Delivering high quality genomics-informed care to patients requires accurate test results whose clinical implications are understood. While other actors, including state agencies, professional organizations, and clinicians, are involved, this article focuses on the extent to which the federal agencies that play the most prominent roles — the Centers for Medicare and Medicaid Services enforcing CLIA and the FDA — effectively ensure that these elements are met and concludes by suggesting possible ways to improve their oversight of genomic testing.

Volume 20, Issue 7, July 2020, Page W15-W16.

This essay aims to introduce Giovanni Gentile to scholars of Gramsci studies broadly and Gramsci‐education studies more specifically. The largest part of the essay explores Gentile's academic life, his philosophical agenda, and his political career. Having established a basis for understanding the educational reform Gentile enacted as Mussolini's first Minister of Public Instruction, the essay then surveys the substantial contemporaneous and contemporary English‐language material about it. The essay engages this literature only lightly and briefly in conclusion, for the primary purpose (...) of illustrating the danger of eschewing it. (shrink)

This chapter contains sections titled: Gentile's Academic Life Gentile's Philosophy and Agenda Gentile's Political Career The Riforma Gentile Historicizing Gramsci, Respecting Gentile Notes References.

Thomas Kroedel argues that we can solve a version of the lottery paradox if we identify justified beliefs with permissible beliefs. Since permissions do not agglomerate, we might grant that someone could justifiably believe any ticket in a large and fair lottery is a loser without being permitted to believe that all the tickets will lose. I shall argue that Kroedel’s solution fails. While permissions do not agglomerate, we would have too many permissions if we characterized justified belief as (...) sufficiently probable belief. If we reject the idea that justified beliefs can be characterized as sufficiently probably beliefs, Kroedel’s solution is otiose because the paradox can be dissolved at the outset. (shrink)

In recent work, Thomas Kroedel has proposed a novel solution to the lottery paradox. As he sees it, we are permitted/justified in believing some lottery propositions, but we are not permitted/justified in believing them all. I criticize this proposal on two fronts. First, I think that if we had the right to add some lottery beliefs to our belief set, we would not have any decisive reason to stop adding more. Suggestions to the contrary run into the wrong kind (...) of reason problem. Reflection on the preface paradox suggests as much. Second, while I agree with Kroedel that permissions do not agglomerate, I do not think that this fact can help us solve the lottery paradox. First, I do not think we have any good reason to think that we’re permitted to believe any lottery propositions. Second, I do not see any good reason to think that epistemic permissions do not agglomerate. (shrink)

One of the central debates within contemporary Anglo-American political philosophy concerns how to formulate an egalitarian theory of distributive justice which gives coherent expression to egalitarian convictions and withstands the most powerful anti-egalitarian objections. This book brings together many of the key contributions to that debate by some of the world’s leading political philosophers: Richard Arneson, G.A. Cohen, Ronald Dworkin, Thomas Nagel, Derek Parfit, John Rawls, T.M. Scanlon, and Larry Temkin.

Several authors, including Thomas Nagel and David Gauthier, have defended the view that reasons of self-interest (prudential reasons) are rationally binding. That is, there is always a reason, bearing on the rational advisability, based on one's self-interest and, as a result, a person may act irrationally by knowingly acting against such reasons regardless of the person's desires or values. Both Nagel and Gauthier argue from the rationally mandatory nature of prudential reasons to the conclusion that moral reasons can be (...) rationally mandatory, challenging the neo-Humean position that practical reasons that bear on an agent's rationality are essentially grounded on the agent's subjective, contingent, conative states. I argue, pace Nagel and Gauthier, that prudential reasons are not rationally mandatory--that the rational requirement to act in one's own interest, when it exists, is, as the neo-Humean insists, grounded on one's subjective, contingent, conative states. Prudential reasons are not reasons for every (conceivable) agent--not in the sense that bears on the rational advisability of action. (shrink)

Catherine Malabou, Antonio Negri, John D. Caputo, Bruno Bosteels, Mark C. Taylor, and Slavoj Zizek join seven others--including William Desmond, Katrin Pahl, Adrian Johnston, Edith Wyschogrod, and Thomas A. Lewis--to apply Hegel's thought to twenty-first-century philosophy, politics, and religion. Doing away with claims that the evolution of thought and history is at an end, these thinkers safeguard Hegel's innovations against irrelevance and, importantly, reset the distinction of secular and sacred. These original contributions focus on Hegelian analysis and the transformative (...) value of the philosopher's thought in relation to our current "turn to religion." Malabou develops Hegel's motif of confession in relation to forgiveness; Negri writes of Hegel's philosophy of right; Caputo reaffirms the radical theology made possible by Hegel; and Bosteels critiques fashionable readings of the philosopher and argues against the reducibility of his dialectic. Taylor reclaims Hegel's absolute as a process of infinite restlessness, and Zizek revisits the religious implications of Hegel's concept of letting go. Mirroring the philosopher's own trajectory, these essays progress dialectically through politics, theology, art, literature, philosophy, and science, traversing cutting-edge theoretical discourse and illuminating the ways in which Hegel inhabits them. (shrink)

According to the permissibility solution to the lottery paradox, the paradox can be solved if we conceive of epistemic justification as a species of permissibility. Clayton Littlejohn has objected that the permissibility solution draws on a sufficient condition for permissible belief that has implausible consequences and that the solution conflicts with our lack of knowledge that a given lottery ticket will lose. The paper defends the permissibility solution against Littlejohn's objections.

Clayton Littlejohn claims that the permissibility solution to the lottery paradox requires an implausible principle in order to explain why epistemic permissions don't agglomerate. This paper argues that an uncontentious principle suffices to explain this. It also discusses another objection of Littlejohn's, according to which we’re not permitted to believe lottery propositions because we know that we’re not in a position to know them.

This groundbreaking volume highlights the contemporary relevance of Jacques Lacan (1901-1981), whose linguistic reworking of Freudian analysis radicalized both psychoanalysis and its approach to theology. Part I: Lacan, Religion, and Others explores the application of Lacan's thought to the phenomena of religion. Part II: Theology and the Other Lacan explores and develops theology in light of Lacan. In both cases, a central place is given to Lacan's exposition of the real, thereby reflecting the impact of his later work. Contributors include (...) some of the most renowned readers and influential academics in their respective fields: Tina Beattie, Lorenzo Chiesa, Clayton Crockett, Creston Davis, Adrian Johnston, Katerina Kolozova, Thomas Lynch, Marcus Pound, Carl Raschke, Kenneth Reinhard, Mario D'Amato, Noelle Vahanian, and Slavoj Žižek. Topics traverse culture, art, philosophy, and politics, as well as providing critical exegesis of Lacan's most gnomic utterances on theology, including "The Triumph of Religion."--Back cover. (shrink)

Traditional theistic proofs are often understood as evidence intended to compel belief in a divinity. John Clayton explores the surprisingly varied applications of such proofs in the work of philosophers and theologians from several periods and traditions, thinkers as varied as Ramanuja, al-Ghazali, Anselm, and Jefferson. He shows how the gradual disembedding of theistic proofs from their diverse and local religious contexts is concurrent with the development of natural theologies and atheism as social and intellectual options in early modern (...) Europe and America. Clayton offers a fresh reading of the early modern history of philosophy and theology, arguing that awareness of such history, and the local uses of theistic argument, offer important ways of managing religious and cultural difference in the public sphere. He argues for the importance of historically grounded philosophy of religion to the field of religious studies and public debate on religious pluralism and cultural diversity. (shrink)

Description: Since its inception, the discussion surrounding Open Theism has been dominated by polemics. On crucial philosophical issues, Openness proponents have largely been devoted to explicating the underlying framework and logical arguments supporting their perspective against competing theological and philosophical perspectives. As a result, very little constructive work has been done on the interconnections between Open Theism and the natural sciences. Given the central place of sciences in today's world, any perspective that hopes to have a broad impact must necessarily (...) address such disciplines in a sustained and constructive manner. To date such engagements from the Openness perspective have been rare. God in an Open Universe addresses this deficiency. This book demonstrates that Open Theism makes a distinctive and highly fruitful contribution to the conversation and constructive work occurring between philosophy, theology, and the sciences. The various essays explore subjects ranging from physics to prayer, from special relativity to divine providence, from metaphysics to evolution, and from space-time to God. All who work at the intersection of theology and the sciences will benefit greatly from these essays that break new ground in this important conversation. Endorsements: ""These essays present what is, in my view, the most promising development in theological thinking in our time, and they do so in a way that is both scholarly and accessible. The book is a must for anyone interested in Christian faith and in science."" -Keith Ward University of Oxford ""Open theists affirm the same openness of the future that religious believers assume when they pray and almost all humans assume when they act. The open future is intuitive; but can it be rigorously defended? God in an Open Universe shows that it can. Open theism has always been an attractive view of God; now it becomes a philosophically rigorous one as well. -Philip Clayton Claremont School of Theology About the Contributor(s): William Hasker is Profesor Emeritus of Philosophy at Huntington University. He is the author of numerous articles and five books, including The Emergent Self and The Triumph of God Over Evil. Thomas Jay Oord is Professor of Theology and Philosophy at Northwest Nazarene University. He is the author or editor of more than a dozen books, including Defining Love and Creation Made Free. Dean Zimmerman is Professor in the philosophy department at Rutgers, The State University of New Jersey. He is editor or co-editor of several books, including (with Peter van Inwagen) Persons: Human and Divine. (shrink)

American Academy of Pediatrics (AAP) and American College of Medical Genetics (ACMG) recently provided two recommendations about predictive genetic testing of children. The Clinical Sequencing Exploratory Research Consortium's Pediatrics Working Group compared these recommendations, focusing on operational and ethical issues specific to decision making for children. Content analysis of the statements addresses two issues: (1) how these recommendations characterize and analyze locus of decision making, as well as the risks and benefits of testing, and (2) whether the guidelines conflict or (...) come to different but compatible conclusions because they consider different testing scenarios. These statements differ in ethically significant ways. AAP/ACMG analyzes risks and benefits using best interests of the child and recommends that, absent ameliorative interventions available during childhood, clinicians should generally decline to order testing. Parents authorize focused tests. ACMG analyzes risks and benefits using the interests of the child and other family members and recommends that sequencing results be examined for additional variants that can lead to ameliorative interventions, regardless of age, which laboratories should report to clinicians who should contextualize the results. Parents must accept additional analysis. The ethical arguments in these statements appear to be in tension with each other. (shrink)

In addition to treatments of questions of methodology and implications for life and practice, the Handbook includes sections devoted to the major scientific ...

Big Ideas for Little Kids includes everything a teacher, a parent, or a college student needs to teach philosophy to elementary school children from picture books. Written in a clear and accessible style, the book explains why it is important to allow young children access to philosophy during primary-school education. Wartenberg also gives advice on how to construct a "learner-centered" classroom, in which children discuss philosophical issues with one another as they respond to open-ended questions by saying whether they agree (...) or disagree with what others have said. (shrink)

Crockett develops a constructive radical theology from the philosophy of Kant. Reading The Critique of Judgment back into The Critique of Pure Reason, Crockett draws upon the insights of such continental philosophers as Heidegger, Derrida, Lyotard and Deleuze. This book shows how existential notions of self, time and imagination are interrelated in Kantian thinking, and demonstrates their importance for theology. An original theology of the sublime emerges as a connection is made between the Kantian sublime of the Third Critique and (...) the transcendental imagination of the First Critique. (shrink)

The internalism-externalism debate is one of the oldest debates in epistemology. Internalists assert that the justification of our beliefs can only depend on facts internal to us, while externalists insist that justification can depend on additional, for example environmental, factors. Clayton Littlejohn proposes and defends a new strategy for resolving this debate. Focussing on the connections between practical and theoretical reason, he explores the question of whether the priority of the good to the right might be used to defend (...) an epistemological version of consequentialism, and proceeds to formulate a new 'deontological externalist' view. On this view, the justificatory status of a belief depends upon whether it is fit for the purposes of practical reasoning. Only beliefs that meet externalist standards are fit for such a purpose. If we want to understand how a wide range of norms (e.g., moral norms) apply to rational agents regardless of what their evidence or outlook is like, we have to embrace an externalist account of the justification. (shrink)

A questão relacionada ao método, na obra de Michel Foucault, é uma problemática na qual alguns pesquisadores têm se debruçado, tendo em vista a diversidade dos caminhos de pesquisa trilhados ao longo de sua produção intelectual. Nesse sentido, o presente estudo, através de uma discussão teórica, pretende colocar em pauta o conceito de anarqueologia, desenvolvido pelo filósofo francês no curso Do governo dos vivos, de 1980. A hipótese que se pretende desdobrar é a de que o conceito em voga se (...) inscreve em um percurso teórico-metodológico particular, abarcando um encadeamento dos três domínios ou eixos (ser-saber, ser-poder, ser-consigo) da obra de Foucault, viabilizando assim certa reformulação da interpretação foucaultiana acerca do sujeito. (shrink)

There are many different oughts. There is a moral ought, a prudential ought, an epistemic ought, the legal ought, the ought of etiquette, and so on. These oughts can prescribe incompatible actions. What I morally ought to do may be different from what I self-interestedly ought to do. Philosophers have claimed that these conflicts are resolved by an authoritative ought, or by facts about what one ought to do simpliciter or all-things-considered. However, the only coherent notion of an ought simpliciter (...) has preposterous first-order normative commitments. It is more reasonable to reject the ought simpliciter in favor of the form of normative pluralism advocated in (Tiffany 2007). (shrink)

Clayton Crockett and Jeffrey Robbins describe a number of the intellectual developments and movements that preceded and influenced radical theology. They pay special attention to the hermeneutics of suspicion of Feuerbach, Marx, Freud, and Nietzsche; the phenomenology of Husserl, Heidegger, and Merleau-Ponty; and the linguistic structuralism of Saussure. Crockett and Robbins pay close attention to the role of Derrida’s lecture, “Structure, Sign, and Play in the Discourse of the Human Sciences,” in 1966 before moving on to the Death of (...) God movement. They emphasize the way Tillich’s thought was radicalized by G. Vahanian, Altizer, Daly, and others in combination with Tillich’s theology of culture and existential theology and Bonhoeffer’s influence on the early Death of God thinkers. Finally, Crockett and Robbins discuss radical theology’s hybridization with deconstruction in the work of Raschke, Mark C. Taylor, and Winquist and hybridizing RT with deconstruction. (shrink)

Ever since 1942, when Carl Hempel declared that historical events are explained by subsuming them under laws governing the occurrence of similar events, philosophers have debated the validity of explanations based on "covering laws." In _The Logic of Historical Explanation_, Clayton Roberts provides a key to understanding the role of covering laws in historical explanation. He does so by distinguishing between their use at the macro- and micro- levels, a distinction that no other scholar has made. Roberts contends that (...) the positivists were right to believe that covering laws are indispensable in historical explanations but wrong to think that these laws apply to macro-events. Similarly, the humanists were right to declare that historians do not explain the occurrence of macro-events by subsuming them under covering laws but wrong to deny the role of covering laws in tracing the course of events leading to the macro-event. Roberts resolves this debate by showing that, though useless in explaining macro-events, covering laws are indispensable in connecting the steps in an explanatory narrative. He then sets forth the logic of an explanatory narrative, explores the nature of rational explanation, and distinguishes the logic of historical interpretation from the logic of historical explanation. (shrink)

The specific heat of hydrogen gas at low temperatures was first measured in 1912 by Arnold Eucken in Walther Nernst’s laboratory in Berlin, and provided one of the earliest experimental supports for the new quantum theory. Even earlier, Nernst had developed a quantum theory of rotating diatomic gas molecules that figured in the discussions at the first Solvay conference in late 1911. Between 1913 and 1925, Albert Einstein, Paul Ehrenfest, Max Planck, Fritz Reiche, and Erwin Schrödinger, among many others, attempted (...) theoretical descriptions of the rotational specific heat of hydrogen, with only limited success. Quantum theory also was central to the study of molecular spectra, where initially it was more successful. Moreover, the two problems interacted in sometimes surprising ways. Not until 1927, following Werner Heisenberg’s discovery of the behavior of indistinguishable particles in modern quantum mechanics, did American theorist David Dennison find a successful theory of the specific heat of hydrogen. (shrink)

Mark Schroeder has argued that all reasonable forms of inconsistency of attitude consist of having the same attitude type towards a pair of inconsistent contents (A-type inconsistency). We suggest that he is mistaken in this, offering a number of intuitive examples of pairs of distinct attitudes types with consistent contents which are intuitively inconsistent (B-type inconsistency). We further argue that, despite the virtues of Schroeder's elegant A-type expressivist semantics, B-type inconsistency is in many ways the more natural choice in developing (...) an expressivist account of moral discourse. We close by showing how to adapt ordinary formality-based accounts of logicality to define a B-type account of logical inconsistency and distinguish it from both semantic and pragmatic inconsistency. In sum, we provide a roadmap of how to develop a successful B-type expressivism. (shrink)

Could it be right to convict and punish defendants using only statistical evidence? In this paper, I argue that it is not and explain why it would be wrong. This is difficult to do because there is a powerful argument for thinking that we should convict and punish defendants using statistical evidence. It looks as if the relevant cases are cases of decision under risk and it seems we know what we should do in such cases (i.e., maximize expected value). (...) Given some standard assumptions about the values at stake, the case for convicting and punishing using statistical evidence seems solid. In trying to show where this argument goes wrong, I shall argue (against Lockeans, reliabilists, and others) that beliefs supported only by statistical evidence are epistemically defective and (against Enoch, Fisher, and Spectre) that these epistemic considerations should matter to the law. To solve the puzzle about the role of statistical evidence in the law, we need to revise some commonly held assumptions about epistemic value and defend the relevance of epistemology to this practical question. (shrink)

This paper discusses varieties of normative phenomena, ranging from morality, to epistemic justification, to the rules of chess. It canvases a number of distinctions among these different normative phenomena. The most significant distinction is between formal and authoritative normativity. The prior is the normativity exhibited by any standard one can meet or fail to meet. The latter is the sort of normativity associated with phenomena like the "all-things-considered" ought. The paper ends with a brief discussion of reasons for skepticism about (...) authoritative normativity. (shrink)

What is the future of Continental philosophy of religion? These forward-looking essays address the new thinkers and movements that have gained prominence since the generation of Derrida, Deleuze, Foucault, and Levinas and how they will reshape Continental philosophy of religion in the years to come. They look at the ways concepts such as liberation, sovereignty, and post-colonialism have engaged this new generation with political theology and the new pathways of thought that have opened in the wake of speculative realism and (...) recent findings in neuroscience and evolutionary psychology. Readers will discover new directions in this challenging and important area of philosophical inquiry. (shrink)

In this paper, I present a puzzle about epistemic rationality. It seems plausible that it should be rational to believe a proposition if you have sufficient evidential support for it. It seems plausible that it rationality requires you to conform to the categorical requirements of rationality. It also seems plausible that our first-order attitudes ought to mesh with our higher-order attitudes. It seems unfortunate that we cannot accept all three claims about rationality. I will present three ways of trying to (...) resolve this tension and argue that the best way to do this is to reject the idea that strong evidential support is the stuff rationality is made of. In the course of doing this, I shall argue that there is a special class of propositions about the requirements of rationality that we cannot make rational mistakes about and explain how this can be. (shrink)

Qualitative and quantitative research on the impact of medical and health humanities teaching in baccalaureate education is sparse. This paper reviews recent studies of the impact of medical and health humanities coursework in pre-health professions education and describes a pilot study of baccalaureate students who completed semester-long medical humanities courses in the Division of Medical Humanities & Bioethics at the University of Rochester. The study format was an email survey. All participants were current or former baccalaureate students who had taken (...) one or more courses in literature and narrative in medicine, bioethics, history of medicine, and/or visual arts and healthcare during the past four years. The survey gathered numerical data in several areas: demographic information, career plans, self-reported influence of coursework on educational and career plans, and self-reported influence of coursework on intellectual skills and abilities. It also gathered narrative commentary that elaborated on students’ responses to the numerically-based questions. Notable findings from preliminary analysis of the data include higher scores of self-reported impact of the coursework on specific habits of mind and on preparedness for intended career rather than on gaining admission to future educational programs. Discussion of the results focuses on several potential future directions this type of study might take, including multi-center, longitudinal, and sequential approaches. (shrink)

Belief does aim at the truth. When our beliefs do not fit the facts, they cannot do what they are supposed to do, because they cannot provide us with reasons. We cannot plausibly deny that a truth norm is among the norms that govern belief. What we should not say is that the truth norm is the fundamental epistemic norm. In this paper, I shall argue that knowledge is the norm of belief and that the truth norm has a derivative (...) status. Only a knowledge‐first approach to epistemic normativity can explain why epistemic assessment has its inward‐looking focus. (shrink)

The typical epistemology course begins with a discussion of the distinction between justification and knowledge and ends without any discussion of the distinction between justification and excuse. This is unfortunate. If we had a better understanding of the justification-excuse distinction, we would have a better understanding of the intuitions that shape the internalism-externalism debate. My aims in this paper are these. First, I will explain how the kinds of excuses that should interest epistemologists exculpate. Second, I will explain why the (...) intuitions that underwrite the new evil demon argument don't provide support for the internalist claim that justification is just in the head. The positive response that Cohen's example elicits is an indication that the subject should be excused if she violates an epistemic norm, not an indication that no norm has been violated. For just about any conceivable norm we can think of we can imagine situations in which someone violates that norm because they're moved by evidence that misleadingly suggests that they'd conform to it. When that happens, we'll respond positively in just the way we do when we consider Cohen's deceived subjects. When that happens, we cannot say that the subjects' responses were justified because we've stipulated that the subjects' responses contravene the relevant norms. Regardless of whether you think of norms along internalist or externalist lines, you should see that the intuitions that underwrite the new evil demon objection tell us nothing at all about whether a subject conforms to a norm. They tell us nothing about justification. (shrink)

There is much to like about the idea that justification should be understood in terms of normality or normic support (Smith 2016, Goodman and Salow 2018). The view does a nice job explaining why we should think that lottery beliefs differ in justificatory status from mundane perceptual or testimonial beliefs. And it seems to do that in a way that is friendly to a broadly internalist approach to justification. In spite of its attractions, we think that the normic support view (...) faces two serious challenges. The first is that it delivers the wrong result in preface cases. These cases suggest that the view is either too sceptical or too externalist. The second is that the view struggles with certain kinds of Moorean absurdities. It turns out that these problems can easily be avoided. If we think of normality as a condition on *knowledge*, we can characterise justification in terms of its connection to knowledge and thereby avoid the difficulties discussed here. The resulting view does an equally good job explaining why we should think that our perceptual and testimonial beliefs are justified when lottery beliefs cannot be. Thus, it seems that little could be lost and much could be gained by revising the proposal and adopting a view on which it is knowledge, not justification, that depends directly upon normality. (shrink)