In this wide-ranging and multidisciplinary volume, leading scholars, activists, journalists, and public figures deliberate about the creative and critical potential of public imagination in an era paradoxically marked by intensifying globalization and resurgent nationalism. Divided into five sections, these essays explore the social, political, and cultural role of imagination and civic engagement, offering cogent, ingenious reflections that stand in stark contrast to the often grim rhetoric of our era. Short and succinct, the essays engage with an interconnected ensemble of themes (...) and issues while also providing insights into the specific geographical and social dynamics of each author's national or regional context. Part 1 introduces the reader to theoretical reflections on imagination and the public sphere; Part 2 illustrates dynamics of public imagination in a diverse set of cultural contexts; Part 3 reflects in various ways on the urgent need for a radically transformed public and civic imagination in the face of worldwide ecological crisis; Part 4 suggests new societal possibilities that are related to spiritual as well as politically revolutionary sources of inspiration; Part 5 explores characteristics of present and potentially emerging global society and the existing transnational framework that could provide resources for a more humane global order. Erudite and thought-provoking, On Public Imagination makes a vital contribution to political thought, and is accessible to activists, students, and scholars alike. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Killing God, Liberating the “Subject”: Nietzsche and Post-God FreedomMichael LackeyIIndeed, we philosophers and “free spirits” feel, when we hear the news that “the old god is dead,” as if a new dawn shone on us; our heart overflows with gratitude, amazement, premonitions, expectations. 1After God’s death, if Michel Foucault is to be believed, the death of the subject followed quite naturally. But how, one might ask, did that fateful (...) event of God’s death necessarily lead to the demise of that most noble animal? Answering this question is crucial, for once we understand how, for Nietzsche, God’s existence and His metaphorical participation in the creation of humanity are most destructive of what is most vital within the human, then we will see how, in killing God and His crown of creation, Nietzsche does not become the quintessential nihilist; rather, he becomes, to his mind, the first sane voice crying in the intellectual wilderness: make way the coming of a new human, a “subject” which can only become a “self “ when it paradoxically learns to overcome its very constructed “self.” Nietzsche’s logic therefore runs as follows: so long as God exists, a subject which overcomes itself cannot come into being; for as Richard Schacht rightly notes, the God-hypothesis serves as a support for the traditional subject-hypothesis in Nietzsche’s writings. So to produce a self-overcoming subject Nietzsche must first kill what he considers that stodgy old tyrant of the soul. But this raises the question of how one goes about doing away with [End Page 737] God. In Twilight of the Idols Nietzsche gives his reader a puzzling answer to this question when he says that he fears that “we are not getting rid of God because we still believe in grammar” (“Reason,” 5). 2 Given Nietzsche’s logic, to kill off God he needs to eliminate belief in grammar, and once God is dead, he can then do away with the subject. In what follows I will show how Nietzsche tries to eliminate God and the traditional subject through his extended analysis of what it means to “believe in grammar.”IIIf there is today still no lack of those who do not know how indecent it is to “believe”—or a sign of decadence, of a broken will to live—well, they will know it tomorrow. 3To understand what it means to believe in grammar, it is best to note how Nietzsche contrasts belief and freedom. More starkly, we could say that for Nietzsche to have faith means, necessarily, to lack freedom; or to be free means, necessarily, to reject faith. Nietzsche makes this clear in the fifth book of GS when he says: “Once a human being reaches the fundamental conviction that he must be commanded, he becomes ‘a believer.’ Conversely, one could conceive of such a pleasure and power of self determination, such a freedom of the will that the spirit would take leave of all faith and every wish for certainty, being practiced in maintaining himself on insubstantial ropes and possibilities and dancing even near abysses” (§ 347). I isolate this passage not in order to outline Nietzsche’s criticism of belief but rather to understand how Nietzsche defines freedom by contrasting it with belief. Such an analysis of course begs the question how it is possible that belief necessarily precludes freedom. Intuitively, it would seem that belief and freedom entail no contradiction. For instance, given two choices, to believe in God or not to believe in God, I exercise my freedom in choosing one belief over the other. With this example, it would seem that belief necessarily presupposes freedom. So how is it that Nietzsche concludes that freedom and belief are irreconcilable?That Nietzsche considers faith obscene is clear when he tells us in AC that belief of any kind is a “sign of decadence” (§ 50) which leads to “self-alienation” (§ 54). In fact he goes so far as to claim that faith is actually “slavery in a higher sense” (§ 54). To see why belief implies slavery we must first understand what Nietzsche means by faith. While the standard view suggests that faith is... (shrink)

Evolutionary ethics - the application of evolutionary ideas to moral thinking and justification - began in the nineteenth century with the work of Charles Darwin and Herbert Spencer, but was subsequently criticized as an example of the naturalistic fallacy. In recent decades, however, evolutionary ethics has found new support among both the Darwinian and the Spencerian traditions. This accessible volume looks at the history of thought about evolutionary ethics as well as current debates in the subject, examining first the claims (...) of supporters and then the responses of their critics. Topics covered include social Darwinism, moral realism, and debunking arguments. Clearly written and structured, the book guides readers through the arguments on both sides, and emphasises the continuing relevance of evolutionary theory to our understanding of ethics today. (shrink)

This seriously playful book provides comic relief in an age of neoliberalism and argues that parody can be used to creatively benefit our practices of self-narration and quests for knowledge. It demonstrates how parody utilizes humor, play, and self-reflection to allow for a helpful, alternative relationship to mistakes and our multifaceted-self. The book works to delineate specific ways of viewing, studying, creating, and performing a particular form of humorous parody, and through pedagogical application, it balances practical hands on examples via (...) digital video creation with examples and exercises such as interrogating our creative histories and parodying them--either as a classroom exercise or in individual self-reflection. The core readership for this book is rhetoric and composition scholars researching continental philosophy, humor, and narrative theory, and it lends itself to classroom implementation for professors, as it brings together (often for the first time) major academic conversations on humor throughout philosophy, literary and cultural studies, communication studies, and media studies. Therefore, this book will be essential reading for undergraduate/graduate courses that feature humor, alternative forms of communication in the public sphere, alternative rhetorical strategies, and courses that focus on the importance of creativity and play in our daily lives and scholarship. (shrink)

No doubt most philosophers who spend time on the history of philosophy are familiar with that question asked to embarrass (and liable to be asked by scientists in particular) why the history of the subject should be thought a significant part of the subject itself. Either there is progress in philosophy, it is said, or there is not. If there is progress, why the laborious backward glances? How can the past be so important? Why aren’t philosophers like psychologists, given perhaps (...) a short historical orientation before being brought up to the nitty-gritty of the present? If, on the other hand, there is no progress, if we might as well be discussing Locke as Quine, doesn’t that imply that philosophy consists in a set of questions for which there is no way of establishing even that some answers are better than others? Wouldn’t it be more profitable to pursue questions to which at least provisional answers can be established, approximating to the truth? Wouldn’t it be better to be a scientist? (shrink)

The Origin of Species by Charles Darwin is universally recognized as one of the most important science books ever written. Published in 1859, it was here that Darwin argued for both the fact of evolution and the mechanism of natural section. The Origin of Species is also a work of great cultural and religious significance, in that Darwin maintained that all organisms, including humans, are part of a natural process of growth from simple forms. This Companion commemorates the 150th anniversary (...) of the publication of the Origin of Species and examines its main arguments. Drawing on the expertise of leading authorities in the field, it also provides the contexts - religious, social, political, literary, and philosophical - in which the Origin was composed. Written in a clear and friendly yet authoritative manner, this volume will be essential reading for both scholars and students More broadly, it will appeal to general readers who want to learn more about one of the most important and controversial books of modern times. (shrink)

The ethical issues raised by cybersecurity practices and technologies are of critical importance. However, there is disagreement about what is the best ethical framework for understanding those issues. In this paper we seek to address this shortcoming through the introduction of a principlist ethical framework for cybersecurity that builds on existing work in adjacent fields of applied ethics, bioethics, and AI ethics. By redeploying the AI4People framework, we develop a domain-relevant specification of five ethical principles in cybersecurity: beneficence, non-maleficence, autonomy, (...) justice, and explicability. We then illustrate the advantages of this principlist framework by examining the ethical issues raised by four common cybersecurity contexts: penetration testing, distributed denial of service attacks (DDoS), ransomware, and system administration. These case analyses demonstrate the utility of this principlist framework as a basis for understanding cybersecurity ethics and for cultivating the ethical expertise and ethical sensitivity of cybersecurity professionals and other stakeholders. (shrink)

Focused sequent calculi are a refinement of sequent calculi, where additional side-conditions on the applicability of inference rules force the implementation of a proof search strategy. Focused cut-free proofs exhibit a special normal form that is used for defining identity of sequent calculi proofs. We introduce a novel focused display calculus fD.LG and a fully polarized algebraic semantics FP.LG\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathbb {FP.LG}$$\end{document} for Lambek–Grishin logic by generalizing the theory of multi-type calculi and their (...) algebraic semantics with heterogenous consequence relations. The calculus fD.LG has strong focalization and it is sound and complete w.r.t. FP.LG\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathbb {FP.LG}$$\end{document}. This completeness result is in a sense stronger than completeness with respect to standard polarized algebraic semantics, insofar as we do not need to quotient over proofs with consecutive applications of shifts over the same formula. We also show a number of additional results. fD.LG is sound and complete w.r.t. LG-algebras: this amounts to a semantic proof of the so-called completeness of focusing, given that the standard (display) sequent calculus for Lambek–Grishin logic is complete w.r.t. LG-algebras. fD.LG and the focused calculus fLG of Moortgat and Moot are equivalent with respect to proofs, indeed there is an effective translation from fLG-derivations to fD.LG-derivations and vice versa: this provides the link with operational semantics, given that every fLG-derivation is in a Curry–Howard correspondence with a directional λ¯μμ~\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\overline{\lambda }\mu \widetilde{\mu }$$\end{document}-term. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

Sainsbury and Tye present a new theory, 'originalism', which provides natural, simple solutions to puzzles about thought that have troubled philosophers for centuries. They argue that concepts are to be individuated by their origin, rather than epistemically or semantically. Although thought is special, no special mystery attaches to its nature.

Conflicts of interest pose special problems for the professions. Even the appearance of a conflict of interest can undermine essential trust between professional and public. This volume is a comprehensive and accessible guide to the ramifications and problems associated with important issue. It contains fifteen new essays by noted scholars and covers topics in law, medicine, journalism, engineering, financial services, and others.

There are many kinds of epistemic experts to which we might wish to defer in setting our credences. These include: highly rational agents, objective chances, our own future credences, our own current credences, and evidential probabilities. But exactly what constraint does a deference requirement place on an agent's credences? In this paper we consider three answers, inspired by three principles that have been proposed for deference to objective chances. We consider how these options fare when applied to the other kinds (...) of epistemic experts mentioned above. Of the three deference principles we consider, we argue that two of the options face insuperable difficulties. The third, on the other hand, fares well|at least when it is applied in a particular way. (shrink)

Rudolf Carnap is increasingly regarded as one of the most important philosophers of the twentieth century. He was one of the leading figures of the logical empiricist movement associated with the Vienna Circle and a central figure in the analytic tradition more generally. He made major contributions to philosophy of science and philosophy of logic, and, perhaps most importantly, to our understanding of the nature of philosophy as a discipline. In this volume a team of contributors explores the major themes (...) of his philosophy and discusses his relationship with the Vienna Circle and with philosophers such as Frege, Husserl, Russell, and Quine. New readers will find this the most convenient and accessible guide to Carnap currently available. Advanced students and specialists will find a conspectus of recent developments in the interpretation of Carnap. (shrink)

In this introduction to the Oxford Handbook of Philosophy and Psychoanalysis, we provide an overview of the promise and problems of connecting philosophy and psychoanalysis through a focus on the age-old theme central to both disciplines, 'know thyself'.

During the last 25 years, researchers studying human reasoning and judgment in what has become known as the “heuristics and biases” tradition have produced an impressive body of experimental work which many have seen as having “bleak implications” for the rationality of ordinary people (Nisbett and Borgida 1975). According to one proponent of this view, when we reason about probability we fall victim to “inevitable illusions” (Piattelli-Palmarini 1994). Other proponents maintain that the human mind is prone to “systematic deviations from (...) rationality” (Bazerman & Neale 1986) and is “not built to work by the rules of probability” (Gould 1992). It has even been suggested that human beings are “a species that is uniformly probability-blind” (Piattelli-Palmarini 1994). This provocative and pessimistic interpretation of the experimental findings has been challenged from many different directions over the years. One of the most recent and energetic of these challenges has come from the newly emerging field of evolutionary psychology, where it has been argued that it’s singularly implausible to claim that our species would have evolved with no “instinct for probability” and, hence, be “blind to chance” (Pinker 1997, 351). Though evolutionary psychologists concede that it is possible to design experiments that “trick our probability.. (shrink)

This article is concerned with developing a philosophical approach to a number of significant changes to academic publishing, and specifically the global journal knowledge system wrought by a range of new digital technologies that herald the third age of the journal as an electronic, interactive and mixed-media form of scientific communication. The paper emerges from an Editors' Collective, a small New Zealand-based organisation comprised of editors and reviewers of academic journals mostly in the fields of education and philosophy. The paper (...) is the result of a collective writing process. (shrink)

Although Responsible Conduct of Research training is common in the sciences, the effectiveness of RCR training is open to question. Three key factors appear to be particularly important in ensuring the effectiveness of ethics education programs: educational efforts should be tied to day-to-day practices in the field, educational efforts should provide strategies for working through the ethical problems people are likely to encounter in day-to-day practice, and educational efforts should be embedded in a broader program of on-going career development efforts. (...) This article discusses a complex qualitative approach to RCR training development, based on a sensemaking model, which strives to address the afore-mentioned training concerns. Ethnographic observations and prior RCR training served the purpose of collecting information specific to a multi-disciplinary and multi-university research center with the goal of identifying metacognitive reasoning strategies that would facilitate ethical decision-making. The extensive qualitative analyses resulted in the identification of nine metacognitive reasoning strategies on which future RCR training will be developed. The implications of the findings for RCR training in the sciences are discussed. (shrink)

This engaging and accessible introduction to the philosophy of language provides an important guide to one of the liveliest and most challenging areas of study in philosophy. Interweaving the historical development of the subject with a thematic overview of the different approaches to meaning, the book provides students with the tools necessary to understand contemporary analytical philosophy. The second edition includes new material on: Chomsky, Wittgenstein and Davidson as well as new chapters on the causal theory of reference, possible worlds (...) semantics and semantic externalism. (shrink)

This article reviews current methods for evaluating models in the cognitive sciences, including theoretically based approaches, such as Bayes factors and minimum description length measures; simulation approaches, including model mimicry evaluations; and practical approaches, such as validation and generalization measures. This article argues that, although often useful in specific settings, most of these approaches are limited in their ability to give a general assessment of models. This article argues that hierarchical methods, generally, and hierarchical Bayesian methods, specifically, can provide a (...) more thorough evaluation of models in the cognitive sciences. This article presents two worked examples of hierarchical Bayesian analyses to demonstrate how the approach addresses key questions of descriptive adequacy, parameter interference, prediction, and generalization in principled and coherent ways. (shrink)

_Education, Ethics and Experience_ is a collection of original philosophical essays celebrating the work of one of the most influential philosophers of education of the last 40 years. Richard Pring’s substantial body of work has addressed topics ranging from curriculum integration to the comprehensive ideal, vocational education to faith schools, professional development to the privatisation of education, moral seriousness to the nature of educational research. The twelve essays collected here explore and build on Pring’s treatment of topics that are (...) central to the field of philosophy of education and high on the agenda of education policy-makers. The essays are by no means uncritical: some authors disagree sharply with Pring; others see his arguments as useful but incomplete, in need of addition or amendment. But all acknowledge their intellectual debt to him and recognise him as a giant on whose shoulders they stand. This book will be a welcome and lively read for educational academics, researchers and students of Educational Studies and Philosophy. (shrink)

Richard Jeffrey, Michael Hendrickson; XIV*—Probabilizing Pathology, Proceedings of the Aristotelian Society, Volume 89, Issue 1, 1 June 1989, Pages 211–226, htt.

When it first appeared in 1979, Philosophy and the Mirror of Nature hit the philosophical world like a bombshell. In it, Richard Rorty argued that, beginning in the seventeenth century, philosophers developed an unhealthy obsession with the notion of representation: comparing the mind to a mirror that reflects reality. Rorty's book is a powerful critique of this imagery and the tradition of thought that it spawned. Thirty years later, the book remains a must-read and stands as a classic of (...) twentieth-century philosophy. Its influence on the academy, both within philosophy and across a wide array of disciplines, continues unabated. This edition includes new essays by philosopher Michael Williams and literary scholar David Bromwich, as well as Rorty's previously unpublished essay "The Philosopher as Expert.". (shrink)

Orang-utans played a communication game in two studies testing their ability to produce and comprehend requestive pointing. While the ‘communicator’ could see but not obtain hidden food, the ‘donor’ could release the food to the communicator, but could not see its location for herself. They could coordinate successfully if the communicator pointed to the food, and if the donor comprehended his communicative goal and responded pro-socially. In Study 1, one orang-utan pointed regularly and accurately for peers. However, they responded only (...) rarely. In Study 2, a human experimenter played the communicator’s role in three conditions, testing the apes’ comprehension of points of different heights and different degrees of ostension. There was no effect of condition. However, across conditions one donor performed well individually, and as a group orang-utans’ comprehension performance tended towards significance. We explain this on the grounds that comprehension required inferences that they found difficult – but not impossible. The finding has valuable implications for our thinking about the development of pointing in phylogeny. (shrink)

Psychoanalysis is often equated with Sigmund Freud, but this comparison ignores the wide range of clinical practices, observational methods, general theories, and cross-pollinations with other disciplines that characterise contemporary psychoanalytic work. Central psychoanalytic concepts to do with unconscious motivation, primitive forms of thought, defence mechanisms, and transference form a mainstay of today's richly textured contemporary clinical psychological practice. -/- In this landmark collection on philosophy and psychoanalysis, leading researchers provide an evaluative overview of current thinking. Written at the interface between (...) these two disciplines, the Oxford Handbook of Philosophy and Psychoanalysis contains original contributions that will shape the future of debate. With 34 chapters divided into eight sections covering history, clinical theory, phenomenology, science, aesthetics, religion, ethics, and political and social theory, this Oxford Handbook displays the enduring depth, breadth, and promise of integrating philosophical and psychoanalytic thought. -/- Anyone interested in the philosophical implications of psychoanalysis, as well as philosophical challenges to and re-statements of psychoanalysis, will want to consult this book. It will be a vital resource for academic researchers, psychoanalysts and other mental health professionals, graduates, and trainees. (shrink)

Infants can see someone pointing to one of two buckets and infer that the toy they are seeking is hidden inside. Great apes do not succeed in this task, but, surprisingly, domestic dogs do. However, whether children and dogs understand these communicative acts in the same way is not yet known. To test this possibility, an experimenter did not point, look, or extend any part of her body towards either bucket, but instead lifted and shook one via a centrally pulled (...) rope. She did this either intentionally or accidentally, and did or did not address her act to the subject using ostensive cues. Young 2-year-old children but not dogs understood the experimenter’s act in intentional conditions. While ostensive pulling of the rope made no difference to children’s success, it actually hindered dogs’ performance. We conclude that while human children may be capable of inferring communicative intent from a wide variety actions, so long as these actions are performed intentionally, dogs are likely to be less flexible in this respect. Their understanding of communicative intention may be more dependent upon bodily markers of communicative intent, including gaze, orientation, extended limbs, and vocalisations. This may be because humans have come under selective pressure to develop skills for communicating with absent interlocutors – where bodily co-presence is not possible. (shrink)

Gave 42 19-26 yr. old insomniac Ss placebo pills to take a few min. before going to bed. Some Ss were told that the pills would cause arousal, and others were told that the pills would reduce arousal. As predicted, arousal Ss got to sleep more quickly than they had on nights without the pills, presumably because they attributed their arousal to the pills rather than to their emotions, and as a consequence were less emotional. Also as predicted, relaxation Ss (...) got to sleep less quickly than usual, presumably because they assumed that their emotions were unusually intense since their arousal level was high even after taking an arousal-reducing agent. Results have relevance for S. Schachter's theory of emotions and H. Kelley's attribution theory. Pragmatically, findings suggest the feasibility of a therapy based on reattribution of symptoms, and indicate that traditional suggestion effect practices should be modified. (shrink)

Dieses Lehrbuch vermittelt einen systematischen Überblick über die grundlegenden Funktionen der auf Finanzmärkten agierenden Anbieter sowie die von ihnen angebotenen Finanzdienstleistungen. Sein Spektrum reicht von der Finanzierung und Vermögensanlage bei Banken und Versicherungen über die verschiedenen Formen von Wertpapier- und Wertpapiertermingeschäften bis hin zum Abschluss von Versicherungsverträgen und ähnlichen Maßnahmen zur Risikoverlagerung. In der Neuauflage werden wiederum zahlreiche Entwicklungen der letzten Jahre wie etwa Mittelstandsanleihen, Exchange-Traded Funds oder Derivatgeschäfte von Kommunen in die Betrachtung einbezogen. Das Kapitel über Wertpapiertermingeschäfte wurde grundlegend (...) neu gestaltet. Für Studierende wirtschaftswissenschaftlicher Studiengänge, Praktiker in der Finanzdienstleistungsbranche, Mitarbeiter in Kämmereien oder Finanzabteilungen privater und öffentlicher Unternehmen sowie Angehörige der Steuer- und rechtsberatenden Berufe, die im Zuge ihrer Beratungstätigkeit mit Finanzdienstleistungen konfrontiert werden. (shrink)

The communicative interactions of very young children almost always involve language, gesture and directed gaze. In this study, ninety-six children were asked to determine the location of a hidden toy by understanding a communicative act that contained none of these familiar means. A light-and-sound mechanism placed behind the hiding place and illuminated by a centrally placed switch was used to indicate the location of the toy. After a communicative training session, an experimenter pressed the switch either deliberately or accidentally, and (...) with or without ostension. In no condition did she orient towards the hiding place. When the switch was pressed intentionally, children used the light-and-sound cue to find the toy – and tended to do so even in the absence of ostensive eye contact. When the experimenter pressed the switch accidentally, children searched randomly – demonstrating that they were tracking her communicative intent, and not merely choosing on the basis of salience. The absence of an effect of ostension contradicts research that ostension helps children to interpret the communicative intentions underlying unfamiliar signs. We explain this by concluding that while it may play a role in establishing a communicative interaction, it is not necessary for sustaining one; and that even with a highly novel communicative act – involving none of the means of communication on which children typically rely – three-year-olds can comprehend the communicative intentions behind an intentionally produced act. (shrink)

Objectivity in the sciences is a much-touted yet problematic concept. It is sometimes held up as characterising scientific knowledge, yet operational definitions are diverse and call for such paradoxical genius as the ability to see without a perspective, to predict repeatability, to elicit nature’s own self-revelation, or to discern the structure of reality with inerrancy. Here we propose a positive and general definition of objectivity based on work in the Reformational philosophy tradition. We recognise a suite of relation-frames–ways in which (...) things function and relate to each other, which can be analytically distinguished in the process of conceptual abstraction. These relation-frames also ground the diverse aspects of scientific analysis within which relationships and properties may be abstracted from entities and systems. We argue that objectivity can be understood as characteristic of representations that attempt to portray a subject in an earlier relation-frame than that in which it characteristically functions. In short, objectivity is projection. This proposal is exemplified from mathematics and the natural sciences and some possible objections to it are considered, as well as its extension to the social sciences. (shrink)

Clustered regularly interspaced short palindromic repeats genome editing has already reinvented the direction of genetic and stem cell research. For more complex diseases it allows scientists to simultaneously create multiple genetic changes to a single cell. Technologies for correcting multiple mutations in an in vivo system are already in development. On the surface, the advent and use of gene editing technologies is a powerful tool to reduce human suffering by eradicating complex disease that has a genetic etiology. Gene drives are (...) CRISPR mediated alterations to genes that allow them to be passed on to subsequent populations at rates that approach one hundred per cent transmission. Therefore, from an anticipatory biomedical ethics perspective, it is possible to conceive gene drive being used with CRISPR to permanently ameliorate aberrant genes from wild-type populations containing mutations. However, there are also a number of possible side effects that could develop as the result of combining gene editing and gene drive technologies in an effort to eradicate complex diseases. In this paper, we critically analyse the hypothesis that the combination of CRISPR and gene drive will have a deleterious effect on human populations from an ethical perspective by developing an anticipatory ethical analysis of the implications for the use of CRISPR together with gene drive in humans. (shrink)