspectivally ambiguous, `non-convergent' Gestalt figure known as the Necker Cube to illustrate cotention. The paper concludes by proposing that the shift from the currently pervasive ditentive pattern of awareness to a cotentive mode could have a salutary effect on human society. (shrink)

The organism-in-its-environment is recognized as the basic unit of analysis when dealing with living beings. This paper seeks to define the fundamental implications of the concept of the organism-in-its-environment in terms of the biosemiotic concept of human distributed cognition. Human distributed cognition in a biosemiotic context is defined as the ability of a self-referencing organism-in-its-environment to interact with its environment to satisfy its physiological and social needs to survive and sustain itself. The ontogenetic development of (...) the organism-in-its-environment serves as the backdrop to discover the implications of distributed cognition that have general applicability in organisms, but in this paper, are made relevant to human beings. (shrink)

In this book the editors invited prominent researchers with different perspectives and deep insights into the various facets of the relationship between reality and representation in the following three classes of agent: in humans, in other living beings, and in machines. -/- The book enriches our views on representation and deepens our understanding of its different aspects, a question that connects philosophy, computer science, logic, anthropology, psychology, sociology, neuroscience, linguistics, information and communication science, systems theory and engineering, computability, cybernetics, synthetic (...) biology, and bioinformatics biosemiotics. This book will be relevant to researchers in these fields. (shrink)

Although death statutes permitting physicians to declare brain death are relatively uniform throughout the United States, academic debate persists over the equivalency of human death and brain death. Alan Shewmon showed that the formerly accepted integration rationale was conceptually incomplete by showing that brain-dead patients demonstrated a degree of integration. We provide a more complete rationale for the equivalency of human death and brain death by defending a deeper understanding of the organism as a whole and by (...) using a novel strategy with shared objectives to justify death determination criteria. Our OaaW account describes different types of OaaW, defining human death as the loss of status as a human OaaW. We defend human death as similar to nonhuman death in terms of wakefulness, but also distinct in terms of the sui generis properties, particularly conscious awareness. We thereby defend the equivalency of brain death and human death using a resulting neurocentric rationale. (shrink)

Synthetic biology is an emerging discipline that aims to apply rational engineering principles in the design and creation of organisms that are exquisitely tailored to human ends. The creation of artificial life raises conceptual, methodological and normative challenges that are ripe for philosophical investigation. This special issue examines the defining concepts and methods of synthetic biology, details the contours of the organism–artifact distinction, situates the products of synthetic biology vis-à-vis this conceptual typology and against historical human manipulation (...) of the living world, and explores the normative implications of these conclusions. In addressing the challenges posed by emerging biotechnologies, new light can be thrown on old problems in the philosophy of biology, such as the nature of the organism, the structure of biological teleology, the utility of engineering metaphors and methods in biological science, and humankind’s relationship to nature. (shrink)

One of our most brilliant evolutionary biologists, Richard Lewontin has also been a leading critic of those--scientists and non-scientists alike--who would misuse the science to which he has contributed so much. In The Triple Helix, Lewontin the scientist and Lewontin the critic come together to provide a concise, accessible account of what his work has taught him about biology and about its relevance to human affairs. In the process, he exposes some of the common and troubling misconceptions that misdirect (...) and stall our understanding of biology and evolution.The central message of this book is that we will never fully understand living things if we continue to think of genes, organisms, and environments as separate entities, each with its distinct role to play in the history and operation of organic processes. Here Lewontin shows that an organism is a unique consequence of both genes and environment, of both internal and external features. Rejecting the notion that genes determine the organism, which then adapts to the environment, he explains that organisms, influenced in their development by their circumstances, in turn create, modify, and choose the environment in which they live.The Triple Helix is vintage Lewontin: brilliant, eloquent, passionate, and deeply critical. But it is neither a manifesto for a radical new methodology nor a brief for a new theory. It is instead a primer on the complexity of biological processes, a reminder to all of us that living things are never as simple as they may seem. (shrink)

The theory of the organism-environment system starts with the proposition that in any functional sense organism and environment are inseparable and form only one unitary system. The organism cannot exist without the environment and the environment has descriptive properties only if it is connected to the organism. Although for practical purposes we do separate organism and environment, this common-sense starting point leads in psychological theory to problems which cannot be solved. Therefore, separation of organism (...) and environment cannot be the basis of any scientific explanation of human behavior. The theory leads to a reinterpretation of basic problems in many fields of inquiry and makes possible the definition of mental phenomena without their reduction either to neural or biological activity or to separate mental functions. According to the theory, mental activity is activity of the whole organism-environment system, and the traditional psychological concepts describe only different aspects of organisation of this system. Therefore, mental activity cannot be separated from the nervous system, but the nervous system is only one part of the organism­environment system. This problem will be dealt with in detail in the second part of the article. (shrink)

This article focuses on Auguste Comte’s understanding of the organism–environment relationship. It makes three key claims therein: Comte’s metaphysical position privileged materiality and relativized the intellect along two dimensions: one related to the biological organism, one related to the social environment; this twofold materiality confounds attempts to reduce cognition to either nature or nurture, so Comte’s position has interesting parallels to the field of ‘epigenetics’, which sees the social environment as a causative factor in biology; and although Comte (...) ultimately diverged from the ‘postgenomic’ view in crucial ways, he remains a forerunner of the trend towards viewing the social and biological as entangled. Tending to these dimensions challenges the view that Comte is notable from a classical standpoint but ignorable from a contemporary one. It consequently invites renewed attention to his theoretical system. (shrink)

Most philosophers writing about personal identity in recent years claim that what it takes for us to persist through time is a matter of psychology. In this groundbreaking new book, Eric Olson argues that such approaches face daunting problems, and he defends in their place a radically non-psychological account of personal identity. He defines human beings as biological organisms, and claims that no psychological relation is either sufficient or necessary for an organism to persist. Olson rejects several famous (...) thought-experiments dealing with personal identity. He argues, instead, that one could survive the destruction of all of one's psychological contents and capabilities as long as the human organism remains alive--as long as its vital functions, such as breathing, circulation, and metabolism, continue. (shrink)

Written at the intersection of neurobiology, cognition, and political science, this work profoundly reinterprets human behavior. The recent findings in the field of human neuroscience have clear implications for transforming the so-called "behavioral sciences" and the way in which personal actions are perceived. White demonstrates that a sound appreciation of well-accepted neuroscientific positions requires that the study of human behavior focus on human capabilities and choices. This book is a compelling argument for a fundamental redirection of (...) thought away from a reductionist, deterministic approach to one viewing human actions as involving conscious choices and purposeful activities. (shrink)

While there is often good reason to study our world by abstracting properties from its parts to the point where the result can be modelled as mechanisms, there is no need to do so when humans are ….

Transhumanism is a loosely defined movement that has developed gradually over the past two decades. It promotes an interdisciplinary approach to understanding and evaluating the opportunities for enhancing the human condition and the human organism opened up by the advancement of technology. Attention is given to both present technologies, like genetic engineering and information technology, and anticipated future ones, such as molecular nanotechnology and artificial intelligence.

The present article is an attempt to bring together the development of mental activity and consciousness in the framework of the organism-environment theory (Jarvilehto, 1998a, 1998b, 1999); the main question is how the development of mental activity and consciousness can be formulated if the starting point is not the separation of man and environment as in traditional cognitive psychology, but a unitary organism-environment system. According to the present formulation, mental activity is conceived as activity of the whole (...) class='Hi'>organism-environment system and connected to the general development of life as a specific form of an organism-environment system comprising neurons. The advent of consciousness is regarded as a result of co-operation of such organism-environment systems. Consciousness is based on co-operation for the achievement of common results, and shared by the co-operating individuals (general consciousness), although each individual also makes it concrete from the perspective of his/her own body in the act of participation in common results (personal consciousness). Language is the means of formation of the co-operative system in the achievement of common results, and it is suggested that the use of language is related more to the type of co-operative system and intended common results than to any symbolic representation of the world. It is claimed that on this basis it is possible to develop psychology which takes seriously the concepts of mental activity and consciousness in the description of human action, but does not reduce these concepts either to biological or social factors. The present formulation should be regarded more as a conceptual outline than as a full-blown theory. (shrink)

In a military-sponsored research project begun during the Second World War, inmates of the Stateville Penitentiary in Illinois were infected with malaria and treated with experimental drugs that sometimes had vicious side effects. They were made into reservoirs for the disease and they provided a food supply for the mosquito cultures. They acted as secretaries and technicians, recording data on one another, administering malarious mosquito bites and experimental drugs to one another, and helping decide who was admitted to the project (...) and who became eligible for early parole as a result of his participation. Thus, the prisoners were not simply research subjects; they were deeply constitutive of the research project. Because a prisoners time on the project was counted as part of his sentence, and because serving on the project could shorten ones sentence, the project must be seen as simultaneously serving the functions of research and punishment. Michel Foucault wrote about such mixed mechanisms in his Discipline and punish. His shining example of such a transparent and subtle style of punishment was the panopticon, Jeremy Benthams architectural invention of prison cellblocks arrayed around a central guard tower. Stateville prison was designed on Benthams model; Foucault featured it in his own discussion. This paper, then, explores the power relations in this highly idiosyncratic experimental system, in which the various roles of model organism, reagent, and technician are all occupied by sentient beings who move among them fluidly. This, I argue, created an environment in the Stateville hospital wing more panoptic than that in the cellblocks. Research and punishment were completely interpenetrating, and mutually reinforcing. (shrink)

Modern ethical perspectives toward the environment often emphasize the connection of humans to a broader biotic community. The full intimacy of this connectedness, however, is only now being revealed as scientific findings in developmental biology and genetics provide new insights into the importance of environmental interaction for the development of organisms. These insights are reshaping our understanding of how organism-environment interaction contributes to both consistency and variation in organism development, and leading to a new perspective whereby an “ (...) class='Hi'>organism” is not solely viewed as the adaptive product of evolutionary selection to an external environment over generations, but as continuously being constructed through systems of interactions that link an organism’s characteristics developmentally to the physical and social influences it experiences during life. This newfound emphasis on “interaction” leads to an interdependency whereby any change to an “environment” impacts the interacting “organism,” and an alteration to the “organism” eventually affects its “environment.” The causal reciprocity embedded within this organism-environment interdependency holds implications for our moral obligations to environments, given their compulsory role in shaping all organisms including ourselves. (shrink)

A number of philosophers maintain that the destruction of an embryo in the first 2 weeks after fertilization is not morally problematic as it is metaphysically impossible for any human organism to then have existed. We contend that the typical adult human organism was once a zygote so there is no metaphysical shortcut to justify early abortion. We show that five arguments against human organisms ever having been zygotes fail. All of the arguments have to (...) do with one variant or another of the zygote or early embryo dividing. They do not provide any reason to believe that since some adult organisms are not identical to zygotes due to earlier divisions, none could have been. (shrink)

In explicating his version of the Organism View, Eric Olson argues that you begin to exist only after twinning is no longer possible and that you cannot survive a process of inorganic replacement. Assuming the correctness of the Organism View, but pace Olson, I argue in this paper that the Organism View does not require that you believe either proposition. The claim I shall make about twinning helps to advance a debate that currently divides defenders of the (...) Organism View, while the claim I shall make about inorganic replacement will help to put the Organism View on a par with its rival views by allowing it to accommodate a plausible intuition that its rivals can accommodate, namely, the intuition that you can survive a process of inorganic replacement. Both claims, I shall also argue, are important for those who are interested in the identity condition of a human organism, even if they do not hold the view that you are essentially an organism. (shrink)

Model organisms became an indispensable part of experimental systems in molecular developmental and cell biology, constructed to investigate physiological and pathological processes. They are thought to play a crucial role for the elucidation of gene function, complementing the sequencing of the genomes of humans and other organisms. Accordingly, historians and philosophers paid considerable attention to various issues concerning this aspect of experimental biology. With respect to the representational features of model organisms, that is, their status as models, the main focus (...) was on generalization of phenomena investigated in such experimental systems. Model organisms have been said to be models for other organisms or a higher taxon. This, however, presupposes a representation of the phenomenon in question. I will argue that prior to generalization, model organisms allow researchers to built generative material models of phenomena – structures, processes or the mechanisms that explain them – through their integration in experimental set-ups that carve out the phenomena from the whole organism and thus represent them. I will use the history of zebrafish biology to show how model organism systems, from around 1970 on, were developed to construct material models of molecular mechanisms explaining developmental or physiological processes. (shrink)

Many debates about the moral status of things—for example, debates about the natural rights of human fetuses or nonhuman animals—eventually migrate towards a discussion of the capacities of the things in question—for example, their capacities to feel pain, think, or love. Yet the move towards capacities is often controversial: if a human’s capacities are the basis of its moral status, how could a human having lesser capacities than you and I have the same "serious" moral status as (...) you and I? This book answers this question by arguing that if something is human, it has a set of typical human capacities; that if something has a set of typical human capacities, it has serious moral status; and thus all human beings have the same sort of serious moral status as you and I. Beginning from what our common intuitions tell us about situations involving "temporary incapacitation"—where a human organism has, then loses, then regains a certain capacity—this book argues for substantive conclusions regarding human fetuses and embryos, humans in a permanent vegetative state, humans suffering from brain diseases, and humans born with genetic disorders. Since these conclusions must have some impact on our ongoing moral and political debates about the proper treatment of such humans, this book will be useful to professionals and students in philosophy, bioethics, law, medicine, and public policy. (shrink)

Recent theories in cognitive science have begun to focus on the active role of organisms in shaping their own environment, and the role of these environmental resources for cognition. Approaches such as situated, embedded, ecological, distributed and particularly extended cognition look beyond ‘what is inside your head’ to the old Gibsonian question of ‘what your head is inside of’ and with which it forms a wider whole—its internal and external cognitive niche. Since these views have been treated as a radical (...) departure from the received view of cognition, their proponents have looked for support to similar extended views within (the philosophy of) biology, most notably the theory of niche construction. This paper argues that there is an even closer and more fruitful parallel with developmental systems theory and developmental niche construction. These ask not ‘what is inside the genes you inherited’, but ‘what the inherited genes are inside of’ and with which they form a wider whole—their internal and external ontogenetic niche, understood as the set of epigenetic, social, ecological, epistemic and symbolic legacies inherited by the organism as necessary developmental resources. To the cognizing agent, the epistemic niche presents itself not just as a partially self-engineered selective niche, as the niche construction paradigm will have it, but even more so as a partially self-engineered ontogenetic niche, a problem-solving resource and scaffold for individual development and learning. This move should be beneficial for coming to grips with our own (including cognitive) nature: what is most distinctive about humans is their developmentally plastic brains immersed into a well-engineered, cumulatively constructed cognitive–developmental niche. (shrink)

This article proposes a cybernetic photographic theory that takes seriously the philosophical claim that cameras, images and human beings exist as evolving systems of machines-organisms. It provides an epistemological challenge to the modernist problematic of representation – namely, the emergence of human consciousness outside and above nature, and a rationalist distinction between an active, visual-reasoning subject and a passive object. I utilize the philosophy of Francois Lauruelle in order to foreground and deepen the understanding of the ethical thought (...) in cybernetics. My purpose is to build upon ethical philosophy that, as Gilbert Simondon contended, would ‘save the technical object’. There is some urgency to this task as, in saving machines from their own histories and statuses as non-human, representational things in the world, we may begin an ethico-political programme that evaluates the complementary creative processes of human and machine – in a word, our shared Art – in order to save ourselves. It is perhaps the case that any recuperation of cybernetic and photographic theory today be poised not to reckon with our ‘digital’ moment but rather with our Anthropocene era defined by human’s extinction level powers of destruction. (shrink)

This article proposes a cybernetic photographic theory that takes seriously the philosophical claim that cameras, images and human beings exist as evolving systems of machines-organisms. It provides an epistemological challenge to the modernist problematic of representation – namely, the emergence of human consciousness outside and above nature, and a rationalist distinction between an active, visual-reasoning subject and a passive object. I utilize the (non)philosophy of Francois Lauruelle in order to foreground and deepen the understanding of the ethical thought (...) in cybernetics. My purpose is to build upon ethical philosophy that, as Gilbert Simondon contended, would ‘save the technical object’. There is some urgency to this task as, in saving machines from their own histories and statuses as non-human, representational things in the world, we may begin an ethico-political programme that evaluates the complementary creative processes of human and machine – in a word, our shared Art – in order to save ourselves. It is perhaps the case that any recuperation of cybernetic and photographic theory today be poised not to reckon with our ‘digital’ moment but rather with our Anthropocene era defined by human’s extinction level powers of destruction. (shrink)

The goal of this paper is to explore, from a phenomenologically informed perspective, the phenomenon of the operative spatialization of human thinking, viewed in its relationship with the embodied human organism’s spatial experience. Operative spatialization in this context refers to the cognitive role and functioning of spatial schematizations and differentiations in human thinking. My particular focus is the domain of conceptualization. By drawing on Husserl’s discussion of the (linguistic) process of a sedimentation of meaning, I aim (...) to show that spatialization functions in a structurally ambivalent manner. On the one hand, spatialization predisposes and thus narrows the scope of human conceptual thought. On the other hand, spatialization establishes an implicit cognitive scaffold indispensable for the development and practice of human higher-order thinking. The structure and functioning of this scaffold, I argue, is intrinsically related to the spatial structure and dynamics of human embodiment. Synthesizing insights from phenomenological studies concerning the experiential constitution of space, and classic and recent research findings from fields such as cognitive linguistics and psychology concerning the cognitive dimension of image-schemas and gestural behavior, I argue that the living human body functions centrally as the sense-constitutive ‘site of conversion’ (Husserl) between concrete structures of spatial experience and abstract structures of conceptual thought. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 40.1 (2002) 122-123 [Access article in PDF] Book Review Spirits and Clocks: Machine & Organism in Descartes Dennis Des Chene. Spirits and Clocks: Machine & Organism in Descartes. Ithaca, NY and London: Cornell University Press, 2001. Pp. xiii + 181. Cloth, $39.95. Confronted with the thousandth "entirely new" interpretation of the Cartesian mind-body union, one sometimes wonders whether anything new can (...) in fact be said about the great Descartes. Once again, after his invaluable and prize-winning Physiologia (Cornell University Press, 1996), Des Chene proves that a serious historian, with a keen awareness of historical context, actually can. Unlike the usual accounts of Descartes's animal-machine, Des Chene does not concentrate on the all too familiar set of questions whether or not machines can think, sense, etc. Instead, Des Chene interprets the machine-metaphor the way Descartes meant it to be, viz. as a model for explaining animal and human physiology instead of (cognitive) psychology. Des Chene's central claim is that the Traité de l'Homme and Descartes's later (unpublished) physiological tracts are an attempt to replace scholastic commentaries on Aristotle's De Anima, itself discussed in this book's companion volume Life's Forms (Cornell University Press, 2000). Spirits and Clocks investigates how Descartes's general mechanistic program (outlined in Physiologia) is applied to the field of animal and human life. This project in itself had a far more lasting influence than Descartes's specific and often bizarre physiological explanations. Therefore, Des Chene rightly concentrates on the philosophical aspects of Descartes's general project of "mechanizing" physiology. His short but illuminating book studies a wide range of ontological, epistemological, and even aesthetic aspects of the machine metaphor and, although this is not the express goal [End Page 122] of the book, it also sheds new light on the epistemology and metaphysics of the Meditations. In this sense Spirits and Clocks is not only a significant contribution to the history of biology but first and foremost a must for historians of philosophy.Des Chene explains that the use of a machine model in physiology was neither new nor entirely unacceptable to the Aristotelians. What is new is Descartes's use of it. His mechanistic understanding of the body as a machine is incompatible with accepting the soul as the source of life and the principle of all our physiological and psychological capacities, while Aristotelians had no problem in accepting both the soul and certain machine models of the body. (Aristotle himself uses the lever to explain animal motion.) Des Chene sketches Descartes's attempt to explain all physiological processes by means of the physical properties of material parts that obey the general laws of motion, excluding all talk of ends. In this context, the use of illustrations is of considerable importance: though they cannot per se convey a denial of a "soul-model" of physiology, they strongly suggest that the (mechanistically understood) machine is all there is to say about the functions of human and animal bodies. Des Chene offers an interesting, albeit sometimes somewhat speculative and ahistoric, discussion of the aesthetic aspects of the machine model.As Des Chene showed in his Physiologia, the rejection of teleology is one of the main goals of Descartes's physics. However, although Descartes may be successful in rejecting the view that stones fall down from some kind of desire to reach their final destiny, he is less successful in denying that the eye is meant for seeing (and hence for our self-preservation). Des Chene gives a truly fascinating account of the limits of Descartes's denial of teleology in physiology. This includes questions about the physical unity of the human body: how can I explain why I have this body and how can I even identify this body as a unit without invoking ends? Similarly, Descartes takes the healthy, "normally" functioning body as the norm of his investigations. But, again, can he do so without acknowledging some form of teleology? Descartes's answer in most of these cases is that the final goals... (shrink)

Design is eminent throughout different disciplines of science, engineering, humanities, and art. However, within these disciplines, the way in which the term design is understood and applied differs significantly. There still is a profound lack of interdisciplinary research on this issue. The same term is not even guaranteed to carry the same meaning as soon as one crosses over to other disciplines. Therefore, related synergies between disciplines remain largely unexplored and unexploited.This book will address design in the hope of promoting (...) a deeper understanding of it across various disciplines, and to support Design Science as a discipline, which attempts to cover the vast number of currently isolated knowledge sources. (shrink)

Based on Kolchinsky and Wolpert’s work on the semantics of autonomous agents, I propose an application of Mathematical Logic and Probability to model cognitive processes. In this work, I will follow Bateson’s insights on the hierarchy of learning in complex organisms and formalize his idea of applying Russell’s Type Theory. Following Weaver’s three levels for the communication problem, I link the Kolchinsky–Wolpert model to Bateson’s insights, and I reach a semantic and conceptual hierarchy in living systems as an explicative model (...) of some adaptive constraints. Due to the generality of Kolchinsky and Wolpert’s hypotheses, I highlight some fundamental gaps between the results in current Artificial Intelligence and the semantic structures in human beings. In light of the consequences of my model, I conclude the paper by proposing a general definition of knowledge in probabilistic terms, overturning de Finetti’s Subjectivist Definition of Probability. (shrink)

John Dupré explores the ways in which we categorize animals, including humans, and comes to refreshingly radical conclusions. He opposes the idea that there is only one legitimate way of classifying things in the natural world, the 'scientific' way. The lesson we should learn from Darwin is to reject the idea that each organism has an essence that determines its necessary place in the unique hierarchy of things. Nature is not like that: it is not organized in a single (...) system. For instance, there is no universal principle by which organisms can be sorted into species. We are obliged to accept that different classificatory schemes are equally valid, and to take a pluralistic view of biology and the human sciences. These provocative and readable essays move on to discuss a set of contentious topics relating to human nature. To start with, Dupré argues that the concept of a universal human nature should be rejected. He questions the relevance of evolution to explanation of human behaviour, and casts doubt on the concept of normality in human behaviour. He shows that misunderstanding of biology and evolution has lead to widespread misconceptions about human sex and gender-in particular, about sexual behaviour and gender roles. The books concludes with a pair of essays about the differences between humans and animals, which may not be quite so clear-cut as we think. (shrink)

Plotinus, following certain Platonic cues, maintains that ‘we’ and ‘the true human being’ correspond to the rational part of the embodied human soul. This view is counterintuitive because it is natural to see ourselves and our humanity as including parts of the human organism additional to reason. In this paper, I propose that Plotinus’ view that we are our rational part is best understood as expressing a teleological claim. Since our proper end is an activity of (...) the rational part of soul, it is appropriate to identify our nature with that part of the organism alone. (shrink)

A text, primarily behavioristic in approach, covering the psychological and physiological development of the human organism. Its analyses of ontogenetic change are supplemented with brief phylogenetic descriptions.--A. R.

The idea of organism, which of recent years has bulked so largely in scientific, and especially in biological, theory has been developed mainly in reference to living organisms, and has been extended to cover such systems as human societies, crystals, molecules and atoms—and indeed the whole universe has been interpreted as an organism. This use of the term, however, includes different ways in which parts may be together in a system. The belief that the principle of (...) class='Hi'>organism has been wrongly extended to explain certain co-ordinations of vital processes which require a different type of explanation is the reason for this addition to the immense literature on the subject of organism. (shrink)

Human suicide presents a fundamental problem for the scientific analysis of behavior. This problem has been neither appreciated nor confronted by research and theory. Almost all other behavior exhibited by humans and nonhumans can be viewed as supporting the behaving organism's biological fitness and advancing the welfare of its genes. Yet suicide acts against these ends, and does so more directly and unequivocally than any other form of maladaptive behavior. Four heuristic models are presented here to account for (...) suicide in an evolutionary and sociobiological framework. The first model attributes suicide to the extraordinary development of learning and cultural evolution in the human species. Learning may make human behavior so independent of biological constraints that it can occasionally assume a form entirely contrary to the principles of biological evolution. The second model attributes suicide to a breakdown of adaptive mechanisms in extremely stressful novel environments. The third model involves kin and group selection, arguing that in limited circumstances suicide may occur because of beneficial effects it has on other, surviving individuals who share the suicidal individual's genes. The last model suggests that suicide should be tolerated by evolution when it has no effect on the gene pool. This model holds particular promise in accounting for aspects of suicide not attributable to culture. The evidence indicates that suicide is most common in individuals who are unlikely to reproduce and unable to engage in productive activity; such individuals are least capable of promoting their genes. A complete explanation of suicide may derive only from an analysis of its biological significance. (shrink)

According to neo-Aristotelian ethical naturalism, moral goodness is an instance of natural goodness, a kind of normativity supposedly already present in nature in the biological realm of non-human living things. Proponents of this view appeal to Michael Thompson’s conception of a life-form--the form of a living organism--to give an account of natural goodness. However, although neo-Aristotelians call themselves naturalists, they hardly ever consult the science of biology to defend their commitments regarding biological organisms. This has led many critics (...) to argue that the neo-Aristotelian account of natural normativity is out of touch with the findings of modern evolutionary biology. One line of response to this objection, presented by John Hacker-Wright and Micah Lott, claims that the neo-Aristotelian concept of a living organism has to be presupposed in evolutionary biology as long as organisms are the subjects of evolutionary explanation. In this paper, I examine this response by tracing the concept of organism in modern evolutionary biology. I first argue that the Modern Synthesis theory of evolution, which understands evolution as change in gene frequencies within a population, does not presuppose the relevant concept of organism. I then explore an alternative view of evolution that has emerged in the past twenty years from advances in evolutionary developmental biology. I argue that this so called ‘evo-devo’ approach makes room for an explanatory concept of organism that can be reconciled with the neo-Aristotelian view. Moreover, I argue that although the explanatory role of the concept of organism in evolutionary biology is still contentious, the well-established role of this concept in developmental biology can be used to defend the biological commitments of neo-Aristotelian naturalism. (shrink)

Research in evolutionary biology and philosophy of biology and cognition strongly suggests that human organisms modify their environment through active processes of niche construction. Recently, proponents of the free-energy principle and variational active inference have argued that their approach can deepen our understanding of the reciprocal causal relationship between organisms and their niche on various scales. This paper examines the feasibility and scope of variational formalisations and conceptualisations of the organism-niche nexus with a particular focus on the extended (...) active inference account. I will draw a conceptual distinction between selective niche construction, developmental niche construction, and organism-niche coordination dynamics and argue that these notions capture different causal patterns, each of which with a distinct scope. Against this background, I will analyse and discuss the extended active inference account and its strategy to integrate variational active inference with work on extended cognition. The proponents of extended active inference assume that their account can provide an explanation of selective niche construction, developmental niche construction, and organism-niche coordination dynamics. However, my key claim will be that this account has the potential to elucidate the workings of organism-niche coordination dynamics, but does not adequately capture the causal patterns of selective niche construction and developmental niche construction. (shrink)

Figurativity has attracted scholars' attention for thousands of years and yet there are still open questions concerning its nature. Figurativity and Human Ecology endorses a view of figurativity as ubiquitous in human reasoning and language, and as a key example of how a human organism and its perceived or imagined environment co-function as a system. The volume sees figurativity not only as embedded in an environment but also as a way of acting within that environment. It (...) places figurativity within an ecological context, and approaches it as a phenomenon which cuts across bodily, psychological, linguistic, social, cultural and natural environments. Figurativity and Human Ecology will appeal to those interested in the analysis of the all-encompassing creativity of the human mind and in the methodological difficulties associated with the study of cognition. (shrink)

Human enhancement has emerged in recent years as a blossoming topic in applied ethics. With continuing advances in science and technology, people are beginning to realize that some of the basic parameters of the human condition might be changed in the future. One important way in which the human condition could be changed is through the enhancement of basic human capacities. If this becomes feasible within the lifespan of many people alive today, then it is important (...) now to consider the normative questions raised by such prospects. The answers to these questions might not only help us be better prepared when technology catches up with imagination, but they may be relevant to many decisions we make today, such as decisions about how much funding to give to various kinds of research. Enhancement is typically contraposed to therapy. In broad terms, therapy aims to fix something that has gone wrong, by curing specific diseases or injuries, while enhancement interventions aim to improve the state of an organism beyond its normal healthy state. However, the distinction between therapy and enhancement is problematic, for several reasons. First, we may note that the therapy-enhancement dichotomy does not map onto any corresponding dichotomy between standard-contemporary-medicine and medicineas-it-could-be-practised-in-the-future. Standard contemporary medicine includes many practices that do not aim to cure diseases or injuries. It includes, for example, preventive medicine, palliative care, obstetrics, sports medicine, plastic surgery, contraceptive devices, fertility treatments, cosmetic dental procedures, and much else. At the same time, many enhancement interventions occur outside of the medical framework. Office workers enhance their performance by drinking coffee. Make-up and grooming are used to enhance appearance. Exercise, meditation, fish oil, and St John’s Wort are used to enhance mood. Second, it is unclear how to classify interventions that reduce the probability of disease and death.. (shrink)

Humans often behave altruistically towards strangers with no chance of reciprocation. From an evolutionary perspective, this is puzzling. The evolution of altruistic cooperative behavior—in which an organism’s action reduces its fitness and increases the fitness of another organism —only makes sense when it is directed at genetically related organisms or when one can expect the favor to be returned. Therefore, evolutionary theorists such as Sober and Wilson have argued that we should revise Neo-Darwininian evolutionary theory. They argue that (...) human altruism evolved through group selection in which groups of altruists were naturally selected because they had a comparative advantage over other groups. Wilson and Sober’s hypothesis attracted followers but is rejected by most of their peers. The heated debate between advocates and critics of group selection often suffers from a lack of conceptual clarity. In response, I set out to clearly distinguish ‘genetic’ from ‘cultural’ group selection and argue that the latter does not face the potentially debilitating problems plaguing the former. I defend the claim that human altruistic dispositions evolved through cultural group selection and gene-culture coevolution and offer empirical evidence in support. I also argue that actual altruistic behavior often goes beyond the kind of behavior humans have evolved to display. Conscious and voluntary reasoning processes, I show, have an important role in altruistic behavior. This is often overlooked in the scientific literature on human altruism. (shrink)

In order to explain the behavior of a human organism, it is necessary to take its environment into consideration. Except for very severe psychotic withdrawal, this has been recognized as a near triviality since Aristotle. But although consideration of the environment may be necessary, it is not sufficient, and it is now generally conceded that a man's behavior cannot be explained solely from a consideration of his present environment and a history of his responses to past environments.

Plato argued that knowledge of human nature can be reached through dialogue and dialectical method in accordance with the Socratic heritage. In his philosophy, man can be defined as being capable of rationally answering a rational question. By giving rational answers to himself and others, human also becomes a moral subject. In Plato's philosophy, we see a clear program based on human nature. Issues related to human nature are discussed in the process of applying Plato's theory (...) of ideas to the field of morality, art, politics and education. What emerges in practice, for example, right and fair behavior is a manifestation of the principle of truth and justice. According to Plato, man reflects the character of the state he lives in. To understand a person, it is necessary to consider the society in which he lives. The state is not an institution that people come together and establish with their own will, but an organism, a whole. According to Plato, in order to grasp the true meaning of human society and to arrange it properly, one must first comprehend the astronomical cosmos. Because, knowing the meaning of the concepts of harmony and order is possible only by understanding the astronomical cosmos, which is the expression of an eternal order. While studying the astronomical cosmos, a man comes to the idea of harmony and order itself. Indeed, the infinite canonical and harmonious movements of the stars in this pre-eternal order on their perennials lead to the concept of law itself. People who admire this harmony and order in the sky want to realize a model of it on earth. He concludes that the laws that will rule over the human world must be continuous and compatible, just like the laws in the world of stars. Thus, the state must be an earthly model of the astronomical cosmos. If a person lives in the state, he should realize this harmony and order in the state in his own spirit. (shrink)