This article describes the development, implementation, and evaluation of a complex methotrexate ethics case used in teaching a Pharmacy Law and Ethics course. Qualitative analysis of student reflective writings provided useful insight into the students’ experience and comfort level with the final ethics case in the course. These data demonstrate a greater student appreciation of different perspectives, the potential for conflict in communicating about such cases, and the importance of patient autonomy. Faculty lessons learned are also described, facilitating adoption of (...) this methotrexate ethics case by other healthcare profession educators. (shrink)

Background: Brain-dead humans retain many of the physiologic functions of living humans, but they are legally dead and cannot be physically harmed by participation in research. Stakeholder opinions...

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...) of an effective comparison and integration across domains, and for assessing whether or not to use functional diversity approaches for developing ecological management strategies. The objective of this contribution is to identify and critically analyze the most salient of these assumptions. To this aim, we provide an “epistemic roadmap” that pinpoints these assumptions along a set of historical, conceptual, empirical, theoretical, and normative dimensions. (shrink)

We consider three accepted truths about iris biometrics, involving pupil dilation, contact lenses and template aging. We also consider a relatively ignored issue that may arise in system interoperability. Experimental results from our laboratory demonstrate that the three accepted truths are not entirely true, and also that interoperability can involve subtle performance degradation. All four of these problems affect primarily the stability of the match, or authentic, distribution of template comparison scores rather than the non-match, or imposter, distribution of scores. (...) In this sense, these results confirm the security of iris biometrics in an identity verification scenario. We consider how these problems affect the usability and security of iris biometrics in large-scale applications, and suggest possible remedies. (shrink)

Resumo Neste artigo, defender-se-á uma interpretação do filme A Time to Kill, como sendo uma narrativa cinematográfica falível, mesmo sem a presença de um narrador. Neste texto, assume-se, que uma narrativa falível resulta de um defeito estético e ético do filme. Deste modo, a estrutura estética do filme representa a intenção do realizador em contar a sua versão da história, influenciando assim o seu significado e efeito empático. Com o evoluir da narrativa cinematográfica, as regras de inferência tornam-se cada vez (...) mais complexas. Ainda assim, a convenção cinematográfica estabelece um contexto e define limites identificadores para a sua interpretação. Uma história mal contada inibe a reconstrução imaginativa do espectador, no que diz respeito às motivações das personagens e da causalidade narrativa. Portanto, a qualidade narrativa é essencial para o raciocínio narrativo e empatia estética. Se a narrativa oferece uma compreensão do mundo e de outras pessoas, que de outra forma seriam inacessíveis, e se a forma ou o estilo da narrativa determinam a sua eficácia, então, as formas assumidas pelas nossas histórias têm consequências epistemológicas. Palavras-chave : estética, ética, identificação, narrativa falível, narrativa, raçaIn this paper, I argue for an interpretation of A Time to Kill as an unreliable, yet narrator-less, cinematic narrative. In my view, unreliable narration is an aesthetic and ethical flaw of the film rather than of the narrator. Thus, the film’s aesthetic structure represents the director’s storytelling intentions, and influences its meaning and empathic affect. As cinematic narrative evolves, rules of inference become increasingly complex. Still, filmic convention establishes a context and sets identifiable boundaries for interpretation. A poorly told story inhibits the viewer’s imaginative reconstruction of narrative causation and characters’ motives. Thus, narrative quality is essential to narrative reasoning and aesthetic empathy. If narrative provides an understanding of the world and other people that is otherwise inaccessible, and if the form or style of narrative determines its effectiveness, then the forms our stories take have epistemological consequences. Keywords : aesthetics, ethics, identification, narrative, race, unreliable narrative. (shrink)

Introduction: If ever attained, adopting native-like accent is achieved late in the learning process. Resemblance between L2 and mother tongue can facilitate L2 learning. In particular, cognates (phonologically and semantically similar words across languages), offer the opportunity to examine the issue of foreign accent in quite a unique manner. Methods: Twelve Spanish speaking (L1) adults learnt French (L2) cognates and practiced their native-like pronunciation by means of a computerized method. After consolidation, they were tested on L1 and L2 oral picture- (...) naming during fMRI scanning. Results and Discussion: The results of the present study show that there is a specific impact of accent on brain activation, even if L2 words are cognates, and belong to a pair of closely related languages. Results point that the insula is a key component of accent processing, which is in line with reports from patients with foreign accent syndrome (FSA) following damage to the insula (e.g. Moreno-Torres et al., 2013; Katz et al., 2012; Tomasino et al., 2013), and healthy L2 learners (Chee et al., 2003). Thus, the left insula has been consistently related to the integration of attentional and working memory abilities, together with fine-tuning of motor programming to achieve optimal articulation. (shrink)

Adults’ intentionality judgments regarding an action are influenced by their moral evaluation of this action. This is clearly indicated in the so-called side-effect effect: when told about an action (e.g. implementing a business plan) with an intended primary effect (e.g. raise profits) and a foreseen side effect (e.g. harming/helping the environment), subjects tend to interpret the bringing about of the side effect more often as intentional when it is negative (harming the environment) than when it is positive (helping the environment). (...) From a cognitive point of view, it is unclear whether the side-effect effect is driven by the moral status of the side effects specifically, or rather more generally by its normative status. And from a developmental point of view, little is known about the ontogenetic origins of the effect. The present study therefore explored the cognitive foundations and the ontogenetic origins of the side-effect effect by testing 4-to 5-year-old children with scenarios in which a side effect was in accordance with/violated a norm. Crucially, the status of the norm was varied to be conventional or moral. Children rated the bringing about of side-effects as more intentional when it broke a norm than when it accorded with a norm irrespective of the type of norm. The side-effect effect is thus an early-developing, more general and pervasive phenomenon, not restricted to morally relevant side effects. (shrink)

In The Ethics of Food, Gregory E. Pence brings together a collection of voices who share the view that the ethics of genetically modified food is among the most pressing societal questions of our time. This comprehensive collection addresses a broad range of subjects, including the meaning of food, moral analyses of vegetarianism and starvation, the safety and environmental risks of genetically modified food, issues of global food politics and the food industry, and the relationships among food, evolution, and human (...) history. (shrink)

This is an extended essay review of Tanya and Jeffrey Bub’s Totally Random: Why Nobody Understands Quantum Mechanics: A serious comic on entanglement. We review the philosophical aspects of the book, provide suggestions for instructors on how to use the book in a class setting, and evaluate the authors’ artistic choices in the context of comics theory. Although Totally Random does not defend any particular interpretation of quantum mechanics, we find that, in its mode of presentation, Totally Random is (...) a beautiful expression and illustration of the information-theoretic interpretation and its value. (shrink)

ḥeleḳ 1. Peraḳim 1-34 -- ḥeleḳ 2. Peraḳim 35-53.

Peraḳim 1-12 - ḥeleḳ 2 be-sefer ha-tanya, be-tosefet beʼurim u-marʼe meḳomot, mahadurah 2 ʻim hosafot ṿe-tiḳunim.

ḥeleḳ 1. Be-Sefer ha-Zohar ha-ḳadosh ṿe-Tiḳune ha-Zohar, hashmaṭot ha-Zohar, Zohar ḥadash, Sefer ha-Bahir --.

This is the first version of the Rabbi Schneur Zalman's magnum opus -- Tanya, before it was finalized by him and published. This verison was published on behest of the Lubavitcher Rebbe in 1981. An important scholarly edition which shines a spotlight on the process used by the Alter Rebbe in publishing what has become known as the "written law of Chasidism.".

Bernard E. Harcourt, Illusion of Order: The False Promise of Broken Windows Policing Cambridge, MA: Harvard University Press, 2001, x + 294 pp. David Garland, The Culture of Control: Crime and Social Order in Contemporary Society Chicago: University of Chicago Press, 2001, xiii + 307 pp. Andrea McArdle and Tanya Erzen (eds.), Zero Tolerance: Quality of Life and the New Police Brutality in New York City New York: New York University Press, 2001, xvi + 299 pp. Phillipe Bourgois, In (...) Search of Respect: Selling Crack in El Barrio New York: Cambridge University Press, 1995, xii + 392 pp. Loïc Wacquant, Les Prisons de la Misère Paris: Raisons D'Agir Éditions, 1999, 189 pp. (shrink)

This collection reconsiders the notion of life and conceptualizes those forms of life which have been excluded from modern philosophy, such as post-Anthropocene life, the life of non-human animals and the life of inorganic objects"-- Provided by publisher.

The risk and crisis communication process in public health emergencies (PHERCC, public health emergency risk and crisis communication) matrix, as proposed by Spitale, Germani, and Biller-Andorno (2...

La perspectiva evolutiva de Michael Ruse sobre la moral se caracteriza por combinar dos aspectos aparentemente contradictorios: por un lado, un escepticismo metaético y, por otro lado, una defensa de la ética normativa. Siguiendo la distinción de Daniel Dennett entre explicaciones con ‘ganchos celestiales’, que apelan a entidades sobrenaturales, y con ‘grúas’, que se adecúan a la teoría de la evolución por selección natural, la propuesta de Ruse busca llevar la comprensión de la ética y de la metaética en clave (...) de ‘grúa’ hasta sus últimas consecuencias. Ahora bien, la propuesta ruseana parece llegar a una aporía. Esto porque si bien en su propuesta se plantea una defensa de la ética normativa, Ruse le adjudica un rol destacado a las ‘disposiciones mentales innatas’ (vinculadas con piezas de psicología como las intuiciones o emociones morales), quedando todavía, aparentemente, un cabo suelto de su filosofía: cómo capturar, sin diluir, o sin reducir al mínimo, la normatividad de dicha ética (que el autor llama a veces ‘sustantiva’ en contraste con la metaética). En este artículo nos proponemos conservar la comprensión de la moral en clave de ‘grúa’ propuesta por Ruse pero, al mismo tiempo, recuperar una noción de razonamiento moral con mayor injerencia en la normatividad ética. Para ello, recurriremos al concepto de ‘metacognición’ que, una vez definido, nos permitirá poner en evidencia de qué manera el conocimiento de los procesos y productos cognitivos propios puede jugar un papel en el razonamiento moral destinado a inhibir disposiciones tendencialmente egoístas. (shrink)

ABSTRACT In this commentary, I delve into areas in which I agree as well as disagree with Glen Pettigrove’s interesting ideas. I am very much in agreement with his views about the limited use of the proportionality principle in attempting to explain what virtue adds to value. The main portion of his essay, however, lies in his treatment of three approaches purporting to explain how virtue adds to value: Hurka’s recursive theory; what Pettigrove calls the ‘response-dependent’ view; and his own (...) account, which he calls the ‘modus operandi’ view. Though I agree with his criticisms of the recursive theory, I express concerns about his treatment of the response-dependent view, as well as about Pettigrove’s own modus operandi account. (shrink)

Each time we take a turn in conversation we indicate what we know and what we think others know. However, knowledge is neither static nor absolute. It is shaped by those we interact with and governed by social norms - we monitor one another for whether we are fulfilling our rights and responsibilities with respect to knowledge, and for who has relatively more rights to assert knowledge over some state of affairs. This book brings together an international team of leading (...) linguists, sociologists and anthropologists working across a range of European and Asian languages to document some of the ways in which speakers manage the moral domain of knowledge in conversation. The volume demonstrates that if we are to understand how speakers manage issues of agreement, affiliation and alignment - something clearly at the heart of human sociality - we must understand the social norms surrounding epistemic access, primacy and responsibilities. (shrink)

I. Introduction Two kinds of remedies have traditionally been employed for breach of contract: legal relief and equitable relief. Legal relief normally takes the form of money damages. Equitable relief normally consists either of specific performance or an injunction – that is, the party in breach may be ordered to perform an act or to refrain from performing an act. In this article I will use a “consent theory of contract” to assess the choice between money damages and specific performance. (...) According to such a theory, contractual obligation is dependent on more fundamental entitlements of the parties and arises as a result of the parties' consent to transfer alienable rights. My thesis will be that the normal rule favoring money damages should be replaced with one that presumptively favors specific performance unless the parties have consented to money damages instead. The principal obstacle to such an approach is the reluctance of courts to specifically enforce contracts for personal services. The philosophical distinction between alienable and inalienable rights bolsters this historical reticence, since a right to personal services may be seen as inalienable. I will then explain why, if the subject matter of a contract for personal services is properly confined to an alienable right to money damages for failure to perform, specific enforcement of such contracts is no longer problematic. Finally, I shall consider whether the subject matter of contracts for corporate services is properly confined to money damages like contracts for personal services, or whether performance of corporate services can be made the subject of a valid rights transfer and judicially compelled in the same manner as contracts for external resources. (shrink)

This study compares 20 subjects, in each of three different settings, with serious psychotic disorder who hear voices, and compares their voice-hearing experience. We find that while there is much that is similar, there are notable differences in the kinds of voices that people seem to experience. In a California sample, people were more likely to describe their voices as intrusive unreal thoughts; in the South Indian sample, they were more likely to describe them as providing useful guidance; and in (...) our West African sample, they were more likely to describe them as morally good and causally powerful. What we think we may be observing is that people who fall ill with serious psychotic disorder pay selective attention to a constant stream of many different auditory and quasi-auditory events because of different “cultural invitations”—variations in ways of thinking about minds, persons, spirits and so forth. Such a process is consistent with processes described in the cognitive psychology and psychiatric anthropology literature, but not yet described or understood with respect to cultural variations in auditory hallucinations. We call this process “social kindling.”. (shrink)

Philosophers have debated for millennia about whether moral requirements are always rational to follow. The background for these debates is often what I shall call “the self-interest model.” The guiding assumption here is that the basic demand of reason, to each person, is that one must, above all, advance one's self-interest. Alternatively, debate may be framed by a related, but significantly different, assumption: the idea that the basic rational requirement is to develop and pursue a set of personal ends in (...) an informed, efficient, and coherent way, whether one's choice of ends is based on self-interested desires or not. For brevity I refer to this as “the coherence-and-efficiency model.” Advocates of both models tend to think that, while it is sufficiently clear in principle what the rational thing to do is, what remains in doubt is whether it is always rational to be moral. They typically assume that morality is concerned, entirely or primarily, with our relations to others, especially with obligations that appear to require some sacrifice or compromise with the pursuit of self-interest. (shrink)

Este ensaio estabelece uma comparação estética e fenomenológica entre os pensamentos de Yves-Klein e Merleau-Ponty. Se o pintor materializou as suas reflexões e concepções em obra pictórica, o fenomenólogo francês dissertou na escrita filosófica o resultado da sua reflexão. Da análise conjunta entre um e outro resulta esta fenomenologia e estética comparativa que apresenta alguns conceitos fundamentais que alimentaram essas reflexões, tais como a visibilidade, o corpo, o mundo. Assim, para além dessa comparação, este ensaio viabiliza o diálogo entre ambos.Palavras-chave: (...) Corpo. Mundo. Visibilidade. Merleau-Ponty. Yves Klein Abstract:This essay establishes an aesthetic and phenomenological comparison between the thoughts of Yves-Klein and Merleau-Ponty. If the painter materialized his reflections and concepts in pictorial work, the French phenomenologist disserted in the philosophical writing the result of his reflection. From the joint analysis between one and the other, this phenomenology and comparative aesthetics results, which presents some fundamental concepts that fed these reflections such as visibility, the body, the world. Thus, in addition to this comparison, this essay enables the dialogue between both.Keywords: Body. World. Visibility. Merleau-Ponty. Yves Klein. (shrink)

The creative process has the potential to increase wellbeing and foster human flourishing (Dolan and Metcalfe, 2012 ; Forgeard and Eichner, 2014 ; O’Brien and Murray, 2015 ; Conner et al., 2018 ; Kaufman, 2018 ), yet has received little attention in the humanistic management literature. In this paper, we present three experiments showing that idea originators experience greater relationship conflict with counterparts who have committed perceived “idea theft”, i.e., proposed identical or related ideas. We test a model that identifies (...) a mechanism—self-threat—that mediates the relationship between idea theft and relationship conflict and identifies an intervention to ameliorate that self-threat via self-affirmation. Study 1 demonstrates the idea originator’s attribution of malign attributions to, and negative moral emotions toward, the counterpart. Study 2 demonstrates that idea originators ostracize both those who propose identical ideas and those who propose merely related ideas. In Study 3, evidence for self-threat as the mechanism underlying the negative relational consequences is provided via both a direct test of mediation as well as via moderation by self-affirmation. Our research contributes to the nascent idea theft literature and suggests a way to reduce its negative consequences. (shrink)

Alfred Edward Housman (1859–1936), ki je kasneje postal angleški pesnik in eden največjih filologov svojega časa, je svoj zafrkantski »fragment« objavil pri triindvajsetih, leta 1883, v reviji Bromsgrovian. Revijo je izdajala Bromsgrove School, kjer se je šolal kot najstnik (1870–77); na šolo, ki je prva prepoznala njegov jezikovni in pesniški talent, se je za kratek čas (1881–82) vrnil kot pomožni učitelj po ne­pričakovanem študijskem porazu na Oxfordu. Kot ugotavlja Ralph Marcellino, ni naključje, da besedilo paro­dira predvsem Ajshila, ki je bil (...) Housmanov najljubši pesnik. V njem odzvanja Oresteja, zlasti drami Agamemnon in Prinašalke pitnih darov, verjetno zato, ker so ju dijaki na šoli, kjer je poučeval, pri pouku največ brali. Prav ta ciljna publika je znala ceniti norčevanje iz retoričnih figur ter sintaktičnih konstrukcij, ki jim jih je njihov pomožni učitelj vbijal v glavo. (shrink)