65 found
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  1.  73
    Cortical Midline Structures and the Self.Georg Northoff & Felix Bermpohl - 2004 - Trends in Cognitive Sciences 8 (3):102-107.
  2. Personal Identity and Brain Identity.Nils-Frederic Wagner & Georg Northoff - 2017 - In L. Syd M. Johnson & Karen Rommelfanger (eds.), The Routledge Handbook of Neuroethics. Routledge. pp. 335-351.
  3. Resting State Glutamate Predicts Elevated Pre-Stimulus Alpha During Self-Relatedness: A Combined EEG-MRS Study on 'Rest-Self' Overlap.Yu Bai, Timothy Lane, Georg Northoff & et al - 2015 - Social Neuroscience:DOI:10.1080/17470919.2015.107258.
    Recent studies have demonstrated neural overlap between resting state activity and self-referential processing. This “rest-self” overlap occurs especially in anterior cortical midline structures like the perigenual anterior cingulate cortex (PACC). However, the exact neurotemporal and biochemical mechanisms remain to be identified. Therefore, we conducted a combined electroencephalography (EEG)-magnetic resonance spectroscopy (MRS) study. EEG focused on pre-stimulus (e.g., prior to stimulus presentation or perception) power changes to assess the degree to which those changes can predict subjects’ perception (and judgment) of subsequent (...)
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  4.  59
    The Trans-Species Concept of Self and the Subcortical–Cortical Midline System.Georg Northoff & Jaak Panksepp - 2008 - Trends in Cognitive Sciences 12 (7):259-264.
  5.  11
    Editorial: The Janus Face of Language: Where Are the Emotions in Words and Where Are the Words in Emotions?Cornelia Herbert, Thomas Ethofer, Andreas J. Fallgatter, Peter Walla & Georg Northoff - 2018 - Frontiers in Psychology 9.
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  6.  97
    Brain Imaging of the Self–Conceptual, Anatomical and Methodological Issues.Georg Northoff, Pengmin Qin & Todd E. Feinberg - 2011 - Consciousness and Cognition 20 (1):52–63.
    In this paper we consider two major issues: conceptual–experimental approaches to the self, and the neuroanatomical substrate of the self. We distinguish content- and processed-based concepts of the self that entail different experimental strategies, and anatomically, we investigate the concept of midline structures in further detail and present a novel view on the anatomy of an integrated subcortical–cortical midline system. Presenting meta-analytic evidence, we show that the anterior paralimbic, e.g. midline, regions do indeed seem to be specific for self-specific stimuli. (...)
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  7. Philosophy of the Brain: The Brain Problem.Georg Northoff - 2004 - John Benjamins.
  8.  50
    Immanuel Kant's Mind and the Brain's Resting State.Georg Northoff - 2012 - Trends in Cognitive Sciences 16 (7):356-359.
  9. The Trajectory of Self.Timothy Lane, Niall W. Duncan, Tony Cheng & Georg Northoff - 2016 - Trends in Cognitive Sciences 20 (7):481-482.
    In a recent Opinion article, Sui and Humphreys [1] argue that experimental findings suggest self is ‘special’, in that self-reference serves a binding function within human cognitive economy. Contrasting their view with other functionalist positions, chiefly Dennett's [2], they deny that self is a convenient fiction and adduce findings to show that a ‘core self representation’ serves as an ‘integrative glue’ helping to bind distinct types of information as well as distinct stages of psycho- logical processing. In other words, where (...)
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  10.  23
    Neuroscience and Whitehead I: Neuro-Ecological Model of Brain.Georg Northoff - 2016 - Axiomathes 26 (3):219-252.
    Neuroscience has made enormous progress in understanding the brain and its various neuro-sensory and neuro-cognitive functions. However, despite all progress, the model of the brain as well as its ontological characterization remain unclear. The aim in this first paper is the discussion of an empirically plausible model of the brain with the subsequent claim of a neuro-ecological model. Whitehead claimed that he inversed or reversed the Kantian notion of the subject by putting it back into the ecological context of the (...)
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  11.  13
    Temporal Limits on Rubber Hand Illusion Reflect Individuals’ Temporal Resolution in Multisensory Perception.Marcello Costantini, Jeffrey Robinson, Daniele Migliorati, Brunella Donno, Francesca Ferri & Georg Northoff - 2016 - Cognition 157:39-48.
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  12.  15
    How to Link Brain and Experience? Spatiotemporal Psychopathology of the Lived Body.Georg Northoff & Giovanni Stanghellini - 2016 - Frontiers in Human Neuroscience 10.
  13. Spontaneous Activity in Default-Mode Network Predicts Ascriptions of Self-Relatedness to Stimuli.Pengmin Qin, Georg Northoff, Timothy Lane & et al - 2016 - Social Cognitive and Affective Neuroscience:xx-yy.
    Spontaneous activity levels prior to stimulus presentation can determine how that stimulus will be perceived. It has also been proposed that such spontaneous activity, particularly in the default-mode network (DMN), is involved in self-related processing. We therefore hypothesised that pre-stimulus activity levels in the DMN predict whether a stimulus is judged as self-related or not. Method: Participants were presented in the MRI scanner with a white noise stimulus that they were instructed contained their name or another. They then had to (...)
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  14.  8
    Is Anorexia Nervosa a Disorder of the Self? A Psychological Approach.Federico Amianto, Georg Northoff, Giovanni Abbate Daga, Secondo Fassino & Giorgio A. Tasca - 2016 - Frontiers in Psychology 7.
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  15. Is Depressive Rumination Rational?Timothy Lane & Georg Northoff - 2016 - In T. W. Hung & T. J. Lane (eds.), Rationality: Constraints and Contexts. Oxford, UK: Elsevier. pp. 121-145.
    Most mental disorders affect only a small segment of the population. On the reasonable assumption that minds or brains are prone to occasional malfunction, these disorders do not seem to pose distinctive explanatory problems. Depression, however, because it is so prevalent and costly, poses a conundrum that some try to explain by characterizing it as an adaptation—a trait that exists because it performed fitness-enhancing functions in ancestral populations. Heretofore, proposed evolutionary explanations of depression did not focus on thought processes; instead, (...)
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  16.  44
    A Fallacious Jar? The Peculiar Relation Between Descriptive Premises and Normative Conclusions in Neuroethics.Nils-Frederic Wagner & Georg Northoff - 2015 - Theoretical Medicine and Bioethics 36 (3):215-235.
    Ethical questions have traditionally been approached through conceptual analysis. Inspired by the rapid advance of modern brain imaging techniques, however, some ethical questions appear in a new light. For example, hotly debated trolley dilemmas have recently been studied by psychologists and neuroscientists alike, arguing that their findings can support or debunk moral intuitions that underlie those dilemmas. Resulting from the wedding of philosophy and neuroscience, neuroethics has emerged as a novel interdisciplinary field that aims at drawing conclusive relationships between neuroscientific (...)
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  17. GABAA Receptor Deficits Predict Recovery in Patients With Disorders of Consciousness: A Preliminary Multimodal [11C]Flumazenil PET and fMRI Study.Pengmin Qin, Georg Northoff, Timothy Lane & et al - 2015 - Human Brain Mapping:DOI: 10.1002/hbm.22883.
    Disorders of consciousness (DoC)—that is, unresponsive wakefulness syndrome/vegetative state and minimally conscious state—are debilitating conditions for which no reliable markers of consciousness recovery have yet been identified. Evidence points to the GABAergic system being altered in DoC, making it a potential target as such a marker.
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  18. The Trans-Species Core SELF: The Emergence of Active Cultural and Neuro-Ecological Agents Through Self-Related Processing Within Subcortical-Cortical Midline Networks.Jaak Panksepp & Georg Northoff - 2009 - Consciousness and Cognition 18 (1):193–215.
    The nature of “the self” has been one of the central problems in philosophy and more recently in neuroscience. This raises various questions: Can we attribute a self to animals? Do animals and humans share certain aspects of their core selves, yielding a trans-species concept of self? What are the neural processes that underlie a possible trans-species concept of self? What are the developmental aspects and do they result in various levels of self-representation? Drawing on recent literature from both human (...)
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  19.  31
    Neuroscience and Whitehead II: Process-Based Ontology of Brain.Georg Northoff - 2016 - Axiomathes 26 (3):253-277.
    While neuroscience has made enormous progress in understanding the brain, the implications of these empirical findings for ontological questions in philosophy including the mind–body problem remain yet unclear. In the first paper, I discussed the model of brain that as implied and supported by the empirical data. This leads me now to the question of an empirically plausible ontology of brain. Therefore, the aim in this second paper is the ontological characterization of the brain in terms of a process-based ontology (...)
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  20.  52
    Habits: Bridging the Gap Between Personhood and Personal Identity.Nils-Frederic Wagner & Georg Northoff - 2014 - Frontiers in Human Neuroscience 8.
    In philosophy, the criteria for personhood (PH) at a specific point in time (synchronic), and the necessary and sufficient conditions of personal identity (PI) over time (diachronic) are traditionally separated. Hence, the transition between both timescales of a person's life remains largely unclear. Personal habits reflect a decision-making (DM) process that binds together synchronic and diachronic timescales. Despite the fact that the actualization of habits takes place synchronically, they presuppose, for the possibility of their generation, time in a diachronic sense. (...)
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  21. Too Fast or Too Slow? Time and Neuronal Variability in Bipolar Disorder—A Combined Theoretical and Empirical Investigation.Timothy Lane & Georg Northoff - forthcoming - Schizophrenia Bulletin 43.
    Time is an essential feature in bipolar disorder (BP). Manic and depressed BP patients perceive the speed of time as either too fast or too slow. The present article combines theoretical and empirical approaches to integrate phenomenological, psychological, and neuroscientific accounts of abnormal time perception in BP. Phenomenology distinguishes between perception of inner time, ie, self-time, and outer time, ie, world-time, that desynchronize or dissociate from each other in BP: inner time speed is abnormally slow (as in depression) or fast (...)
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  22.  16
    Is Our Self Related to Personality? A Neuropsychodynamic Model.Andrea Scalabrini, Clara Mucci & Georg Northoff - 2018 - Frontiers in Human Neuroscience 12.
  23.  31
    Self and Brain: What is Self-Related Processing?Georg Northoff - 2011 - Trends in Cognitive Sciences 15 (5):186-187.
  24.  25
    Integrative Processing of Touch and Affect in Social Perception: An fMRI Study.Sjoerd J. H. Ebisch, Anatolia Salone, Giovanni Martinotti, Leonardo Carlucci, Dante Mantini, Mauro G. Perrucci, Aristide Saggino, Gian Luca Romani, Massimo Di Giannantonio, Georg Northoff & Vittorio Gallese - 2016 - Frontiers in Human Neuroscience 10.
  25.  41
    Is Emotion Regulation Self-Regulation?Georg Northoff - 2005 - Trends in Cognitive Sciences 9 (9):408-409.
  26. Kripke's Modal Argument is Challenged by His Implausible Conception of Introspection.Alexander Heinzel & Georg Northoff - 2009 - Kriterion - Journal of Philosophy 22 (1):13-31.
    Kripke presented one of the most influential modal arguments against psycho-physical identities. His argument as exemplied by the identity of pain and its respective neural correlates will be analysed in detail. It shall be argued that his reasoning relies on an implausible conception of introspection implying an implausible conception of mental phenomena such as pain. His account does not consider possible interaction of pain and attention as well as the interaction of pain with other psychological factors. Theoretical and empirical evidences (...)
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  27.  3
    Who Am I: The Conscious and the Unconscious Self.Michael Schaefer & Georg Northoff - 2017 - Frontiers in Human Neuroscience 11.
  28.  13
    First-Person Neuroscience: A New Methodological Approach for Linking Mental and Neuronal States.Georg Northoff & Alexander Heinzel - 2006 - Philosophy, Ethics, and Humanities in Medicine 1:3.
    Though the brain and its neuronal states have been investigated extensively, the neural correlates of mental states remain to be determined. Since mental states are experienced in first-person perspective and neuronal states are observed in third-person perspective, a special method must be developed for linking both states and their respective perspectives. We suggest that such method is provided by First-Person Neuroscience. What is First-Person Neuroscience? We define First-Person Neuroscience as investigation of neuronal states under guidance of and on orientation to (...)
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  29.  22
    Do Cortical Midline Variability and Low Frequency Fluctuations Mediate William James’ “Stream of Consciousness”? “Neurophenomenal Balance Hypothesis” of “Inner Time Consciousness”.Georg Northoff - 2014 - Consciousness and Cognition 30:184-200.
  30.  41
    What Catatonia Can Tell Us About “Top-Down Modulation”: A Neuropsychiatric Hypothesis.Georg Northoff - 2002 - Behavioral and Brain Sciences 25 (5):555-577.
    Differential diagnosis of motor symptoms, for example, akinesia, may be difficult in clinical neuropsychiatry. Symptoms may be either of neurologic origin, for example, Parkinson's disease, or of psychiatric origin, for example, catatonia, leading to a so-called “conflict of paradigms.” Despite their different origins, symptoms may appear more or less clinically similar. Possibility of dissociation between origin and clinical appearance may reflect functional brain organisation in general, and cortical-cortical/subcortical relations in particular. It is therefore hypothesized that similarities and differences between Parkinson's (...)
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  31.  8
    Abnormal Resting-State Connectivity in a Substantia Nigra-Related Striato-Thalamo-Cortical Network in a Large Sample of First-Episode Drug-Naïve Patients With Schizophrenia.Matteo Martino, Georg Northoff & Timothy Joseph Lane - 2017 - Schizophrenia Bulletin.
    Objective: The dopamine hypothesis is one of the most influential theories of the neurobiological background of schizophrenia (SCZ). However, direct evidence for abnormal dopamine-related subcortical-cortical circuitry disconnectivity is still lacking. The aim of this study was therefore to test dopamine-related substantia nigra (SN)-based striato-thalamo-cortical resting-state functional connectivity (FC) in SCZ. Method: Based on our a priori hypothesis, we analyzed a large sample resting-state functional magnetic resonance imaging (fMRI) dataset from first-episode drug-naïve SCZ patients (n = 112) and healthy controls (n (...)
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  32.  6
    Levels of Time in the Zhuangzi: A Leibnizian Perspective.Georg Northoff & Kai-Yuan Cheng - 2019 - Philosophy East and West 69 (4):1014-1033.
    What is time? Is time real, or a mere illusion? We seem to feel the passage of time in our consciousness but are doomed to encounter great difficulty when trying to get a deeper grip on the nature of time. As Augustine famously remarked, "if no one asks me about what time is, I know what it is, but if I wish to explain it to him who asks, I do not know". The present essay does not aim so much (...)
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  33.  92
    Are Our Emotional Feelings Relational? A Neurophilosophical Investigation of the James–Lange Theory.Georg Northoff - 2008 - Phenomenology and the Cognitive Sciences 7 (4):501-527.
    The James–Lange theory considers emotional feelings as perceptions of physiological body changes. This approach has recently resurfaced and modified in both neuroscientific and philosophical concepts of embodiment of emotional feelings. In addition to the body, the role of the environment in emotional feeling needs to be considered. I here claim that the environment has not merely an indirect and thus instrumental role on emotional feelings via the body and its sensorimotor and vegetative functions. Instead, the environment may have a direct (...)
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  34.  4
    “Paradox of Slow Frequencies” – Are Slow Frequencies in Upper Cortical Layers a Neural Predisposition of the Level/State of Consciousness ?Georg Northoff - 2017 - Consciousness and Cognition 54:20-35.
  35. How Can Searle Avoid Property Dualism? Epistemic-Ontological Inference and Autoepistemic Limitation.Georg Northoff & Kristina Musholt - 2006 - Philosophical Psychology 19 (5):589-605.
    Searle suggests biological naturalism as a solution to the mind-brain problem that escapes traditional terminology with its seductive pull towards either dualism or materialism. We reconstruct Searle's argument and demonstrate that it needs additional support to represent a position truly located between dualism and materialism. The aim of our paper is to provide such an additional argument. We introduce the concept of "autoepistemic limitation" that describes our principal inability to directly experience our own brain as a brain from the first-person (...)
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  36.  20
    Unlocking the Brain: Volume 1: Coding.Georg Northoff - 2014 - Oup Usa.
    What makes our brain a brain? This is the central question posited in Unlocking the Brain. By providing a fascinating venture into different territories of neuroscience, psychiatry, and philosophy, the author takes a novel exploration of the brain's resting state in the context of the neural code, and its ability to yield consciousness.
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  37.  18
    Unlocking the Brain: Volume 2: Consciousness.Georg Northoff - 2014 - Oup Usa.
    What makes our brain a brain? This is the central question posited in Unlocking the Brain. By providing a fascinating venture into different territories of neuroscience, psychiatry, and philosophy, the author takes a novel exploration of the brain's resting state in the context of the neural code, and its ability to yield consciousness.
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  38.  27
    How is Informed Consent Related to Emotions and Empathy? An Exploratory Neuroethical Investigation.Alexander Supady, Antonie Voelkel, Joachim Witzel, Udo Gubka & Georg Northoff - 2011 - Journal of Medical Ethics 37 (5):311-317.
    Context Informed consent is crucial in daily clinical practice and research in medicine and psychiatry. A recent neuroethical investigation explored the psychological factors that are crucial in determining whether or not subjects give consent. While cognitive functions have been shown to play a central role, the impact of empathy and emotions on subjects' decisions in informed consent remains unclear. Objective To evaluate the impact of empathy and emotions on subjects' decision in informed consent in an exploratory study. Design Decisional capacity (...)
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  39.  37
    Why Do We Need a Philosophy of the Brain?Georg Northoff - 2004 - Trends in Cognitive Sciences 8 (11):484-485.
  40. Am I My Brain? Personal Identity and Brain Identity - a Combined Philosophical and Psychological Investigation in Brain Implants.Georg Northoff - 2004 - Philosophia Naturalis 41 (2):257-282.
     
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  41.  83
    Is Appraisal 'Embodied' and 'Embedded'? A Neurophilosophical Investigation of Emotions.Georg Northoff - 2008 - Journal of Consciousness Studies 15 (5):68-99.
    Emotion theories in present philosophical discussion propose different models of relationship between feeling and appraisal. The multicomponent model considers appraisal as separate component and distinguishes it from feeling and physiological body changes thus presupposing what may be called 'disembodied' and 'disembedded' appraisal as representational. The recently emerged concept of enactment, in contrast, argues that appraisal is closely linked to feeling and physiological body changes presupposing what can be called 'embodied' and 'embedded' appraisal as relational. The aim of the paper is (...)
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  42.  8
    Lessons From Astronomy and Biology for the Mind—Copernican Revolution in Neuroscience.Georg Northoff - 2019 - Frontiers in Human Neuroscience 13.
  43. Emotional Feeling and the Orbitomedial Prefrontal Cortex: Theoretical and Empirical Considerations.Georg Northoff & Alexander Heinzel - 2009 - Philosophical Psychology 22 (4):443-464.
    Emotional feeling can be defined as the affective constituent of emotions representing a subjective experience such as, for example, feeling love or hate. Several recent neuroimaging studies have focused on this affective component of emotions thereby aiming to characterise the underlying neural correlates. These studies indicate that the orbitomedial prefrontal cortex is crucially involved in the processing of emotional feeling. It is the aim of this paper to analyse the extent to which the present state of the art in neuroscience (...)
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  44.  90
    What is Neurophilosophy? A Methodological Account.Georg Northoff - 2004 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 35 (1):91-127.
    The term ``neurophilosophy'' is often used either implicitly or explicitly for characterizing the investigation of philosophical theories in relation to neuroscientific hypotheses. The exact methodological principles and systematic rules for a linkage between philosophical theories and neuroscientific hypothesis, however, remain to be clarified. The present contribution focuses on these principles, as well as on the relation between ontology and epistemology and the characterization of hypothesis in neurophilosophy. Principles of transdisciplinary methodology include the `principle of asymmetry', the `principle of bi-directionality' and (...)
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  45.  16
    Qualia and the Ventral Prefrontal Cortical Function 'Neurophenomenological' Hypothesis.Georg Northoff - 2003 - Journal of Consciousness Studies 10 (8):14-48.
    The exact relationship between qualia and the function of the brain remains elusive. The present approach focuses on the linkage between the neural mechanisms of the brain and the phenomenological and epistemological mechanisms of qualia. It is hypothesized that distinct characteristics of the ventral prefrontal cortical function may be crucial for the generation of these phenomenological and epistemological mechanisms this is reflected in the so-called 'neurophenomenological hypothesis'. The 'phenomenological—qualitative' character of qualia may be related with an early activation in the (...)
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  46.  37
    What Are the Subjective Processes in Our Brain? Empirical and Ethical Implications of a Relational Concept of the Brain.Georg Northoff - 2009 - American Journal of Bioethics 9 (9):27-28.
  47.  42
    Qualia Im Knotenpunkt Zwischen Leib Und Seele: „Argumentatives“ Dilemma in der Gegenwärtigen Diskussion Über Die Subjektivität Mentaler Zustände. [REVIEW]Georg Northoff - 1995 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 26 (2):269 - 295.
    Qualia in the node-point between mind and body: Dilemma of present discussion about the subjectivity of mental states. The present discussion about qualia shows a bewildering variety of different positions. We show implicit assumptions about brain, subject, and qualia of this complex discussion. By means of three assumptions we divide the discussion about qualia into three different positions (proposition, opposition, intermediate solutions). These positions and their exemplaric authors are briefly presented along the lines of the three assumptions. The next step (...)
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  48.  51
    Are "Q-Memories" Empirically Realistic? A Neurophilosophical Approach.Georg Northoff - 2000 - Philosophical Psychology 13 (2):191-211.
    "Quasi-memories," necessarily presupposing a distinction between an "experiencing" and a "remembering" person, are considered by Parfit and Shoemaker as necessary and/or sufficient criteria for personal identity. However, the concept of "q-memories" is rejected by Schechtman since, according to her, neither "content" and "experience" can be separated from each other in "q-memories" ("principal inseparability") nor can they be distinguished from delusions/confabulations ("principal indistinguishability"). The purpose of the present paper is to demonstrate that, relying on a neurophilosophical approach, both arguments can be (...)
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  49.  16
    What Neuroscience and Neurophilosophy Can Tell Us About the Effects of Deep Brain Stimulation on the Self.Georg Northoff - 2017 - American Journal of Bioethics Neuroscience 8 (2):55-58.
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  50.  79
    "Brain-Paradox" and "Embeddment": Do We Need a "Philosophy of the Brain"?Georg Northoff - 2001 - Brain and Mind 195 (2):195-211.
    Present discussions in philosophy of mind focuson ontological and epistemic characteristics ofmind and on mind-brain relations. In contrast,ontological and epistemic characteristics ofthe brain have rarely been thematized. Rather,philosophy seems to rely upon an implicitdefinition of the brain as "neuronal object''and "object of recognition'': henceontologically and epistemically distinct fromthe mind, characterized as "mental subject'' and"subject of recognition''. This leads to the"brain-paradox''. This ontological and epistemicdissociation between brain and mind can beconsidered central for the problems of mind andmind-brain relations that have yet (...)
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