Efforts from diverse disciplines, including evolutionary studies and biomechanical experiments, have yielded new insights into the genetic, signaling, and mechanical control of tooth formation and functions. Evidence from fossils and non‐model organisms has revealed that a common set of genes underlie tooth‐forming potential of epithelia, and changes in signaling environments subsequently result in specialized dentitions, maintenance of dental stem cells, and other phenotypic adaptations. In addition to chemical signaling, tissue forces generated through epithelial contraction, differential growth, and skeletal constraints (...) act in parallel to shape the tooth throughout development. Here recent advances in understanding dental development from these studies are reviewed and important gaps that can be filled through continued application of evolutionary and biomechanical approaches are discussed. (shrink)

How does Newton approach the challenge of mechanizing gravity and, more broadly, natural philosophy? By adopting the simple machine tradition’s mathematical approach to a system’s co-varying parameters of change, he retains natural philosophy’s traditional goal while specifying it in a novel way as the search for impressed forces. He accordingly understands the physical world as a divinely created machine possessing intrinsically mathematical features, and mathematical methods as capable of identifying its real features. The gravitational force’s physical cause remains an (...) outstanding problem, however, as evidenced by Newton’s onetime reference to active principles as the “genuine principles of the mechanical philosophy”. (shrink)

The YAP/TAZ family of transcriptional co‐activators drives cell proliferation in epithelial tissues and cancers. Yet, how YAP and TAZ are physiologically regulated remains unclear. Here we review recent reports that YAP and TAZ act primarily as sensors of epithelial cell polarity, being inhibited when cells differentiate an apical membrane domain, and being activated when cells contact the extracellular matrix via their basal membrane domain. Apical signalling occurs via the canonical Crumbs/CRB‐Hippo/MST‐Warts/LATS kinase cascade to phosphorylate and inhibit YAP/TAZ. Basal signalling occurs (...) via Integrins and Src family kinases to phosphorylate and activate YAP/TAZ. Thus, YAP/TAZ is localised to the nucleus in basal stem/progenitor cells and cytoplasm in differentiated squamous cells or columnar cells. In addition, other signals such as mechanical forces, tissue damage and possibly receptor tyrosine kinases (RTKs) can influence MST‐LATS or Src family kinase activity to modulate YAP/TAZ activity. (shrink)

The remodeling of biological membranes is crucial for a vast number of cellular activities and is an inherently multiscale process in both time and space. Seminal work has provided important insights into nanometer‐scale membrane deformations, and highlighted the remarkable variation and complexity in the underlying molecular machineries and mechanisms. However, how membranes are remodeled at the micron‐scale, particularly in vivo, remains poorly understood. Here, we discuss how using regulated exocytosis of large (1.5–2.0 μm) membrane‐bound secretory granules in the salivary gland (...) of live mice as a model system, has provided evidence for the importance of the actomyosin cytoskeleton in micron‐scale membrane remodeling in physiological conditions. We highlight some of these advances, and present mechanistic hypotheses for how the various biochemical and biophysical properties of distinct actomyosin networks may drive this process. (shrink)

Heinrich Hertz dedicated the last four years of his life to a systematic reformulation of mechanics. One of the main issues that troubled Hertz in the customary formulation of mechanics was a "logical obscurity" in the notion of force. However, it is unclear what this logical obscurity was, hence it is unclear how Hertz took himself to have avoided it. -/- In this paper, I argue that a subtle ambiguity in Newton's original laws of motion lay at the basis (...) of Hertz's concerns; an ambiguity which led to the development of two slightly different notions of force. I then show how Hertz avoided this ambiguity by deriving a unitary notion of force, thus dispelling the obscurity that lurked in the customary representation of mechanics. (shrink)

Correlations of spins in a system of entangled particles are inconsistent with Kolmogorov’s probability theory (KPT), provided the system is assumed to be non-contextual. In the Alice–Bob EPR paradigm, non-contextuality means that the identity of Alice’s spin (i.e., the probability space on which it is defined as a random variable) is determined only by the axis $\alpha _{i}$ chosen by Alice, irrespective of Bob’s axis $\beta _{j}$ (and vice versa). Here, we study contextual KPT models, with two properties: (1) Alice’s (...) and Bob’s spins are identified as $A_{ij}$ and $B_{ij}$ , even though their distributions are determined by, respectively, $\alpha _{i}$ alone and $\beta _{j}$ alone, in accordance with the no-signaling requirement; and (2) the joint distributions of the spins $A_{ij},B_{ij}$ across all values of $\alpha _{i},\beta _{j}$ are constrained by fixing distributions of some subsets thereof. Of special interest among these subsets is the set of probabilistic connections, defined as the pairs $\left( A_{ij},A_{ij'}\right) $ and $\left( B_{ij},B_{i'j}\right) $ with $\alpha _{i}\not =\alpha _{i'}$ and $\beta _{j}\not =\beta _{j'}$ (the non-contextuality assumption is obtained as a special case of connections, with zero probabilities of $A_{ij}\not =A_{ij'}$ and $B_{ij}\not =B_{i'j}$ ). Thus, one can achieve a complete KPT characterization of the Bell-type inequalities, or Tsirelson’s inequalities, by specifying the distributions of probabilistic connections compatible with those and only those spin pairs $\left( A_{ij},B_{ij}\right) $ that are subject to these inequalities. We show, however, that quantum-mechanical (QM) constraints are special. No-forcing theorem says that if a set of probabilistic connections is not compatible with correlations violating QM, then it is compatible only with the classical–mechanical correlations. No-matching theorem says that there are no subsets of the spin variables $A_{ij},B_{ij}$ whose distributions can be fixed to be compatible with and only with QM-compliant correlations. (shrink)

How motor proteins induce mechanical movement at the molecular level has been a focus of biophysicists for a long time. While the whole picture is yet to be completely revealed, recent developments in looking at nanometer‐scale movement with millisecond‐time resolution driven by single motors have revealed important new details about the moving step size and amount of force generated per molecule.

“Pick a card, any card. This has to be a completely free choice.” the magician tells you. But is it really? Although we like to think that we are using our free will to make our decisions, research in psychology has shown that many of our behaviours are automatic and unconsciously influenced by external stimuli (Ariely, 2008; Bargh & Chartrand, 1999; Newell & Shanks, 2014; Nisbett & Wilson, 1977), and that we are often oblivious to the cognitive mechanisms that underpin (...) our decision (Wegner, 2002, 2003). Magicians have exploited this illusory sense of agency for a long time, and have developed a wide range of techniques to influence and control spectators’ choices of such things as card, word, or number (Annemann, 1933; Banachek, 2002a; Jones, 1994; Turner, 2015). These techniques are instances of what is called forcing. -/- Many forces are extremely effective, illustrating various weaknesses in our sense of control over decisions and their outcomes. Researchers have started to investigate them in various ways (Kuhn, Pailh s, & Lan, 2020; Olson, Amlani, Raz, & Rensink, 2015; Pailhes & Kuhn, 2020b, 2020c; Shalom et al., 2013) and are beginning to obtain valuable insights into decision-making processes as well as a better understanding of the cognitive mechanisms that lead people to experience an illusory sense of free will and of agency. -/- Although magicians have acquired large amounts of knowledge in covertly controlling people’s choices, much of this knowledge is only discussed in the context of individual magic tricks, or in books that are not readily accessible to non-magicans. As we and others have argued elsewhere (Ekroll, Sayim, & Wagemans, 2017; Kuhn, 2019; Kuhn, Amlani, & Rensink, 2008; Kuhn, Caffaratti, Teszka, & Rensink, 2014; Macknik et al., 2008; Olson et al., 2015; Olson, Landry, Appourchaux, & Raz, 2016; Shalom et al., 2013; Thomas, Didierjean, Maquestiaux, & Gygax, 2015), a particularly effective way of making this knowledge more available is via the creation of taxonomies centered around psychological mechanisms (Rensink & Kuhn, 2015). For example, the psychologically based taxonomy of misdirection (Kuhn et al., 2014) helps draw links between misdirection and formal theories of perception and cognition. -/- Our aim here is to apply a similar process to the knowledge magicians have about forcing. The present paper develops a psychologically based taxonomy of forcing techniques with two goals in mind. Firstly, it should help uncover the various psychological mechanisms that underlie forcing techniques. Secondly, it should facilitate knowledge transfer between magicians and psychologists. Among other things, this knowledge will allow researchers to gain new insights into the mechanisms underlying decision-making, and the feeling of free will and of agency over choice. We start by defining the magician’s force and then look at some of the past classifications of forcing. (shrink)

The paper deals with the role of the concept of force in different classical mechanical and field theories, pointing out the existence in all cases of a Lorentz-type expression for force. In the case of the classical theory of the gravitational field we obtain the same Lorentz-type expression.

Newtonian forces are pushes and pulls, possessing magnitude and direction, that are exerted (in the first instance) by objects, and which cause (in particular) motions. I defend Newtonian forces against the four best reasons for denying or doubting their existence. A running theme in my defense of forces will be the suggestion that Newtonian Mechanics is a special science, and as such has certain prima facie ontological rights and privileges, that may be maintained against various challenges.

This article discusses the quest for the mechanical advantage of the wedge in the eighteenth century. As a case study, the wedge enlightens our understanding of eighteenth-century mechanics in general and the controversy over “force” or vis viva in particular. In this article, I show that the two different approaches to mechanics, the one that favoured force in terms of velocities and the one that primarily used displacements—known as the ‘Newtonian’ and ‘Leibnizian’ methods, respectively—were not at all (...) on par in their ability to solve the problem of the wedge. In general, only those who used the Leibnizian concept of force or some related notion were able to get to the conventional results. This article thus rebuts the received view that the vis viva controversy was merely a semantic one. Instead, it shows that different understandings of “force” led to real and pragmatic differences in eighteenth-century mechanics. (shrink)

The coupling of protein synthesis and folding is a crucial yet poorly understood aspect of cellular protein folding. Over the past few years, it has become possible to experimentally follow and define protein folding on the ribosome, revealing principles that shape co‐translational folding and distinguish it from refolding in solution. Here, we highlight some of these recent findings from biochemical and biophysical studies and their potential significance for cellular protein biogenesis. In particular, we focus on nascent chain interactions with the (...) ribosome, interactions within the nascent protein, modulation of translation elongation rates, and the role of mechanical force that accompanies nascent protein folding. The ability to obtain mechanistic insight in molecular detail has set the stage for exploring the intricate process of nascent protein folding. We believe that the aspects discussed here will be generally important for understanding how protein synthesis and folding are coupled and regulated. (shrink)

During morphogenesis, tissues undergo extensive remodeling to get their final shape. Such precise sculpting requires the application of forces generated within cells by the cytoskeleton and transmission of these forces through adhesion molecules within and between neighboring cells. Within individual cells, microtubules together with actomyosin filaments and intermediate filaments form the composite cytoskeleton that controls cell mechanics during tissue rearrangements. While studies have established the importance of actin‐based mechanical forces that are coupled via intercellular junctions, relatively little is known (...) about the contribution of other cytoskeletal components such as microtubules to cell mechanics during morphogenesis. In this review the focus is on recent findings, highlighting the direct mechanical role of microtubules beyond its well‐established role in trafficking and signaling during tissue formation. (shrink)

Analysis of grip force signals tailored to hand and finger movement evolution and changes in grip force control during task execution provide unprecedented functional insight into somatosensory cognition. Somatosensory cognition is a basis of our ability to manipulate, move, and transform objects of the physical world around us, to recognize them on the basis of touch alone, and to grasp them with the right amount of force for lifting and manipulating them. Recent technology has permitted the wireless (...) monitoring of grip force signals recorded from biosensors in the palm of the human hand to track and trace human grip forces deployed in cognitive tasks executed under conditions of variable sensory (visual, auditory) input. Non-invasive multi-finger grip force sensor technology can be exploited to explore functional interactions between somatosensory brain mechanisms and motor control, in particular during learning a cognitive task where the planning and strategic execution of hand movements is essential. Sensorial and cognitive processes underlying manual skills and/or hand-specific (dominant versus non-dominant hand) behaviors can be studied in a variety of contexts by probing selected measurement loci in the fingers and palm of the human hand. Thousands of sensor data recorded from multiple spatial locations can be approached statistically to breathe functional sense into the forces measured under specific task constraints. Grip force patterns in individual performance profiling may reveal the evolution of grip force control as a direct result of cognitive changes during task learning. Grip forces can be functionally mapped to from-global-to-local coding principles in brain networks governing somatosensory processes for motor control in cognitive tasks leading to a specific task expertise or skill. Under the light of a comprehensive overview of recent discoveries into the functional significance of human grip force variations, perspectives for future studies in cognition, in particular the cognitive control of strategic and task relevant hand movements in complex real-world precision task, are pointed out. (shrink)

The physical origin of inertial forces is shown to be a consequence of the local interaction of Dirac's real covariant ether model(1) with accelerated microobjects, considered as real extended particlelike solitons, piloted by surrounding subluminal real wave fields packets.(2) Their explicit form results from the application of local inertial Lorentz transformations to the particles submitted to noninertial velocitydependent accelerations, i.e., constitute a natural extension of Lorentz's interpretation of restricted relativity.(3) Indeed Dirac's real physical covariant ether model implies inertial forces if (...) one considers the real accelerated noninertial motions of general relativity, defined within the absolute local inertial frames associated with the observed local isotropy of the 2.7° K background microwave radiation.(4) Inertia thus appears as a necessary consequence of the real particle motions described by the E.d.B.B. formalism of quantum mechanics. (shrink)

Newton’s First Law of Motion is typically understood to govern only the motion of force-free bodies. This paper argues on textual and conceptual grounds that it is in fact a stronger, more general principle. The First Law limits the extent to which any body can change its state of motion –– even if that body is subject to impressed forces. The misunderstanding can be traced back to an error in the first English translation of Newton’s Principia, which was published (...) a few years after Newton’s death. (shrink)

I show how Sir William Rowan Hamilton’s philosophical commitments led him to a causal interpretation of classical mechanics. I argue that Hamilton’s metaphysics of causation was injected into his dynamics by way of a causal interpretation of force. I then detail how forces are indispensable to both Hamilton’s formulation of classical mechanics and what we now call Hamiltonian mechanics (i.e., the modern formulation). On this point, my efforts primarily consist of showing that the contemporary orthodox interpretation of potential energy (...) is the interpretation found in Hamilton’s work. Hamilton called the potential energy function the “force-function” because he believed that it represents forces at work in the world. Various non-historical arguments for this orthodox interpretation of potential energy are provided, and matters are concluded by showing that in classical Hamiltonian mechanics, facts about the potential energies of systems are grounded in facts about forces. Thus, if one can tolerate the view that forces are causes of motion, then Hamilton provides one with a road map for transporting causation into one of the most mathematically sophisticated formulations of classical mechanics, viz., Hamiltonian mechanics. (shrink)

In Descartes’s reformulation of natural philosophy, two aspects of what came to be known as the mechanical philosophy were intimately joined: mechanism as an ontology of nature, according to which all natural things had only ‘mechanical’ properties; and mechanism as a method of explanation. One could, and many philosophers did, adopt mechanism as a method of explanation without adopting a mechanistic ontology. I examine two successors of Descartes who did just that, and one who did not. Giovanni Alfonso (...) Borelli in his De motu animalium and Charles Perrault in his Mécanique de animaux propose and argue for a variety of mechanical accounts of the operations of animals, in particular of their muscles. They reject, however, the Cartesian reduction of animal souls to mechanical forces; the principle of animal motion for them remains a non-mechanical soul. Pierre Sylvain Régis in his Cours entier de philosophie follows Descartes in taking the ‘physical cause’ of motion in animals to be the fermentation of blood in the heart, and thus denies animal souls any role in his physiology. That he can do so while taking over, sometimes word for word, Perrault’s accounts of animal motion shows that mechanistic explanation and mechanistic ontology could easily part company. (shrink)

It is difficult to evaluate the role of activity - of force or of that which has causal efficacy - in Descartes’ natural philosophy. On the one hand, Descartes claims to include in his natural philosophy only that which can be described geometrically, which amounts to matter (extended substance) in motion (where this motion is described kinematically).’ Yet on the other hand, rigorous adherence to a purely geometrical description of matter in motion would make it difficult to account for (...) the interactions among the particles that constitute Descartes’ universe, since the notions of extension and kinematical motion do not in themselves imply any causal agency. There is, after all, no reason to expect that a particle whose single essence is extension, even if we suppose it to be moving, should impart motion to another particle, while conversely, there is no reason to expect a resting particle to hinder the motion of an impinging one. Descartes' hankering for an austere ontology of matter in motion is in danger of excluding causal agency (force, conceived dynmically) from matter. To the modern reader it may seem obvious that Descartes did not get himself into such a fix, since matter in motion so readily reminds us of kinetic energy or of some more primitive notion of force. Yet by no means is it obvious that Descartes attributed causal efficacy to matter in motion per se. Serious scholars have held opposite positions on this issue. Westfall, Gabbey, and others’ have argued that although on the metaphysical plane Descartes attempted to eliminate force from his mechanical universe, nonetheless ‘force is a real feature’ of his mechanical world. The thrust of this view is that Descartes conceived of force as ‘the capacity of a body in motion to act’, by means of impact, upon other bodies. An opposing interpretation, defended here, is that Descartes did in fact deny causal agency to moving matter per se, restricting agency to immaterial substances such as the human mind, angels, and God. The intention of this interpretation is not to de-emphasize the role of matter in motion in Descartes’ explanation of nature, but rather to stress the fact that Descartes did not conceive of this moving matter dynamically. -/- Reprinted in Descartes, ed. by J. Cottingham, Oxford Readings in Philosophy (Oxford: Oxford University Press, 1998), 281–310. (shrink)

This study's objective is to explore the psychological defense mechanisms of Ukrainian service members as a regulatory system for personality stabilization that influences combat mission effectiveness. The study was carried out during 2019–2020. The respondents were 270 military personnel of the ground forces, who had gained experience in the Anti-Terrorist Operation hostilities in the East of Ukraine in 2017–2020. We used psychodiagnostic methods such as the Lifestyle Index by Plutchik, Kellerman, and Conte; Lazarus’s Coping Test; and Leontiev’s Meaningful Life Orientations (...) Test. Our work confirmed our research hypothesis that psychological defense mechanisms as part of the regulatory system of personality stabilization predetermine the effectiveness of the combat missions performed by military personnel of special branches. Military psychologists can use the results during their official training (psychological training and psycho-corrective measures) in order to acquire among the troops the required effectiveness in combat. Defense mechanisms will also contribute to the observance of military ethics, not least when faced with military immorality on the part of adversaries. (shrink)

The operation of fundamental forces in quantum field theory is explicated here as the exchange of particles, consistently with the standard methodology of particle physics. The particles involved are seen to bear little relation to any classical particle but, rather, comprise unified collections of compresent, conserved quantities indicated by propagators. The exchange particles, which supervene upon quantum fields, are neither more fundamental than fields nor replace them as has often previously been assumed in models of exchange forces. It is argued (...) that this explication of quantum field-theoretic exchange forces definitively improves upon its predecessors. (shrink)

In this paper I discuss two questions. What does Kant understand by mechanical explanation in the Critique of judgment? And why does he think that mechanical explanation is the only type of the explanation of nature available to us? According to the interpretation proposed, mechanical explanations in the Critique of judgment refer to a particular species of empirical causal laws. Mechanical laws aim to explain nature by reference to the causal interaction between the forces of the (...) parts of matter and the way in which they form into complex material wholes. Just like any other empirical causal law, however, mechanical laws can never be known with full certainty. The conception according to which we can explain all of nature by means of mechanical laws, it turns out, is based on what Kant calls ‘regulative’ or ‘reflective’ considerations about nature. Nothing in Kant’s Critique of judgment suggests that these considerations can ever be justified by reference to how the natural world really is. I suggest that what, upon first consideration, appears to be a thoroughly mechanistic conception of nature in Kant is much more limited than one might have expected. (shrink)

This article discusses the quest for the mechanical advantage of the wedge in the eighteenth century. As a case study, the wedge enlightens our understanding of eighteenth-century mechanics in general and the controversy over “force” or vis viva in particular. In this article, I show that the two different approaches to mechanics, the one that favoured force in terms of velocities and the one that primarily used displacements—known as the ‘Newtonian’ and ‘Leibnizian’ methods, respectively—were not at all (...) on par in their ability to solve the problem of the wedge. In general, only those who used the Leibnizian concept of force or some related notion were able to get to the conventional results. This article thus rebuts the received view that the vis viva controversy was merely a semantic one. Instead, it shows that different understandings of “force” led to real and pragmatic differences in eighteenth-century mechanics. (shrink)

The sense of touch informs us of the physical properties of our surroundings and is a critical aspect of communication. Before touches are perceived, mechanical signals are transmitted quickly and reliably from the skin's surface to mechano‐electrical transduction channels embedded within specialized sensory neurons. We are just beginning to understand how soft tissues participate in force transmission and how they are deformed. Here, we review empirical and theoretical studies of single molecules and molecular ensembles thought to be involved (...) in mechanotransmission and apply the concepts emerging from this work to the sense of touch. We focus on the nematode Caenorhabditis elegans as a well‐studied model for touch sensation in which mechanics can be studied on the molecular, cellular, and systems level. Finally, we conclude that force transmission is an emergent property of macromolecular cellular structures that mutually stabilize one another. (shrink)

In this paper, I critically assess different interpretations of Bohmian mechanics that are not committed to an ontology based on the wave function being an actual physical object that inhabits configuration space. More specifically, my aim is to explore the connection between the denial of configuration space realism and another interpretive debate that is specific to Bohmian mechanics: the quantum potential versus guidance approaches. Whereas defenders of the quantum potential approach to the theory claim that Bohmian mechanics is better formulated (...) as quasi-Newtonian, via the postulation of forces proportional to acceleration; advocates of the guidance approach defend the notion that the theory is essentially first-order and incorporates some concepts akin to those of Aristotelian physics. Here I analyze whether the desideratum of an interpretation of Bohmian mechanics that is both explanatorily adequate and not committed to configuration space realism favors one of these two approaches to the theory over the other. Contrary to some recent claims in the literature, I argue that the quasi-Newtonian approach based on the idea of a quantum potential does not come out the winner. (shrink)

This history of physics focuses on the question, "How do bodies act on one another across space?" The variety of answers illustrates the function of fundamental analogies or models in physics as well as the role of so-called unobservable entities. Forces and Fields presents an in-depth look at the science of ancient Greece, and it examines the influence of antique philosophy on seventeenth-century thought. Additional topics embrace many elements of modern physics--the empirical basis of quantum mechanics, wave-particle duality and the (...) uncertainty principle, and the action-at-a-distance theory of Wheeler and Feynman. 1961 ed. (shrink)

Why does one theory "succeed" while another, possibly clearer interpretation, fails? By exploring two observationally equivalent yet conceptually incompatible views of quantum mechanics, James T. Cushing shows how historical contingency can be crucial to determining a theory's construction and its position among competing views. Since the late 1920s, the theory formulated by Niels Bohr and his colleagues at Copenhagen has been the dominant interpretation of quantum mechanics. Yet an alternative interpretation, rooted in the work of Louis de Broglie in the (...) early 1920s and reformulated and extended by David Bohm in the 1950s, equally well explains the observational data. Through a detailed historical and sociological study of the physicists who developed different theories of quantum mechanics, the debates within and between opposing camps, and the receptions given to each theory, Cushing shows that despite the preeminence of the Copenhagen view, the Bohm interpretation cannot be ignored. Cushing contends that the Copenhagen interpretation became widely accepted not because it is a better explanation of subatomic phenomena than is Bohm's, but because it happened to appear first. Focusing on the philosophical, social, and cultural forces that shaped one of the most important developments in modern physics, this provocative book examines the role that timing can play in the establishment of theory and explanation. (shrink)

Newtonian mechanics is more than just an empirically successful theory of matter in motion: it is an account of what knowledge of the physical world should look like. But what is this account? What is distinctive about it? To answer these questions, I begin by introducing the laws of motion, the relations among them, and the spatio-temporal framework that is implicit in them. Then I turn to the question of their methodological character. This has been the locus of philosophical discussion (...) from Newton’s time to the present, and I survey the views of some of the major contributors. I show that while Newtonian mechanics motivates a number of philosophical ideas about force, mass, motion, and causality – and through this, ideas about space and time – the laws are themselves the outcome of a philosophical or critical conceptual analysis. (shrink)

Stalnaker’s Context deploys the core machinery of common ground, possible worlds, and epistemic accessibility to mount a powerful case for the ‘autonomy of pragmatics’: the utility of theorizing about discourse function independently of specific linguistic mechanisms. Illocutionary force lies at the peripherybetween pragmatics—as the rational, non-conventional dynamics of context change—and semantics—as a conventional compositional mechanism for determining truth-conditional contents—in an interesting way. I argue that the conventionalization of illocutionary force, most notably in assertion, has important crosscontextual consequences that (...) are not fully captured by a specification of dynamic effects on common ground. More generally, I suggest that Stalnaker’s purely informational, propositional analysis of both semantic content and dynamic effects distorts our understanding of the function of language, especially of the real-world commitments and consequences engendered by robustly ‘expressive’ language like slurs, honorifics, and thick terms. (shrink)

Reprint of: Gary Hatfield, Force (God) in Descartes' physics, Studies in History and Philosophy of Science Part A 10 (2):113-140 (1979) -/- Abstract. It is difficult to evaluate the role of activity - of force or of that which has causal efficacy - in Descartes’ natural philosophy. On the one hand, Descartes claims to include in his natural philosophy only that which can be described geometrically, which amounts to matter (extended substance) in motion (where this motion is described (...) kinematically).’ Yet on the other hand, rigorous adherence to a purely geometrical description of matter in motion would make it difficult to account for the interactions among the particles that constitute Descartes’ universe, since the notions of extension and kinematical motion do not in themselves imply any causal agency. There is, after all, no reason to expect that a particle whose single essence is extension, even if we suppose it to be moving, should impart motion to another particle, while conversely, there is no reason to expect a resting particle to hinder the motion of an impinging one. Descartes' hankering for an austere ontology of matter in motion is in danger of excluding causal agency (force, conceived dynmically) from matter. To the modern reader it may seem obvious that Descartes did not get himself into such a fix, since matter in motion so readily reminds us of kinetic energy or of some more primitive notion of force. Yet by no means is it obvious that Descartes attributed causal efficacy to matter in motion per se. Serious scholars have held opposite positions on this issue. Westfall, Gabbey, and others’ have argued that although on the metaphysical plane Descartes attempted to eliminate force from his mechanical universe, nonetheless ‘force is a real feature’ of his mechanical world. The thrust of this view is that Descartes conceived of force as ‘the capacity of a body in motion to act’, by means of impact, upon other bodies. An opposing interpretation, defended here, is that Descartes did in fact deny causal agency to moving matter per se, restricting agency to immaterial substances such as the human mind, angels, and God. The intention of this interpretation is not to de-emphasize the role of matter in motion in Descartes’ explanation of nature, but rather to stress the fact that Descartes did not conceive of this moving matter dynamically. (shrink)

Here I explore a novel no-collapse interpretation of quantum mechanics that combines aspects of two familiar and well-developed alternatives, Bohmian mechanics and the many-worlds interpretation. Despite reproducing the empirical predictions of quantum mechanics, the theory looks surprisingly classical. All there is at the fundamental level are particles interacting via Newtonian forces. There is no wave function. However, there are many worlds.

Quantum mechanics (QM) predicts probabilities on the fundamental level which are, via Born probability law, connected to the formal randomness of infinite sequences of QM outcomes. Recently it has been shown that QM is algorithmic 1-random in the sense of Martin–Löf. We extend this result and demonstrate that QM is algorithmic $$\omega$$ -random and generic, precisely as described by the ’miniaturisation’ of the Solovay forcing to arithmetic. This is extended further to the result that QM becomes Zermelo–Fraenkel Solovay random on (...) infinite-dimensional Hilbert spaces. Moreover, it is more likely that there exists a standard transitive ZFC model M, where QM is expressed in reality, than in the universe V of sets. Then every generic quantum measurement adds to M the infinite sequence, i.e. random real $$r\in 2^{\omega }$$, and the model undergoes random forcing extensions M[r]. The entire process of forcing becomes the structural ingredient of QM and parallels similar constructions applied to spacetime in the quantum limit, therefore showing the structural resemblance of both in this limit. We discuss several questions regarding measurability and possible practical applications of the extended Solovay randomness of QM. The method applied is the formalization based on models of ZFC; however, this is particularly well-suited technique to recognising randomness questions of QM. When one works in a constant model of ZFC or in axiomatic ZFC itself, the issues considered here remain hidden to a great extent. (shrink)

The concept of force can seem comparatively unproblematic—forces are responsible for making things move. However, the history of both physics and metaphysics reveals considerable controversy concerning both the nature of forces, and their very existence. My survey takes in the Greek atomists, Aristotelian physics, the “mechanical” philosophy of the scientific revolution, the innovations of Descartes and Newton, Hume-inspired skepticism, the dynamism of Leibniz, Kant and Boscovich, the field theories of Faraday and Maxwell, and the impact of Einstein’s relativity (...) theories and quantum mechanics. A recurring theme is the contrasting attitudes taken towards “action at a distance” causal influences by both philosophers and scientists. (shrink)

New research demonstrates that mechanics can serve as a means of information propagation in developing embryos. Historically, the study of embryonic development has had a dichotomy between morphogens and pattern formation on the one hand and morphogenesis and mechanics on the other. Secreted signals are the preeminent means of information propagation between cells and used to control cell fate, while physical forces act downstream or in parallel to shape tissue morphogenesis. However, recent work has blurred this division of function by (...) demonstrating that mechanics can serve as a means of information propagation. Adhesive or repulsive interactions can propagate through a tissue as a wave. These waves are rapid and directional and can be used to control the flux of cells through a developmental trajectory. Here, two examples are reviewed in which mechanics both guides and mediates morphogenesis and two examples in which mechanics intertwines with morphogens to regulate cell fate. (shrink)

How environmental mechanical forces affect cellular functions is a central problem in cell biology. Theoretical models of cellular biomechanics provide relevant tools for understanding how the contributions of deformable intracellular components and specific adhesion conditions at the cell interface are integrated for determining the overall balance of mechanical forces within the cell. We investigate here the spatial distributions of intracellular stresses when adherent cells are probed by magnetic twisting cytometry. The influence of the cell nucleus stiffness on the (...) simulated nonlinear torque-bead rotation response is analyzed by considering a finite element multi-component cell model in which the cell and its nucleus are considered as different hyperelastic materials. We additionally take into account the mechanical properties of the basal cell cortex, which can be affected by the interaction of the basal cell membrane with the extracellular substrate. In agreement with data obtained on epithelial cells, the simulated behaviour of the cell model relates the hyperelastic response observed at the entire cell scale to the distribution of stresses and strains within the nucleus and the cytoskeleton, up to cell adhesion areas. These results, which indicate how mechanical forces are transmitted at distant points through the cytoskeleton, are compared to recent data imaging the highly localized distribution of intracellular stresses. (shrink)

This article focuses on the theory of solidarity presented by Émile Durkheim in The Division of Labour in Society ([1893] 1969). Despite its popularity, the distinction between mechanical and organic solidarity has received a lot of criticism. Durkheim allegedly was unable to demonstrate the superior integrating force of modern organic solidarity, while this was his central thesis at the time. A second critique challenges his macrostructural point of view. However, by confronting Durkheim’s classical theory with contemporary work, notably (...) Honneth’s theory of recognition, we can deduce a reformulated framework that is less vulnerable to the afore-mentioned critiques. On the one hand, we specify mechanical and organic solidarity as a dialectical synthesis of both internalized universalistic principles and particularistic emotional orientations. On the other, we incorporate the foregoing typology in a cyclical model that implies interacting processes of inclusion and individualization. (shrink)

Non-commuting quantities and hidden parameters – Wave-corpuscular dualism and hidden parameters – Local or nonlocal hidden parameters – Phase space in quantum mechanics – Weyl, Wigner, and Moyal – Von Neumann’s theorem about the absence of hidden parameters in quantum mechanics and Hermann – Bell’s objection – Quantum-mechanical and mathematical incommeasurability – Kochen – Specker’s idea about their equivalence – The notion of partial algebra – Embeddability of a qubit into a bit – Quantum computer is not Turing machine (...) – Is continuality universal? – Diffeomorphism and velocity – Einstein’s general principle of relativity – „Mach’s principle“ – The Skolemian relativity of the discrete and the continuous – The counterexample in § 6 of their paper – About the classical tautology which is untrue being replaced by the statements about commeasurable quantum-mechanical quantities – Logical hidden parameters – The undecidability of the hypothesis about hidden parameters – Wigner’s work and и Weyl’s previous one – Lie groups, representations, and psi-function – From a qualitative to a quantitative expression of relativity − psi-function, or the discrete by the random – Bartlett’s approach − psi-function as the characteristic function of random quantity – Discrete and/ or continual description – Quantity and its “digitalized projection“ – The idea of „velocity−probability“ – The notion of probability and the light speed postulate – Generalized probability and its physical interpretation – A quantum description of macro-world – The period of the as-sociated de Broglie wave and the length of now – Causality equivalently replaced by chance – The philosophy of quantum information and religion – Einstein’s thesis about “the consubstantiality of inertia ant weight“ – Again about the interpretation of complex velocity – The speed of time – Newton’s law of inertia and Lagrange’s formulation of mechanics – Force and effect – The theory of tachyons and general relativity – Riesz’s representation theorem – The notion of covariant world line – Encoding a world line by psi-function – Spacetime and qubit − psi-function by qubits – About the physical interpretation of both the complex axes of a qubit – The interpretation of the self-adjoint operators components – The world line of an arbitrary quantity – The invariance of the physical laws towards quantum object and apparatus – Hilbert space and that of Minkowski – The relationship between the coefficients of -function and the qubits – World line = psi-function + self-adjoint operator – Reality and description – Does a „curved“ Hilbert space exist? – The axiom of choice, or when is possible a flattening of Hilbert space? – But why not to flatten also pseudo-Riemannian space? – The commutator of conjugate quantities – Relative mass – The strokes of self-movement and its philosophical interpretation – The self-perfection of the universe – The generalization of quantity in quantum physics – An analogy of the Feynman formalism – Feynman and many-world interpretation – The psi-function of various objects – Countable and uncountable basis – Generalized continuum and arithmetization – Field and entanglement – Function as coding – The idea of „curved“ Descartes product – The environment of a function – Another view to the notion of velocity-probability – Reality and description – Hilbert space as a model both of object and description – The notion of holistic logic – Physical quantity as the information about it – Cross-temporal correlations – The forecasting of future – Description in separable and inseparable Hilbert space – „Forces“ or „miracles“ – Velocity or time – The notion of non-finite set – Dasein or Dazeit – The trajectory of the whole – Ontological and onto-theological difference – An analogy of the Feynman and many-world interpretation − psi-function as physical quantity – Things in the world and instances in time – The generation of the physi-cal by mathematical – The generalized notion of observer – Subjective or objective probability – Energy as the change of probability per the unite of time – The generalized principle of least action from a new view-point – The exception of two dimensions and Fermat’s last theorem. (shrink)

This paper defends the view that Newtonian forces are real, symmetrical and non-causal relations. First, I argue that Newtonian forces are real; second, that they are relations; third, that they are symmetrical relations; fourth, that they are not species of causation. The overall picture is anti-Humean to the extent that it defends the existence of forces as external relations irreducible to spatio-temporal ones, but is still compatible with Humean approaches to causation (and others) since it denies that forces are a (...) species of causation. (shrink)

According to phenomenal conservatism or dogmatism, perceptual experiences can give us immediate justification for beliefs about the external world in virtue of having a distinctive kind of phenomenal character—namely phenomenal force. I present three cases to show that phenomenal force is neither pervasive among nor exclusive to perceptual experiences. The plausibility of such cases calls out for explanation. I argue that contrary to a long-held assumption, phenomenal force is a separate, non-perceptual state generated by some metacognitive mechanisms (...) that monitor one’s first-order mental processes and states. This new account advances our understanding of the nature of phenomenal force. (shrink)

We develop and defend the thesis that the Hilbert space formalism of quantum mechanics is a new theory of probability. The theory, like its classical counterpart, consists of an algebra of events, and the probability measures defined on it. The construction proceeds in the following steps: (a) Axioms for the algebra of events are introduced following Birkhoff and von Neumann. All axioms, except the one that expresses the uncertainty principle, are shared with the classical event space. The only models for (...) the set of axioms are lattices of subspaces of inner product spaces over a field K. (b) Another axiom due to Soler forces K to be the field of real, or complex numbers, or the quaternions. We suggest a probabilistic reading of Soler's axiom. (c) Gleason's theorem fully characterizes the probability measures on the algebra of events, so that Born's rule is derived. (d) Gleason's theorem is equivalent to the existence of a certain finite set of rays, with a particular orthogonality graph (Wondergraph). Consequently, all aspects of quantum probability can be derived from rational probability assignments to finite "quantum gambles". (e) All experimental aspects of entanglement- the violation of Bell's inequality in particular- are explained as natural outcomes of the probabilistic structure. (f) We hypothesize that even in the absence of decoherence macroscopic entanglement can very rarely be observed, and provide a precise conjecture to that effect .We also discuss the relation of the present approach to quantum logic, realism and truth, and the measurement problem. (shrink)

This paper defends a realist account of the composition of Newtonian forces, dubbed ‘residualism’. According to residualism, the resultant force acting on a body is identical to the component forces acting on it that do not prevent each other from bringing about its acceleration. Several reasons to favor residualism over alternative accounts of the composition of forces are advanced. (i) Residualism reconciles realism about component forces with realism about resultant forces while avoiding any threat of causal overdetermination. (ii) Residualism (...) provides a systematic semantics for the term ‘force’ within Newtonian mechanics. (iii) Residualism allows us to precisely apportion the causal responsibility of each component force in the ensuing acceleration. (iv) Residualism handles special cases such as null forces, single forces, and antagonistic forces in a natural way. (v) Residualism provides a neat picture of the causal powers of forces: each force essentially has two causal powers⎯the power to bring about accelerations (sometimes together with other co-directionnal forces) and the power to prevent other forces from doing so⎯exactly one of which is manifested at a time. (vi) Residualism avoids commitment to unobservable effects of forces: forces cause either stresses (tensile or compressive) or accelerations. (shrink)

We address a long-standing debate over whether classical magnetic forces can do work, ultimately answering the question in the affirmative. In detail, we couple a classical particle with intrinsic spin and elementary dipole moments to the electromagnetic field, derive the appropriate generalization of the Lorentz force law, show that the particle's dipole moments must be collinear with its spin axis, and argue that the magnetic field does mechanical work on the particle's elementary magnetic dipole moment. As consistency checks, (...) we calculate the overall system's energy-momentum and angular momentum, and show that their local conservation equations lead to the same force law and therefore the same conclusions about magnetic forces and work. We also compute the system's Belinfante-Rosenfeld energy-momentum tensor. (shrink)

In this work, a neo-classical relativistic mechanics theory is presented where the spin of an electron is an inherent part of its world space-time path as a point particle. The fourth-order equation of motion corresponds to the same covariant Lagrangian function in proper time as in special relativity except for an additional spin energy term. The theory provides a hidden-variable model of the electron where the dynamic variables give a complete description of its motion, giving a classical mechanics explanation of (...) the electron’s spin, its dipole moments, and Schrödinger’s zitterbewegung, These features are also described mathematically by quantum mechanics theory, of course, but without any physical picture of an underlying reality. The total motion of the electron can be decomposed into a sum of a local spin motion about a point and a global motion of this point, called here the spin center. The global motion is sub-luminal and described by Newton’s Second Law in proper time, the time for a clock fixed at the spin center, while the total motion occurs at the speed of light c, consistent with the eigenvalues of Dirac’s velocity operators having magnitude c. The local spin motion is an inherent perpetual motion, which for a free electron is periodic at the ultra-high zitterbewegung frequency and its path is circular in a spin-center reference frame. In an electro-magnetic field, this spin motion generates magnetic and electric dipole energies through the Lorentz force on the electron’s point charge. The electric dipole energy corresponds to the spin-orbit coupling term involving the electric field that appears in the corrected Pauli non-relativistic Hamiltonian, which has long been used to explain the doublet structure of the spectral lines of the excited hydrogen atom. Pauli’s spin-orbit term is usually derived, however, from his magnetic dipole energy term, including also the effect of Thomas precession, which halves this energy. The magnetic dipole energy from Pauli’s and Dirac’s theory is twice that in the neo-classical theory, a discrepancy that has not been resolved. By defining a spin tensor as the angular momentum of the electron’s total motion about its spin center, the fundamental equations of motion can be re-written in an identical form to those of the Barut–Zanghi electron theory. This allows the equations of motion to be expressed in an equivalent form involving operators applied to a state function of proper time satisfying a neo-classical Dirac–Schrödinger spinor equation. This state function produces the dynamic variables from the same operators as in Dirac’s theory for the electron but without any probability implications. It leads to a neo-classical wave function that satisfies Dirac’s relativistic wave equation for the free electron by applying the Lorentz transformation to express proper time in the state function in terms of an observer’s space-time coordinates, showing that there is a close connection between the neo-classical theory and quantum mechanics theory for the electron’s dynamics. (shrink)

This is an encyclopedia entry on the notion of force as entering into physical science.