Response to Don Baxter, Don Garrett and Jennifer Marusic regarding my book Imagined Causes: Hume's Conception of Objects; initially delivered at the 2016 Hume Conference in Sydney, Australia as part of the Author Meets Critics session.

Hume and Quine argue that human beings do not have access to general knowledge, that is, to general truths . The arguments of these two philosophers are premised on what Jaakko Hintikka has called the atomistic postulate. In the present work, it is shown that Hume and Quine in fact sanction an extreme version of this postulate, according to which even items of particular knowledge are not directly accessible in so far as they are relational. For according to their fully (...) realized systems, human beings do not initially perceive any relations, or similar epistemological elements that can associate or combine terms on which a relational or general knowledge claim may be based. Nor, likewise, do human beings perceive the relations or the associations themselves as separate entities. ;In Chapters 1 and 2, respectively, it is shown precisely why Hume and Quine deny that human beings initially perceive either such associative elements or associations in general. Concomitantly, it is made clear why Hume's and Quine's respective epistemologies preclude human beings from initially apprehending not only general knowledge, but particular relational knowledge as well. But this is not to say that Hume and Quine do not think we can eventually acquire such associative elements and correspondingly, knowledge. Rather, Hume and Quine do provide an account of knowledge, but one that holds all relational and connective elements to be constructed by the human mind. In Hume's case, they are constructed by the imagination. In Quine's case, we are never told quite how this construction occurs, although the evidence suggests that Quine implicitly relies on a faculty similar to Hume's imagination. ;In the final chapter of this thesis, it is argued that both Hume and Quine must be read as philosophers who justify knowledge by reducing its possibility to a psychological faculty of construction, as well as to a few concepts of intuitively grasped relations. By way of conclusion, it is shown that this makes Quine's naturalism the psychological heir to Carnap's Aufbau. (shrink)

Hume’s understanding of the external world, particularly, his conception of objects, or what he occasionally refers to as “bodies,” is the subject of much dispute. Are objects mind-independent? Or, are they just what we see, feel, smell, taste, or touch? In other words, are objects just sense data? Or, are they ideas about sense data? Or, are objects, somehow, mind-independent, but we have ideas of them, and we receive sense data from them? In this paper, I provide some answers to (...) these questions—by way of distinguishing between the vulgar position, the philosophical position, and Hume’s position. (shrink)

An overview of Quine's understanding of the analytic/synthetic distinction, especially as it is conveyed in his paper, "The Two Dogmas of Empiricism.".

I argue that Quine’s rejection of Carnap’s “radical” (FLPV; TDE 39) and “phenomenalistic” (FSS 15-16) reductionism—as it is manifest in the Aufbau—may be understood in terms of a broader historical context. In particular, it may be understood as a rejection of a contemporary variant of the second horn of Meno’s Paradox. As a result, Quine’s motivation to adopt naturalism may be understood independently of his pragmatic concerns. According to Quine, it was simply unreasonable (i.e. paradoxical) to adopt a Carnapian phenomenalistic/mentalistic (...) (non-naturalistic) approach to epistemology. Armed with what could only be his invigorated faith in the naturalistic method, he was then, as I see it, equipped to break what we may characterize as the physicalistic version of the naturalistic circle. This is a repudiation that, I show, entails his rejection of “attenuated” (FLPV; TDE 41) reductionism and concomitantly, his rejection of “analyticity,” if not “certainty” altogether. As a result, Quine could simultaneously dismiss what we may characterize as the Humean version of the naturalistic circle. Meanwhile, the practicality of an admittedly fallible science could be unashamedly embraced, although not just for the sake of its practicality—as Quine himself seems to misleadingly indicate throughout his work—but instead, as just noted, to avoid the seemingly Platonic paradox of Aufbauian reductionism. (shrink)

This book provides the first comprehensive account of Hume’s conception of objects in Book I of the Treatise. What, according to Hume, are objects? Ideas? Impressions? Mind-independent objects? All three? None of the above? Through a close textual analysis, I show that Hume thought that objects are imagined ideas. However, I argue that he struggled with two accounts of how and when we imagine such ideas. On the one hand, Hume believed that we always and universally imagine that objects are (...) the causes of our perceptions. On the other hand, he thought that we only imagine such causes when we reach a “philosophical” level of thought. This tension manifests itself in Hume’s account of personal identity; a tension that, I argue, Hume acknowledges in the Appendix to the Treatise. As a result of presenting a detailed account of Hume’s conception of objects, we are forced to accommodate new interpretations of, at least, Hume’s notions of belief, personal identity, justification and causality. (shrink)

In this paper, we see that contrary to most readings of T 1.4.2 in the Treatise ("Of Skepticism with Regard to the Senses"), Hume does not think that objects are sense impressions. This means that Hume's position on objects (whatever that may be) is not to be conflated with the vulgar perspective. Moreover, the vulgar perspective undergoes a marked transition in T 1.4.2, evolving from what we may call vulgar perspective I into vulgar perspective II. This paper presents the first (...) detailed analysis of this evolution, which includes an explanation of T 1.4.2's four-part system. (shrink)

This article shows that in 1.4.2.15-24 of the Treatise of Human Nature, Hume presents his own position on objects, which is to be distinguished from both the vulgar and philosophical conception of objects. Here, Hume argues that objects that are effectively imagined to have a “perfect identity” are imagined due to the constancy and coherence of our perceptions (what we may call ‘level 1 constancy and coherence’). In particular, we imagine that objects cause such perceptions, via what I call ‘indirect (...) causation.’ In virtue of imagining ideas of objects that have a perfect identity, our perceptions seem to be even more constant and coherent (what we may call ‘level 2 constancy and coherence’). Thus, in addition to seeing that Hume is presenting his own position on objects in this section of the Treatise, we see that he is working with a previously unrecognized kind of causation, i.e., indirect causation, and that he has two kinds of constancy and coherence in mind: level 1 and level 2. (shrink)

This paper argues that Husserl’s method is partially driven by an attempt to avoid certain absurdities inherent in Hume’s epistemology. In this limited respect, we may say that Hume opened the door to phenomenology, but as a sacrificial lamb. However, Hume was well aware of his self-defeating position, and perhaps, in some respects, the need for an alternative. Moreover, Hume’s “mistakes” may have incited Husserl’s discovery of the epoche, and thus, transcendental phenomenology.

This paper argues that Husserl’s method is partially motivated by an attempt to avoid certain absurdities inherent in Hume’s epistemology. In this limited respect, we may say that Hume opened the door to phenomenology, but as a sacrificial lamb. However, Hume was well aware of his self-defeating position, and perhaps, in some respects, the need for an alternative. Moreover, Hume’s “mistakes” may have incited Husserl’s discovery of the epoche, and thus, transcendental phenomenology.

This paper argues that Husserl’s method is partially motivated by an attempt to avoid certain absurdities inherent in Hume’s epistemology. In this limited respect, we may say that Hume opened the door to phenomenology, but as a sacrificial lamb. However, Hume was well aware of his self-defeating position, and perhaps, in some respects, the need for an alternative. Moreover, Hume’s “mistakes” may have incited Husserl’s discovery of the epoche, and thus, transcendental phenomenology.

In Book I, III §9 of the Treatise, Hume makes the claim that “[all general] belief arises only from causation” (T 107). Following, he makes the even stronger claim that all general beliefs are to be thought of as beliefs in reality, and thus, all belief in reality is dependent on pre-established beliefs in both specific causal relations and the causal relation in general (T 108). In the first part of this paper, I explain Hume’s motivation behind both claims, while (...) in the second part, I argue that to some extent, Hume is correct; our belief in “reality”—a notion to be defined—is fundamentally dependent on a pre-established belief in the general notion of cause and effect and a cache of specific causal relations. Thus, epistemologically speaking, we must conclude that our notion of “reality” is intrinsically causal (note that this reading has been corrected/augmented in Rocknak 2013). (shrink)

Where does the necessity that seems to accompany causal inferences come from? “Why [do] we conclude that … particular causes must necessarily have such particular effects?” In 1.3.6 of the Treatise, Hume entertains the possibility that this necessity is a function of reason. However, he eventually dismisses this possibility, where this dismissal consists of Hume’s “negative” argument concerning induction. This argument has received, and continues to receive, a tremendous amount of attention. How could causal inferences be justified if they are (...) not justified by reason? If we believe that p causes q, isn’t it reason that allows us to conclude q when we see p with some assurance, i.e. with some necessity? (shrink)

Here we will see that contrary to the party line, Hume’s notion of a relation should be understood, in all cases, as a peculiar non-necessary synthetic relation; unique, but similar in a certain constructive sense to what I characterize as a mathematical notion of synthesis. And, most controversially, I argue that this non-necessary synthetic notion of a relation includes Hume’s arithmetical relations, which have typically been interpreted as either “analytic,” necessary, or both. In this general respect, Hume anticipates Quine’s attack (...) on the analytic/synthetic distinction. (shrink)

According to Husserl, Hume’s empirical method was deeply flawed—like all empiricists, Hume did not, and could not adequately justify his method, much less his findings. Instead, Hume gives us a “circular” and “irrational” “psychological explanation” of “mediate judgments of fact,” i.e. of inductive inferences. Yet Husserl was certain that he could justify both his own method and his own findings with an appeal to the phenomenological, pre-theoretical, pre-naturalistic “epoché”. However, whether or not Husserl’s notion of an epoché is justified, or (...) even viable, is not our focus here. Rather, our issue is with Hume, particularly: How could Hume have responded? In this paper, I show that in Book I of the Treatise, Hume did—however implicitly—appeal to a “pre-theoretical” notion of belief, which meets Husserl’s demands for a pre-theoretical grounding, i.e. a justificatory grounding. And so, his method is, at least in this respect, justified. But this belief is by no means “prenaturalistic.” Rather, it is a function of empirical data. In particular, it is a product of the “constant and coherent” impressions that seem to naturally obtain of experience. As a result, Hume’s method, which, in agreement with Husserl, we may characterize as psychology, does admit of a certain degree of regularity, but an empirical regularity. And according to Hume, contra Husserl’s complaints, this is the best that we can hope for; regularity will have to suffice, not certainty. However, it must be noted up front that this justification is implicit—Hume is not nearly as forthright as he could have been. Thus, making his position more explicit is the task of this paper. I am not presenting my own position, where I offer my own arguments. Instead, I present textual evidence, contextualized with ample explication. It is my hope that by doing so, Hume may more effectively make his case. (shrink)

Is there a distinction between “art” and “craft,” where the former is motivated by something like “genuine” or “authentic” creativity and the latter by, at best, skill and skill alone, and at a worst, a fumbling attempt to fit in with popular modes of expression? In this paper, I suggest that there does seem to be such a distinction. In particular, I attempt to show that genuine creativity, and so, genuine art—in varying respects—is motivated by a certain recognition of what (...) we might understand as the most universal, and perhaps the most important property of all human beings: the brutal fact that our lives are limited; in the end, we all die. To show why I think this is the case, I have divided my paper into three parts. In the first, I briefly explain why we might view mortality as our most pressing issue and concomitantly, why we might understand it to be the driving force behind not only our desire to procreate, but also, to create. In the second part of the paper, I do something that is not strictly “philosophical”—I canvas a number of remarks by poets and writers who, like myself, are convinced that death is our primary muse, but not necessarily in a morbid, or despairing respect—in fact, we see that this is quite the opposite in some cases (c.f. Nabokov, 1966). Why do I do this? Because it seems obvious to me that we should ask the actual artists about what motivates them, rather than putting words into their mouths. In the third and final part of the paper, I offer a brief philosophical explanation of why and how—in light of sections one and two—we might begin to distinguish between genuine art and craft. -/- . (shrink)

Although Symons' recent book, On Dennett (Wadsworth, 2002), provides scientists with ahelpful, general introduction to Dennett'sthought, it presents a skewed version of the history of the philosophy of mind. In particular, the continental tradition is almost entirely ignored, if not glibly dismissed. As aresult, the unwary reader of this book wouldnever realize that Dilthey, Sartre and Husserl,like Dennett, offer a ``middle ground'' between naturalistic realism and naturalistic eliminativism. However, unlike Dennett, the respective positions of Dilthey, Sartre and Husserl are not (...) ontologically indifferent, but instead, present a non-naturalistic form of realism that does not simultaneously invoke Cartesian dualism. (shrink)

By Hume's own account, his most ambitious project, the Treatise on Human Nature, was a notoriously immature undertaking, choked with immutable difficulties.1 Perhaps as a result of this immaturity, and perhaps because, as Kant suggests above, Hume is perpetually misread, his view on objects remains obscured. What are they? Are they ideas? Impressions? Mindindependent objects? All three? None of the above? To date, scholars have not provided a unified, much less exhaustive, answer to these questions. Rather, four somewhat fragmented interpretations (...) have been circulating in the literature. We may characterize them 2 as follows: 1.) The phenomenonalist reading, where objects are... (shrink)

This chapter contains sections titled: Hume's Problem of Induction Hume's Negative Argument concerning Induction.

Tamas Demeter presents a clear and compelling new perspective of Hume’s methodology and conceptual structure in David Hume and the Culture of Scottish Newtonianism. Hume, he argues, is a Newtonian of the Scottish tradition, but not the mechanical kind that is modeled after the Principia. Instead, Hume should be understood as a kind of European Enlightenment “vitalist.” As a result, his work reflects the more organic methodology that defines Newton’s Opticks.

In this book, Schmitt claims that Hume, however implicitly, employs a fully-developed epistemology in the Treatise. In particular, Hume employs a “veritistic” epistemology, i.e. one that is grounded in truth, particularly, true beliefs. In some cases, these true beliefs are “certain,” are “infallible” (78) and are justified, as in the case of knowledge, i.e. demonstrations. In other cases, we acquire these beliefs through a reliable method, i.e. when they are produced by causal proofs. Such beliefs are also “certain” (69, 81) (...) and are (defeasibly) justified. Thus, although demonstrative knowledge and beliefs produced by causal proofs are produced by different psychological processes, and so, admit of specific kinds of “certainty,” they are nevertheless, both certain, and so, they share the same “epistemic status” (68-69). As a result, although it is clear that Hume makes a psychological distinction between demonstrations and causally produced beliefs (proofs) it may be argued that Hume does not make an epistemological distinction between knowledge (demonstrations) and causally produced beliefs (proofs). Thus, in regard to epistemic status, the latter are not necessarily inferior to the former. This has larger implications for Hume’s method; if we can say that he employs a method that invokes knowledge, or at least, beliefs that share the same epistemic status as knowledge, then Hume need not be entirely skeptical about the results of his method. Rather, the possession of true belief is Hume's ultimate goal. (380). (shrink)

Most artists who are familiar with the contemporary art scene—especially the New York City scene—know that “beauty” is not especially hip. Unless, that is, it serves a “deeper” purpose, e.g., it helps to make a conceptual or political point. Danto’s influence, it would seem, pervades and persists (31). But, as Brand points out in her introduction, in the past twenty years or so, the philosophical study of beauty has been making a comeback; she lists over fifty titles that have been (...) written on the subject since the nineties. Brand’s book, Beauty Unlimited, promises to add to the feminist oeuvre on the subject. The book is comprised of twenty essays, with a foreword by Carolyn Korsmeyer and an introduction by Brand. Although the majority of the essays are interdisciplinary, they are primarily written by trained philosophers. Other essays are written by practicing artists and writers, historians, and cultural anthropologists. (shrink)

As Pierre Kerszberg retraces Kant’s critical account of the human being’s confounded, if not tortured, attempts to grasp totality, the reader may occasionally lose sight of the general objectives of the book. In fact, my main criticism of the book concerns Kerszberg’s somewhat cavalier approach to presenting a clear structure of thought. Yet, regardless of the occasional confusion, Critique and Totality is rich with insight and fresh historical perspectives.

In 1986, David Esterly won a competition to carve a replacement of a Grinling Gibbons “wall drop” for Hampten Court Palace, in East Molesey, England. His task was an onerous one: Gibbons invented a style of carving that has been matched by few, and surpassed by still fewer. Esterly is one of the latter few; his technique is superb. -/- The Lost Carving gives us an account of those fateful days at Hampton Court. Interwoven with memories of recreating the Gibbon’s (...) piece, Esterly explains how he got involved with the esoteric field of limewood carving. Although he successfully completed his Ph.D. in English literature, he chose to avoid academia. Gibbons got to him instead, thanks to a chance encounter with one of his carvings in the 1970’s. Ever since, Esterly has struggled to understand, if not reach beyond, Gibbon’s vision and talent. (shrink)

In this ambitious, far-reaching book, Robert Roecklein argues that the philosophical notion of "atomism" has had, and continues to have, a rather crippling effect on philosophy and politics. In particular, Roecklein claims, "atomism" is a metaphysical theory, that, generally speaking, maintains that the ultimate, smallest bits of the universe are not perceivable. Moreover, these bits constitute "indestructible and eternal 'being.'" (xiii) As a result, according to the atomist, "ordinary" experience, particularly, "ordinary" perception -- where we appear to apprehend objects, e.g. (...) tables and chairs -- does not, in fact, access "being." Concomitantly, the "ordinary" person is effectively disenfranchised from most political discussions because, Roecklein claims, political philosophers must have access to being: "Atomism is metaphysics. It leads us back into the domain of 'being.' The domain of 'being' of course is the domain of what exists. Political philosophers above all need to begin with what exists, because political philosophy in truth must begin as opinion" (33). (shrink)

Peter Fosl presents an engaging and historically rich account of Hume's skepticism. For those readers interested in deepening their knowledge and understanding of Pyrrhonian and Academic skepticism, both in regard to their origins and their legacy, I highly recommend it. But I also recommend it for those who would like to better understand Hume's skepticism, although I do think there is some tension in Fosl's reading. Before I discuss this tension, a brief summary of the book is in order. Fosl's (...) primary claim is that Hume's skepticism is a hybrid of Academic and Pyrrhonian skepticism. To show this, Fosl divides the book into two parts. In the first, Fosl presents a detailed account of the ancient and modern versions... (shrink)

Review of Pierre Kerszberg's book Critique and Totality.

Stefanie Rocknak has written an ambitious and challenging book1 in which she argues for a new interpretation of Hume's account of how we come to believe in external objects, and what it is we believe in. I am hampered by the fact that she and I seem to agree on so little. Thus, my criticisms run the danger of simply not seeing what she is up to.A preliminary terminological point: where Rocknak uses the word "object," I will (...) often use the word "body," since I think Hume sometimes uses "object" in a more general sense that includes perceptions.If I understand correctly, Rocknak's Hume argues that we come to believe in bodies through a special kind of causal reasoning. We reason what must exist in order to cause... (shrink)

Stefanie Rocknak's stimulating, challenging, and highly original new book, Imagined Causes: Hume's Conception of Objects, is helpfully summarized on its back cover as follows: This book provides the first comprehensive account of Hume's conception of objects in Book I of A Treatise of Human Nature. What, according to Hume, are objects? Ideas? Impressions? Mind-independent objects? All three? None of the above? Through a close textual analysis, Rocknak shows that Hume thought that objects are imagined ideas. But, she (...) argues, he struggled with two accounts of how and when we imagine such ideas. On the one hand, Hume believes that we always and universally imagine that objects are the causes of our perceptions. On... (shrink)

My paper is concerned with the relation between ought-statements and intentions in Wilfrid Sellars’s philosophy. According to an entrenched view in Sellars scholarship, Sellars considers ought-statements as expressions of we-intentions. The aim of my paper is to question this reading and to propose an alternative. According to this alternative reading of Sellars, ought-statements are metalinguistic statements about the implication relations between intentions. I show that the entrenched understanding faces many unacknowledged problems and generates incompatibilities with Sellars’s commitments about intentions. I (...) argue that the alternative account can help to resolve these problems. A second reason in support of the alternative understanding of Sellars is provided by historical considerations. I argue that my alternative account can be discerned in Sellars’s most developed views about intentions and ought-statements. I also discuss problems and questions which the alternative reading itself faces. (shrink)

The distinction between the manifest and the scientific image of man- in-the-world is widely seen as crucial to Wilfrid Sellars's philosophical work. The present essay agrees with this view. It contends, however, that precisely because the distinction is important, we should not hurry to a quick and superficial understanding of it. The essay identifies several oversimplifications that can be found in the literature on the topic and argues that they are at least partly rooted in too rigid a view of (...) the role that the two-image distinction plays in Sellars's philosophy. It shows that this rigid approach is quite common in the secondary literature, either explicitly or by implication. It then presents a more cautious, flexible approach to the problem of the two images and explains why this approach is fruitful on the basis of textual evidence, along with the overall advantages of interpreting Sellars's thought as a whole. (shrink)

When, in 1735, Alexander Gottlieb Baumgarten added a new discipline to the philosophical system, he not only founded modern aesthetics but also contributed to shaping the modern concept of art or 'fine art'. In The Founding of Aesthetics in the German Enlightenment, Stefanie Buchenau offers a rich analysis and reconstruction of the origins of this new discipline in its wider context of German Enlightenment philosophy. Present-day scholars commonly regard Baumgarten's views as an imperfect prefiguration of Kantian and post-Kantian aesthetics, (...) but Buchenau argues that Baumgarten defended a consistent and original project which must be viewed in the context of the modern debate on the art of invention. Her book offers new perspectives on Kantian aesthetics and beauty in art and science. (shrink)

Wilfrid Sellars is usually read as claiming that only the unobservable, theoretical objects which science would postulate at the ideal end of inquiry are real. Against this, Willem deVries has suggested that we can develop a notion of practical reality in the context of Sellars's philosophy which would pertain primarily to commonsense objects. I use deVries's suggestion as a foil to clarify Sellars's own commitments about the practical. I show that the notion of practical reality is not necessary to secure (...) the ultimate legitimacy of practical concepts. We can retreat to the less committed notion of practical truth. I argue that the notion of practical truth may not be sufficient to ensure that ultimately legitimate practical concepts are commonsense concepts in Sellars's framework. Nevertheless, deVries's suggestion highlights that Sellars's vision of an ultimate conceptual system may have been richer than is often thought. (shrink)

BackgroundEverybody has the right to decide whether to receive specific medical treatment or not and to provide their free, prior and informed consent to do so. As dementia progresses, people with Alzheimer’s dementia (PwAD) can lose their capacity to provide informed consent to complex medical treatment. When the capacity to consent is lost, the autonomy of the affected person can only be guaranteed when an interpretable and valid advance directive exists. Advance directives are not yet common in Germany, and their (...) validity is often questionable. Once the dementia diagnosis has been made, it is assumed to be too late to write an advance directive. One approach used to support the completion of advance directives is ‘Respecting Choices’®—an internationally recognised, evidence-based model of Advance Care Planning (ACP), which, until now, has not been evaluated for the target group of PwAD. This study’s aims include (a) to investigate the proportion of valid advance directives in a memory clinic population of persons with suspected AD, (b) to determine the predictors of valid advance directives, and (c) to examine whether the offer of ACP can increase the proportion of valid advance directives in PwAD.MethodWe intend to recruit at leastN = 250 participants from two memory clinics in 50 consecutive weeks. Of these, the first 25 weeks constitute the baseline phase (no offer of ACP), the following 25 weeks constitute the intervention phase (offer of ACP). The existence and validity of an advance directive will be assessed twice (before and after the memory clinic appointment). Moreover, potential predictors of valid advance directives are assessed.DiscussionThe results of this study will enhance the development of consent procedures for advance directives of PwAD based on the ACP/Respecting Choices (R) approach. Therefore, this project contributes towards increasing the autonomy and inclusion of PwAD and the widespread acceptance of valid advance directives in PwAD.Trial RegistrationDRKS, DRKS00026691, registered 15th of October 2021,https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00026691. (shrink)

Work on a computer program called SMILE + IBP (SMart Index Learner Plus Issue-Based Prediction) bridges case-based reasoning and extracting information from texts. The program addresses a technologically challenging task that is also very relevant from a legal viewpoint: to extract information from textual descriptions of the facts of decided cases and apply that information to predict the outcomes of new cases. The program attempts to automatically classify textual descriptions of the facts of legal problems in terms of Factors, a (...) set of classification concepts that capture stereotypical fact patterns that effect the strength of a legal claim, here trade secret misappropriation. Using these classifications, the program can evaluate and explain predictions about a problem’s outcome given a database of previously classified cases. This paper provides an extended example illustrating both functions, prediction by IBP and text classification by SMILE, and reports empirical evaluations of each. While IBP’s results are quite strong, and SMILE’s much weaker, SMILE + IBP still has some success predicting and explaining the outcomes of case scenarios input as texts. It marks the first time to our knowledge that a program can reason automatically about legal case texts. (shrink)

In this study, Limburgian and Dutch 2,5- to 4-year-olds and adults took part in a word learning experiment. Following the procedure employed by Quam and Swingley (2010) and Singh et al. (2014), participants learned two novel word-object mappings. After training, word recognition was tested in correct pronunciation (CP) trials and mispronunciation (MP) trials featuring a pitch change. Since Limburgian is considered a restricted tone language, we expected that the pitch change would hinder word recognition in Limburgian, but not in non-tonal (...) Dutch listeners. Contrary to our expectations, both Limburgian and Dutch children appeared to be sensitive to pitch changes in newly learned words, indicated by a significant decrease in target fixation in MP trials compared to CP trials. Limburgian and Dutch adults showed very strong naming effects in both trial types. The results are discussed against the background of the influence of the native prosodic system. (shrink)

In all domains of life, transmembrane proteins from the ATP‐binding cassette (ABC) transporter family drive the translocation of diverse substances across lipid bilayers. In pathogenic fungi, the ABC transporters of the pleiotropic drug resistance (PDR) subfamily confer antibiotic resistance and so are of interest as therapeutic targets. They also drive the quest for understanding how ABC transporters can generally accommodate such a wide range of substrates. The Pdr5 transporter from baker's yeast is representative of the PDR group and, ever since (...) its discovery more than 30 years ago, has been the subject of extensive functional analyses. A new perspective of these studies has been recently provided in the framework of the first electron cryo‐microscopy structures of Pdr5, as well as emergent applications of machine learning in the field. Taken together, the old and the new developments have been used to propose a mechanism for the transport process in PDR proteins. This mechanism involves a “flippase” step that moves the substrates from one leaflet of the bilayer to the other, as a central element of cellular efflux. (shrink)

V článku diskutuji východiska knihy Tomáše Hříbka Jaké to je, nebo o čem to je? Cílem článku je ukázat, že přes Hříbkovy sympatie k Dennettovu postmetafyzickému pojetí vědomí lze v jeho výkladu vysledovat tendence k tradičně filosofickému myšlení o vědomí. Soustředím se přitom na Hříbkovu definici fyzikálního a na jeho charakterizaci Dennettova programu jako problematické redukce vědomí pomocí intencionality.

Johanna Charlotte Unzer (1725–1782), born Ziegler, is the author of the first metaphysical treatise intended specifically for women. In the preface of this treatise, published in 1751, she justifies her ‘unhabitual’ enterprise, emphasizing that her intention is not to instruct but only to please her female readership. A closer glance, however, reveals a genuine philosophical intention and an active participation in the debate on popular philosophy and aesthetics in Halle. Challenging an all-too narrow and all-too mathematical conception of practical philosophy, (...) Unzer advocates a dynamic model of philosophy as a love of wisdom, and a philosophy of beauty, poetry, and aesthetics. Fundamentally, these are ancient and mostly Platonic ideas, and among her intellectual circle Unzer stands out as a modern Diotima. But on account of their distinctively modern premises, these ideas likewise take a particularly modern shape, and they illustrate a certain Platonic reversal incipient in Wolffianism itself. (shrink)

This article is about impathy (introversive empathy), understood as the ability to share in and understand one’s own feelings, which is considered a critical psychological construct relevant for the recovery and maintenance of mental health. However, while the ability to empathize with oneself has received considerable attention from the clinical community, this has not been paralleled by the same scientific scrutiny, which was subject to the ability to empathize with others. Impathy has not yet been operationally defined and thus has (...) remained relatively unexplored, both conceptually and empirically. This work describes an operational definition of impathy with four dimensions: Perceiving, Meta-Position, Accepting Attitude, and Understanding. Issues of differentiation from related constructs are discussed and avenues of clinical applicability are explored, suggesting that impathy exists as a distinct human capacity, which can be assessed and which has important clinical implications. The paper closes with future directions, including the assessment of impathy and possible research questions. (shrink)

In "Beyond the Myth of the Myth: A Kantian Theory of Non-Conceptual Content", Robert Hanna argues for a very strong kind of non-conceptualism, and claims that this kind of non-conceptualism originally has been developed by Kant. But according to "Kant's Non-Conceptualism, Rogue Objects and the Gap in the B Deduction", Kant's non-conceptualism poses a serious problem for his argument for the objective validity of the categories, namely the problem that there is a gap in the B Deduction. This gap is (...) that the B Deduction goes through only if conceptualism is true, but Kant is a non-conceptualist. In this paper I argue, contrary to what Hanna claims, that there is not a gap in the B Deduction. (shrink)

Wilfrid Sellars’ philosophical system joins issues that have often been regarded as incompatible or at least in mutual tension. Two of these are his holistic approach to language and knowledge on the one hand and his realism on the other hand. In my paper I first outline this tension and then present a number of steps, including the rejection of semantic relations, picturing and the defense of realism, which can help us to accommodate it. I highlight the payoff of these (...) steps for the question to be solved. In the last part of the paper I detect new and more refined tensions revealed by Sellars’ solution. I identify possible dissonances between his Kantian and his naturalist treatment of causality as well as between his two ways of conceiving of language arguing that these new questions furnish a more interesting approach to our initial problem. (shrink)