As biological and biomedical research increasingly reference the environmental context of the biological entities under study, the need for formalisation and standardisation of environment descriptors is growing. The Environment Ontology (ENVO) is a community-led, open project which seeks to provide an ontology for specifying a wide range of environments relevant to multiple life science disciplines and, through an open participation model, to accommodate the terminological requirements of all those needing to annotate data using ontology classes. This paper summarises ENVO’s motivation, (...) content, structure, adoption, and governance approach. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

For several terms at Cambridge in 1939, Ludwig Wittgenstein lectured on the philosophical foundations of mathematics. A lecture class taught by Wittgenstein, however, hardly resembled a lecture. He sat on a chair in the middle of the room, with some of the class sitting in chairs, some on the floor. He never used notes. He paused frequently, sometimes for several minutes, while he puzzled out a problem. He often asked his listeners questions and reacted to their replies. Many meetings were (...) largely conversation. These lectures were attended by, among others, D. A. T. Gasking, J. N. Findlay, Stephen Toulmin, Alan Turing, G. H. von Wright, R. G. Bosanquet, Norman Malcolm, Rush Rhees, and Yorick Smythies. Notes taken by these last four are the basis for the thirty-one lectures in this book. The lectures covered such topics as the nature of mathematics, the distinctions between mathematical and everyday languages, the truth of mathematical propositions, consistency and contradiction in formal systems, the logicism of Frege and Russell, Platonism, identity, negation, and necessary truth. The mathematical examples used are nearly always elementary. (shrink)

Protagoras, of all the ancient philosophers, has perhaps attracted the most interest in modern times. His saying ‘Man is the measure of all things’ caused Schiller to adopt him as the patron of the Oxford pragmatists, and has generally earned him the title of the first humanist. Yet the exact delineation of his philosophcal position remains a baffling task. Neumann, writing on Die Problematik des ‘Homo-mensura’ Satzes in 1938,2 concludes that no certainty whatever can be reached on the meaning of (...) the dictum, since ‘man’, ‘measure’, and ‘things’ are all ambiguous, nor can we tell which of the three is the predicate. The time is past when it was believed that a man's philosophy could be understood apart from the events of his life and the circumstances of his age: yet in the case of Protagoras the historical method of approach has hardly been attempted, although the impact of environment was perhaps more decisive in the formation of philosophical concepts in the Greek world than anywhere else. The reality about which the Greek philosopher spoke had three aspects: it was either the one universe of physics, or the political unity, or God. For example, the book of Heracleitus Περ φσεως was divided into three chapters or logoi, About the Whole, a political, and a theological. Neither physics nor theology supplies from its own subject-matter the form in which this reality was described. (shrink)

Since archaeology is fundamentally the study of the human past, which is what the word “archaeology” connotes according to its Greek etymology, it is part of the humanities. However, archaeologists work in teams with scientists and employ quantitative techniques and comparative methods of the social sciences; archaeologists are thus an academic hybrid and are pleased to live in the interstices of many disciplines. In this article we review the history of archaeology in the humanities and explore some new directions in (...) archaeological research. We discuss the enduring questions of origins of the antiquity of humanity, religion and art, the first agricultural villages, and the earliest cities, states, and civilizations. We also consider new agendas in archaeology: historical archaeology, landscapes in the past and present, material studies of the present, and how archaeologists are engaged in modern politics. (shrink)

This book uses an incidence approach to look at the economic repercussions of birth defects. The authors investigate eighteen of the most clinically significant birth defects affecting 35,000 newborns each year in our country. Their assessments suggest that the annual cost of these eighteen birth defects, together, is more than eight billion dollars . The authors describe in detail their methodology and data sources while providing thorough accounts of each of the eighteen birth defects. Waitzman, Scheffler, and Romano break new (...) ground by using reports from the California Birth Defects Monitoring Program in order to provide cost estimates. They illustrate to the reader how cost estimates of specific birth defects can be used to justify prevention interventions and strategies. In chapter seven, they provide an important example, showing cost-benefit analysis of a program of folate supplementation of food to prevent neutral tube defects. Contents: List of Tables; Preface; Acknowledgements; Introduction; The Application of Cost-of-Illness Methodology To Birth Defects; The Direct Medical Costs of Birth Defects; Nonmedical Direct Costs of Birth Defects: Developmental Services and Special Education; The Indirect Costs of Birth Defects; Premature Mortality and Heightened Morbidity; An Assessment of Total Costs and Policy Implications; Description of Birth Defects; Description of Major Data Sources; Index. (shrink)

Since the l960s, archaeology has become increasingly taught in universities and practiced on a growing scale by national and local heritage agencies throughout the world. This book addresses the criticisms of postmodernist writers about archaeology's social role, and asserts its intellectual importance and achievements in discovering real facts about the human past. It looks forward to the creation of a truly global consciousness of the origins of human societies and civilizations.

The concepts of freedom and equality lie at the heart of much contemporary political debate. But how, exactly, are these concepts to be understood? And do they really represent desirable political values? Norman begins from the premise that freedom and equality are rooted in human experience, and thus have a real and objective content. He then argues that the attempt to clarify these concepts is therefore not just a matter of idle philosophical speculation, but also a matter of practical (...) politics, for the philosophical conclusions we reach also have important implications for the day-to-day world of political action. Touching on the work of such influential thinkers as Mill, Berlin, Hayek, Nozick, Rawls, and Williams, this book serves as a valuable introduction to the central issues in political philosophy. (shrink)

Spinoza's causal axiom is at the foundation of the Ethics. I motivate, develop and defend a new interpretation that I call the ‘causally restricted interpretation’. This interpretation solves several longstanding puzzles and helps us better understand Spinoza's arguments for some of his most famous doctrines, including his parallelism doctrine and his theory of sense perception. It also undermines a widespread view about the relationship between the three fundamental, undefined notions in Spinoza's metaphysics: causation, conception and inherence.

The problem of Descartes.--The method of Descartes.--The metaphysics of Descartes.--The Cartesian principles in Spinoza and Leibniz.--The Cartesian principles in Locke.--Hume's criticism of the Cartesian principles.--The transition to Kant.

This article presents a critical reevaluation of the thesis—closely associated with H. L. A. Hart, and central to the views of most recent legal philosophers—that the idea of state coercion is not logically essential to the definition of law. The author argues that even laws governing contracts must ultimately be understood as “commands of the sovereign, backed by force.” This follows in part from recognition that the “sovereign,” defined rigorously, at the highest level of abstraction, is that person or entity (...) identified by reference to game theory and the philosophical idea of “convention” as the source of signals with which the subject population has become effectively locked, as a group, into conformity. (shrink)

Schopenhauer is famously abusive toward his philosophical contemporary and rival, Friedrich William Joseph von Schelling. This chapter examines the motivations for Schopenhauer’s immoderate attitude and the substance behind the insults. It looks carefully at both the nature of the insults and substantive critical objections Schopenhauer had to Schelling’s philosophy, both to Schelling’s metaphysical description of the thing-in-itself and Schelling’s epistemic mechanism of intellectual intuition. It concludes that Schopenhauer’s substantive criticism is reasonable and that Schopenhauer does in fact avoid Schelling’s errors: (...) still, the vehemence of the abuse is best perhaps explained by the proximity of their philosophies, not the distance. Indeed, both are developing metaphysics of will with full and conflicted awareness of the Kantian epistemic strictures against metaphysics. In view of this, Schopenhauer is particularly concerned to mark his own project as legitimate by highlighting the manner in which he avoids Schelling’s errors. (shrink)

One of the hallmarks of Kantian philosophy, especially in connection with its characterization of scientific knowledge, is the importance of unity, a theme that is also the driving force behind a good deal of contemporary high energy physics. There are a variety of ways that unity figures in modern science—there is unity of method where the same kinds of mathematical techniques are used in different sciences, like physics and biology; the search for unified theories like the unification of electromagnetism and (...) optics by Maxwell; and, more recently, the project of grand unification or the quest for a theory of everything which involves a reduction of the four fundamental forces under the umbrella of a single theory. In this latter case it is thought that when energies are high enough, the forces, while very different in strength, range and the types of particles on which they act, become one and the same force. The fact that these interactions are known to have many underlying mathematical features in common suggests that they can all be described by a unified field theory. Such a theory describes elementary particles in terms of force fields which further unifies all the interactions by treating particles and interactions in a technically and conceptually similar way. It is this theoretical framework that allows for the prediction that measurements made at a certain energy level will supposedly indicate that there is only one type of force. In other words, not only is there an ontological reduction of the forces themselves but the mathematical framework used to describe the fields associated with these forces facilitates their description in a unified theory. Specific types of symmetries serve an important function in establishing these kinds of unity, not only in the construction of quantum field theories but also in the classification of particles; classifications that can lead to new predictions and new ways of understanding properties like quantum numbers. Hence, in order to address issues about unification and reduction in contemporary physics we must also address the way that symmetries facilitate these processes. (shrink)

Jeffry H. Morrison offers readers the first comprehensive look at the political thought and career of John Witherspoon—a Scottish Presbyterian minister and one of America’s most influential and overlooked founding fathers. Witherspoon was an active member of the Continental Congress and was the only clergyman both to sign the Declaration of Independence and to ratify the federal Constitution. During his tenure as president of the College of New Jersey at Princeton, Witherspoon became a mentor to James Madison and influenced (...) many leaders and thinkers of the founding period. He was uniquely positioned at the crossroads of politics, religion, and education during the crucial first decades of the new republic. Morrison locates Witherspoon in the context of early American political thought and charts the various influences on his thinking. This impressive work of scholarship offers a broad treatment of Witherspoon’s constitutionalism, including his contributions to the mediating institutions of religion and education, and to political institutions from the colonial through the early federal periods. This book will be appreciated by anyone with an interest in American political history and thought and in the relation of religion to American politics. “I have been waiting a long time for such a book on John Witherspoon. This book is not only well-researched, but well-written. The story Morrison tells is quite wonderful.” —_Michael Novak, American Enterprise Institute for Public Policy Research_ _ _ "Dr. John Witherspoon is at once an exceptionally influential figure in Early American history, and a sadly neglected one. Professor Morrison's book fills this gap in American political history brilliantly. It is especially revealing of 18th century views on the interrationships between education, religion, and society. Morrison presents new insights into the Early American understanding of balancing faith, government, and society. It will change our conceptions of this period and provide fresh perspectives on contemporary problems. Everyone interested in the American Founding era is indebted to Morrison for this illuminating book." —_Garrett Ward Sheldon, University of Virginia's College at Wise_ "At last we have a full and learned account, as the title states, of _JOHN WITHERSPOON aND THE FOUNDING OF THE AMERICAN REPUBLIC_. Including discussion of Witherspoon's direct role in the crucial events of 1775-1790 as an advocate of Independence and friend of the Constitution, as a contributor to early American religious and political thought, and most important, as a mentor to James Madison and other Princeton revolutionairies and nation-builders, Morrison reveals Witherspoon's high standing in American religious, educational, and political history. Madison remembered Witherspoon's injunction to his students to 'Lead useful Lives;' he provided an excellent role model." —_Ralph Ketcham, Syracuse University_. (shrink)

This paper provides a description of the ancient sceptic’s way of life that frames skepticism as a pervasive state of mind and character. This state is presented through a causal account of the process through which it is created. Noted as the first rung in this account is the Sceptic Teacher, who, by blending the characteristics of the idea types of Universal Refuter and the Universal Persuader, causes a dispositional tendency in the sceptic student to suspend belief for all propositions (...) p and ~p by presenting equally convincing arguments for each over a range representative of all beliefs. As a result, the sceptic loses many cognitive attitudes completely, and this essay discusses the moral implications of losses of cognitive attitudes of this kind, addressing criticisms of the sceptic’s cognitive tendencies by examining various benefits to such an attitudinal disposition. Such benefits include reduced ataraxia and increased respect for the views of others in that the sceptic grants no special status to his/her own point of view. (shrink)

A powerful work of moral and political philosophy.The idea which I shall present here came to me more or less out of the blue. I was on a train some five years ago, on my way to spend a day at Headingley and I was reading a book about the death camp at Sobibor... The particular, not very appropriate, conjunction involved for me in this train journey... had the effect of fixing my thoughts on one of the more dreadful features (...) of human coexistence, when in the shape of a simple five-word phrase the idea occurred to me. In The Contract of Mutual Indifference, Norman Geras discusses a central aspect of the experience of the Holocaust with a view to exploring its most important contemporary implications. In a bold and powerful synthesis of memorial, literary record, historical reflection and political theory, he focuses on the figure of the bystander -- the bystander to the destruction of the Jews of Europe and the bystander to more recent atrocities -- to consider the moral consequences of looking on without active response at persecution and great suffering. Geras argues that the tragedy of European Jewry, so widely pondered by historians, social scientists, psychologists, theologians and others, has not yet found its proper reflection within political philosophy. Attempting to fill the gap, he adapts an old idea from within that tradition of enquiry, the idea of the social contract, to the task of thinking about the triangular relation between perpetrators, victims and bystanders, and draws a somber conclusion from it. Geras goes on to ask how far this conclusion may be offset by the hypothesis of a universal duty to bring aid. The Contract of Mutual Indifference is an original and challenging work, aimed at the complacent abstraction of much contemporary theory. It is supplemented by three shorter essays on the implications of the Jewish catastrophe for conceptions of human nature and progress and for certain types of Marxist explanation. (shrink)

Complexity theory challenges educational philosophy to reconsider accepted paradigms of teaching, learning and educational research. However, though attractive, not least because of its critique of positivism, its affinity to Dewey and Habermas, and its arguments for openness, diversity, relationships, agency and creativity, the theory is not without its difficulties. These are seen to lie in terms of complexity theory's nature, status, methodology, utility and contribution to the philosophy of education, being a descriptive theory that is easily misunderstood as a prescriptive (...) theory, silent on key issues of values and ethics that educational philosophy should embrace, of questionable internal consistency, and of limited ‘added value’ in educational philosophy. The paper sets out key tenets of complexity theory and argues that, though it is useful for educational philosophy, it requires new conceptual tools and mind‐sets to comprehend fully its significance. (shrink)

The question, What category does the differentia belong to? is a difficult problem in Aristotelian metaphysics. For example, is the differentia of a substance itself a substance, or e.g. a quality? The range of previous interpretations of Aristotle on this point are comprehensively surveyed. Based primarily on evidence in the Categories, this paper argues for an answer to this question.

Of all the major philosophical works, Kant's Critique of Pure Reason is one of the most rewarding, yet one of the most difficult. Norman Kemp Smith's Commentary elucidates not only textural questions and minor issues, but also the central problems which arise, he contends, from the conflicting tendencies of Kant's own thinking. Kemp Smith's Commentary continues to be in demand with Kant scholars, and it is being reissued here with a new introduction by Sebastian Gardner to set it in (...) its contemporary context. (shrink)

Residents are important participants and stakeholders in destination development. Identifying factors that assist in predicting resident pro-environmental behavior (PEB) may contribute to enhanced sustainability. Based on a traditional Chinese culture, this research constructed a model of resident PEB by introducing pro-environmental destination image (PEDI) and Confucianism as the independent and moderating variables, respectively. The structural equation modeling for 402 residents indicated the model had a satisfactory level of predictive power for PEB. The results showed that: (1) PEDI positively affected residents’ (...) environmental identity, pro-environmental attitudes, and PEB; (2) environmental identity and pro-environmental attitudes completely mediated the impact of PEDI on residents’ PEB; and (3) Confucian culture had a positive U-shaped moderating effect in the relationships among these four variables. Overall, these findings advance the understanding of the formation of PEB in Confucian culture and provide theoretical and practical implications for fostering residents’ PEB. (shrink)

This book presents an entirely new answer to the question: “What is fair?” In their radical approach to ethics, Frohlich and Oppenheimer argue that much of the empirical methodology of the natural sciences should be applied to the ethical questions of fairness and justice.

Complexity theory challenges educational philosophy to reconsider accepted paradigms of teaching, learning and educational research. However, though attractive, not least because of its critique of positivism, its affinity to Dewey and Habermas, and its arguments for openness, diversity, relationships, agency and creativity, the theory is not without its difficulties. These are seen to lie in terms of complexity theory's nature, status, methodology, utility and contribution to the philosophy of education, being a descriptive theory that is easily misunderstood as a prescriptive (...) theory, silent on key issues of values and ethics that educational philosophy should embrace, of questionable internal consistency, and of limited ‘added value’ in educational philosophy. The paper sets out key tenets of complexity theory and argues that, though it is useful for educational philosophy, it requires new conceptual tools and mind‐sets to comprehend fully its significance. (shrink)

“Marx did not reject the idea of a human nature. He was right not to do so.” That is the conclusion of this passionate and polemical new work by Norman Geras. In it, he places the sixth of Marx’s Theses on Feuerbach under rigorous scrutiny. He argues that this ambiguous statement—widely cited as evidence that Marx broke with all conceptions of human nature in 1845—must be read in the context of Marx’s work as a whole. His later writings are (...) informed by an idea of a specifically human nature that fulfills both explanatory and normative functions. The belief that Marx’s historical materialism entailed a denial of the conception of human nature is, Geras writes, “an old fixation, which the Althusserian influence in this matter has fed upon … Because this fixation still exists and is misguided, it is still necessary to challenge it.” One hundred years after Marx’s death, this timely essay—combining the strengths of analytical philosophy and classical Marxism—rediscovers a central part of his heritage. (shrink)

A satisfactory contextualist theory of knowledge must provide an account of how knowledge varies across contexts. There are three contextualist proposals for developing such an account. This paper demonstrates that all of them are unacceptable. Contextualists have therefore failed to provide a satisfactory theory of knowledge.

A satisfactory contextualist theory of knowledge must provide an account of how knowledge varies across contexts. There are three contextualist proposals for developing such an account. This paper demonstrates that all of them are unacceptable. Contextualists have therefore failed to provide a satisfactory theory of knowledge.

Unified theory of cognition -- Psychological laws -- Foundations of person cognition -- Functional theory of attitudes -- Attitude integration theories -- Comparisons of attitude theories -- Moral algebra -- Group dynamics -- Cognitive theory of judgment-decision -- General theory -- Experimental methods -- Unified science of psychology.

El ensayo siguiente consiste en una reinterpretación de la obra de Frantz Fanon a partir de la problemática biopolítica iniciada por Michel Foucault. Se analizan los procesos a través de los cuales las vidas de los colonizados se determinan como inhumanas, y se insertan dentro de un "lenguaje de pura violencia", es decir de una red de poderes violentos, soberanos y totalizantes. Fanón va a pensar una puesta en jaque de aquel estado de excepción permanente colonial a partir de la (...) violencia misma, ya que se tratara para él de transformar, sobre la práctica de las luchas, la violencia en ejercicio del descubrimiento de la verdad. In this essay we approach Franz Fanon's work from a biopolitical standpoint as initiated by Michel Foucault. We analyze the processes that lead to the notion of colonized people's life as less than human with a "language of pure violence", that is, within a network of violent powers at the same time sovereign and totalizing. Fanón intends to check that permanent "state of emergency" of the colonies by means of violence itself, since fighting can be transformed from violence alone to the fight for the discovery of truth. (shrink)

Reprint of the original, first published in 1919.

Introduction This book aims at continuing a conversation. It takes for interlocutor a writer who is himself today indefatigable in engaging with the ideas ...