Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various models of public involvement in research are being introduced. Yet, the ways in which public involvement should meet governance challenges are not well understood. We conducted a qualitative study with 36 experts and stakeholders using the World Café method to identify key governance challenges and explore how public involvement can (...) meet these challenges. This brief report discusses four cross-cutting themes from the study: the need to move beyond individual consent; issues in benefit and data sharing; the challenge of delineating and understanding publics; and the goal of clarifying justifications for public involvement. The report aims to provide a starting point for making sense of the relationship between public involvement and the governance of population-level biomedical research, showing connections, potential solutions and issues arising at their intersection. We suggest that, in population-level biomedical research, there is a pressing need for a shift away from conventional governance frameworks focused on the individual and towards a focus on collectives, as well as to foreground ethical issues around social justice and develop ways to address cultural diversity, value pluralism and competing stakeholder interests. There are many unresolved questions around how this shift could be realised, but these unresolved questions should form the basis for developing justificatory accounts and frameworks for suitable collective models of public involvement in population-level biomedical research governance. (shrink)

In discussing the authorship of the first suasoria preserved in Cod. Vat. Lat. 3864 I said that an argument against its Sallustian origin had been found in the words ‘paulo ante hoc bellum’ of 4, 1. By this phrase the author marks an interval of twenty-seven years, and I suggested, as had been done before, that perhaps this is hardly the way ‘in which a man still under forty would refer to so long an interval which had ended only four (...) years before he was writing.’ The elasticity of Latin words indicating number and magnitude is familiar, but by the kindness of Dr. Rice Holmes I have been reminded of a place where some of the more interesting examples have been collected. Dr. Postgate, on p. lxxiv of his edition of Lucan VIII., mentions among other Caesarian passages B.C. 3, 106, 1, where the few days concerned in ‘Caesar paucos dies in Asia moratus’ are something like three weeks; and B.G. 3, 20, 1, where ‘paucis ante annis’ dates an event which probably happened either twenty-one or twenty-two years before the time with which the narrative is concerned. To these Dr. Holmes would add Cic. in Cat. 3, 1, 3, and, by way of contrast, Caesar B.C. 3, 25, 1. In the former the ‘eruption’ of Catiline on the night of November 8–9 is described by Cicero on December 3, twenty-four days later, as having occurred ‘paucis ante diebus’: in the latter a period of scarcely three months is ‘multi menses.’. (shrink)

R.I.G Hughes offers the first detailed and accessible analysis of the Hilbert-space models used in quantum theory and explains why they are so successful.

Hughes approaches his subjects, as he later did with pertinent issues of the twentieth-century, with both reason and compassion.This edition includes an elegant ...

This long-awaited book replaces Hughes and Cresswell's two classic studies of modal logic: _An Introduction to Modal Logic_ and _A Companion to Modal Logic_. _A New Introduction to Modal Logic_ is an entirely new work, completely re-written by the authors. They have incorporated all the new developments that have taken place since 1968 in both modal propositional logic and modal predicate logic, without sacrificing tha clarity of exposition and approachability that were essential features of their earlier works. The book (...) takes readers from the most basic systems of modal propositional logic right up to systems of modal predicate with identity. It covers both technical developments such as completeness and incompleteness, and finite and infinite models, and their philosophical applications, especially in the area of modal predicate logic. (shrink)

Near the middle of his first discussion with Lysis, Socrates asks an odd question—he asks if Lysis’ mother lets him play with her loom or touch her woolworking tools (208d1-e2). It is one of many odd questions, of course, but it is odd nonetheless. Odd, and also funny: it is the one of just two comments in the book that makes Lysis laugh. This question, I argue, reveals the profound depth of Socrates’ inquiry about Lysis’ views about himself and his (...) loved ones. Indeed, the challenge is so profound that at first the only response is laughter. One aspect is a challenge to certain ideals of masculinity, and so I briefly discuss Athenian conceptions of gender and masculinity, along with some Platonic questioning of these conceptions. Reading the Lysis through the lens of gender reveals not only the continued relevance of such a lens, but also the intensity of Socrates’ work, which calls into question basic social structures and markers of identity, like gender, in its pursuit of a liberatory turn to philosophy. We gain insight into his challenge to Athenian understanding of masculinity by observing the way that Socrates’ argumentation undermines much of it, and we more fully appreciate Socrates’ arguments if we see that they intend to subvert gendered expectations. The setting of the dialogue, the questions Socrates asks, and the responses from Lysis all reinforce that what is at stake in the text is Lysis’ character, including his masculinity. (shrink)

A general account of modeling in physics is proposed. Modeling is shown to involve three components: denotation, demonstration, and interpretation. Elements of the physical world are denoted by elements of the model; the model possesses an internal dynamic that allows us to demonstrate theoretical conclusions; these in turn need to be interpreted if we are to make predictions. The DDI account can be readily extended in ways that correspond to different aspects of scientific practice.

Normal propositional modal systems This first chapter has two main aims. One is to give a general account of the propositional modal systems that we shall ...

Saul Kripke, in a series of classic writings of the 1960s and 1970s, changed the face of metaphysics and philosophy of language. Christopher Hughes offers a careful exposition and critical analysis of Kripke's central ideas about names, necessity, and identity. He clears up some common misunderstandings of Kripke's views on rigid designation, causality and reference, and the necessary a posteriori and contingent a priori. Through his engagement with Kripke's ideas Hughes makes a significant contribution to ongoing debates on, (...) inter alia, the semantics of natural kind terms, the nature of natural kinds, the essentiality of origin and constitution, the relative merits of 'identitarian' and counterpart-theoretic accounts of modality, and the identity or otherwise of mental types and tokens with physical types and tokens. No specialist knowledge in either the philosophy of language or metaphysics is presupposed; Hughes's book will be valuable for anyone working on the ideas which Kripke made famous in the philosophy world. (shrink)

Hyman (1999, 2006) argues that knowledge is best conceived as a kind of ability: S knows that p iff S can φ for the reason that p. Hyman motivates this thesis by appealing to Gettier cases. I argue that it is counterexampled by a certain kind of Gettier case where the fact that p is a cause of the subject’s belief that p. One can φ for the reason that p even if one does not know that p. So knowledge (...) is not best conceived as an ability of this kind. (shrink)

In the ever-expanding field of nuclear history, studies of ‘nuclear culture’ are becoming increasingly popular. Often situated within national contexts, they typically explore responses to the nuclear condition in the cultural modes of literature, art, music, theatre, film and other media, as well as nuclear imagery more generally. This paper offers a critique of current conceptions of ‘nuclear culture’, and argues that the term has little analytical coherence. It suggests that historians of ‘nuclear culture’ have tended to essentialize the nuclear (...) to the detriment of historical analysis, and that the wide variety of methodological approaches to ‘nuclear culture’ are simultaneously a strength and a more significant weakness, in that they have little shared sense of the meaning of the term, its theoretical underpinnings or its analytical purchase. The paper then offers a study of Ewan MacColl's 1946 playUranium 235, whose career reveals much about the diversity of cultures of the nuclear in post-war Britain. The study moves us away from a single, homogeneous ‘British nuclear culture’ towards a pluralistic critical history of cultural responses to nuclearization. These responses, I conclude, should be seen as collectively constitutive of the nuclear condition rather than as passive reflections of it. (shrink)

[I] Divine Simplicity: God and His Existence Types of Divine Simplicity Of the properties ascribed to God in Aquinas' natural theology, we may call one sort ...

Providing the most thorough coverage available in one volume, this comprehensive, broadly based collection offers a wide variety of selections in four major genres, and also includes a section on film. Each of the five sections contains a detailed critical introduction to each form, brief biographies of the authors, and a clear, concise editorial apparatus. Updated and revised throughout, the new Fourth Edition adds essays by Margaret Mead, Russell Baker, Joan Didion, Annie Dillard, and Alice Walker; fiction by Nathaniel (...) Hawthorne, Ursula K. LeGuin, Anton Chekov, James Joyce, Katherine Mansfield, F. Scott Fitzgerald, William Faulkner, Alice Walker, Louise Erdrich, Donald Barthelme, and James McPherson; poems by John Donne, Robert Browning, Walt Whitman, Edwin Arlington Robinson, e.e. cummings, Langston Hughes, W.H. Auden, Philip Levine, and Louise Gluck; and plays by August Wilson, Marsha Norman, Wendy Wasserstein, and Vaclav Havel. The chapter devoted to film examines the relation of film to literature and gives the complete screenplay for Citizen Kane plus close analysis of a scene from the film. With its innovative structure, comprehensive coverage, and insightful and stimulating presentation of all kinds of literature, this is an anthology readers will turn to again and again. (shrink)

Terminological debates are often circular and unproductive, so it is a pleasure to investigate the terminology of LeRon Shults, who argues with clarity, defines his terms, and offers reasons for preferring one term over another. I would not, however, waste the readers' time if my aim were merely to challenge some of Shults's nomenclature. When one sets out, as does Shults, to intervene in the process of theogonic reproduction, terminological and metaphorical choices matter a great deal insofar as the semiotic (...) tools one deploys carry emotional and affective baggage that can deeply influence the efficacy of the hoped-for intervention. As I argue below, there is much to commend... (shrink)

Dementia affects millions of people throughout the world. Thinking through Dementia offers a critique of the main models used to understand dementia-the biomedical, neuropsychological, and social constructionist. It discusses clinical issues and cases, together with philosophical work that might help us to better understand and treat this illness.

A principal challenge facing the progressive bioethics project is the crafting of a consistent message on biopolitical issues that divide progressives. -/- The regulation of enhancement technologies is one of the issues central to this emerging biopolitics, pitting progressive defenders of enhancement, “technoprogressives,” against progressive critics. This essay [PDF] will argue that technoprogressive biopolitics express the consistent application of the core progressive values of the Enlightenment: the right of individuals to control their own bodies, brains and reproduction according to their (...) own conscience, under democratic states that work for the public good. -/- Insofar as left bioconservatives want to ensure the safety of therapies and their equitable distribution, these concerns can be addressed by thorough and independent regulation and a universal health care system, and a progressive bioethics of enhancement can unite both enthusiasts and skeptics. Insofar as bioconservative concerns are motivated by deeper hostility to the Enlightenment project however, by assertion of pre-modern reverence for human uniqueness for instance, then a common program is unlikely. -/- imageAfter briefly reviewing the political history and contemporary landscape of biopolitical debates about enhancement, the essay outlines three meta-policy contexts that will impact future biopolicy: the pressure to establish a universal, cost-effective health insurance system, the aging of industrial societies, and globalization. Technoprogressive appeals are outlined that can appeal to key constituencies, and build a majority coalition in support of progressive change. Finally, some guiding principles for a technoprogressive approach to biopolicy are offered. (shrink)

The Neglected Argument for the Reality of God is something of a Rorschach test for scholars of Peirce.1 Some see a creative presentation of his mature philosophy of inquiry, while others find evidence that Peirce was unable to free himself of his conservative religious milieu. As the editors of The Essential Peirce collection noted: “Whether this paper is an elaboration of or an offense against pragmatism is an unsettled question.”2 The primary import of the essay, I contend, is not to (...) defend God’s reality but rather to highlight continuities between religion and science. In doing so, Peirce aims to show theologians how they might better do their jobs. My aim in this paper is to take Peirce’s advice seriously and.. (shrink)

Merleau-Ponty’s understanding of ‘passivity’ is a key to his account of perception. For Merleau-Ponty, perception is the way in which we are involved in the world, and it is on perception that the functions of understanding, reason, and reflection ultimately rest. While in his Phenomenology of Perception it is already clear that passive and active are intertwined, from a series of lectures he gave in 1954–5 we learn that inauguration or ‘institution’ arises out of a passivity that is not merely (...) an absence of activity. I show how the thoroughly temporal status of the subject as ‘instituting’ distinguishes it from a certain model of the ‘constituting’ subject. Next, I argue that, to grasp the sense in which Merleau-Ponty intends ‘passivity’, we must recognize its mediating or transitional status. Specifically, I examine terms that arise repeatedly in his analysis of the Freudian account of the unconscious — namely, ‘pivot’ and ‘enjambment’ — to show how they reveal the peculiar status of a passivity that operates through a dialectic focused on its transitional terms rather than on opposing poles. Finally, I suggest the exchange between passivity and institution that Merleau-Ponty has in mind can be illuminated through consideration of late Palaeolithic cave paintings, where the rock itself seems to begin an expression that the artist completes. (shrink)

Originally published in 1965. This is a textbook of modern deductive logic, designed for beginners but leading further into the heart of the subject than most other books of the kind. The fields covered are the Propositional Calculus, the more elementary parts of the Predicate Calculus, and Syllogistic Logic treated from a modern point of view. In each of the systems discussed the main emphases are on Decision Procedures and Axiomatisation, and the material is presented with as much formal rigour (...) as is compatible with clarity of exposition. The techniques used are not only described but given a theoretical justification. Proofs of Consistency, Completeness and Independence are set out in detail. The fundamental characteristics of the various systems studies, and their relations to each other are established by meta-logical proofs, which are used freely in all sections of the book. Exercises are appended to most of the chapters, and answers are provided. (shrink)

The notion of mutual aid, which Peter Kropotkin introduced in the 19th century, goes against the logic of competition as a natural condition, and instead shows how mutual aid is a more important factor to consider for the survival and flourishing of a group. The best cooperation strategies allow organisms to adapt to different types of changes in their environment—and we have witnessed a lot of these changes since the start of the COVID‐19 pandemic. This propensity towards cooperation is not (...) a foreign concept, despite how it seems to be overshadowed by individualism in Western societies. These reflections then lead us to believe it is possible to apply the anarchist philosophical principle of mutual aid to our social organizations, rather than giving priority, again and again, to competition and professional hierarchies, especially in healthcare systems, and particularly in hospitals were the majority of nurses work. For us, anarchist philosophical precepts, including but not limited to mutual aid, can be the key to a more adequate functioning of healthcare institutions. Anarchism can help to imagine the first steps needed to take to gradually move away from ideologies that encourage competition, professional hierarchies, and illegitimate authority. In this paper, we will first explore some anarchist philosophical precepts before turning to mutual aid as it is currently conceptualised, then highlight several concrete ways it is visible in nursing, as well as ways it can be applied in hospitals, and healthcare systems. (shrink)

The paper aims to explain how Paul Ricœur’s phenomenological and hermeneutic approach offers an original theory of the self as self-attestation. Considering useful an approach that combines the psychological uses of the notion of self with a reflection on one’s capacity to design himself/herself as a person, the paper offers a thorough analysis of Ricœur’s work Soi-même comme un autre / Oneself as Another. The main purpose of this analysis is to highlight that, drawing a clear distinction between two forms (...) of identity (la mêmeté/sameness and l’ipséité/selfhood) and proposing a dialectic between the self and the other, Ricœur grounds his theory on a notion of self which includes one’s acceptance of the other. (shrink)

Locke thought that it was impossible for there to be two things of the same kind in the same place at the same time. I offer (what looks to me like) a counterexample to that principle, involving two ships in the same place at the same time. I then consider two ways of explaining away, and one way of denying, the apparent counterexample of Locke's principle, and I argue that none is successful. I conclude that, although the case under discussion (...) does not refute Locke's principle, it constitutes a serious challenge to it. (shrink)

Williamson (2000) appeals to considerations about when it is natural to say that a hypothesis is consistent with one’s evidence in order to motivate the claim that all and only knowledge is evidence. It is argued here that the relevant considerations do not support this claim, and in fact conflict with it.

Dementia is an illness that raises important questions about our own attitudes to illness and aging. It also raises very important issues beyond the bounds of dementia to do with how we think of ourselves as people--fundamental questions about personal identity. Is the person with dementia the same person he or she was before? Is the individual with dementia a person at all? In a striking way, dementia seems to threaten the very existence of the self.LThis book brings together philosophers (...) and practitioners to explore the conceptual issues that arise in connection with this increasingly common illness. Drawing on a variety of philosophers such as Descartes, Lock, Hume, Wittgenstein, the authors explore the nature of personal identity in dementia. They also show how the lives and selfhood of people with dementia can be enhanced by attention to their psychological and spiritual environment. Throughout, the book conveys a strong ethical message, arguing in favor of treating people with dementia with all the dignity they deserve as human beings. The book covers a range of topics, stretching from talk of basic biology to talk of a spiritual understanding of people with dementia. Accessibly written by leading figures in psychiatry and philosophy, the book presents a unique and long overdue examination of an illness that features in so many of our lives. (shrink)

Conservatism is part of the legacy of the pragmatic tradition’s deep respect for the continuity of inquiry. Despite his commitment to open and fallible inquiry, Charles Sanders Peirce remained his entire life a kind of religious conservative, arguing for a community that would be, in Douglas Anderson’s words “conservative in its practice and liberal in its theory.”1 The following argument is largely about Peirce’s career-long struggle to reconcile conservative practice and liberal theory, especially as they impact his philosophy of inquiry. (...) He offers hints at a solution, what I am calling his “hopeful monster,” but remains ambivalent about this strategy, as should we, his contemporary readers. As described below, a... (shrink)

LeRon Shults and Palgrave MacMillan are happy to announce the arrival of Postpartum Theology!Shults has changed his guiding metaphors during the short interval between the publication of Iconoclastic Theology: Gilles Deleuze and the Secretion of Atheism and Theology After the Birth of God. While Iconoclastic Theology emphasized the iconoclastic potential of theology with the help of Deleuze’s well-struck hammer blows, Theology After the Birth of God adopts natal imagery. The gods, Shults argues, were conceived in the human mind, born into (...) the world as a result of human cognitive errors, and continue to be borne in diverse cultures. Prophets who have announced the death of God have little impacted our continued... (shrink)

While scholars of religion have explored Peirce's philosophy of religion and extensively mined his groundbreaking work in semiotics, other aspects of Peirce's religious and theological thought have been largely ignored within religious studies. In particular, Peirce's theory of inquiry offers several potentially important insights that scholars of religion would do well to consider more fully. These insights are best realized through conceiving of religious participation as a form of inquiry, continuous with but importantly different from other forms of human inquiry. (...) By focusing on the dynamics of belief, doubt, and inquiry that pervade all human endeavors, religious participation can be conceptualized as a... (shrink)

John Canaday, The Nuclear Muse: Literature, Physics, and the First Atomic Bombs. Madison: University of Wisconsin Press, 2000. Pp. xviii+310. ISBN 0-299-16854-9. £19.50.Septimus H. Paul, Nuclear Rivals: Anglo-American Atomic Relations 1941–1952. Columbus: Ohio State University Press, 2000. Pp. ix+266. ISBN 0-8142-0852-5. £31.95.Peter Bacon Hales, Atomic Spaces: Living on the Manhattan Project. Urbana and Chicago: University of Illinois Press, 1997. Pp. 448. ISBN 0-252-02296-3. £22.00.A decade after the end of the Cold War, the culture and technology of nuclear weapons had lost (...) much of the overt sense of dread they once inspired. The decline in international tension following the end of the communist regimes of the Soviet bloc produced a massive shift in the ideology of the nuclear in the 1990s. The de-targeting and dismantling of large numbers of nuclear weapons and the demise of the threat of nuclear annihilation created new conditions both for international security and for the writing of nuclear history. With the declassification and release of large quantities of official documentation from the former adversaries, as well as the fiftieth anniversary of the bombings of Hiroshima and Nagasaki in 1995, a burst of histories of various aspects of the nuclear age have appeared over the last ten years, exploring not just the technopolitics, strategy and operational logistics of the Cold War and the arms race, but the cultural history of the nuclear age, its imagery, its architecture, its oppositional politics and its effects on the landscape, national and regional economies and cultures and indeed everyday life. At a time of global economic and political uncertainty and the emergent threat of capricious international terrorism and new nuclear proliferation, the apparent certainties of the Cold War now even evoke a certain nostalgia, and its artefacts and structures are being recast as ‘heritage’. (shrink)

This paper will discuss the origin of the human mind, and the qualitative discontinuity between human and animal cognition. We locate the source of this discontinuity within the language faculty, and thus take the origin of the mind to depend on the origin of the language faculty. We will look at one such proposal put forward by Hauser et al. (Science 298:1569-1579, 2002), which takes the evolution of a Merge trait (recursion) to solely explain the differences between human and animal (...) cognition. We argue that the Merge-only hypothesis fails to account for various aspects of the human mind. Instead we propose that the process of lexicalisation is also unique to humans, and that this process is key to explaining the vast qualitative differences. We will argue that lexicalisation is a process through which concepts are reformatted to be able to take on semantic features and to take part in grammatical relations. These are both necessary conditions for a grammatical mind and the increased ability to express conceptual content. We therefore propose a possible explanans for the discontinuity between humans and animals, namely that merge with lexicalisation (and consequently semantic features and grammatical relations) is a minimal requirement for the human mind. (shrink)