Results for 'intragenomic conflict'

996 found
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  1. Does intragenomic conflict predict intrapersonal conflict?David Spurrett - 2016 - Biology and Philosophy 31 (3):313-333.
    Parts of the genome of a single individual can have conflicting interests, depending on which parent they were inherited from. One mechanism by which these conflicts are expressed in some taxa, including mammals, is genomic imprinting, which modulates the level of expression of some genes depending on their parent of origin. Imprinted gene expression is known to affect body size, brain size, and the relative development of various tissues in mammals. A high fraction of imprinted gene expression occurs in the (...)
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  2.  35
    Genetic dissent and individual compromise.David Haig - 2014 - Biology and Philosophy 29 (2):233-239.
    Organisms can be treated as optimizers when there is consensus among their genes about what is best to be done, but genomic consensus is often lacking, especially in interactions among kin because kin share some genes but not others. Grafen adopts a majoritarian perspective in which an individual’s interests are identified with the interests of the largest coreplicon of its genome, but genomic imprinting and recombination factionalize the genome so that no faction may predominate in some interactions among kin. Once (...)
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  3.  12
    Genomic Imprinting As a Window into Human Language Evolution.Thomas J. Hitchcock, Silvia Paracchini & Andy Gardner - 2019 - Bioessays 41 (6):1800212.
    Humans spend large portions of their time and energy talking to one another, yet it remains unclear whether this activity is primarily selfish or altruistic. Here, it is shown how parent‐of‐origin specific gene expression—or “genomic imprinting”—may provide an answer to this question. First, it is shown why, regarding language, only altruistic or selfish scenarios are expected. Second, it is pointed out that an individual's maternal‐origin and paternal‐origin genes may have different evolutionary interests regarding investment into language, and that this (...) conflict may drive genomic imprinting which—as the direction of imprint depends upon whether investment into language is relatively selfish or altruistic—may be used to discriminate between these two possibilities. Third, predictions concerning the impact of various mutations and epimutations at imprinted loci on language pathologies are derived. In doing so, a framework is developed that highlights avenues for using intragenomic conflicts to investigate the evolutionary drivers of language. (shrink)
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  4.  15
    The evolving landscape of imprinted genes in humans and mice: Conflict among alleles, genes, tissues, and kin.Jon F. Wilkins, Francisco Úbeda & Jeremy Van Cleve - 2016 - Bioessays 38 (5):482-489.
    Three recent genome‐wide studies in mice and humans have produced the most definitive map to date of genomic imprinting (gene expression that depends on parental origin) by incorporating multiple tissue types and developmental stages. Here, we explore the results of these studies in light of the kinship theory of genomic imprinting, which predicts that imprinting evolves due to differential genetic relatedness between maternal and paternal relatives. The studies produce a list of imprinted genes with around 120–180 in mice and ∼100 (...)
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  5. Configuration of Stable Evolutionary Strategy of Homo Sapiens and Evolutionary Risks of Technological Civilization (the Conceptual Model Essay).Valentin T. Cheshko, Lida V. Ivanitskaya & Yulia V. Kosova - 2014 - Biogeosystem Technique 1 (1):58-68.
    Stable evolutionary strategy of Homo sapiens (SESH) is built in accordance with the modular and hierarchical principle and consists of the same type of self-replicating elements, i.e. is a system of systems. On the top level of the organization of SESH is the superposition of genetic, social, cultural and techno-rationalistic complexes. The components of this triad differ in the mechanism of cycles of generation - replication - transmission - fixing/elimination of adoptively relevant information. This mechanism is implemented either in accordance (...)
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  6.  2
    Is genomics bad for you?Benjamin Ja Dickins - 2012 - Behavioral and Brain Sciences 35 (5):364-365.
    The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend towards its diversification and degradation. These include the accumulation of deleterious changes and intragenomic conflict.
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  7. EVOLUTIONARY RISK OF HIGH HUME TECHNOLOGIES. Article 2. THE GENESIS AND MECHANISMS OF EVOLUTIONARY RISK.V. T. Cheshko, L. V. Ivanitskaya & V. I. Glazko - 2015 - Integrative Anthropology (1):4-15.
    Sources of evolutionary risk for stable strategy of adaptive Homo sapiens are an imbalance of: (1) the intra-genomic co-evolution (intragenomic conflicts); (2) the gene-cultural co-evolution; (3) inter-cultural co-evolution; (4) techno-humanitarian balance; (5) inter-technological conflicts (technological traps). At least phenomenologically the components of the evolutionary risk are reversible, but in the aggregate they are in potentio irreversible destructive ones for biosocial, and cultural self-identity of Homo sapiens. When the actual evolution is the subject of a rationalist control and/or manipulation, the (...)
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  8.  5
    Are schizophrenics more religious? Do they have more daughters?Satoshi Kanazawa - 2008 - Behavioral and Brain Sciences 31 (3):272-273.
    Combined with recent evolutionary psychological theories, Crespi & Badcock's (C&B's) intragenomic conflict theory of the social brain suggests that schizophrenics are more religious, and autistics are less religious, than the normal population. Combined with the generalized Trivers-Willard hypothesis (gTWH), it suggests that schizophrenics have more daughters, and autistics have more sons, than expected.
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  9.  20
    The integrative framework for the behavioural sciences has already been discovered, and it is the adaptationist approach.Michael E. Price, William M. Brown & Oliver S. Curry - 2007 - Behavioral and Brain Sciences 30 (1):39-40.
    The adaptationist framework is necessary and sufficient for unifying the social and natural sciences. Gintis's “beliefs, preferences, and constraints” (BPC) model compares unfavorably to this framework because it lacks criteria for determining special design, incorrectly assumes that standard evolutionary theory predicts individual rationality maximisation, does not adequately recognize the impact of psychological mechanisms on culture, and is mute on the behavioural implications of intragenomic conflict. (Published Online April 27 2007).
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  10.  6
    Concerted evolution of ribosomal DNA: Somatic peace amid germinal strife.David Haig - 2021 - Bioessays 43 (12):2100179.
    Most eukaryotes possess many copies of rDNA. Organismal selection alone cannot maintain rRNA function because the effects of mutations in one rDNA are diluted by the presence of many other rDNAs. rRNA quality is maintained by processes that increase homogeneity of rRNA within, and heterogeneity among, germ cells thereby increasing the effectiveness of cellular selection on ribosomal function. A successful rDNA repeat will possess adaptations for spreading within tandem arrays by intranuclear selection. These adaptations reside in the non‐coding regions of (...)
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  11.  3
    Did the creeping vole sex chromosomes evolve through a cascade of adaptive responses to a selfish x chromosome?Scott William Roy - 2023 - Bioessays 45 (12):2100164.
    The creeping vole Microtus oregoni exhibits remarkably transformed sex chromosome biology, with complete chromosome drive/drag, X‐Y fusions, sex reversed X complements, biased X inactivation, and X chromosome degradation. Beginning with a selfish X chromosome, I propose a series of adaptations leading to this system, each compensating for deleterious consequences of the preceding adaptation: (1) YY embryonic inviability favored evolution of a selfish feminizing X chromosome; (2) the consequent Y chromosome transmission disadvantage favored X‐Y fusion (“XP”); (3) Xist‐based silencing of Y‐derived (...)
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  12.  10
    Paradox lost: Concerted evolution and centromeric instability.David Haig - 2022 - Bioessays 44 (8):2200023.
    Homologous centromeres compete for segregation to the secondary oocyte nucleus at female meiosis I. Centromeric repeats also compete with each other to populate centromeres in mitotic cells of the germline and have become adapted to use the recombinational machinery present at centromeres to promote their own propagation. Repeats are not needed at centromeres, rather centromeres appear to be hospitable habitats for the colonization and proliferation of repeats. This is probably an indirect consequence of two distinctive features of centromeric DNA. Centromeres (...)
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  13. Caregiving and role conflict distress.Jordan MacKenzie - 2024 - Clinical Ethics 19 (2):136-142.
    When our nearest and dearest experience medical crises, we may need to step into caregiving roles. But in doing so, we may find that our new caregiving relationship is actually in tension with the loving relationship that motivated us towards care. What we owe and are entitled to as friends, spouses, and family members, can be different from what we owe and are entitled to as caregivers. For this reason, caregiving carries with it the risk of a type of moral (...)
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  14. A robust future for conflict of interest".Edward Wasserman - 2010 - In Christopher Meyers (ed.), Journalism ethics: a philosophical approach. New York: Oxford University Press.
     
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  15. The fortieth annual lecture series 1999-2000.Brain Computations & an Inevitable Conflict - 2000 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 31:199-200.
  16.  15
    The influence of role conflict and self-interest on lying in organizations.Steven L. Grover & Chun Hui - 1994 - Journal of Business Ethics 13 (4):295-303.
    The self-interest paradigm predicts that unethical behavior occurs when such behavior benefits the actor. A recent model of lying behavior, however, predicts that lying behavior results from an individual''s inability to meet conflicting role demands. The need to reconcile the self-interest and role conflict theories prompted the present study, which orthogonally manipulated the benefit from lying and the conflicting role demands. A model integrating the two theories predicts the results, which showed that both elements — self benefit and role (...)
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  17.  67
    Conflict monitoring and cognitive control.Matthew M. Botvinick, Todd S. Braver, Deanna M. Barch, Cameron S. Carter & Jonathan D. Cohen - 2001 - Psychological Review 108 (3):624-652.
  18.  6
    When representations conflict with reality: The preschooler's problem with false beliefs and “false” photographs.D. Zaitchik - 1990 - Cognition 35 (1):41-68.
  19.  80
    Democracy and Moral Conflict.Robert B. Talisse - 2009 - Cambridge University Press.
    Why democracy? Most often this question is met with an appeal to some decidedly moral value, such as equality, liberty, dignity or even peace. But in contemporary democratic societies, there is deep disagreement and conflict about the precise nature and relative worth of these values. And when democracy votes, some of those who lose will see the prevailing outcome as not merely disappointing, but morally intolerable. How should citizens react when confronted with a democratic result that they regard as (...)
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  20.  8
    Bilingualism aids conflict resolution: Evidence from the ANT task.Albert Costa, Mireia Hernández & Núria Sebastián-Gallés - 2008 - Cognition 106 (1):59-86.
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  21. Paradox and Paraconsistency: Conflict Resolution in the Abstract Sciences.John Woods - 2002 - New York: Cambridge University Press.
    In a world plagued by disagreement and conflict one might expect that the exact sciences of logic and mathematics would provide a safe harbor. In fact these disciplines are rife with internal divisions between different, often incompatible, systems. Do these disagreements admit of resolution? Can such resolution be achieved without disturbing assumptions that the theorems of logic and mathematics state objective truths about the real world? In this original and historically rich book John Woods explores apparently intractable disagreements in (...)
     
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  22.  16
    Moral conflict and its structure.David O. Brink - 1994 - Philosophical Review 103 (2):215-247.
  23. Faith and Humility: Conflict or Concord?Daniel Howard-Snyder & Daniel J. McKaughan - 2021 - In Mark Alfano, Michael Patrick Lynch & Alessandra Tanesini (eds.), The Routledge Handbook of the Philosophy of Humility. New York, NY: Routledge. pp. 212-224.
    In some circles, faith is said to be one of three theological virtues, along with hope and agape. But not everyone thinks faith is a virtue, theological or otherwise. Indeed, depending on how we understand it, faith may well conflict with the virtues. In this chapter we will focus on the virtue of humility. Does faith conflict with humility, or are they in concord? In what follows, we will do five things. First, we will sketch a theory of (...)
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  24.  80
    Conflict and The Web of Group-Affiliations. Georg Simmel. Translated by Kurt H. Wolff and Reinhard Bendix. Glencoe, Illinois: The Free Press, 1955. Pp. 195. $3.50.H. S. Harris - 1955 - Philosophy of Science 22 (4):327-327.
  25.  13
    Conflict detection, dual processes, and logical intuitions: Some clarifications.Wim De Neys - 2014 - Thinking and Reasoning 20 (2):169-187.
  26.  89
    Interactive Justice: A Proceduralist Approach to Value Conflict in Politics.Emanuela Ceva - 2016 - New York: Routledge.
    Contemporary societies are riddled with moral disputes caused by conflicts between value claims competing for the regulation of matters of public concern. This familiar state of affairs is relevant for one of the most important debates within liberal political thought: should institutions seek to realize justice or peace? Justice-driven philosophers characterize the normative conditions for the resolution of value conflicts through the establishment of a moral consensus on an order of priority between competing value claims. Peace-driven philosophers have concentrated, perhaps (...)
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  27.  17
    Toleration in Political Conflict.Glen Newey - 2013 - Cambridge University Press.
    Political disputes over toleration are endemic, while toleration as a political value seems opposed to those of civic equality, neutrality and sometimes democracy. Toleration in Political Conflict sets out to understand toleration as both politically awkward and indispensable. The book exposes the incoherence of Rawlsian reasonable pluralist justifications of toleration, and shows that toleration cannot be fully reconciled with liberal political values. While raison d'état concerns very often overshadow debates over toleration, these debates – for example about terrorism – (...)
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  28.  15
    Feelings in moral conflict and the hazards of emotional intelligence.David Carr - 2002 - Ethical Theory and Moral Practice 5 (1):3-21.
    From some perspectives, it seems obvious that emotions and feelings must be both reasonable and morally significant: from others, it may seem as obvious that they cannot be. This paper seeks to advance discussion of ethical implications of the currently contested issue of the relationship of reason to feeling and emotion via reflection upon various examples of affectively charged moral dilemma. This discussion also proceeds by way of critical consideration of recent empirical enquiry into these issues in the literature of (...)
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  29. Cooperation, Culture, and Conflict.Kim Sterelny - 2016 - British Journal for the Philosophy of Science 67 (1):31-58.
    In this article I develop a big picture of the evolution of human cooperation, and contrast it to an alternative based on group selection. The crucial claim is that hominin history has seen two major transitions in cooperation, and hence poses two deep puzzles about the origins and stability of cooperation. The first is the transition from great ape social lives to the lives of Pleistocene cooperative foragers; the second is the stability of the social contract through the early Holocene (...)
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  30. Akrasia and conflict in the Nicomachean Ethics.Mehmet Metin Erginel - 2016 - British Journal for the History of Philosophy 24 (4):573-593.
    In Nicomachean Ethics VII, Aristotle offers an account of akrasia that purports to salvage the kernel of truth in the Socratic paradox that people act against what is best only through ignorance. Despite Aristotle’s apparent confidence in having identified the sense in which Socrates was right about akrasia, we are left puzzling over Aristotle’s own account, and the extent to which he agrees with Socrates. The most fundamental interpretive question concerns the sense in which Aristotle takes the akratic to be (...)
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  31.  54
    The evolutionary interplay of intergroup conflict and altruism in humans: A review of parochial altruism theory and prospects for its extension.Hannes Rusch - 2014 - Proceedings of the Royal Society of London B 281 (1794): 20141539.
    Drawing on an idea proposed by Darwin, it has recently been hypothesised that violent intergroup conflict might have played a substantial role in the evolution of human cooperativeness and altruism. The central notion of this argument, dubbed ‘parochial altruism’, is that the two genetic or cultural traits, aggressiveness against out-groups and cooperativeness towards the in-group, including self-sacrificial altruistic behaviour, might have coevolved in humans. This review assesses the explanatory power of current theories of ‘parochial altruism’. After a brief synopsis (...)
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  32.  17
    MNE Strategic Intervention in Violent Conflict: Variations Based on Conflict Characteristics.Kathleen A. Getz & Jennifer Oetzel - 2009 - Journal of Business Ethics 89 (S4):375 - 386.
    Since the end of the Cold War, there has been a substantial increase in the number of intrastate conflicts around the world. During the last two decades, there have been more than 125 violent conflicts resulting in 7 million deaths (Smith, 2003). Given the prevalence of these conflicts, the inability of some governments to resolve them, and the reluctance of multilateral institutions to intervene, multinational enterprises (MNEs) engaged in international ventures may find themselves in situations where they must respond to (...)
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  33. The Relationship between Science and Christianity: Understanding the Conflict Thesis in Lay Christians.Helen De Cruz - forthcoming - In Yujin Nagasawa & Mohammad Saleh Zarepour (eds.), Global Dialogues in the Philosophy of Religion: from Religious Experience to the Afterlife. Oxford: Oxford University Press.
    Excerpt (in lieu of abstract) My aim in this paper is to put the spotlight on the following questions: how do lay Christians understand the relation between science and religion, and what can this tell us about the relationship between science and Christianity in a more academic setting? My focus will be on lay Christians in the US, in particular White Evangelicals. I will argue that American lay Christians, as well as American laypeople more generally, view the relationship between science (...)
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  34.  7
    Virtues in conflict: tradition and the Korean woman today.Martina Deuchler, Sandra Mattielli & Royal Asiatic Society of Great Britain and Ireland - 1983 - Published for the Royal Asiatic Society, Korea Branch by the Samhwa Pub. Co.
  35.  7
    Conflict-based search for optimal multi-agent pathfinding.Guni Sharon, Roni Stern, Ariel Felner & Nathan R. Sturtevant - 2015 - Artificial Intelligence 219 (C):40-66.
  36.  29
    COVID-19, Moral Conflict, Distress, and Dying Alone.Lisa K. Anderson-Shaw & Fred A. Zar - 2020 - Journal of Bioethical Inquiry 17 (4):777-782.
    COVID-19 has truly affected most of the world over the past many months, perhaps more than any other event in recent history. In the wake of this pandemic are patients, family members, and various types of care providers, all of whom share different levels of moral distress. Moral conflict occurs in disputes when individuals or groups have differences over, or are unable to translate to each other, deeply held beliefs, knowledge, and values. Such conflicts can seriously affect healthcare providers (...)
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  37.  16
    Task conflict and proactive control: A computational theory of the Stroop task.Eyal Kalanthroff, Eddy J. Davelaar, Avishai Henik, Liat Goldfarb & Marius Usher - 2018 - Psychological Review 125 (1):59-82.
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  38.  14
    Moral conflict and political consensus.Amy Gutmann & Dennis Thompson - 1990 - Ethics 101 (1):64-88.
  39.  30
    Ethical conflict in critical care nursing: Correlation between exposure and types.A. Falco-Pegueroles, T. Lluch-Canut, J. Roldan-Merino, J. Goberna-Tricas & J. Guardia-Olmos - 2015 - Nursing Ethics 22 (5):594-607.
  40.  31
    A conflict between finite additivity and avoiding dutch book.Teddy Seidenfeld & Mark J. Schervish - 1983 - Philosophy of Science 50 (3):398-412.
    For Savage (1954) as for de Finetti (1974), the existence of subjective (personal) probability is a consequence of the normative theory of preference. (De Finetti achieves the reduction of belief to desire with his generalized Dutch-Book argument for Previsions.) Both Savage and de Finetti rebel against legislating countable additivity for subjective probability. They require merely that probability be finitely additive. Simultaneously, they insist that their theories of preference are weak, accommodating all but self-defeating desires. In this paper we dispute these (...)
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  41. Subliminal unconscious conflict alpha power inhibits supraliminal conscious symptom experience.Howard Shevrin, Michael Snodgrass, Linda A. W. Brakel, Ramesh Kushwaha, Natalia L. Kalaida & Ariane Bazan - 2013 - Frontiers in Human Neuroscience 7.
    Our approach is based on a tri-partite method of integrating psychodynamic hypotheses, cognitive subliminal processes, and psychophysiological alpha power measures. We present ten social phobic subjects with three individually selected groups of words representing unconscious conflict, conscious symptom experience, and Osgood Semantic negative valence words used as a control word group. The unconscious conflict and conscious symptom words, presented subliminally and supraliminally, act as primes preceding the conscious symptom and control words presented as supraliminal targets. With alpha power (...)
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  42.  12
    Moral differences: truth, justice, and conscience in a world of conflict.Richard W. Miller - 1992 - Princeton University Press.
    In a wide-ranging inquiry Richard W. Miller provides new resources for coping with the most troubling types of moral conflict: disagreements in moral conviction, conflicting interests, and the tension between conscience and desires. Drawing on most fields in philosophy and the social sciences, including his previous work in the philosophy of science, he presents an account of our access to moral truth, and, within this framework, develops a theory of justice and an assessment of the role of morality in (...)
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  43.  48
    Moral Conflict and Prudential Agreement: Michael Moehler’s Minimal Morality.Gerald Gaus - 2019 - Analysis 79 (1):106-115.
    Michael Moehler’s Minimal Morality is a wonderful and important book, from which I have learned a great deal. It reinvigorates rational choice moral theory in the process of confronting what I see as the most important issue in social and moral philosophy today: can those in a deeply morally divided society endorse a common moral framework to structure social cooperation? Is a rational moral order possible under conditions of deep and wide moral diversity? Minimal Morality’s answers are thoughtful and innovative. (...)
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  44.  26
    Conflict and moral change: LGBTQ+ rights education, religion and renegotiation.Nora Hämäläinen - 2021 - Journal of Philosophy of Education 55 (4-5):551-563.
    Journal of Philosophy of Education, EarlyView.
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  45.  14
    Eye Movements, Pupil Dilation, and Conflict Detection in Reasoning: Exploring the Evidence for Intuitive Logic.Zoe A. Purcell, Andrew J. Roberts, Simon J. Handley & Stephanie Howarth - 2023 - Cognitive Science 47 (6):e13293.
    A controversial claim in recent dual process accounts of reasoning is that intuitive processes not only lead to bias but are also sensitive to the logical status of an argument. The intuitive logic hypothesis draws upon evidence that reasoners take longer and are less confident on belief–logic conflict problems, irrespective of whether they give the correct logical response. In this paper, we examine conflict detection under conditions in which participants are asked to either judge the logical validity or (...)
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  46. Conflict of Religion and Science.Yujiro Motora - 1905 - The Monist 15 (3):398-408.
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  47.  65
    Developing the Horizons of the Mind: Relational and Contextual Reasoning and the Resolution of Cognitive Conflict.K. Helmut Reich - 2002 - New York: Cambridge University Press.
    Developing the Horizons of the Mind is a comprehensive book on Relational and Contextual Reasoning, a theory of the human mind which powerfully addresses key areas of human conflict such as the ideological conflict between nations, the conflict in close relationships and the conflict between science and religion. K. Helmut Reich provides a clear and accessible introduction to the fresh RCR way of thinking that encourages people to adopt an inclusive rather than an oppositional approach to (...)
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  48. Multinational Corporations and Local Communities: A Critical Analysis of Conflict.Lisa Calvano - 2008 - Journal of Business Ethics 82 (4):793-805.
    As conflict between multinational corporations and local communities escalates, scholars, executives, activists, and community leaders are calling for companies to become more accountable for the impact of their activities on external stakeholders. In order for business to do so, managers must first understand the causes of conflict with local communities, and communities must understand what courses of action are available to challenge activities they deem harmful to their interests. In this article, I present a framework for examining the (...)
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  49.  37
    Conflict of interest disclosure and the polarisation of scientific communities.Thomas Ploug & Søren Holm - 2015 - Journal of Medical Ethics 41 (4):356-358.
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  50.  16
    Is conflict adaptation an illusion?James R. Schmidt, Wim Notebaert & Eva Van Den Bussche - 2015 - Frontiers in Psychology 6.
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