This article describes the development, implementation, and evaluation of a complex methotrexate ethics case used in teaching a Pharmacy Law and Ethics course. Qualitative analysis of student reflective writings provided useful insight into the students’ experience and comfort level with the final ethics case in the course. These data demonstrate a greater student appreciation of different perspectives, the potential for conflict in communicating about such cases, and the importance of patient autonomy. Faculty lessons learned are also described, facilitating adoption of (...) this methotrexate ethics case by other healthcare profession educators. (shrink)

Background: Brain-dead humans retain many of the physiologic functions of living humans, but they are legally dead and cannot be physically harmed by participation in research. Stakeholder opinions...

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...) of an effective comparison and integration across domains, and for assessing whether or not to use functional diversity approaches for developing ecological management strategies. The objective of this contribution is to identify and critically analyze the most salient of these assumptions. To this aim, we provide an “epistemic roadmap” that pinpoints these assumptions along a set of historical, conceptual, empirical, theoretical, and normative dimensions. (shrink)

Resumo Neste artigo, defender-se-á uma interpretação do filme A Time to Kill, como sendo uma narrativa cinematográfica falível, mesmo sem a presença de um narrador. Neste texto, assume-se, que uma narrativa falível resulta de um defeito estético e ético do filme. Deste modo, a estrutura estética do filme representa a intenção do realizador em contar a sua versão da história, influenciando assim o seu significado e efeito empático. Com o evoluir da narrativa cinematográfica, as regras de inferência tornam-se cada vez (...) mais complexas. Ainda assim, a convenção cinematográfica estabelece um contexto e define limites identificadores para a sua interpretação. Uma história mal contada inibe a reconstrução imaginativa do espectador, no que diz respeito às motivações das personagens e da causalidade narrativa. Portanto, a qualidade narrativa é essencial para o raciocínio narrativo e empatia estética. Se a narrativa oferece uma compreensão do mundo e de outras pessoas, que de outra forma seriam inacessíveis, e se a forma ou o estilo da narrativa determinam a sua eficácia, então, as formas assumidas pelas nossas histórias têm consequências epistemológicas. Palavras-chave : estética, ética, identificação, narrativa falível, narrativa, raçaIn this paper, I argue for an interpretation of A Time to Kill as an unreliable, yet narrator-less, cinematic narrative. In my view, unreliable narration is an aesthetic and ethical flaw of the film rather than of the narrator. Thus, the film’s aesthetic structure represents the director’s storytelling intentions, and influences its meaning and empathic affect. As cinematic narrative evolves, rules of inference become increasingly complex. Still, filmic convention establishes a context and sets identifiable boundaries for interpretation. A poorly told story inhibits the viewer’s imaginative reconstruction of narrative causation and characters’ motives. Thus, narrative quality is essential to narrative reasoning and aesthetic empathy. If narrative provides an understanding of the world and other people that is otherwise inaccessible, and if the form or style of narrative determines its effectiveness, then the forms our stories take have epistemological consequences. Keywords : aesthetics, ethics, identification, narrative, race, unreliable narrative. (shrink)

We consider three accepted truths about iris biometrics, involving pupil dilation, contact lenses and template aging. We also consider a relatively ignored issue that may arise in system interoperability. Experimental results from our laboratory demonstrate that the three accepted truths are not entirely true, and also that interoperability can involve subtle performance degradation. All four of these problems affect primarily the stability of the match, or authentic, distribution of template comparison scores rather than the non-match, or imposter, distribution of scores. (...) In this sense, these results confirm the security of iris biometrics in an identity verification scenario. We consider how these problems affect the usability and security of iris biometrics in large-scale applications, and suggest possible remedies. (shrink)

Adults’ intentionality judgments regarding an action are influenced by their moral evaluation of this action. This is clearly indicated in the so-called side-effect effect: when told about an action (e.g. implementing a business plan) with an intended primary effect (e.g. raise profits) and a foreseen side effect (e.g. harming/helping the environment), subjects tend to interpret the bringing about of the side effect more often as intentional when it is negative (harming the environment) than when it is positive (helping the environment). (...) From a cognitive point of view, it is unclear whether the side-effect effect is driven by the moral status of the side effects specifically, or rather more generally by its normative status. And from a developmental point of view, little is known about the ontogenetic origins of the effect. The present study therefore explored the cognitive foundations and the ontogenetic origins of the side-effect effect by testing 4-to 5-year-old children with scenarios in which a side effect was in accordance with/violated a norm. Crucially, the status of the norm was varied to be conventional or moral. Children rated the bringing about of side-effects as more intentional when it broke a norm than when it accorded with a norm irrespective of the type of norm. The side-effect effect is thus an early-developing, more general and pervasive phenomenon, not restricted to morally relevant side effects. (shrink)

Introduction: If ever attained, adopting native-like accent is achieved late in the learning process. Resemblance between L2 and mother tongue can facilitate L2 learning. In particular, cognates (phonologically and semantically similar words across languages), offer the opportunity to examine the issue of foreign accent in quite a unique manner. Methods: Twelve Spanish speaking (L1) adults learnt French (L2) cognates and practiced their native-like pronunciation by means of a computerized method. After consolidation, they were tested on L1 and L2 oral picture- (...) naming during fMRI scanning. Results and Discussion: The results of the present study show that there is a specific impact of accent on brain activation, even if L2 words are cognates, and belong to a pair of closely related languages. Results point that the insula is a key component of accent processing, which is in line with reports from patients with foreign accent syndrome (FSA) following damage to the insula (e.g. Moreno-Torres et al., 2013; Katz et al., 2012; Tomasino et al., 2013), and healthy L2 learners (Chee et al., 2003). Thus, the left insula has been consistently related to the integration of attentional and working memory abilities, together with fine-tuning of motor programming to achieve optimal articulation. (shrink)

In The Ethics of Food, Gregory E. Pence brings together a collection of voices who share the view that the ethics of genetically modified food is among the most pressing societal questions of our time. This comprehensive collection addresses a broad range of subjects, including the meaning of food, moral analyses of vegetarianism and starvation, the safety and environmental risks of genetically modified food, issues of global food politics and the food industry, and the relationships among food, evolution, and human (...) history. (shrink)

This is an extended essay review of Tanya and Jeffrey Bub’s Totally Random: Why Nobody Understands Quantum Mechanics: A serious comic on entanglement. We review the philosophical aspects of the book, provide suggestions for instructors on how to use the book in a class setting, and evaluate the authors’ artistic choices in the context of comics theory. Although Totally Random does not defend any particular interpretation of quantum mechanics, we find that, in its mode of presentation, Totally Random is (...) a beautiful expression and illustration of the information-theoretic interpretation and its value. (shrink)

ḥeleḳ 1. Peraḳim 1-34 -- ḥeleḳ 2. Peraḳim 35-53.

Peraḳim 1-12 - ḥeleḳ 2 be-sefer ha-tanya, be-tosefet beʼurim u-marʼe meḳomot, mahadurah 2 ʻim hosafot ṿe-tiḳunim.

ḥeleḳ 1. Be-Sefer ha-Zohar ha-ḳadosh ṿe-Tiḳune ha-Zohar, hashmaṭot ha-Zohar, Zohar ḥadash, Sefer ha-Bahir --.

This is the first version of the Rabbi Schneur Zalman's magnum opus -- Tanya, before it was finalized by him and published. This verison was published on behest of the Lubavitcher Rebbe in 1981. An important scholarly edition which shines a spotlight on the process used by the Alter Rebbe in publishing what has become known as the "written law of Chasidism.".

Bernard E. Harcourt, Illusion of Order: The False Promise of Broken Windows Policing Cambridge, MA: Harvard University Press, 2001, x + 294 pp. David Garland, The Culture of Control: Crime and Social Order in Contemporary Society Chicago: University of Chicago Press, 2001, xiii + 307 pp. Andrea McArdle and Tanya Erzen (eds.), Zero Tolerance: Quality of Life and the New Police Brutality in New York City New York: New York University Press, 2001, xvi + 299 pp. Phillipe Bourgois, In (...) Search of Respect: Selling Crack in El Barrio New York: Cambridge University Press, 1995, xii + 392 pp. Loïc Wacquant, Les Prisons de la Misère Paris: Raisons D'Agir Éditions, 1999, 189 pp. (shrink)

Growing concern has been expressed that we have entered a “post-truth” era in which each of us willfully believes whatever we choose, aided and abetted by alternative and social media that spin alternative realities for boutique consumption. A prime example of the belief in alternative realities is said to be acceptance of “conspiracy theories”—a term that is often used as a pejorative to indict claims of conspiracy that are so obviously absurd that only the unhinged could believe them. The epistemological (...) standard often involved in this indictment, however—the standard of “obvious” falsity—invites subjectivity in its application, because what is obviously false to one person can be common sense to another. This is not just a truism; considerable research suggests that people’s political beliefs, in general, and their acceptance or rejection of conspiracy theories in particular, tends in large part to be determined by partisan, ideological, and other priors. (shrink)

Victoria’s Voluntary Assisted Dying Act 2017 (Vic) became the first state law to permit VAD in Australia under limited circumstances from June 2019. Before this, many palliative care physicians relied on the doctrine of double effect (DDE) to justify the use of pain relievers for terminally ill patients that were known to hasten death. The DDE claims that there is a morally significant difference between intending evil and merely foreseeing some bad side-effect will occur as a result of one’s actions. (...) This article argues that the legacy of the DDE is promoting inequitable access to VAD in Victoria due to the assumption that death represents an “evil” for the patient and that the intentions of physicians providing VAD cannot be trusted. The latter claim relies on two common objections to the DDE: the risk of “purifying the intentions” and the issue of “closeness” when evaluating moral acts under this theory. (shrink)

Technology has advanced significantly over the past decades. Significant changes have occurred in the field of translation with the development of programs such as Google.translate and Yandex.translator. The presented applications are already being actively implemented in translation agencies to optimize translation activities, where written translations of documents, articles, annotations, etc. must be provided to customers as quick as possible. While working with popular science text, online programs help translators gain time, but this requires to edit the text. The artistic style (...) requires more concentration and dedication, because. the means of expression presented in it require taking into account the context and nuances of the use of certain units of language. Machine translation has the potential to become an indispensable assistant in the hands of a translator. This article discusses machine translation of expressive means, namely metaphors. The study is illustrated with examples and a comparative analysis of the translation of metaphorical units is carried out, the classification of metaphors is identified and an analysis is carried out with which means of expression the translator is able to cope with. The difficulties of translating metaphors are analyzed. (shrink)

L'incommensurable fait apparaître qu'il est des fêlures irréductibles dans notre expérience révélant de l'infini du sein même de cette expérience: entre le plaisir et la jouissance ou bien le rapport social et l'intime. L'inouï dit, non pas l'extraordinaire ou l'insolite, mais ce qui peut être au contraire le plus commun de notre expérience--mais que nous n'entendons pas parce que nous ne savons pas déborder les cadres figés de cette expérience. La vraie vie fait signe vers ce que, tout en étant (...) en vie, nous risquons de n'être toujours que dans une apparence de vie, ou pseudo-vie, sans accéder à vraiment vivre. Trois concepts proposés par François Jullien pour ne pas laisser rabattre notre vie, mais la porter à son déploiement. Contre les facilités du prêche et du marché du Bonheur, il faut penser ces concepts comme outils pour 'changer la vie.'"--Page 4 of cover. (shrink)

One of Edmund Husserl's theoretical priorities throughout his philosophical career was to understand the nature of perceptual experience. His analyses of perceptual experience had a profound impact on subsequent thinkers in the phenomenological tradition, such as Aron Gurwitsch and Maurice Merleau-Ponty. Naturally, his account of perception remains a topic of discussion among Husserl scholars. Despite the attention it has received over many decades, Husserl interpreters diverge considerably in how they understand his views and their relation to current debates in the (...) philosophy of perception. A case in point is Husserl's view on the relation between veridical perceptual experience and hallucination, which I will... (shrink)

1. Overconfidence is usually understood as being more confident than reality justifies (Harvey, 1997; Moore & Healy, 2008; Pompian, 2006), which leads individuals to overestimate their performance...

La littérature du XXe siècle est trop souvent réduite à quelques mouvements littéraires, généralement contestataires. Nous avons voulu rendre hommage à ces chercheurs de l'absolu qui ont profondément marqué leur époque et dont nous voulons montrer l'actualité. Ce recueil d'articles a pour ambition de sonder les nouvelles modalités d'expression d'une parole enthousiaste au moment où l'immanence semble s'imposer. Il s'agit de rendre compte des stratégies employées par les écrivains pour effectuer la transcription langagière d'une forme de transcendance. Au-delà de la (...) thématique générale, nous avons voulu également mettre en lumière des écrivains méconnus qui permettent de porter un regard nouveau sur l'écriture poétique du XXe siècle. (shrink)

The Gifting Logos: Expertise in the Digital Commons provides an extensive analysis of knowledge and creativity in twenty-first century networked culture. Analyzing massive projects like the Wayback Machine, the Internet Archive, and the Creative Commons Licenses, The Gifting Logos responds to a fundamental question, What does it mean to know something and to make something? With the idea of a gifting logos, Hartelius integrates three habits of a rhetorical epistemology: the invention of cultural materials such as text, images, and software; (...) the imbuing or encoding of the materials with the creator's experience; and the constitution and dissemination of the materials as gifts. (shrink)

Insufficient attention has been paid to the ways in which Newtonian conceptualizations of time encourage the view in contemporary psychology that only efficient causal explanations are viable, explanations that ultimately render meaningful, purposive, morally rich human actions and relationships illusory. In short, psychology’s pervasive adoption of Newtonian assumptions about time and causation renders the discipline incapable of understanding human behavior, its primary focus of study, in any but fundamentally inhuman ways. This paper aims (1) to provide a critique of the (...) Newtonian conception of time and its commitment to efficient causality, particularly as commonly present in contemporary psychological theory and practice, and (2) to examine the phenomenological account of time provided in the work of Emmanuel Levinas. Specifically, we will explore some of the ways in which Levinas’ account of time as fundamentally intersubjective provides an alternative conceptual grounding for understanding the therapeutic relationship as one of infinite ethical responsibility. (shrink)

I offer a qualified defence of Kant’s natural teleological argument, that is, his inference from the (un)naturalness of an act to its (im)morality. Though I reject many of Kant’s conclusions, I think the form of argument he uses to support these conclusions is not as wrong-headed as it might at first appear. I consider and answer two objections: first, that the argument is inconsistent with Kant’s moral rationalism; and second, that the argument is inconsistent with post-Kantian developments in science. I (...) argue that both objections rest on a common mistake, namely, the assumption that the account of (human) nature on which Kant’s argument relies is theoretical. On the contrary, the relevant account is practical: informed by science, but not determined by it. Once we appreciate the practical character of Kant’s naturalism, we can see not only that Kant can be a naturalist and a rationalist, but contemporary Kantians can be as well. (shrink)

This book is an ambitious attempt to develop a cognitive approach to religion. Focusing particularly on ritual action, it borrows analytical methods from linguistics and other cognitive sciences. The authors, a philosopher of science and a scholar of comparative religion, provide a lucid critical review of established approaches to the study of religion, and make a strong plea for the combination of interpretation and explanation. Often represented as competitive approaches, they are rather, complementary, equally vital to the study of symbolic (...) systems. (shrink)

Les sociétés découvrent leur vrai visage dès qu'on les observe depuis leurs marges. La figure du mendiant offre, de ce point de vue, un cas idéal. Personnage déclassé et toujours soupçonné d'être un parasite, le mendiant est victime de tous les préjugés, de toutes les violences. Dans la société grecque classique, il est l'anti-modèle de l'homme accompli, que définit son statut de propriétaire terrien, de chef de famille et de citoyen. Mais il en est en même temps le miroir et (...) le révélateur : il lui renvoie ses propres valeurs et ses propres défauts. A travers l'étude de cinq représentations littéraires et philosophiques du mendiant puisées chez Homère, Sophocle, Aristophane, Platon et les cyniques, Etienne Helmer montre comment ce personnage, objet de mépris et de suspicion, est toujours en même temps présenté comme le porte-parole de la vérité, aussi bien sur les plans éthique et politique que métaphysique et anthropologique. Cet ouvrage, le seul en langue française consacré à cette question, n'est pas destiné aux seuls spécialistes de l'Antiquité : il s'inscrit dans un champ de recherches plus large autour de l'une des questions centrales de notre temps. (shrink)

À travers l’analyse de certains aspects du langage de Leonardo Bruni, et en particulier de son utilisation de « popolo » et de « res publica », nous essayons de comprendre dans quelle mesure la politique des premiers humanistes est restée ancrée dans le passé récent de la ville de Florence, malgré les nouveautés idéologiques évidentes (et sans tenir compte de celles d’ordre stylistique et littéraire). En effet, Bruni semble avoir hérité l’idée de la primauté et de l’unité du peuple (...) florentin directement des discours des juristes du XIVe siècle. Par ailleurs, la « respublica»s’avère être, dans ses discours, à la fois une notion tout à fait traditionnelle et l’emblème du processus d’essentialisation d’un peuple reconstitué dans sa dimension universelle grâce à l’expulsion définitive du conflit de l’horizon des possibles. En même temps, en dialogue avec Claudia Moatti notamment, nous essayons de voir comment, avec quels outils, certaines recherches sur l’histoire romaine permettent de saisir les métamorphoses du « peuple » dans une période beaucoup plus tardive. (shrink)