In Sonic Virtuality: Sound as Emergent Perception, authors Mark Grimshaw and Tom Garner introduce a novel theory that positions sound within a framework of virtuality. Arguing against the acoustic or standard definition of sound as a sound wave, the book builds a case for a sonic aggregate as the virtual cloud of potentials created by perceived sound. The authors build on their recent work investigating the nature and perception of sound as used in computer games and virtual environments, and (...) put forward a unique argument that sound is a fundamentally virtual phenomenon.Grimshaw and Garner propose a new, fuller and more complete, definition of sound based on a perceptual view of sound that accounts more fully for cognition, emotion, and the wider environment. The missing facet is the virtuality: the idea that all sound arises from a sonic aggregate made up of actual and virtual sonic phenomena. The latter is a potential that depends upon human cognition and emotion for its realization as sound. This thesis is explored through a number of philosophical, cognitive, and psychological concepts including: issues of space, self, sonosemantics, the uncanny, hyper-realism, affect, Gettier problems, belief, alief, imagination, and sound perception in the absence of sound sensation.Provocative and original, Grimshaw and Garner's ideas have broader implications for our relationship to technology, our increasingly digital lives, and the nature of our being within our supposed realities. Students and academics from philosophy to acoustics and across the broad spectrum of digital humanities will find this accessible book full of challenging concepts and provocative ideas. (shrink)

This book explores the nature and importance of sound in virtual reality. Approaching the subject from a holistic perspective, the book delivers an emergent framework of VR sound. This framework brings together numerous elements that collectively determine the nature of sound in VR; from various aspects of VR technology, to the physiological and psychological complexities of the user, to the wider technological, historical and sociocultural issues. Garner asks, amongst other things: what is the meaning of sound? How have fictional (...) visions of VR shaped our expectations for present technology? How can VR sound hope to evoke the desired responses for such an infinitely heterogeneous user base? This book if for those with an interest in sound and VR, who wish to learn more about the great complexities of the subject and discover the contemporary issues from which future VR will surely advance. (shrink)

A common and driving assumption in agricultural research is that the introduction of research trials, new practices and innovative technologies will result in technology adoption, and will subsequently generate benefits for farmers and other stakeholders. In Lao PDR, the potential benefits of introduced technologies have not been fully realised by beneficiaries. We report on an analysis of a survey of 735 smallholder farmers in Southern Lao PDR who were questioned about factors that influenced their decisions to adopt new technologies. In (...) this study, we have constructed measures or states of adoption which identify key elements of an adoption decision-making nexus. Analysis was conducted to statistically group explanatory factors of adoption. The key explanatory factors represented attributes of the farmer, the factors considered when undertaking production decisions and elements of the agricultural value chain that present as opportunities or constraints. We describe the combination of farmer’s personal attributes, perceptions of the value chain, and the introduction of new technologies by external actors as an “agricultural research value chain”, where agricultural research activities intervene to derive greater benefits for local farmers. A generalised linear model, via Poisson regression analysis on the identified explanatory factors, was applied to explore how they influence adoption measures and we found several significant relationships. (shrink)

We understand regulatory policy problems against the backdrop of existing implementations of a regulatory framework. There are argument schemes for proposing a policy and for criticising a proposal, rooted in a shared understanding that there is an existing regulatory framework which is implemented in social structures in society, yet has problems. The problems with the existing implementations may be attributed either to those implementations or to the constraints imposed by the regulatory framework. In this paper we propose that calls for (...) change of regulatory policy, and case-based and statistical evidence produced in support of policy proposals, are based in model-based problem solving activities. This perspective suggests schemes for a good argument pro or con a policy proposal, while avoiding the problem of backing up claims and evidence on the policy level with a conjectural deep model of the policy domain. (shrink)

Krueger & Funder's (K&F's) diagnosis of social psychology's obsession with bias is correct and accords with similar observations by self-categorization theorists. However, the analysis of causes is incomplete and suggestions for cures are flawed. The primary problem is not imbalance, but a failure to acknowledge that social reality has different forms, depending on one's social and political vantage point in relation to a specific social context.

The Leibniz Center for Law is involved in the project Digitale Uitwisseling Ruimtelijke Plannen [DURP (http://www.vrom.nl/durp); digital exchange of spatial plans] which develops a XML-based digital exchange format for spatial regulations. Involvement in the DURP project offers new possibilities to study a legal area that hasn’t yet been studied to the extent it deserves in the field of Computer Science & Law. We studied and criticised the work of the DURP project and the Dutch Ministry of internal affairs on metadata (...) for regulatory documents, and made an inventory of issues related to legal knowledge representation that it felt were not sufficiently covered by current initiatives in the Geographic Information Systems (GIS) field. This inventory was an input to the DURP standardisation effort. In a second phase of the project we extended the METALex XML schema (cf. Boer et al. 2002; Boer et al. 2003) for ‚regular’ legal sources that we developed in the past for geospatial regulatory information, in order to support exchange of spatial regulations, including the associated geospatial information in the form of maps. We developed a prototype application and demonstrated how the spatial planning information in GML can be combined with XML with only minimal changes, using the Web Ontology Language (OWL). This paper describes our experiences. (shrink)

Research into the neural correlates of consciousness (NCCs) has blossomed, due to the advent of new and increasingly sophisticated brain research tools. Neuroimaging has uncovered a variety of brain processes that relate to conscious perception, obtained in a range of experimental paradigms. But methods such as functional magnetic resonance imaging or electroencephalography do not always afford inference on the functional role these brain processes play in conscious vision. Such empirical NCCs could reflect neural prerequisites, neural consequences, or neural substrates of (...) a conscious experience. Here, we take a closer look at the use of non-invasive brain stimulation (NIBS) techniques in this context. We discuss and review how NIBS methodology can enlighten our understanding of brain mechanisms underlying conscious vision by disentangling the empirical NCCs. (shrink)

Since the late nineteenth century ‘Scientific Philosophy’ has become a label ascribed to many research programs. German theoretical philosophy of the early twentieth century was dominated by three different trends—Phenomenology, Neo-Kantianism, and Logical Empiricism: Each trend claimed to represent the ‘Scientific Philosophy’. In this context it is astonishing that we know almost nothing about the relationships between these schools. It is true, all of them rejected the speculative metaphysics found, for example, in German Idealism, but knowledge about other connections is (...) scarce. Starting with the question what exactly ‘Scientific Philosophy’ means and how these meanings relate to each other, a thorough investigation of the connections between all three trends has yet to take place.The main goal of the conference was, therefore, to better understand the relationships of these schools through their notions of ‘Scientific Philosophy’. In this context the works of Edmund Husserl (for Ph .. (shrink)

Transcranial magnetic stimulation can be used to mask visual stimuli, disrupting visual task performance or preventing visual awareness. While TMS masking studies generally fix stimulation intensity, we hypothesized that varying the intensity of TMS pulses in a masking paradigm might inform several ongoing debates concerning TMS disruption of vision as measured subjectively versus objectively, and pre-stimulus versus post-stimulus TMS masking. We here show that both pre-stimulus TMS pulses and post-stimulus TMS pulses could strongly mask visual stimuli. We found no dissociations (...) between TMS effects on the subjective and objective measures of vision for any masking window or intensity, ruling out the option that TMS intensity levels determine whether dissociations between subjective and objective vision are obtained. For the post-stimulus time window particularly, we suggest that these data provide new constraints for models of vision and visual awareness. Finally, our data are in line with the idea that pre-stimulus masking operates differently from conventional post-stimulus masking. (shrink)

This work presents elements for an alternative operationalization of monitoring and diagnosis of multi-agent systems, developed in the context of compliance checking. In contrast to traditional accounts of model-based diagnosis, and most proposals concerning non-compliance, our method does not consider any commitment towards the individual unit of agency. Identity is considered to be mostly an attribute to assign responsibility, and not as the only referent to a source of intentionality. The proposed method requires as input a set of prototypical agent-roles (...) known to be relevant for the domain, and an observation, i.e. evidence collected by a monitor agent. We elaborate on a concrete example concerning tax frauds in real-estate transactions. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Just about everything today comes with an operating manual--from your computer to your car, from your cell phone to your iPad. Is it possible that Life comes with an operating manual, as well? That's the simple, but powerful premise of Tom Shadyac's inspiring and provocative first book. Written as a series of essays and dialogues, we are invited into a conversation that is both challenging and empowering. The question now is, can we discern what is written inside of this operating (...) manual and garner the courage to live in accordance with its precepts. (shrink)

According to the Behavioral View of consent, consent must be expressed in behavior in order to release someone from a duty. By contrast, the Mental View of consent is that normatively efficacious consent is entirely mental. In previous work, I defended a version of the Behavioral View, according to which normatively efficacious ‘consent always requires public behavior, and this behavior must take the form of communication in the case of high-stakes consent’. In this essay, I respond to two arguments by (...) proponents of the Mental View. First, Larry Alexander, Heidi Hurd and Peter Westen have argued that my view has mistaken implications concerning the culpability of different actors. I counter that my version of the view does not have these implications, as it leaves us free to draw moral and legal distinctions between different offences involving non-consensual behavior. Second, Larry Alexander and Kimberly Ferzan have argued for an analogy between consent and abandonment: on the grounds that the normative power to abandon resides in one’s will, Alexander and Ferzan concludes consent does too. I counter that abandonment requires behavior, and call into question the assumption that the ethics of property have much to teach us about the ethics of sexual consent. (shrink)

Michel Foucault articulated the hypothesis of biopower and biopolitics in the 1970s, and Giorgio Agamben developed this hypothesis in his Homo Sacer: Sovereign Power and Bare Life, published in English in 1998. Since these interventions, biopower and biopolitics have become indispensable as a theoretical point of reference in the humanities and social sciences. Michael Hardt and Antonio Negri argue that in the last thirty years the process of biopower and biopolitical regulation has increased, so much so that today every aspect (...) of social relation is subjected to the operations of this power. This chapter considers the position of biopower in the thought of Foucault and Agamben, and how the two conceive of power and resistance to power. It examines how biopower relates to sovereign power in both philosophers’ work, and specifically how Agamben’s development of Foucault’s thought is radical and offers a markedly different direction to scholarship on biopower and its relationship to sovereign power. Despite the relative age of Foucault’s writings, they continue to offer conceptual and theoretical tools for scholars in ways that Agamben’s theories and work do not. I use the example of the coronavirus pandemic to illustrate the shortcomings in Agamben’s thought. Finally, this chapter draws on recent work by Alexander Weheliye and Achille Mbembé to explore the close relationship between sexuality and race, and to show how both gender and race open up new avenues for exploring biopower and its relationship to sovereignty in the twenty-first century. (shrink)

The first study dedicated to the relationship between Alexander Pope and George Berkeley, this book undertakes a comparative reading of their work on the visual environment, economics and providence, challenging current ideas of the relationship between poetry and philosophy in early eighteenth-century Britain. It shows how Berkeley's idea that the phenomenal world is the language of God, learnt through custom and experience, can help to explain some of Pope's conservative sceptical arguments, and also his virtuoso poetic techniques.

In lieu of an abstract, here is a brief excerpt of the content:February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd Reviews 161 7 In, respectively, PaciWsm in Britain and Semi-Detached Idealists: the British Peace Movement and International Relations (Oxford: Oxford U. P., 2000). 8 See Monk 2: Chap. 13. FUNCTIONS OR PROPOSITIONAL FUNCTIONS? Alexander Paul Bozzo Philosophy / Marquette U. Milwaukee, wi 53233, usa alexander[email protected] Michael Potter and Tom Ricketts, eds. The Cambridge Companion to Frege. Cambridge, uk: (...) Cambridge U. P., 2010. Pp. vii, 630. isbn 978-0-521-62479-4 (pb). £57.00; £21.99 (pb). us$38.99 (pb). February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd 162 Reviews 1 Frege: Philosophy of Mathematics (Cambridge, ma: Harvard U. P., 1991), p. 111. The paragraph contains an expression of Frege’s Context Principle and the need for Hume’s Principle as a criterion of identity in the deWnition of number. 2 There are in fact Wve stated goals. The others are: (iii) to serve as a reference work for students and non-specialists, (iv) to provide a route into the study of Frege historically and to any relevant contemporary concerns in the philosophies of logic, language, mathematics, and mind, and (v) to provide, for new readers, the most convenient detailed guide to Frege currently available. Gottlob Frege is widely recognized as one of the chief progenitors of mathematical logic and philosophy of languagez—zindeed, the importance attributed to Frege’s innovations is such that Michael Dummett, when reXecting on§62 of Frege’s Die Grundlagen der Arithmetik, feels compelled to remark that the paragraph therein is “arguably the most pregnant philosophical paragraph ever written.”1 Whether or not one agrees with Dummett on this point, the magnitude of Frege’s inXuence on the current philosophical landscape is incontestable. Frege revolutionized the then dominant Aristotelian conception of logic, introducing a formal language now recognized as the predicate calculus. Central to this end were Frege’s insights on quantiWcation, the notation that expressed it, the logicist project, and the extension of mathematical notions like function and argument to natural language. The long-awaited Cambridge Companion to Frege is a compendium of Fregean scholarship that rigorously explores these and similar topics; editors Thomas Ricketts and Michael Potter have compiled a comprehensive collection of fourteen essays that individually provide focused appraisals of a number of Frege’s most substantial insights. On the advice of this journal’s editor, I have limited my review to the connections (or rather dissimilarities ) that exist between Frege and Russell, relying exclusively on Peter Hylton ’s contribution to the collection, “Frege and Russell”. Following a brief consideration of the volume as a whole, I move immediately into a detailed explication of Hylton’s analysis. The volume includes among its goals the following two aims: (i) to provide, for advanced students and specialists, a conspectus of recent interpretation of Frege, and (ii) to dispel the intimidation felt by readers who confront a diUcult thinker.2 I single out these ambitions because they most clearly represent the volume’s strengths and shortcomings. Enthusiasts of Frege will not be disappointed by the multitude of rigorously and technically written essays, essays that contribute substantially and originally to the collective understanding of Frege and his work. For instance, Thomas Ricketts provides a thoughtful and thorough analysis—an analysis that moves well beyond mere explication—of Frege’s concept/object distinction, in particular its relevance for Frege’s Context Principle and logicism more generally. Similarly, Richard Heck addresses a number of central yet largely unexplored issues pertaining to the overall signiWcance of February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd Reviews 163 3 I strongly encourage that non-specialists augment The Cambridge Companion to Frege with Joan Weiner’s Frege Explained: from Arithmetic to Analytic Philosophy (Chicago : Open Court, 2004), one of the best available introductory texts on Frege. 4 The essay in fact was available as early as 2005 in Hylton’s Propositions, Functions, and Analysis: Selected Essays on Russell’s Philosophy (New York, ny: Oxford U. P., 2005). The editors of The Cambridge Companion to Frege partially... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd Reviews 161 7 In, respectively, PaciWsm in Britain and Semi-Detached Idealists: the British Peace Movement and International Relations (Oxford: Oxford U. P., 2000). 8 See Monk 2: Chap. 13. FUNCTIONS OR PROPOSITIONAL FUNCTIONS? Alexander Paul Bozzo Philosophy / Marquette U. Milwaukee, wi 53233, usa alexander[email protected] Michael Potter and Tom Ricketts, eds. The Cambridge Companion to Frege. Cambridge, uk: (...) Cambridge U. P., 2010. Pp. vii, 630. isbn 978-0-521-62479-4 (pb). £57.00; £21.99 (pb). us$38.99 (pb). February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd 162 Reviews 1 Frege: Philosophy of Mathematics (Cambridge, ma: Harvard U. P., 1991), p. 111. The paragraph contains an expression of Frege’s Context Principle and the need for Hume’s Principle as a criterion of identity in the deWnition of number. 2 There are in fact Wve stated goals. The others are: (iii) to serve as a reference work for students and non-specialists, (iv) to provide a route into the study of Frege historically and to any relevant contemporary concerns in the philosophies of logic, language, mathematics, and mind, and (v) to provide, for new readers, the most convenient detailed guide to Frege currently available. Gottlob Frege is widely recognized as one of the chief progenitors of mathematical logic and philosophy of languagez—zindeed, the importance attributed to Frege’s innovations is such that Michael Dummett, when reXecting on§62 of Frege’s Die Grundlagen der Arithmetik, feels compelled to remark that the paragraph therein is “arguably the most pregnant philosophical paragraph ever written.”1 Whether or not one agrees with Dummett on this point, the magnitude of Frege’s inXuence on the current philosophical landscape is incontestable. Frege revolutionized the then dominant Aristotelian conception of logic, introducing a formal language now recognized as the predicate calculus. Central to this end were Frege’s insights on quantiWcation, the notation that expressed it, the logicist project, and the extension of mathematical notions like function and argument to natural language. The long-awaited Cambridge Companion to Frege is a compendium of Fregean scholarship that rigorously explores these and similar topics; editors Thomas Ricketts and Michael Potter have compiled a comprehensive collection of fourteen essays that individually provide focused appraisals of a number of Frege’s most substantial insights. On the advice of this journal’s editor, I have limited my review to the connections (or rather dissimilarities ) that exist between Frege and Russell, relying exclusively on Peter Hylton ’s contribution to the collection, “Frege and Russell”. Following a brief consideration of the volume as a whole, I move immediately into a detailed explication of Hylton’s analysis. The volume includes among its goals the following two aims: (i) to provide, for advanced students and specialists, a conspectus of recent interpretation of Frege, and (ii) to dispel the intimidation felt by readers who confront a diUcult thinker.2 I single out these ambitions because they most clearly represent the volume’s strengths and shortcomings. Enthusiasts of Frege will not be disappointed by the multitude of rigorously and technically written essays, essays that contribute substantially and originally to the collective understanding of Frege and his work. For instance, Thomas Ricketts provides a thoughtful and thorough analysis—an analysis that moves well beyond mere explication—of Frege’s concept/object distinction, in particular its relevance for Frege’s Context Principle and logicism more generally. Similarly, Richard Heck addresses a number of central yet largely unexplored issues pertaining to the overall signiWcance of February 19, 2011 (11:48 am) E:\CPBR\RUSSJOUR\TYPE3002\russell 30,2 040 red.wpd Reviews 163 3 I strongly encourage that non-specialists augment The Cambridge Companion to Frege with Joan Weiner’s Frege Explained: from Arithmetic to Analytic Philosophy (Chicago : Open Court, 2004), one of the best available introductory texts on Frege. 4 The essay in fact was available as early as 2005 in Hylton’s Propositions, Functions, and Analysis: Selected Essays on Russell’s Philosophy (New York, ny: Oxford U. P., 2005). The editors of The Cambridge Companion to Frege partially... (shrink)

TABLE OF CONTENTS Introduction: Pragmatists in Venice Alexander Kremer... 5 I. Philosophy and human evolution Persons as Natural Artifacts Joseph Margolis... 8 II. Cultural politics and democracy Is Marx a Pragmatist? Tom Rockmore... 24 The waxing and waning of democracy as a way of life : Some of the economic underpinnings Jane Skinner... 33 Redefining the Meaning of 'Morality': A Chapter in the Cultural Politics of Capitalism Kenneth W. Stikkers... 42 Imperial Irony: Rorty, Richard Henry Pratt and the American (...) Indian Genocide Scott L Pratt... 48 Bruno Latour, American Pragmatism, and the Idea of Non-Human Democracy Leszek Koczanowicz... 59 Beyond culturalism: A Deweyan reading of the expansion of 'Ndrangheta Matteo Santarelli... 66 Philosophy as Cultural Politics in Rorty, Shusterman, And Pragmatism Alexander Kremer... 79 III. Food, Semiotics, Society John Dewey: A Culinary Perspective Dorota Koczanowicz... 88 De-Subjectification in Semiotics: Argumentations, Self-Defense and Signs of Opposing Forces Martin Svantner... 95 IV. Book Reviews Democracy and Consensus: Review Essay of Leszek Koczanowicz's POLITICS OF DIALOGUE John Ryder... 111 Pragmatism Hotel. R. Calcaterra, G. Maddalena & G. Marchetti : lL PRAGMATISMO. DALLE ORIGINI AGLI SVILUPPI CONTEMPORANEl Brunella Antomarini... 117. (shrink)

There is a relationship between time and technology which has been obvious since the classical philosophies of time. Even telling the time necessitates technologies relating to measuring and counting. Technological developments have changed the temporal state of our reality. Key terms such as deceleration, synchronisation, prevention and de-temporalisation point to relevant problem areas in this respect. This yearbook, whose thematic focus is 2021, endeavours to reveal new technological and philosophical perspectives on the temporal conditions in which we think, communicate, work (...) and live. With contributions by Cornelius Borck, Stefan Böschen, Christopher Coenen, Olivier Del Fabbro, Andreas Folkers, Yvonne Förster, Alexander Friedrich, Steve Fuller, Gabriele Gramelsberger, Thilo Hagendorff, Thomas Hilgers, Dirk Hommrich, Erich Hörl, Sebastian Lederle, Janne Mende, Jürgen Meutgens, Carl Mitcham, Oliver Müller, Alfred Nordmann, Tom Poljanšek, Maurice Merleau-Ponty, Ludger Schwarte, Astrid Schwarz, René von Schomberg, René Umlauf, Sarine Waltenspül, Bastian Weiß, Langdon Winner and Yongmou Liu. (shrink)

Das Nichtwissen ist in aller Munde. Von Nichtwissenskulturen in der zweiten oder reflexiven Moderne ist die Rede, von Agnotologie als neuem Forschungszweig, von wicked problems und ihren clumsy solutions. Wo Nichtwissen sich durch Komplexitäts­steigerung unwiderruflich im zu Wissenden einnistet, fordert es als Grenze, Schranke und Kehrseite des Wissens die sogenannte Wissensgesellschaft heraus. Vor allem Risiko­poten­ziale und Gefahren kommen hier in den Blick, von denen wir gerade genug wissen, um Wissensansprüche zu formulieren, die sich womöglich nie einlösen lassen. Das klassisch erkenntnistheoretische (...) Problem: „Was können wir wissen?“ steht heute in einem Spannungsverhältnis zu der wissenspolitischen Frage: „Was müssen wir wissen?“ Was wir wissen müssen, ist einerseits so viel wie nötig, wenn es um Fragen von Sicherheit und Gesundheit geht – andererseits aber so wenig wie möglich, wenn es in Alltag, Wirtschaft oder Wissen­schaft darauf ankommt, Wissen an technische Systeme oder Expertenkulturen zu delegieren. Bezeichnet politisch handlungsorientiertes und wissenschaftliches Nichtwissen zunächst ein Defizit, ist technisches Nichtwissen gleichermaßen erstrebenswert und problematisch. Einige, die Technik für angewandtes Wissen halten, mögen darin eine contradictio in adjecto sehen, manche sich um eine dem technischen Nichtwissen geschuldeten Technik­feindlichkeit sorgen, andere daraus die nötige Demut gegen verstiegene Allmachts­fantasien beziehen, während ihre Gegenspieler von Maschinen träumen, die über den Horizont intellektueller Nachvollziehbarkeit immer weiter hinauseilen. Mit Beiträgen von: Suzana Alpsancar, Lars Bullmann, Marcus Burkhardt, Eoin Carney, Pelle Ehn, Stefan Frisch, Gerhard Gamm, Petra Gehring, Till Greite, Hans Hasse, Andreas Kaminski, Gregor Kanitz, Matthias Koch, Christian Köhler, Johannes Lenhard, Alexandre Métraux, Alfred Nordmann, Tanja Paulitz, Tom Poljanšek, Sandra Pravica, Katrin Solhdju, Werner Sombart, Florian Sprenger, Sebastian Vehlken und Rüdiger Zill. (shrink)

The prediction of protein–protein interactions based on independently obtained structural information for each interacting partner remains an important challenge in computational chemistry. Procedures where hypothetical interaction models (or decoys) are generated, then ranked using a biochemically relevant scoring function have been garnering interest as an avenue for addressing such challenges. The program PatchDock has been shown to produce reasonable decoys for modeling the association between pig alpha-amylase and the VH-domains of camelide antibody raised against it. We designed a biochemically relevant (...) method by which PatchDock decoys could be ranked in order to separate near-native structures from false positives. Several thousand steps of energy minimization were used to simulate induced fit within the otherwise rigid decoys and to rank them. We applied a partial free energy function to rank each of the binding modes, improving discrimination between near-native structures and false positives. Sorting decoys according to strain energy increased the proportion of near-native decoys near the bottom of the ranked list. Additionally, we propose a novel method which utilizes regression analysis for the selection of minimization convergence criteria and provides approximation of the partial free energy function as the number of algorithmic steps approaches infinity. (shrink)

Privacy is something we all want. We seek privacy to prevent others from securing information about us that is immediately embarrassing, and so causes us pain but not material loss. We also value privacy for strategic reasons in order to prevent others from imposing material and perhaps psychic costs upon us. I use the expression “securing information” so that it covers everything from the immediate sensory data that a voyeur acquires to the financial data a rival may acquire about our (...) businesses. In the degenerate case of the Peeping Tom's invasion of our privacy, suffering is caused just by the voyeur's having acquired the information, even if nothing is ever done with it beyond the voyeur's recalling it from time to time. In all other cases, privacy prevents others from imposing costs or harms on us in ways that require that they secure information about us. (shrink)

In Philosophy 51, October 1976, 471–472, Professor Tom Regan takes ud to task for our attack on Kant's theory concerning the moral status of animals. The ground of Regan's criticism is that ‘… it is clear that Kant does not suppose, as… Broadie and Pybus erroneously assume that he does, that the concept of maltreating an animal, on the one hand, and, on the other, the concept of using an animal as a means, are the same or logically equivalent concepts’ (...) . Regan argues that Kant does not say that we should avoid treating animals as a means. Rather, he claims, Kant's view is that we have an indirect duty not to maltreat animals, since in maltreating them we treat, or run the risk of treating, as a mere means rationality in ourselves or in others. (shrink)

This handbook presents a comprehensive introduction to the core areas of philosophy of education combined with an up-to-date selection of the central themes. It includes 95 newly commissioned articles that focus on and advance key arguments; each essay incorporates essential background material serving to clarify the history and logic of the relevant topic, examining the status quo of the discipline with respect to the topic, and discussing the possible futures of the field. The book provides a state-of-the-art overview of philosophy (...) of education, covering a range of topics: Voices from the present and the past deals with 36 major figures that philosophers of education rely on; Schools of thought addresses 14 stances including Eastern, Indigenous, and African philosophies of education as well as religiously inspired philosophies of education such as Jewish and Islamic; Revisiting enduring educational debates scrutinizes 25 issues heavily debated in the past and the present, for example care and justice, democracy, and the curriculum; New areas and developments addresses 17 emerging issues that have garnered considerable attention like neuroscience, videogames, and radicalization. The collection is relevant for lecturers teaching undergraduate and graduate courses in philosophy of education as well as for colleagues in teacher training. Moreover, it helps junior researchers in philosophy of education to situate the problems they are addressing within the wider field of philosophy of education and offers a valuable update for experienced scholars dealing with issues in the sub-discipline. Combined with different conceptions of the purpose of philosophy, it discusses various aspects, using diverse perspectives to do so. Contributing Editors: Section 1: Voices from the Present and the Past: Nuraan Davids Section 2: Schools of Thought: Christiane Thompson and Joris Vlieghe Section 3: Revisiting Enduring Debates: Ann Chinnery, Naomi Hodgson, and Viktor Johansson Section 4: New Areas and Developments: Kai Horsthemke, Dirk Willem Postma, and Claudia Ruitenberg. (shrink)

Understanding the origins of human social cognition is a central challenge in contemporary science. In recent decades, the idea of a ‘Theory of Mind’ (ToM) has emerged as the most popular way of explaining unique features of human social cognition. This default view has been progressively undermined by research on ‘implicit’ ToM, which suggests that relevant precursor abilities may already be present in preverbal human infants and great apes. However, this area of research suffers from conceptual difficulties and empirical limitations, (...) including explanatory circularity, over-intellectualisation, and inconsistent empirical replication. Our article breaks new ground by adapting ‘script theory’ for application to both linguistic and non-linguistic agents. It thereby provides a new theoretical framework able to resolve the aforementioned issues, generate novel predictions, and provide a plausible account of how individuals make sense of the behaviour of others. Script theory is based on the premise that pre-verbal infants and great apes are capable of basic forms of agency-detection and non-mentalistic goal understanding, allowing individuals to form event-schemata that are then used to make sense of the behaviour of others. We show how script theory circumvents fundamental problems created by ToM-based frameworks, explains patterns of inconsistent replication, and offers important novel predictions regarding how humans and other animals understand and predict the behaviour of others. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:An Unconscious Dimension of Thinking, Situations, and La Vida:Reflections on Bethany Henning's Dewey and the Aesthetic UnconsciousGregory Pappasthis book is doing different related and valuable things. First, Bethany Henning explores a neglected dimension of Dewey's thought. In particular, the book inquires into the dimension of the unconscious and tries to develop what she considers an "implicit" "theory of the unconsciousness" or of the "aesthetic unconscious" in Dewey's philosophy. Then, (...) based on all of the above, it provides a diagnosis and possible solution to a problem with philosophers and with American culture.The neglected dimension of Dewey's thought that Henning explores highlights the ways in which Dewey foresaw what feminist thinkers have said, and recent scientific accounts of human life and thinking are confirming: What we "feel" (what is "qualitative," "ineffable," and "noncognitive") is key to how to think and how to live (guidance and meaning). It has therefore been puzzling to me (along with John McDermott, Tom Alexander, Mark Johnson, and a few others) why even Dewey scholarship has to a large extent neglected exploring this aspect of his thought. Frustrated with Bertrand Russell, Dewey says that "Mr. Russell has not been able to follow the distinction I make between the immediately had material of non-cognitively experienced situations and the material of cognition—a distinction without which my view cannot be understood" (LW 14:33; emphasis added).More importantly, by neglecting this insight and these aspects of his thought, we have failed to utilize one of the most important resources to diagnose sociopolitical-moral problems today! This is what I have been trying to do in recent years, and I see Dr. Henning as trying to do the same. She is not just providing a theory of the unconscious for the sake of speculation, but she does so with instrumental intent, in the hope that it will help us better approach a concrete social-cultural problem we suffer in our society, a topic to which I will return. [End Page 84]My reading of Dewey and the Aesthetic Unconscious has provoked a few questions:(a). Is there, in Dewey, a conception of aesthetic and religious experience that can be understood as an "implicit theory of the unconscious"?(b). Even if there is one, do we need one? For what purpose?(c). What would we miss if we were to say what needs to be said and explored by Henning by using different terms/concepts and avoiding the possible misunderstanding and dangers of making reference to "the unconscious"?(d). Would Henning agree that the problematic aversion or repression in American culture that concerns us is more than that of the unconscious, the qualitative, body, and nature that form the focus of her book?(e). Henning agrees that we need more than art and "deep" psychology to ameliorate the problems that concern us. What is this "more"? How?In regard to (b), I can think of one good purpose, which Henning develops in Dewey and the Aesthetic Unconscious: to engage in a dialogue with psychoanalysis and contemporary philosophies that draw from psychoanalysis and feminism (e.g., Kristeva) or, in general, other academics concerned with the same problems. I also wondered as I was reading the book why Henning does not put Carl Jung in dialogue with Dewey as well, just as a matter of curiosity. But I wonder, if we need to develop a "theory of the unconsciousness" or of the "aesthetic unconsciousness" to both make a contribution to the "depth" of lived experience (La Vida) and also deal with the social-cultural problems that concern us.There are dangers with talking about or making reference to "the" unconsciousness or "the" aesthetic unconsciousness and theorizing about them. The problem is that it comes across as a noun, and not as way of participating in La Vida or nature, that is continuous in a significant way with what is more conscious and more cognitive: we are at any time more or less conscious. But Henning seems aware of all of this. She is careful enough to make clear that she is acknowledging continuity, but I confess to "feeling" uncomfortable sometimes with her reference to that... (shrink)

In this paper we discuss how Causal Decision Theory should be modified to handle a class of problematic cases involving deterministic laws. Causal Decision Theory, as it stands, is problematically biased against your endorsing deterministic propositions (for example it tells you to deny Newtonian physics, regardless of how confident you are of its truth). Our response is that this is not a problem for Causal Decision Theory per se, but arises because of the standard method for assessing the truth of (...) certain counterfactuals. The truth of deterministic laws is `modally fragile' on the standard semantics for counterfactuals: if determinism is true and you were to do otherwise, the laws would be different. We provide two ways of avoiding this problem: 1) supplement the standard semantics for counterfactuals with impossible worlds, or 2) introduce rigid designators into the description of problematic decision situations. We argue that both of these approaches are well-motivated and can be readily incorporated into Lewisian Causal Decision Theory. (shrink)

Some of the most important contributions to animal ethics over the past decade or so have come from political, as opposed to moral, philosophers. As such, some have argued that there been a ‘political turn’ in the field. If there has been such a turn, it needs to be shown that there is something which unites these contributions, and which sets them apart from previous work. We find that some of the features which have been claimed to be shared commitments (...) of the turn are contested by key theorists working in the field. We also find that the originality of the turn can be exaggerated, with many of their ideas found in more traditional animal ethics. Nonetheless, we identify one unifying and distinctive feature of these contributions: the focus on justice; and specifically, the exploration of how political institutions, structures and processes might be transformed so as to secure justice for both human and nonhuman animals. (shrink)

I develop an expressivist account of verbal disagreements as practical disagreements over how to use words rather than factual disagreements over what words actually mean. This account enjoys several advantages over others in the literature: it can be implemented in a neo-Stalnakerian possible worlds framework; it accounts for cases where speakers are undecided on how exactly to interpret an expression; it avoids appeals to fraught notions like subject matter, charitable interpretation, and joint-carving; and it naturally extends to an analysis of (...) metalinguistic negotiations. (shrink)

A common objection to the very idea of conceptual engineering is the topic continuity problem: whenever one tries to “reengineer” a concept, one only shifts attention away from one concept to another. Put differently, there is no such thing as conceptual revision: there’s only conceptual replacement. Here, I show that topic continuity is compatible with conceptual replacement. Whether the topic is preserved in an act of conceptual replacement simply depends on what is being replaced (a conceptual tool or a conceptual (...) role) and what the topic under discussion is. Thus, the topic continuity problem only arises from a failure to specify these two things. (shrink)

This is the second part of a two-part series on the logic of hyperlogic, a formal system for regimenting metalogical claims in the object language (even within embedded environments). Part A provided a minimal logic for hyperlogic that is sound and complete over the class of all models. In this part, we extend these completeness results to stronger logics that are sound and complete over restricted classes of models. We also investigate the logic of hyperlogic when the language is enriched (...) with hyperintensional operators such as counterfactual conditionals and belief operators. (shrink)

A supplemental document for "Metalinguistic Gradability".

Multiple states are at risk of becoming uninhabitable due to climate change, forcing their populations to flee. While the 1951 Refugee Convention provides the gold standard of international protection, it is only applied to a limited subset of people fleeing their countries, those who suffer persecution, which most people fleeing climate change cannot establish. While many journalists and non-lawyers freely use the term “climate refugees,” governments, and courts, as well as UNHCR and many refugee experts, have excluded most climate refugees (...) from the Convention as a matter of legal interpretation. In our 2015 paper, “Unable to Return in the 1951 Refugee Convention: Stateless Refugees and Climate Change”, we sought to reopen the debate on “climate refugees” by arguing that some climate refugees qualify under the 1951 Convention as it is currently written (even if they are not persecuted): those who are stateless and are unable to return to their country of origin because climate change has rendered it uninhabitable. Our interpretation, however, has been rejected by Goodwin-Gill and McAdam (2021) and by Foster and Lambert (2019), which explicitly responds to our paper. Here, we address and respond to their arguments, and develop a new supplementary one, drawing on the principle of systemic integration, as enshrined in Article 31(3)(c) of the Vienna Convention on the Law of Treaties. (shrink)

There is an underlying assumption in the social sciences that consciousness and social life are ultimately classical physical/material phenomena. In this ground-breaking book, Alexander Wendt challenges this assumption by proposing that consciousness is, in fact, a macroscopic quantum mechanical phenomenon. In the first half of the book, Wendt justifies the insertion of quantum theory into social scientific debates, introduces social scientists to quantum theory and the philosophical controversy about its interpretation, and then defends the quantum consciousness hypothesis against the (...) orthodox, classical approach to the mind-body problem. In the second half, he develops the implications of this metaphysical perspective for the nature of language and the agent-structure problem in social ontology. Wendt's argument is a revolutionary development which raises fundamental questions about the nature of social life and the work of those who study it. (shrink)