With multi-year funding from the U.S. National Science Foundation (NSF), a team of researchers has just released a comprehensive report detailing ethical issues arising from human enhancement (Allhoff et al. 2009). While we direct the interested reader to that (much longer) report, we also thank the editors of this journal for the invitation to provide an executive summary thereof. This summary highlights key results from each section of that report and does so in a self-standing way; in other words, this (...) summary presupposes no familiarity with the report and offers the opportunity to gain quick familiarity with its most central findings. (shrink)

Robust technological enhancement of core cognitive capacities is now a realistic possibility. From the perspective of neutralism, the view that justifications for public policy should be neutral between reasonable conceptions of the good, only members of a subset of the ethical concerns serve as legitimate justifications for public policy regarding robust technological enhancement. This paper provides a framework for the legitimate use of ethical concerns in justifying public policy decisions regarding these enhancement technologies by evaluating the ethical concerns that arise (...) in the context of testing such technologies on nonhuman animals. Traditional issues in bioethics, as well as novel concerns such as the possibility of moral status enhancement, are evaluated from the perspective of neutralism. (shrink)

Cognitive enhancement may be defined as the amplification or extension of core capacities of the mind through improvement or augmentation of internal or external information processing systems. Cognition refers to the processes an organism uses to organize information. These include acquiring information (perception), selecting (attention), representing (understanding) and retaining (memory) information, and using it to guide behavior (reasoning and coordination of motor outputs). Interventions to improve cognitive function may be directed at any of these core faculties.

Abstract: This article begins by showing how recent controversies over the widespread promotion of artificially gene-altered foods are rooted in opposing ethical and ideological worldviews. It then explains how these contrasting worldviews have led to a practical, ethical, and ideological standoff and, finally, suggests the combined use of casuistry and virtue ethics as a way for both sides to move ahead on this pressing issue.

Bettina Schöne-Seifert and Marco Stier present a host of detailed and intriguing arguments to the effect that potentiality arguments have to be viewed as outdated due to developments in stem cell research, in particular the possibility of re-setting the development potential of differentiated cells, such as skin cells. However, their argument leaves them without an explanation of the intuitive difference between skin cells and human beings, which seems to be based on the assumption that a skin cell is merely part (...) of a human organism, while an embryo is at some point a human organism. An appropriately designed concept of the human organism can explain the difference, but also has the potential of re-dividing the argumentative landscape along familiar lines. (shrink)

Businesses that produce bioscience products—gene tests and therapies, pharmaceuticals, vaccines, and medical devices—are regularly confronted with ethical issues concerning these technologies. Conflicts exist between those who support advancements in bioscience and those who fear the consequences of unfettered scientific license. As the debate surrounding bioscience grows, it will be increasingly important for business managers to consider the larger consequences of their work. This groundbreaking book follows industry research, development, and marketing of medical and bioscience products across a variety of fields, (...) including biotechnology, pharmaceuticals, and bio-agriculture. Compelling and current case studies highlight the ethical decisions business managers frequently face. With the increasing visibility and public expectation placed on businesses in this sector, managers need to understand the ethical and social issues. This book addresses that need and provides a framework for incorporating ethical analysis in business decision making. (shrink)

Recent advancements in stem-cell research have given scientists hope that new technologies will soon enable them to grow a variety of organs for transplantation into humans. Though such developments are still in their early stages, romantic prognosticators are hopeful that scientists will be capable of growing fully functioning and complex organs, such as hearts, kidneys, muscles, and livers. This raises the question of whether such profound medical developments might have other potentially fruitful applications. In the spirit of innovation, this paper (...) examines the ethical ramifications of a spin-off technology that has just begun being considered by scientists and enthusiastic entrepreneurs: animal organs grown, independently of their host animals, for food. -/- Most importantly, this paper presents the homegrown organs market as a philosopher's Gedankenexperiment come true. By comparing three of the primary arguments against the use of animals for meat production -- Peter Singer's Utilitarianism, Tom Regan's Kantianism, and Cora Diamond's non-cognitivism -- this paper proposes that the case of organs grown in a laboratory for food further accentuates the point that the critical moral difference between an animal and a slab of meat lies in the way in which the animal interacts with us, not in specific attributes or values intrinsic to that animal. It suggests that our main impetus for not eating, and even for protecting, animals ought to be grounded in our sense of who we are, in our own practical identity as ethical agents, which develops over a long course of interactive interrelations with human and non-human others. (shrink)

Some believe that the harm or benefit of existence is assessed by comparing a person's actual state of wellbeing with the level of wellbeing they would have had had they never existed. This approach relies on ascribing a state or level of wellbeing to ‘nonexistent people’, which seems a peculiar practice: how can we attribute wellbeing to a ‘nonexistent person'? To explain away this oddity, some have argued that because no properties of wellbeing can be attributed to ‘nonexistent people’ such (...) people may be ascribed a neutral or zero level of wellbeing, setting the baseline for comparatively assessing the harm or benefit of coming into existence. However, this line of argumentation conflates the category of having zero wellbeing with the category of having no wellbeing. No Φ, unlike a zero level of Φ, is not comparable to levels of Φ — neutral, positive, or negative. Considering the nature of wellbeing and the fact that ‘nonexistent people’ cannot (metaphysically or conceptually) have wellbeing determinative properties, it follows that ‘nonexistent people’ have no wellbeing rather than zero wellbeing. (shrink)

Topic Read 01. Jan 09 Introduction/Pretest/Critical Thinking 02. Jan 11 Ethical Theory Homepage 03. Jan 16 More about Ethical Theory 04. Jan 18 Euthanasia CC-2 05. Jan 23 More about Euthanasia CC-4 06. Jan 25 Birth Defects CC-9 07. Jan 30 Euthanasia/Birth Defects Symposium 08. Feb 01 Animals as Research Subjects CC-10 09. Feb 06 More about Animals as Research Subjects 10. Feb 08 Humans as Research Subjects CC-11 11. Feb 13 Organ/Tissue Donation & Xenografts CC-13/14 12. Feb 15 Research (...) Symposium 13. Feb 20 MID-TERM EXAM 14. Feb 22 Sexual Orientation/Discrimination 15. Feb 27 Human Sexuality/Sexual Ethics Homepage 16. Mar 01 Human Sexuality Symposium 17. Mar 06 Pharmaceuticals & Empiricism 18. Mar 08 Recreational Drugs 19. Mar 20 HIV/AIDS CC-17 20. Mar 22 Contraception 21. Mar 27 Drugs/AIDS Symposium 22. Mar 29 Abortion CC-5 23. Apr 03 More about Abortion 24. Apr 05 Abortion Symposium 25. Apr 10 Assisted Reproduction CC-6 26. Apr 12 Cloning and Stem Cell Research CC-7/8 27. Apr 17 Cloning and Stem Cell Research Symposium 28. Apr 19 LATE-TERM EXAM 29. Apr 24 Medicare/HMO CC-18 30. Apr 26 Medicare/HMO Symposium.. (shrink)

The defining debate in this new century will be about technology and human enhancement, according to many across the political spectrum. Our ability to use science to enhance our bodies and minds – as opposed to its application for therapeutic purposes – is one of the most personal and therefore passionate issues in an era where emerging technologies seduce us with new and fantastic possibilities for our future. But in the process, we are forced to rethink what it means to (...) be human or, essentially, our own identity. For some, technology holds the promise of making us superhuman; for others, it offers a darker path toward becoming Frankenstein’s monster. (shrink)

The debate over the use of genetically-modified (GM) crops is one where the heat to light ratio is often quite low. Both proponents and opponents of GM crops often resort more to rhetoric than argument. This paper attempts to use Philip Kitcher’s idea of a “well-ordered science” to bring coherence to the debate. While I cannot, of course, here decide when and where, if at all, GM crops should be used I do show how Kitcher’s approach provides a useful framework (...) in which to evaluate the desirability of using GM crops. At the least Kitcher’s approach allows us to see that the current state of research in to, and use of, GM crops is very far from the ideal of a well-ordered science and gives us a goal to work towards if we wish to achieve a more well-ordered agricultural policy. (shrink)

: The current difference in attitude toward germ-line enhancement in humans and nonhumans is unjustified. Society should be more cautious in modifying the genes of nonhumans and more bold in thinking about modifying our own genome. I identify four classes of arguments pertaining to germ-line enhancement: safety arguments, justice arguments, trust arguments, and naturalness arguments. The first three types are compelling, but do not distinguish between human and nonhuman cases. The final class of argument would justify a distinction between human (...) and nonhuman germ-line enhancement; however, this type of argument fails and, therefore, the discrepancy in attitude toward human and nonhuman germ-line enhancement is unjustified. (shrink)

A number of controversial topics related to bioethics and biotechnology 17 papers that deal with various aspects of release and development of genetically modified organisms (GMOs), stem cells and cloning, privacy and bio-banking.

The procurement of fetal tissue for transplantation may promise great benefit to those suffering from various pathologies, e.g., neural disorders, diabetes, renal problems, and radiation sickness. However, debates about the use of fetal tissue have proceeded without much attention to ethical theory and application. Two broad moral questions are addressed here, the first formal, the second substantive: Is there a framework from other moral paradigms to assist in ethical debates about the transplantation of fetal tissue? Does the use of fetal (...) tissue entail cooperation in abortion? To answer these questions I develop a theoretical framework by combining the paradigm of just-war reasoning with canons governing the use of cadaverous tissue. The kinds of safeguards provided by this paradigm allow fetal tissue to be procured without the taint of association with abortion. Central to solving the problem of cooperation is the distinction between intending and foreseeing a moral misdeed. Fetal researchers may foresee fetal death in elective abortions without intending such deaths to occur. Thus, even those who object unequivocally to elective abortion may condone the procurement of fetal tissue, if sufficient reason exists. Keywords: fetal tissue, casuistry, prima facie duties, just-war tenets, complicity CiteULike Connotea Del.icio.us What's this? (shrink)

Over the past decades, mood enhancement effects of various drugs and neuromodulation technologies have been proclaimed. If one day highly effective methods for significantly altering and elevating one’s mood are available, it is conceivable that the demand for them will be considerable. One urgent concern will then be what role physicians should play in providing such services. The concern can be extended from literature on controversial demands for aesthetic surgery. According to Margaret Little, physicians should be aware that certain aesthetic (...) enhancement requests reflect immoral social norms and ideals. By granting such requests, she argues, doctors render themselves complicit to a collective ‘evil’. In this paper, we wish to question the extent to which physicians, psychiatrists and/or neurosurgeons should play a role as ‘moral gatekeepers’ in dealing with suspect demands and norms underlying potential desires to alter one’s mood or character. We investigate and discuss the nature and limits of physician responsibilities in reference to various hypothetical and intuitively problematic mood enhancement requests. (shrink)

In general, to enhance something is to raise that thing in degree, intensity, magnitude, or in some sense improve upon it.2 In this context, we are concerned with enhancements, ie amplifications or extensions, of human capabilities, ...

Though the vegetarian movement sparked by Peter Singer’s book Animal Liberation has achieved some success, there is more animal suffering caused today due to factory farming than there was when the book was originally written. In this paper, I argue that there may be a technological solution to the problem of animal suffering in intensive factory farming operations. In particular, I suggest that recent research indicates that we may be very close to, if not already at, the point where we (...) can genetically engineer factory-farmed livestock with a reduced or completely eliminated capacity to suffer. In as much as animal suffering is the principal concern that motivates the animal welfare movement, this development should be of central interest to its adherents. Moreover, I will argue that all people concerned with animal welfare should agree that we ought to replace the animals currently used in factory farming with animals whose ability to suffer is diminished if we are able to do so. (shrink)

The intellectual property regimes we have currently in place are heavily under attack. One of the points of criticism is the interaction between two elements of article 27 of the Universal Declaration of Human Rights, the widely discussed issue of being able to benefit from scientific progress and the less argued for position of having a right to take part in scientific enterprises. To shine light on the question if we should balance the two elements or prioritize one of them, (...) an exploration will be offered on how benefiting from scientific progress and the ability to participate in the advancement of science relate to securing human capabilities. A different perspective to the question will be gained by identifying the problem as an issue of misrecognition, especially the failure to recognize many willing collaboration partners in scientific research as peers. Lastly, I will argue that cooperative justice requires that if we have an innovation incentive system that disproportionally benefits one particular group, a certain duty to counterbalance this advantage exists when we are relying on mutual cooperation for the recognition of intellectual property rights. (shrink)

Until now, philosophical debate about human embryonic stem cell (hESC) research has largely been limited to its ethical dimensions and implications. Although the importance and urgency of these ethical debates should not be underestimated, the almost undivided attention that mainstream and feminist philosophers have paid to the ethical dimensions of hESC research suggests that the only philosophically interesting questions and concerns about it are by and large ethical in nature. My argument goes some distance to challenge the assumption that ethical (...) considerations alone must be foregrounded in philosophical discussions about hESC research by introducing a critical stance on the epistemological and ontological assumptions that underlie and condition it. A central aim of the paper is to show how Foucault's insights into knowledge-power, taken in combination with Hacking's claims about styles of reasoning, can make these assumptions evident, as well as cast light on their potentially deleterious implications for disabled people. Arguing in this way also enables me to draw out constitutive effects of research on stem cells, that is, to indicate how the discursive practices surrounding research on stem cells, as well as the technology itself, contribute to the constitution of impairment. (shrink)

Ethical evaluation of deep brain stimulation as a treatment for Parkinson’s disease is complicated by results that can be described as involving changes in the patient’s identity. The risk of becoming another person following surgery is alarming for patients, caregivers and clinicians alike. It is one of the most urgent conceptual and ethical problems facing deep brain stimulation in Parkinson’s disease at this time. In our paper we take issue with this problem on two accounts. First, we elucidate what is (...) meant by becoming another person from a conceptual point of view. After critically discussing two broad approaches we concentrate on the notion of individual identity which centers on the idea of core attitudes . Subsequently we discuss several approaches to determine what distinguishes core attitudes from those that are more peripheral. We argue for a foundational-function model highlighting the importance of specific dependency relations between these attitudes. Our second aim is to comment on the possibility to empirically measure changes in individual identity and argue that many of the instruments now commonly used in selecting and monitoring DBS-patients are inappropriate for this purpose. Future research in this area is advised combining a conceptual and an empirical approach as a basis of sound ethical appraisal. (shrink)

The time is near where ‘therapeutic’ bodily assistive devices, developed to mimic species-typical body structures in order to enable normative body functioning, will allow the wearer to outperform the species-typical body in various functions. Although such devices are developed for people that are seen to exhibit sub species-typical abilities, many ‘therapeutic enhancements’ might also be desired and used by people that exhibit species-typical body abilities. This paper presents the views of members of the World Federation of the Deaf on potential (...) beyond species-typical abilities enabling therapeutic assistive devices (i.e. related to hearing). Survey respondents showed support for the development and uptake of beyond normal hearing enabling devices. The views of survey respondents as clients affect hearing-enabling professions (such as audiologist and speech pathologists). The paper analyzes what guidance code of ethics of hearing enabling professions give in regards to beyond normal hearing enabling devices. This paper suggests that people labeled impaired and the professions that serve them should more involved in the enhancement discourse. (shrink)