The term research subject has traditionally been the preferred term in professional guidelines and academic literature to describe a patient or an individual taking part in biomedical research. In recent years, however, there has been a steady shift away from the use of the term 'research subject' in favour of 'research participant' when referring to individuals who take part by providing data to various kinds of biomedical and epidemiological research. This article critically examines this shift, reflecting on the different meanings (...) evoked by the terms 'subject' and 'participant', as well as examining recent examples of patient activism in research. It concludes by suggesting that the wholesale unreflective adoption of the term 'participant' is inappropriate and provides instead a guide on how to determine the circumstances in which the terms subject, participant and activist should legitimately be used. (shrink)

This article argues that Ralph Waldo Emerson employs metempsychosis (reincarnation or the transmigration of the soul into successive bodies) as a figurative template for human consciousness. Mapping various traditions from Hinduism, Pythagoreanism, Platonism, and Neoplatonism onto the vastness of the geological and biological records, Emerson translates metaphysics for modernity: he depicts the soul's journey through the chronological sequence of history as a poetic process that culminates in a tenuous form of self-knowledge.

Concern about the ethics of clinical drug trials research on patients and healthy volunteers has been the subject of significant ethical analysis and policy development—protocols are reviewed by Research Ethics Committees and subjects are protected by informed consent procedures. More recently attention has begun to be focused on DNA banking for clinical and pharmacogenetics research. It is, however, surprising how little attention has been paid to the commercial nature of such research, or the unique issues that present when subjects are (...) asked to consent to the storage of biological samples. Our contention is that in the context of pharmacogenetic add-on studies to clinical drug trials, the doctrine of informed consent fails to cover the broader range of social and ethical issues. Applying a sociological perspective, we foreground issues of patient/subject participation or ‘work’, the ambiguity of research subject altruism, and the divided loyalties facing many physicians conducting clinical research. By demonstrating the complexity of patient and physician involvement in clinical drug trials, we argue for more comprehensive ethical review and oversight that moves beyond reliance on informed consent to incorporate understandings of the social, political and cultural elements that underpin the diversity of ethical issues arising in the research context. (shrink)

This book explores the intimate connections, conflicts and discontinuities between religion and philosophy in the Platonic and Neoplatonic traditions from Antiquity to the early Medieval period. It presents a broader comparative view of Platonism by examining the strong Platonist resonances among different philosophical/religious traditions, primarily Jewish, Christian, Islamic and Hindu, and suggests many new ways of thinking about the relation between these two fields or disciplines that have in modern times become such distinct and, at times, entirely separate domains.

A review of the literature indicates that linear models are frequently used in situations in which decisions are made on the basis of multiple codable inputs. These models are sometimes used normatively to aid the decision maker, as a contrast with the decision maker in the clinical vs statistical controversy, to represent the decision maker "paramorphically" and to "bootstrap" the decision maker by replacing him with his representation. Examination of the contexts in which linear models have been successfully employed indicates (...) that the contexts have the following structural characteristics in common: each input variable has a conditionally monotone relationship with the output; there is error of measurement; and deviations from optimal weighting do not make much practical difference. These characteristics ensure the success of linear models, which are so appropriate in such contexts that random linear models may perform quite well. 4 examples involving the prediction of such codable output variables as GPA and psychiatric diagnosis are analyzed in detail. In all 4 examples, random linear models yield predictions that are superior to those of human judges. (shrink)

This paper investigates the effects of relative position and proxemics in the engagement process involved in Human-Robot collaboration. We evaluate the differences between two experimental placement conditions for an autonomous robot in a collaborative task with a user across two different types of robot behaviours. The study evaluated placement and behaviour types around a touch table with 80 participants by measuring gaze, smiling behaviour, distance from the task, and finally electrodermal activity. Results suggest an overall user preference and higher engagement (...) rates with the helpful robot in the frontal position. We discuss how behaviours and position of the robot relative to a user may affect user engagement and collaboration, in particular when the robot aims to provide help via socio-emotional bonding. (shrink)

In September this year the Nuffield Council on Bioethics held a meeting to disclose and discuss the main findings of their newly published report on the ethical issues associated with developments in pharmacogenetics research. The basics of pharmacogenetics science is briefly outlined, and then the extent to which the report was successful in addressing the attendant social, ethical, and policy implications of pharmacogenetics research is evaluated.

This paper investigates the effects of relative position and proxemics in the engagement process involved in Human-Robot collaboration. We evaluate the differences between two experimental placement conditions for an autonomous robot in a collaborative task with a user across two different types of robot behaviours. The study evaluated placement and behaviour types around a touch table with 80 participants by measuring gaze, smiling behaviour, distance from the task, and finally electrodermal activity. Results suggest an overall user preference and higher engagement (...) rates with the helpful robot in the frontal position. We discuss how behaviours and position of the robot relative to a user may affect user engagement and collaboration, in particular when the robot aims to provide help via socio-emotional bonding. (shrink)

This book tells a compelling story about love, friendship, and the Divine that took over a thousand years to unfold. It argues that mind and feeling are intrinsically connected in the thought of Plato, Aristotle, and Plotinus; that Aristotle developed his theology and physics primarily from Plato’s Symposium (from the “Greater” and “Lesser Mysteries” of Diotima-Socrates’ speech); and that the Beautiful and the Good are not coincident classes, but irreducible Forms, and the loving ascent of the Symposium must be interpreted (...) in the light of the Republic, as the later tradition up to Ficino saw. Against the view that Platonism is an escape from the ambiguities of ordinary experience or opposed to loving individuals for their own sakes, this book argues that Plato dramatizes the ambiguities of ordinary experience, confronts the possibility of failure, and bequeaths erotic models for the loving of individuals to later thought. Finally, it examines the Platonic-Aristotelian heritage on the Divine to discover whether God can love us back, and situates the dramatic development of this legacy in Plotinus, Iamblichus, Proclus, and Dionysius the Areopagite. (shrink)

Part I. Gnosticism and other religious movements of antiquity -- part II. Crossing boundaries : Gnosticism and Platonism.

v. 1. From Plato and the old academy to middle platonism -- v. 2. Middle platonic and gnostic texts.

Simmias' famous epiphenomenalist analogy of the soul-body relation to the harmony and strings of a lyre leads to Socrates' initial refutation and subsequent prolonged defense of soul's immortality in the Phaedo. It also yields in late antiquity significant treatments of the harmony relation by Plotinus and Porphyry that present a larger context for viewing the nature of harmony in the soul and the psycho-somatic compound. But perhaps the most detailed treatment of the musical analogy, and certainly the most radical, is (...) to be found in Gregory of Nyssa's De Hominis Opificio. Gregory's remarkable development of the musical instrument analogy provides a multi-layered analysis of interrelated causality on the mechanistic, physiological, psycho-somatic and intellectual/spiritual planes. Gregory not only sees mind/soul and body as radically equal and yet multilayered in their mutual development; he also refuses to restrict mind to the brain alone, for all physiological systems, in his view, are holistically and individually expressive of mind's activity. Gregory's theory is more innovative than Augustine's view of the mind/soul-body relation and, in my view, the most important account between Plotinus and Aquinas. (shrink)

The contributors to this volume offer, in the light of specialised knowledge of leading philosophers of the ancient world, answers to the question: how are we to read and understand the surviving texts of Parmenides, Plato, Aristotle, Plotinus and Augustine?

The contributors to this volume offer, in the light of specialised knowledge of leading philosophers of the ancient world, answers to the question: how are we to read and understand the surviving texts of Parmenides, Plato, Aristotle, Plotinus and Augustine?

This volume collects essays under four categories: religious traditions, religious life, emotional states, and historical and theoretical perspectives. These essays describe the ways in which emotions have played a role in various world religions, and analyze the manner in which key components of religious life ritual, music, gender, sexuality and material culture represent and shape emotional performance.

Concern about the ethics of clinical drug trials research on patients and healthy volunteers has been the subject of significant ethical analysis and policy development—protocols are reviewed by Research Ethics Committees and subjects are protected by informed consent procedures. More recently attention has begun to be focused on DNA banking for clinical and pharmacogenetics research. It is, however, surprising how little attention has been paid to the commercial nature of such research, or the unique issues that present when subjects are (...) asked to consent to the storage of biological samples. Our contention is that in the context of pharmacogenetic add-on studies to clinical drug trials, the doctrine of informed consent fails to cover the broader range of social and ethical issues. Applying a sociological perspective, we foreground issues of patient/subject participation or ‘work’, the ambiguity of research subject altruism, and the divided loyalties facing many physicians conducting clinical research. By demonstrating the complexity of patient and physician involvement in clinical drug trials, we argue for more comprehensive ethical review and oversight that moves beyond reliance on informed consent to incorporate understandings of the social, political and cultural elements that underpin the diversity of ethical issues arising in the research context. (shrink)

Rights of nature is an idea that has come of age. In recent years, a diverse range of countries and jurisdictions have adopted these norms, which involve granting legal rights to nature or natural objects, such as rivers, forests, or ecosystems. This book critically examines the idea of natural objects as right-holders, and analyses legal cases, policies, and philosophical issues relating to this development. -/- Drawing on contributions from a range of experts in the field, Rights of Nature: A Re-examination (...) investigates the potential for this innovative idea to revolutionize the concepts of rights, standing, and recognition as traditionally understood in many legal systems. Taking as its starting point Stone’s influential 1972 article ‘Should Trees Have Standing?’, the book examines the progress rights of nature have made since that time, by identifying central themes, unifying principles, and key distinctions in how rights of nature discourse has been operationalized in the disciplines of law, philosophy, and the social sciences. These themes and principles are illustrated through a wide variety of examples, including ecosystem services, indigenous thinking, and ecological restoration, demonstrating how the relationship between humanity and the natural world may be transforming. -/- Taking a philosophical, political, and legal perspective, this book will be of great interest to students and scholars of environmental law and policy, environmental ethics, and philosophy. (shrink)

This book makes accessible, to a wide audience, the thought of Evagrius and Gregory on the soul, in the context of ancient philosophy/theology and the Cappadocians generally. Corrigan argues that in these two figures we witness the birth of new forms of thought and of empirical science in a new key. Evagrius and Gregory are no mere receivers of a monolithic pagan and Christian tradition, but innovative, critical interpreters on the range and limits of cognitive psychology, the soul-body relation, (...) reflexive self-knowledge, personal and human identity and the soul's practical relation to goodness in the context of human experience and divine self-disclosure. This book provides a critical evaluation of their thought on these major issues and argues that in Evagrius and Gregory we see the important integration of many different concerns that later Christian thought was not always able to balance including: mysticism, asceticism, cognitive science, philosophy, and theology. (shrink)

This open access book tackles the pressing problem of integrating concerns related to Artificial Intelligence (AI) ethics into higher education curriculums aimed at future AI developers in Africa and beyond. For doing so, it analyzes the present and future states of AI ethics education in local computer science and engineering programs. The authors share relevant best practices and use cases for teaching, develop answers to ongoing organizational challenges, and reflect on the practical implications of different theoretical approaches to AI ethics. (...) The book is of great interest to faculty members, researchers, and students in the fields of artificial intelligence, computer science, mathematics, computer engineering, and related areas, as well as higher education administration. (shrink)

More collaborative work in the humanities could be instrumental in helping to break down the traditional rigid boundaries between academic divisions and disciplines in modern universities. The value of the traditional model of the solitary humanities scholar or the collaborative science paradigm should not be discounted. However, increasing the use of collaborative and interdisciplinary research models in the humanities would promote new forms of scholarship and also help to create a better, more integral and inclusive world.

Este artículo trabaja la presencia plotiniana en la Edad Media y el Renacimiento. En primer término, se presenta el movimiento de transmisión indirecta de las Enéadas a lo largo de la Edad Media y las ediciones que resurgen en el Renacimiento. En esta línea, se discute precisamente la presencia e influencia de las ideas plotinianas en pensadores medievales. En segundo término, se despliegan ciertas notas nucleares del pensamiento de Plotino –las tres hipóstasis y un solo universo– para luego, en tercer (...) término, exponer las profundas coincidencias que pueden encontrarse en la estructura del pensamiento de Nicolás de Cusa –con el estudio del lenguaje de los binomios complicación-explicación, incontracto-contracto. Finalmente, se considera la posibilidad de incluir a ambos autores en una Gran Teoría Unificada que se despliega a lo largo de la Edad Media. (shrink)