Precision cell signaling activities of reactive electrophilic species (RES) are arguably among the most poorly‐understood means to transmit biological messages. Latest research implicates native RES to be a chemically‐distinct subset of endogenous redox signals that influence cell decision making through non‐enzyme‐assisted modifications of specific proteins. Yet, fundamental questions remain regarding the role of RES as bona fide second messengers. Here, we lay out three sets of criteria we feel need to be met for RES to be considered as true cellular (...) signals that directly mediate information transfer by modifying “first‐responding” sensor proteins. We critically assess the available evidence and define the extent to which each criterion has been fulfilled. Finally, we offer some ideas on the future trajectories of the electrophile signaling field taking inspiration from work that has been done to understand canonical signaling mediators. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:What Emotional Responding Is to Blame It Might Not Be to ResponsibilityR. J. R. Blair (bio)Keywordsblame, responsibility, emotional responses, psychopathyIn this interesting paper, Levy argues that by failing the moral/conventional distinction task (Blair 1995), individuals with psychopathy show a fundamental inability to categorize moral harms and as such their moral responsibility for their actions is reduced. He argues that, although we might still wish to incarcerate such individuals to (...) prevent them inflicting further harm on others, we should be less enthusiastic to blame them for their actions.In many respects, I agree with much of Levy's treatise. I certainly do not regard ascriptions of blame as useful in my own work with this population. I believe that our goal should be to fully understand the nature of their emotional deficit to be able to treat it similarly to other researchers who work to treat other emotional disorders. To me, Levy's argument appears sound.However, I offer three considerations and raise questions within these considerations that might further the debate. First, not all rules involve care-based emotional responses to victims. As Levy notes, this is the origin of the moral/conventional distinction. The problem here is that we do consider someone responsible if they break a conventional transgression. The student talking in class is generally considered blameworthy for this action as long as they knew that the rule of not talking during the lesson applied to that classroom. Yet, there is no victim and no care-based emotional response. Here, the only thing necessary to ascribe blame and responsibility is that the individual knew that a rule exists. Given this holds for conventional transgressions, why must we necessarily make a special case, with respect to responsibility, for moral transgressions?I believe that Levy is fully aware of this concern. He specifically makes reference to moral responsibility and writes that:the kind and degree of wrongness, and therefore blame, which attaches to infringements of the rules [against double parking or line-jumping] is very different, and usually much less significant, than the kind and degree attaching to moral wrongs. For psychopaths, all offences are merely conventional, and therefore—from their point of view—none of them are all that serious.(2007, p. 132)But the danger here is that issues of blame and responsibility may become highly relativistic and hinge on the strength of the emotional reaction. This is a problem because, although we might judge someone as more blameworthy if he intentionally [End Page 149] runs over five people rather than one, do we really consider that there is a distinction in moral responsibility between these two cases? If not, might not responsibility relate to factual knowledge of the existence of the rule against the transgression rather than the emotional response to the transgression?Second, there is considerable debate regarding whether psychopathy represents a taxon or a continuum (e.g., Vasey et al. 2005; Edens et al. 2006). Assuming it does represent a continuum, then we have an additional concern. How little of an emotional response to the transgression reduces one's moral responsibility and blame? Is it only the very reduced (although usually not absent) levels of emotional response that are shown by individuals with psychopathy? Or should we consider moral responsibility and blame proportional to the level of the emotional response? If this latter option is adopted, then what should we do about individuals who show heightened emotional responses, for example, patients with specific anxiety disorders (Rauch, Shin, and Wright 2003)? There are already some data that inhibited children (a developmental precursor to some anxiety disorders; Kagan and Snidman 1999) show heightened conscience development (Asendorpf and Nunner-Winkler 1992). If such children commit moral transgressions, should we regard them as more morally responsible and more blameworthy than regular folks?Third, the issue of intention received little attention in this paper. I have been considered to show a similar lack of attention to intention in the past (Nichols 2002) and, moreover, in some respects the issue was of limited concern given Levy's main goals. However, I mention it because so much of whether we consider someone responsible for their actions and... (shrink)

Aetiological poetry tends to be mature poetry in both a literary and a political sense. Interest in antiquarian lore belongs in general to a poet's middle and later years when youthful and audacious quests for what is avant-garde and anti-establishment have yielded to conservatism and a desire to preserve the past. Propertius and Ovid both turned to aetiological poetry after a long apprenticeship in amatory ‘nugae’ which enabled them, like their predecessor, Callimachus, to embellish their work with a diversity of (...) artistic devices founded on considerable poetic skill and literary experience. With this, a vital ploy to engage the sympathy of a sophisticated audience, went the poise and urbanity with which the aetiological poet found humour in the pose of earnest researcher, in the naivety of primitive cult and in clever literary adaptations. Moreover, dedication to a form of writing essentially nationalist and conservative encouraged a tone of patriotic pride and allusions, even compliments, to the ruling powers. In the light of such considerations we may examine Ovid's account of the ‘Ludi Megalenses’. The ‘Megalensia’ furnished Ovid with a goddess who had enjoyed fame and even notoriety in the pages of Roman literature. In addition to showing a poetic and neoteric interest in the orgiastic elements of her cult and the alien music of her retinue Roman poetry could reflect too the awe and reverence inspired of old by the Great Mother and expressed in the Greek poets, whom Lucretius claimed as his sources in his powerfully beautiful excursus on Cybele worship. Again, Cybele's importance in Rome had been augmented by her Trojan origins, concerning which a canonical Augustan theology had been established by Vergil in the Aeneid. (shrink)

The problems and the history of contacts between distant continents in bygone ages and long before the age of fast and easy travel, have always fascinated both professional scholars and the interested public. Was ancient history really nothing but the history of co-existing and isolated geographic, cultural and political “islands?” Already at school we learned too much about migrations of peoples, economic contacts, influences on art styles, conquests, and the rise, expansion and fall of empires to believe that. The (highly (...) improbable) theory that certain archaeological finds in America suggest, or even prove, Mediterranean influence (e.g., the arrival of Phoenician ships), or the alleged Viking discovery of America centuries before Columbus, or Thor Heyerdahl's adventurous journey to prove South American influence on remote Pacific islands did not fail to cause widespread interest and even excitement (although many scholars still feel that Heyerdahl's epic adventure, thrilling as it is, failed to prove what it set out to prove). The island of Madagascar is pretty close to the African continent, but its language exhibits more points of contact with Polynesian than with African tongues. And the blow-bellows used by Malagache smiths are similar to those used in Malaysia and unlike those known to African metalworkers. Clearly the Polynesians, those great ancient mariners, sailed further than originally seemed likely. Musicologists studying the cantillation of the Hebrew Bible in the liturgy of the ancient Jewish communities on the Malabar coast in India discovered to their surprise that it was similar to the cantillation not of the Babylonian but of the Yemenite Jews! This surprise was, of course, no surprise to those who knew anything about trade-winds and shipping routes between South Arabia and the Indian coast. Historians of religion, even more than general historians, studying the spread and expansion of religious ideas and movements have realised long ago that the beginning of all wisdom is a basic knowledge of economic geography. (shrink)

During an Australian qualitative and empirical study looking at lesbian, gay, bisexual, and transgender client's experiences of counseling, and counselor's experiences of working with minority clients, a large body of unsolicited data emerged related to experiences of religious-based homophobia. Analysis of the data suggests that a lifelong process of posttraumatic recovery for many lesbian, gay, bisexual, and transgender people follows prior experiences of religious-based homophobia. This paper discusses the sociological debate related to how counselors find themselves at the crossroad between (...) a healthy lifestyle model of homosexuality based in well established contemporary professional ethics versus long standing religious-based attitudes and constraints toward homosexuality. This intersection of conflicting beliefs generates a controversial social and political environment in which counselors must make a basic decision to either support minority clients according to ethical guidelines or to side with socially conservative constructs that, rightly or wrongly, rely largely on Western religious traditions. (shrink)

Q: What did the elephant say to the naked man?A: It looks O.K., but can you breathe through it?Let me begin by justifying that joke for those of you didn’t find it funny. The relationship between the morphology of the physical organs and their activities has long been a vexed issue in the philosophy of biology: the question of whether structure determines function is of course of contemporary importance in evolutionary theory. That there was a relationship between structure and function (...) was not in general a matter of doubt to the Greek theoretical biologists: but both the extent, and crucially the direction, of the dependence was. And the question need not be restricted to a consideration of the function of a particular part in isolation: when Aristotle takes issue with Anaxagoras for asserting that humans are the most intelligent species because they have hands, claiming rather that they have hands because they are intelligent, he is making a claim not just about the direction of explanation involved, but he is also implicitly at least indicating the scope of such explanations. For Aristotle, intelligence is one of the human functions: and that function necessitates the existence and development of certain organic structures. (shrink)

In this article I consider a two-page autobiographical recount which appears at the end of Nelson Mandela's book Long Walk to Freedom as a summary of his life and what he has learned from it. My aim is to illustrate the role of a detailed analysis of single texts in the field of discourse analysis, as opposed to studies of selected variables across a corpus of texts. The analysis is conducted within the general theoretical framework of systemic functional linguistics, with (...) special attention to transitivity, mood, theme, grammatical metaphor, lexical relations, conjunction, tense, phase, process type, hierarchy of periodicity, polarity, continuity, elaboration, extension and the analysis of images in multimodal text. Through these procedures I show the way in which Mandela reconciles the linear unfolding of his life history with the deepening understanding of freedom that gives meaning to his life - by means of a spiral texture which returns again and again to the meaning of freedom at different levels of abstraction. The effect, I think, is inspirational - with no tinge of bitterness or betrayal; rather a message of hope and wisdom - grace personified. The approach exemplifies a positive style of discourse analysis that focuses on hope and change, by way of complementing the deconstructive exposé associated with critical discourse analysis. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

The possibility that the Greeks used heraldic symbols or blazons was first explored a long time ago. The question has been revived recently by a French scholar in an article entitled ‘Les “blazons” des villes grecques’. It is of wide general interest, and of particular interest to numismatists who are concerned with the curious group of coins of Euboic standard bearing various simple devices , sometimes placed within what appears to be the circle of a shield. Various scholars, including C. (...) T. Seltman, ascribed these coins to sixth-century Athens; Seltman's particular contribution to the problem of their identification consisted in the explanation of the diverse anepigraphic types of this group of coins as the ‘heraldic’ devices or blazons of the great gene or noble houses of early Athens. In particular he pointed out that the same devices appeared also in Attic black-figured vases on the shields of deities, heroes, and unidentified hoplites, and proposed the theory that the vase-painters were copying what they saw in the streets of Athens, namely the shield-devices of the men-at-arms of Athens' leading families. (shrink)

It is a pleasure to read Hume, and to watch him explore recalcitrant problems with agility of mind and grace of style. Ironically these twin abilities have worked against each other from the beginning, in the first place because in the matter of writing Hume was an innovator — nobody before him had so successfully albeit unwittingly adapted French syntax to the writing of English-and-Scottish - and in the second place because on the grace of his style subtleties of thought (...) flow past his readers, who then accuse him of obscurity. So abstruse were his writings to his contemporaries that he failed to achieve the literary recognition for which he craved; and even today, long after the elegance of his style has been received, it is said by Passmore that Hume in contrast to Berkeley ‘was a philosophical puppy-dog, picking up and worrying one problem after another, always leaving his teeth-marks in it, but casting it aside when it threatened to become wearisome.’ Similarly Selby-Bigge says in his introduction to the Enquiries:His pages, especially those of the Treatise, are so full of matter, he says so many things in so many different ways and different connexions, and with so much indifference to what he has said before, that it is very hard to say positively that he taught, or did not teach, this or that particular doctrine. He applies the same principles to such a great variety of subjects that it is not surprising that many verbal, and some real inconsistencies can be found in his statements. He is ambitious rather than shy of saying the same thing in different ways, and at the same time he is often slovenly and indifferent about his words and formulae. This makes it easy to find all philosophies in Hume, or, by setting up one statement against another, none at all. (shrink)

It is a pleasure to read Hume, and to watch him explore recalcitrant problems with agility of mind and grace of style. Ironically these twin abilities have worked against each other from the beginning, in the first place because in the matter of writing Hume was an innovator — nobody before him had so successfully albeit unwittingly adapted French syntax to the writing of English-and-Scottish - and in the second place because on the grace of his style subtleties of thought (...) flow past his readers, who then accuse him of obscurity. So abstruse were his writings to his contemporaries that he failed to achieve the literary recognition for which he craved; and even today, long after the elegance of his style has been received, it is said by Passmore that Hume in contrast to Berkeley ‘was a philosophical puppy-dog, picking up and worrying one problem after another, always leaving his teeth-marks in it, but casting it aside when it threatened to become wearisome.’ Similarly Selby-Bigge says in his introduction to the Enquiries:His pages, especially those of the Treatise, are so full of matter, he says so many things in so many different ways and different connexions, and with so much indifference to what he has said before, that it is very hard to say positively that he taught, or did not teach, this or that particular doctrine. He applies the same principles to such a great variety of subjects that it is not surprising that many verbal, and some real inconsistencies can be found in his statements. He is ambitious rather than shy of saying the same thing in different ways, and at the same time he is often slovenly and indifferent about his words and formulae. This makes it easy to find all philosophies in Hume, or, by setting up one statement against another, none at all. (shrink)

As critical incidents and terrorist threats are on the increase, the military/SWAT (Special Weapons and Tactics) aspects of U.S. civilian policing are being expanded. The person called upon as a last resort to kill the criminal agent has a unique position on the SWAT team. The police sniper is asked to kill with premeditation and usually not in a situation of self-defense. Very little appears in the ethics literature analyzing the morality of the sniper role. This paper will tentatively outline (...) a process of analysis that draws upon the framework of principles associated with the just-war tradition. Elements examined are the ends of sniper killing, intention and motives, relevant emotions, and implementation means used. The conclusion is that a plausible case can be made for the moral justification of such killing as long as certain conditions or tests are met. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:46. HUME AND THE FUTURE OF THE SOCIETY OF NATIONS In the section of Hume's Treatise of Human Nature entitled Of the laws of nations (Section XI of Book III) he says: Political writers tell us, that in every kind of intercourse, a body politic is to be consider 'd as one person; and indeed this assertion is so far just, that different nations, as well as private persons, (...) require mutual assistance; at the same time that their selfishness and ambition are perpetual sources of war and discord.But tho' nations in this particular resemble individuals, yet as they are very different in other respects, no wonder they regulate themselves by different maxims, and give rise to a new set of rules, which we call the laws of nations. 1 He goes on to give examples of such laws:the sacredness of the persons of ambassadors, the declaration of war, the abstaining from poison'd arms, with other duties of that kind, which are evidently calculated for the commerce, that is peculiar to different.societies. (T 567) Hume then tells us in the next paragraph that such laws of nations may be added to the three laws of nature (that possessions should be stable, that possessions should be transferable by consent, and that promises or contracts should be kept) but that these laws of nations do not supersede the laws of nature; that is, they do not make the laws of nature irrelevant to relations among nation-states. In fact, the morality among nation-states involves the same kinds of obligations as morality among private persons, but the obligations are not as binding. The obligations of nation-states to each other can more readily be overridden by concerns of self-interest than would be legitimate in the case of private persons because nation-states are more nearly able to maintain themselves without external assistance than are individual persons. In Hume's words,... tho' the 47. morality of princes has the same extent, yet it has not the same force as that of private persons (T 558) because tho' the intercourse of different states be advantageous, and even sometimes necessary, yet it is not so necessary nor advantageous as that among individuals, without which 'tis utterly impossible for human nature ever to subsist. (T 569) In the last paragraph of this section Hume addresses himself to the question of the proportion these two species of morality bear to each other. (T 569) He says that we can never give any precise answer (T 569) and that the proper proportion is exhibited in the actual practice of the world. He takes this fact as showing that all men recognize that the rules of morality, both among private individuals and among nation-states, arise from human conventions, and from the interest, which we have in the preservation of peace and order. (T 569) When discussing the same issue in his Enquiry concerning the Principles of Morals Hume is more succinct. The observance of justice, though useful among them [nations], is not guarded by so strong a necessity as among individuals; and the moral obligation holds proportion with the usefulness. 2 """ The moral obligations of individuals to each other is thus greater than that of nations to each other because keeping the rules of justice is inore useful in the former case than in the latter. But Hume did not live in an age of atomic weapons, long-range missiles, and precision-guided munitions. Furthermore, the nations of the world are now much more interdependent than in his day, not only with regard to where they get the resources they need but also with regard to what they do with their wastes. There seems to be little roo.? _or dtubt that the utility of following the rules of justice among nations is much greater now than it was in the eighteenth 48. century. Since a nuclear war might mean the end of the human species, the utility of justice among nations seems to be approaching, perhaps even surpassing, the utility which moral rules have at the level of private persons. In view of this changed situation, I intend to review what Hume has... (shrink)

Q: What did the elephant say to the naked man?A: It looks O.K., but can you breathe through it?Let me begin by justifying that joke for those of you didn’t find it funny. The relationship between the morphology of the physical organs and their activities has long been a vexed issue in the philosophy of biology: the question of whether structure determines function is of course of contemporary importance in evolutionary theory. That there was a relationship between structure and function (...) was not in general a matter of doubt to the Greek theoretical biologists: but both the extent, and crucially the direction, of the dependence was. And the question need not be restricted to a consideration of the function of a particular part in isolation: when Aristotle takes issue with Anaxagoras for asserting that humans are the most intelligent species because they have hands, claiming rather that they have hands because they are intelligent, he is making a claim not just about the direction of explanation involved, but he is also implicitly at least indicating the scope of such explanations. For Aristotle, intelligence is one of the human functions: and that function necessitates the existence and development of certain organic structures. (shrink)

Kolakowski, who was born in 1927, has long been known as one of the most original and exciting post-Stalinist Polish intellectuals. And this collection of essays show why he deserves this reputation. There is wit, irony, insight, and radical critique evidenced throughout. His discussion of "Karl Marx and the Classical Definition of Truth" provides a fresh, provocative, and fascinating interpretation of Marx's epistemology. His criticism of Stalinist Marxism and the analogies he draws with the history of theology are among the (...) most intelligent and incisive criticisms developed. There is a theme that runs throughout these essays--it is the theme of the individual's moral responsibility in contemporary society. His criticism of orthodoxy including Marxist orthodoxy is pervaded by the spirit of rational criticism that preserves and fosters the best in the Marxist tradition. The book unfortunately lacks a badly needed introduction and there are no bibliographical references for many of the papers.--R. J. B. (shrink)

Seventy six papers collected together to honor Dr. S. Radhakrishnan, the philosopher-statesman of India. The selection of papers reflects Radhakrishnan's life long task of encouraging a genuine encounter between the thought of the east and the west.—R. J. B.

Treatises of this length and care are rarely written today and in the course of Cumming's explorations there is an enormous richness of insight, commentary, and analysis of the history of liberal thought. But at the same time, it is difficult to keep the main themes of this study in clear focus. One gets the impression that Cumming originally set out to understand liberal thought as expressed by John Stuart Mill and found himself digging into origins. Dig he does, taking (...) into account in his intellectual journey through Western Civilization: Polybius, Cicero, Augustine, Petrarch, Machiavelli, Hobbes, Locke, Hume, Bentham, James Mill and many others along the way. One can learn a great deal about this western political tradition by following Cumming's patient explications and critiques. In the foreground is always John Stuart Mill and at times Cumming fosters the misimpression that Mill culminates this entire tradition. Yet Cumming's attitude toward Mill is strangely ambivalent and toward the end of this study, Cumming seems to be more fascinated with the stages of Mill's development and his mental crisis rather than with the integrity and coherence of his political philosophy. Liberal political thought has recently come in for a severe polemical thrashing and Cumming's study might have been a detailed, eloquent defense of this tradition. But the study is deficient in attempting to show how liberal thought can directly meet the numerous criticisms that have been raised from many sides. In the preface, Cumming reports that the manuscript was on the way to the typesetters during the upheaval at Columbia when police arrived on campus. This episode symbolizes the strange feeling one has that the book is dated by the time it appeared. Despite its weaknesses as an apology for liberal thought, it excels in making us sensitive to its long and vital history.--R. J. B. (shrink)

Was Hegel a good guy or a bad guy? Was he a conservative or a liberal? Was he a proto-fascist as Popper has claimed or the greatest philosophic champion of human freedom as Marcuse has claimed? The debate has been a long and heated one and in this volume, Kaufmann includes a number of articles written in English that are concerned with these related issues. But one feels that something is missing from these heated controversies and that is Hegel himself. (...) As Kaufmann himself says: "Whoever wants to know what Hegel's political philosophy really was, must in the end go back to Hegel himself...." These papers do, however, succeed in giving one a sense of what are key issues in understanding and assessing Hegel's political philosophy.--R. J. B. (shrink)

Everywhere the 1990s have been characterized by an odd mixture of ideological triumphalism-Fukuyama's "end of history" being only the crassest example-and of ideological uncertainty-can there be, should there be, a "third way"? For all its pretensions to universality, the "New World Order" has never lost a fragility in appearance. Students of historiography can scarcely be surprised to learn that an uneasiness over the present and future has in turn frequently entailed uncertainty about the past and particularly about those parts of (...) the past which had seemed most able to give clear and significant "lessons."One evident example is the history of what in my Explaining Auschwitz and Hiroshima I called the "long" Second World War, that is, that crisis in confidence in the relationship between political and economic liberalism and the nation-state which, by the end of 1938, had left only Britain, France, the Low Countries, and Scandinavia as in any sense preserving those "liberal" freedoms which had spread across Europe since 1789. In this article, I briefly review the most recent difficulties World War II combatant societies have had in locating a usable past in the history of those times. However, my major focus is on the specific case of Italy, very much a border state in the Cold War system, and today the political home of an "Olive Tree" and a "Liberty Pole" whose historical antecedents and whose philosophical base for the future are less than limpid. 1990s Italian historians thus give very mixed messages about the Fascist past; these are the messages I describe and decode. (shrink)

Until fairly recently a common way of doing history of science was to pick up an important strand of contemporary scientific thought and to trace its origin back to the philosophical tangle of the scientific revolution. This approach conveniently by-passed the breakdowns of once useful and pervasive theories, and neglected the long intellectual journeys along devious routes. History of science read like a success story; the pioneers who failed were neither dismissed nor excused; they were simply ignored. The historian knew (...) what he was hunting for and he was careful to limit his search to areas where his quarry was sure to be found. This method, which has been dubbed the precursor-view, stands in contrast—albeit, not in opposition—to the contextual method, which aims at a better understanding of the actual thought-processes of the early scientists. On this second view, history of science must not only account for present theories in the light of past developments, it must also assess old theories in terms of the scientist's conceptual framework, and judge them against the background of the world picture of his age. This may lead the historian down the blind alleys of the past, chasing spurious attempts at explaining the nature of physical reality, but it can clear the ground for a less anachronistic interpretation of the emergence of modern science and the actual process of discovery. History of science acts as a winnowing fork, but we cannot suppose that the discoverer himself always separated the wheat from the chaff, and we must be ever wary of equating the dream with the task. (shrink)

There is a long tradition of characterizing man as the talking animal. However, the remarkable ability of using pictures also belongs to human beings, after all we know empirically so far. Are there conceptual reasons for that coincidence? Such a question belongs to the general science of language (linguistics) and philosophy of language just as well as to general visualistics (image science) - a discipline just emancipating itself from art history. We here take the visualistics point of view. A first (...) recapitulation of the two abilities to use words or pictures lists several similarities and distinctions. A well-known disparity between pictures and words in the relation to perception can be determined by differences in the modes of usage during the corresponding sign acts. Furthermore, there are distinct ways for splitting up the pictorial or verbal sign acts into figure and ground. Such a structural comparison can only clarify conceptual relations; it cannot explain that the conceptual structure ought to be like that, in contrast to concept-genetic considerations. Correspondingly the discussion is extended to a concept-genetic sketch of the abilities to use language or pictures. This shifts the focus of attention to the concept of sortal objects and the concept of contexts of behavior. They allow us to analyze more precisely the relation between the two abilities in question, in particular as something depending on the function of context building, which enables human beings to communicatively access contexts apart from the actual situation of behavior. We finally gain arguments that characterize that relation as one of mutual dependency, and even lead to an understanding of the concept of inner images - or rather: a concept of imagination. (shrink)

There has been a long tradition of characterizing man as the animal that talks. However, the remarkable ability of using pictures also only belongs to human beings, after all we know empirically so far. Are there conceptual reasons for that coincidence? The paper is dedicated to a philosophical programme of “concept-genetic” considerations dealing in particular with the dependencies between those two abilities: The conceptual relation between the competence to use assertive language and the faculty of employing pictures must be conceived (...) of as being much closer than usually expected. Indeed we conclude, there cannot be creatures with only one of them. (shrink)

The life-long correspondence of David K. Lewis, one of the most influential philosophers of the twentieth century, reveals the development, breadth, and depth of his philosophy in its historical context. The second of this two volume collection focuses on his contributions to philosophical questions of language, mind, and epistemology.

The title of this edition is quite misleading and the edition is disappointing. The Dietz Verlag edition of Marx's Grundrisse der Kritik der politischen Ökonomie is over a thousand pages long. Virtually unavailable until recently, it is considered by many to be among Marx's most interesting and important works. It consists primarily of Marx's unpublished writings from 1857-1858. A serious study of the Grundrisse must be made for a full understanding of Marx. It places the discussion of the 'young' vs. (...) the 'old' Marx on a new level of sophistication because here is a work written by the mature Marx that is pervaded with Hegelian themes. It contains highly interesting speculations about the Asiatic mode of production, the theory of surplus value, and the possibility of the development of a middle class, which is not available in Marx's other writings. McLellan, Nicolaus, Marcuse, Lichtheim, and others have noted the importance of the Grundrisse for gaining new insight into Marx's thought. Unfortunately, McLellan has translated what amounts to about one tenth of this work in a manner which while it whets one's intellectual appetite is not very useful for pursuing or pinning down Marx's reflections in the Grundrisse. These bits and fragments will have to do until we have a full translation of the Grundrisse.--R. J. B. (shrink)

In 1951 these editors began publication of a monumental critical edition of Plotinus' works. Now Oxford is making available a slightly revised editio minor in its series of classical texts. The textual revision is accompanied by a long list of variants. Thus this text, which includes Porphyry's life of Plotinus and Enneads I-III, supersedes the earlier editio major. The critical apparatus is considerably reduced, but should prove adequate to all but serious textual scholars. This edition will probably remain the standard (...) Plotinus text for many years.—R. J. W. (shrink)

Kolakowski, who was born in 1927, has long been known as one of the most original and exciting post-Stalinist Polish intellectuals. And this collection of essays show why he deserves this reputation. There is wit, irony, insight, and radical critique evidenced throughout. His discussion of "Karl Marx and the Classical Definition of Truth" provides a fresh, provocative, and fascinating interpretation of Marx's epistemology. His criticism of Stalinist Marxism and the analogies he draws with the history of theology are among the (...) most intelligent and incisive criticisms developed. There is a theme that runs throughout these essays--it is the theme of the individual's moral responsibility in contemporary society. His criticism of orthodoxy including Marxist orthodoxy is pervaded by the spirit of rational criticism that preserves and fosters the best in the Marxist tradition. The book unfortunately lacks a badly needed introduction and there are no bibliographical references for many of the papers.--R. J. B. (shrink)

John J. McDermott, who has already distinguished himself by publishing the best available selection of William James' writings, has now performed the same task for Josiah Royce. Although Josiah Royce is normally classified as one of the American "classical" philosophers, he is probably the least read of these philosophers. These skillfully edited volumes may go a long way to making Royce's comprehensive and complex thought available. There is a brief introduction in which McDermott nicely conveys a "feel" for the man (...) and his thought, especially as it manifests the spirit of American philosophy. The selections are grouped under a number of headings, each preceded with a short commentary. McDermott has deliberately aimed at comprehensiveness, and I suspect even those familiar with some of Royce's work may be surprised by the variety of his investigations. There is a sixty-page annoted bibliography prepared by Ignas K. Skrupsklelis which is the most complete bibliography of Royce's writings available. Although there are no selections from The Problem of Christianity, the University of Chicago Press has recently published this book with a new introduction by John E. Smith. The Letters of Josiah Royce is also being published by Chicago. Painstaking, intelligent editing of philosophic texts is all too rare in our time. McDermott is to be congratulated on a superb job, and the University of Chicago Press is to be praised for undertaking this extensive publication of Royce's work.--R. J. B. (shrink)

It is a shame that this volume which was started a decade ago should have been so long in preparation. The result is that many of the critical papers have been superseded by more recent investigations. Nevertheless, there are a number of respects in which this is an extremely valuable book. It contains Carnap's autobiography, written in the direct and careful style that is so characteristic of his work. Carnap also patiently and systematically answers the objections raised by his critics. (...) And there is an invaluable annotated bibliography of his writings. But the dominant impression of the volume as a whole is that of summing up the contribution and limitations of one of the twentieth-century's most important and influential philosophers.—R. J. B. (shrink)

This is not a long book—but it is surprising that it is as long as it is. The Cyrenaics are one of a number of more or less shadowy philosophical schools which emerged in the Greek world in the 4th century BC and later. Well known are Plato’s Academy and Aristotle’s Lyceum; and relatively well served by the tradition are the Stoics and the Epicureans, as well as the various later varieties of sceptic; while the Cynics are remembered at least (...) by reputation and anecdote. The Cyrenaics are altogether murkier. No text composed by a Cyrenaic philosopher of any period survives. Our knowledge of them rests on a handful of sources, almost all of them reports of doctrine rather than genuine fragments, none of them detailed, most of them late, generally from the works of commentators, at best neutral, at worst positively hostile, all with their own axes to grind. The best testimony consists of a mere three pages in Sextus Empiricus’s invaluable doxography of different accounts of the criterion of truth in adversus Mathemticos 7. (shrink)

The life-long correspondence of David K. Lewis, one of the most influential philosophers of the twentieth century, reveals the development, breadth, and depth of his philosophy in its historical context. The first of this two volume collection of letters focuses on his contributions to metaphysics, arguably where he made his greatest impact.

In this article, we propose the Fair Priority Model for COVID-19 vaccine distribution, and emphasize three fundamental values we believe should be considered when distributing a COVID-19 vaccine among countries: Benefiting people and limiting harm, prioritizing the disadvantaged, and equal moral concern for all individuals. The Priority Model addresses these values by focusing on mitigating three types of harms caused by COVID-19: death and permanent organ damage, indirect health consequences, such as health care system strain and stress, as well as (...) economic destruction. It proposes proceeding in three phases: the first addresses premature death, the second long-term health issues and economic harms, and the third aims to contain viral transmission fully and restore pre-pandemic activity. -/- To those who may deem an ethical framework irrelevant because of the belief that many countries will pursue "vaccine nationalism," we argue such a framework still has broad relevance. Reasonable national partiality would permit countries to focus on vaccine distribution within their borders up until the rate of transmission is below 1, at which point there would not be sufficient vaccine-preventable harm to justify retaining a vaccine. When a government reaches the limit of national partiality, it should release vaccines for other countries. -/- We also argue against two other recent proposals. Distributing a vaccine proportional to a country's population mistakenly assumes that equality requires treating differently situated countries identically. Prioritizing countries according to the number of front-line health care workers, the proportion of the population over 65, and the number of people with comorbidities within each country may exacerbate disadvantage and end up giving the vaccine in large part to wealthy nations. (shrink)

Strategies to involve agribusiness in the development of sustainable agricultural systems have been limited by the lack of a comprehensive conceptual framework for identifying the most critical supportive policies, programs and regulations. In this paper, we propose an efficiency/substitution/redesign framework to categorize strategies for modifying agribusiness practices. This framework is then used to identify a diverse range of short, medium, and long-term strategies to be pursued by governments, community groups, academics and agribusiness to support the transition. Strategies discussed include corporate (...) greening, ethical investment, changing the legal status of the corporaton, new business forms and the development of ecological economics. (shrink)

There has been a long tradition of characterizing man as the animal that is capable of propositional language. However, the remarkable ability of using pictures also only belongs to human beings. Both faculties however depend conceptually on the ability to refer to absent situations by means of sign acts called 'context building'. The paper investigates the combined roles of quasi-pictorial sign acts and proto-assertive sign acts in the situation of initial context building, which, in the context of “concept-genetic” considerations, aims (...) for a philosophical explanation of the anthropological functon of pictures and their relation to imagination. (shrink)

There has been a long tradition of characterizing man as the animal that talks. However, the remarkable ability of using pictures also only belongs to human beings, after all we know empirically so far. Are there conceptual reasons for that coincidence? Such a question belongs to the philosophy of language just as well as to philosophical visualistics. Comparing the two abilities to use words or pictures yields several similarities as well as distinctions. A well-known conceptual disparity between pictures and words (...) appears in their relation to perception: the difference can be further determined in an act-theoretic manner by four modes of use of the sign vehicles during the corresponding sign acts. Furthermore, the figure/ground dichotomy means something different for language uses and picture uses. In both cases, however, there is a close relation to the function of context building, by which humans are able to communicate not only with respect to the present situation of behavior but with respect to arbitrary contexts as well. Although the structural comparison does clarify the conceptual relations, it cannot explain that the conceptual structure ought to be like that. Therefore, the paper concludes with the programme of a "concept-genetic" consideration of the two abilities (i.e., to use propositional language or to use pictures) that is able to give us such a foundation. (shrink)

XLRI, in association with a few Tata Group companies, established the XLRI-JRD Tata Foundation in Business Ethics in 1991 to mark their long-standing commitment and contribution to business ethics in India. The foundation seeks to address this by publicly affirming the urgent need for ethics in business and the need to bring about a conducive culture in which it can thrive.

Núñez and colleagues (2019) question whether cognitive science still exists “as a coherent academic field with a well‐defined and cohesive interdisciplinary research program.” This worry may be premature on two grounds. First, we are not convinced that the Lakatosian criterion of coalescence around a core framework is the best standard for judging whether a field is well‐defined and productive. Second, although we acknowledge that cognitive science is not as visible as we would like, we doubt that this low profile accurately (...) reflects the state of actual research and teaching programs based on the cognitive science approach. (shrink)

Núñez and colleagues (2019) question whether cognitive science still exists “as a coherent academic field with a well‐defined and cohesive interdisciplinary research program.” This worry may be premature on two grounds. First, we are not convinced that the Lakatosian criterion of coalescence around a core framework is the best standard for judging whether a field is well‐defined and productive. Second, although we acknowledge that cognitive science is not as visible as we would like, we doubt that this low profile accurately (...) reflects the state of actual research and teaching programs based on the cognitive science approach. (shrink)

Background:Surveillance technology such as tag and tracking systems and video surveillance could increase the freedom of movement and consequently autonomy of clients in long-term residential care settings, but is also perceived as an intrusion on autonomy including privacy.Objective:To explore how clients in residential care experience surveillance technology in order to assess how surveillance technology might influence autonomy.Setting:Two long-term residential care facilities: a nursing home for people with dementia and a care facility for people with intellectual disabilities.Methods:Ethnographic field study.Ethical considerations:The boards (...) representing clients and relatives/proxies of the clients were informed of the study and gave their written consent. The clients’ assent was sought through a special information leaflet. At any time clients and/or proxy were given the option to withdraw from the study. The research protocol was also reviewed by a medical ethics committee.Findings:Our findings show a pattern of two themes: (1) coping with new spaces which entailed clients: wandering around, getting lost, being triggered, and retreating to new spaces and (2) resisting the surveillance technology measure because clients feel stigmatized, missed the company, and do not like being “watched.”Conclusion:Client experiences of surveillance technology appear to entail a certain ambivalence. This is in part due to the variety in surveillance technology devices, with each device bringing its own connotations and experiences. But it also lies in the devices’ presupposition of an ideal user, which is at odds with the actual user who is inherently vulnerable. Surveillance technology can contribute to the autonomy of clients in long-term care, but only if it is set in a truly person-centered approach. (shrink)

Economic markets are not morally free zones. Contrary to popular misconceptions, market functioning rests on the ethical principles of fairness and voluntariness. This ethical foundation can be traced back at least to moral philosopher Adam Smith, one of the founders of modern economics. In the inconspicuous form of microeconomic axioms, these moral foundations are preserved. Thus, virtually all “neo-classic” economic concepts presuppose a market ethics of fairness and voluntariness. In a world of pervasive uncertainty on the long-term development of the (...) human-environment interaction, the protection of the global life-support systems is an important test case for the scope of the ethical content of market ethics. We review risk protection strategies in the face of this uncertainty that are (i) based on the insurance effect of biological diversity, and (ii) that employ a safe minimum standard (SMS). Because the fairness principle of market ethics requires that economic agents who cause “external” costs must, at least, compensate those who are burdened with these costs, the interests of future generations have to be included in responsible economic decision-making. The market and market ethics approach is applied to the analysis of a SMS for biological diversity, and to the inherent problems of such an approach. At the microeconomic level of individual decision-making, an unconditional protection is supported by market ethics neither for the putative interests of future generations nor for biological diversity: Poor people who struggle to cover their basic needs cannot not be required to care for biological diversity. In all other cases, the protection of biological diversity in favour of future generations is supported—if costs are not “unacceptably high”. At which cost level this point is approached, market ethics is not designed to decide. (shrink)

Human societies are extraordinarily cooperative compared to those of most other animals. In the vast majority of species, individuals live solitary lives, meeting to only to mate and, sometimes, raise their young. In social species, cooperation is limited to relatives and (maybe) small groups of reciprocators. After a brief period of maternal support, individuals acquire virtually all of the food that they eat. There is little division of labor, no trade, and no large scale conflict. Communication is limited to a (...) small repertoire of self-verifying signals. No one cares for the sick, or feeds the hungry or disabled. The strong take from the weak without fear of sanctions by third parties. Amend Hobbes to account for nepotism, and his picture of the state of nature is not so far off for most other animals. In contrast, people in even the simplest human societies regularly cooperate with many unrelated individuals. Human language allows low-cost honest communication of virtually unlimited complexity. The sick are cared for, and sharing leads to substantial flows of food from the middle aged to the young and old. Division of labor and trade are prominent features of every historically known human society, and archaeology indicates that they have a long history. Violent conflict among sizable groups is common. In every human society, social life is regulated by commonly held moral systems that specify the rights and duties of individuals enforced, albeit imperfectly, by third party sanctions. (shrink)