Researchers have iterated that the future of synthetic biology and biotechnology lies in novel consumer applications of crossing biology with engineering. However, if the new biology’s future is to be sustainable, early and serious efforts must be made towards social sustainability. Therefore, the crux of new applications of synthetic biology and biotechnology is public understanding and acceptance. The RASVaccine is a novel recombinant design not found in nature that re-engineers a common bacteria to produce a strong immune response in humans. (...) Synthesis of the RASVaccine has the potential to improve public health as an inexpensive, non-injectable product. But how can scientists move forward to create a dialogue of creating a ‘common sense’ of this new technology in order to promote social sustainability? This paper delves into public issues raised around these novel technologies and uses the RASVaccine as an example of meeting the public with a common sense of its possibilities and limitations. (shrink)

Researchers have iterated that the future of synthetic biology and biotechnology lies in novel consumer applications of crossing biology with engineering. However, if the new biology’s future is to be sustainable, early and serious efforts must be made towards social sustainability. Therefore, the crux of new applications of synthetic biology and biotechnology is public understanding and acceptance. The RASVaccine is a novel recombinant design not found in nature that re-engineers a common bacteria to produce a strong immune response in humans. (...) Synthesis of the RASVaccine has the potential to improve public health as an inexpensive, non-injectable product. But how can scientists move forward to create a dialogue of creating a ‘common sense’ of this new technology in order to promote social sustainability? This paper delves into public issues raised around these novel technologies and uses the RASVaccine as an example of meeting the public with a common sense of its possibilities and limitations. (shrink)

Initially commissioned to record the progress of Pittsburgh’s Renaissance I, these unforgettable black-and-white photographs of Roy Stryker's Pittsburgh Photographic Library capture the city in a state of flux. They reveal a union of opposites—the suited wonderment of the downtown businessman with the easy grace and competence of a shirtless construction worker balanced high over his head; the anonymity and isolation of planned housing with the belief in expansion and renewal; the energy and excitement of a city on the move with (...) the traditions of the established elite; the juxtaposition between the growing optimism about the ability of technology to improve our lives; and the traditional steel and other heavy smokestack industries that still dominated the region. The Renaissance was seen as a way for Pittsburgh to keep abreast of modern urban life and to preserve its economic position, but the rapid development of a white suburban middle class was sapping the very essence of the personalized downtown neighborhoods. These photographers have captured the convergence of destruction and rejuvenation that is the essence of an urban renaissance—all the anxiety and hope of the decade is reflected in these poignant photographs. Constance Schulz's fascinating essay on the story of the PPL, in order to present a full picture of the political and civic goals, achievements, and failings of the project, provides a thorough discussion of the background of the Pittsburgh Photographic Library, putting into perspective the Allegheny Conference's purpose for initiating the PPL, Roy Stryker's own vision and work, as well as those of the photographers who worked for Stryker on the project, and the politics that undermined the full implementation of it. Clark M. Thomas's accompanying narrative offers an eclectic range of facts and fascinating bits of the city's history and neighborhood lore, as well as noting important political and economic episodes. It also provides a glimpse into the often underrepresented lives of minorities and women in the region's development. Anyone moved by the incredible social upheaval and expansion that occurred in cities across the nation in the 1950s following years of depression and war will want to have this collection. (shrink)

The Enlightenment has often been written about as a sequence of disembodied 'great ideas'. The aim of this book is to put the beliefs of the Enlightenment firmly into their social context, by revealing the national soils in which they were rooted and the specific purposes for which they were used. It brings out the regional divergences of the Enlightenment experience, shaped by different local intellectual and economic priorities. At the same time it also shows how central concerns were shared (...) everywhere, and how the writings of certain key areas came to be influential elsewhere. The thirteen essays, each written by a historian specialising in the particular country, examine national contexts from Sweden to Italy, from Russia to North America. As well as focusing attention on the interplay of thought and action, ideology and society, the book offers important insights into the place of the intelligentsia in the modern world. (shrink)

Labioplasty is a surgical procedure performed to alter the size and shape of the labia minora. The reasons for women requesting this procedure remain largely unknown and recently girls and young women under the age of 18 years have been requesting this type of surgery. This paper examines the ethical acceptability of performing this procedure on under 18s. We will first discuss whether labioplasty can be considered to be a therapeutic technique. We will claim that, while it is difficult to (...) offer a definitive definition of what constitutes a therapeutic technique, in our view labioplasty cannot be considered as such. This conclusion has relevance for the ethical acceptability of the procedure, its legal status in regard to the Female Genital Mutilation Act and the debates over who can give consent for it. It will be concluded that in our current state of knowledge, the benefits of labioplasty are far from clear, whereas the harms are demonstrable and therefore this procedure should not be offered to those aged under 18 years. (shrink)

This dissertation examines Sigmund Freud's psychoanalysis with particular regard to the problem of nihilism, and the philosophy of history that Edmund Husserl and Georg Lukacs argue is needed in its wake to restore reason's capacity to give order and direction to human life. I understand nihilism not merely as the theory that life is devoid of value, but rather as an historical crisis in the sense of autonomy that results from the separation of fact and value in the thoroughly rationalized (...) modern world. How, I ask, does Freud respond to this crisis? And how does his response stand in relationship to those offered by philosophers? Does psychoanalysis too provide a philosophy of history? ;To answer these questions, I first examine the development of psychoanalysis in response to the suffering of neurotics as a crisis in the authority of science to address human needs. I then explicate the problem of nihilism as it is registered by both Husserl and Lukacs, examine the philosophies of history that they each construct in response to it, and consider Freud's theory of civilization in relationship to them. ;By constructing philosophical methodologies to defend reason's teleology, I argue that both Husserl and Lukacs implicitly disavow the problem that they purport to address by presupposing the autonomy of reason, and treating the problem of nihilism as the result merely of a misconception concerning its place and function in the world. As late as 1923 Freud too presupposes reason's autonomy from the terror expressed in religion. However, with his subsequent recognition of the problem presented by the unconscious sense of guilt, Freud no longer treats the rational overcoming of illusion as an intrinsic good. He sees civilization too as radically ambivalent and revises his social theory as a critique of the discontent that immanently plagues it. Rather than a philosophy of history, I argue that Freud constructs a critique of the problem presented by the persistent demand for teleological orientation in a post-historical world. (shrink)

It is demonstrated that a non Abelian Stokes Theorem is necessary to describe the B3 field of radiation. A simple form of the theorem is build up from the fundamental definition of B3 in O(3) gauge field theory, which is a gauge field theory applied to electrodynamics with an O(3) internal gauge symmetry bases on a complex basis ((1), (2), (3)). The indices (1) and (2) are complex conjugate pairs based on circular polarization, and the index (3) is aligned with (...) the propagation axis of radiation. (shrink)

A substantial portion of the developed world's population is increasingly dependent on machines to make their way in the everyday world. For certain privileged groups, computers, cell phones, PDAs, Blackberries, and IPODs, all permitting the faster processing of information, are commonplace. In these populations, even exercise can be automated as persons try to achieve good physical fitness by riding stationary bikes, running on treadmills, and working out on cross-trainers that send information about performance and heart rate.

Emotional intelligence abilities relate to desirable outcomes such as better well-being, academic performance, and job performance. Previous research shows that coping strategies mediate the effects of ability EI on such outcomes. Across two cross-sectional studies, we show that coping strategies mediate the relationships of ability EI with both well-being and ill-being. Study 1 assessed EI with the Situational Test of Emotion Understanding and Situation Test of Emotion Management. Avoidant coping significantly mediated the relationship of both the STEU and STEM with (...) depression, anxiety, stress, and psychological well-being. EI was associated with lower avoidant coping, higher well-being and lower ill-being. Study 2 assessed EI with the Mayer–Salovey–Caruso Emotional Intelligence Test. Avoidant coping mediated the relationship between EI and ill-being, but not the relationship between EI and well-being. These effects were significant for three of the four EI branches—emotion perception, understanding, and management. We discuss possible reasons why avoidant coping may be an active ingredient by which lower EI relates to lower well-being. We also discuss a possible application of our findings—that EI training programs might benefit from including content aimed at reducing avoidant coping. (shrink)

Abstract:In this forum, Marilyn Strathern and Jade S. Sasser review Adele Clarke and Donna Haraway's edited volume Making Kin, Not Population: Reconceiving Generations (Prickly Paradigm Press, 2018). Responses from multiple authors featured in the book follow.

Mechanical devices implanted in the body present implications for broad themes in religious thought and experience, including the nature and destiny of the human person, the significance of a person's embodied experience, including the experiences of pain and suffering, the person's relationship to ultimate reality, the divine or the sacred, and the vocation of medicine. Community-constituting convictions and narratives inform the method and content of reasoning about such conceptual questions as whether a moral line should be drawn between therapeutic or (...) enhancement interventions and/or between somatic and neural/cognitive interventions. By attending to these broader community-forming concepts, it is possible to identify three general orienting themes in religious perspectives on incorporated mechanical devices, which we shall designate as perspectives of “appropriation,” “ambivalence,” and “resistance.”. (shrink)

Jerry Fodor deemed informational encapsulation ‘the essence’ of a system’s modularity and argued that human perceptual processing comprises modular systems, thus construed. Nowadays, his conclusion is widely challenged. Often, this is because experimental work is seen to somehow demonstrate the cognitive penetrability of perceptual processing, where this is assumed to conflict with the informational encapsulation of perceptual systems. Here, I deny the conflict, proposing that cognitive penetration need not have any straightforward bearing on the conjecture that perceptual processing is composed (...) of nothing but informationally encapsulated modules, the conjecture that each and every perceptual computation is performed by an informationally encapsulated module, and the consequences perceptual encapsulation was traditionally expected to have for a perception-cognition border, the epistemology of perception and cognitive science. With these points in view, I propose that particularly plausible cases of cognitive penetration would actually seem to evince the encapsulation of perceptual systems rather than refute/problematize this conjecture. (shrink)

This paper argues for two theses: that degrees of belief are context sensitive; that outright belief is belief to degree 1. The latter thesis is rejected quickly in most discussions of the relationship between credence and belief, but the former thesis undermines the usual reasons for doing so. Furthermore, identifying belief with credence 1 allows nice solutions to a number of problems for the most widely-held view of the relationship between credence and belief, the threshold view. I provide a sketch (...) of a formal framework on which both theses are true. This is a modified Bayesian framework; I argue that despite making credences context-sensitive, the framework lets Bayesians hold on to their signature explanatory successes. The sort of context-sensitivity claimed for credences here mirrors the sort of context-sensitivity I have elsewhere claimed for outright belief: one's credences depend, in part, on the space of alternative possibilities one takes seriously in a context. (shrink)

Modal Security is an increasingly discussed proposed necessary condition on undermining defeat. Modal Security says, roughly, that if evidence undermines (rather than rebuts) one’s belief, then one gets reason to doubt the belief's safety or sensitivity. The primary interest of the principle is that it seems to entail that influential epistemological arguments, including Evolutionary Debunking Arguments against moral realism and the Benacerraf-Field Challenge for mathematical realism, are unsound. The purpose of this paper is to critically examine Modal Security in detail. (...) We develop and discuss what we take to be the strongest objections to the principle. One of the aims of the paper is to expose the weakness of these objections. Another is to reveal how the debate over Modal Security interacts with core problems in epistemology — including the generality problem, and the distinction between direct and indirect evidence. (shrink)

It is often claimed that pre-attentive vision has an ‘iconic’ format. This is seen to explain pre-attentive vision's characteristically high processing capacity and to make sense of an overlap in the mechanisms of early vision and mental imagery. But what does the iconicity of pre-attentive vision amount to? This paper considers two prominent ways of characterising pre-attentive visual icons and argues that neither is adequate: one approach renders the claim ‘pre-attentive vision is iconic’ empirically false while the other obscures its (...) ability to do the explanatory work, which motivates positing pre-attentive visual icons in the first place. With this noted, I introduce the notion of an ‘Analogue Map’ and argue that it provides a superior characterisation of pre-attentive vision's iconicity. I then argue that this forces a reassessment of debates which have traditionally presupposed the iconicity of pre-attentive vision, emphasising ramifications for the viability of a format-based perception-thought border. (shrink)

In his influential book, The Nature of Morality, Gilbert Harman writes: “In explaining the observations that support a physical theory, scientists typically appeal to mathematical principles. On the other hand, one never seems to need to appeal in this way to moral principles.” What is the epistemological relevance of this contrast, if genuine? This chapter argues that ethicists and philosophers of mathematics have misunderstood it. They have confused what the chapter calls the justificatory challenge for realism about an area, D—the (...) challenge to justify our D-beliefs—with the reliability challenge for D-realism—the challenge to explain the reliability of our D-beliefs. Harman’s contrast is relevant to the first, but not, evidently, to the second. One upshot of the discussion is that genealogical debunking arguments are fallacious. Another is that indispensability considerations cannot answer the Benacerraf–Field challenge for mathematical realism. (shrink)

This book discusses the problem of mathematical knowledge, and its broader philosophical ramifications. It argues that the problem of explaining the (defeasible) justification of our mathematical beliefs (‘the justificatory challenge’), arises insofar as disagreement over axioms bottoms out in disagreement over intuitions. And it argues that the problem of explaining their reliability (‘the reliability challenge’), arises to the extent that we could have easily had different beliefs. The book shows that mathematical facts are not, in general, empirically accessible, contra Quine, (...) and that they cannot be dispensed with, contra Field. However, it argues that they might be so plentiful that our knowledge of them is intelligible. The book concludes with a complementary ‘pluralism’ about modality, logic and normative theory, highlighting its revisionary implications. Metaphysically, pluralism engenders a kind of perspectivalism and indeterminacy. Methodologically, it vindicates Carnap’s pragmatism, transposed to the key of realism. (shrink)

In this defense of Reliabilism, I argue that there has been 'selection for' accurate indexical beliefs. I offer empirical evidence and examples to suggest that Steve Stich's defense of the opposite claim in The Fragmentation of Reason is misguided.

Set-theoretic pluralism is an increasingly influential position in the philosophy of set theory (Balaguer [1998], Linksy and Zalta [1995], Hamkins [2012]). There is considerable room for debate about how best to formulate set-theoretic pluralism, and even about whether the view is coherent. But there is widespread agreement as to what there is to recommend the view (given that it can be formulated coherently). Unlike set-theoretic universalism, set-theoretic pluralism affords an answer to Benacerraf’s epistemological challenge. The purpose of this paper is (...) to determine what Benacerraf’s challenge could be such that this view is warranted. I argue that it could not be any of the challenges with which it has been traditionally identified by its advocates, like of Benacerraf and Field. Not only are none of the challenges easier for the pluralist to meet. None satisfies a key constraint that has been placed on Benacerraf’s challenge. However, I argue that Benacerraf’s challenge could be the challenge to show that our set-theoretic beliefs are safe – i.e., to show that we could not have easily had false ones. Whether the pluralist is, in fact, better positioned to show that our set-theoretic beliefs are safe turns on a broadly empirical conjecture which is outstanding. If this conjecture proves to be false, then it is unclear what the epistemological argument for set-theoretic pluralism is supposed to be. (shrink)

Sometimes someone does something morally wrong in clear-eyed awareness that what she is doing is wrong. More commonly, a wrongdoer fails to see that her conduct is wrong. Call the latter behavior unwitting wrongful conduct. It is generally agreed that an agent can be blameworthy for such conduct, but there is considerable disagreement about how one’s blameworthiness in such cases is to be explained, or what conditions must be satisfied for the agent to be blameworthy for her conduct. Many theorists (...) hold that an agent’s blameworthiness for unwitting wrongful conduct must stem from—or trace back to—her blameworthiness for something else. And appeals to tracing in these cases lead some writers to a highly revisionist view, on which people are blameworthy for wrongdoing much less often than we ordinarily think (and our mistake, unfortunately, isn’t about how much wrongdoing there is). In this chapter, I set out the main claims of an argument for such a view and respond to it. I offer grounds for retaining a good many of the judgments that the revisionist would have us reject. The defense rests to a significant extent on commonsense views about the psychological capacities and abilities to act that people ordinarily possess, views that, as far as I can tell, revisionists have not shown to be mistaken. (shrink)

Economic models are founded in the idea of taking individuals' preferences as both known and given. This article explores the evolution of personal preferences, within a context of both entrepreneurial discovery and Objectivist philosophy. It begins by formalizing Ayn Rand's theory of Objectivism applied to human values, and continues by modeling preference changes similar to Schumpeter's theory of creative destruction—a process of self-discovery. Next the role of societal factors is examined in forming shared preference sets. Finally, the article describes how (...) the strength of human preferences is used to narrow choice sets in the presence of greater consumption options. (shrink)

It is commonly suggested that evolutionary considerations generate an epistemological challenge for moral realism. At first approximation, the challenge for the moral realist is to explain our having many true moral beliefs, given that those beliefs are the products of evolutionary forces that would be indifferent to the moral truth. An important question surrounding this challenge is the extent to which it generalizes. In particular, it is of interest whether the Evolutionary Challenge for moral realism is equally a challenge for (...) mathematical realism. It is widely thought not to be. In this paper, I argue that the Evolutionary Challenge for moral realism is equally a challenge for mathematical realism. Along the way, I substantially clarify the Evolutionary Challenge, discuss its relation to more familiar epistemological challenges, and broach the problem of moral disagreement. The paper should be of interest to ethicists because it places pressure on anyone who rejects moral realism on the basis of the Evolutionary Challenge to reject mathematical realism as well. And the paper should be of interest to philosophers of mathematics because it presents a new epistemological challenge for mathematical realism that bears, I argue, no simple relation to Paul Benacerraf's familiar challenge. (shrink)

Darwin’s classic ‘Origin of Species’ (Darwin 1859) described forces of selection acting upon individuals, but there remains a great deal of controversy about what exactly the status and definition of a biological individual is. Recently some authors have argued that the individual is dispensable – that an inability to pin it down is not problematic because little rests on it anyway. The aim of this paper is to show that there is a real problem of biological individuality, and an urgent (...) need to arbitrate over the current plethora of solutions to it. (shrink)

Should economics study the psychological basis of agents' choice behaviour? I show how this question is multifaceted and profoundly ambiguous. There is no sharp distinction between "mentalist'' answers to this question and rival "behavioural'' answers. What's more, clarifying this point raises problems for mentalists of the "functionalist'' variety (Dietrich and List, 2016). Firstly, functionalist hypotheses collapse into hypotheses about input--output dispositions, I show, unless one places some unwelcome restrictions on what counts as a cognitive variable. Secondly, functionalist hypotheses make some (...) risky commitments about the plasticity of agents' choice dispositions. (shrink)

Many philosophical theories of causation are egalitarian, rejecting a distinction between causes and mere causal conditions. We sought to determine the extent to which people's causal judgments discriminate, selecting as causes counternormal events—those that violate norms of some kind—while rejecting non-violators. We found significant selectivity of this sort. Moreover, priming that encouraged more egalitarian judgments had little effect on subjects. We also found that omissions are as likely as actions to be judged as causes, and that counternormative selectivity appears to (...) apply equally to actions and omissions. (shrink)

In this article, we discuss a simple argument that modal metaphysics is misconceived, and responses to it. Unlike Quine's, this argument begins with the simple observation that there are different candidate interpretations of the predicate ‘could have been the case’. This is analogous to the observation that there are different candidate interpretations of the predicate ‘is a member of’. The argument then infers that the search for metaphysical necessities is misguided in much the way the ‘set-theoretic pluralist’ claims that the (...) search for the true axioms of set theory is. We show that the obvious responses to this argument fail. However, a new response has emerged that purports to prove, from higher-order logical principles, that metaphysical possibility is the broadest kind of possibility applying to propositions, and is to that extent special. We distill two lines of reasoning from the literature, and argue that their import depends on premises that any ‘modal pluralist’ should deny. Both presuppose that there is a unique typed hierarchy, which is what the modal pluralist, in the context of higher-order logic, should disavow. In other words, both presupposes that there is a unique candidate for what higher-order claims could mean. We consider the worry that, in a higher-order setting, modal pluralism faces an insuperable problem of articulation, collapses into modal monism, is vulnerable to the Russell-Myhill paradox, or even contravenes the truism that there is a unique actual world, and argue that these worries are misplaced. We also sketch the bearing of the resulting ‘Higher-Order Pluralism’ on the theory of content. One theme of the discussion is that, if Higher-Order Pluralism is correct, then there is no fixed metatheory from which to characterize higher-order reality. (shrink)

Viewing animals as a disposable resource is by no means novel, but does milking the cow for all its worth now represent a previously unimaginable level of exploitation? New technology has intensified milk production fourfold over the last 50 years, rendering the cow vulnerable to various and frequent clinical interventions deemed necessary to meet the demands for dairy products. A major question is whether or not the veterinary code of practice fits, or is in ethical tension, with the administration of (...) ‘efficient’ techniques, such as artificial insemination, to enhance reproduction levels among cattle? Vets perform these interventions and their ‘success’ is measured by the maximisation of milk production, requiring perpetually pregnant cows. Our empirical research on 33 farm vets explores how their professional ethical code promising to protect the welfare of the animal ‘above all else’, is increasingly in conflict with, and subordinate to, the financial demands of clients. Since vets cannot stand outside of the productive power–knowledge relations that have intensified the consumption of animal bodily parts and secretions, we argue that a process of adiaphorization’ occurs, whereby humans become morally indifferent to cruel practices deemed necessary to our consumerist ways of life. However, this indifference reflects and reinforces a taken-for-granted anthropocentrism among vets, animal owners and the population generally. We suggest that posthumanist ideas may offer new insights for the study of human–animal relations in organisations that transcend the coercive and negative impact of discourses that deny any alternative to prevailing farm/veterinary practices. Our study has major implications in relation to climate warming and zoonotic diseases, both partly derived from our unethical relationship to animals, that are increasingly threatening our, and their, lives. (shrink)

Nonreductive physicalism is currently one of the most widely held views about the world in general and about the status of the mental in particular. However, the view has recently faced a series of powerful criticisms from, among others, Jaegwon Kim. In several papers, Kim has argued that the nonreductivist's view of the mental is an unstable position, one harboring contradictions that push it either to reductivism or to eliminativism. The problems arise, Kim maintains, when we consider the causal powers (...) that mental properties are held to carry on the nonreductivist's view and the causal transactions into which mental events are said to enter. My aim here is less than that of defending nonreductive physicalism against all of Kim's criticisms. I wish primarily to call into question the claim that nonreductive physicalism is committed to emergentism with respect to the causal powers of the mental. As subsidiary points, I shall offer a limited defense of nonreductivism against two related objections that Kim raises. However, even if my conclusions are correct, problems remain for the nonreductivist's treatment of mental causation. I shall close the paper with a brief discussion of these difficulties. (shrink)

A popular goal in psychological science is to understand human cognition and behavior in the ‘real world’. In contrast, researchers have typically conducted their research in experimental research settings, a.k.a. the ‘psychologist’s laboratory’. Critics have often questioned whether psychology’s laboratory experiments permit generalizable results. This is known as the ‘real-world or the lab’-dilemma. To bridge the gap between lab and life, the concept of ecological validity has been widely used to evaluate whether laboratory experiments resemble and generalize to the ‘real (...) world’. However, researchers seldom define what they mean with this concept, nor are there any guidelines or criteria available for evaluating a study’s ecological validity. In our view, the popular concept of ecological validity is ill-formed, lacks specificity, and falls short of adequately addressing the fundamental problem of generalizability. In order to move beyond this ‘real-world or the lab’-dilemma, we believe that researchers should be more specific about the contexts of behaviors they are interested in, instead of aiming to understand human cognition and behavior in the ‘real world’. We argue that this is a more constructive way of uncovering the context-specific and context-generic principles of human cognition and behavior. (shrink)